15291-76-6 | Ginkgolide c

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$8.00	$6.00
10mg	98%	in stock	$15.00	$11.00
25mg	98%	in stock	$19.00	$14.00
50mg	98%	in stock	$24.00	$17.00

Description

• Catalog Number: AE98166
• Chemical Name: Ginkgolide c
• CAS Number: 15291-76-6
• Molecular Formula: C20H24O11
• Molecular Weight: 440.398
• MDL Number: MFCD06642603
• SMILES: O=C1O[C@@H]2[C@@]([C@@H]1C)(O)[C@@]13[C@]4([C@@H]2O)[C@H](OC3=O)[C@@H]([C@H]([C@@]24[C@H](O1)OC(=O)[C@@H]2O)C(C)(C)C)O

Computed Properties

• Complexity: 957
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 12
• Heavy Atom Count: 31
• Hydrogen Bond Acceptor Count: 11
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 1
• XLogP3: -1.4

Literature

• Complete 1H NMR spectral analysis of ten chemical markers of Ginkgo biloba.

  Magnetic resonance in chemistry : MRC 20120801

• Spectroscopic investigation of Ginkgo biloba terpene trilactones and their interaction with amyloid peptide Abeta(25-35).

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080401

• Simultaneous determination of ginkgolides A, B, C and bilobalide in plasma by LC-MS/MS and its application to the pharmacokinetic study of Ginkgo biloba extract in rats.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080315

• Ginkgolide C inhibits platelet aggregation in cAMP- and cGMP-dependent manner by activating MMP-9.

  Biological & pharmaceutical bulletin 20071201

• Single-laboratory validation for the determination of terpene lactones in Ginkgo biloba dietary supplement crude materials and finished products by high-performance liquid chromatography with evaporative light-scattering detection.

  Journal of AOAC International 20070101

• Validation of capillary gas chromatographic method for determination of bilobalide and ginkgolides A, B, C in Ginkgo biloba dry and liquid extracts.

  Acta poloniae pharmaceutica 20070101

• LC-MS characterization of terpene lactones in plasma of experimental animals treated with Ginkgo biloba extracts Correlation with pharmacological activity.

  Journal of pharmaceutical and biomedical analysis 20060224

• [Quantitative determination of ginkgolides by liquid chromatography-electrospray mass spectrometry].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20051201

• [Applications of two-dimensional liquid chromatography coupled to mass spectrometry for the separation and identification of compounds in ginkgo biloba extracts].

  Se pu = Chinese journal of chromatography 20050101

• Preparation of a tritiated ginkgolide.

  Bioorganic & medicinal chemistry letters 20041115

• Isolation of ginkgolides A, B, C, J and bilobalide from G. biloba extracts.

  Phytochemistry 20041101

• A method for extraction and quantification of Ginkgo terpene trilactones.

  Analytical chemistry 20040801

• Ginkgolides, diterpene trilactones of Ginkgo biloba, as antagonists at recombinant alpha1beta2gamma2L GABAA receptors.

  European journal of pharmacology 20040628

• Ginkgolides and glycine receptors: a structure-activity relationship study.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20040319

• Effect of Ginkgo biloba extract on rat hepatic microsomal CYP1A activity: role of ginkgolides, bilobalide, and flavonols.

  Canadian journal of physiology and pharmacology 20040101

• An anxiolytic-like effect of Ginkgo biloba extract and its constituent, ginkgolide-A, in mice.

  Journal of natural products 20031001

• Quantitative analysis of bilobalide and ginkgolides from Ginkgo biloba leaves and Ginkgo products using (1)H-NMR.

  Chemical & pharmaceutical bulletin 20030201

• Identification and the retention index of bilobalide and ginkgolides using capillary gas chromatography.

  Journal of chromatographic science 20021001

• Ginkgolide derivatives for photolabeling studies: preparation and pharmacological evaluation.

  Journal of medicinal chemistry 20020829

• Ginkgolides: selective acetylations, translactonization, and biological evaluation.

  The Journal of organic chemistry 20020628

• Three ginkgolide hydrates from Ginkgo biloba L.: ginkgolide A monohydrate, ginkgolide C sesquihydrate and ginkgolide J dihydrate, all determined at 120 K.

  Acta crystallographica. Section C, Crystal structure communications 20020301