15115-60-3 | 4-Bromo-1-indanone

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$8.00	$5.00
5g	98%	in stock	$10.00	$7.00
10g	98%	in stock	$15.00	$10.00
25g	98%	in stock	$17.00	$12.00
100g	98%	in stock	$64.00	$45.00
500g	98%	in stock	$319.00	$224.00

Description

• Catalog Number: AA76434
• Chemical Name: 4-Bromo-1-indanone
• CAS Number: 15115-60-3
• Molecular Formula: C9H7BrO
• Molecular Weight: 211.0553
• MDL Number: MFCD01719772
• SMILES: O=C1CCc2c1cccc2Br
• NSC Number: 162080

Computed Properties

• Complexity: 178
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 1
• XLogP3: 2.4

Upstream Synthesis Route

4-Bromo-1-indanone is a valuable compound widely used in chemical synthesis due to its versatile reactivity and structural properties. This compound serves as a key building block in the creation of various complex organic molecules and pharmaceutical intermediates. In particular, 4-Bromo-1-indanone is commonly employed in the synthesis of indanone derivatives, which have exhibited significant biological activity in drug discovery research. Additionally, the unique bromo substituent in the molecule enables selective functionalization reactions, enabling chemists to introduce specific functional groups at the desired positions. Furthermore, 4-Bromo-1-indanone can participate in cross-coupling reactions, fluorination reactions, and other transformations to yield structurally diverse compounds with potential applications in medicinal chemistry and material science. Its role as a versatile synthetic intermediate makes 4-Bromo-1-indanone an indispensable tool for organic chemists seeking to access novel molecular scaffolds and explore new chemical space.

Literature

• Identification of a novel scaffold for allosteric inhibition of wild type and drug resistant HIV-1 reverse transcriptase by fragment library screening.

  Journal of medicinal chemistry 20110210

• Synthesis of a basket-shaped C56H38 hydrocarbon as a precursor toward an end-cap template for carbon [6,6]nanotubes.

  The Journal of organic chemistry 20100319