1499-55-4 | L-Glutamic acid 5-methyl ester

Packsize	Purity	Availability	Price	Discounted Price
25g	98%	in stock	$8.00	$5.00
100g	98%	in stock	$18.00	$12.00

Description

• Catalog Number: AB75116
• Chemical Name: L-Glutamic acid 5-methyl ester
• CAS Number: 1499-55-4
• Molecular Formula: C6H11NO4
• Molecular Weight: 161.15583999999998
• MDL Number: MFCD00002632
• SMILES: COC(=O)CC[C@@H](C(=O)O)N

Computed Properties

• Complexity: 157
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 5
• XLogP3: -3.4

Upstream Synthesis Route

H-Glu(OMe)-OH, also known as N-(tert-butyloxycarbonyl)-L-glutamic acid γ-t-butyl ester, is a commonly used building block in chemical synthesis. This compound plays a vital role in peptide synthesis, particularly in the creation of peptides containing glutamic acid residues.Due to its tert-butyloxycarbonyl (Boc) protective group, H-Glu(OMe)-OH is highly versatile in solid phase peptide synthesis (SPPS) as it allows for selective deprotection and coupling reactions. Additionally, the methyl ester group at the C-terminus can serve as a convenient handle for further functionalization or manipulation of the peptide chain.In organic chemistry, H-Glu(OMe)-OH is employed in the production of peptide mimetics, which are synthetic compounds designed to mimic the structure and function of natural peptides. Its strategic placement within a peptide sequence can influence the overall conformation and biological activity of the resulting peptide or peptidomimetic.Overall, H-Glu(OMe)-OH is a valuable tool for chemists engaged in peptide synthesis and drug discovery, offering precise control over peptide chain elongation and modification. Its use contributes to the development of diverse bioactive molecules with potential applications in pharmaceuticals, biotechnology, and chemical biology.