1538-75-6 | Trimethylacetic anhydride

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$26.00	$18.00
25g	98%	in stock	$34.00	$24.00
100g	98%	in stock	$74.00	$52.00
500g	98%	in stock	$251.00	$176.00

Description

• Catalog Number: AB46892
• Chemical Name: Trimethylacetic anhydride
• CAS Number: 1538-75-6
• Molecular Formula: C10H18O3
• Molecular Weight: 186.2481
• MDL Number: MFCD00008842
• SMILES: O=C(C(C)(C)C)OC(=O)C(C)(C)C

Computed Properties

• Complexity: 191
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• XLogP3: 2.7

Literature

• A new method for production of chiral 2-aryl-2-fluoropropanoic acids using an effective kinetic resolution of racemic 2-aryl-2-fluoropropanoic acids.

  Molecules (Basel, Switzerland) 20120614

• [Development of novel methods for preparing chiral non-steroidal anti-inflammatory drugs (NSAIDs) by asymmetric esterification].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20120101

• (R)-(+)-N-methylbenzoguanidine ((R)-NMBG) catalyzed kinetic resolution of racemic secondary benzylic alcohols with free carboxylic acids by asymmetric esterification.

  Organic & biomolecular chemistry 20111021

• Kinetic resolution of racemic alpha-arylalkanoic acids with achiral alcohols via the asymmetric esterification using carboxylic anhydrides and acyl-transfer catalysts.

  Journal of the American Chemical Society 20100825

• Kinetic resolution of the racemic 2-hydroxyalkanoates using the enantioselective mixed-anhydride method with pivalic anhydride and a chiral acyl-transfer catalyst.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20100104

• 6-Amino-2,5-bis-(pivaloylamino)pyrimidin-4(3H)-one dihydrate.

  Acta crystallographica. Section E, Structure reports online 20090701

• Synthetic efforts for stereo structure determination of cytotoxic marine natural product pericosines as metabolites of Periconia sp. from sea hare.

  International journal of molecular sciences 20080301

• N,N-Bis(2,2-dimethyl-propano-yl)benzene-1,3-dicarbohydrazide.

  Acta crystallographica. Section E, Structure reports online 20080101

• Steric effects in the uncatalyzed and DMAP-catalyzed acylation of alcohols-quantifying the window of opportunity in kinetic resolution experiments.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20060724

• Synthesis of novel (1-alkanoyloxy-4-alkanoylaminobutylidene)-1,1-bisphosphonic acid derivatives.

  Beilstein journal of organic chemistry 20060101

• Nucleophilic acyl substitutions of anhydrides with protic nucleophiles catalyzed by amphoteric, oxomolybdenum species.

  The Journal of organic chemistry 20050218

• Measurement of N7-(2'-hydroxyethyl)guanine in human DNA by gas chromatography electron capture mass spectrometry.

  Chemical research in toxicology 20050101

• DNA display II. Genetic manipulation of combinatorial chemistry libraries for small-molecule evolution.

  PLoS biology 20040701

• A mild and efficient protocol for the conversion of carboxylic acids to olefins by a catalytic decarbonylative elimination reaction.

  Chemical communications (Cambridge, England) 20040321

• Pivalate-generating prodrugs and carnitine homeostasis in man.

  Pharmacological reviews 20021201

• New Pd-catalyzed selective reduction of carboxylic acids to aldehydes.

  Chemical communications (Cambridge, England) 20020421

• Highly powerful and practical acylation of alcohols with acid anhydride catalyzed by Bi(OTf)(3).

  The Journal of organic chemistry 20011228

• Observation and elimination of N-acetylation of oligonucleotides prepared using fast-deprotecting phosphoramidites and ultra-mild deprotection.

  Bioorganic & medicinal chemistry letters 20010507