148741-30-4 | (2E)-2-Cyano-3-(3,5-di-tert-butyl-4-hydroxyphenyl)prop-2-enethioamide

Packsize	Purity	Availability	Price	Discounted Price
1mg	95%	in stock	$16.00	$11.00
5mg	95%	in stock	$28.00	$19.00
10mg	95%	in stock	$38.00	$26.00
25mg	95%	in stock	$58.00	$40.00
100mg	95%	in stock	$123.00	$86.00
250mg	95%	in stock	$208.00	$145.00

Description

• Catalog Number: AA73887
• Chemical Name: (2E)-2-Cyano-3-(3,5-di-tert-butyl-4-hydroxyphenyl)prop-2-enethioamide
• CAS Number: 148741-30-4
• Molecular Formula: C18H24N2OS
• Molecular Weight: 316.461
• MDL Number: MFCD00236450
• SMILES: N#CC(=Cc1cc(c(c(c1)C(C)(C)C)O)C(C)(C)C)C(=S)N

Computed Properties

• Complexity: 477
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 22
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 4
• XLogP3: 4.7

Literature

• Ligand-independent activation of the arylhydrocarbon receptor by ETK (Bmx) tyrosine kinase helps MCF10AT1 breast cancer cells to survive in an apoptosis-inducing environment.

  Biological chemistry 20111001

• Reciprocal regulation of 17beta-estradiol, interleukin-6 and interleukin-8 during growth and progression of epithelial ovarian cancer.

  Cytokine 20090601

• Comparison of delphinidin, quercetin and (-)-epigallocatechin-3-gallate as inhibitors of the EGFR and the ErbB2 receptor phosphorylation.

  Molecular nutrition & food research 20080701

• Interleukin-6 induces androgen responsiveness in prostate cancer cells through up-regulation of androgen receptor expression.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20010601

• Tyrphostin [correction of Tryphostin] AG879, a tyrosine kinase inhibitor: prevention of transcriptional activation of the electrophile and the aromatic hydrocarbon response elements.

  Biochemical pharmacology 20010115