147127-19-3 | (S)-(((1-(6-Amino-9h-purin-9-yl)propan-2-yl)oxy)methyl)phosphonic acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$41.00	$29.00
1g	95%	in stock	$50.00	$35.00
5g	95%	in stock	$194.00	$136.00
10g	95%	in stock	$353.00	$247.00
25g	95%	in stock	$881.00	$617.00

Description

• Catalog Number: AA65411
• Chemical Name: (S)-(((1-(6-Amino-9h-purin-9-yl)propan-2-yl)oxy)methyl)phosphonic acid
• CAS Number: 147127-19-3
• Molecular Formula: C9H14N5O4P
• Molecular Weight: 287.2123
• MDL Number: MFCD21604708
• SMILES: C[C@@H](Cn1cnc2c1ncnc2N)OCP(=O)(O)O

Computed Properties

• Complexity: 354
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 19
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 5
• XLogP3: -1.6

Literature

• A phenyl-thiadiazolylidene-amine derivative ejects zinc from retroviral nucleocapsid zinc fingers and inactivates HIV virions.

  Retrovirology 20120101

• Activity of the (R)-enantiomers of 9-(2-phosphonylmethoxypropyl)-adenine and 9-(2-phosphonylmethoxypropyl)-2,6-diaminopurine against human immunodeficiency virus in different human cell systems.

  Biochemical and biophysical research communications 19960215

• Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine.

  Antimicrobial agents and chemotherapy 19930201