146346-82-9 | Fmoc-thr(tbdms)-oh

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$25.00	$18.00
1g	95%	in stock	$71.00	$50.00
5g	95%	in stock	$254.00	$178.00
10g	95%	in stock	$369.00	$259.00
25g	95%	in stock	$738.00	$517.00

Description

• Catalog Number: AA64514
• Chemical Name: Fmoc-thr(tbdms)-oh
• CAS Number: 146346-82-9
• Molecular Formula: C25H33NO5Si
• Molecular Weight: 455.6187
• MDL Number: MFCD02092976
• SMILES: O=C(N[C@@H]([C@H](O[Si](C(C)(C)C)(C)C)C)C(=O)O)OCC1c2ccccc2-c2c1cccc2

Upstream Synthesis Route

Fmoc-Thr(TBDMS)-OH is a versatile building block commonly used in chemical synthesis due to its ability to introduce the threonine amino acid into peptide and organic molecule structures. Threonine is a vital component of many biologically active peptides and proteins, making this reagent essential in the development of pharmaceuticals, bioconjugates, and peptide-based materials. As part of the Fmoc (9-fluorenylmethoxycarbonyl) strategy for solid-phase peptide synthesis, Fmoc-Thr(TBDMS)-OH enables selective peptide bond formation, protecting the threonine amino acid from unwanted side reactions. The tert-butyldimethylsilyl (TBDMS) protecting group offers stability during various synthetic steps while also being readily removable under mild conditions. With its efficient and reliable performance, Fmoc-Thr(TBDMS)-OH is a valuable tool in the construction of complex peptide sequences with high purity and yield.