148-18-5 | N,N-diethyl(sodiosulfanyl)carbothioamide

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$34.00	$24.00
5g	98%	in stock	$74.00	$52.00
25g	95%	in stock	$103.00	$72.00
100g	95%	in stock	$178.00	$124.00

Description

• Catalog Number: AA66363
• Chemical Name: N,N-diethyl(sodiosulfanyl)carbothioamide
• CAS Number: 148-18-5
• Molecular Formula: C5H10NNaS2
• Molecular Weight: 171.2594
• MDL Number: MFCD00150617
• SMILES: CCN(C(=S)[S-])CC.[Na+]

Computed Properties

• Complexity: 83
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2

Literature

• A positive feedback loop between nitric oxide and amyloid β (1-42) accelerates mitochondrial damage in human lens epithelial cells.

  Toxicology 20170415

• Zinc diethyldithiocarbamate as an inducer of metallothionein in cultured vascular endothelial cells.

  The Journal of toxicological sciences 20160401

• Induction of metallothionein isoforms by copper diethyldithiocarbamate in cultured vascular endothelial cells.

  The Journal of toxicological sciences 20160401

• Three kinds of Ganoderma lucidum polysaccharides attenuate DDC-induced chronic pancreatitis in mice.

  Chemico-biological interactions 20160305

• Cytoprotective effect of eckol against oxidative stress-induced mitochondrial dysfunction: involvement of the FoxO3a/AMPK pathway.

  Journal of cellular biochemistry 20140801

• RTP801 regulates maneb- and mancozeb-induced cytotoxicity via NF-κB.

  Journal of biochemical and molecular toxicology 20140701

• Diethyldithiocarbamate induces apoptosis in neuroblastoma cells by raising the intracellular copper level, triggering cytochrome c release and caspase activation.

  Toxicology in vitro : an international journal published in association with BIBRA 20130201

• The effects of sodium diethyldithiocarbamate in fibroblasts V79 cells in relation to cytotoxicity, antioxidative enzymes, glutathione, and apoptosis.

  Archives of toxicology 20121201

• Anion inhibition studies of the fastest carbonic anhydrase (CA) known, the extremo-CA from the bacterium Sulfurihydrogenibium azorense.

  Bioorganic & medicinal chemistry letters 20121201

• Electrophilic adduction of ubiquitin activating enzyme E1 by N,N-diethyldithiocarbamate inhibits ubiquitin activation and is accompanied by striatal injury in the rat.

  Chemical research in toxicology 20121119

• New insight into hyperthermic intraperitoneal chemotherapy: induction of oxidative stress dramatically enhanced tumor killing in in vitro and in vivo models.

  Annals of surgery 20121101

• Defensive effect of natrium diethyldithiocarbamate trihydrate (NDDCT) and lisinopril in DOCA-salt hypertension-induced vascular dementia in rats.

  Psychopharmacology 20121001

• Diethyldithiocarbamate complex with copper: the mechanism of action in cancer cells.

  Mini reviews in medicinal chemistry 20121001

• Hydrogen sulfide mediates hypoxic vasoconstriction through a production of mitochondrial ROS in trout gills.

  American journal of physiology. Regulatory, integrative and comparative physiology 20120901

• Anion inhibition studies of an α-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1.

  Bioorganic & medicinal chemistry letters 20120901

• Salutary effect of NFκB inhibitor and folacin in hyperhomocysteinemia-hyperlipidemia induced vascular dementia.

  Progress in neuro-psychopharmacology & biological psychiatry 20120807

• Synergistic enhancement effect of room temperature ionic liquids for cloud point extraction combined with UV-vis spectrophotometric determination nickel in environmental samples.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120801

• Enhancement of μ-opioid receptor desensitization by nitric oxide in rat locus coeruleus neurons: involvement of reactive oxygen species.

  The Journal of pharmacology and experimental therapeutics 20120801

• Antitubercular activity of disulfiram, an antialcoholism drug, against multidrug- and extensively drug-resistant Mycobacterium tuberculosis isolates.

  Antimicrobial agents and chemotherapy 20120801

• The use of thallium diethyldithiocarbamate for mapping CNS potassium metabolism and neuronal activity: Tl+ -redistribution, Tl+ -kinetics and Tl+ -equilibrium distribution.

  Journal of neurochemistry 20120701

• Effects of the fungicide metiram in outdoor freshwater microcosms: responses of invertebrates, primary producers and microbes.

  Ecotoxicology (London, England) 20120701

• Solidified floating organic drop microextraction combined with ETV-ICP-MS for the determination of trace heavy metals in environmental water samples.

  Talanta 20120530

• A comparative study of stress-mediated immunological functions with the adjuvanticity of alum.

  The Journal of biological chemistry 20120518

• Diethyldithiocarbamate induces apoptosis in HHV-8-infected primary effusion lymphoma cells via inhibition of the NF-κB pathway.

  International journal of oncology 20120401

• Carbon tetrachloride-mediated lipid peroxidation induces early mitochondrial alterations in mouse liver.

  Laboratory investigation; a journal of technical methods and pathology 20120301

• Dithiocarbamates strongly inhibit carbonic anhydrases and show antiglaucoma action in vivo.

  Journal of medicinal chemistry 20120223

• Uptake of dissolved organic carbon-complexed ⁶⁵Cu by the green mussel Perna viridis.

  Environmental science & technology 20120221

• Positive patch test reactions in older individuals: retrospective analysis from the North American Contact Dermatitis Group, 1994-2008.

  Journal of the American Academy of Dermatology 20120201

• Anion inhibition studies of an α-carbonic anhydrase from the living fossil Astrosclera willeyana.

  Bioorganic & medicinal chemistry letters 20120201

• The use of outer filter effects for Cu(2+) quantitation: a unique example for monitoring nonfluorescent molecule with fluorescence.

  Luminescence : the journal of biological and chemical luminescence 20120101

• A novel micellar electrokinetic chromatographic method for separation of metal-DDTC complexes.

  TheScientificWorldJournal 20120101

• Recovery of axonal myelination sheath and axonal caliber in the mouse corpus callosum following damage induced by N,N-diethyldithiocarbamate.

  The European journal of neuroscience 20111201

• Effect of chelating agents and stress factors on zinc content in paneth cells and prostate gland cells.

  Bulletin of experimental biology and medicine 20111201

• Inhibition of superoxide dismutase selectively suppresses growth of rat spinal motor neurons: comparison with phosphorylated neurofilament-containing spinal neurons.

  Brain research 20111124

• A simple, rapid and sensitive ultraviolet-visible spectrophotometric technique for the determination of ultra-trace copper based on injection-ultrasound-assisted dispersive liquid-liquid microextraction.

  The Analyst 20111107

• Influence of copper ions on the viability and cytotoxicity of Pseudomonas aeruginosa under conditions relevant to drinking water environments.

  International journal of hygiene and environmental health 20111101

• A jacalin-related lectin-like gene in wheat is a component of the plant defence system.

  Journal of experimental botany 20111101

• Removal of mercury (II) by dithiocarbamate surface functionalized magnetite particles: application to synthetic and natural spiked waters.

  Water research 20111101

• Diethyldithiocarbamate functionalized CdSe/CdS quantum dots as a fluorescent probe for copper ion detection.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111015

• The protective effects of ascorbic acid, cimetidine, and nifedipine on diethyldithiocarbamate-induced hepatic toxicity in albino rats.

  Drug and chemical toxicology 20111001

• Survival role of superoxide dismutase 1 on human granulosa luteinized cells in vitro.

  Endocrine regulations 20111001

• Cloud point extraction for determination of lead in blood samples of children, using different ligands prior to analysis by flame atomic absorption spectrometry: a multivariate study.

  Journal of hazardous materials 20110915

• Validated method using liquid chromatography-electrospray ionization tandem mass spectrometry for the determination of contamination of the exterior surface of vials containing platinum anticancer drugs.

  Talanta 20110915

• Effects of CYP inhibitors on precocene I metabolism and toxicity in rat liver slices.

  Chemico-biological interactions 20110905

• Hydrogen peroxide is produced by E. coli challenged haemocytes and regulates phagocytosis, in the medfly Ceratitis capitata. The active role of superoxide dismutase.

  Developmental and comparative immunology 20110801

• Inhibition studies with anions and small molecules of two novel β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium.

  Bioorganic & medicinal chemistry letters 20110615

• Bis[(dihydrogen pyrophosphato-κ(2)O,O')(2,2':6',2''-terpyridine-κ(3)N,N',N'')copper(II)] 4.5-hydrate.

  Acta crystallographica. Section C, Crystal structure communications 20110501

• Tempol administration, a superoxide dismutase mimetic, reduces hepatic vascular resistance and portal pressure in cirrhotic rats.

  Journal of hepatology 20110401

• The disulfiram metabolites S-methyl-N,N-diethyldithiocarbamoyl sulfoxide and S-methyl-N,N-diethylthiocarbamoyl sulfone irreversibly inactivate betaine aldehyde dehydrogenase from Pseudomonas aeruginosa, both in vitro and in situ, and arrest bacterial growth.

  Biochimie 20110201

• Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.

  Bioorganic & medicinal chemistry letters 20110201

• Purification and partial characterization of oxalate oxidase from leaves of forage Sorghum (Sorghum vulgare var. KH-105) seedlings.

  Indian journal of biochemistry & biophysics 20110201

• In vitro metabolism, glutathione conjugation, and CYP isoform specificity of epoxidation of 4-vinylphenol.

  Xenobiotica; the fate of foreign compounds in biological systems 20110101

• Inhibition of the β-carbonic anhydrase from Streptococcus pneumoniae by inorganic anions and small molecules: Toward innovative drug design of antiinfectives?

  Bioorganic & medicinal chemistry 20110101

• Ameliorative potential of sodium cromoglycate and diethyldithiocarbamic acid in restraint stress-induced behavioral alterations in rats.

  Pharmacological reports : PR 20110101

• Inhibition of nuclear factor kappa-B signaling reduces growth in medulloblastoma in vivo.

  BMC cancer 20110101

• Contact sensitization in Chinese patients with hand eczema.

  Dermatitis : contact, atopic, occupational, drug 20110101

• Sulfallate.

  Report on carcinogens : carcinogen profiles 20110101

• Chestnut species and jasmonic acid treatment influence development and community interactions of galls produced by the Asian chestnut gall wasp, Dryocosmus kuriphilus.

  Journal of insect science (Online) 20110101

• Mechanism-based inactivation of human CYP2E1 by diethyldithocarbamate.

  Drug metabolism and disposition: the biological fate of chemicals 20101201

• [Determination of 4 dithiocarbamate residues in 22 matrices by gas chromatography].

  Se pu = Chinese journal of chromatography 20101201

• Determination of sulfonamides in bovine milk with column-switching high performance liquid chromatography using surface imprinted silica with hydrophilic external layer as restricted access and selective extraction material.

  Journal of chromatography. A 20101112

• Preparation of the core-shell structure adriamycin lipiodol microemulsions and their synergistic anti-tumor effects with diethyldithiocarbamate in vivo.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20101101

• Displacement-dispersive liquid-liquid microextraction coupled with graphite furnace atomic absorption spectrometry for the selective determination of trace silver in environmental and geological samples.

  Talanta 20100815

• Coenzyme A-dependent aerobic metabolism of benzoate via epoxide formation.

  The Journal of biological chemistry 20100702

• Sequential extraction method for speciation of arsenate and arsenite in mineral soils.

  Analytical chemistry 20100701

• Determination of platinum traces contamination by graphite furnace atomic absorption spectrometry after preconcentration by cloud point extraction.

  Journal of hazardous materials 20100415

• Tau hyperphosphorylation and axonal damage induced by N,N-diethyldithiocarbamate (DEDTC) treatment along late postnatal development is followed by a rescue during adulthood.

  Journal of neuroscience research 20100401

• The effects of N-acetyl cysteine on the MG132 proteasome inhibitor-treated lung cancer cells in relation to cell growth, reactive oxygen species and glutathione.

  International journal of molecular medicine 20100401

• Effect of ZnCl2 and chelation of zinc ions by N,N-diethyldithiocarbamate (DEDTC) on the ERG b-wave amplitude from the isolated superfused vertebrate retina.

  Current eye research 20100401

• The changes of reactive oxygen species and glutathione by MG132, a proteasome inhibitor affect As4.1 juxtaglomerular cell growth and death.

  Chemico-biological interactions 20100330

• Rapid, colorimetric quantification of lipid from algal cultures.

  Journal of microbiological methods 20100301

• Carbonic anhydrase inhibitors. Inhibition of transmembrane isoforms IX, XII, and XIV with less investigated anions including trithiocarbonate and dithiocarbamate.

  Bioorganic & medicinal chemistry letters 20100301

• Zinc-dependent effects of small molecules on the insulin-sensitive transcription factor FOXO1a and gluconeogenic genes.

  Metallomics : integrated biometal science 20100301

• Attenuation of renal excretory responses to ANG II during inhibition of superoxide dismutase in anesthetized rats.

  American journal of physiology. Renal physiology 20100201

• Central administration of p-hydroxyamphetamine produces a behavioral stimulant effect in rodents: evidence for the involvement of dopaminergic systems.

  Psychopharmacology 20100201

• High-resolution mapping of neuronal activity using the lipophilic thallium chelate complex TlDDC: protocol and validation of the method.

  NeuroImage 20100101

• Inhibition of tumor proteasome activity by gold-dithiocarbamato complexes via both redox-dependent and -independent processes.

  Journal of cellular biochemistry 20100101

• Speciation and analysis of arsenic(III) and arsenic(V) by electrochemical hydride generation spectrophotometric method.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20100101

• Bioavailability and catalytic properties of copper and iron for Fenton chemistry in human cerebrospinal fluid.

  Redox report : communications in free radical research 20100101

• Chemical blocking of zinc ions in CNS increases neuronal damage following traumatic brain injury (TBI) in mice.

  PloS one 20100101

• Peripheral nerve and brain differ in their capacity to resolve N,N-diethyldithiocarbamate-mediated elevations in copper and oxidative injury.

  Toxicology 20100101

• Soccer shin guard reactions: allergic and irritant reactions.

  Dermatitis : contact, atopic, occupational, drug 20100101

• Lymphomatoid allergic contact dermatitis mimicking cutaneous T cell lymphoma.

  Dermatitis : contact, atopic, occupational, drug 20100101

• DETC induces Leishmania parasite killing in human in vitro and murine in vivo models: a promising therapeutic alternative in Leishmaniasis.

  PloS one 20100101

• Development of a methodology for the simultaneous determination of inorganic and organolead compounds using supercritical fluid extraction followed by gas chromatography-mass spectrometry and its application to environmental matrices.

  Talanta 20091215

• Ultrasound-assisted emulsification-microextraction combined with flame atomic absorption spectrometry for determination of trace cadmium in water samples.

  Talanta 20091215

• Synergetic enhancement effect of ionic liquid and diethyldithiocarbamate on the chemical vapor generation of nickel for its atomic fluorescence spectrometric determination in biological samples.

  Analytica chimica acta 20091012

• Heme oxygenase-1 induction modulates hypoxic pulmonary vasoconstriction through upregulation of ecSOD.

  American journal of physiology. Heart and circulatory physiology 20091001

• N,N-diethyldithiocarbamate promotes oxidative stress prior to myelin structural changes and increases myelin copper content.

  Toxicology and applied pharmacology 20090815

• Effect of Korean red ginseng on superoxide dismutase inhibitor-induced pancreatitis in rats: a histopathologic and immunohistochemical study.

  Pancreas 20090801

• The effects of N-acetyl cysteine, buthionine sulfoximine, diethyldithiocarbamate or 3-amino-1,2,4-triazole on antimycin A-treated Calu-6 lung cells in relation to cell growth, reactive oxygen species and glutathione.

  Oncology reports 20090801

• The effects of buthionine sulfoximine, diethyldithiocarbamate or 3-amino-1,2,4-triazole on propyl gallate-treated HeLa cells in relation to cell growth, reactive oxygen species and glutathione.

  International journal of molecular medicine 20090801

• Spray pyrolysis synthesis of ZnS nanoparticles from a single-source precursor.

  Nanotechnology 20090610

• Detection of phenoloxidase activity in early stages of the Pacific oyster Crassostrea gigas (Thunberg).

  Developmental and comparative immunology 20090501

• Failure of ditiocarb (diethyldithiocarbamate) therapy: was diet the reason?

  Current HIV research 20090501

• Uptake of hydrophobic metal complexes by three freshwater algae: unexpected influence of pH.

  Environmental science & technology 20090501

• Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I, II, III, VII and XIII with less investigated inorganic anions.

  Bioorganic & medicinal chemistry letters 20090401

• Dispersive liquid-liquid microextraction preconcentration of palladium in water samples and determination by graphite furnace atomic absorption spectrometry.

  Talanta 20090315

• Persistent pain is dependent on spinal mitochondrial antioxidant levels.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20090107

• Effect of metal chelating agents on pentylenetetrazole-induced seizure threshold in cholestatic mice.

  Seizure 20090101

• Nitrogen substituent polarity influences dithiocarbamate-mediated lipid oxidation, nerve copper accumulation, and myelin injury.

  Chemical research in toxicology 20090101

• Diethyl dithiocarbamic acid, a possible nuclear factor kappa B inhibitor, attenuates ischemic postconditioning-induced attenuation of cerebral ischemia-reperfusion injury in mice.

  Canadian journal of physiology and pharmacology 20090101

• Diethyldithiocarbamate potentiates the effects of protamine sulphate in the isolated rat uterus.

  Redox report : communications in free radical research 20090101

• Study of the nitric oxide level in the tissues of rat organs and its changes after a long-term inhalation of the air with increased NO content.

  Doklady. Biochemistry and biophysics 20090101

• Effect of diethyldithiocarbamate (DDC) and ticlopidine on CYP1A2 activity and caffeine metabolism: an in vitro comparative study with human cDNA-expressed CYP1A2 and liver microsomes.

  Pharmacological reports : PR 20090101

• Analytical variables affecting exchangeable copper determination in blood plasma.

  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20081201

• Ni(II), Cu(II), and Zn(II) diethyldithiocarbamate complexes show various activities against the proteasome in breast cancer cells.

  Journal of medicinal chemistry 20081023

• Thermal elimination of diethyldithiocarbamates and application in the synthesis of (+/-)-ferrugine.

  The Journal of organic chemistry 20081017

• NF-kappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells.

  Breast cancer research and treatment 20081001

• Human CYP2E1 mediates the formation of glycidamide from acrylamide.

  Archives of toxicology 20081001

• Inhibition of superoxide dismutase induces collagen production in cardiac fibroblasts.

  American journal of hypertension 20081001

• Enhancing effects of diethyldithiocarbamate on increase of sodium channel by sulfur dioxide derivatives in ventricular myocytes.

  Cell biology international 20080901

• Evaluation of two commercial field test kits used for screening of groundwater for arsenic in Northern India.

  The Science of the total environment 20080815

• Zinc diethyldithiocarbamate allergenicity: potential haptenation mechanisms.

  Contact dermatitis 20080801

• Improvements in cobalt determination by thermospray flame furnace atomic absorption spectrometry using an on-line derivatization strategy.

  Talanta 20080715

• Utilization of washed MSWI fly ash as partial cement substitute with the addition of dithiocarbamic chelate.

  Journal of environmental management 20080701

• Hyper-branched poly(poly(ethylene glycol)methacrylate)-grafted surfaces by photo-polymerization with iniferter for bioactive interfaces.

  Acta biomaterialia 20080701

• Enhancement of arsenic trioxide-induced apoptosis in HeLa cells by diethyldithiocarbamate or buthionine sulfoximine.

  International journal of oncology 20080701

• Contribution of aldehyde dehydrogenase 3A1 to disulfiram penetration through monolayers consisting of cultured human corneal epithelial cells.

  Biological & pharmaceutical bulletin 20080701

• Simultaneous determination of trace heavy metals in ambient aerosols by inductively coupled plasma atomic emission spectrometry after pre-concentration with sodium diethyldithiocarbamate.

  Journal of environmental science & engineering 20080701

• Allergic contact dermatitis to rubber-containing bandages in patients with leg ulcers.

  Contact dermatitis 20080601

• Copper accumulation and lipid oxidation precede inflammation and myelin lesions in N,N-diethyldithiocarbamate peripheral myelinopathy.

  Toxicology and applied pharmacology 20080515

• Application of electrospray ionization tandem mass spectrometry for the rapid and sensitive determination of cobalt in urine.

  Analytica chimica acta 20080505

• Remote renal preconditioning-induced cardioprotection: a key role of hypoxia inducible factor-prolyl 4-hydroxylases.

  Molecular and cellular biochemistry 20080501

• Chelatable zinc modulates excitability and seizure duration in the amygdala rapid kindling model.

  Epilepsy research 20080501

• Nuclear factor-kappa-B inhibitor modulates the development of opioid dependence in a mouse model of naloxone-induced opioid withdrawal syndrome.

  Behavioural pharmacology 20080501

• Acid modified diatomaceous earth--a sorbent material for thin layer chromatography.

  Journal of chromatographic science 20080401

• [AIDS: ethics and scientific investigation on human beings].

  Bulletin de la Societe de pathologie exotique (1990) 20080401

• Simultaneous speciation of inorganic selenium and antimony in water samples by electrothermal vaporization inductively coupled plasma mass spectrometry following selective cloud point extraction.

  Water research 20080201

• Uncoupling protein-2 accumulates rapidly in the inner mitochondrial membrane during mitochondrial reactive oxygen stress in macrophages.

  Biochimica et biophysica acta 20080201

• Allergic contact dermatitis as a result of diethyldithiocarbamate in a rubber cosmetic sponge.

  Contact dermatitis 20080201

• Potantial utility of disulfiram against leishmaniasis.

  The Indian journal of medical research 20080201

• Capillary electrophoretic analysis of organic pollutants.

  Methods in molecular biology (Clifton, N.J.) 20080101

• Contact allergy to p-tert-butylphenol formaldehyde resin and zinc diethyldithiocarbamate in a wet suit.

  Dermatitis : contact, atopic, occupational, drug 20080101

• Mechanisms of oxidative stress in porcine oocytes and the role of anti-oxidants.

  Reproduction, fertility, and development 20080101

• The effects of some nonsteroidal anti-inflammatory drugs on experimental induced gastric ulcers in rats.

  Inflammopharmacology 20071201

• Separation and enrichment of gold(III) from environmental samples prior to its flame atomic absorption spectrometric determination.

  Journal of hazardous materials 20071022

• Diethyldithiocarbamate injection induces transient oxidative stress in goldfish tissues.

  Chemico-biological interactions 20071020

• In vitro cell culture model for anti-cataract drug penetration studies.

  Die Pharmazie 20071001

• Role of peroxidases, thiols and Bak/Bax in tumor cell susceptibility to Cu[DEDTC]2.

  Biochemical pharmacology 20070915

• Preconcentration of trace arsenite and arsenate with titanium dioxide nanoparticles and subsequent determination by silver diethyldithiocarbamate spectrophotometric method.

  Water environment research : a research publication of the Water Environment Federation 20070901

• Delay in ICR/f rat lens opacification by the instillation of eye drops containing disulfiram and hydroxypropyl-beta-cyclodextrin inclusion complex.

  Biological & pharmaceutical bulletin 20070801

• The Nrf2 transcription factor contributes to the induction of alpha-class GST isoenzymes in liver of acute cadmium or manganese intoxicated rats: comparison with the toxic effect on NAD(P)H:quinone reductase.

  Toxicology 20070731

• A multi-element solid-phase extraction method for trace metals determination in environmental samples on Amberlite XAD-2000.

  Journal of hazardous materials 20070719

• Solid-phase extraction of Mn(II), Co(II), Ni(II), Cu(II), Cd(II) and Pb(II) ions from environmental samples by flame atomic absorption spectrometry (FAAS).

  Journal of hazardous materials 20070719

• Antioxidant enzyme inhibitors enhance peroxynitrite-induced cell death in U937 cells.

  Molecular and cellular biochemistry 20070701

• A subpopulation of Candida albicans and Candida tropicalis biofilm cells are highly tolerant to chelating agents.

  FEMS microbiology letters 20070701

• Transcriptional up-regulation of nitric oxide synthase II by nuclear factor-kappaB at rostral ventrolateral medulla in a rat mevinphos intoxication model of brain stem death.

  The Journal of physiology 20070615

• Ni uptake by a green alga. 1. Validation of equilibrium models for complexation effects.

  Environmental science & technology 20070615

• Modulation of hepatic and renal metabolism and toxicity of trichloroethylene and perchloroethylene by alterations in status of cytochrome P450 and glutathione.

  Toxicology 20070603

• Optimal reactive oxygen species concentration and p38 MAP kinase are required for coronary collateral growth.

  American journal of physiology. Heart and circulatory physiology 20070601

• Effects of epigallocatechin gallate on diethyldithiocarbamate-induced pancreatic fibrosis in rats.

  Biological & pharmaceutical bulletin 20070601

• Sorption kinetics of arsenic on laterite soil in aqueous medium.

  Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20070601

• Sodium diethyldithiocarbamate, an AIDS progression inhibitor and a copper-binding compound, has proteasome-inhibitory and apoptosis-inducing activities in cancer cells.

  International journal of molecular medicine 20070501

• Inhibition of selenium dependent glutathione peroxidase and superoxide dismutase in rats by diethyldithiocarbamate: effect of pre-administration of alpha-tocopherol.

  Indian journal of experimental biology 20070501

• Comparative investigation of N,N'-bis-(dithiocarboxy)piperazine and diethyldithiocarbamate as precipitants for Ni(II) in simulated wastewater.

  Journal of hazardous materials 20070402

• Peripheral nerve protein expression and carbonyl content in N,N-diethlydithiocarbamate myelinopathy.

  Chemical research in toxicology 20070301

• Effects of diethyldithiocarbamate (DETC) on liver injury induced by ischemia-reperfusion in rats.

  Transplantation proceedings 20070301

• Reduction enhances yields of nitric oxide trapping by iron-diethyldithiocarbamate complex in biological systems.

  Nitric oxide : biology and chemistry 20070201

• Determination of epoxides by high-performance liquid chromatography following derivatization with N,N-diethyldithiocarbamate.

  Analytical and bioanalytical chemistry 20070201

• Interventions for preventing neuropathy caused by cisplatin and related compounds.

  The Cochrane database of systematic reviews 20070124

• Adsorption of Acid Red 73 on copper dithiocarbamate precipitate-type solid wastes.

  Chemosphere 20070101

• CYP3A4 mediated in vitro metabolism of vinflunine in human liver microsomes.

  Acta pharmacologica Sinica 20070101

• Effect of magnesium deficiency on intracellular ATP levels in human lens epithelial cells.

  Biological & pharmaceutical bulletin 20070101

• Determination of zinc diethyldithiocarbamate released into artificial sweat from natural rubber latex vulcanizates by HPLC.

  Journal of chromatographic science 20070101

• [Role of Cu, Zn- and Mn-containing superoxide dismutases during the yeast Saccharomyces cerevisiae growing on ethanol and glycerol].

  Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) 20070101

• Paradoxical effects of two oximes on nitric oxide production by purified NO synthases, in cell culture and in animals.

  Nitric oxide : biology and chemistry 20070101

• Targeting of nuclear factor-kappaB and proteasome by dithiocarbamate complexes with metals.

  Current pharmaceutical design 20070101

• CYP 2E1 mutant mice are resistant to DDC-induced enhancement of MPTP toxicity.

  Journal of neural transmission. Supplementum 20070101

• Modulation of BDNF and TrkB expression in rat hippocampus in response to acute neurotoxicity by diethyldithiocarbamate.

  Neuroscience letters 20061213

• Transient and partial mitochondrial inhibition for the treatment of postresuscitation injury: getting it just right.

  Critical care medicine 20061201

• Axonal retraction and regeneration induced by N,N-diethyldithiocarbamate (DEDTC) in the central nervous system.

  The European journal of neuroscience 20061201

• Mechanism of adaptation of the vascular system to chronic changes in nitric oxide level in the organism.

  Bulletin of experimental biology and medicine 20061201

• Isoniazid-induced hepatotoxicity in rat hepatocytes of gel entrapment culture.

  Toxicology letters 20061101

• Up-regulation of cytosolic phospholipase A2alpha expression by N,N-diethyldithiocarbamate in PC12 cells; involvement of reactive oxygen species and nitric oxide.

  Toxicology and applied pharmacology 20060901

• Dithiocarbamic acid esters as anticancer agent. Part 1: 4-substituted-piperazine-1-carbodithioic acid 3-cyano-3,3-diphenyl-propyl esters.

  Bioorganic & medicinal chemistry letters 20060815

• Identification of the cytochrome P450 enzymes responsible for the omega-hydroxylation of phytanic acid.

  FEBS letters 20060710

• Antioxidant enzyme inhibitors enhance nitric oxide-induced cell death in U937 cells.

  Biochimie 20060701

• Extraction of arsenate and arsenite species from soils and sediments.

  Environmental pollution (Barking, Essex : 1987) 20060501

• Neural overexcitation and implication of NMDA and AMPA receptors in a mouse model of temporal lobe epilepsy implying zinc chelation.

  Epilepsia 20060501

• EXAFS and IR structural study of platinum-based anticancer drugs' degradation by diethyl dithiocarbamate.

  Inorganic chemistry 20060417

• The superoxide dismutase inhibitor diethyldithiocarbamate has antagonistic effects on apoptosis by triggering both cytochrome c release and caspase inhibition.

  Free radical biology & medicine 20060415

• Reactive oxygen species-mediated regulation of the Na+-H+ exchanger 1 gene expression connects intracellular redox status with cells' sensitivity to death triggers.

  Cell death and differentiation 20060401

• Suppression of survival in human SKBR3 breast carcinoma in response to metal-chelator complexes is preferential for copper-dithiocarbamate.

  Biochemical pharmacology 20060314

• Xanthine oxidase-derived free radicals directly activate rat pancreatic stellate cells.

  Journal of gastroenterology and hepatology 20060301

• Mass balance of metal species in supercritical fluid extraction using sodium diethyldithiocarbamate and dibutylammonium dibutyldithiocarbamate.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20060301

• Detoxification of dissolved SO2 (bisulfite) by terricolous mosses.

  Annals of botany 20060201

• Folic acid reverses endothelial dysfunction induced by inhibition of tetrahydrobiopterin biosynthesis.

  European journal of pharmacology 20060120

• Prolonged oxidative stress inverts the cardiac force-frequency relation: role of altered calcium handling and myofilament calcium responsiveness.

  Journal of molecular and cellular cardiology 20060101

• Evaluation of lipid-based carrier systems and inclusion complexes of diethyldithiocarbamate-iron to trap nitric oxide in biological systems.

  Magnetic resonance in medicine 20060101

• Mechanism of hepatic heme oxygenase-1 induction by isoflurane.

  Anesthesiology 20060101

• Real-time PCR: housekeeping genes in the INS-1E beta-cell line.

  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20060101

• Cytochrome P450 and Parkinson's disease: protective role of neuronal CYP 2E1 from MPTP toxicity.

  Journal of neural transmission. Supplementum 20060101

• ESR techniques for the detection of nitric oxide in vivo as an index of endothelial function.

  Pharmacological reports : PR 20060101

• Diethyldithiocarbamate inhibits in vivo Cu,Zn-superoxide dismutase and perturbs free radical processes in the yeast Saccharomyces cerevisiae cells.

  Biochemical and biophysical research communications 20051230

• Release and hemodynamic influence of nitro-glycerine-derived nitric oxide in endotoxemic rats.

  Vascular pharmacology 20051201

• Dual effects of copper-zinc superoxide dismutase.

  Biochemical and biophysical research communications 20051104

• Role of CYP2E1 in deramciclane metabolism.

  Drug metabolism and disposition: the biological fate of chemicals 20051101

• Luminescence properties of metal(II)-diethyldithiocarbamate chelate complex particles and its analytical application.

  Journal of fluorescence 20051101

• Comparison of implantation and cytotoxicity testing for initially toxic biomaterials.

  Journal of biomedical materials research. Part A 20051001

• The effects of superoxide anion generators on responses to exogenous nitric oxide and non-adrenergic, non-cholinergic nerve stimulation in rat isolated penile bulb.

  Basic & clinical pharmacology & toxicology 20050901

• The development and use of an innovative laboratory method for measuring arsenic in drinking water from western Bangladesh.

  Environmental health perspectives 20050901

• Biochemical and biophysical changes induced by fungicide sodium diethyl dithiocarbamate (SDD), in phytocystatin purified from Phaseolus mungo (Urd): a commonly used Indian legume.

  Journal of agricultural and food chemistry 20050727

• Extraction of haptens from solid products and their delivery to the skin, exemplified by dithiocarbamates from rubber gloves.

  Contact dermatitis 20050701

• Altered expression of cytochrome P450 and possible correlation with preneoplastic changes in early stage of rat hepatocarcinogenesis.

  Acta pharmacologica Sinica 20050601

• Camostat, an oral trypsin inhibitor, reduces pancreatic fibrosis induced by repeated administration of a superoxide dismutase inhibitor in rats.

  Journal of gastroenterology and hepatology 20050601

• Purification and characterization of polyphenol oxidase from nettle (Urtica dioica L.) and inhibitory effects of some chemicals on enzyme activity.

  Journal of enzyme inhibition and medicinal chemistry 20050601

• Oxidative stress mediates drug-induced hepatotoxicity in rats: a possible role of DNA fragmentation.

  Toxicology 20050330

• Diethyldithiocarbamate inhibits iNOS expression in human lens epithelial cells stimulated by IFN-gamma and LPS.

  Acta pharmacologica Sinica 20050301

• Influences of DTC and zinc supplementation on the cellular response restoration in restrained mice.

  Journal of veterinary science 20050301

• c-Src and hydrogen peroxide mediate transforming growth factor-beta1-induced smooth muscle cell-gene expression in 10T1/2 cells.

  Arteriosclerosis, thrombosis, and vascular biology 20050201

• 9,10-Phenanthraquinone in diesel exhaust particles downregulates Cu,Zn-SOD and HO-1 in human pulmonary epithelial cells: intracellular iron scavenger 1,10-phenanthroline affords protection against apoptosis.

  Free radical biology & medicine 20050201

• Purification and characterization of phenoloxidase from clam Ruditapes philippinarum.

  Fish & shellfish immunology 20050101

• Effect of copper and diethyldithiocarbamate combination therapy on the macular mouse, an animal model of Menkes disease.

  Journal of inherited metabolic disease 20050101

• Superoxide mediates sympathoexcitation in heart failure: roles of angiotensin II and NAD(P)H oxidase.

  Circulation research 20041029

• Hippocampal CA3-region is crucial for acquisition and memory consolidation in Morris water maze task in mice.

  Behavioural brain research 20041005

• Involvement of cytochrome P450 2E1 in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease.

  Journal of neurochemistry 20041001

• An ocular drug delivery system containing zinc diethyldithiocarbamate and HPbetaCD inclusion complex--corneal permeability, anti-cataract effects and mechanism studies.

  The Journal of pharmacy and pharmacology 20041001

• High-resolution mapping of neuronal activity by thallium autometallography.

  NeuroImage 20041001

• Diethyldithiocarbamate can induce two different type of death: apoptosis and necrosis mediating the differential MAP kinase activation and redox regulation in HL60 cells.

  Molecular and cellular biochemistry 20041001

• N,N-diethyldithiocarbamate produces copper accumulation, lipid peroxidation, and myelin injury in rat peripheral nerve.

  Toxicological sciences : an official journal of the Society of Toxicology 20040901

• Vasomotor responses in MnSOD-deficient mice.

  American journal of physiology. Heart and circulatory physiology 20040901

• Effect of cytochrome P450 inhibitors (diethyl dithiocarbamate, ketoconazole and grapefruit juice) on the pharmacokinetics of all-trans-retinoic acid.

  Farmaco (Societa chimica italiana : 1989) 20040901

• Effects of local administrations of tempol and diethyldithio-carbamic on peripheral nerve activity.

  Hypertension (Dallas, Tex. : 1979) 20040801

• Endothelium- and nitric oxide-dependent vasorelaxing activities of gamma-butyrobetaine esters: possible link to the antiischemic activities of mildronate.

  European journal of pharmacology 20040708

• Influence of selected inhibitors on the metabolism of the styrene metabolite 4-vinylphenol in wild-type and CYP2E1 knockout mice.

  Journal of toxicology and environmental health. Part A 20040625

• Radiation protection by diethyldithiocarbamate: protection of membrane and DNA in vitro and in vivo against gamma-radiation.

  Journal of radiation research 20040601

• Vibrio cholerae periplasmic superoxide dismutase: isolation of the gene and overexpression of the protein.

  Journal of biotechnology 20040408

• Inducible superoxide dismutase 1 aggregation in transgenic amyotrophic lateral sclerosis mouse fibroblasts.

  Journal of cellular biochemistry 20040401

• Cyp1a2 protects against reactive oxygen production in mouse liver microsomes.

  Free radical biology & medicine 20040301

• Influence of polyethylene-glycol-superoxide dismutase and combined depletion and repletion of antioxidants on nitrergic relaxation in the pig gastric fundus.

  European journal of pharmacology 20040220

• Chelation of synaptic zinc induces overexcitation in the hilar mossy cells of the rat hippocampus.

  Neuroscience letters 20040123

• The induction of amyloid precursor protein and alpha-synuclein in rat hippocampal astrocytes by diethyldithiocarbamate and copper with or without glutathione.

  Toxicology letters 20040115

• Dihydrolipoic acid lowers the redox activity of transition metal ions but does not remove them from the active site of enzymes.

  Redox report : communications in free radical research 20040101

• Benzene metabolism in human lung cell lines BEAS-2B and A549 and cells overexpressing CYP2F1.

  Journal of biochemical and molecular toxicology 20040101

• Disulfiram metabolites permanently inactivate the human multidrug resistance P-glycoprotein.

  Molecular pharmaceutics 20040101

• Sulfallate.

  Report on carcinogens : carcinogen profiles 20040101

• Nitric oxide inhibits superoxide-stimulated urea permeability in the rat inner medullary collecting duct.

  American journal of physiology. Renal physiology 20031201

• Decreased survival of prostate cancer cells in vitro by combined treatment of heat and an antioxidant inhibitor diethyldithiocarbamate (DDC).

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20031101

• Diethyldithiocarbamate inhibits the catalytic activity of xanthine oxidase.

  FEBS letters 20030911

• Inhibition of nitrification in soil by metal diethyldithiocarbamates.

  Journal of environmental sciences (China) 20030901

• EPR investigation of in vivo inhibitory effect of guanidine compounds on nitric oxide production in rat tissues.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20030901

• Detection and description of various stores of nitric oxide store in vascular wall.

  Bulletin of experimental biology and medicine 20030901

• Effects of monoamine oxidase inhibitors on the diethyldithiocarbamate-induced enhancement of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in C57BL/6 mice.

  Journal of neural transmission (Vienna, Austria : 1996) 20030801

• Recovery of motor function and dopaminergic parameters in a mouse model of Parkinson's disease induced by co-administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and diethyldithiocarbamate.

  Journal of neural transmission (Vienna, Austria : 1996) 20030801

• Involvement of the hippocampal CA3-region in acquisition and in memory consolidation of spatial but not in object information in mice.

  Neurobiology of learning and memory 20030701

• Increased renal medullary H2O2 leads to hypertension.

  Hypertension (Dallas, Tex. : 1979) 20030701

• Diethyldithiocarbamate-induced cytotoxicity and apoptosis in leukemia cell lines.

  Biological & pharmaceutical bulletin 20030701

• Oxidation of 4-hydroxy-2-nonenal by succinic semialdehyde dehydrogenase (ALDH5A).

  Journal of neurochemistry 20030701

• Detection and evaluation of NO stores in awake rats.

  Bulletin of experimental biology and medicine 20030701

• Strong hg(II) complexation in municipal wastewater effluent and surface waters.

  Environmental science & technology 20030615

• The chemical reactivity of BNP7787 and its metabolite mesna with the cytostatic agent cisplatin: comparison with the nucleophiles thiosulfate, DDTC, glutathione and its disulfide GSSG.

  Cancer chemotherapy and pharmacology 20030601

• Parenteral N,N-diethyldithiocarbamate produces segmental demyelination in the rat that is not dependent on cysteine carbamylation.

  Toxicology and applied pharmacology 20030601

• Dextromethorphan prevents the diethyldithiocarbamate enhancement of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in mice.

  Brain research 20030530

• Glutathione depletion increases nitric oxide-induced oxidative stress in primary rat hepatocyte cultures: involvement of low-molecular-weight iron.

  Free radical biology & medicine 20030515

• Fos protein expression following acute administration of diethyldithiocarbamate in rats.

  Neuroscience letters 20030515

• Mechanisms of the protective action of diethyldithiocarbamate-iron complex on acute cardiac allograft rejection.

  American journal of physiology. Heart and circulatory physiology 20030501

• Contribution of CYP2E1 to N-methyl-2-pyrrolidone metabolism.

  Archives of toxicology 20030501

• Triple vs. quadruple therapy for treating Helicobacter pylori infection: a meta-analysis.

  Alimentary pharmacology & therapeutics 20030501

• Inhibition of high K+-evoked gamma-aminobutyric acid release by sodium nitroprusside in rat hippocampus.

  European journal of pharmacology 20030425

• Tissue-engineered cartilage using an injectable and in situ gelable thermoresponsive gelatin: fabrication and in vitro performance.

  Tissue engineering 20030401

• Calretinin/PSA-NCAM immunoreactive granule cells after hippocampal damage produced by kainic acid and DEDTC treatment in mouse.

  Brain research 20030321

• Truffle thio-flavours reversibly inhibit truffle tyrosinase.

  FEMS microbiology letters 20030314

• Identification of the hydroxyl radical and other reactive oxygen species in human neutrophil granulocytes exposed to a fragment of the amyloid beta peptide.

  Free radical research 20030301

• Inhibition of Japanese encephalitis virus infection by diethyldithiocarbamate is independent of its antioxidant potential.

  Antiviral chemistry & chemotherapy 20030301

• Renal sympathetic nerve responses to tempol in spontaneously hypertensive rats.

  Hypertension (Dallas, Tex. : 1979) 20030201

• The British standard series of contact dermatitis allergens: validation in clinical practice and value for clinical governance.

  The British journal of dermatology 20030201

• Chemical modifications to study mutations that affect the ability of the general base (E268) to function in human liver mitochondrial aldehyde dehydrogenase.

  Chemico-biological interactions 20030201

• Role of superoxide anion in pancreatic islet blood flow regulation in anesthetized rats.

  European journal of pharmacology 20030110

• Zinc chelation during non-lesioning overexcitation results in neuronal death in the mouse hippocampus.

  Neuroscience 20030101

• Apoptosis in growing hair follicles following gamma-irradiation and application for the evaluation of radioprotective agents.

  In vivo (Athens, Greece) 20030101

• Kinetics of increased generation of (.)NO in endotoxaemic rats as measured by EPR.

  Acta biochimica Polonica 20030101

• DDTC, a metabolite of disulfiram, reduces the stimulating effect on ethanol's locomotor activity in mice.

  Psychopharmacology bulletin 20030101

• Fluorescence microplate assay for the detection of oxidative burst products in tobacco cell suspensions using 2',7'-dichlorofluorescein.

  Methods in cell science : an official journal of the Society for In Vitro Biology 20030101

• Intracellular superoxide induces apoptosis in VSMCs: role of mitochondrial membrane potential, cytochrome C and caspases.

  Apoptosis : an international journal on programmed cell death 20021201

• Effects of thymomimetic drugs and zinc supplementation on the cellular immune response in hydrocortisone-suppressed mice.

  Journal of veterinary medicine. B, Infectious diseases and veterinary public health 20021201

• Angiotensin II induces a rapid and transient increase of reactive oxygen species.

  Antioxidants & redox signaling 20021201

• Inhibition of the microsomal metabolism of 1,8-cineole in the common brushtail possum (Trichosurus vulpecula) by terpenes and other chemicals.

  Xenobiotica; the fate of foreign compounds in biological systems 20021201

• Measurement of ascorbic acid (vitamin C) induced hydroxyl radical generation in household drinking water.

  Free radical research 20021201

• Do mast cells play any role in the pathogenesis of experimental pancreatic fibrosis in rats?

  Pancreas 20021101

• Postnatal maturation in nitric oxide-induced pulmonary artery relaxation involving cyclooxygenase-1 activity.

  American journal of physiology. Lung cellular and molecular physiology 20021001

• Superoxide contributes to vascular dysfunction in mice that express human renin and angiotensinogen.

  American journal of physiology. Heart and circulatory physiology 20021001

• Effect of the inhibition of the metabolism of 4-vinylphenol on its hepatotoxicity and pneumotoxicity in rats and mice.

  Toxicology 20020930

• Copper uptake is required for pyrrolidine dithiocarbamate-mediated oxidation and protein level increase of p53 in cells.

  The Biochemical journal 20020801

• Modulation of heat-induced cell death in PC-3 prostate cancer cells by the antioxidant inhibitor diethyldithiocarbamate.

  BJU international 20020801

• Evaluation of the cytotoxicity of polyetherurethane (PU) film containing zinc diethyldithiocarbamate (ZDEC) on various cell lines.

  Yonsei medical journal 20020801

• [Photometric determination of cobalt by the formation of a multi-ligand complex of Co(II)-C16H16N2S2O2-DEA].

  Guang pu xue yu guang pu fen xi = Guang pu 20020801

• Increased NADPH oxidase activity, gp91phox expression, and endothelium-dependent vasorelaxation during neointima formation in rabbits.

  Circulation research 20020712

• Effects of the dithiocarbamate fungicide propineb in primary neuronal cell cultures and skeletal muscle cells of the rat.

  Archives of toxicology 20020701

• Functional analysis of the copper-dependent quercetin 2,3-dioxygenase. 1. Ligand-induced coordination changes probed by X-ray crystallography: inhibition, ordering effect, and mechanistic insights.

  Biochemistry 20020625

• Sleep impairment by diethyldithiocarbamate in rat. Protective effects of pre-conditioning and antioxidants.

  Brain research 20020607

• Production of superoxide through NADH oxidase in thick ascending limb of Henle's loop in rat kidney.

  American journal of physiology. Renal physiology 20020601

• EPR characterization of the mononuclear Cu-containing Aspergillus japonicus quercetin 2,3-dioxygenase reveals dramatic changes upon anaerobic binding of substrates.

  European journal of biochemistry 20020601

• Change of Cu,Zn-superoxide dismutase activity of guinea pig lung in experimental asthma.

  Free radical research 20020601

• The effects of ebselen on cisplatin and diethyldithiocarbamate (DDC) cytotoxicity in rat hippocampal astrocytes.

  Toxicology letters 20020528

• Production of interleukin-6 by skeletal myotubes: role of reactive oxygen species.

  American journal of respiratory cell and molecular biology 20020501

• Microglia activation and cell death in response to diethyl-dithiocarbamate acute administration.

  The Journal of comparative neurology 20020429

• Peripheral 5-HT(2A)-receptor-mediated formation of an inhibitor of atrial natriuretic peptide binding involves inflammation.

  European journal of pharmacology 20020405

• Concurrent administration of diethyldithiocarbamate and 4-methylpyrazole enhances ethanol-induced locomotor activity: the role of brain ALDH.

  Psychopharmacology 20020401

• Effects of N-acetylcysteine in an esophageal carcinogenesis model in rats treated with diethylnitrosamine and diethyldithiocarbamate.

  International journal of cancer 20020401

• Reduction of toxic metabolite formation of acetaminophen.

  Biochemical and biophysical research communications 20020308

• Diethyldithiocarbamate inhibition of galactosamine-induced hepatitis in rats.

  Pharmacological research 20020301

• In vivo inhibition of selenium dependent glutathione peroxidase and superoxide dismutase in rats by diethyldithiocarbamate.

  Indian journal of experimental biology 20020301

• Palmitate-induced apoptosis in neonatal cardiomyocytes is not dependent on the generation of ROS.

  American journal of physiology. Heart and circulatory physiology 20020201

• Nitric oxide blockade enhances renal responses to superoxide dismutase inhibition in dogs.

  Hypertension (Dallas, Tex. : 1979) 20020201

• Influence of antioxidant depletion on nitrergic relaxation in the pig gastric fundus.

  British journal of pharmacology 20020201

• Increased renal medullary oxidative stress produces hypertension.

  Hypertension (Dallas, Tex. : 1979) 20020201

• Effect of a high salt diet on microvascular antioxidant enzymes.

  Journal of vascular research 20020101

• [Poisoning by chromium and its long lasting detoxication].

  Medicina (Kaunas, Lithuania) 20020101

• Advanced spin trapping of vascular nitric oxide using colloid iron diethyldithiocarbamate.

  Methods in enzymology 20020101

• Influence of diethyldithiocarbamate on the activity of ecto-ATPase in lymphocytes of rats: ex vivo studies.

  Polish journal of pharmacology 20020101

• Sulfallate.

  Report on carcinogens : carcinogen profiles 20020101

• Effects of vanilloid receptor agonists and antagonists on gastric antral ulcers in rats.

  European journal of pharmacology 20011207

• Oxidative stress enhances the production and actions of adenosine in the kidney.

  American journal of physiology. Regulatory, integrative and comparative physiology 20011201

• ET-1 stimulates pulmonary arterial smooth muscle cell proliferation via induction of reactive oxygen species.

  American journal of physiology. Lung cellular and molecular physiology 20011101

• Nitric oxide donors retard wound healing in cultured rabbit gastric epithelial cell monolayers.

  American journal of physiology. Gastrointestinal and liver physiology 20011101

• Nitric oxide and iron overload. Limitations of ESR detection by DETC.

  Toxicology 20011030

• Use of the chemiluminescent probe lucigenin to monitor the production of the superoxide anion radical in a recombinant Aspergillus niger (B1-D).

  Biotechnology and bioengineering 20011020

• Superoxide levels and function of cerebral blood vessels after inhibition of CuZn-SOD.

  American journal of physiology. Heart and circulatory physiology 20011001

• Quantification of copper in biological materials by use of electron spin resonance.

  Clinical chemistry 20011001

• Volumetric and horseradish peroxidase tracing analysis of rat olfactory bulb following reversible olfactory nerve lesions.

  Chemical senses 20011001

• Chronic and cyclical neuronal loss in hippocampal slice cultures following transient inhibition of the type 1 isoform of superoxide dismutase.

  Brain research 20010921

• Effects of diethyldithiocarbamate on proliferation, redifferention, and apoptosis in human hepatoma cells.

  Acta pharmacologica Sinica 20010901

• Lipopolysaccharide and interferon-gamma-induced nitric oxide production and protein oxidation in mouse peritoneal macrophages are affected by glutathione peroxidase-1 gene knockout.

  Free radical biology & medicine 20010815

• Superoxide-mediated early oxidation and activation of ASK1 are important for initiating methylglyoxal-induced apoptosis process.

  Free radical biology & medicine 20010815

• Patch testing discordance alert: false-negative findings with rubber additives and fragrances.

  Journal of the American Academy of Dermatology 20010801

• 2,5-Di-t-butyl-1,4-benzohydroquinone (BHQ) inhibits vascular L-type Ca(2+) channel via superoxide anion generation.

  British journal of pharmacology 20010801

• Pesticides directly accelerate the rate of alpha-synuclein fibril formation: a possible factor in Parkinson's disease.

  FEBS letters 20010706

• Pituitary adenylyl cyclase-activating peptides and alpha-amidation in olfactory neurogenesis and neuronal survival in vitro.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010701

• Activation of the nuclear factor-kappaB is a key event in brain tolerance.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010701

• Inhibition of cytochrome P450 2E1 induces an increase in extracellular dopamine in rat substantia nigra: a new metabolic pathway?

  Synapse (New York, N.Y.) 20010615

• The NF-kappaB inhibitor diethyldithiocarbamate (DDTC) increases brain cell death in a transient middle cerebral artery occlusion model of ischemia.

  Brain research bulletin 20010601

• Experimental evidence suggesting that nitric oxide diffuses from tissue into blood but not from blood into tissue.

  Biochimica et biophysica acta 20010531

• Antioxidants inhibit JNK and p38 MAPK activation but not ERK 1/2 activation by angiotensin II in rat aortic smooth muscle cells.

  Hypertension research : official journal of the Japanese Society of Hypertension 20010501

• Placental superoxide is increased in pre-eclampsia.

  Placenta 20010401

• Rat liver microsomal lipid peroxidation produced during the oxidative metabolism of ethacrynic acid.

  Pharmacology & toxicology 20010401

• Enhanced superoxide anion formation in vascular tissues from spontaneously hypertensive and desoxycorticosterone acetate-salt hypertensive rats.

  Journal of hypertension 20010401

• On-line preconcentration system using a packed-bed filter for the determination of lead in tap water by inductively coupled plasma atomic emission spectrometry with ultrasonic nebulization.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20010301

• Coprecipitation of trace metal ions in water with bismuth(III) diethyldithiocarbamate for an electrothermal atomic absorption spectrometric determination.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20010301

• Sodium nitroprusside-induced seizures and adenosine release in rat hippocampus.

  European journal of pharmacology 20010216

• Effects of sodium diethyldithiocarbamate on type II pulmonary epithelial cells in vitro.

  Journal of toxicology and environmental health. Part A 20010209

• Metabolism of a disulfiram metabolite, S-methyl N,N-diethyldithiocarbamate, by flavin monooxygenase in human renal microsomes.

  Drug metabolism and disposition: the biological fate of chemicals 20010201

• Production and actions of superoxide in the renal medulla.

  Hypertension (Dallas, Tex. : 1979) 20010201

• Overview--in vitro inhibition of aldehyde dehydrogenase by disulfiram and metabolites.

  Chemico-biological interactions 20010130

• In vivo inhibition of aldehyde dehydrogenase by disulfiram.

  Chemico-biological interactions 20010130

• Preventive effect of diethyldithiocarbamate on selenite-induced opacity in cultured rat lenses.

  Ophthalmic research 20010101

• Oxidative stress regulates collagen synthesis and matrix metalloproteinase activity in cardiac fibroblasts.

  American journal of physiology. Cell physiology 20010101

• Study on free radicals and pancreatic fibrosis--pancreatic fibrosis induced by repeated injections of superoxide dismutase inhibitor.

  Pancreas 20010101

• S-methyl-N,N-diethylthiocarbamate sulfoxide elicits neuroprotective effect against N-methyl-D-aspartate receptor-mediated neurotoxicity.

  Journal of biomedical science 20010101

• Oxygen metabolites in immune- stimulated ion transport in rat colon: modulation by taurine.

  Digestion 20010101

• Combined pulmonary toxicity of cadmium chloride and sodium diethyldithiocarbamate.

  Journal of applied toxicology : JAT 20010101

• Modification of radiation response in mice by Panax ginseng and diethyldithiocarbamate.

  In vivo (Athens, Greece) 20010101

• A Genetically engineered cell-based system for detecting metabolism-mediated toxicity.

  Alternatives to laboratory animals : ATLA 20010101

• Redox regulation of p53 during hypoxia.

  Oncogene 20000810

• Protective role of copper, zinc superoxide dismutase against UVB-induced injury of the human keratinocyte cell line HaCaT.

  The Journal of investigative dermatology 20000301

• Metabolism of benzene in human liver microsomes: individual variations in relation to CYP2E1 expression.

  Archives of toxicology 19990201

• Antiviral oligo- and polyribonucleotides containing selected triazolo[2,3-a]purines.

  Journal of medicinal chemistry 19981203

• Activity of disulfiram (bis(diethylthiocarbamoyl)disulphide) and ditiocarb (diethyldithiocarbamate) against metronidazole-sensitive and -resistant Trichomonas vaginalis and Tritrichomonas foetus.

  The Journal of antimicrobial chemotherapy 19981201

• The detection of cytochrome P450 2E1 and its catalytic activity in rat testis.

  Biochemical and biophysical research communications 19980529

• Protective effect of diethyldithiocarbamate pretreatment on chromium (VI)-induced cytotoxicity and lipid peroxidation in primary cultures of rat hepatocytes.

  The Journal of veterinary medical science 19980101

• Zinc ejection as a new rationale for the use of cystamine and related disulfide-containing antiviral agents in the treatment of AIDS.

  Journal of medicinal chemistry 19970620

• Examination of purported probes of human CYP2B6.

  Pharmacogenetics 19970601

• Involvement of cytochrome P4502E1 in the toxicity of dichloropropanol to rat hepatocyte cultures.

  Toxicology 19970328

• Effect of diethyldithiocarbamate on Cryptosporidium parvum infection in immunosuppressed rats.

  The Journal of parasitology 19960201

• Differences in rates of benzene metabolism correlate with observed genotoxicity.

  Toxicology and applied pharmacology 19960101

• Drug interaction effects on antitumour drugs (XV): Disulfiram as protective agent against cyclophosphamide-induced urotoxicity without compromising antitumour activity in mice.

  Pharmacology & toxicology 19940101

• Effects of inhibition of catalase and superoxide dismutase activity on antioxidant enzyme mRNA levels.

  The American journal of physiology 19931201

• Regulation of cytochrome P450 2B1/2 genes by diallyl sulfone, disulfiram, and other organosulfur compounds in primary cultures of rat hepatocytes.

  Biochemical pharmacology 19930609

• Dominant role of cytochrome P-450 2E1 in human hepatic microsomal oxidation of the CFC-substitute 1,1,1,2-tetrafluoroethane.

  Drug metabolism and disposition: the biological fate of chemicals 19920101

• Synthesis and anti-HIV-1 activity of 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-on e (TIBO) derivatives. 2.

  Journal of medicinal chemistry 19911101

• Nephrotoxicity of paracetamol in the rat--mechanistic and therapeutic aspects.

  Journal of applied toxicology : JAT 19910401

• Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects.

  Chemical research in toxicology 19910101

• Cellular response after mobilization of metals by diethyldithiocarbamate in rat hepatocyte cultures.

  Toxicology 19901217

• Inhibition of HIV progression by dithiocarb. German DTC Study Group.

  Lancet (London, England) 19900324

• Methamphetamine-induced neuronal damage: a possible role for free radicals.

  Neuropharmacology 19891001

• Stress by restraining potentiates morphine catalepsy in rats.

  Experientia 19851215

• In-vitro inhibition of LAV/HTLV-III infected lymphocytes by dithiocarb and inosine pranobex.

  Lancet (London, England) 19851201

• Dose-response characteristics of various peptides with growth hormone-releasing activity in the unanesthetized male rat.

  Endocrinology 19850701

• The generation and regulation of human T lymphocytes by Imuthiol. Evidence from an in vitro differentiation induction system.

  International journal of immunopharmacology 19850101

• In vitro interaction of dithiocarb with rat liver glutathione S-transferases.

  Pharmacological research communications 19840201

• Central action of narcotic analgesics. Part III. The role of endogenous noradrenaline in hyperactivity induced by morphine or fentanyl in mice.

  Polish journal of pharmacology and pharmacy 19780101