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Transporter targeted gatifloxacin prodrugs: synthesis, permeability, and topical ocular delivery.
Molecular pharmaceutics 20121105
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Tryptophan metabolism in breast cancers: molecular imaging and immunohistochemistry studies.
Nuclear medicine and biology 20121001
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Quantitative PET imaging of tryptophan accumulation in gliomas and remote cortex: correlation with tumor proliferative activity.
Clinical nuclear medicine 20120901
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Accurate differentiation of recurrent gliomas from radiation injury by kinetic analysis of α-11C-methyl-L-tryptophan PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20120701
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Perinatal effects on in vivo measures of human brain serotonin synthesis in adulthood: a 27-year longitudinal study.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20120601
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Increased tryptophan transport in epileptogenic dysembryoplastic neuroepithelial tumors.
Journal of neuro-oncology 20120401
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Serotonin modulates worker responsiveness to trail pheromone in the ant Pheidole dentata.
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20120301
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α-methyl-L-tryptophan: mechanisms for tracer localization of epileptogenic brain regions.
Biomarkers in medicine 20111001
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α-[¹¹C]-methyl-L-tryptophan PET for tracer localization of epileptogenic brain regions: clinical studies.
Biomarkers in medicine 20111001
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SLC6A14 (ATB0,+) protein, a highly concentrative and broad specific amino acid transporter, is a novel and effective drug target for treatment of estrogen receptor-positive breast cancer.
The Journal of biological chemistry 20110909
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Clinical and histopathologic correlates of 11C-alpha-methyl-L-tryptophan (AMT) PET abnormalities in children with intractable epilepsy.
Epilepsia 20110901
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Brain regional α-[11C]methyl-L-tryptophan trapping in medication-free patients with obsessive-compulsive disorder.
Archives of general psychiatry 20110701
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Decreased cortical serotonin in neonatal rabbits exposed to endotoxin in utero.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110201
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Amino acid derivatives are substrates or non-transported inhibitors of the amino acid transporter PAT2 (slc36a2).
Biochimica et biophysica acta 20110101
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Gender differences in alpha-[(11)C]MTrp brain trapping, an index of serotonin synthesis, in medication-free individuals with major depressive disorder: a positron emission tomography study.
Psychiatry research 20100830
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Multimodality neuroimaging in Tourette syndrome: alpha-[11C] methyl-L-tryptophan positron emission tomography and diffusion tensor imaging studies.
Journal of child neurology 20100301
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AGN-2979, an inhibitor of tryptophan hydroxylase activation, does not affect serotonin synthesis in Flinders Sensitive Line rats, a rat model of depression, but produces a significant effect in Flinders Resistant Line rats.
Neurochemistry international 20091201
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Quantification of tryptophan transport and metabolism in lung tumors using PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090301
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Alterations in brain serotonin synthesis in male alcoholics measured using positron emission tomography.
Alcoholism, clinical and experimental research 20090201
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Substrate promiscuity of the cyclic dipeptide prenyltransferases from Aspergillus fumigatus ( section sign).
Journal of natural products 20090101
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Acute citalopram has different effects on regional 5-HT synthesis in FSL, FRL, and SDP rats: an autoradiographic evaluation.
Brain research bulletin 20081022
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Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy.
The Biochemical journal 20080915
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Alpha-methyl-l-tryptophan positron emission tomography in epilepsy with cortical developmental malformations.
Pediatric neurology 20080901
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Correlation between serotonin synthesis and 5-HT1A receptor binding in the living human brain: a combined alpha-[11C]MT and [18F]MPPF positron emission tomography study.
NeuroImage 20080815
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Alpha-[11C]methyl-L-tryptophan uptake in patients with periventricular nodular heterotopia and epilepsy.
Epilepsia 20080501
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An index of 5-HT synthesis changes during early antidepressant treatment: alpha-[11C]methyl-L-tryptophan PET study.
Neurochemistry international 20080101
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Acute flesinoxan treatment produces a different effect on rat brain serotonin synthesis than chronic treatment: an alpha-methyl-l-tryptophan autoradiographic study.
Neurochemistry international 20071201
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In vivo measurements of brain trapping of C-labelled alpha-methyl-L-tryptophan during acute changes in mood states.
Journal of psychiatry & neuroscience : JPN 20071101
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5-Hydroxy-L-[beta-11C]tryptophan versus alpha-[11C]methyl-L-tryptophan for positron emission tomography imaging of serotonin synthesis capacity in the rhesus monkey brain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070401
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Assessment of progression and treatment response of optic pathway glioma with positron emission tomography using alpha-[(11)C]methyl-L-tryptophan.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20070101
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Cortical trapping of alpha-[(11)C]methyl-l-tryptophan, an index of serotonin synthesis, is lower in females than males.
NeuroImage 20061115
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alpha-[11C]Methyl-L-tryptophan trapping in the orbital and ventral medial prefrontal cortex of suicide attempters.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20060401
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Chronic buspirone treatment normalizes regional serotonin synthesis in the olfactory bulbectomized rat brain: an autoradiographic study.
Brain research bulletin 20060331
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In vivo uptake and metabolism of alpha-[11C]methyl-L-tryptophan in human brain tumors.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20060301
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BeWo trophoblasts are unable to control replication of Toxoplasma gondii, even in the presence of exogenous IFN-gamma.
Placenta 20060101
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Brain regional alpha-[11C]methyl-L-tryptophan trapping correlates with post-mortem tissue serotonin content and [11C]5-hydroxytryptophan accumulation.
The international journal of neuropsychopharmacology 20051201
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Increasing blood oxygen increases an index of 5-HT synthesis in human brain as measured using alpha-[(11)C]methyl-L-tryptophan and positron emission tomography.
Neurochemistry international 20051201
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The tryptophan hydroxylase activation inhibitor, AGN-2979, decreases regional 5-HT synthesis in the rat brain measured with alpha-[14C]methyl-L-tryptophan: an autoradiographic study.
Brain research bulletin 20051015
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Stability of alpha-[11C]methyl-L-tryptophan brain trapping in healthy male volunteers.
European journal of nuclear medicine and molecular imaging 20051001
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Chronic administration of citalopram in olfactory bulbectomy rats restores brain 5-HT synthesis rates: an autoradiographic study.
Psychopharmacology 20050601
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Serotonin synthesis by two distinct enzymes in Drosophila melanogaster.
Archives of insect biochemistry and physiology 20050501
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Epilepsy surgery outcome in children with tuberous sclerosis complex evaluated with alpha-[11C]methyl-L-tryptophan positron emission tomography (PET).
Journal of child neurology 20050501
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Octopamine and experience-dependent modulation of aggression in crickets.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20050209
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Selective 5-HT1B receptor agonist reduces serotonin synthesis following acute, and not chronic, drug administration: results of an autoradiographic study.
Neurochemistry international 20050201
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Significance of abnormalities in developmental trajectory and asymmetry of cortical serotonin synthesis in autism.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20050101
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Effects of pentadecapeptide BPC157 on regional serotonin synthesis in the rat brain: alpha-methyl-L-tryptophan autoradiographic measurements.
Life sciences 20041203
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A simplified autoradiographic method with alpha-[14C]methyl-tryptophan to measure serotonin synthesis rate in the rat brain.
Nuclear medicine and biology 20041101
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Measurement of brain regional alpha-[11C]methyl-L-tryptophan trapping as a measure of serotonin synthesis in medication-free patients with major depression.
Archives of general psychiatry 20040601
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Effects of desipramine on regional serotonin synthesis in the rat brain: acute and chronic autoradiographic studies.
Neurochemistry international 20031201
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Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase.
Nature medicine 20031001
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Tumors hijack fetal enzyme, escape killer T cells.
Nature medicine 20031001
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Alpha-methyl-L-tryptophan PET detects epileptogenic cortex in children with intractable epilepsy.
Neurology 20030325
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Alpha-[11C] methyl-L-tryptophan and glucose metabolism in patients with temporal lobe epilepsy.
Neurology 20030311
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Sex differences of brain serotonin synthesis in patients with irritable bowel syndrome using alpha-[11C]methyl-L-tryptophan, positron emission tomography and statistical parametric mapping.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20030301
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alpha-[11C]-Methyl-L-tryptophan PET identifies the epileptogenic tuber and correlates with interictal spike frequency.
Epilepsy research 20030101
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Serotonin synthesis and its light-dark variation in the rat retina.
Journal of neurochemistry 20021101
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The inhibition of tryptophan hydroxylase, not protein synthesis, reduces the brain trapping of alpha-methyl-L-tryptophan: an autoradiographic study.
Neurochemistry international 20020601
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Alpha[11C] methyl-L-typtophan positron emission tomography in patients with alternating hemiplegia of childhood.
Journal of child neurology 20020401
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Effects of serotine receptors agonists, TFMPP and CGS12066B, on regional serotonin synthesis in the rat brain: an autoradiographic study.
Journal of neurochemistry 20020301
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Localizing value of alpha-methyl-L-tryptophan PET in intractable epilepsy of neocortical origin.
Neurology 20011113
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Evaluation and application of liquid chromatographic columns coated with 'intelligent' ligands: (I) acylcarnitine column.
Journal of chromatography. A 20010921
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Study of the brain serotonergic system with labeled alpha-methyl-L-tryptophan.
Journal of neurochemistry 20010901
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Labelled alpha-methyl-L-tryptophan as a tracer for the study of the brain serotonergic system.
Journal of psychiatry & neuroscience : JPN 20010901
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Effects of selective 5-HT1A receptor antagonists on regional serotonin synthesis in the rat brain: an autoradiographic study with alpha-[14C]methyl-L-tryptophan.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20010601
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Brain Regional alpha-[11C]methyl-L-tryptophan trapping in impulsive subjects with borderline personality disorder.
The American journal of psychiatry 20010501
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1-Methyl-DL-tryptophan, beta-(3-benzofuranyl)-DL-alanine (the oxygen analog of tryptophan), and beta-[3-benzo(b)thienyl]-DL-alanine (the sulfur analog of tryptophan) are competitive inhibitors for indoleamine 2,3-dioxygenase.
Archives of biochemistry and biophysics 19911201
