147-24-0 | N-(2-Diphenylmethoxyethyl)-N,N-Dimethylamine Hydrochloride

Packsize	Purity	Availability	Price	Discounted Price
5g	95%	in stock	$25.00	$18.00
25g	95%	in stock	$42.00	$30.00
100g	95%	in stock	$90.00	$63.00
250g	95%	in stock	$155.00	$108.00
500g	95%	in stock	$251.00	$176.00
1kg	95%	in stock	$498.00	$348.00

Description

• Catalog Number: AB76390
• Chemical Name: N-(2-Diphenylmethoxyethyl)-N,N-Dimethylamine Hydrochloride
• CAS Number: 147-24-0
• Molecular Formula: C17H22ClNO
• Molecular Weight: 291.8157
• MDL Number: MFCD00012479
• SMILES: CN(CCOC(c1ccccc1)c1ccccc1)C.Cl

Computed Properties

• Complexity: 211
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 6

Literature

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  The western journal of emergency medicine 20141101

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• Transfer of wastewater associated pharmaceuticals and personal care products to crop plants from biosolids treated soil.

  Ecotoxicology and environmental safety 20121101

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• Removal of diphenhydramine from water by swelling clay minerals.

  Journal of colloid and interface science 20110801

• Anaphylaxis from depot medroxyprogesterone acetate in an adolescent girl.

  Obstetrics and gynecology 20110801

• Diphenhydramine overdose mimicking serotonin syndrome.

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• Motion sickness: comparison of metoclopramide and diphenhydramine to placebo.

  Prehospital and disaster medicine 20110801

• RN administered 125 mg of benadryl to two-year-old. Case on point: K. D. v. Adrianne Chambers, RN, 49A04-1010-CT-636 (7/13/2011)-IN.

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  Journal of medical toxicology : official journal of the American College of Medical Toxicology 20110601

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• The case of the horrible hives.

  ONS connect 20110501

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  Pediatrics 20110401

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  Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20110301

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  Talanta 20110215

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• Mast cells are critical for protection against peptic ulcers induced by the NSAID piroxicam.

  PloS one 20110101

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  Journal of psychopharmacology (Oxford, England) 20090101

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  Advances in therapy 20090101

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• Fatal diphenhydramine poisoning with increased vascular permeability including late pulmonary congestion refractory to percutaneous cardiovascular support.

  Clinical toxicology (Philadelphia, Pa.) 20081101

• A prospective, randomized, double-blind controlled trial of acetaminophen and diphenhydramine pretransfusion medication versus placebo for the prevention of transfusion reactions.

  Transfusion 20081101

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  Transfusion 20081101

• Anaphylaxis caused by tangerine seeds but not tangerine fruit.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20081101

• Biphasic effects of orexin-A on autonomic nerve activity and lipolysis.

  Neuroscience letters 20081024

• WITHDRAWN: Symptomatic treatment of the cough in whooping cough.

  The Cochrane database of systematic reviews 20081008

• A randomized controlled trial of prochlorperazine versus metoclopramide for treatment of acute migraine.

  Annals of emergency medicine 20081001

• I'm 75, and I've always taken Benadryl for my allergies. My doctor advised me to switch to a prescription allergy medication. Why?

  The Johns Hopkins medical letter health after 50 20081001

• Sleep complaints: Whenever possible, avoid the use of sleeping pills.

  Prescrire international 20081001

• The preventive effect of diphenhydramine on bacterial growth in propofol: a laboratory study.

  European journal of anaesthesiology 20080901

• Specific interactions between diphenhydramine and alpha-helical poly(glutamic acid)--a new ion-pairing complex for taste masking and pH-controlled diphenhydramine release.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080901

• Effect of a pharmaceutical cationic exchange resin on the properties of controlled release diphenhydramine hydrochloride matrices using Methocel K4M or Ethocel 7cP as matrix formers.

  AAPS PharmSciTech 20080901

• Can in vitro metabolism-dependent covalent binding data in liver microsomes distinguish hepatotoxic from nonhepatotoxic drugs? An analysis of 18 drugs with consideration of intrinsic clearance and daily dose.

  Chemical research in toxicology 20080901

• An algorithm for treatment of patients with hypersensitivity reactions after vaccines.

  Pediatrics 20080901

• Cardiotoxicity after massive amantadine overdose.

  Journal of medical toxicology : official journal of the American College of Medical Toxicology 20080901

• Regulation of sympathetic nerve activity by L-carnosine in mammalian white adipose tissue.

  Neuroscience letters 20080815

• 'I am flying to the stars'--suicide by aircraft in Germany.

  Forensic science international 20080806

• Morphine, opioids, and the feline pulmonary vascular bed.

  Acta anaesthesiologica Scandinavica 20080801

• Frequency, outcome, and appropriateness of treatment of nonionic iodinated contrast media reactions.

  AJR. American journal of roentgenology 20080801

• Concomitant allergic contact dermatitis from diphenhydramine and metronidazole.

  Contact dermatitis 20080801

• Confusion and stroke due to an 'umbrella brand' product.

  Prescrire international 20080801

• Hypaphorine, an indole alkaloid from Erythrina velutina, induced sleep on normal mice.

  Bioorganic & medicinal chemistry letters 20080715

• Cocaine-like neurochemical effects of antihistaminic medications.

  Journal of neurochemistry 20080701

• Brain histamine H1 receptor occupancy of orally administered antihistamines, bepotastine and diphenhydramine, measured by PET with 11C-doxepin.

  British journal of clinical pharmacology 20080601

• Peanut and tree nut allergy in childhood.

  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20080601

• Taste mask, design and evaluation of an oral formulation using ion exchange resin as drug carrier.

  AAPS PharmSciTech 20080601

• Noncardiogenic pulmonary edema in a patient receiving vancomycin and oxycodone-acetaminophen.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20080601

• Identification of histamine receptors and reduction of squalene levels by an antihistamine in sebocytes.

  The Journal of investigative dermatology 20080501

• Acute generalized bullous eruption in a 2-year-old boy.

  Archives of dermatology 20080501

• Time-dependent inhibition of histamine-induced cutaneous responses by oral and intramuscular diphenhydramine and oral fexofenadine.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20080501

• Histamine-induced modulation of vascular tone in the isolated chicken basilar artery: a possible involvement of endothelium.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20080401

• Vagal hypertonia and anesthesia in Angelman syndrome.

  Paediatric anaesthesia 20080401

• Effects of 2-week treatment with temazepam and diphenhydramine in elderly insomniacs: a randomized, placebo-controlled trial.

  Journal of clinical psychopharmacology 20080401

• Selective determination of diphenhydramine in compound pharmaceutical containing ephedrine by flow-injection electrochemiluminescence.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20080401

• Successful amelioration of oxaliplatin-induced hyperexcitability syndrome with the antiepileptic pregabalin in a patient with pancreatic cancer.

  Cancer chemotherapy and pharmacology 20080301

• Antihistamine mepyramine directly inhibits KCNQ/M channel and depolarizes rat superior cervical ganglion neurons.

  Neuropharmacology 20080301

• Successful management of difficult infusion-associated reactions in a young patient with mucopolysaccharidosis type VI receiving recombinant human arylsulfatase B (galsulfase [Naglazyme]).

  Pediatrics 20080301

• [Anticholinergic syndrome. A case report].

  Revista clinica espanola 20080301

• Systemic vs. central administration of common hypnotics reveals opposing effects on genioglossus muscle activity in rats.

  Sleep 20080301

• A serum sickness-like reaction to a commonly used acne drug.

  JAAPA : official journal of the American Academy of Physician Assistants 20080301

• Carnosine protects against Abeta42-induced neurotoxicity in differentiated rat PC12 cells.

  Cellular and molecular neurobiology 20080201

• Paradoxical excitation on diphenhydramine may be associated with being a CYP2D6 ultrarapid metabolizer: three case reports.

  CNS spectrums 20080201

• Rare complications of diphenhydramine toxicity.

  Connecticut medicine 20080201

• Painful sores in a young boy's mouth. Herpetic stomatitis.

  JAAPA : official journal of the American Academy of Physician Assistants 20080201

• Spectrophotometric determination of some histamine H1-antagonists drugs in their pharmaceutical preparations.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080101

• Paclitaxel and gemcitabine versus carboplatin and gemcitabine in patients with advanced non-small-cell lung cancer. A phase III study of the Hellenic Cooperative Oncology Group.

  Annals of oncology : official journal of the European Society for Medical Oncology 20080101

• Effect of diphenhydramine on myocardial injury caused by organophosphate poisoning.

  Clinical toxicology (Philadelphia, Pa.) 20080101

• Lorazepam, diphenhydramine, and haloperidol transdermal gel for rescue from chemotherapy-induced nausea/vomiting: results of two pilot trials.

  The journal of supportive oncology 20080101

• Cholinergic responses of ileal longitudinal muscle under short-lasting exposure to cupric ions.

  Autonomic & autacoid pharmacology 20080101

• Comparison of diphenhydramine and nonsedating antihistamines for the treatment of acute allergic reactions.

  Allergy and asthma proceedings 20080101

• Acute dystonic reaction associated with foscarnet administration.

  American journal of therapeutics 20080101

• Over-the-counter cough and cold medication use in young children.

  Pediatric nursing 20080101

• Efficacy of a scheduled IV cocktail of antiemetics for the palliation of nausea and vomiting in a hospice population.

  The American journal of hospice & palliative care 20080101

• PAF, rather than histamine, participates in mouse anaphylactic hypotension.

  Pharmacology 20080101

• Emedastine difumarate inhibits histamine-induced collagen synthesis in dermal fibroblasts.

  Journal of investigational allergology & clinical immunology 20080101

• Which medications are safe and effective for improving sleep at high altitude?

  High altitude medicine & biology 20080101

• Extrapyramidal syndrome presenting as dysphagia: a case report.

  The American journal of hospice & palliative care 20080101

• Hair analysis for diphenhydramine after surreptitious administration to a child.

  Forensic science international 20071220

• Efficacy of diphenhydramine against cough in humans: a review.

  Pharmacy world & science : PWS 20071201

• The comparison of diphenhydramine HCl and Nedocromil sodium in prevention of abdominal postoperative adhesion formation in rat models: an experimental study.

  International journal of surgery (London, England) 20071201

• Comparison of the effectiveness of amitriptyline and gabapentin on chronic neuropathic pain in persons with spinal cord injury.

  Archives of physical medicine and rehabilitation 20071201

• What's eating you? Pigeon mite (Dermanyssus gallinae).

  Cutis 20071201

• Radiocontrast-induced anaphylaxis despite pretreatment and use of iso-osmolar contrast.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20071101

• Methadone toxicity fatalities: a review of medical examiner cases in a large metropolitan area.

  Journal of forensic sciences 20071101

• [Treatment of acute respiratory infections among service-men].

  Voenno-meditsinskii zhurnal 20071101

• Enhancement of iontophoretic transport of diphenhydramine hydrochloride thermosensitive gel by optimization of pH, polymer concentration, electrode design, and pulse rate.

  AAPS PharmSciTech 20071001

• Stabilized hemocompatible coating of nitinol devices based on photo-cross-linked alginate/heparin multilayer.

  Langmuir : the ACS journal of surfaces and colloids 20070828

• Comparison of diphenhydramine and modafinil on arousal and autonomic functions in healthy volunteers.

  Journal of psychopharmacology (Oxford, England) 20070801

• The use of microdialysis for the study of drug kinetics: central nervous system pharmacokinetics of diphenhydramine in fetal, newborn, and adult sheep.

  Drug metabolism and disposition: the biological fate of chemicals 20070801

• Midazolam vs. diphenhydramine for the treatment of metoclopramide-induced akathisia: a randomized controlled trial.

  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20070801

• Is acetaminophen as effective as an antihistamine-decongestant-acetaminophen combination in relieving symptoms of acute nasopharyngitis in children? A randomised, controlled trial.

  International journal of pediatric otorhinolaryngology 20070801

• Anaphylaxis to piperacillin-tazobactam despite a negative penicillin skin test.

  Allergy 20070801

• Preliminary experience with a modified premedication protocol that included intravenous diphenhydramine and calcium bromide for the prophylaxis of paclitaxel-related hypersensitivity reactions.

  International journal of clinical oncology 20070801

• Development and validation of a liquid chromatography/tandem mass spectrometry assay for the simultaneous determination of D-amphetamine and diphenhydramine in beagle dog plasma and its application to a pharmacokinetic study.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070701

• Bacampicillin uptake is shared with thiamine in Caco-2 cells.

  Biological & pharmaceutical bulletin 20070701

• [A phase II study of weekly paclitaxel for advanced or recurrent breast cancer].

  Gan to kagaku ryoho. Cancer & chemotherapy 20070701

• Implications of diphenhydramine single-dose unintended ingestions in young children.

  Pediatric emergency care 20070701

• Manufacture of fine spherical granules by an extrusion/spheronization method.

  International journal of pharmaceutics 20070607

• A 6-month old with total body flushing and a macular-papular lesion.

  Pediatric emergency care 20070501

• First-generation H1 antihistamines found in pilot fatalities of civil aviation accidents, 1990-2005.

  Aviation, space, and environmental medicine 20070501

• FDA halts sales of some anti-vomiting suppositories...and are cough medications effective in children?

  Child health alert 20070501

• Potential aripiprazole-mediated extrapyramidal symptoms in an adult with developmental disabilities.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070415

• In vivo effects of leptin on autonomic nerve activity and lipolysis in rats.

  Neuroscience letters 20070412

• Serotonin syndrome.

  Emergency medicine journal : EMJ 20070401

• Study on the antinociceptive action of Tyr-K-MIF-1, a peptide from the MIF family.

  Autonomic & autacoid pharmacology 20070401

• Fingerprint analysis and synthetic adulterant search in Hedera helix formulations by capillary electrophoresis.

  Die Pharmazie 20070401

• [Diphenhydramine poisoning presented with psychotic-like symptoms and choreic involuntary movement: report of two cases].

  Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology 20070401

• [Two cases of diphenhydramine related suicide].

  Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology 20070401

• Action of anti-tussive drugs on the emetic reflex of Suncus murinus (house musk shrew).

  European journal of pharmacology 20070322

• Safety and efficacy of a continuous infusion, patient-controlled antiemetic pump for children receiving emetogenic chemotherapy.

  Pediatric blood & cancer 20070301

• Comparison of diphenhydramine and lidocaine for prevention of pain after injection of propofol: a double-blind, placebo-controlled, randomized study.

  European journal of anaesthesiology 20070301

• Vitreous injections of pegaptanib sodium triggering allergic reactions.

  American journal of ophthalmology 20070301

• Influences of histamine H1 receptor antagonists on maximal electroshock seizure in infant rats.

  Biological & pharmaceutical bulletin 20070301

• [Reversing effect of histamine on neurotoxicity induced by beta-amyloid1-42].

  Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20070301

• [Determination of ambroxol and clenbuterol in human plasma by LC-MS/MS method].

  Yao xue xue bao = Acta pharmaceutica Sinica 20070301

• [Direct determination of four components in compound paracetamol and diphenhydramine tablets by wide bore capillary gas chromatography].

  Se pu = Chinese journal of chromatography 20070301

• Cross-reactivity between paclitaxel and hazelnut: a case report.

  Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20070301

• Self-administration of cocaine-antihistamine combinations: super-additive reinforcing effects.

  European journal of pharmacology 20070227

• Induction of keratinocyte apoptosis by photosensitizing chemicals plus UVA.

  Journal of dermatological science 20070201

• Effects of some H1-antagonists on the sleep-wake cycle in sleep-disturbed rats.

  Journal of pharmacological sciences 20070201

• How much is too much? Oligosymptomatic presentation after 11.5 g of diphenhydramine.

  Human & experimental toxicology 20070201

• Ginkgo biloba extract improves spatial memory in rats mainly but not exclusively via a histaminergic mechanism.

  Brain research 20070119

• A new hydrophilic interaction liquid chromatographic (HILIC) procedure for the simultaneous determination of pseudoephedrine hydrochloride (PSH), diphenhydramine hydrochloride (DPH) and dextromethorphan hydrobromide (DXH) in cough-cold formulations.

  Journal of pharmaceutical and biomedical analysis 20070104

• Identification of human cytochrome p450 isozymes involved in diphenhydramine N-demethylation.

  Drug metabolism and disposition: the biological fate of chemicals 20070101

• Acetaminophen and diphenhydramine premedication for allergic and febrile nonhemolytic transfusion reactions: good prophylaxis or bad practice?

  Transfusion medicine reviews 20070101

• Diphenhydramine in infants.

  Archives of pediatrics & adolescent medicine 20070101

• [Recent and potential drugs for treatment of insomnia].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20070101

• Apparent anaphylactoid reaction after treatment with a single dose of telithromycin.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20070101

• [Diphenhydramine does not help the poor sleeper].

  Medizinische Monatsschrift fur Pharmazeuten 20070101

• Hemodynamic effects of nesiritide and dopamine in cardiovascular collapse assessed via impedance cardiography.

  Congestive heart failure (Greenwich, Conn.) 20070101

• Dyskinesias associated with atomoxetine in combination with other psychoactive drugs.

  Clinical toxicology (Philadelphia, Pa.) 20070101

• First-generation antihistamines diphenhydramine and chlorpheniramine reverse cytokine-afforded eosinophil survival by enhancing apoptosis.

  Allergy and asthma proceedings 20070101

• Evaluation of the guinea pig monophasic action potential (MAP) assay in predicting drug-induced delay of ventricular repolarisation using 12 clinically documented drugs.

  Journal of pharmacological and toxicological methods 20070101

• Histamine induces the expression of uncoupling protein 2 (UCP2) and acid-binding protein (aP2) in white adipocytes.

  Clinical chemistry and laboratory medicine 20070101

• Diphenhydramine versus nonsedating antihistamines for acute allergic reactions: a literature review.

  Allergy and asthma proceedings 20070101

• Synthesis of some substituted pyrazinopyridoindoles and 3D QSAR studies along with related compounds: piperazines, piperidines, pyrazinoisoquinolines, and diphenhydramine, and its semi-rigid analogs as antihistamines (H1).

  Bioorganic & medicinal chemistry 20061215

• Effect of levofloxacin on serum glucose concentration in rats.

  European journal of pharmacology 20061203

• [Effects of Caulis Sinomenii and sinomenine on morphine-induced place preference and brain histamine level in mice].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20061201

• Erythema multiforme after meningitis vaccine: patient safety concerns with repeat immunization.

  Pharmacotherapy 20061101

• A case of metoclopramide-induced oculogyric crisis in a 16-year-old girl with cystic fibrosis.

  Southern medical journal 20061101

• The benzodiazepine alprazolam dissociates contextual fear from cued fear in humans as assessed by fear-potentiated startle.

  Biological psychiatry 20061001

• Poisonings with diphenhydramine--a survey of 68 clinical and 55 death cases.

  Forensic science international 20060912

• Exposure to alcohol-containing medications during pregnancy.

  Canadian family physician Medecin de famille canadien 20060910

• Successful desensitization to antithymocyte globulin in a child with aplastic anemia.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20060901

• Child assessment of dextromethorphan, diphenhydramine, and placebo for nocturnal cough due to upper respiratory infection.

  Clinical pediatrics 20060901

• [Effect of histamine on intracortical blood vessels of rats].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20060901

• Benadryl for infant sleep?

  Child health alert 20060901

• Ciprofloxacin-induced anaphylactoid reaction.

  European journal of pediatrics 20060801

• Heparin reverses anaphylactoid shock in a porcine model.

  Annals of emergency medicine 20060801

• Sensitivity of late-latency auditory and somatosensory evoked potentials to threat of electric shock and the sedative drugs diazepam and diphenhydramine in human volunteers.

  Journal of psychopharmacology (Oxford, England) 20060701

• Successful retreatment with infliximab in patients with prior severe infusion reactions.

  Clinical rheumatology 20060701

• Sedation and memory: studies with a histamine H-1 receptor antagonist.

  Journal of psychopharmacology (Oxford, England) 20060701

• Adverse extrapyramidal effects in four horse given fluphenazine decanoate.

  Journal of the American Veterinary Medical Association 20060701

• The trial of infant response to diphenhydramine: the TIRED study--a randomized, controlled, patient-oriented trial.

  Archives of pediatrics & adolescent medicine 20060701

• Diphenhydramine vs desloratadine comparisons must consider risk-benefit ratio.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060701

• Emergency department treatment of anaphylaxis: is epinephrine always indicated?

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060701

• Characterizing impaired functional alertness from diphenhydramine in the elderly with performance and neurophysiologic measures.

  Sleep 20060701

• [Determination of risperidone in human plasma by liquid chromatography-tandem mass spectrometry].

  Yao xue xue bao = Acta pharmaceutica Sinica 20060701

• Study of overload for basic compounds in reversed-phase high performance liquid chromatography as a function of mobile phase pH.

  Journal of chromatography. A 20060630

• Quantitative analysis of liquid formulations using FT-Raman spectroscopy and HPLC The case of diphenhydramine hydrochloride in Benadryl.

  Journal of pharmaceutical and biomedical analysis 20060616

• A pharmacokinetic study of diphenhydramine transport across the blood-brain barrier in adult sheep: potential involvement of a carrier-mediated mechanism.

  Drug metabolism and disposition: the biological fate of chemicals 20060601

• Oral sedation with midazolam and diphenhydramine compared with midazolam alone in children undergoing magnetic resonance imaging.

  Paediatric anaesthesia 20060601

• Relationship between sedation and pupillary function: comparison of diazepam and diphenhydramine.

  British journal of clinical pharmacology 20060601

• A clinical trial of trimethobenzamide/diphenhydramine versus sumatriptan for acute migraines.

  Headache 20060601

• Application and validation of chemometrics-assisted spectrophotometry and liquid chromatography for the simultaneous determination of six-component pharmaceuticals.

  Journal of pharmaceutical and biomedical analysis 20060503

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• H(1)- antihistamines and activated blood platelets.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060401

• Fluphenazine-induced extrapyramidal side effects in a horse.

  The Veterinary clinics of North America. Equine practice 20060401

• Preparation and in vitro release of dual-drug resinates containing equivalent content dextromethorphan and diphenhydramine.

  Drug development and industrial pharmacy 20060401

• Management of primary herpetic gingivostomatitis in young children.

  Pediatric emergency care 20060401

• Efficacy of diphenhydramine vs desloratadine and placebo in patients with moderate-to-severe seasonal allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060401

• [H2 receptor mediates the protective effect of histamine against the cellular edema and viability reduction induced by oxygen-glucose deprivation in rat hippocampal slices].

  Yao xue xue bao = Acta pharmaceutica Sinica 20060401

• The effects of sufentanil in the feline pulmonary vascular bed.

  European journal of pharmacology 20060318

• Fatality from diphenhydramine monointoxication: a case report and review of the infant, pediatric, and adult literature.

  The American journal of forensic medicine and pathology 20060301

• Intravenous administration of diphenhydramine reduces histamine-induced vasodilator effects in the retina and choroid.

  Investigative ophthalmology & visual science 20060301

• Red, itchy eyes, giant papillae.

  Advance for nurse practitioners 20060301

• Acupuncture plus point-injection for 32 cases of obstinate urticaria.

  Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 20060301

• Diphenhydramine as an adjunct to sedation for colonoscopy: a double-blind randomized, placebo-controlled study.

  Gastrointestinal endoscopy 20060101

• Structural and functional comparison of mast cells in the pregnant versus nonpregnant human uterus.

  American journal of obstetrics and gynecology 20060101

• [Perioperative management of a patient allergic to multiple nondepolarizing neuromuscular blockers during treatment for cervical fracture and dislocation].

  Revista espanola de anestesiologia y reanimacion 20060101

• Effects of diphenhydramine and famotidine on lipid peroxidation and activities of antioxidant enzymes in different rat tissues.

  Pharmacological reports : PR 20060101

• Diphenhydramine and dimenhydrinate poisoning: an evidence-based consensus guideline for out-of-hospital management.

  Clinical toxicology (Philadelphia, Pa.) 20060101

• [Use of microcolon gradient high performance liquid chromatography for urine dimedrol assay in combined poisoning].

  Sudebno-meditsinskaia ekspertiza 20060101

• The use of sleep aids among Emergency Medicine residents: a web based survey.

  BMC health services research 20060101

• Analysis of the effects of fentanyl in the feline pulmonary vascular bed.

  American journal of therapeutics 20060101

• OTC product: Theraflu Thin Strips.

  Journal of the American Pharmacists Association : JAPhA 20060101

• Acute hypersensitivity reaction to ferric gluconate in a premedicated patient.

  The Annals of pharmacotherapy 20051201

• Topiramate in chronic lumbar radicular pain.

  The journal of pain : official journal of the American Pain Society 20051201

• Tolerability of the compound ABHR in hospice patients.

  Journal of palliative medicine 20051201

• Survey of topical oral solutions for the treatment of chemo-induced oral mucositis.

  Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20051201

• Anaphylactoid reaction after verteporfin therapy.

  American journal of ophthalmology 20051101

• Parenteral iron therapy: a single institution's experience over a 5-year period.

  Journal of the National Comprehensive Cancer Network : JNCCN 20051101

• Valerian-hops combination and diphenhydramine for treating insomnia: a randomized placebo-controlled clinical trial.

  Sleep 20051101

• Standing orders for allergy symptoms and anaphylaxis in the K through 12 school setting.

  School nurse news 20051101

• A trial of metoclopramide vs sumatriptan for the emergency department treatment of migraines.

  Neurology 20051025

• A trial of metoclopramide vs sumatriptan for the emergency department treatment of migraines.

  Neurology 20051025

• Structural basis for inhibition of histamine N-methyltransferase by diverse drugs.

  Journal of molecular biology 20051021

• Olfactory stimulation with scent of essential oil of grapefruit affects autonomic neurotransmission and blood pressure.

  Brain research 20051005

• Self-management and pregnancy--safe interventions for panic, phobia and other anxiety-disorders might include over-the-counter (OTC) 'SSRI' antihistamines such as diphenhydramine and chlorpheniramine.

  Acta psychiatrica Scandinavica 20051001

• Anaphylactoid reaction after retrograde pyelography despite preoperative steroid preparation.

  Urology 20051001

• Cold urticaria: a case report and review of the literature.

  Cutis 20051001

• Separation and determination of pseudoephedrine, dextromethorphan, diphenhydramine and chlorpheniramine in cold medicines by nonaqueous capillary electrophoresis.

  Journal of pharmaceutical and biomedical analysis 20050901

• Premedication with acetaminophen or diphenhydramine for transfusion with leucoreduced blood products in children.

  British journal of haematology 20050901

• Some advantages of high temperature for the separation of pharmaceutical compounds with mass spectrometry detection.

  Journal of separation science 20050901

• The perils of peanuts.

  School nurse news 20050901

• Diphenhydramine overdose and Brugada sign.

  Pacing and clinical electrophysiology : PACE 20050701

• Modulation of metoprolol pharmacokinetics and hemodynamics by diphenhydramine coadministration during exercise testing in healthy premenopausal women.

  The Journal of pharmacology and experimental therapeutics 20050601

• Antiemetic and analgesic-sparing effects of diphenhydramine added to morphine intravenous patient-controlled analgesia.

  British journal of anaesthesia 20050601

• The effect of morphine in rat small mesenteric arteries.

  Vascular pharmacology 20050601

• Tapering and discontinuation of glucocorticoid prophylaxis during prolonged weekly to biweekly paclitaxel administration.

  Chemotherapy 20050501

• Comparison of colchicine, dapsone, triamcinolone, and diphenhydramine therapy for the treatment of brown recluse spider envenomation: a double-blind, controlled study in a rabbit model.

  Archives of dermatology 20050501

• Effects of calcineurin inhibitors on an in vitro assay for chronic urticaria.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20050501

• A pilot study of weekly paclitaxel administration for patients with relapsed cervical cancer after heavy medication.

  Gan to kagaku ryoho. Cancer & chemotherapy 20050501

• Treatment for methaqualone dependence in adults.

  The Cochrane database of systematic reviews 20050418

• Microemulsions as colloidal vehicle systems for dermal drug delivery. Part V: Microemulsions without and with glycolipid as penetration enhancer.

  Journal of pharmaceutical sciences 20050401

• Diphenhydramine in the treatment of akathesia induced by prochlorperazine.

  The Journal of emergency medicine 20050401

• Evaluation of diphenhydramine as a sedative for dogs.

  Journal of the American Veterinary Medical Association 20050401

• [Effect of Ginkgo biloba extract on memory deficits in radial maze performance induced by some drugs in rats].

  Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20050401

• Prolonged QT interval with markedly abnormal ventricular repolarization in diphenhydramine overdose.

  International journal of cardiology 20050318

• Brown recluse spider bites: a complex problem wound. A brief review and case study.

  Ostomy/wound management 20050301

• More on sleeping pills.

  Harvard health letter 20050301

• Involvement of CGRP in the inhibitory effect of rutaecarpine on vasoconstriction induced by anaphylaxis in guinea pig.

  Regulatory peptides 20050215

• QT interval prolongation in diphenhydramine toxicity.

  International journal of cardiology 20050215

• A trial of metoclopramide vs sumatriptan for the emergency department treatment of migraines.

  Neurology 20050208

• Efficacy of intravenous diphenhydramine versus intravenous DHE-45 in the treatment of severe migraine headache.

  Current pain and headache reports 20050201

• Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.

  Pediatrics 20050201

• Pharmacokinetic effects of diphenhydramine or oxycodone in simulated acetaminophen overdose.

  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20050201

• Evaluation of the anti-emetic potential of anti-migraine drugs to prevent resiniferatoxin-induced emesis in Suncus murinus (house musk shrew).

  European journal of pharmacology 20050131

• Imaging of the corpus striatum without any activity at 192 MBq 18F-fluorodeoxyglucose PET after intoxication.

  European journal of nuclear medicine and molecular imaging 20050101

• Allosteric modulation of GABA(B) receptor function in human frontal cortex.

  Neurochemistry international 20050101

• Development and validation of a capillary electrophoresis method for the determination of codeine, diphenhydramine, ephedrine and noscapine in pharmaceuticals.

  Farmaco (Societa chimica italiana : 1989) 20050101

• Allergic contact dermatitis presenting in the emergency department.

  Contact dermatitis 20050101

• Reversible opsoclonus after diphenhydramine misuse.

  European neurology 20050101

• Approach to therapy in chronic urticaria: when benadryl is not enough.

  Allergy and asthma proceedings 20050101

• Kids' cough drugs may not work.

  Consumer reports 20041201

• Over-the-counter cough and cold medicines: should parents be using them for their children?

  The Annals of pharmacotherapy 20041101

• Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.

  Pediatrics 20041101

• Reactions of 2 young children with milk allergy after cutaneous exposure to milk-containing cosmetic products.

  Archives of pediatrics & adolescent medicine 20041101

• On call: I am a 71-year-old man with diabetes and high blood pressure. Ever since I can remember, I've been bothered by painful canker sores two or three times a year. My doctor says they aren't caused by my medication and I think he's right, since the cankers started before I developed diabetes. What causes the sores, and what can I do about them?

  Harvard men's health watch 20041101

• [Diphenhydramin-overdose: anticholinergic symptoms, EEG-findings in the course and drug treatment of a gerontopsychiatric patient].

  Psychiatrische Praxis 20041101

• Pharmacologic management of behavioral instability in medically ill pediatric patients.

  Current opinion in pediatrics 20041001

• Infusion-related reactions to infliximab in patients with rheumatoid arthritis in a clinical practice setting: relationship to dose, antihistamine pretreatment, and infusion number.

  The Journal of rheumatology 20041001

• Appropriate use of epinephrine in anaphylaxis.

  The American journal of emergency medicine 20041001

• Diphenhydramine-associated wide complex dysrhythmia.

  The American journal of emergency medicine 20041001

• Do over-the-counter cough remedies work?

  Child health alert 20041001

• The histaminergic system of the brain: its roles in arousal and autonomic regulation.

  Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20041001

• Preliminary report of the discovery of a new pharmaceutical granulation process using foamed aqueous binders.

  Drug development and industrial pharmacy 20040901

• Oral benadryl and central venous catheter abuse-a potentially 'lethal combination'.

  Pediatric emergency care 20040901

• Effects of desloratadine, diphenhydramine, and placebo on driving performance and psychomotor performance measurements.

  European journal of clinical pharmacology 20040701

• Hypersensitivity reactions to oxaliplatin: a case report and the success of a continuous infusional desensitization schedule.

  Anti-cancer drugs 20040701

• Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.

  Pediatrics 20040701

• A strategy to decrease the use of risky drugs in the elderly.

  Cleveland Clinic journal of medicine 20040701

• Identification of diphenhydramine metabolites in human urine by capillary electrophoresis-ion trap-mass spectrometry.

  Electrophoresis 20040601

• Over-the-counter topical antipruritic agents are commonly recommended by office-based physicians: an analysis of US practice patterns.

  The Journal of dermatological treatment 20040601

• [Usefulness of weekly administration of paclitaxel for advanced or recurrent gastric cancer].

  Gan to kagaku ryoho. Cancer & chemotherapy 20040601

• Challenges in palliative care research: one experience.

  Journal of palliative medicine 20040601

• Urinary retention following repeated high-dose quetiapine.

  The Annals of pharmacotherapy 20040501

• Methadone mouthwash for the management of oral ulcer pain.

  Journal of pain and symptom management 20040501

• Reversal of an antihistamine-induced coma with flumazenil.

  Pediatric emergency care 20040501

• Case of polymorphic ventricular tachycardia in diphenhydramine poisoning.

  Journal of cardiovascular electrophysiology 20040501

• Desloratadine shows no effect on performance during 6 h at 8,000 ft simulated cabin altitude.

  Aviation, space, and environmental medicine 20040501

• Simultaneous determination of chlorpheniramine and pseudoephedrine in human plasma by liquid chromatography-tandem mass spectrometry.

  Biomedical chromatography : BMC 20040501

• Influence of histamine and H1-receptor antagonists on ejaculated human spermatozoa: role of intrasperm Ca2+.

  Indian journal of experimental biology 20040501

• Diphenhydramine in the treatment of akathisia induced by prochlorperazine.

  The Journal of emergency medicine 20040401

• Atypical laryngeal dystonia caused by an antiemetic.

  American family physician 20040401

• [Paclitaxel plus carboplatin in ovarian cancer-comparison of adverse effects between monthly and weekly administration].

  Gan to kagaku ryoho. Cancer & chemotherapy 20040401

• Role of histamine and acid back-diffusion in modulation of gastric microvascular permeability and hemorrhagic ulcers in Salmonella typhimurium-infected rats.

  Life sciences 20040305

• Abuse liability and stimulant properties of dextromethorphan and diphenhydramine combinations in rats.

  Psychopharmacology 20040301

• Combination of LC/TOF-MS and LC/Ion trap MS/MS for the identification of diphenhydramine in sediment samples.

  Analytical chemistry 20040301

• Can we improve the assessment of discharge readiness?: A comparative study of observational and objective measures of depth of sedation in children.

  Anesthesiology 20040201

• Acute delirium associated with combined diphenhydramine and linezolid use.

  The Annals of pharmacotherapy 20040101

• Diphenhydramine gargling may slow the healing of oral lesions of pemphigus vulgaris.

  Journal of drugs in dermatology : JDD 20040101

• Haloperidol impairs learning and error-related negativity in humans.

  Journal of cognitive neuroscience 20040101

• Apoptosis of human T-cell acute lymphoblastic leukemia cells by diphenhydramine, an H1 histamine receptor antagonist.

  Oncology research 20040101

• Effects of histamine receptor blockade on cardiovascular changes induced by 35 GHz radio frequency radiation heating.

  Autonomic & autacoid pharmacology 20040101

• Maternal exposure to diphenhydramine during the fetal period in rats: effects on physical and neurobehavioral development and on neurochemical parameters.

  Neurotoxicology and teratology 20040101

• A phase II evaluation of weekly paclitaxel plus carboplatin in advanced urothelial cancer.

  Cancer investigation 20040101

• Pulmonary inflammation and thrombogenicity caused by diesel particles in hamsters: role of histamine.

  American journal of respiratory and critical care medicine 20031201

• Anaphylaxis treatment: the details.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20031125

• Epileptogenic activity induced by histamine H(1) antagonists in amygdala-kindled rats.

  Brain research 20031121

• Histamine H3 receptors regulate vascular permeability changes in the skin of mast cell-deficient mice.

  International immunopharmacology 20031101

• Possible role of L-carnosine in the regulation of blood glucose through controlling autonomic nerves.

  Experimental biology and medicine (Maywood, N.J.) 20031101

• Acute upper airway angioedema secondary to acquired C1 esterase inhibitor deficiency: a case report.

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 20031101

• Antihistamine-induced rhabdomyolysis.

  Southern medical journal 20031001

• A comparison of the effect of diphenhydramine and desloratadine on vigilance and cognitive function during treatment of ragweed-induced allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20031001

• Catanionic drug-surfactant mixtures: phase behavior and sustained release from gels.

  Pharmaceutical research 20031001

• Management of an anaphylactoid reaction to methotrexate with a stepwise graded challenge.

  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20031001

• Comment: Rhabdomyolysis and acute renal failure following an ethanol and diphenhydramine overdose.

  The Annals of pharmacotherapy 20030901

• Safety of first-generation antihistamines.

  The Journal of family practice 20030901

• Springtime confusion: are consumers getting the right information on how to treat seasonal allergies?

  The Journal of allergy and clinical immunology 20030901

• Comparative pharmacokinetics of diphenhydramine in camels and horses after intravenous administration.

  Veterinary research communications 20030901

• Driving ability after acute and sub-chronic administration of levocetirizine and diphenhydramine: a randomized, double-blind, placebo-controlled trial.

  Psychopharmacology 20030801

• A study of the effects of curing and storage conditions on controlled release diphenhydramine HCl pellets coated with Eudragit NE30D.

  Pharmaceutical development and technology 20030801

• Multicenter phase II trial of weekly paclitaxel for advanced or metastatic breast cancer: the Saitama Breast Cancer Clinical Study Group (SBCCSG-01).

  Japanese journal of clinical oncology 20030801

• Cells in midline thalamus, central amygdala, and nucleus accumbens responding specifically to antipsychotic drugs.

  Psychopharmacology 20030601

• Histamine up-regulates phosphodiesterase IV activity in U-937 cells through H2 receptor stimulation and cAMP increase.

  Medical science monitor : international medical journal of experimental and clinical research 20030601

• Acute pharmacological effects of temazepam, diphenhydramine, and valerian in healthy elderly subjects.

  Journal of clinical psychopharmacology 20030601

• Pharmacokinetics of diphenhydramine in healthy volunteers with a dimenhydrinate 25 mg chewing gum formulation.

  Methods and findings in experimental and clinical pharmacology 20030601

• Hypersensitivity and idiosyncratic reactions to oxaliplatin.

  Cancer 20030501

• Effects of fexofenadine, diphenhydramine, and placebo on performance of the test of variables of attention (TOVA).

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030501

• Diphenhydramine-induced wide complex dysrhythmia responds to treatment with sodium bicarbonate.

  The American journal of emergency medicine 20030501

• Neurosteroid-induced hyperalgesia through a histamine release is inhibited by progesterone and p,p'-DDE, an endocrine disrupting chemical.

  Neurochemistry international 20030401

• A new isoquinolinone derivative with noble vasorelaxation activity.

  Pharmacology 20030401

• Rhabdomyolysis and acute renal failure following an ethanol and diphenhydramine overdose.

  The Annals of pharmacotherapy 20030401

• An 89-year-old woman with angioedema during t-PA infusion for acute ischemic stroke.

  Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association 20030401

• Early death due to severe organophosphate poisoning is a centrally mediated process.

  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20030401

• Management of vaso-occlusive pain in children with sickle cell disease.

  Journal of pediatric hematology/oncology 20030401

• Carboplatin hypersensitivity reactions: re-treatment with cisplatin desensitisation.

  Gynecologic oncology 20030401

• Antihistamine meta-analysis leaves uncertainty.

  The Journal of allergy and clinical immunology 20030401

• Sedation and performance impairment of diphenhydramine and second-generation antihistamines: a meta-analysis.

  The Journal of allergy and clinical immunology 20030401

• The effects of histamine on the lipopolysaccharide-induced metallothionein-I mRNA expression in the mouse spleen.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030401

• Dimenhydrinate produces a conditioned place preference in rats.

  Pharmacology, biochemistry, and behavior 20030401

• Acute and subchronic effects of levocetirizine and diphenhydramine on memory functioning, psychomotor performance, and mood.

  The Journal of allergy and clinical immunology 20030301

• Fatal diphenhydramine intoxication in infants.

  Journal of forensic sciences 20030301

• Simultaneous determination of naphazoline, diphenhydramine and phenylephrine in nasal solutions by capillary electrophoresis.

  Journal of pharmaceutical and biomedical analysis 20030205

• An allergic reaction to intraarterial nonionic contrast material.

  AJNR. American journal of neuroradiology 20030201

• Rhabdomyolysis associated with unintentional antihistamine overdose in a child.

  Pediatric emergency care 20030201

• The effects of single-dose fexofenadine, diphenhydramine, and placebo on cognitive performance in flight personnel.

  Aviation, space, and environmental medicine 20030201

• Diphenhydramine and hyaluronic acid derivatives reduce adnexal adhesions and prevent tubal obstructions in rats.

  European journal of obstetrics, gynecology, and reproductive biology 20030110

• Variations among emergency departments in the treatment of benign headache.

  Annals of emergency medicine 20030101

• Rare systemic dermatologic reaction after pneumococcal vaccine administration.

  Southern medical journal 20030101

• Sedative-hypnotic use of diphenhydramine in a rural, older adult, community-based cohort: effects on cognition.

  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20030101

• Safe driving reminders.

  Diabetes self-management 20030101

• Envenomation by the Mexican beaded lizard: a case report.

  Journal of toxicology. Clinical toxicology 20030101

• [Tongue angioedema associated with angiotensin-converting enzyme inhibitor (diagnosis, differential diagnosis, treatment)].

  Medicina (Kaunas, Lithuania) 20030101

• Pleural fluid eosinophilia with combined pharmacotherapy.

  Psychosomatics 20030101

• Symptomatic treatment of the cough in whooping cough.

  The Cochrane database of systematic reviews 20030101

• Diphenhydramine-induced amnesia is mediated by Gi-protein activation.

  Neuroscience 20030101

• Comprehensive nursing approach to infliximab infusion therapy.

  Journal of infusion nursing : the official publication of the Infusion Nurses Society 20030101

• [Significance of chromatographic methods coupled with mass spectrometry for identification of drugs for medico-legal purposes exemplified by chlorphenoxamine].

  Archiwum medycyny sadowej i kryminologii 20030101

• [Case of corneal actinomycosis].

  Vestnik oftalmologii 20030101

• [Effect of adrenergic and histaminergic disorders on the subclinical course of atopic bronchial asthma].

  Klinicheskaia meditsina 20030101

• Pharmaceutical drug overdose case reports. From the World Literature.

  Toxicological reviews 20030101

• Polymyositis: rare complication of hepatitis B vaccination. An unusual cause of toxic shock syndrome.

  Boletin de la Asociacion Medica de Puerto Rico 20030101

• Labeling of diphenhydramine-containing drug products for over-the-counter human use. Final rule.

  Federal register 20021202

• Diphenhydramine as a protective agent in a rat model of acute, lethal organophosphate poisoning.

  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20021201

• Inhibition of Na(+) current by imipramine and related compounds: different binding kinetics as an inactivation stabilizer and as an open channel blocker.

  Molecular pharmacology 20021101

• Cocaine-induced anxiety: alleviation by diazepam, but not buspirone, dimenhydrinate or diphenhydramine.

  Behavioural pharmacology 20021101

• Effects of metergoline on symptoms in women with premenstrual dysphoric disorder.

  The American journal of psychiatry 20021101

• [Paclitaxel hypersensitivity reactions in patients with advanced ovarian carcinoma].

  Ginekologia polska 20021101

• Simultaneous determination of dextromethorphan, diphenhydramine and phenylephrine in expectorant and decongestant syrups by capillary electrophoresis.

  Journal of pharmaceutical and biomedical analysis 20021015

• Tolerance to daytime sedative effects of H1 antihistamines.

  Journal of clinical psychopharmacology 20021001

• The use of physostigmine in diphenhydramine overdose.

  The American journal of emergency medicine 20021001

• Possible role of mast cells in cineole-induced scratching behavior in mice.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021001

• Murine tumor necrosis factor-alpha sensitizes plasma corticosterone activity and the manifestation of shock: modulation by histamine.

  Journal of neuroimmunology 20021001

• Of injuries and antihistamines and dosing.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020901

• Increased risk of serious injury following an initial prescription for diphenhydramine.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020901

• Determination of diphenhydramine hydrochloride in some single tertiary alkylamine pharmaceutical preparations by flow injection spectrophotometry.

  Journal of pharmaceutical and biomedical analysis 20020822

• Transport mechanisms of nicotine across the human intestinal epithelial cell line Caco-2.

  The Journal of pharmacology and experimental therapeutics 20020801

• Isosulfan blue dye reactions during sentinel lymph node mapping for breast cancer.

  Anesthesia and analgesia 20020801

• Comparison of effects of lidocaine hydrochloride, buffered lidocaine, diphenhydramine, and normal saline after intradermal injection.

  Journal of clinical anesthesia 20020801

• Biocompatibility of thermosensitive chitosan-based hydrogels: an in vivo experimental approach to injectable biomaterials.

  Biomaterials 20020701

• Acetaminophen and diphenhydramine as premedication for platelet transfusions: a prospective randomized double-blind placebo-controlled trial.

  American journal of hematology 20020701

• The South African Community Epidemiology Network on Drug Use (SACENDU) project, phases 1-8--cannabis and Mandrax.

  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20020701

• Toxicological screening for drugs of abuse in samples adulterated with household chemicals.

  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20020701

• Using intravenous diphenhydramine to minimize back pain associated with photodynamic therapy with verteporfin.

  Archives of ophthalmology (Chicago, Ill. : 1960) 20020601

• Anti-allergic effects of cnidii monnieri fructus (dried fruits of Cnidium monnieri) and its major component, osthol.

  Biological & pharmaceutical bulletin 20020601

• Occupational allergy caused by Peruvian lily (Alstroemeria).

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020601

• Drug release from Kollicoat SR 30D-coated nonpareil beads: evaluation of coating level, plasticizer type, and curing condition.

  AAPS PharmSciTech 20020601

• Akathisia: problematic but preventable.

  Annals of emergency medicine 20020501

• [Diphenhydramine is useful in a parturient with hypersensitivity to local anesthetics to manage her delivery].

  Masui. The Japanese journal of anesthesiology 20020501

• Biological mechanisms underlying voice changes due to dehydration.

  Journal of speech, language, and hearing research : JSLHR 20020401

• Investigation of the effect of tablet surface area/volume on drug release from hydroxypropylmethylcellulose controlled-release matrix tablets.

  Drug development and industrial pharmacy 20020401

• Association of diphenhydramine use with adverse effects in hospitalized older patients: possible confounders.

  Archives of internal medicine 20020325

• Monoamine depletion in unmedicated depressed subjects.

  Biological psychiatry 20020315

• A comparison of two prophylactic regimens for hypersensitivity reactions to paclitaxel.

  Gynecologic oncology 20020301

• Potential anaphylactic shock with abciximab readministration.

  Pharmacotherapy 20020301

• Cationic amphiphilic drugs and platelet phospholipase A(2) (cPLA(2)).

  Thrombosis research 20020215

• Physostigmine, sodium bicarbonate, or hypertonic saline to treat diphenhydramine toxicity.

  Veterinary and human toxicology 20020201

• [Weekly administration of low-dose paclitaxel for advanced or metastatic breast cancer].

  Gan to kagaku ryoho. Cancer & chemotherapy 20020201

• Anti-CD44 monoclonal antibody (IM7) induces murine systemic shock mediated by platelet activating factor.

  Journal of autoimmunity 20020201

• Tracking the cognitive pharmacodynamics of psychoactive substances with combinations of behavioral and neurophysiological measures.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20020101

• [Efficacy of biweekly paclitaxel therapy in advanced or recurrent breast cancer].

  Gan to kagaku ryoho. Cancer & chemotherapy 20020101

• Visual hallucinations induced by the combination of prolintane and diphenhydramine.

  Pharmacopsychiatry 20020101

• Titrimetric and spectrophotometric assay of some antihistamines through the determination of the chloride of their hydrochlorides.

  Farmaco (Societa chimica italiana : 1989) 20020101

• Antihistamine antinociception is mediated by Gi-protein activation.

  Neuroscience 20020101

• Antihistamines in the management of canine atopic dermatitis: a retrospective study of 171 dogs (1992-1998).

  Veterinary therapeutics : research in applied veterinary medicine 20020101

• Phase II study of docetaxel in patients with pancreatic cancer previously untreated with cytotoxic chemotherapy.

  Cancer investigation 20020101

• Food-dependent exercise-induced anaphylaxis.

  Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors 20020101

• Managing patients with local anesthetic complications using alternative methods.

  Pennsylvania dental journal 20020101

• Premedication strategy for weekly paclitaxel.

  Cancer investigation 20020101

• Development and implementation of a carboplatin desensitization protocol for children with neurofibromatosis, type 1 and hypersensitivity reactions in an outpatient oncology clinic.

  Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses 20020101

• Envenomation by the Vietnamese centipede in a Long Island pet store.

  Journal of toxicology. Clinical toxicology 20020101

• Effects of terfenadine and diphenhydramine on the CYP2D6 activity in healthy volunteers.

  European journal of drug metabolism and pharmacokinetics 20020101

• The effects of diphenhydramine and SR142948A on periaqueductal gray neurons and on the interactions between the medial preoptic nucleus and the periaqueductal gray.

  Neuroscience 20020101

• [Drug therapy in the old age. Drug effects in the elderly].

  MMW Fortschritte der Medizin 20011213

• Postmortem diffusion of drugs from the bladder into femoral venous blood.

  Forensic science international 20011201

• Relative sensitivity to alfentanil and reliability of current perception threshold vs von Frey tactile stimulation and thermal sensory testing.

  Journal of the peripheral nervous system : JPNS 20011201

• Standard treatment: the role of antihistamines.

  The journal of investigative dermatology. Symposium proceedings 20011101

• A contemporaneous finding of fenproporex in a polydrug suicide.

  Journal of analytical toxicology 20011001

• Adenosine-mediated hypotension in in vivo guinea-pig: receptors involved and role of NO.

  British journal of pharmacology 20011001

• Cognitive and other adverse effects of diphenhydramine use in hospitalized older patients.

  Archives of internal medicine 20010924

• Modulation of smooth muscle proliferation in rat carotid artery by platelet-derived mediators and fibroblast growth factor-2.

  Platelets 20010901

• Do antihistamines impair school performance in children?

  The Journal of family practice 20010901

• Metabotropic neurosteroid/sigma-receptor involved in stimulation of nociceptor endings of mice.

  The Journal of pharmacology and experimental therapeutics 20010801

• Diphenhydramine as an analgesic adjuvant in refractory cancer pain.

  Journal of pain and symptom management 20010801

• Histaminergic regulation of smooth muscles in rabbit pulmonary arteries.

  Bulletin of experimental biology and medicine 20010801

• Effects of vasopressin on histamine H(1) receptor antagonist-induced spatial memory deficits in rats.

  European journal of pharmacology 20010706

• Suppressive effects of histamine H1 receptor antagonist diphenhydramine on the leukocyte infiltration during endotoxin-induced uveitis.

  Experimental eye research 20010701

• Effect of H1-antagonists on spatial memory deficit evaluated by 8-arm radial maze in rats.

  Acta pharmacologica Sinica 20010701

• Effect of fructose-1, 6-diphosphate versus diphenhydramine on mortality in compound 48/80-induced shock.

  Toxicology letters 20010620

• Localized heat urticaria: a clinical study using laser Doppler flowmetry.

  Journal of dermatological science 20010601

• Pegylated liposomal doxorubicin: tolerability and toxicity.

  Pharmacotherapy 20010601

• Effects of diphenhydramine HCl and methylprednisolone in the prevention of abdominal adhesions.

  American journal of surgery 20010601

• Study of crystallization of endogenous surfactant in Eudragit NE30D-free films and its influence on drug-release properties of controlled-release diphenhydramine HCl pellets coated with Eudragit NE30D.

  AAPS pharmSci 20010601

• An urticarial IgE-mediated reaction to interferon beta-1b.

  Neurology 20010522

• Simultaneous determination of flupirtine and its major active metabolite in human plasma by liquid chromatography-tandem mass spectrometry.

  Journal of chromatography. B, Biomedical sciences and applications 20010505

• Histamine-induced production of interleukin-6 and interleukin-8 by human coronary artery endothelial cells is enhanced by endotoxin and tumor necrosis factor-alpha.

  Microvascular research 20010501

• Children's school performance is not impaired by short-term administration of diphenhydramine or loratadine.

  The Journal of pediatrics 20010501

• Newer antihistamines.

  The Medical letter on drugs and therapeutics 20010430

• Diphenhydramine alters the disposition of venlafaxine through inhibition of CYP2D6 activity in humans.

  Journal of clinical psychopharmacology 20010401

• Indirect atomic absorption determination of atropine, diphenhydramine, tolazoline, and levamisole based on formation of ion-associates with potassium tetraiodometrcurate.

  Journal of pharmaceutical and biomedical analysis 20010401

• Cost savings with intramuscular anticholinergics.

  The Journal of clinical psychiatry 20010401

• Vitrification of mouse oocytes using a nylon loop.

  Molecular reproduction and development 20010301

• Effects of histamine-1 receptor antagonism on leukocyte-independent plasma extravasation during endotoxemia.

  Journal of critical care 20010301

• Skin concentrations of H1-receptor antagonists.

  The Journal of allergy and clinical immunology 20010301

• Control of impurities in diphenhydramine hydrochloride by an ion-pairing, reverse liquid chromatography method.

  The Journal of pharmacy and pharmacology 20010301

• Diphenhydramine dependence.

  Addiction (Abingdon, England) 20010301

• Characterization of a novel cationic drug transporter in human retinal pigment epithelial cells.

  The Journal of pharmacology and experimental therapeutics 20010201

• Diphenhydramine for the prevention of akathisia induced by prochlorperazine: a randomized, controlled trial.

  Annals of emergency medicine 20010201

• Let the user beware. OTC drugs aren't necessarily 'safe when taken as directed.'.

  The American journal of nursing 20010201

• Radial entrapment neuropathy due to chronic injection-induced triceps fibrosis.

  Muscle & nerve 20010101

• pH-independent large-volume sample stacking of positive or negative analytes in capillary electrophoresis.

  Electrophoresis 20010101

• Delayed life-threatening reaction to anthrax vaccine.

  Journal of toxicology. Clinical toxicology 20010101

• Effects of formulation variables and post-compression curing on drug release from a new sustained-release matrix material: polyvinylacetate-povidone.

  Pharmaceutical development and technology 20010101

• Burn wound itch control using H1 and H2 antagonists.

  The Journal of burn care & rehabilitation 20010101

• Microporous material from kanemite for drug inclusion and release.

  Farmaco (Societa chimica italiana : 1989) 20010101

• [Effects of individual premedication on ocular hemo- and hydrodynamics in patients with cataracts].

  Vestnik oftalmologii 20010101

• Dissociable effects of histamine H1 antagonists on reaction-time performance in rats.

  Pharmacology, biochemistry, and behavior 20010101

• Pharmacological intervention with platelet phospholipase A2.

  Bratislavske lekarske listy 20010101

• Emergency! Prochlorperazine-induced dystonia.

  The American journal of nursing 19991101

• Central nervous system effects of H1-receptor antagonists in the elderly.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 19990201

• Examination of low-incidence brain tumor responses in F344 rats following chemical exposures in National Toxicology Program carcinogenicity studies.

  Toxicologic pathology 19990101

• Randomized trial of diphenhydramine versus benzyl alcohol with epinephrine as an alternative to lidocaine local anesthesia.

  Annals of emergency medicine 19981201

• Management of anaphylactoid reactions to intravenous N-acetylcysteine.

  Annals of emergency medicine 19980601

• Effect of pertussis toxin on baclofen- and diphenhydramine-induced amnesia.

  Psychopharmacology 19980401

• Identification of medications that cause cognitive impairment in older people: the case of oxybutynin chloride.

  Journal of the American Geriatrics Society 19980101

• Identification of drug-related cognitive impairment in older individuals. Challenge studies with diphenhydramine.

  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 19970101

• Evaluation of inhibitory effect of diphenhydramine on benzodiazepine dependence in rats.

  Indian journal of physiology and pharmacology 19970101

• Phase I dose-escalation trial of paclitaxel and ifosfamide in patients with advanced non-small cell lung cancer.

  Seminars in oncology 19961201

• [An anticholinergic syndrome with hallucinatory psychosis after diphenhydramine poisoning].

  Deutsche medizinische Wochenschrift (1946) 19951208

• Dystonic reaction following recommended use of a cold syrup.

  Annals of emergency medicine 19951201

• Neuropharmacological mechanisms of emesis. I. Effects of antiemetic drugs on motion- and apomorphine-induced pica in rats.

  Methods and findings in experimental and clinical pharmacology 19951101

• Treatment of HIV-associated Kaposi's sarcoma with paclitaxel.

  Lancet (London, England) 19950701

• Cutaneous mast cell degranulation in rats receiving injections of recombinant human interleukin-1 receptor antagonist (rhIL-1ra) and/or its vehicle: possible clinical implications.

  The Journal of laboratory and clinical medicine 19950401

• Pretreatment regimens for adverse events related to infusion of amphotericin B.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 19950401

• Phenytoin-induced movement disorder. Unilateral presentation in a child and response to diphenhydramine.

  Clinical pediatrics 19941001

• Diphenhydramine-induced acute dystonia.

  Pharmacotherapy 19940101

• Evaluation of the rat embryo culture system as a predictive test for human teratogens.

  Canadian journal of physiology and pharmacology 19940101

• Seizures associated with poisoning and drug overdose.

  The American journal of emergency medicine 19931101

• Double-blinded comparison of diphenhydramine versus lidocaine as a local anesthetic.

  Annals of emergency medicine 19930901

• The effect of antihistamines on the immediate allergic response: a comparative review.

  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 19930601

• Drug-induced dystonia in a patient with C4 quadriplegia. Case report.

  American journal of physical medicine & rehabilitation 19930401

• Drug-induced, life-threatening angioedema revisited.

  The Laryngoscope 19930101

• Comparison of kinin-forming and amidolytic activities of four trimucases, oedema-producing and kinin-releasing enzymes, from Trimeresurus mucrosquamatus venom.

  The Journal of pharmacy and pharmacology 19920401

• Controlled trial of H1 antagonists in the treatment of chronic idiopathic urticaria.

  Annals of allergy 19911001

• Spastic torticollis during general anesthesia: case report and review of receptor mechanisms.

  Anesthesiology 19910801

• Diphenhydramine prevents the haemodynamic changes of cimetidine in ICU patients.

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 19910301

• Diphenhydramine toxicity in three children with varicella-zoster infection.

  DICP : the annals of pharmacotherapy 19910201

• Histamine blockade and cardiovascular changes following heparin administration during cardiac surgery.

  Journal of cardiothoracic anesthesia 19901201

• Acute psychosis after amantadine overdose.

  Annals of emergency medicine 19900601

• Enalapril induced angioedema.

  The American journal of emergency medicine 19900301

• Contribution of prostacyclin to D-tubocurarine-induced hypotension in humans.

  Anesthesiology 19900101

• Comparison of cimetidine and diphenhydramine in the treatment of acute urticaria.

  Annals of emergency medicine 19900101

• Diphenhydramine and acute dystonia.

  Annals of internal medicine 19890701

• Dystonia presenting as upper airway obstruction.

  The Journal of emergency medicine 19890101

• Combined H1 and H2 receptor blockade attenuates the cardiovascular effects of high-dose atracurium for rapid sequence endotracheal intubation.

  Anesthesia and analgesia 19881101

• Diphenhydramine reversal of vancomycin-induced hypotension.

  Anesthesia and analgesia 19881101

• Clinical use of the total dose intravenous infusion of iron dextran.

  The Journal of laboratory and clinical medicine 19880501

• Acute dystonic reaction due to diazepam.

  The Journal of emergency medicine 19880101

• Acute dystonia from etoposide.

  Drug intelligence & clinical pharmacy 19880101

• [Influence of kordaron, anaprilin, dimedrol and riboxin on the hemodynamic effects of strophanthin in experimental heart failure].

  Farmakologiia i toksikologiia 19880101

• Tagamet-induced acute dystonia.

  Annals of emergency medicine 19871001

• Unusual treatment response of a severe dystonia to diphenhydramine.

  Annals of emergency medicine 19870601

• Pharmacologic analysis of LY188695 (KB-2413), 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)-benzimidazole difumarate, a potent histamine1 receptor antagonist.

  Agents and actions 19870201

• Antihistaminics enhance morphine-, but not amphetamine- and scopolamine-induced hyperactivity in mice.

  Psychopharmacology 19870101

• Life-threatening hypotensive reactions to contrast media administration: comparison of pharmacologic and fluid therapy.

  Radiology 19870101

• Enhancement of morphine-induced hyperactivity by antihistaminic drugs in mice.

  Archives internationales de pharmacodynamie et de therapie 19861201

• Toxic encephalopathy caused by topically applied diphenhydramine.

  The Journal of pediatrics 19860601

• Metoclopramide: dose-related toxicity and preliminary antiemetic studies in children receiving cancer chemotherapy.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19850801

• The effects of H1 and H2 histamine receptor antagonists on the development of endotoxemia in the conscious, unrestrained rat.

  Circulatory shock 19850101

• Clinical pharmacokinetics of H1-receptor antagonists (the antihistamines).

  Clinical pharmacokinetics 19850101

• Acute dystonic reactions to neuroleptic drugs.

  Anesthesia progress 19840101

• Treatment of valproate tremors.

  Neurology 19831001

• The effect of antihistaminics on cataleptogenic action of analgesics and haloperidol.

  Polish journal of pharmacology and pharmacy 19830101

• Phenothiazine induced lingual trauma.

  The Laryngoscope 19830101

• Peripheral hypotensive and central hypertensive effects of cimetidine.

  Agents and actions 19820401

• Decorticate posture following 'cardiac cocktail': a transient complication of sedation for catheterization.

  Pediatric cardiology 19820101

• Extrapyramidal reaction to fluphenazine potentiated by thyrotoxicosis.

  The American journal of psychiatry 19810201

• [Acute-onset extrapyramidal syndromes caused by drugs].

  Boletin medico del Hospital Infantil de Mexico 19810101

• [Resuscitation in acute allergic reactions to drugs].

  Vestnik khirurgii imeni I. I. Grekova 19801101

• Explained unexplained anisocoria.

  JAMA 19800926

• The stimulatory effects of neurotensin and related peptides in rat stomach strips and guinea-pig atria.

  British journal of pharmacology 19800101

• Immune complex disease associated with Peroben intake.

  Dermatologica 19790101

• Dyskinesias after antihistamine use.

  The New England journal of medicine 19770113

• Acute dystonia. An unusal reaction to diphenhydramine.

  JAMA 19760719

• The use of flurazepam (dalmane) as a substitute for barbiturates and methaqualone/diphenhydramine (mandrax) in general practice.

  The Journal of international medical research 19760101

• Physostigmine reversal of antihistamine-induced excitement and depression.

  Anesthesiology 19751201

• Letter: Neurotoxic reaction to haloperidol in a thyrotoxic patient.

  The New England journal of medicine 19750724

• Cholinesterase inhibition by phenothiazine and nonphenothiazine antihistaminics: analysis of its postulated role in synergizing organophosphate toxicity.

  Toxicology and applied pharmacology 19750201

• Dyskinesia-an unusual reaction to ethosuximide.

  Archives of neurology 19750201

• Letter: Dyskinesia after fenfluramine.

  The New England journal of medicine 19740822

• Postburn convulsive disorders in children.

  The Journal of trauma 19740501

• Chlorpromazine causing extrapyramidal dysfunction in newborn infant of psychotic mother.

  New York state journal of medicine 19740401

• The mechanism of the potentiating effect of antidepressant drugs on the protective influenc oe of diphenhydramine in experimental catatonia. The role of histamine.

  Pharmacology 19740101

• Hepatitis with encephalitis: dystonic reactions from various drugs.

  Proceedings of the Royal Society of Medicine 19730301

• A rare allergic reaction to sodium methohexital.

  Journal of oral surgery (American Dental Association : 1965) 19721201

• Effects of diphenhydramine and dimenhydrinate on vestibular neuronal activity of cat: a search for the locus of their antimotion sickness action.

  The Journal of pharmacology and experimental therapeutics 19710301

• The effects of diazepam or diphenhydramine on healthy human subjects.

  Psychopharmacologia 19710101

• Unexpected danger of diazepam.

  British medical journal 19700425

• Reaction to prochlorperazine?

  Lancet (London, England) 19690412

• Antiarrhythmic activity of some isoquinoline derivatives determined by a rapid screening procedure in the mouse.

  The Journal of pharmacology and experimental therapeutics 19680301

• Toxic psychosis due to diphenhydramine hydrochloride.

  JAMA 19680122

• An unusual vasculitis due to diphenhydramine. Cutaneous and central nervous system involvement.

  Archives of dermatology 19651101

• [ANTIEMETIC ACTION OF METOCLOPRAMIDE WITH RESPECT TO APOMORPHINE AND HYDERGINE].

  Comptes rendus des seances de la Societe de biologie et de ses filiales 19640101