14919-49-4 | 3,4'-Dihydroxyflavone

Packsize	Purity	Availability	Price	Discounted Price
1g	>97.0%(GC)	in stock	$86.00	$60.00

Description

• Catalog Number: AA74248
• Chemical Name: 3,4'-Dihydroxyflavone
• CAS Number: 14919-49-4
• Molecular Formula: C15H10O4
• Molecular Weight: 254.2375
• MDL Number: MFCD00017690
• SMILES: Oc1ccc(cc1)c1oc2ccccc2c(=O)c1O

Computed Properties

• Complexity: 393
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 19
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 3

Literature

• Design, synthesis and biological activity of flavonoid derivatives as selective agonists for neuromedin U 2 receptor.

  Bioorganic & medicinal chemistry 20141101

• A novel relationship between the radical-scavenging activity of flavonoids and enthalpy of formation revealed with Hartree-Fock computations and thermochemical deduction.

  Redox report : communications in free radical research 20120101

• 3,4-Dihydroxyflavone acts as an antioxidant and antiapoptotic agent to support bovine embryo development in vitro.

  The Journal of reproduction and development 20110201

• Use of glucuronidation fingerprinting to describe and predict mono- and dihydroxyflavone metabolism by recombinant UGT isoforms and human intestinal and liver microsomes.

  Molecular pharmaceutics 20100607

• Understanding the cardioprotective effects of flavonols: discovery of relaxant flavonols without antioxidant activity.

  Journal of medicinal chemistry 20080327

• The anti-apoptotic and anti-oxidant effect of eriodictyol on UV-induced apoptosis in keratinocytes.

  Biological & pharmaceutical bulletin 20070101

• Modulation of apoptosis in HaCaT keratinocytes via differential regulation of ERK signaling pathway by flavonoids.

  The Journal of biological chemistry 20050909