1463-10-1 | 5-Methyluridine

Packsize	Purity	Availability	Price	Discounted Price
10g	98%	in stock	$9.00	$6.00
25g	97%	in stock	$15.00	$11.00
500g	98%	in stock	$251.00	$176.00

Description

• Catalog Number: AA64449
• Chemical Name: 5-Methyluridine
• CAS Number: 1463-10-1
• Molecular Formula: C10H14N2O6
• Molecular Weight: 258.2280
• MDL Number: MFCD00006535
• SMILES: OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cc(C)c(=O)[nH]c1=O

Computed Properties

• Complexity: 409
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 4
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 2
• XLogP3: -1.6

Literature

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  Journal of the American Chemical Society 20120801

• Identification of the enzyme responsible for N1-methylation of pseudouridine 54 in archaeal tRNAs.

  RNA (New York, N.Y.) 20120301

• Two-step efficient synthesis of 5-methyluridine via two thermostable nucleoside phosphorylase from Aeropyrum pernix.

  Bioorganic & medicinal chemistry letters 20120301

• Improved synthesis of 2'-deoxyadenosine and 5-methyluridine by Escherichia coli using an auto-induction system.

  World journal of microbiology & biotechnology 20120201

• Defining a process operating window for the synthesis of 5-methyluridine by transglycosylation of guanosine and thymine.

  Journal of biotechnology 20110110

• The complete genome sequence of 'Candidatus Liberibacter solanacearum', the bacterium associated with potato zebra chip disease.

  PloS one 20110101

• A 5'-uridine amplifies miRNA/miRNA* asymmetry in Drosophila by promoting RNA-induced silencing complex formation.

  Silence 20110101

• Differential effects of nucleotide analogs on scanning-dependent initiation and elongation of mammalian mRNA translation in vitro.

  RNA (New York, N.Y.) 20100601

• Long-term AZT exposure alters the metabolic capacity of cultured human lymphoblastoid cells.

  Toxicological sciences : an official journal of the Society of Toxicology 20100501

• Mutagenesis of the modified bases, m(5)U1939 and psi2504, in Escherichia coli 23S rRNA.

  Biochemical and biophysical research communications 20100205

• A study on the interaction between 5-Methyluridine and human serum albumin using fluorescence quenching method and molecular modeling.

  Journal of molecular modeling 20100201

• Stereochemical mechanisms of tRNA methyltransferases.

  FEBS letters 20100121

• [Determination of protein in biological samples by synchronous fluorescence].

  Guang pu xue yu guang pu fen xi = Guang pu 20090901

• Molecularly imprinted polymer of 5-methyluridine for solid-phase extraction of pyrimidine nucleoside cancer markers in urine.

  Bioorganic & medicinal chemistry 20081001

• Crystallization and preliminary X-ray crystallographic characterization of TrmFO, a folate-dependent tRNA methyltransferase from Thermotoga maritima.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20080301

• Selenium derivatization of nucleic acids for phase and structure determination in nucleic acid X-ray crystallography.

  International journal of molecular sciences 20080301

• Metabolic signature of breast cancer cell line MCF-7: profiling of modified nucleosides via LC-IT MS coupling.

  BMC biochemistry 20070101

• A counterintuitive Mg2+-dependent and modification-assisted functional folding of mitochondrial tRNAs.

  Journal of molecular biology 20060929

• 3D-QSAR studies on antitubercular thymidine monophosphate kinase inhibitors based on different alignment methods.

  Bioorganic & medicinal chemistry letters 20060215

• Temperature-dependent biosynthesis of 2-thioribothymidine of Thermus thermophilus tRNA.

  The Journal of biological chemistry 20060127

• Synthesis and anti-viral activity of a series of d- and l-2'-deoxy-2'-fluororibonucleosides in the subgenomic HCV replicon system.

  Bioorganic & medicinal chemistry 20050301

• Kilo-scale synthesis process for 2'-O-(2-methoxyethyl)-pyrimidine derivatives.

  Nucleosides, nucleotides & nucleic acids 20050101

• Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase.

  Bioorganic & medicinal chemistry letters 20030915

• Characterization of the 23 S ribosomal RNA m5U1939 methyltransferase from Escherichia coli.

  The Journal of biological chemistry 20020315

• Dual function of the tRNA(m(5)U54)methyltransferase in tRNA maturation.

  RNA (New York, N.Y.) 20020301

• Synthesis of novel 3'-C-methylene thymidine and 5-methyluridine/cytidine H-phosphonates and phosphonamidites for new backbone modification of oligonucleotides.

  The Journal of organic chemistry 20010420

• Characterization of mouse and human monoclonal antibodies cross-reactive with SLE serum antibodies to guanosine.

  Journal of immunology (Baltimore, Md. : 1950) 19840601