1445993-26-9 | Mivebresib

Packsize	Purity	Availability	Price	Discounted Price
1mg	97%	in stock	$16.00	$11.00
2mg	97%	in stock	$27.00	$19.00
5mg	97%	in stock	$39.00	$28.00
10mg	97%	in stock	$59.00	$41.00
25mg	97%	in stock	$100.00	$70.00

Description

• Catalog Number: AA72138
• Chemical Name: Mivebresib
• CAS Number: 1445993-26-9
• Molecular Formula: C22H19F2N3O4S
• Molecular Weight: 459.4658
• MDL Number: MFCD30377200
• SMILES: CCS(=O)(=O)Nc1ccc(c(c1)c1cn(C)c(=O)c2c1cc[nH]2)Oc1ccc(cc1F)F

Computed Properties

• Complexity: 834
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 32
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 6
• XLogP3: 2.9

Literature

• Discovery of N-(4-(2,4-Difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide (ABBV-075/Mivebresib), a Potent and Orally Available Bromodomain and Extraterminal Domain (BET) Family Bromodomain Inhibitor.

  Journal of medicinal chemistry 20171026