144025-03-6 | 2,4-Difluorophenylboronic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$8.00	$5.00
5g	98%	in stock	$9.00	$6.00
10g	98%	in stock	$10.00	$7.00
25g	98%	in stock	$25.00	$17.00
100g	98%	in stock	$94.00	$66.00

Description

• Catalog Number: AA70827
• Chemical Name: 2,4-Difluorophenylboronic acid
• CAS Number: 144025-03-6
• Molecular Formula: C6H5BF2O2
• Molecular Weight: 157.9105064
• MDL Number: MFCD01318998
• SMILES: Fc1ccc(c(c1)F)B(O)O

Computed Properties

• Complexity: 134
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1

Upstream Synthesis Route

2,4-Difluorophenylboronic acid is a versatile compound widely used in chemical synthesis as a key building block in the preparation of various pharmaceuticals, agrochemicals, and advanced materials. With its unique chemical properties, this acid serves as a valuable tool for organic chemists in the construction of complex molecular structures. Its ability to participate in Suzuki-Miyaura cross-coupling reactions enables the efficient formation of carbon-carbon bonds, facilitating the synthesis of biologically active compounds and functional materials. Additionally, 2,4-Difluorophenylboronic acid can be employed for the modification of natural products, as well as in the development of new catalysts and ligands. Its presence in the chemical synthesis toolbox underscores its significance in driving innovation and discovery in the field of organic chemistry.

Literature

• Bis[3,5-difluoro-2-(4-methyl-pyridin-2-yl)phenyl-κC,N](picolinato-κN,O)iridium(III) chloro-form monosolvate.

  Acta crystallographica. Section E, Structure reports online 20110901

• 2,4-Difluoro-phenyl-boronic acid.

  Acta crystallographica. Section E, Structure reports online 20090101

• 1-(2',4'-Difluoro-biphenyl-4-yl)ethanone.

  Acta crystallographica. Section E, Structure reports online 20081001