146549-21-5 | Fmoc-L-allylglycine

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$8.00	$5.00
1g	97%	in stock	$18.00	$12.00
5g	97%	in stock	$71.00	$50.00
10g	97%	in stock	$140.00	$98.00
25g	97%	in stock	$349.00	$244.00

Description

• Catalog Number: AA64742
• Chemical Name: Fmoc-L-allylglycine
• CAS Number: 146549-21-5
• Molecular Formula: C20H19NO4
• Molecular Weight: 337.3692
• MDL Number: MFCD01311749
• SMILES: C=CC[C@@H](C(=O)O)NC(=O)OCC1c2ccccc2-c2c1cccc2

Computed Properties

• Complexity: 484
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 25
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 7
• XLogP3: 3.8

Upstream Synthesis Route

Fmoc-Gly(allyl)-OH, also known as Fmoc-Glycine(allyl) alcohol, is a key building block in chemical synthesis, particularly in solid-phase peptide synthesis (SPPS) and the production of peptide libraries. This compound serves as a versatile tool for introducing glycine residues within peptide sequences due to its Fmoc-protected amine group and allyl side chain functionalities. The Fmoc protection group can be selectively removed under mild basic conditions, allowing for further peptide elongation reactions, while the allyl group enables efficient side chain manipulations and conjugation strategies. Additionally, the hydroxyl group provides flexibility for further modifications, making Fmoc-Gly(allyl)-OH a valuable component in the synthesis of complex peptides and peptidomimetics with tailored properties and functionalities.