154-93-8 | 1,3-Bis(2-chloroethyl)nitrosourea

Packsize	Purity	Availability	Price	Discounted Price
10mg	95%	in stock	$57.00	$40.00
25mg	95%	in stock	$98.00	$69.00
50mg	95%	in stock	$141.00	$99.00
100mg	95%	in stock	$180.00	$126.00

Description

• Catalog Number: AB57241
• Chemical Name: 1,3-Bis(2-chloroethyl)nitrosourea
• CAS Number: 154-93-8
• Molecular Formula: C5H9Cl2N3O2
• Molecular Weight: 214.0499
• MDL Number: MFCD00057706
• SMILES: ClCCNC(=O)N(CCCl)N=O

Computed Properties

• Complexity: 156
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 4
• XLogP3: 1.5

Literature

• Repairing of N-mustard derivative BO-1055 induced DNA damage requires NER, HR, and MGMT-dependent DNA repair mechanisms.

  Oncotarget 20150922

• Disulfiram is a direct and potent inhibitor of human O6-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells and mouse brain and markedly increases the alkylating DNA damage.

  Carcinogenesis 20140301

• A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans.

  Toxicological sciences : an official journal of the Society of Toxicology 20140101

• Systems level analysis and identification of pathways and networks associated with liver fibrosis.

  PloS one 20140101

• Human three prime exonuclease TREX1 is induced by genotoxic stress and involved in protection of glioma and melanoma cells to anticancer drugs.

  Biochimica et biophysica acta 20130801

• Induction of β-glucuronidase release by cytostatic agents in small tumors.

  Molecular pharmaceutics 20121105

• Impact of the per-operatory application of GLIADEL wafers (BCNU, carmustine) in combination with temozolomide and radiotherapy in patients with glioblastoma multiforme: efficacy and toxicity.

  Clinical neurology and neurosurgery 20121101

• Thioredoxin reductase is inhibited by the carbamoylating activity of the anticancer sulfonylhydrazine drug laromustine.

  Molecular and cellular biochemistry 20121101

• Transfection of a human glioblastoma cell line with liver-type glutaminase (LGA) down-regulates the expression of DNA-repair gene MGMT and sensitizes the cells to alkylating agents.

  Journal of neurochemistry 20121101

• Multiparameter flow cytometry evaluation of plasma cell DNA content and proliferation in 595 transplant-eligible patients with myeloma included in the Spanish GEM2000 and GEM2005<65y trials.

  The American journal of pathology 20121101

• F2A sequence linking MGMT(P140K) and MDR1 in a bicistronic lentiviral vector enables efficient chemoprotection of haematopoietic stem cells.

  Cancer gene therapy 20121101

• Iodine-131 rituximab radioimmunotherapy with BEAM conditioning and autologous stem cell transplant salvage therapy for relapsed/refractory aggressive non-Hodgkin lymphoma.

  Cancer biotherapy & radiopharmaceuticals 20121101

• Carmustine infusion reactions are more common with rapid administration.

  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20121001

• Permeability of gloves to selected chemotherapeutic agents after treatment with alcohol or isopropyl alcohol.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20121001

• O(6) -methylguanine-DNA methyltransferase (MGMT) promoter methylation and low MGMT-encoded protein expression as prognostic markers in glioblastoma patients treated with biodegradable carmustine wafer implants after initial surgery followed by radiotherapy with concomitant and adjuvant temozolomide.

  Cancer 20120915

• Radiation-free allogeneic conditioning with fludarabine, carmustine, and thiotepa for acute lymphoblastic leukemia and other hematologic malignancies necessitating enhanced central nervous system activity.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120901

• Procarbazine, carmustine, and vincristine (PBV) for chemotherapy pre-treated patients with recurrent glioblastoma: a single-institution analysis.

  Journal of neuro-oncology 20120901

• [Do not be deceived: altered magnetic resonance characteristics of gliadel implants after glioma resection].

  Der Radiologe 20120901

• In vivo selection of autologous MGMT gene-modified cells following reduced-intensity conditioning with BCNU and temozolomide in the dog model.

  Cancer gene therapy 20120801

• Nordic MCL2 trial update: six-year follow-up after intensive immunochemotherapy for untreated mantle cell lymphoma followed by BEAM or BEAC + autologous stem-cell support: still very long survival but late relapses do occur.

  British journal of haematology 20120801

• Safety and efficacy of Gliadel wafers for newly diagnosed and recurrent glioblastoma.

  Acta neurochirurgica 20120801

• Safety and efficacy of Gliadel wafers for newly diagnosed and recurrent glioblastomas.

  Acta neurochirurgica 20120801

• Role for cytotoxic chemotherapy in patients with recurrent glioblastoma progressing on bevacizumab: a retrospective case series.

  Expert review of neurotherapeutics 20120801

• Results of phase I study of a multi-modality treatment for newly diagnosed glioblastoma multiforme using local implantation of concurrent BCNU wafers and permanent I-125 seeds followed by fractionated radiation and temozolomide chemotherapy.

  Journal of neuro-oncology 20120701

• Risk factors for development of pneumonitis after high-dose chemotherapy with cyclophosphamide, BCNU and etoposide followed by autologous stem cell transplant.

  Leukemia & lymphoma 20120601

• Inhibitory effect of Pulsatilla chinensis polysaccharides on glioma.

  International journal of biological macromolecules 20120601

• Mini-BEAM is effective as a bridge to transplantation in patients with refractory or relapsed Hodgkin lymphoma who have failed to respond to previous lines of salvage chemotherapy but not in patients with salvage-refractory DLBCL.

  British journal of haematology 20120601

• NICE guidance on the use of carmustine wafers in high grade gliomas: a national study on variation in practice.

  British journal of neurosurgery 20120601

• Second-line salvage chemotherapy for transplant-eligible patients with Hodgkin's lymphoma resistant to platinum-containing first-line salvage chemotherapy.

  Haematologica 20120501

• Characterization of hydrophobic anti-cancer drug-loaded amphiphilic peptides as a gene carrier.

  Journal of cellular biochemistry 20120501

• Improving survival in patients with transformed B cell non Hodgkin lymphoma: consolidation with ⁹⁰Yttrium ibritumomab tiuxetan-BEAM and autologous stem cell transplantation.

  British journal of haematology 20120501

• Recent advances in the molecular understanding of glioblastoma.

  Journal of neuro-oncology 20120501

• MYC+ diffuse large B-cell lymphoma is not salvaged by classical R-ICE or R-DHAP followed by BEAM plus autologous stem cell transplantation.

  Blood 20120501

• Concurrent treatment with BCNU and Gamma Knife radiosurgery in the rat malignant glioma model.

  Journal of neurological surgery. Part A, Central European neurosurgery 20120501

• Tandem chemo-mobilization followed by high-dose melphalan and carmustine with single autologous hematopoietic cell transplantation for multiple myeloma.

  Bone marrow transplantation 20120401

• In vivo magnetic resonance imaging of sodium and diffusion in rat glioma at 21.1 T.

  Magnetic resonance in medicine 20120401

• Temporal changes in magnetic resonance imaging characteristics of Gliadel wafers and of the adjacent brain parenchyma.

  Neuro-oncology 20120401

• Autologous noncryopreserved hematopoietic stem cell transplant with CEAM as a modified conditioning regimen in patients with Hodgkin lymphoma: a single-center experience with a new protocol.

  Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20120401

• The role of BCNU polymer wafers (Gliadel) in the treatment of malignant glioma.

  Neurosurgery clinics of North America 20120401

• Oxaphosphinanes: new therapeutic perspectives for glioblastoma.

  Journal of medicinal chemistry 20120308

• Extended retreatment with brentuximab vedotin (SGN-35) maintains complete remission in patient with recurrent systemic anaplastic large-cell lymphoma.

  Leukemia & lymphoma 20120301

• Biodistribution, radiation dosimetry and scouting of 90Y-ibritumomab tiuxetan therapy in patients with relapsed B-cell non-Hodgkin's lymphoma using 89Zr-ibritumomab tiuxetan and PET.

  European journal of nuclear medicine and molecular imaging 20120301

• Nimustine hydrochloride: the first crystal structure determination of a 2-chloroethyl-N-nitrosourea hydrochloride derivative by X-ray powder diffraction and solid-state NMR.

  Acta crystallographica. Section C, Crystal structure communications 20120301

• Anticancer agents for treatment of tumors in the central nervous system by correspondent substituent substitution and elucidation by pattern recognition methods.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20120301

• Treatment strategies for Hodgkin lymphoma recurring following autologous hematopoietic stem cell transplantation.

  The Korean journal of hematology 20120301

• Retrospective comparison of chemoradiotherapy followed by adjuvant chemotherapy, with or without prior gliadel implantation (carmustine) after initial surgery in patients with newly diagnosed high-grade gliomas.

  International journal of radiation oncology, biology, physics 20120201

• Prognostic factors and survival in a prospective cohort of patients with high-grade glioma treated with carmustine wafers or temozolomide on an intention-to-treat basis.

  Acta neurochirurgica 20120201

• N-nitroso-tris-chloroethylurea induces premalignant squamous dysplasia in mice.

  Cancer prevention research (Philadelphia, Pa.) 20120201

• Comment on Bock et al. Occlusion of surgical opening of the ventricular system with fibrinogen-coated collagen fleece: a case collection study. Acta Neurochir (2011) 153:533-539.

  Acta neurochirurgica 20120201

• [Retrospective analysis of 24 recurrent glioblastoma after chemoradiation and treated with nitrosoureas or irinotecan and bevacizumab].

  Bulletin du cancer 20120201

• Noninvasive diffuse optical monitoring of head and neck tumor blood flow and oxygenation during radiation delivery.

  Biomedical optics express 20120201

• Tandem high-dose chemotherapy and autologous stem cell transplantation in young children with atypical teratoid/rhabdoid tumor of the central nervous system.

  Journal of Korean medical science 20120201

• Incorporation of diffusion-weighted magnetic resonance imaging data into a simple mathematical model of tumor growth.

  Physics in medicine and biology 20120107

• A rapid survival assay to measure drug-induced cytotoxicity and cell cycle effects.

  DNA repair 20120102

• Co-delivery of adenovirus and carmustine by anionic liposomes with synergistic anti-tumor effects.

  Pharmaceutical research 20120101

• Antiangiogenic therapy for patients with recurrent and newly diagnosed malignant gliomas.

  Journal of oncology 20120101

• Inhibition of C6 glioma in vivo by combination chemotherapy of implantation of polymer wafer and intracarotid perfusion of transferrin-decorated nanoparticles.

  Oncology reports 20120101

• Concurrent blood-brain barrier opening and local drug delivery using drug-carrying microbubbles and focused ultrasound for brain glioma treatment.

  Biomaterials 20120101

• [Observational retrospective study to evaluate the effectiveness and safety of treatment schemes with bortezomib for multiple myeloma in our hospital].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20120101

• Volumetric and MGMT parameters in glioblastoma patients: survival analysis.

  BMC cancer 20120101

• [Syringotropic cutaneous T-cell lymphoma mimicking dermatomycosis].

  Annales de dermatologie et de venereologie 20120101

• Glutathione and Bcl-2 targeting facilitates elimination by chemoradiotherapy of human A375 melanoma xenografts overexpressing bcl-xl, bcl-2, and mcl-1.

  Journal of translational medicine 20120101

• Removal of uracil by uracil DNA glycosylase limits pemetrexed cytotoxicity: overriding the limit with methoxyamine to inhibit base excision repair.

  Cell death & disease 20120101

• Prediction of glioblastoma multiform response to bevacizumab treatment using multi-parametric MRI.

  PloS one 20120101

• Inhibition of STAT3 signaling and induction of SHP1 mediate antiangiogenic and antitumor activities of ergosterol peroxide in U266 multiple myeloma cells.

  BMC cancer 20120101

• The role of autologous stem cell transplantation in the treatment of diffuse large B-cell lymphoma.

  Advances in hematology 20120101

• Serial measurements of cardiac biomarkers in patients after allogeneic hematopoietic stem cell transplantation.

  Journal of experimental & clinical cancer research : CR 20120101

• MGMT promoter methylation in gliomas-assessment by pyrosequencing and quantitative methylation-specific PCR.

  Journal of translational medicine 20120101

• Iodine-125 brachytherapy for brain tumours--a review.

  Radiation oncology (London, England) 20120101

• AIDS-Related Non-Hodgkin's Lymphoma in the Era of Highly Active Antiretroviral Therapy.

  Advances in hematology 20120101

• Toxin-based targeted therapy for malignant brain tumors.

  Clinical & developmental immunology 20120101

• Low levels of Human Cytomegalovirus Infection in Glioblastoma multiforme associates with patient survival; -a case-control study.

  Herpesviridae 20120101

• [Lenalidomide induced therapeutic response in a patient with aggressive multi-system Langerhans cell histiocytosis resistant to 2-chloro-deoxyadenosine and early relapsing after high-dose BEAM chemotherapy with autologous peripheral blood stem cell transplantation].

  Vnitrni lekarstvi 20120101

• Cellular-based immunotherapies for patients with glioblastoma multiforme.

  Clinical & developmental immunology 20120101

• Inhibition of HSP27 alone or in combination with pAKT inhibition as therapeutic approaches to target SPARC-induced glioma cell survival.

  Molecular cancer 20120101

• Glutathione homeostasis and functions: potential targets for medical interventions.

  Journal of amino acids 20120101

• Subgroup economic analysis for glioblastoma in a health resource-limited setting.

  PloS one 20120101

• High-Dose Therapy and Autologous Hematopoietic Progenitor Cells Transplantation for Recurrent or Refractory Hodgkin's Lymphoma: Analysis of King Hussein Cancer Center Results and Prognostic Variables.

  ISRN oncology 20120101

• Novel therapies in glioblastoma.

  Neurology research international 20120101

• Current trends in targeted therapies for glioblastoma multiforme.

  Neurology research international 20120101

• Long-term survival after gamma knife radiosurgery in a case of recurrent glioblastoma multiforme: a case report and review of the literature.

  Case reports in medicine 20120101

• Vorinostat approved in Japan for treatment of cutaneous T-cell lymphomas: status and prospects.

  OncoTargets and therapy 20120101

• Improving thermal stability and efficacy of BCNU in treating glioma cells using PAA-functionalized graphene oxide.

  International journal of nanomedicine 20120101

• Nanoengineered drug-releasing Ti wires as an alternative for local delivery of chemotherapeutics in the brain.

  International journal of nanomedicine 20120101

• Induction of selective blood-tumor barrier permeability and macromolecular transport by a biostable kinin B1 receptor agonist in a glioma rat model.

  PloS one 20120101

• Immunotherapy targets in pediatric cancer.

  Frontiers in oncology 20120101

• Current and emerging pharmacotherapies for primary CNS lymphoma.

  Clinical Medicine Insights. Oncology 20120101

• Combination of RGD compound and low-dose paclitaxel induces apoptosis in human glioblastoma cells.

  PloS one 20120101

• Therapeutic strategies based on polymeric microparticles.

  Journal of biomedicine & biotechnology 20120101

• Schisandrin B as a hormetic agent for preventing age-related neurodegenerative diseases.

  Oxidative medicine and cellular longevity 20120101

• Protection by Salvia extracts against oxidative and alkylation damage to DNA in human HCT15 and CO115 cells.

  Journal of toxicology and environmental health. Part A 20120101

• Hydroxyapatite nanoparticles inhibit the growth of human glioma cells in vitro and in vivo.

  International journal of nanomedicine 20120101

• Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies.

  PloS one 20120101

• Polifeprosan 20, 3.85% carmustine slow-release wafer in malignant glioma: evidence for role in era of standard adjuvant temozolomide.

  Core evidence 20120101

• Combination of arsenic trioxide and BCNU synergistically triggers redox-mediated autophagic cell death in human solid tumors.

  Free radical biology & medicine 20111215

• Treosulfan-based preparative regimens for allo-HSCT in childhood hematological malignancies: a retrospective study on behalf of the EBMT pediatric diseases working party.

  Bone marrow transplantation 20111201

• The risk factors for oral mucositis and the effect of cryotherapy in patients after the BEAM and HD-l-PAM 200 mg/m(2) autologous hematopoietic stem cell transplantation.

  European journal of oncology nursing : the official journal of European Oncology Nursing Society 20111201

• A new semiparametric estimation method for accelerated hazard model.

  Biometrics 20111201

• O(6)-Methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: enzyme activity, promoter methylation and immunohistochemistry.

  Biochimica et biophysica acta 20111201

• Efficacy and safety of the third-generation chloroethylnitrosourea fotemustine for the treatment of chemorefractory T-cell lymphomas.

  European journal of haematology 20111201

• Knockdown of the potential cancer stem-like cell marker Rex-1 improves chemotherapeutic effects in gliomas.

  Human gene therapy 20111201

• Acquired STAT4 deficiency as a consequence of cancer chemotherapy.

  Blood 20111201

• Retrospective comparison of chemoradiotherapy followed by adjuvant chemotherapy, with or without previous gliadel implantation (carmustine) after initial surgery in patients with newly diagnosed high-grade gliomas: in regard to Noel et al. (Int J Radiat Oncol Biol Phys 2011; DOI: 10.1016/j.ijrobp.2010.11.073).

  International journal of radiation oncology, biology, physics 20111201

• Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

  PLoS computational biology 20111201

• Adenovirus as a new agent for multiple myeloma therapies: Opportunities and restrictions.

  The Korean journal of hematology 20111201

• Magnetic resonance imaging appearance and changes on intracavitary Gliadel wafer placement: A pilot study.

  World journal of radiology 20111128

• 4-nitrobenzyloxycarbonyl derivatives of O(6)-benzylguanine as hypoxia-activated prodrug inhibitors of O(6)-alkylguanine-DNA alkyltransferase (AGT), which produces resistance to agents targeting the O-6 position of DNA guanine.

  Journal of medicinal chemistry 20111110

• Validation and simplification of the Radiation Therapy Oncology Group recursive partitioning analysis classification for glioblastoma.

  International journal of radiation oncology, biology, physics 20111101

• Tandem high-dose therapy in relapsed and refractory B-cell lymphoma: results of a prospective phase II trial of myeloablative chemotherapy, followed by escalated radioimmunotherapy with (131)I-anti-CD20 antibody and stem cell rescue.

  Annals of hematology 20111101

• Postoperative seizure in high grade glioma patients treated with BCNU wafers. A mono-institutional experience.

  Journal of neuro-oncology 20111101

• Complete response induced by fotemustine given as single agent in a patient with primary central nervous system non-Hodgkin aggressive lymphoma relapsed after high-dose chemotherapy and autologous stem cell support.

  Leukemia & lymphoma 20111101

• Surgery of malignant gliomas: advances and perspectives.

  Current opinion in oncology 20111101

• Loco-regional treatments in first-diagnosis glioblastoma: literature review on association between Stupp protocol and Gliadel.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20111101

• Lecture: fotemustine in brain tumors.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20111101

• Narrowband ultraviolet B phototherapy of early stage mycosis fungoides in korean patients.

  Annals of dermatology 20111101

• Current approaches to the treatment of non-Hodgkin's lymphoma.

  Hematology reports 20111028

• Malignant melanoma of the nasal cavity: a case report with examination of KIT and platelet derived growth factor receptor-α(PDGFRA).

  Rare tumors 20111021

• CHOD/BVAM chemotherapy and whole-brain radiotherapy for newly diagnosed primary central nervous system lymphoma.

  International journal of radiation oncology, biology, physics 20111001

• A comprehensive outlook on intracerebral therapy of malignant gliomas.

  Critical reviews in oncology/hematology 20111001

• High-dose therapy and autologous hematopoietic cell transplantation in peripheral T cell lymphoma (PTCL): analysis of prognostic factors.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20111001

• miR-200c is upregulated by oxidative stress and induces endothelial cell apoptosis and senescence via ZEB1 inhibition.

  Cell death and differentiation 20111001

• Carmustine induces ERK- and JNK-dependent cell death of neuronally-differentiated PC12 cells via generation of reactive oxygen species.

  Toxicology in vitro : an international journal published in association with BIBRA 20111001

• Gliadel wafers acting as a lattice for bacterial growth: a case illustration.

  Acta neurochirurgica 20111001

• Intellectual impairment after treatment for medulloblastoma and astrocytoma in childhood: the Brazilian experience.

  Journal of pediatric hematology/oncology 20111001

• A triple-drug combination to prevent nausea and vomiting following BEAM chemotherapy before autologous hematopoietic stem cell transplantation.

  Transplantation proceedings 20111001

• Efficiency of supersaturated calcium phosphate mouth rinse treatment in patients receiving high-dose melphalan or BEAM prior to autologous blood stem cell transplantation: a single-center experience.

  Transplantation proceedings 20111001

• Correlation of MGMT promoter methylation status with gene and protein expression levels in glioblastoma.

  Clinics (Sao Paulo, Brazil) 20111001

• Systemic use of tumor necrosis factor alpha as an anticancer agent.

  Oncotarget 20111001

• In vivo detection of cortical abnormalities in BCNU-treated rats, model of cortical dysplasia, using manganese-enhanced magnetic resonance imaging.

  Neuroscience 20110929

• Favorable prognosis in patients with high-grade glioma with radiation necrosis: the University of Colorado reoperation series.

  International journal of radiation oncology, biology, physics 20110901

• Sagopilone (ZK-EPO, ZK 219477) for recurrent glioblastoma. A phase II multicenter trial by the European Organisation for Research and Treatment of Cancer (EORTC) Brain Tumor Group.

  Annals of oncology : official journal of the European Society for Medical Oncology 20110901

• Impact of therapy on quality of life, neurocognitive function and their correlates in glioblastoma multiforme: a review.

  Journal of neuro-oncology 20110901

• d-Amphetamine-induced cytotoxicity and oxidative stress in isolated rat hepatocytes.

  Pathophysiology : the official journal of the International Society for Pathophysiology 20110901

• The chemopreventive effect of dimethylthiourea against carmustine-induced myelotoxicity in rats.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110901

• Self-protecting core-shell magnetic nanoparticles for targeted, traceable, long half-life delivery of BCNU to gliomas.

  Biomaterials 20110901

• Phase I study of tandem high-dose chemotherapy with autologous peripheral blood stem cell rescue for children with recurrent brain tumors: a Pediatric Blood and MarrowTransplant Consortium study.

  Pediatric blood & cancer 20110901

• The efficacy of carmustine wafers for older patients with glioblastoma multiforme: prolonging survival.

  Neurological research 20110901

• [Pulmonary Langerhans histiocytosis and Hodgkin's lymphoma].

  Revue des maladies respiratoires 20110901

• Silencing of MGMT with small interference RNA reversed resistance in human BCUN-resistant glioma cell lines.

  Chinese medical journal 20110901

• The rate of interleukin-1beta secretion in different myeloid cells varies with the extent of redox response to Toll-like receptor triggering.

  The Journal of biological chemistry 20110805

• Association of HSV reactivation and pro-inflammatory cytokine levels with the severity of stomatitis after BEAM chemotherapy and autologous SCT.

  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20110801

• Increasing age at diagnosis and worsening renal function in patients with primary central nervous system lymphoma.

  Journal of neuro-oncology 20110801

• Radiotherapy and temozolomide for newly diagnosed glioblastoma and anaplastic astrocytoma: validation of Radiation Therapy Oncology Group-Recursive Partitioning Analysis in the IMRT and temozolomide era.

  Journal of neuro-oncology 20110801

• The sequential use of carmustine wafers (Gliadel®) and post-operative radiotherapy with concomitant temozolomide followed by adjuvant temozolomide: a clinical review.

  British journal of neurosurgery 20110801

• Autologous versus reduced-intensity allogeneic hematopoietic cell transplantation for patients with chemosensitive follicular non-Hodgkin lymphoma beyond first complete response or first partial response.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110701

• A Phase I trial: dose escalation of melphalan in the 'BEAM' regimen using amifostine cytoprotection.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110701

• Selective accumulation of hybrid liposomes into adult T-cell leukemia cells along with induction of apoptosis.

  Bioorganic & medicinal chemistry letters 20110701

• Implementation of neuro-oncology service reconfiguration in accordance with NICE guidance provides enhanced clinical care for patients with glioblastoma multiforme.

  British journal of cancer 20110607

• Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent glioblastoma multiforme.

  Journal of neuro-oncology 20110601

• Long-term follow-up of tandem high-dose therapy with autologous stem cell support for adults with high-risk age-adjusted international prognostic index aggressive non-Hodgkin Lymphomas: a GOELAMS pilot study.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110601

• Clinical significance of positive cranial bone flap cultures and associated risk of surgical site infection after craniotomies or craniectomies.

  Journal of neurosurgery 20110601

• Candida infection of the central nervous system following neurosurgery: a 12-year review.

  Acta neurochirurgica 20110601

• Cytoreductive surgery of glioblastoma as the key to successful adjuvant therapies: new arguments in an old discussion.

  Acta neurochirurgica 20110601

• Mathematical modeling to distinguish cell cycle arrest and cell killing in chemotherapeutic concentration response curves.

  Journal of pharmacokinetics and pharmacodynamics 20110601

• Carmustine-impregnated wafers and their impact in the management of high-grade glioma.

  Expert opinion on pharmacotherapy 20110601

• Assessment of multiparametric MRI in a human glioma model to monitor cytotoxic and anti-angiogenic drug effects.

  NMR in biomedicine 20110601

• Primary adenosquamous carcinoma of the colon.

  Journal of the Korean Surgical Society 20110601

• 5-oxo-ETE is a major oxidative stress-induced arachidonate metabolite in B lymphocytes.

  Free radical biology & medicine 20110515

• A new schedule of fotemustine in temozolomide-pretreated patients with relapsing glioblastoma.

  Journal of neuro-oncology 20110501

• Wilms' tumor 1 silencing decreases the viability and chemoresistance of glioblastoma cells in vitro: a potential role for IGF-1R de-repression.

  Journal of neuro-oncology 20110501

• Hematopoietic stem cell mobilization with the reversible CXCR4 receptor inhibitor plerixafor (AMD3100)-Polish compassionate use experience.

  Annals of hematology 20110501

• Pro-apoptotic role of integrin β3 in glioma cells.

  Journal of neurochemistry 20110501

• Early toxicity predicts long-term survival in high-grade glioma.

  British journal of cancer 20110426

• Candida parapsilosis meningitis associated with Gliadel (BCNU) wafer implants.

  British journal of neurosurgery 20110401

• Earlier detection of tumor treatment response using magnetic resonance diffusion imaging with oscillating gradients.

  Magnetic resonance imaging 20110401

• Intracranial microcapsule drug delivery device for the treatment of an experimental gliosarcoma model.

  Biomaterials 20110401

• Environmental mutagens may be implicated in the emergence of drug-resistant microorganisms.

  FEMS microbiology letters 20110401

• Inhibition of human brain malignant glioblastoma cells using carmustine-loaded catanionic solid lipid nanoparticles with surface anti-epithelial growth factor receptor.

  Biomaterials 20110401

• Intracellular trafficking considerations in the development of natural ligand-drug molecular conjugates for cancer.

  Annals of biomedical engineering 20110401

• (90)Y ibritumomab tiuxetan (Zevalin) combined with BEAM (Z -BEAM) conditioning regimen plus autologous stem cell transplantation in relapsed or refractory low-grade CD20-positive B-cell lymphoma. A GELA phase II prospective study.

  Clinical lymphoma, myeloma & leukemia 20110401

• The use of convection-enhanced delivery with liposomal toxins in neurooncology.

  Toxins 20110401

• Chemotherapy wafers for high grade glioma.

  The Cochrane database of systematic reviews 20110316

• Heavy chain ferritin siRNA delivered by cationic liposomes increases sensitivity of cancer cells to chemotherapeutic agents.

  Cancer research 20110315

• Adenovirus-mediated transfer of siRNA against basic fibroblast growth factor mRNA enhances the sensitivity of glioblastoma cells to chemotherapy.

  Medical oncology (Northwood, London, England) 20110301

• Clinical emergence of neurometastatic merkel cell carcinoma: a surgical case series and literature review.

  Journal of neuro-oncology 20110301

• Clinical outcome of autologous peripheral blood stem cell transplantation in opticospinal and conventional forms of secondary progressive multiple sclerosis in a Chinese population.

  Annals of hematology 20110301

• Surgical outcomes for older patients with glioblastoma multiforme: preoperative factors associated with decreased survival. Clinical article.

  Journal of neurosurgery 20110301

• Imaging in real-time with FRET the redox response of tumorigenic cells to glutathione perturbations in a microscale flow.

  Integrative biology : quantitative biosciences from nano to macro 20110301

• Occlusion of surgical opening of the ventricular system with fibrinogen-coated collagen fleece: a case collection study.

  Acta neurochirurgica 20110301

• Space-occupying cyst development in the resection cavity of malignant gliomas following Gliadel® implantation--incidence, therapeutic strategies, and outcome.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20110301

• Controversies in the adjuvant therapy of high-grade gliomas.

  The oncologist 20110301

• The effect of cytostatics and hyperthermia on RAJI human lymphoma cells.

  Experimental oncology 20110301

• Safety and feasibility of the adjunct of local chemotherapy with biodegradable carmustine (BCNU) wafers to the standard multimodal approach to high grade gliomas at first diagnosis.

  Journal of neurosurgical sciences 20110301

• Depressogenic effects of medications: a review.

  Dialogues in clinical neuroscience 20110301

• Development of cortical malformations in BCNU-treated rat, model of cortical dysplasia.

  Neuroscience 20110223

• Autologous peripheral blood stem cell transplantation in children with refractory or relapsed lymphoma: results of Children's Oncology Group study A5962.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110201

• BEAM or BuCyE high-dose chemotherapy followed by autologous stem cell transplantation in non-Hodgkin's lymphoma patients: a single center comparative analysis of efficacy and toxicity.

  Leukemia research 20110201

• Effect of protein S-glutathionylation on Ca2+ homeostasis in cultured aortic endothelial cells.

  American journal of physiology. Heart and circulatory physiology 20110201

• Effect of imaging and catheter characteristics on clinical outcome for patients in the PRECISE study.

  Journal of neuro-oncology 20110101

• The effectiveness of a magnetic nanoparticle-based delivery system for BCNU in the treatment of gliomas.

  Biomaterials 20110101

• Systematic review of medical treatment in melanoma: current status and future prospects.

  The oncologist 20110101

• Antiangiogenic agents in the treatment of recurrent or newly diagnosed glioblastoma: analysis of single-agent and combined modality approaches.

  Radiation oncology (London, England) 20110101

• Exploiting the complexity of the genome and transcriptome using pharmacogenomics towards personalized medicine.

  Genome biology 20110101

• Enhancement of radiosensitivity in human glioblastoma cells by the DNA N-mustard alkylating agent BO-1051 through augmented and sustained DNA damage response.

  Radiation oncology (London, England) 20110101

• O6-Methylguanine-DNA methyltransferase protein expression by immunohistochemistry in brain and non-brain systemic tumours: systematic review and meta-analysis of correlation with methylation-specific polymerase chain reaction.

  BMC cancer 20110101

• Pathogenesis, diagnosis and management of primary melanoma of the colon.

  World journal of surgical oncology 20110101

• (-)Schisandrin B ameliorates paraquat-induced oxidative stress by suppressing glutathione depletion and enhancing glutathione recovery in differentiated PC12 cells.

  BioFactors (Oxford, England) 20110101

• Brain tumor and Gliadel wafer treatment.

  Indian journal of cancer 20110101

• Drug transport in brain via the cerebrospinal fluid.

  Fluids and barriers of the CNS 20110101

• EGFR and EGFRvIII undergo stress- and EGFR kinase inhibitor-induced mitochondrial translocalization: a potential mechanism of EGFR-driven antagonism of apoptosis.

  Molecular cancer 20110101

• Serum after autologous transplantation stimulates proliferation and expansion of human hematopoietic progenitor cells.

  PloS one 20110101

• Romidepsin: evidence for its potential use to manage previously treated cutaneous T cell lymphoma.

  Core evidence 20110101

• Achievement of three year remission with bevacizumab and irinotecan in recurrent glioblastoma multiforme: a case report.

  Clinical Medicine Insights. Oncology 20110101

• Improved survival following surgery and radiation therapy for olfactory neuroblastoma: analysis of the SEER database.

  Radiation oncology (London, England) 20110101

• Lights and shadows of cyclophosphamide in the treatment of multiple sclerosis.

  Autoimmune diseases 20110101

• Transcriptome sequencing and microarray development for the Manila clam, Ruditapes philippinarum: genomic tools for environmental monitoring.

  BMC genomics 20110101

• Extrinsic apoptotic pathways: a new potential 'target' for more sufficient therapy in a case of cutaneous anaplastic large cd30+ alk-T-cell lymphoma.

  Indian journal of dermatology 20110101

• FANCD1/BRCA2 plays predominant role in the repair of DNA damage induced by ACNU or TMZ.

  PloS one 20110101

• In silico studies on marine actinomycetes as potential inhibitors for Glioblastoma multiforme.

  Bioinformation 20110101

• Bevacizumab for the treatment of recurrent glioblastoma.

  Clinical Medicine Insights. Oncology 20110101

• Management of provoked seizure.

  Annals of Indian Academy of Neurology 20110101

• Battling Chemotherapy-induced Nausea and Vomiting in Cancer Palliative Care.

  Indian journal of palliative care 20110101

• Primary malignant melanoma of the uterine cervix treated with ultraradical surgery: a case report.

  ISRN obstetrics and gynecology 20110101

• Epigenetic changes in cancer.

  F1000 biology reports 20110101

• The Management of Classical Hodgkin's Lymphoma: Past, Present, and Future.

  Advances in hematology 20110101

• Platelet factor-4 and its p17-70 peptide inhibit myeloma proliferation and angiogenesis in vivo.

  BMC cancer 20110101

• Bendamustine: safety and efficacy in the management of indolent non-hodgkins lymphoma.

  Clinical Medicine Insights. Oncology 20110101

• Multiple myeloma with lung plasmacytoma.

  Lung India : official organ of Indian Chest Society 20110101

• Treatment of HIV-related primary central nervous system lymphoma with AZT high dose, HAART, interleukin-2 and foscarnet in three patients.

  European journal of medical research 20110101

• Current review of in vivo GBM rodent models: emphasis on the CNS-1 tumour model.

  ASN neuro 20110101

• Paclitaxel delivery to brain tumors from hydrogels: a computational study.

  Biotechnology progress 20110101

• Carmustine wafer implantation when surgical cavity is communicating with cerebral ventricles: technical considerations on a clinical series.

  World neurosurgery 20110101

• [Regional chemoinfusion and radiation therapy to patients with breast cancer metastases to the brain: preliminary results].

  Vestnik khirurgii imeni I. I. Grekova 20110101

• Nitrosourea chemotherapeutic agents: Bis(chloroethyl) nitrosourea.

  Report on carcinogens : carcinogen profiles 20110101

• Poly(ADP-ribose) polymerase inhibition: a new direction for BRCA and triple-negative breast cancer?

  Breast cancer research : BCR 20110101

• Remarkable inhibitory effects of hybrid liposomes on growth of human colon cancer cells through induction of cell cycle arrest along with apoptosis.

  International journal of nanomedicine 20110101

• Chemoresistance of glioblastoma cancer stem cells--much more complex than expected.

  Molecular cancer 20110101

• Systemic remodeling of the redox regulatory network due to RNAi perturbations of glutaredoxin 1, thioredoxin 1, and glucose-6-phosphate dehydrogenase.

  BMC systems biology 20110101

• Long survival of primary diffuse leptomeningeal gliomatosis following radiotherapy and temozolomide: case report and literature review.

  European journal of medical research 20110101

• Schisandrin B enhances the glutathione redox cycling and protects against oxidant injury in different types of cultured cells.

  BioFactors (Oxford, England) 20110101

• Biochemotherapy with carmustine, cisplatin, dacarbazine, tamoxifen and low-dose interleukin-2 for patients with metastatic malignant melanoma.

  Chang Gung medical journal 20110101

• Differential Secondary Reconstitution of In Vivo-Selected Human SCID-Repopulating Cells in NOD/SCID versus NOD/SCID/γ chain Mice.

  Bone marrow research 20110101

• Novel formulation of a methotrexate derivative with a lipid nanoemulsion.

  International journal of nanomedicine 20110101

• Reduction of atherosclerotic lesions in rabbits treated with etoposide associated with cholesterol-rich nanoemulsions.

  International journal of nanomedicine 20110101

• Cerebral melanoma metastases: a critical review on diagnostic methods and therapeutic options.

  ISRN surgery 20110101

• Innovative Therapies against Human Glioblastoma Multiforme.

  ISRN oncology 20110101

• Low back pain as the presenting sign in a patient with primary extradural melanoma of the thoracic spine--a metastatic disease 17 years after complete surgical resection.

  World journal of surgical oncology 20110101

• Diffusion MR Imaging of the Brain in Patients with Cancer.

  International journal of molecular imaging 20110101

• The three-layer concentric model of glioblastoma: cancer stem cells, microenvironmental regulation, and therapeutic implications.

  TheScientificWorldJournal 20110101

• Familial glioblastoma: A case report of glioblastoma in two brothers and review of literature.

  Surgical neurology international 20110101

• Clinical Application of Mesenchymal Stem Cells in the Treatment and Prevention of Graft-versus-Host Disease.

  Advances in hematology 20110101

• Challenges in immunotherapy presented by the glioblastoma multiforme microenvironment.

  Clinical & developmental immunology 20110101

• Global analysis of DNA methylation by Methyl-Capture sequencing reveals epigenetic control of cisplatin resistance in ovarian cancer cell.

  PloS one 20110101

• The state of research into children with cancer across Europe: new policies for a new decade.

  Ecancermedicalscience 20110101

• Cisplatin tumor biodistribution and efficacy after intratumoral injection of a biodegradable extended release implant.

  Chemotherapy research and practice 20110101

• Bevacizumab improves quality of life in patients with recurrent glioblastoma.

  Chemotherapy research and practice 20110101

• Multiple myeloma and bisphosphonate-related osteonecrosis of the mandible associated with dental implants.

  Case reports in dentistry 20110101

• Impact of Autophagy on Chemotherapy and Radiotherapy Mediated Tumor Cytotoxicity: 'To Live or not to Live'.

  Frontiers in oncology 20110101

• Combined modality approaches in the management of adult glioblastoma.

  Frontiers in oncology 20110101

• Mathematical and experimental approaches to identify and predict the effects of chemotherapy on neuroglial precursors.

  Cancer research 20101215

• Cancer and renal insufficiency results of the BIRMA study.

  British journal of cancer 20101207

• Melatonin alters age-related changes in transcription factors and kinase activation.

  Neurochemical research 20101201

• Simultaneous bilateral spontaneous pneumothorax following high-dose chemotherapy and bone marrow transplantation for mantle cell lymphoma without evidence of pulmonary disease.

  International journal of clinical oncology 20101201

• Carboplatin and docetaxel-induced acute pancreatitis: brief report.

  International journal of clinical oncology 20101201

• PCR diagnostics and monitoring of adenoviral infections in hematopoietic stem cell transplantation recipients.

  Archives of virology 20101201

• [Local antitumor treatments].

  Neuro-Chirurgie 20101201

• Cerebrospinal fluid leak during treatment with bevacizumab and irinotecan after carmustine-impregnated wafers placement in patients with grade 2 oligodendroglioma and glioblastoma multiforme: report of two cases and review of literature.

  Cancer investigation 20101201

• Dose intensity of chemotherapy in patients with relapsed Hodgkin's lymphoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101201

• Influence of cell cycle checkpoints and p53 function on the toxicity of temozolomide in human pancreatic cancer cells.

  Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20101201

• The DAC system and associations with multiple myeloma.

  Investigational new drugs 20101201

• Pandemic (H1N1) 2009 infection in patients with hematologic malignancy.

  Emerging infectious diseases 20101201

• Inhibitory effects of TNP-470 in combination with BCNU on tumor growth of human glioblastoma xenografts.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20101201

• Risk management in the treatment of malignant gliomas with BCNU wafer implants.

  Central European neurosurgery 20101101

• Investigation of maternal melatonin effect on the hippocampal formation of newborn rat model of intrauterine cortical dysplasia.

  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20101101

• Can high-dose fotemustine reverse MGMT resistance in glioblastoma multiforme?

  Journal of neuro-oncology 20101101

• Quantitative relationship between guanine O(6)-alkyl lesions produced by Onrigin™ and tumor resistance by O(6)-alkylguanine-DNA alkyltransferase.

  Biochemical pharmacology 20101101

• The first 3 months after BCNU wafers implantation in high-grade glioma patients: clinical and radiological considerations on a clinical series.

  Acta neurochirurgica 20101101

• Molecular diagnostics of gliomas: state of the art.

  Acta neuropathologica 20101101

• Assessment of multiexponential diffusion features as MRI cancer therapy response metrics.

  Magnetic resonance in medicine 20101101

• Engineering nanomedicines for improved melanoma therapy: progress and promises.

  Nanomedicine (London, England) 20101101

• [Lymphoma-like course in aggressive adult multisystem Langerhans cell histiocytosis and the benefit of PET/CT imaging in evaluation of diffuse metabolic activity of lung parenchyma].

  Vnitrni lekarstvi 20101101

• Toxin-based therapeutic approaches.

  Toxins 20101101

• Targeted toxins in brain tumor therapy.

  Toxins 20101101

• Clinically relevant doses of chemotherapy agents reversibly block formation of glioblastoma neurospheres.

  Cancer letters 20101028

• Activity of irinotecan and temozolomide in the presence of O6-methylguanine-DNA methyltransferase inhibition in neuroblastoma pre-clinical models.

  British journal of cancer 20101026

• Total body irradiation compared with BEAM: Long-term outcomes of peripheral blood autologous stem cell transplantation for non-Hodgkin's lymphoma.

  International journal of radiation oncology, biology, physics 20101001

• Novel magnetic/ultrasound focusing system enhances nanoparticle drug delivery for glioma treatment.

  Neuro-oncology 20101001

• First-line treatment of malignant glioma with carmustine implants followed by concomitant radiochemotherapy: a multicenter experience.

  Neurosurgical review 20101001

• New results will change the paradigm for phase I trials and drug approval.

  The oncologist 20101001

• Treatment of recurrent glioblastoma with intra-arterial BCNU [1, 3-bis (2-chloroethyl)-1-nitrosourea].

  Arquivos de neuro-psiquiatria 20101001

• Selection of genetically modified hematopoietic cells in vitro and in vivo using alkylating agent lysomustine.

  Analytical biochemistry 20100915

• MGMT gene promoter methylation correlates with tolerance of temozolomide treatment in melanoma but not with clinical outcome.

  British journal of cancer 20100907

• HDMX regulates p53 activity and confers chemoresistance to 3-bis(2-chloroethyl)-1-nitrosourea.

  Neuro-oncology 20100901

• Ultrasound-enhanced drug transport and distribution in the brain.

  AAPS PharmSciTech 20100901

• American Association for Cancer Research Genetics and Biology of Brain Cancers 2009, December 13-15, 2009, San Diego, CA.

  Journal of neuro-oncology 20100901

• Phase II NCCTG trial of RT + irinotecan and adjuvant BCNU plus irinotecan for newly diagnosed GBM.

  Journal of neuro-oncology 20100801

• Phase II trial of intratumoral BCNU injection and radiotherapy on untreated adult malignant glioma.

  Journal of neuro-oncology 20100801

• Immunomagnetic selection of CD34(+) cells carried out in cryopreserved cell concentrates from a paediatric patient affected with non-Hodgkin lymphoma.

  Transfusion medicine (Oxford, England) 20100801

• Phase I/II trial of GN-BVC, a gemcitabine and vinorelbine-containing conditioning regimen for autologous hematopoietic cell transplantation in recurrent and refractory hodgkin lymphoma.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20100801

• Analysis of self-inactivating lentiviral vector integration sites and flanking gene expression in human peripheral blood progenitor cells after alkylator chemotherapy.

  Human gene therapy 20100801

• Phase III randomized trial of CED of IL13-PE38QQR vs Gliadel wafers for recurrent glioblastoma.

  Neuro-oncology 20100801

• Corneal perforation with preseptal cellulitis in a patient with acute lymphocytic leukemia.

  Journal of Korean medical science 20100801

• Monotherapy with methotrexate for primary central nervous lymphoma has single agent activity in the absence of radiotherapy: a single institution cohort.

  Journal of neuro-oncology 20100701

• Carmustine wafers (Gliadel) plus concomitant temozolomide therapy after resection of malignant astrocytoma: growing evidence for safety and efficacy.

  Annals of surgical oncology 20100701

• Biodegradable carmustine wafers (Gliadel) alone or in combination with chemoradiotherapy: the French experience.

  Annals of surgical oncology 20100701

• Overcoming drug resistance in mantle cell lymphoma using a combination of dose-dense and intense therapy.

  Cancer investigation 20100701

• Initial experience involving treatment and retreatment with carmustine wafers in combination with oral temozolomide: long-term survival in a child with relapsed glioblastoma multiforme.

  Journal of pediatric hematology/oncology 20100701

• JAAD grand rounds quiz*: Dusky intertriginous plaques and acral erythema after bone marrow transplant.

  Journal of the American Academy of Dermatology 20100701

• Efficient and stable MGMT-mediated selection of long-term repopulating stem cells in nonhuman primates.

  The Journal of clinical investigation 20100701

• Recurrent high-grade glioma.

  Current treatment options in neurology 20100701

• Photodynamic therapy for multi-resistant cutaneous Langerhans cell histiocytosis.

  Rare tumors 20100630

• Systematic analysis of the antiproliferative effects of novel and standard anticancer agents in rhabdoid tumor cell lines.

  Anti-cancer drugs 20100601

• Protective effect of N-acetylcysteine against carmustine-induced myelotoxicity in rats.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100601

• High-dose immunoablation with autologous haematopoietic stem cell transplantation in aggressive multiple sclerosis: a single centre 10-year experience.

  Multiple sclerosis (Houndmills, Basingstoke, England) 20100601

• Pegfilgrastim appears equivalent to daily dosing of filgrastim to treat neutropenia after autologous peripheral blood stem cell transplantation in patients with non-Hodgkin lymphoma.

  Clinical lymphoma, myeloma & leukemia 20100601

• Vincristine in high-grade glioma.

  Anticancer research 20100601

• In vitro comparison of O4-benzylfolate modulated, BCNU-induced toxicity in human bone marrow using CFU-GM and tumor cell lines.

  Cancer chemotherapy and pharmacology 20100501

• A proposed classification system that projects outcomes based on preoperative variables for adult patients with glioblastoma multiforme.

  Journal of neurosurgery 20100501

• Treatment of atypical central neurocytoma in a child with high dose chemotherapy and autologous stem cell rescue.

  Journal of neuro-oncology 20100501

• Molecular evolution of Theta-class glutathione transferase for enhanced activity with the anticancer drug 1,3-bis-(2-chloroethyl)-1-nitrosourea and other alkylating agents.

  Archives of biochemistry and biophysics 20100501

• Blood-brain barrier disruption with focused ultrasound enhances delivery of chemotherapeutic drugs for glioblastoma treatment.

  Radiology 20100501

• Diagnosis and management of mycosis fungoides.

  Oncology (Williston Park, N.Y.) 20100501

• Impact of high-dose chemotherapy on the ability to deliver subsequent local-regional radiotherapy for breast cancer: analysis of Cancer and Leukemia Group B Protocol 9082.

  International journal of radiation oncology, biology, physics 20100401

• Effect of O6-chloroethylguanine DNA lesions on the kinetics and mechanism of micronucleus induction in vivo.

  Environmental and molecular mutagenesis 20100401

• The prognostic IDH1( R132 ) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma.

  Acta neuropathologica 20100401

• Final analysis of the UKLG LY02 trial comparing 6-8 cycles of CHOP with 3 cycles of CHOP followed by a BEAM autograft in patients <65 years with poor prognosis histologically aggressive NHL.

  British journal of haematology 20100401

• Rituximab retherapy in patients with relapsed aggressive B cell and mantle cell lymphoma.

  Annals of hematology 20100301

• The combination of thalidomide, cyclophosphamide and dexamethasone is potentially useful in highly resistant Hodgkin's lymphoma.

  European journal of haematology 20100301

• Glutathione S-transferase M1 inhibits dexamethasone-induced apoptosis in association with the suppression of Bim through dual mechanisms in a lymphoblastic leukemia cell line.

  Cancer science 20100301

• Evaluation of treatment-associated inflammatory response on diffusion-weighted magnetic resonance imaging and 2-[18F]-fluoro-2-deoxy-D-glucose-positron emission tomography imaging biomarkers.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20100301

• Combination of intracranial temozolomide with intracranial carmustine improves survival when compared with either treatment alone in a rodent glioma model.

  Neurosurgery 20100301

• N,N'-Bis(2-chloroethyl)-N-nitrosourea (BCNU)-induced Apoptosis of Neural Progenitor Cells in the Developing Fetal Rat Brain.

  Journal of toxicologic pathology 20100301

• Extended O6-methylguanine methyltransferase promoter hypermethylation following n-butylidenephthalide combined with 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) on inhibition of human hepatocellular carcinoma cell growth.

  Journal of agricultural and food chemistry 20100210

• Brazilian experience with two conditioning regimens in patients with multiple sclerosis: BEAM/horse ATG and CY/rabbit ATG.

  Bone marrow transplantation 20100201

• Extended-schedule dose-dense temozolomide in refractory gliomas.

  Journal of neuro-oncology 20100201

• Protein tyrosine phosphatases in glioma biology.

  Acta neuropathologica 20100201

• Consensus conference on the use of 90-yttrium-ibritumomab tiuxetan therapy in clinical practice. A project of the Italian society of hematology.

  American journal of hematology 20100201

• Predictive value of (18)F-FDG hybrid PET/CT for the clinical outcome in patients with non-Hodgkin's lymphoma prior to and after autologous stem cell transplantation.

  Hematology (Amsterdam, Netherlands) 20100201

• Inhibition of thromboxane synthase activity improves glioblastoma response to alkylation chemotherapy.

  Translational oncology 20100201

• Targeting A20 decreases glioma stem cell survival and tumor growth.

  PLoS biology 20100201

• Clinical features, management and outcomes of high-grade glioma patients in Ramathibodi Hospital.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20100201

• [Chemotherapeutic wafers in treatment of malignant cerebral glioma. Assessment of a Cochrane review].

  Ugeskrift for laeger 20100118

• Inhibition of 90-kD heat shock protein potentiates the cytotoxicity of chemotherapeutic agents in human glioma cells.

  Journal of neurosurgery 20100101

• Expression of tyrosine hydroxylase increases the resistance of human neuroblastoma cells to oxidative insults.

  Toxicological sciences : an official journal of the Society of Toxicology 20100101

• Thiol-metabolizing proteins and endothelial redox state: differential modulation of eNOS and biopterin pathways.

  American journal of physiology. Heart and circulatory physiology 20100101

• The role of emerging and investigational therapies for metastatic brain tumors: a systematic review and evidence-based clinical practice guideline of selected topics.

  Journal of neuro-oncology 20100101

• Comparison of influence of carmustine and new proline analog of nitrosourea on antioxidant system in breast carcinoma cells (MCF-7).

  Drug and chemical toxicology 20100101

• Prognostic impact of proliferative index determined by quantitative image analysis and the International Prognostic Index in patients with mantle cell lymphoma.

  Annals of oncology : official journal of the European Society for Medical Oncology 20100101

• Candida meningitis post Gliadel wafer placement successfully treated with intrathecal and intravenous amphotericin B.

  The Annals of pharmacotherapy 20100101

• Repeated spontaneous pregnancies and successful deliveries after repeated autologous stem cell transplantation and GnRH-agonist treatment.

  The oncologist 20100101

• Current multiple myeloma treatment strategies with novel agents: a European perspective.

  The oncologist 20100101

• BCNU for recurrent glioblastoma multiforme: efficacy, toxicity and prognostic factors.

  BMC cancer 20100101

• Metabolism of a lipid nanoemulsion resembling low-density lipoprotein in patients with grade iii obesity.

  Clinics (Sao Paulo, Brazil) 20100101

• A mouse model for the Sézary syndrome.

  Journal of experimental & clinical cancer research : CR 20100101

• Incorporating BCNU wafers into malignant glioma treatment: European case studies.

  Clinical drug investigation 20100101

• Promoter methylation analysis of O6-methylguanine-DNA methyltransferase in glioblastoma: detection by locked nucleic acid based quantitative PCR using an imprinted gene (SNURF) as a reference.

  BMC cancer 20100101

• Role of senescence and mitotic catastrophe in cancer therapy.

  Cell division 20100101

• Progress on antiangiogenic therapy for patients with malignant glioma.

  Journal of oncology 20100101

• Melanoma: a model for testing new agents in combination therapies.

  Journal of translational medicine 20100101

• Antiangiogenic therapy and mechanisms of tumor resistance in malignant glioma.

  Journal of oncology 20100101

• Interleukin-15 affects patient survival through natural killer cell recovery after autologous hematopoietic stem cell transplantation for non-Hodgkin lymphomas.

  Clinical & developmental immunology 20100101

• Metastatic gliosarcoma with a unique presentation and progression: case report and review of the literature.

  Clinical neuropathology 20100101

• Troglitazone reduces glyoxalase I protein expression in glioma and potentiates the effects of chemotherapeutic agents.

  Journal of oncology 20100101

• Cyclophosphamide-metabolizing enzyme polymorphisms and survival outcomes after adjuvant chemotherapy for node-positive breast cancer: a retrospective cohort study.

  Breast cancer research : BCR 20100101

• Daily intake of antioxidants in relation to survival among adult patients diagnosed with malignant glioma.

  BMC cancer 20100101

• Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics.

  Molecular cancer 20100101

• Carmustine and methotrexate in combination after whole brain radiation therapy in breast cancer patients presenting with brain metastases: a retrospective study.

  BMC cancer 20100101

• CyberKnife enhanced conventionally fractionated chemoradiation for high grade glioma in close proximity to critical structures.

  Journal of hematology & oncology 20100101

• Pharmacokinetics of rituximab in patients with CD20 positive B-cell malignancies.

  Human antibodies 20100101

• New treatment options in the management of glioblastoma multiforme: a focus on bevacizumab.

  OncoTargets and therapy 20100101

• Ring chromosome 18 abnormality in acute myelogenous leukemia: the clinical dilemma.

  Journal of hematology & oncology 20100101

• Mesenchymal migration as a therapeutic target in glioblastoma.

  Journal of oncology 20100101

• Impact of adjuvant chemotherapy for gliomatosis cerebri.

  BMC cancer 20100101

• MRP3: a molecular target for human glioblastoma multiforme immunotherapy.

  BMC cancer 20100101

• Polymorphic nucleic Acid binding of bioactive isoquinoline alkaloids and their role in cancer.

  Journal of nucleic acids 20100101

• Randomized phase II study evaluating a carbon ion boost applied after combined radiochemotherapy with temozolomide versus a proton boost after radiochemotherapy with temozolomide in patients with primary glioblastoma: the CLEOPATRA trial.

  BMC cancer 20100101

• Temozolomide in malignant glioma.

  OncoTargets and therapy 20100101

• Elevated expression of Dickkopf-1 increases the sensitivity of human glioma cell line SHG44 to BCNU.

  Journal of experimental & clinical cancer research : CR 20100101

• Randomised phase I/II study to evaluate carbon ion radiotherapy versus fractionated stereotactic radiotherapy in patients with recurrent or progressive gliomas: the CINDERELLA trial.

  BMC cancer 20100101

• Nano to micro delivery systems: targeting angiogenesis in brain tumors.

  Journal of angiogenesis research 20100101

• Unexpected high response rate to traditional therapy after dendritic cell-based vaccine in advanced melanoma: update of clinical outcome and subgroup analysis.

  Clinical & developmental immunology 20100101

• Development of a Novel Fluorescence Assay Based on the Use of the Thrombin-Binding Aptamer for the Detection of O-Alkylguanine-DNA Alkyltransferase Activity.

  Journal of nucleic acids 20100101

• Cellular and vaccine therapeutic approaches for gliomas.

  Journal of translational medicine 20100101

• Modification of composition of a nanoemulsion with different cholesteryl ester molecular species: effects on stability, peroxidation, and cell uptake.

  International journal of nanomedicine 20100101

• Equivalence of pegfilgrastim and filgrastim in lymphoma patients treated with BEAM followed by autologous stem cell transplantation.

  Oncology 20100101

• The use of chemotherapy regimens carrying a moderate or high risk of febrile neutropenia and the corresponding management of febrile neutropenia: an expert survey in breast cancer and non-Hodgkin's lymphoma.

  BMC cancer 20100101

• DNA damage induced by alkylating agents and repair pathways.

  Journal of nucleic acids 20100101

• Role of bevacizumab therapy in the management of glioblastoma.

  Cancer management and research 20100101

• Rituximab in the treatment of B-cell non-Hodgkin lymphoma, focus on outcomes and comparative effectiveness.

  ClinicoEconomics and outcomes research : CEOR 20100101

• Novel therapies delay the progression of smoldering multiple myeloma: Case report and discussion.

  Ecancermedicalscience 20100101

• Immunochemotherapy and autologous stem-cell transplantation for untreated patients with mantle-cell lymphoma: CALGB 59909.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091220

• Autologous stem cell transplant in a patient with Down syndrome and relapsed Hodgkin lymphoma.

  Pediatric blood & cancer 20091215

• [Clostridial brain abscess after glioblastoma resection: case report and critical review of the literature].

  Neuro-Chirurgie 20091201

• Down-regulation of lipocalin 2 contributes to chemoresistance in glioblastoma cells.

  Journal of neurochemistry 20091201

• Interleukin-2 and granulocyte-macrophage-colony-stimulating factor immunomodulation with high-dose chemotherapy and autologous hematopoietic stem cell transplantation for patients with metastatic breast cancer.

  International journal of hematology 20091201

• Antiangiogenesis in recurrent glioblastoma: proof of principle.

  Neurology international 20091116

• Current data and strategy in glioblastoma multiforme.

  Journal of medicine and life 20091115

• Intracavitary carmustine polymer implantation as an adjunct to palliative metastatic vertebral column tumors.

  Surgical neurology 20091101

• Non-PEGylated liposomes for convection-enhanced delivery of topotecan and gadodiamide in malignant glioma: initial experience.

  Journal of neuro-oncology 20091101

• Health related quality of life and cognitive status in patients with glioblastoma multiforme receiving escalating doses of conformal three dimensional radiation on RTOG 98-03.

  Journal of neuro-oncology 20091101

• Proline analogue of nitrosourea as a new cytotoxic prodrug.

  Archiv der Pharmazie 20091101

• Determination of reduced nicotinamide adenine dinucleotide phosphate concentration using high-performance liquid chromatography with fluorescence detection: ratio of the reduced form as a biomarker of oxidative stress.

  Biological & pharmaceutical bulletin 20091101

• Prognostic impact of O6-methylguanine-DNA methyltransferase silencing in patients with recurrent glioblastoma multiforme who undergo surgery and carmustine wafer implantation: a prospective patient cohort.

  Cancer 20091015

• Self-reported experience of mucositis in cancer patients who underwent conditioning regimen and stem cell transplantation.

  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20091001

• Role of convective flow in carmustine delivery to a brain tumor.

  Pharmaceutical research 20091001

• Insights into pharmacotherapy of malignant glioma in adults.

  Expert opinion on pharmacotherapy 20091001

• Palonosetron in prevention of nausea and vomiting after highly emetogenic chemotherapy before haematopoietic stem cell transplantation-single center experience.

  Transplantation proceedings 20091001

• Clinical activity of laromustine (Onrigin™) in hematologic malignancies.

  Expert review of hematology 20091001

• Fotemustine as second-line treatment for recurrent or progressive glioblastoma after concomitant and/or adjuvant temozolomide: a phase II trial of Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO).

  Cancer chemotherapy and pharmacology 20090901

• Carbonate and carbamate derivatives of 4-demethylpenclomedine as novel anticancer agents.

  Cancer chemotherapy and pharmacology 20090901

• Gingko biloba leaf extract induces oxidative stress in carcinoma HSC-2 cells.

  Toxicology in vitro : an international journal published in association with BIBRA 20090901

• Profiling patterns of glutathione reductase inhibition by the natural product illudin S and its acylfulvene analogues.

  Molecular bioSystems 20090901

• I-Tositumomab in lymphoma.

  Current oncology (Toronto, Ont.) 20090901

• Two phase II trials of temozolomide with interferon-alpha2b (pegylated and non-pegylated) in patients with recurrent glioblastoma multiforme.

  British journal of cancer 20090818

• Chemotherapeutic drug transport to brain tumor.

  Journal of controlled release : official journal of the Controlled Release Society 20090804

• Cisplatinum and BCNU chemotherapy in primary glioblastoma patients.

  Journal of neuro-oncology 20090801

• Glutathione disulfide induces neural cell death via a 12-lipoxygenase pathway.

  Cell death and differentiation 20090801

• Overall survival of newly diagnosed glioblastoma patients receiving carmustine wafers followed by radiation and concurrent temozolomide plus rotational multiagent chemotherapy.

  Cancer 20090801

• pY-STAT3 and p53 expression predict outcome for poor prognosis diffuse large B-cell lymphoma treated with high dose chemotherapy and autologous stem cell transplantation.

  Leukemia & lymphoma 20090801

• Small molecules and targeted therapies in distant metastatic disease.

  Annals of oncology : official journal of the European Society for Medical Oncology 20090801

• Protective mechanism of quercetin and rutin using glutathione metabolism on HO-induced oxidative stress in HepG2 cells.

  Annals of the New York Academy of Sciences 20090801

• Glutathione homeostasis in ventricular myocytes from rat hearts with chronic myocardial infarction.

  Experimental physiology 20090701

• In vivo selection of hematopoietic progenitor cells and temozolomide dose intensification in rhesus macaques through lentiviral transduction with a drug resistance gene.

  The Journal of clinical investigation 20090701

• High-dose immunoembolization: survival benefit in patients with hepatic metastases from uveal melanoma.

  Radiology 20090701

• [Treatment of glioma with temozolomide].

  Brain and nerve = Shinkei kenkyu no shinpo 20090701

• Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents.

  Toxicology and applied pharmacology 20090615

• Amelioration of murine beta-thalassemia through drug selection of hematopoietic stem cells transduced with a lentiviral vector encoding both gamma-globin and the MGMT drug-resistance gene.

  Blood 20090604

• Peroxiredoxin 2 and peroxidase enzymatic activity of mammalian spermatozoa.

  Biology of reproduction 20090601

• Bifunctional DNA alkylator 1,3-bis(2-chloroethyl)-1-nitrosourea activates the ATR-Chk1 pathway independently of the mismatch repair pathway.

  Molecular pharmacology 20090601

• Impairment of APE1 function enhances cellular sensitivity to clinically relevant alkylators and antimetabolites.

  Molecular cancer research : MCR 20090601

• A network of conserved damage survival pathways revealed by a genomic RNAi screen.

  PLoS genetics 20090601

• Molecular markers of tumor progression in melanoma.

  Current genomics 20090601

• The treatment of multiple myeloma using vincristine, carmustine, melphalan, cyclophosphamide, and prednisone (VBMCP) alternating with high-dose cyclophosphamide and alpha(2)beta interferon versus VBMCP: results of a phase III Eastern Cooperative Oncology Group Study E5A93.

  Cancer 20090515

• Enhancing the antitumor activity of adriamycin and ionizing radiation.

  Cancer research 20090515

• Pegfilgrastim and daily granulocyte colony-stimulating factor: patterns of use and neutropenia-related outcomes in cancer patients in Spain--results of the LEARN Study.

  European journal of cancer care 20090501

• [Stem cell therapy in multiple sclerosis: a clinical update].

  Zeitschrift fur Rheumatologie 20090501

• Methylguanine DNA methyltransferase-mediated drug resistance-based selective enrichment and engraftment of transplanted stem cells in skeletal muscle.

  Stem cells (Dayton, Ohio) 20090501

• Syngeneic transplant in mantle cell lymphoma: a rare event and review of the literature.

  Clinical advances in hematology & oncology : H&O 20090501

• A successful treatment of relapsed primary CNS lymphoma patient with intraventricular rituximab followed by high-dose chemotherapy with autologous stem cell rescue.

  Yonsei medical journal 20090430

• A phase I study of extended dosing with lomeguatrib with temozolomide in patients with advanced melanoma.

  British journal of cancer 20090421

• O(6)-methylguanine-DNA methyltransferase depletion and DNA damage in patients with melanoma treated with temozolomide alone or with lomeguatrib.

  British journal of cancer 20090421

• Bevacizumab for recurrent alkylator-refractory anaplastic oligodendroglioma.

  Cancer 20090415

• Fenofibrate-loaded PLGA microparticles: effects on ischemic stroke.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090411

• Treatment of oral mucositis after peripheral blood SCT with ATL-104 mouthwash: results from a randomized, double-blind, placebo-controlled trial.

  Bone marrow transplantation 20090401

• delta-Aminolevulinate dehydratase activity and oxidative stress during melphalan and cyclophosphamide-BCNU-etoposide (CBV) conditioning regimens in autologous bone marrow transplantation patients.

  Pharmacological research 20090401

• Yttrium-90 ibritumomab tiuxetan doses calculated to deliver up to 15 Gy to critical organs may be safely combined with high-dose BEAM and autologous transplantation in relapsed or refractory B-cell non-Hodgkin's lymphoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090401

• Expression of layer-specific markers in the adult neocortex of BCNU-Treated rat, a model of cortical dysplasia.

  Neuroscience 20090317

• The redox state of glutathione regulates the hypoxic induction of HIF-1.

  European journal of pharmacology 20090315

• Randomized phase II trial of erlotinib versus temozolomide or carmustine in recurrent glioblastoma: EORTC brain tumor group study 26034.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090310

• BCNU-sequestration by metallothioneins may contribute to resistance in a medulloblastoma cell line.

  Cancer chemotherapy and pharmacology 20090301

• Phase I three-dimensional conformal radiation dose escalation study in newly diagnosed glioblastoma: Radiation Therapy Oncology Group Trial 98-03.

  International journal of radiation oncology, biology, physics 20090301

• Association of preoperative depression and survival after resection of malignant brain astrocytoma.

  Surgical neurology 20090301

• Gliadel (BCNU) wafer plus concomitant temozolomide therapy after primary resection of glioblastoma multiforme.

  Journal of neurosurgery 20090301

• Glial cell-line derived neurotrophic factor (GDNF) family of ligands confer chemoresistance in a ligand-specific fashion in malignant gliomas.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20090301

• Monitoring of tumor response to chemotherapy in vivo by a novel small-molecule detector of apoptosis.

  Apoptosis : an international journal on programmed cell death 20090301

• Mass selection of ions from beams using waveform isolation in radiofrequency quadrupoles.

  Analytical chemistry 20090301

• Reduced-intensity conditioning regimen workshop: defining the dose spectrum. Report of a workshop convened by the center for international blood and marrow transplant research.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20090301

• Incidence and risk factors for second cancers after autologous hematopoietic cell transplantation for aggressive non-Hodgkin lymphoma.

  Leukemia & lymphoma 20090301

• Temozolomide and carmustine cause large-scale heterochromatin reorganization in glioma cells.

  Biochemical and biophysical research communications 20090206

• Experience with irinotecan for the treatment of malignant glioma.

  Neuro-oncology 20090201

• DNA alkylation products formed by 1-(2-chloroethyl)-1-nitrosourea as molecular dosimeters of therapeutic response.

  Journal of neuro-oncology 20090201

• High-dose Ara-C and beam with autograft rescue in R-CHOP responsive mantle cell lymphoma patients.

  British journal of haematology 20090201

• Pseudo-bowel obstruction due to varicella zoster virus infection after autologous stem cell transplantation.

  American journal of hematology 20090201

• Growth inhibition against intracranial C6 glioma cells by stereotactic delivery of BCNU by controlled release from poly(D,L-lactic acid) nanoparticles.

  Technology in cancer research & treatment 20090201

• Phase II trial of Gliadel plus O6-benzylguanine in adults with recurrent glioblastoma multiforme.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090201

• Favorable outcome of primary CNS anaplastic large cell lymphoma in an immunocompetent patient.

  Journal of pediatric hematology/oncology 20090201

• [Interdigitating dendritic cell sarcoma of lower extremities resistant to high dose chemotherapy BEAM with peripheral blood stem cell transplantation].

  Vnitrni lekarstvi 20090201

• Characterization of a novel dithiocarbamate glutathione reductase inhibitor and its use as a tool to modulate intracellular glutathione.

  The Journal of biological chemistry 20090130

• Metallothionein attenuates carmustine-induced oxidative stress and protects against pulmonary fibrosis in rats.

  Archives of toxicology 20090101

• The Prospective Oral Mucositis Audit: relationship of severe oral mucositis with clinical and medical resource use outcomes in patients receiving high-dose melphalan or BEAM-conditioning chemotherapy and autologous SCT.

  Bone marrow transplantation 20090101

• Increased risk for invasive aspergillosis in patients with lymphoproliferative diseases after autologous hematopoietic SCT.

  Bone marrow transplantation 20090101

• Comparative analysis of temozolomide (TMZ) versus 1,3-bis (2-chloroethyl)-1 nitrosourea (BCNU) in newly diagnosed glioblastoma multiforme (GBM) patients.

  Journal of neuro-oncology 20090101

• What is the translational efficacy of chemotherapeutic drug research in neuro-oncology? A systematic review and meta-analysis of the efficacy of BCNU and CCNU in animal models of glioma.

  Journal of neuro-oncology 20090101

• Independent association of extent of resection with survival in patients with malignant brain astrocytoma.

  Journal of neurosurgery 20090101

• Autologous stem-cell transplantation as first-line therapy in peripheral T-cell lymphomas: results of a prospective multicenter study.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090101

• Suppression of HLA expression by lentivirus-mediated gene transfer of siRNA cassettes and in vivo chemoselection to enhance hematopoietic stem cell transplantation.

  Immunologic research 20090101

• [Diagnostic and treatment delays do not modify the treatment outcome of patients with multiform glioblastoma].

  Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20090101

• Drugs targeting the mitochondrial pore act as cytotoxic and cytostatic agents in temozolomide-resistant glioma cells.

  Journal of translational medicine 20090101

• Localized BCNU chemotherapy and the multimodal management of malignant glioma.

  Current medical research and opinion 20090101

• Possible novel therapy for malignant gliomas with secretable trimeric TRAIL.

  PloS one 20090101

• Homogeneous MGMT immunoreactivity correlates with an unmethylated MGMT promoter status in brain metastases of various solid tumors.

  PloS one 20090101

• Long term survivors with metastatic pancreatic adenocarcinoma treated with gemcitabine: a retrospective analysis.

  Journal of hematology & oncology 20090101

• Stereotactic radiosurgery for glioblastoma: retrospective analysis.

  Radiation oncology (London, England) 20090101

• Treatment of recurrent malignant gliomas with fotemustine monotherapy: impact of dose and correlation with MGMT promoter methylation.

  BMC cancer 20090101

• Delta-ALA-D activity is a reliable marker for oxidative stress in bone marrow transplant patients.

  BMC cancer 20090101

• Identification and characterization of inhibitors of human apurinic/apyrimidinic endonuclease APE1.

  PloS one 20090101

• Primary non-Hodgkin's lymphoma of the infratemporal fossa: a rare case report.

  Head & neck oncology 20090101

• Phase II assessment of talabostat and cisplatin in second-line stage IV melanoma.

  BMC cancer 20090101

• Current available therapies and future directions in the treatment of malignant gliomas.

  Biologics : targets & therapy 20090101

• Transcriptome and proteome analyses of adaptive responses to methyl methanesulfonate in Escherichia coli K-12 and ada mutant strains.

  BMC microbiology 20090101

• Drugs associated with more suicidal ideations are also associated with more suicide attempts.

  PloS one 20090101

• Inherited glutathione reductase deficiency and Plasmodium falciparum malaria--a case study.

  PloS one 20090101

• A dosimetric comparison of four treatment planning methods for high grade glioma.

  Radiation oncology (London, England) 20090101

• Integrated-boost IMRT or 3-D-CRT using FET-PET based auto-contoured target volume delineation for glioblastoma multiforme--a dosimetric comparison.

  Radiation oncology (London, England) 20090101

• Prediction of pharmacological and xenobiotic responses to drugs based on time course gene expression profiles.

  PloS one 20090101

• Standard therapy of advanced Hodgkin lymphoma.

  Hematology. American Society of Hematology. Education Program 20090101

• Introduction of hypermatrix and operator notation into a discrete mathematics simulation model of malignant tumour response to therapeutic schemes in vivo. Some operator properties.

  Cancer informatics 20090101

• Recursive partitioning analysis of prognostic factors in WHO grade III glioma patients treated with radiotherapy or radiotherapy plus chemotherapy.

  BMC cancer 20090101

• Marking the onset of oxidative stress: biomarkers and novel strategies.

  Oxidative medicine and cellular longevity 20090101

• Metallothionein induction reduces caspase-3 activity and TNFalpha levels with preservation of cognitive function and intact hippocampal neurons in carmustine-treated rats.

  Oxidative medicine and cellular longevity 20090101

• Promising treatments of tomorrow for multiple sclerosis.

  Annals of Indian Academy of Neurology 20090101

• Specific factors influence the success of autologous and allogeneic hematopoietic stem cell transplantation.

  Oxidative medicine and cellular longevity 20090101

• Synergistic potentiation of D-fraction with vitamin C as possible alternative approach for cancer therapy.

  International journal of general medicine 20090101

• Role of bendamustine in the treatment of chronic lymphocytic leukemia.

  OncoTargets and therapy 20090101

• Targeted therapy in the treatment of malignant gliomas.

  OncoTargets and therapy 20090101

• Update on the rational use of Y-ibritumomab tiuxetan in the treatment of follicular lymphoma.

  OncoTargets and therapy 20090101

• Update on the rational use of tositumomab and iodine-131 tositumomab radioimmunotherapy for the treatment of non-Hodgkin's lymphoma.

  OncoTargets and therapy 20090101

• Bendamustine in the treatment of non-Hodgkin's lymphomas.

  OncoTargets and therapy 20090101

• Temozolomide: The evidence for its therapeutic efficacy in malignant astrocytomas.

  Core evidence 20090101

• New therapies for recurrent glioblastomas.

  F1000 medicine reports 20090101

• Integrated care and optimal management of pulmonary arterial hypertension.

  Journal of multidisciplinary healthcare 20090101

• Gene therapy in thalassemia and hemoglobinopathies.

  Mediterranean journal of hematology and infectious diseases 20090101

• Early versus late intensification for patients with high-risk Hodgkin lymphoma-3 cycles of intensive chemotherapy plus low-dose lymph node radiation therapy versus 4 cycles of combined doxorubicin, bleomycin, vinblastine, and dacarbazine plus myeloablative chemotherapy with autologous stem cell transplantation: five-year results of a randomized trial on behalf of the GOELAMS Group.

  Cancer 20081215

• Influence of pre- and post-transplantation responses on outcome of patients with multiple myeloma: sequential improvement of response and achievement of complete response are associated with longer survival.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081210

• Three weeks release BCNU loaded hydrophilic-PLGA microspheres for interstitial chemotherapy: Development and activity against human glioblastoma cells.

  Journal of microencapsulation 20081201

• Phase I analysis of BCNU-impregnated biodegradable polymer wafers followed by systemic interferon alfa-2b in adults with recurrent glioblastoma multiforme.

  Journal of neuro-oncology 20081201

• Development of an O(6)-alkylguanine-DNA alkyltransferase assay based on covalent transfer of the benzyl moiety from [benzene-3H]O(6)-benzylguanine to the protein.

  Analytical biochemistry 20081201

• Myeloablative chemotherapy with autologous bone marrow rescue in children and adolescents with recurrent malignant astrocytoma: outcome compared with conventional chemotherapy: a report from the Children's Oncology Group.

  Pediatric blood & cancer 20081201

• Autologous stem cell transplantation for diffuse large B-cell lymphoma with residual extranodal involvement.

  The Korean journal of internal medicine 20081201

• Prospective trial of gross-total resection with Gliadel wafers followed by early postoperative Gamma Knife radiosurgery and conformal fractionated radiotherapy as the initial treatment for patients with radiographically suspected, newly diagnosed glioblastoma multiforme.

  Journal of neurosurgery 20081201

• Multiparameter flow cytometric remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation.

  Blood 20081115

• Going with the flow, and beyond, in myeloma.

  Blood 20081115

• Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

  Journal of medicinal chemistry 20081113

• Pretransplantation positron emission tomography scan is the main predictor of autologous stem cell transplantation outcome in aggressive B-cell non-Hodgkin lymphoma.

  Cancer 20081101

• Safety profile of carmustine wafers in malignant glioma: a review of controlled trials and a decade of clinical experience.

  Current medical research and opinion 20081101

• Use of Gliadel (BCNU) wafer in the surgical treatment of malignant glioma: a 10-year institutional experience.

  Annals of surgical oncology 20081001

• Myelomatous meningitis.

  European journal of haematology 20081001

• Effect of the dose per body weight of conditioning chemotherapy on severity of mucositis and risk of relapse after autologous haematopoietic stem cell transplantation in relapsed diffuse large B cell lymphoma.

  British journal of haematology 20081001

• Effects, in an in-vivo model system, of 1,2,3,4-tetrahydroisoquinoline on glioma.

  Anti-cancer drugs 20081001

• High-dose chemotherapy with BEAM or Busulphan/Melphalan and Thiotepa followed by hematopoietic cell transplantation in malignant lymphoma.

  Leukemia & lymphoma 20081001

• Intrathecal corticosteroids might slow Alzheimer's disease progression.

  Neuropsychiatric disease and treatment 20081001

• Pharmacologic blockade of chloride channel synergistically enhances apoptosis of chemotherapeutic drug-resistant cancer stem cells.

  Biochemical and biophysical research communications 20080905

• Late-onset neutropenia following viral bone marrow depression after rituximab therapy.

  Annals of hematology 20080901

• Assessment of a balloon-tipped catheter modified for intracerebral convection-enhanced delivery.

  Journal of neuro-oncology 20080901

• Relationship of glioblastoma multiforme to the lateral ventricles predicts survival following tumor resection.

  Journal of neuro-oncology 20080901

• Keratinocyte growth factor is effective in the prevention of intestinal mucositis in patients with hematological malignancies treated with high-dose chemotherapy and autologous hematopoietic SCT: a video-capsule endoscopy study.

  Bone marrow transplantation 20080901

• [Clinical outcome 6 years after autologous hematopoietic stem cell transplantation in multiple sclerosis].

  Neurologia (Barcelona, Spain) 20080901

• [A case of interstitial pneumonia caused by carmustine.].

  Zhongguo fei ai za zhi = Chinese journal of lung cancer 20080820

• Tumour-targeted nanomedicines: principles and practice.

  British journal of cancer 20080805

• Transcriptional repression of O6-methylguanine DNA methyltransferase gene rendering cells hypersensitive to N,N'-bis(2-chloroethyl)-N-nitrosurea in camptothecin-resistant cells.

  Molecular pharmacology 20080801

• External beam irradiation and the combination of cisplatin and carmustine followed by carmustine alone for the treatment of high-grade glioma: a phase 2 Southwest Oncology Group trial.

  Cancer 20080801

• Polyanhydrides as localized drug delivery carrier: an update.

  Expert opinion on drug delivery 20080801

• Bendamustine HCL for the treatment of relapsed indolent non-Hodgkin's lymphoma.

  Therapeutics and clinical risk management 20080801

• Chemotherapeutic wafers for High Grade Glioma.

  The Cochrane database of systematic reviews 20080716

• Reduced-toxicity conditioning with fludarabine, BCNU, and melphalan in allogeneic hematopoietic cell transplantation: particular activity against advanced hematologic malignancies.

  Blood 20080715

• Noninvasive assessment of E2F-1-mediated transcriptional regulation in vivo.

  Cancer research 20080715

• Meta-analyses of chemotherapy for locally advanced and metastatic pancreatic cancer: results of secondary end points analyses.

  British journal of cancer 20080708

• Long-term outcome of autologous stem-cell transplantation in relapsed or refractory Hodgkin's lymphoma.

  Annals of oncology : official journal of the European Society for Medical Oncology 20080701

• A retrospective study of the safety of BCNU wafers with concurrent temozolomide and radiotherapy and adjuvant temozolomide for newly diagnosed glioblastoma patients.

  Journal of neuro-oncology 20080701

• Carmustine-resistant cancer cells are sensitized to temozolomide as a result of enhanced mismatch repair during the development of carmustine resistance.

  Molecular pharmacology 20080701

• Comorbidities, not age, impact outcomes in autologous stem cell transplant for relapsed non-Hodgkin lymphoma.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20080701

• Heterogeneity of human glioblastoma: glutathione-S-transferase and methylguanine-methyltransferase.

  Cancer investigation 20080701

• Skin directed therapy for mycosis fungoides: a review.

  Journal of drugs in dermatology : JDD 20080701

• Prognostic molecular markers with no impact on decision-making: the paradox of gliomas based on a prospective study.

  British journal of cancer 20080603

• A possible role for intracellular GSH in spontaneous reaction of a cysteine (T338C) engineered into the Cystic Fibrosis Transmembrane Conductance Regulator.

  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20080601

• Chylous ascites secondary to B-cell non Hodgkin's lymphoma in a patient with the acquired immune deficiency syndrome (AIDS).

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20080601

• Adjuvant dibromodulcitol and BCNU chemotherapy in anaplastic astrocytoma: results of a randomised European Organisation for Research and Treatment of Cancer phase III study (EORTC study 26882).

  European journal of cancer (Oxford, England : 1990) 20080601

• Oxidoreductase regulation of Kv currents in rat ventricle.

  Journal of molecular and cellular cardiology 20080601

• [Chemotherapy and renal toxicity].

  Bulletin du cancer 20080528

• A phase II trial of lomeguatrib and temozolomide in metastatic colorectal cancer.

  British journal of cancer 20080520

• Altered spatial distribution of PV-cortical cells and dysmorphic neurons in the somatosensory cortex of BCNU-treated rat model of cortical dysplasia.

  Epilepsia 20080501

• Peripheral blood stem cell transplant for POEMS syndrome is associated with high rates of engraftment syndrome.

  European journal of haematology 20080501

• Controlled-release implant system formulated using biodegradable hemostatic gauze as scaffold.

  International journal of pharmaceutics 20080501

• Nitrosourea efficacy in high-grade glioma: a survival gain analysis summarizing 504 cohorts with 24193 patients.

  Journal of neuro-oncology 20080501

• Intensive chemotherapy (high-dose CHOP/ESHAP regimen) followed by autologous stem-cell transplantation in previously untreated patients with peripheral T-cell lymphoma.

  Annals of oncology : official journal of the European Society for Medical Oncology 20080501

• Intracavitary chemotherapy (Gliadel) and oral low-dose etoposide for recurrent anaplastic ependymoma.

  Oncology reports 20080501

• High-dose chemotherapy with autologous stem cell transplantation in adults with recurrent embryonal tumors of the central nervous system.

  Cancer 20080415

• Intensive conditioning regimen of etoposide (VP-16), cyclophosphamide and carmustine (VCB) followed by autologous hematopoietic stem cell transplantation for relapsed and refractory Hodgkin's lymphoma.

  Bone marrow transplantation 20080401

• Theaflavin-3,3'-digallate, a component of black tea: an inducer of oxidative stress and apoptosis.

  Toxicology in vitro : an international journal published in association with BIBRA 20080401

• Outcome of BEAM-autologous and BEAM-alemtuzumab allogeneic transplantation in relapsed advanced stage follicular lymphoma.

  British journal of haematology 20080401

• Prospective oral mucositis audit: oral mucositis in patients receiving high-dose melphalan or BEAM conditioning chemotherapy--European Blood and Marrow Transplantation Mucositis Advisory Group.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080320

• Successful treatment of a child with late-onset T-cell post-transplant lymphoproliferative disorder/lymphoma.

  Pediatric blood & cancer 20080301

• Time-dependent effect of non-Hodgkin's lymphoma grade on disease-free survival of relapsed/refractory patients treated with high-dose chemotherapy plus autotransplantation.

  Contemporary clinical trials 20080301

• Phase 1 trial of O6-benzylguanine and BCNU in children with CNS tumors: a Children's Oncology Group study.

  Pediatric blood & cancer 20080301

• Dose-escalated CHOP and tailored intensification with IFE according to early response and followed by BEAM/autologous stem-cell transplantation in poor-risk aggressive B-cell lymphoma: a prospective study from the GEL-TAMO Study Group.

  European journal of haematology 20080301

• Increased oxidative stress created by adenoviral MnSOD or CuZnSOD plus BCNU (1,3-bis(2-chloroethyl)-1-nitrosourea) inhibits breast cancer cell growth.

  Free radical biology & medicine 20080301

• Bone marrow-derived cells exhibiting lung epithelial cell characteristics are enriched in vivo using methylguanine DNA methyltransferase-mediated drug resistance.

  Stem cells (Dayton, Ohio) 20080301

• Synthesis and characterization of DNA containing an N1-2'-deoxyinosine-ethyl-N3-thymidine interstrand cross-link: a structural mimic of the cross-link formed by 1,3-bis-(2-chloroethyl)-1-nitrosourea.

  Chemical research in toxicology 20080301

• A phase 2 pilot study of pegfilgrastim and filgrastim for mobilizing peripheral blood progenitor cells in patients with non-Hodgkin's lymphoma receiving chemotherapy.

  Haematologica 20080301

• Transient global amnesia associated with the infusion of DMSO-cryopreserved autologous peripheral blood stem cells.

  Haematologica 20080301

• Carmustine wafers: localized delivery of chemotherapeutic agents in CNS malignancies.

  Expert review of anticancer therapy 20080301

• Clinical uses of GM-CSF, a critical appraisal and update.

  Biologics : targets & therapy 20080301

• A safety and efficacy study of local delivery of interleukin-12 transgene by PPC polymer in a model of experimental glioma.

  Anti-cancer drugs 20080201

• Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment.

  European journal of clinical pharmacology 20080201

• Safety and efficacy of permanent iodine-125 seed implants and carmustine wafers in patients with recurrent glioblastoma multiforme.

  Journal of neurosurgery 20080201

• [Chemosensitivity test on brain tumors].

  Neurocirugia (Asturias, Spain) 20080201

• Epigenetic silencing of telomerase and a non-alkylating agent as a novel therapeutic approach for glioma.

  Brain research 20080110

• High-dose therapy and autologous stem-cell transplantation in angioimmunoblastic lymphoma: complete remission at transplantation is the major determinant of Outcome-Lymphoma Working Party of the European Group for Blood and Marrow Transplantation.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080110

• Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy.

  Cancer immunology, immunotherapy : CII 20080101

• Transient cerebral hypoperfusion enhances intraarterial carmustine deposition into brain tissue.

  Journal of neuro-oncology 20080101

• BEAC or BEAM high-dose chemotherapy followed by autologous stem cell transplantation in non-Hodgkin's lymphoma patients: comparative analysis of efficacy and toxicity.

  Annals of hematology 20080101

• Phase II trial of a transplantation regimen of yttrium-90 ibritumomab tiuxetan and high-dose chemotherapy in patients with non-Hodgkin's lymphoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080101

• Carmustine implants for the treatment of newly diagnosed high-grade gliomas: a cost-utility analysis.

  PharmacoEconomics 20080101

• Cannabinoids as potential new therapy for the treatment of gliomas.

  Expert review of neurotherapeutics 20080101

• Prospective single-arm study of 72 Gy hyperfractionated radiation therapy and combination chemotherapy for anaplastic astrocytomas.

  BMC cancer 20080101

• Cutaneous lymphoma.

  Current problems in cancer 20080101

• BCNU toxicity presenting with a large pericardial and pleural effusion.

  Annals of transplantation 20080101

• Idiopathic pulmonary fibrosis.

  Orphanet journal of rare diseases 20080101

• Systematic review of the clinical effect of glucocorticoids on nonhematologic malignancy.

  BMC cancer 20080101

• Chemotherapy-induced bystander effect in response to several chloroethylnitrosoureas: an origin independent of DNA damage?

  Anticancer research 20080101

• How chemotherapy damages the central nervous system.

  Journal of biology 20080101

• Proline-linked nitrosoureas as prolidase-convertible prodrugs in human breast cancer cells.

  Pharmacological reports : PR 20080101

• Bcl-2 expression is not associated with survival in metastatic cutaneous melanoma: a historical cohort study.

  World journal of surgical oncology 20080101

• Over-expression of Skp2 is associated with resistance to preoperative doxorubicin-based chemotherapy in primary breast cancer.

  Breast cancer research : BCR 20080101

• Cytotoxic and apoptotic effects of bortezomib and gefitinib compared to alkylating agents on human glioblastoma cells.

  Journal of experimental therapeutics & oncology 20080101

• [Postoperative chemoradiotherapy for cerebral glioblastoma].

  Voprosy onkologii 20080101

• The prince and the pauper. A tale of anticancer targeted agents.

  Molecular cancer 20080101

• Antitumor effects of desmopressin in combination with chemotherapeutic agents in a mouse model of breast cancer.

  Anticancer research 20080101

• [Clinical features and combined treatment of the central nervous system in Hodgkin's disease].

  Voprosy onkologii 20080101

• Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells.

  Journal of translational medicine 20080101

• [(18)F]Fluoroethyltyrosine- positron emission tomography-guided radiotherapy for high-grade glioma.

  Radiation oncology (London, England) 20080101

• Crossing borders: surgically mediated drug delivery techniques.

  Clinical neurosurgery 20080101

• Reinduction of bevacizumab in combination with pegylated liposomal Doxorubicin in a patient with recurrent glioblastoma multiforme who progressed on bevacizumab/irinotecan.

  Journal of oncology 20080101

• [Evaluation of selected endocrine complications in patients treated with auto- and allo-haematopoietic stem cell transplantation].

  Medycyna wieku rozwojowego 20080101

• Strategies for enhanced drug delivery to the central nervous system.

  Indian journal of pharmaceutical sciences 20080101

• A Single Institution's Experience with Bevacizumab in Combination with Cytotoxic Chemotherapy in Progressive Malignant Glioma.

  Clinical medicine. Oncology 20080101

• Differential sensitivity of malignant glioma cells to methylating and chloroethylating anticancer drugs: p53 determines the switch by regulating xpc, ddb2, and DNA double-strand breaks.

  Cancer research 20071215

• Refractory multiple myeloma treated with homoharringtonine: report of two cases.

  Annals of hematology 20071201

• Generation and functional characterization of mice with a disrupted glutathione S-transferase, theta 1 gene.

  Drug metabolism and disposition: the biological fate of chemicals 20071201

• Phenol-induced in vivo oxidative stress in skin: evidence for enhanced free radical generation, thiol oxidation, and antioxidant depletion.

  Chemical research in toxicology 20071201

• Management of glioblastoma.

  Expert opinion on pharmacotherapy 20071201

• [Chlormethine (Caryolysine), carmustine (Bicnu)].

  Annales de dermatologie et de venereologie 20071201

• Management of patients with newly diagnosed malignant primary brain tumors with a focus on the evolving role of temozolomide.

  Therapeutics and clinical risk management 20071201

• Cisplatin, gemcitabine, and treosulfan in relapsed stage IV cutaneous malignant melanoma patients.

  British journal of cancer 20071119

• Tamoxifen accelerates proteasomal degradation of O6-methylguanine DNA methyltransferase in human cancer cells.

  International journal of cancer 20071115

• Resorbable polymer microchips releasing BCNU inhibit tumor growth in the rat 9L flank model.

  Journal of controlled release : official journal of the Controlled Release Society 20071106

• Outcome of children treated with preradiation chemotherapy for a high-grade glioma: results of a French Society of Pediatric Oncology (SFOP) Pilot Study.

  Pediatric blood & cancer 20071101

• Frequency, severity and risk factors for oral mucositis after BEAM conditioning and autologous peripheral blood stem cell transplantation: a single center analysis and review of the literature.

  Leukemia & lymphoma 20071101

• The effectiveness and cost-effectiveness of carmustine implants and temozolomide for the treatment of newly diagnosed high-grade glioma: a systematic review and economic evaluation.

  Health technology assessment (Winchester, England) 20071101

• Inactivation of O(6)-alkylguanine-DNA alkyltransferase by folate esters of O(6)-benzyl-2'-deoxyguanosine and of O(6)-[4-(hydroxymethyl)benzyl]guanine.

  Journal of medicinal chemistry 20071018

• Primary refractory Hodgkin's lymphoma: outcome after high-dose chemotherapy and autologous SCT and impact of various prognostic factors on overall and event-free survival. A single institution result of 66 patients.

  Bone marrow transplantation 20071001

• Uptake and reduction of alpha-lipoic acid by human erythrocytes.

  Clinical biochemistry 20071001

• Transplantation tolerance: lessons from experimental rodent models.

  Transplant international : official journal of the European Society for Organ Transplantation 20071001

• Ultrasound-enhanced chemotherapy and gene delivery for glioma cells.

  Technology in cancer research & treatment 20071001

• Gliadel wafers in the treatment of malignant glioma: a systematic review.

  Current oncology (Toronto, Ont.) 20071001

• Autologous stem cell transplantation for chronic lymphocytic leukemia.

  Seminars in hematology 20071001

• Tumorigenesis of chemotherapeutic drug-resistant cancer stem-like cells in brain glioma.

  Stem cells and development 20071001

• Interstitial chemotherapy with biodegradable BCNU (Gliadel) wafers in the treatment of malignant gliomas.

  Therapeutics and clinical risk management 20071001

• Stable differentiation and clonality of murine long-term hematopoiesis after extended reduced-intensity selection for MGMT P140K transgene expression.

  Blood 20070915

• [What type of adjuvant chemotherapy should be proposed for the initial treatment of glioblastoma?].

  Presse medicale (Paris, France : 1983) 20070901

• Zebrafish as a model system to screen radiation modifiers.

  Current genomics 20070901

• Diagnosis and management of primary intraocular lymphoma: an update.

  Clinical ophthalmology (Auckland, N.Z.) 20070901

• O6-benzylguanine and BCNU in multiple myeloma: a phase II trial.

  Cancer chemotherapy and pharmacology 20070801

• Spontaneous pregnancy and normal delivery after repeated autologous bone marrow transplantation and GnRH agonist treatment.

  Human reproduction (Oxford, England) 20070801

• Selective cell death of oncogenic Akt-transduced brain cancer cells by etoposide through reactive oxygen species mediated damage.

  Molecular cancer therapeutics 20070801

• [Complete remission of relapsed mixed cellularity Hodgkin's disease treated with rituximab].

  Deutsche medizinische Wochenschrift (1946) 20070801

• Mycosis fungoides.

  Dermatology nursing 20070801

• The phosphoinositide 3-kinase pathway in human cancer: genetic alterations and therapeutic implications.

  Current genomics 20070801

• Neuroprotective effects of melatonin upon the offspring cerebellar cortex in the rat model of BCNU-induced cortical dysplasia.

  Brain research 20070730

• Hypoxic remodelling of Ca2+signalling in SH-SY5Y cells: influence of glutathione.

  Neuroreport 20070702

• The interaction of chromium (VI) with macrophages: depletion of glutathione and inhibition of glutathione reductase.

  Toxicology 20070701

• New chemotherapy options for the treatment of malignant gliomas.

  Anti-cancer drugs 20070701

• Treatment of single brain metastasis with resection, intracavity carmustine polymer wafers, and radiation therapy is safe and provides excellent local control.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20070615

• Characterization of DNA reactive and non-DNA reactive anticancer drugs by gene expression profiling.

  Mutation research 20070601

• Glutaredoxin mediates Akt and eNOS activation by flow in a glutathione reductase-dependent manner.

  Arteriosclerosis, thrombosis, and vascular biology 20070601

• Canadian recommendations for the treatment of glioblastoma multiforme.

  Current oncology (Toronto, Ont.) 20070601

• Microphthalmos associated with Dartmouth combination chemotherapy in pregnancy: a case report.

  The Journal of reproductive medicine 20070601

• Reappraisal of the use of procarbazine in the treatment of lymphomas and brain tumors.

  Therapeutics and clinical risk management 20070601

• An overview of the clinical use of ondansetron in preschool age children.

  Therapeutics and clinical risk management 20070601

• [Changes of expression of cation-chloride cotransporter genes in hippocampus of cortical dysplasia: experiment with rat].

  Zhonghua yi xue za zhi 20070522

• Role of O6-methylguanine-DNA methyltransferase in protecting from alkylating agent-induced toxicity and mutations in mice.

  Carcinogenesis 20070501

• Single nucleotide polymorphisms and expression of ERCC1 and ERCC2 vis-à-vis chemotherapy drug cytotoxicity in human glioma.

  Journal of neuro-oncology 20070501

• Interstitial chemotherapy for malignant gliomas: the Johns Hopkins experience.

  Journal of neuro-oncology 20070501

• The Fanconi anemia (FA) pathway confers glioma resistance to DNA alkylating agents.

  Journal of molecular medicine (Berlin, Germany) 20070501

• A second autologous transplant may be efficacious in selected patients with Hodgkin's lymphoma relapsing after a previous autograft.

  Leukemia & lymphoma 20070501

• Long-term outcomes after reduced-intensity conditioning allogeneic stem cell transplantation for low-grade lymphoma: a survey by the French Society of Bone Marrow Graft Transplantation and Cellular Therapy (SFGM-TC).

  Haematologica 20070501

• Adjuvant therapy in glioblastomas: false steps and real advances.

  Expert review of anticancer therapy 20070501

• In vivo selection and chemoprotection after drug resistance gene therapy in a nonmyeloablative allogeneic transplantation setting in dogs.

  Human gene therapy 20070501

• Transglutaminase 2 inhibitor, KCC009, disrupts fibronectin assembly in the extracellular matrix and sensitizes orthotopic glioblastomas to chemotherapy.

  Oncogene 20070419

• The 1p-encoded protein stathmin and resistance of malignant gliomas to nitrosoureas.

  Journal of the National Cancer Institute 20070418

• Does high-dose carmustine increase overall survival in supratentorial high-grade malignant glioma? An EBMT retrospective study.

  International journal of cancer 20070415

• Zinc stimulates the production of toxic reactive oxygen species (ROS) and inhibits glutathione reductase in astrocytes.

  Free radical biology & medicine 20070415

• Autologous peripheral blood stem cell transplantation in multiple myeloma using oral versus I.V. melphalan.

  Annals of hematology 20070401

• Efficacy and tolerability of currently available therapies for the mycosis fungoides and Sezary syndrome variants of cutaneous T-cell lymphoma.

  Cancer treatment reviews 20070401

• Yttrium-90-ibritumomab tiuxetan (Zevalin) combined with high-dose BEAM chemotherapy and autologous stem cell transplantation for chemo-refractory aggressive non-Hodgkin's lymphoma.

  Experimental hematology 20070401

• Cellular and functional characterization of immunoresistant human glioma cell clones selected with alloreactive cytotoxic T lymphocytes reveals their up-regulated synthesis of biologically active TGF-beta.

  Journal of immunotherapy (Hagerstown, Md. : 1997) 20070401

• [Transdermal fentanyl in treating severe painful mucositis caused by autologous hematopoietic stem cell transplantation].

  Ai zheng = Aizheng = Chinese journal of cancer 20070401

• Dynamics of chemosensitivity and chromosomal instability in recurrent glioblastoma.

  British journal of cancer 20070326

• Monitoring the effects of BCNU chemotherapy Wafers (Gliadel) in glioblastoma multiforme with proton magnetic resonance spectroscopic imaging at 3.0 Tesla.

  Journal of neuro-oncology 20070301

• Higher glioblastoma tumour burden reduces efficacy of chemotherapeutic agents: in vitro evidence.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20070301

• Fatal outcome related to carmustine implants in glioblastoma multiforme.

  Acta neurochirurgica 20070301

• Autologous stem cell transplantation after complete remission and first consolidation in acute myeloid leukemia patients aged 61-70 years: results of the prospective EORTC-GIMEMA AML-13 study.

  Haematologica 20070301

• Palifermin and palmar-plantar erythrodysesthesia.

  British journal of haematology 20070301

• High-dose chemotherapy using BEAM without autologous rescue followed by reduced-intensity conditioning allogeneic stem-cell transplantation for refractory or relapsing lymphomas: a comparison of delayed versus immediate transplantation.

  Bone marrow transplantation 20070301

• Tandem high-dose chemotherapy and autologous stem cell transplantation in refractory/relapsed Hodgkin's lymphoma: a monocenter prospective study.

  American journal of hematology 20070201

• Phase I trial of polifeprosan 20 with carmustine implant plus continuous infusion of intravenous O6-benzylguanine in adults with recurrent malignant glioma: new approaches to brain tumor therapy CNS consortium trial.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070201

• Fatal leukoencephalopathy after reduced-intensity allogeneic stem cell transplantation.

  Onkologie 20070201

• Imaging response in malignant glioma, RTOG 90-06.

  American journal of clinical oncology 20070201

• In vivo imaging in a murine model of glioblastoma.

  Neurosurgery 20070201

• Factors influencing engraftment in autologous peripheral hematopoetic stem cell transplantation (PBSCT).

  Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20070201

• Dexa-BEAM as salvage therapy in patients with primary refractory aggressive non-Hodgkin lymphoma.

  Leukemia & lymphoma 20070201

• Dang-Gui Buxue Tang protects against oxidant injury by enhancing cellular glutathione in H9c2 cells: role of glutathione synthesis and regeneration.

  Planta medica 20070201

• Small cell carcinoma of the nasopharynx.

  Acta oto-laryngologica 20070201

• [What is your diagnosis? Neutropenic colitis (neutropenic typhlitis)].

  Praxis 20070124

• Alleviation of 1,N6-ethanoadenine genotoxicity by the Escherichia coli adaptive response protein AlkB.

  Proceedings of the National Academy of Sciences of the United States of America 20070116

• A phase I/II study of lomustine and temozolomide in patients with cerebral metastases from malignant melanoma.

  British journal of cancer 20070115

• Levels and distribution of BCNU in GBM tumors following intratumoral injection of DTI-015 (BCNU-ethanol).

  Neuro-oncology 20070101

• Initial chemotherapy with mitoxantrone, chlorambucil, prednisone impairs the collection of stem cells in patients with indolent lymphomas--results of a randomized comparison by the German Low-Grade Lymphoma Study Group.

  Annals of oncology : official journal of the European Society for Medical Oncology 20070101

• Combination chemotherapy followed by autologous stem cell transplant for enteropathy-associated T cell lymphoma.

  British journal of haematology 20070101

• Enantioselectivity of thalidomide serum and tissue concentrations in a rat glioma model and effects of combination treatment with cisplatin and BCNU.

  The Journal of pharmacy and pharmacology 20070101

• A dominant-negative form of the major human abasic endonuclease enhances cellular sensitivity to laboratory and clinical DNA-damaging agents.

  Molecular cancer research : MCR 20070101

• High-dose therapy and autologous stem cell transplantation for Hodgkin's lymphoma in relapse or failure after initial chemotherapy : results of the Centre National de Greffe de Moelle Osseuse de Tunis.

  La Tunisie medicale 20070101

• Fibrillary glomerulonephritis with small fibrils in a patient with the antiphospholipid antibody syndrome successfully treated with immunosuppressive therapy.

  BMC nephrology 20070101

• BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease.

  International journal of medical sciences 20070101

• [Visual cortes--is it a concern?].

  Bulletin de la Societe belge d'ophtalmologie 20070101

• Radiotherapeutic alternatives for previously irradiated recurrent gliomas.

  BMC cancer 20070101

• Spontaneous immune responses against glioma-associated antigens in a long term survivor with malignant glioma.

  Journal of translational medicine 20070101

• Valproic acid increases the in vitro effects of nitrosureas on human glioma cell lines.

  Oncology research 20070101

• Mitochondrial recycling of ascorbic acid as a mechanism for regenerating cellular ascorbate.

  BioFactors (Oxford, England) 20070101

• [Clinical significance of mustoforan in management of malignant glioma].

  Voprosy onkologii 20070101

• Trypanothione reductase: a viable chemotherapeutic target for antitrypanosomal and antileishmanial drug design.

  Drug target insights 20070101

• Targeted brain tumor treatment-current perspectives.

  Drug target insights 20070101

• Proton and sodium MRI assessment of emerging tumor chemotherapeutic resistance.

  NMR in biomedicine 20061201

• Drug compatibility with new polyolefin infusion solution containers.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20061201

• Proteomic analysis reveals higher demand for antioxidant protection in embryonic stem cell-derived smooth muscle cells.

  Proteomics 20061201

• Patient with resected anaplastic astrocytoma and an image suggestive of relapse.

  Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20061201

• [Local chemotherapy for brain tumors].

  Medizinische Monatsschrift fur Pharmazeuten 20061201

• Autologous stem cell transplantation for progressive multiple sclerosis: update of the European Group for Blood and Marrow Transplantation autoimmune diseases working party database.

  Multiple sclerosis (Houndmills, Basingstoke, England) 20061201

• New methods for direct delivery of chemotherapy for treating brain tumors.

  The Yale journal of biology and medicine 20061201

• Clinical outcomes after autologous haematopoietic stem cell transplantation in patients with progressive multiple sclerosis.

  Chinese medical journal 20061120

• Cotreatment with a novel phosphoinositide analogue inhibitor and carmustine enhances chemotherapeutic efficacy by attenuating AKT activity in gliomas.

  Cancer 20061115

• CXCR4 inhibition synergizes with cytotoxic chemotherapy in gliomas.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20061115

• Chemotherapy for primary central nervous system lymphoma.

  Neurosurgical focus 20061115

• Temozolomide 3 weeks on and 1 week off as first-line therapy for recurrent glioblastoma: phase II study from gruppo italiano cooperativo di neuro-oncologia (GICNO).

  British journal of cancer 20061106

• A phase II trial of O6-benzylguanine and carmustine in patients with advanced soft tissue sarcoma.

  Cancer chemotherapy and pharmacology 20061101

• Expression of glutathione S-transferase T1 (GSTT1) in human brain tumours.

  Histology and histopathology 20061101

• The natural compound n-butylidenephthalide derived from Angelica sinensis inhibits malignant brain tumor growth in vitro and in vivo.

  Journal of neurochemistry 20061101

• High dose chemotherapy and autologous stem cell transplantation in non-Hodgkin's lymphoma: an eight-year experience.

  Yonsei medical journal 20061031

• Phase II trial of radiotherapy after hyperbaric oxygenation with chemotherapy for high-grade gliomas.

  British journal of cancer 20061009

• The multikinase inhibitor midostaurin (PKC412A) lacks activity in metastatic melanoma: a phase IIA clinical and biologic study.

  British journal of cancer 20061009

• Interstitial docetaxel (taxotere), carmustine and combined interstitial therapy: a novel treatment for experimental malignant glioma.

  Journal of neuro-oncology 20061001

• Outpatient autologous hematopoietic stem cell transplantation for patients with relapsed follicular lymphoma.

  Annals of hematology 20061001

• Autologous peripheral blood stem cell transplantation for severe multiple sclerosis.

  International journal of hematology 20061001

• Inhibition of human glutathione transferases by multidrug resistance chemomodulators in vitro.

  Journal of enzyme inhibition and medicinal chemistry 20061001

• Discovery of antiglioma activity of biaryl 1,2,3,4-tetrahydroisoquinoline derivatives and conformationally flexible analogues.

  Journal of medicinal chemistry 20060921

• BCNU-loaded PEG-PLLA ultrafine fibers and their in vitro antitumor activity against Glioma C6 cells.

  Journal of controlled release : official journal of the Controlled Release Society 20060912

• Higher incidence of chemotherapy induced oral mucositis in females: a supplement of multivariate analysis to a randomized multicentre study.

  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20060901

• Long-term follow-up of patients with peripheral T-cell lymphomas treated up-front with high-dose chemotherapy followed by autologous stem cell transplantation.

  Leukemia 20060901

• Treatment options in relapsed or refractory Hodgkin disease patients: the mini-BEAM regimen does exist too.

  British journal of haematology 20060901

• Characterisation of a P140K mutant O6-methylguanine-DNA-methyltransferase (MGMT)-expressing transgenic mouse line with drug-selectable bone marrow.

  The journal of gene medicine 20060901

• High-dose chemotherapy with autologous stem cell transplantation as first-line therapy for primary CNS lymphoma in patients younger than 60 years: a multicenter phase II study of the GOELAMS group.

  Bone marrow transplantation 20060901

• Prolonged remission in a case of Richter's transformation of B-cell chronic lymphocytic leukaemia following adoptive immunotherapy.

  Bone marrow transplantation 20060901

• Genetic alterations associated with acquired temozolomide resistance in SNB-19, a human glioma cell line.

  Molecular cancer therapeutics 20060901

• Salvage chemotherapy in follicular non-Hodgkin's lymphoma: focus on tolerability.

  Clinical lymphoma & myeloma 20060901

• High-dose chemotherapy with autologous stem-cell transplantation and hyperfractionated radiotherapy as first-line treatment of primary CNS lymphoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060820

• Phase III trial of carmustine and cisplatin compared with carmustine alone and standard radiation therapy or accelerated radiation therapy in patients with glioblastoma multiforme: North Central Cancer Treatment Group 93-72-52 and Southwest Oncology Group 9503 Trials.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060820

• Hydrogen peroxide and redox modulation sensitize primary mouse hepatocytes to TNF-induced apoptosis.

  Free radical biology & medicine 20060815

• Dual agent chemoprotection by retroviral co-expression of either MDR1 or MRP1 with the P140K mutant of O6-methylguanine-DNA-methyl transferase.

  The journal of gene medicine 20060801

• A phase II trial of accelerated radiotherapy using weekly stereotactic conformal boost for supratentorial glioblastoma multiforme: RTOG 0023.

  International journal of radiation oncology, biology, physics 20060801

• Cardiac effects within 3 months of BEAC high-dose therapy in non-Hodgkin's lymphoma patients undergoing autologous stem cell transplantation.

  European journal of haematology 20060801

• Narrowband UVB phototherapy for early-stage mycosis fungoides: evaluation of clinical and histopathological changes.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20060801

• In vitro drug response and molecular markers associated with drug resistance in malignant gliomas.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20060801

• Hypoxia-inducible factor-1 inhibition in combination with temozolomide treatment exhibits robust antitumor efficacy in vivo.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20060801

• Mitotic arrest, apoptosis, and sensitization to chemotherapy of melanomas by methionine deprivation stress.

  Molecular cancer research : MCR 20060801

• Efficacy of single-dose pegfilgrastim after chemotherapy for the mobilization of autologous peripheral blood stem cells in patients with malignant lymphoma or multiple myeloma.

  Transfusion 20060801

• Toxicity of high dose BCNU: how much is too much?

  Leukemia & lymphoma 20060801

• Morbidity and transplant-related mortality of CBV and BEAM preparative regimens for patients with lymphoid malignancies undergoing autologous stem-cell transplantation.

  Leukemia & lymphoma 20060801

• A pilot clinical study of Delta9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme.

  British journal of cancer 20060717

• The role of haemoglobin level in predicting the response to first-line chemotherapy in advanced colorectal cancer patients.

  British journal of cancer 20060703

• SarCNU in recurrent or metastatic colorectal cancer: a phase II study of the National Cancer Institute of Canada Clinical Trials Group.

  Investigational new drugs 20060701

• Predicting and monitoring response to chemotherapy by 1,3-bis(2-chloroethyl)-1-nitrosourea in subcutaneously implanted 9L glioma using the apparent diffusion coefficient of water and 23Na MRI.

  Journal of magnetic resonance imaging : JMRI 20060701

• Stimulation of the alveolar macrophage respiratory burst by ADP causes selective glutathionylation of protein tyrosine phosphatase 1B.

  Free radical biology & medicine 20060701

• High-dose carmustine, etoposide, and cyclophosphamide followed by allogeneic hematopoietic cell transplantation for non-Hodgkin lymphoma.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20060701

• Role of p16 and p14ARF in radio- and chemosensitivity of malignant gliomas.

  Oncology reports 20060701

• Cellular disulfide-reducing capacity: an integrated measure of cell redox capacity.

  Biochemical and biophysical research communications 20060616

• Upfront double high-dose chemotherapy with DICEP followed by BEAM and autologous stem cell transplantation for poor-prognosis aggressive non-Hodgkin lymphoma.

  Blood 20060615

• Cyclin D1 degradation enhances endothelial cell survival upon oxidative stress.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060601

• A prospective PET study of patients with glioblastoma multiforme.

  Acta neurologica Scandinavica 20060601

• Inactivation of O6-alkylguanine DNA alkyltransferase as a means to enhance chemotherapy.

  Cancer treatment reviews 20060601

• Palifermin for oral mucositis in the high-dose chemotherapy and stem cell transplant setting: the Royal Adelaide Hospital Cancer Centre experience.

  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20060601

• High exposures to bioactivated cyclophosphamide are related to the occurrence of veno-occlusive disease of the liver following high-dose chemotherapy.

  British journal of cancer 20060508

• Ototoxicity of cisplatin plus standard radiation therapy vs. accelerated radiation therapy in glioblastoma patients.

  Journal of neuro-oncology 20060501

• Response to chemotherapy of a radiation-induced glioblastoma multiforme.

  Journal of neuro-oncology 20060501

• In vivo effects of myeloablative alkylator therapy on survival and differentiation of MGMTP140K-transduced human G-CSF-mobilized peripheral blood cells.

  Molecular therapy : the journal of the American Society of Gene Therapy 20060501

• High-dose chemotherapy and autologous peripheral blood stem cell transplantation for primary breast cancer refractory to neoadjuvant chemotherapy.

  Bone marrow transplantation 20060501

• Complete response in multiple myeloma: clinical trial E9486, an Eastern Cooperative Oncology Group study not involving stem cell transplantation.

  Cancer 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Effect of chemotherapy with alkylating agents on the yield of CD34+ cells in patients with multiple myeloma. Results of the Spanish Myeloma Group (GEM) Study.

  Haematologica 20060501

• Minimal residual disease in hypopigmented mycosis fungoides.

  Journal of the American Academy of Dermatology 20060501

• Dynamic imaging of emerging resistance during cancer therapy.

  Cancer research 20060501

• Randomised phase III study of R-ICE versus R-DHAP in relapsed patients with CD20 diffuse large B-cell lymphoma (DLBCL) followed by high-dose therapy and a second randomisation to maintenance treatment with rituximab or not: an update of the CORAL study.

  Annals of oncology : official journal of the European Society for Medical Oncology 20060501

• Successful autologous hematopoietic stem cell transplantations for severe multiple sclerosis with fludarabine and cyclophosphamide conditioning.

  International journal of hematology 20060501

• Causes and outcomes of spontaneous pneumothoraces in solid tumor cancer patients: an update for the medical oncologist.

  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20060501

• The novel antioxidant 3-O-caffeoyl-1-methylquinic acid induces Nrf2-dependent phase II detoxifying genes and alters intracellular glutathione redox.

  Free radical biology & medicine 20060415

• The IL-4 and IL-13 pseudomonas exotoxins: new hope for brain tumor therapy.

  Neurosurgical focus 20060415

• Management of malignant glioma: steady progress with multimodal approaches.

  Neurosurgical focus 20060415

• Cardiac toxicity of trastuzumab in metastatic breast cancer patients previously treated with high-dose chemotherapy: a retrospective study.

  British journal of cancer 20060410

• Safety and efficacy of a novel cannabinoid chemotherapeutic, KM-233, for the treatment of high-grade glioma.

  Journal of neuro-oncology 20060401

• Sodium and proton diffusion MRI as biomarkers for early therapeutic response in subcutaneous tumors.

  Magnetic resonance imaging 20060401

• Circulating levels and clinical significance of soluble CD86 in myeloma patients.

  British journal of haematology 20060401

• The functional diffusion map: an imaging biomarker for the early prediction of cancer treatment outcome.

  Neoplasia (New York, N.Y.) 20060401

• Permeability of 13 different gloves to 13 cytotoxic agents under controlled dynamic conditions.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20060315

• Summaries for patients. Adding chloroquine to conventional chemotherapy and radiotherapy for glioblastoma multiforme.

  Annals of internal medicine 20060307

• Adding chloroquine to conventional treatment for glioblastoma multiforme: a randomized, double-blind, placebo-controlled trial.

  Annals of internal medicine 20060307

• Immune thrombocytopenia following successful treatment of cancer in children.

  Pediatric blood & cancer 20060301

• O(6)-methylguanine DNA-methyltransferase (MGMT) overexpression in melanoma cells induces resistance to nitrosoureas and temozolomide but sensitizes to mitomycin C.

  Toxicology and applied pharmacology 20060301

• Intracavitary chemotherapy (Gliadel) for recurrent esthesioneuroblastoma: case report and review of the literature.

  Journal of neuro-oncology 20060301

• Redox control of K+ channel remodeling in rat ventricle.

  Journal of molecular and cellular cardiology 20060301

• Efficacy of diverse high-dose regimens followed by autologous peripheral blood stem cell transplantation in consecutive multiple myeloma patients: a single-centre analysis over a 12-year period.

  Annals of hematology 20060301

• Acute depletion of reduced glutathione causes extensive carbonylation of rat brain proteins.

  Journal of neuroscience research 20060301

• Cancer therapy-associated CNS neuropathology: an update and review of the literature.

  Acta neuropathologica 20060301

• Gliadel wafer in initial surgery for malignant glioma: long-term follow-up of a multicenter controlled trial.

  Acta neurochirurgica 20060301

• Inhibition of vascular endothelial growth factor (VEGF)-A causes a paradoxical increase in tumor blood flow and up-regulation of VEGF-D.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20060301

• [Management of malignant gliomas diagnosed during pregnancy].

  Revue neurologique 20060301

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20060301

• [Sensitivity profile of a panel of cell lines designed for the evaluation of in vitro cytotoxicity].

  Biomedica : revista del Instituto Nacional de Salud 20060301

• Standard chemotherapy compared with high-dose chemoradiotherapy for multiple myeloma: final results of phase III US Intergroup Trial S9321.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060220

• Involvement of NF-kappaB and glutathione in cytotoxic effects of nitric oxide and taxol on human leukemia cells.

  Leukemia research 20060201

• DNA repair enzyme, O6-methylguanine DNA methyltransferase, modulates cytotoxicity of camptothecin-derived topoisomerase I inhibitors.

  The Journal of pharmacology and experimental therapeutics 20060201

• Successful autologous peripheral blood stem cell harvest and transplant in a patient with cold agglutinins.

  Bone marrow transplantation 20060201

• Results of a phase I/II trial adding carmustine (300 mg/m2) to melphalan (200 mg/m2) in multiple myeloma patients undergoing autologous stem cell transplantation.

  Leukemia 20060201

• O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells.

  Journal of neurochemistry 20060201

• Comparison of peripheral blood progenitor cell yield from standard chemotherapy used in the treatment of lymphoid malignancies and high-dose cyclophosphamide: a retrospective review of 141 patients.

  Transfusion 20060201

• Consolidation with high-dose combination alkylating agents with bone marrow transplantation significantly improves disease-free survival in hormone-insensitive metastatic breast cancer in complete remission compared with intensive standard-dose chemotherapy alone.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20060201

• Glioblastoma--more questions than answers?

  Nature clinical practice. Oncology 20060201

• Clinical experience: practical management of five patients with cutaneous T-cell lymphoma (CTCL)-related symptoms.

  Seminars in oncology 20060201

• Similar response rates and superior early progression-free survival with gemcitabine, dexamethasone, and cisplatin salvage therapy compared with carmustine, etoposide, cytarabine, and melphalan salvage therapy prior to autologous stem cell transplantation for recurrent or refractory Hodgkin lymphoma.

  Cancer 20060115

• Tumor necrosis factor-alpha-induced protein 3 as a putative regulator of nuclear factor-kappaB-mediated resistance to O6-alkylating agents in human glioblastomas.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060110

• Trial of amifostine in autologous stem cell transplant.

  Bone marrow transplantation 20060101

• Prophylaxis of central venous catheter-related thrombosis with minidose warfarin in patients treated with high-dose chemotherapy and peripheral-blood stem-cell transplantation: retrospective analysis of 228 cancer patients.

  American journal of hematology 20060101

• Over-representation of specific regions of chromosome 22 in cells from human glioma correlate with resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea.

  BMC cancer 20060101

• Differential competitive resistance to methylating versus chloroethylating agents among five O6-alkylguanine DNA alkyltransferases in human hematopoietic cells.

  Molecular cancer therapeutics 20060101

• Multicistronic lentiviral vectors containing the FMDV 2A cleavage factor demonstrate robust expression of encoded genes at limiting MOI.

  Virology journal 20060101

• An unusual cause of alveolar hemorrhage post hematopoietic stem cell transplantation: a case report.

  BMC cancer 20060101

• Solitary pulmonary metastasis from primary melanoma of the oesophagus 5 years after resection of the primary tumor.

  World journal of surgical oncology 20060101

• Intraprostatic injection of botulinum toxin type-A relieves bladder outlet obstruction in human and induces prostate apoptosis in dogs.

  BMC urology 20060101

• Treatments for astrocytic tumors in children: current and emerging strategies.

  Paediatric drugs 20060101

• Anticancer activity of extracts derived from the mature roots of Scutellaria baicalensis on human malignant brain tumor cells.

  BMC complementary and alternative medicine 20060101

• Induction of cell cycle changes and modulation of apoptogenic/anti-apoptotic and extracellular signaling regulatory protein expression by water extracts of I'm-Yunity (PSP).

  BMC complementary and alternative medicine 20060101

• Glioblastoma multiforme with oligodendroglial component (GBMO): favorable outcome after post-operative radiotherapy and chemotherapy with nimustine (ACNU) and teniposide (VM26).

  BMC cancer 20060101

• Primary brain T-cell lymphoma after kidney transplantation: a case report.

  Surgical neurology 20060101

• Schisandrin B-induced increase in cellular glutathione level and protection against oxidant injury are mediated by the enhancement of glutathione synthesis and regeneration in AML12 and H9c2 cells.

  BioFactors (Oxford, England) 20060101

• CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivo.

  Journal of biology 20060101

• The long term effects of chemotherapy on the central nervous system.

  Journal of biology 20060101

• Treatment of mycosis fungoides: overview.

  Journal of cutaneous medicine and surgery 20060101

• [Boron neutron capture therapy applied to undifferentiated thyroid carcinoma].

  Medicina 20060101

• Prooxidant cytotoxicity of chromate in mammalian cells: the opposite roles of DT-diaphorase and glutathione reductase.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20060101

• Bortezomib: the evidence of its clinical impact in multiple myeloma.

  Core evidence 20060101

• Involvement of the immune response in the cure of metastatic murine CT-26 colon carcinoma by low electric field-enhanced chemotherapy.

  International journal of cancer 20051210

• Phase II trial of SarCNU in malignant glioma: unexpected pulmonary toxicity with a novel nitrosourea: a phase II trial of the national cancer institute of canada clinical trials group.

  Investigational new drugs 20051201

• High-dose therapy intensification compared with continued standard chemotherapy in multiple myeloma patients responding to the initial chemotherapy: long-term results from a prospective randomized trial from the Spanish cooperative group PETHEMA.

  Blood 20051201

• Role of O6-alkylguanine-DNA alkyltransferase in protecting against 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-induced long-term toxicities.

  The Journal of pharmacology and experimental therapeutics 20051201

• Very acute cardiac toxicity during BEAC chemotherapy in non-Hodgkin's lymphoma patients undergoing autologous stem cell transplantation.

  Bone marrow transplantation 20051201

• [Treatment for malignant glioma].

  No to shinkei = Brain and nerve 20051201

• Hematopoietic stem cell transduction and amplification in large animal models.

  Human gene therapy 20051201

• Interstitial transfer factor as adjuvant immunotherapy for experimental glioma.

  Journal of experimental & clinical cancer research : CR 20051201

• Sensitization of human carcinoma cells to alkylating agents by small interfering RNA suppression of 3-alkyladenine-DNA glycosylase.

  Cancer research 20051115

• O6-(4-bromothenyl)guanine reverses temozolomide resistance in human breast tumour MCF-7 cells and xenografts.

  British journal of cancer 20051114

• Occurrence of multiple myeloma 13 years after Hodgkin's disease: chance or consequence?

  Annals of hematology 20051101

• A novel thiol oxidation-based mechanism for adriamycin-induced cell injury in human macrophages.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051101

• Chemotherapy in brain metastases.

  Neurosurgery 20051101

• Current treatment paradigms for the management of patients with brain metastases.

  Neurosurgery 20051101

• Intra-arterial chemotherapy of primary brain tumors.

  Current treatment options in oncology 20051101

• Role of O6-alkylguanine-DNA alkyltransferase in the cytotoxic activity of cloretazine.

  Molecular cancer therapeutics 20051101

• Phase II trial of the O6-alkylguanine DNA alkyltransferase inhibitor O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea in advanced melanoma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20051101

• Quality of life among patients with Stage II and III breast carcinoma randomized to receive high-dose chemotherapy with autologous bone marrow support or intermediate-dose chemotherapy: results from Cancer and Leukemia Group B 9066.

  Cancer 20051015

• Apurinic/apyrimidinic endonuclease activity is associated with response to radiation and chemotherapy in medulloblastoma and primitive neuroectodermal tumors.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20051015

• 2-Chloroethyl-3-sarcosinamide-1-nitrosourea (SarCNU) exhibits p53-dependent and -independent antiproliferative activity in human nasopharyngeal carcinoma cells in vitro and in vivo.

  International journal of oncology 20051001

• Ifosfamide, epirubicin, etoposide (IEV) and autologous peripheral blood progenitor cell transplant: a feasible and effective salvage treatment for lymphoid malignancies.

  Oncology reports 20051001

• First-line autologous stem cell transplantation in primary CNS lymphoma.

  European journal of haematology 20051001

• Augmented high-dose regimen of cyclophosphamide, carmustine, and etoposide with autologous hematopoietic stem cell transplantation for relapsed and refractory aggressive non-Hodgkin's lymphoma.

  Leukemia & lymphoma 20051001

• Development of a large-scale chemogenomics database to improve drug candidate selection and to understand mechanisms of chemical toxicity and action.

  Journal of biotechnology 20050929

• Recent clinical studies of the immunomodulatory drug (IMiD) lenalidomide.

  British journal of cancer 20050919

• Quantitative structure-activity relationships in prooxidant cytotoxicity of polyphenols: role of potential of phenoxyl radical/phenol redox couple.

  Archives of biochemistry and biophysics 20050915

• Enhancement of the stability of BCNU using self-emulsifying drug delivery systems (SEDDS) and in vitro antitumor activity of self-emulsified BCNU-loaded PLGA wafer.

  International journal of pharmaceutics 20050914

• Dose finding and O6-alkylguanine-DNA alkyltransferase study of cisplatin combined with temozolomide in paediatric solid malignancies.

  British journal of cancer 20050905

• SarCNU-induced G2/M arrest in hepatoma cells is mediated by a p53-independent phosphorylation of cdc-2 at Tyr15.

  Journal of cellular physiology 20050901

• Inhibition of thioredoxin reductase but not of glutathione reductase by the major classes of alkylating and platinum-containing anticancer compounds.

  Free radical biology & medicine 20050901

• Associations between drug metabolism genotype, chemotherapy pharmacokinetics, and overall survival in patients with breast cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050901

• The American Society for Therapeutic Radiology and Oncology (ASTRO) evidence-based review of the role of radiosurgery for malignant glioma.

  International journal of radiation oncology, biology, physics 20050901

• Tissue transglutaminase 2 inhibition promotes cell death and chemosensitivity in glioblastomas.

  Molecular cancer therapeutics 20050901

• Retinamide-induced apoptosis in glioblastomas is associated with down-regulation of Bcl-xL and Bcl-2 proteins.

  Journal of neuro-oncology 20050901

• Inactivation of p53 sensitizes astrocytic glioma cells to BCNU and temozolomide, but not cisplatin.

  Journal of neuro-oncology 20050901

• Local treatment of malignant brain tumors using implantable chemotherapeutic polymers.

  Journal of the National Comprehensive Cancer Network : JNCCN 20050901

• Pharmaceutical-mediated inactivation of p53 sensitizes U87MG glioma cells to BCNU and temozolomide.

  International journal of cancer 20050820

• In vivo delivery of BCNU from a MEMS device to a tumor model.

  Journal of controlled release : official journal of the Controlled Release Society 20050818

• 2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino)- phenylcarbamoylsulfanyl]propionic acid and its derivatives as a novel class of glutathione reductase inhibitors.

  Journal of medicinal chemistry 20050811

• Autologous tandem transplantation in patients with primary progressive or relapsed/refractory lymphoma.

  Annals of hematology 20050801

• Biphasic lindane-induced oxidation of glutathione and inhibition of gap junctions in myometrial cells.

  Toxicological sciences : an official journal of the Society of Toxicology 20050801

• High-dose sequential chemotherapy followed by autologous stem cell transplantation in relapsed and refractory aggressive non-Hodgkin's lymphoma: results of a multicenter phase II study.

  Annals of oncology : official journal of the European Society for Medical Oncology 20050801

• The influence of ATP on poly(ADP-ribose) metabolism.

  International journal of molecular medicine 20050801

• Primary brain tumors treated with steroids and radiotherapy: low CD4 counts and risk of infection.

  International journal of radiation oncology, biology, physics 20050801

• Research on the anti-tumour effect of steroid lactam alkylator (NSC-294859) in comparison with conventional chemotherapeutics in malignant melanoma.

  Melanoma research 20050801

• Chemoembolization of the hepatic artery with BCNU for metastatic uveal melanoma: results of a phase II study.

  Melanoma research 20050801

• Successful bone marrow transplantation for life threatening xanthogranuloma disseminatum in neurofibromatosis type-1.

  Pediatric transplantation 20050801

• Prognostic significance of O6-methylguanine-DNA methyltransferase determined by promoter hypermethylation and immunohistochemical expression in anaplastic gliomas.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050715

• Long-term results of autologous stem cell transplantation for Hodgkin's disease (HD) and low-/intermediate-grade B non-Hodgkin's lymphoma (NHL): a report from the Austrian Stem Cell Transplantation Registry (ASCTR).

  Annals of hematology 20050701

• The comparative effects of povidone-iodine and normal saline mouthwashes on oral mucositis in patients after high-dose chemotherapy and APBSCT--results of a randomized multicentre study.

  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20050701

• Temozolomide in combination with BCNU before and after radiotherapy in patients with inoperable newly diagnosed glioblastoma multiforme.

  Annals of oncology : official journal of the European Society for Medical Oncology 20050701

• BAVC regimen and autologous bone marrow transplantation for APL patients in second molecular remission: updated results.

  Bone marrow transplantation 20050701

• Gene expression profile induced by BCNU in human glioma cell lines with differential MGMT expression.

  Journal of neuro-oncology 20050701

• Intratumoral injection of BCNU in ethanol (DTI-015) results in enhanced delivery to tumor--a pharmacokinetic study.

  Journal of neuro-oncology 20050701

• Mini-BEAM and autologous hematopoietic stem-cell transplant for treatment of post-transplant lymphoproliferative disorders.

  American journal of hematology 20050701

• A phase Ib clinical trial of PV701, a milk-derived protein extract, for the prevention and treatment of oral mucositis in patients undergoing high-dose BEAM chemotherapy.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20050701

• The role of interferon-alpha in a successful murine tumor therapy.

  Experimental biology and medicine (Maywood, N.J.) 20050701

• Treatment of brain tumors.

  The New England journal of medicine 20050602

• Late mortality in survivors of autologous hematopoietic-cell transplantation: report from the Bone Marrow Transplant Survivor Study.

  Blood 20050601

• Impact of three courses of intensified CHOP prior to high-dose sequential therapy followed by autologous stem-cell transplantation as first-line treatment in poor-risk, aggressive non-hodgkin's lymphoma: comparative analysis of Dutch-Belgian Hemato-Oncology Cooperative Group Studies 27 and 40.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050601

• In regard to Dr. Souhami et al. (Int J Radiat Oncol Biol Phys 2004;60:853-860).

  International journal of radiation oncology, biology, physics 20050601

• Evaluation of the effect of age on treatment-related mortality and relapse in patients with high-risk primary breast cancer receiving high-dose chemotherapy.

  American journal of clinical oncology 20050601

• Long-term follow up of high-dose chemotherapy with autologous stem cell rescue in adults with Ewing tumor.

  American journal of clinical oncology 20050601

• NGF rescues DRG neurons in vitro from oxidative damage produced by hemodialyzers.

  Neurotoxicology 20050601

• Prognostic value of the age-adjusted International Prognostic Index in chemosensitive recurrent or refractory non-Hodgkin's lymphomas treated with high-dose BEAM therapy and autologous stem cell transplantation.

  Leukemia & lymphoma 20050601

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20050601

• Differential inhibition of cellular glutathione reductase activity by isocyanates generated from the antitumor prodrugs Cloretazine and BCNU.

  Biochemical pharmacology 20050515

• Cylindrospermopsin genotoxicity and cytotoxicity: role of cytochrome P-450 and oxidative stress.

  Journal of toxicology and environmental health. Part A 20050514

• HMG CoA reductase inhibitors (statins) to treat Epstein-Barr virus-driven lymphoma.

  British journal of cancer 20050509

• Lack of survival benefit after stereotactic radiosurgery boost for glioblastoma multiforme: randomized comparison of stereotactic radiosurgery followed by conventional radiotherapy with carmustine to conventional radiotherapy with carmustine for patients with glioblastoma multiforme: report of radiation therapy oncology group 93-05 protocol: in regard to Souhami et al. (Int J Radiat Oncol Biol Phys 2004;60:853-860).

  International journal of radiation oncology, biology, physics 20050501

• A phase I trial of surgery, Gliadel wafer implantation, and immediate postoperative carboplatin in combination with radiation therapy for primary anaplastic astrocytoma or glioblastoma multiforme.

  Journal of neuro-oncology 20050501

• S-nitrosoglutathione and hypoxia-inducible factor-1 confer chemoresistance against carbamoylating cytotoxicity of BCNU in rat C6 glioma cells.

  Annals of the New York Academy of Sciences 20050501

• Gemcitabine, cisplatin and methylprednisolone (GEM-P) is an effective salvage regimen in patients with relapsed and refractory lymphoma.

  British journal of cancer 20050425

• Mitochondrial targeting of human O6-methylguanine DNA methyltransferase protects against cell killing by chemotherapeutic alkylating agents.

  Cancer research 20050415

• Prospective, randomized comparison of high-dose chemotherapy with stem-cell support versus intermediate-dose chemotherapy after surgery and adjuvant chemotherapy in women with high-risk primary breast cancer: a report of CALGB 9082, SWOG 9114, and NCIC MA-13.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050401

• Concurrent administration of high-dose rituximab before and after autologous stem-cell transplantation for relapsed aggressive B-cell non-Hodgkin's lymphomas.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050401

• Nephrotic syndrome in patients with peripheral blood stem cell transplant.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20050401

• O6-methylguanine-DNA methyltransferase, O6-benzylguanine, and resistance to clinical alkylators in pediatric primary brain tumor cell lines.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050401

• Chemistry and biology of dihydroisoxazole derivatives: selective inhibitors of human transglutaminase 2.

  Chemistry & biology 20050401

• Inactivated MGMT by O6-benzylguanine is associated with prolonged G2/M arrest in cancer cells treated with BCNU.

  Oncogene 20050324

• Autologous HSCT for severe progressive multiple sclerosis in a multicenter trial: impact on disease activity and quality of life.

  Blood 20050315

• An analysis of the utilisation of chemoprophylaxis against Pneumocystis jirovecii pneumonia in patients with malignancy receiving corticosteroid therapy at a cancer hospital.

  British journal of cancer 20050314

• Combined chemotherapy with carmustine, doxorubicin, etoposide, vincristine, and cyclophosphamide plus mitoxantrone, cytarabine and methotrexate with citrovorum factor for the treatment of aggressive non-Hodgkin lymphoma: a long-term follow-up study.

  Cancer 20050301

• Polyclonal chemoprotection against temozolomide in a large-animal model of drug resistance gene therapy.

  Blood 20050201

• CD8+ T-cell-depleted, matched unrelated donor, allogeneic bone marrow transplantation for advanced AML using busulfan-based preparative regimens.

  Bone marrow transplantation 20050201

• Enhanced cytotoxicity of bioreductive antitumor agents with dimethyl fumarate in human glioblastoma cells.

  Anti-cancer drugs 20050201

• Phase II trial of carmustine, cisplatin, and oral etoposide chemotherapy before radiotherapy for grade 3 astrocytoma (anaplastic astrocytoma): results of North Central Cancer Treatment Group trial 98-72-51.

  International journal of radiation oncology, biology, physics 20050201

• Lack of EGF receptor contributes to drug sensitivity of human germline cells.

  British journal of cancer 20050131

• Phase I trial of iodine-131 tositumomab with high-dose chemotherapy and autologous stem-cell transplantation for relapsed non-Hodgkin's lymphoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050120

• A non-crosslinking platinum-acridine hybrid agent shows enhanced cytotoxicity compared to clinical BCNU and cisplatin in glioblastoma cells.

  Bioorganic & medicinal chemistry letters 20050117

• Beta-glucuronidase-cleavable prodrugs of O6-benzylguanine and O6-benzyl-2'-deoxyguanosine.

  Journal of medicinal chemistry 20050113

• Differential effects of glucose deprivation on the cellular sensitivity towards photodynamic treatment-based production of reactive oxygen species and apoptosis-induction.

  FEBS letters 20050103

• Venous thromboembolism after high-dose chemotherapy in a patient with Hodgkin's lymphoma receiving the new oral contraceptive ethinylestradiol and drospirenone ('Yasmine').

  Bone marrow transplantation 20050101

• Evaluation of in vitro and in vivo antitumor activity of BCNU-loaded PLGA wafer against 9L gliosarcoma.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20050101

• Cologne high-dose sequential chemotherapy in relapsed and refractory Hodgkin lymphoma: results of a large multicenter study of the German Hodgkin Lymphoma Study Group (GHSG).

  Annals of oncology : official journal of the European Society for Medical Oncology 20050101

• High-dose carmustine, etoposide, and cisplatin for autologous stem cell transplantation with or without involved-field radiation for relapsed/refractory lymphoma: an effective regimen with low morbidity and mortality.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20050101

• Response to chemotherapy and treating institution predict survival in primary central nervous system lymphoma.

  British journal of haematology 20050101

• Effect of pre-transplant cumulative doses of chemotherapeutic drugs on early and long-term hematological recovery after autologous bone-marrow transplantation for lymphoma.

  Haematologica 20050101

• [Effect of photodynamic therapy combined with interstitial chemotherapy for gliomas].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050101

• Photodynamic treatment with fractionated light decreases production of reactive oxygen species and cytotoxicity in vitro via regeneration of glutathione.

  Photochemistry and photobiology 20050101

• Sodium magnetic resonance imaging of chemotherapeutic response in a rat glioma.

  Magnetic resonance in medicine 20050101

• Cerebral edema associated with Gliadel wafers: two case studies.

  Neuro-oncology 20050101

• Cyclosporine A, alpha-lnterferon and interleukin-2 following chemotherapy with BCNU, DTIC, cisplatin, and tamoxifen: a phase II study in advanced melanoma.

  Cancer investigation 20050101

• Combination chemotherapy with carmustine and cisplatin followed by procarbazine, lomustine, and vincristine for adult high-grade astrocytoma.

  Chang Gung medical journal 20050101

• Synthesis and characterization of polyanhydride for local BCNU delivery carriers.

  Bio-medical materials and engineering 20050101

• [Combined treatment of glyal and metastatic tumors of the brain].

  Vestnik khirurgii imeni I. I. Grekova 20050101

• FNAB cytology of extra-cranial metastasis of glioblastoma multiforme may resemble a lung primary: a diagnostic pitfall.

  CytoJournal 20050101

• Hodgkin's disease as unusual presentation of post-transplant lymphoproliferative disorder after autologous hematopoietic cell transplantation for malignant glioma.

  BMC cancer 20050101

• Long-term disease-free survival in advanced melanomas treated with nitrosoureas: mechanisms and new perspectives.

  BMC cancer 20050101

• Local delivery of doxorubicin for the treatment of malignant brain tumors in rats.

  Anticancer research 20050101

• Redox properties of novel antioxidant 5,8-Dihydroxycoumarin: implications for its prooxidant cytotoxicity.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20050101

• Platinated DNA adducts enhance poisoning of DNA topoisomerase I by camptothecin.

  The Journal of biological chemistry 20041224

• 2-Chloroethyl-3-sarcosinamide-1-nitrosourea (SarCNU) inhibits prostate carcinoma cell growth via p53-dependent and p53-independent pathways.

  Cancer 20041215

• Cancer therapy with a replicating oncolytic adenovirus targeting the hypoxic microenvironment of tumors.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20041215

• Ex vivo expansion of megakaryocyte precursor cells in autologous stem cell transplantation for relapsed malignant lymphoma.

  Bone marrow transplantation 20041201

• Low electric field enhanced chemotherapy can cure mice with CT-26 colon carcinoma and induce anti-tumour immunity.

  Clinical and experimental immunology 20041201

• Second-line chemotherapy with irinotecan plus carmustine in glioblastoma recurrent or progressive after first-line temozolomide chemotherapy: a phase II study of the Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO).

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20041201

• Therapeutic efficacy of DTI-015 using diffusion magnetic resonance imaging as an early surrogate marker.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20041201

• Phase I study for poor-prognosis lymphoma: augmentation of the 'BEAM' regimen with escalating dose melphalan using amifostine cytoprotection and autologous hematopoietic stem cell transplantation--a preliminary report.

  Seminars in oncology 20041201

• Enhancement of genotoxic effects in the comet assay with human blood samples by aphidicolin.

  Toxicology letters 20041128

• In vivo release from a drug delivery MEMS device.

  Journal of controlled release : official journal of the Controlled Release Society 20041124

• Alkylation damage in DNA and RNA--repair mechanisms and medical significance.

  DNA repair 20041102

• Hematopoietic stem cell gene therapy of murine protoporphyria by methylguanine-DNA-methyltransferase-mediated in vivo drug selection.

  Gene therapy 20041101

• Randomized comparison of stereotactic radiosurgery followed by conventional radiotherapy with carmustine to conventional radiotherapy with carmustine for patients with glioblastoma multiforme: report of Radiation Therapy Oncology Group 93-05 protocol.

  International journal of radiation oncology, biology, physics 20041101

• The use of high-dose cyclophosphamide, carmustine, and thiotepa plus autologous hematopoietic stem cell transplantation as consolidation therapy for high-risk primary breast cancer after primary surgery or neoadjuvant chemotherapy.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20041101

• Phase II feasibility and pharmacokinetic study of concurrent administration of trastuzumab and high-dose chemotherapy in advanced HER2+ breast cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20041101

• Invasive phenotype observed in 1,3-bis(2-chloroethyl)-1-nitrosourea-resistant sublines of 9L rat glioma cells: a tumor model mimicking a recurrent malignant glioma.

  Journal of neurosurgery 20041101

• How effective is BCNU in recurrent glioblastoma in the modern era? A phase II trial.

  Neurology 20041012

• A spinal cord intravascular lymphomatosis with exceptionally good outcome.

  Neurology 20041012

• Functional significance of the pentose phosphate pathway and glutathione reductase in the antioxidant defenses of human sperm.

  Biology of reproduction 20041001

• Systemic BCNU enhances the efficacy of local delivery of a topoisomerase I inhibitor against malignant glioma.

  Cancer chemotherapy and pharmacology 20041001

• High-dose CEB vs BEAM with autologous stem cell transplant in lymphoma.

  Bone marrow transplantation 20041001

• Fatal pulmonary fibrosis associated with BCNU: the relative role of platelet-derived growth factor-B, insulin-like growth factor I, transforming growth factor-beta1 and cyclooxygenase-2.

  Bone marrow transplantation 20041001

• A long-term follow-up of 33 patients with non-Hodgkin's lymphoma who received the BEAM high-dose intensification regimen with cytokine support only and no transplant.

  Leukemia 20041001

• Results of autologous transplantation in lymphoma are not improved by increasing the dose of etoposide in the BEAM regimen: a single-centre sequential-cohort study.

  Bone marrow transplantation 20041001

• In vitro cytotoxicity of epigallocatechin gallate and tea extracts to cancerous and normal cells from the human oral cavity.

  Basic & clinical pharmacology & toxicology 20041001

• Combination chemotherapy of BCNU and Didox acts synergystically in 9L glioma cells.

  Nucleosides, nucleotides & nucleic acids 20041001

• Does stereotactic eligibility for the treatment of glioblastoma cause selection bias in randomized studies?

  American journal of clinical oncology 20041001

• [Comparision of high dose impulsion and low dose density chemotherapeutic regimens with paclitaxel plus cisplatin in advanced NSCLC].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20041001

• Enhanced in vitro invasiveness and drug resistance with altered gene expression patterns in a human lung carcinoma cell line after pulse selection with anticancer drugs.

  International journal of cancer 20040910

• 25-year study of lung fibrosis following carmustine therapy for brain tumor in childhood.

  Chest 20040901

• Brain tumor cell lines resistant to O6-benzylguanine/1,3-bis(2-chloroethyl)-1-nitrosourea chemotherapy have O6-alkylguanine-DNA alkyltransferase mutations.

  Molecular cancer therapeutics 20040901

• The glutathione reductase inhibitor carmustine induces an influx of Ca2+ in PC12 cells.

  European journal of pharmacology 20040816

• UV light increases vitamin C uptake by bovine lens epithelial cells.

  Molecular vision 20040806

• Temozolomide in paediatric high-grade glioma: a key for combination therapy?

  British journal of cancer 20040802

• Synergistic cytotoxicity of the ribonucleotide reductase inhibitor didox (3,4-dihydroxy-benzohydroxamic acid) and the alkylating agent carmustine (BCNU) in 9L rat gliosarcoma cells and DAOY human medulloblastoma cells.

  Cancer chemotherapy and pharmacology 20040801

• CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20040801

• Pharmacokinetics of O(6)-benzylguanine in pediatric patients with central nervous system tumors: a pediatric oncology group study.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20040801

• Lentivirus-mediated expression of mutant MGMTP140K protects human CD34+ cells against the combined toxicity of O6-benzylguanine and 1,3-bis(2-chloroethyl)-nitrosourea or temozolomide.

  Human gene therapy 20040801

• Interstitial lung disease associated with drug therapy.

  British journal of cancer 20040801

• Diagnosis and management of drug-associated interstitial lung disease.

  British journal of cancer 20040801

• Phase I trial of the novel taxane BMS-184476 administered in combination with carboplatin every 21 days.

  British journal of cancer 20040719

• Phase I study pilot arms of radiotherapy and carmustine with temozolomide for anaplastic astrocytoma (Radiation Therapy Oncology Group 9813): implications for studies testing initial treatment of brain tumors.

  International journal of radiation oncology, biology, physics 20040715

• 2-amino-O4-benzylpteridine derivatives: potent inactivators of O6-alkylguanine-DNA alkyltransferase.

  Journal of medicinal chemistry 20040715

• Combination of caspase transfer using the human telomerase reverse transcriptase promoter and conventional therapies for malignant glioma cells.

  International journal of oncology 20040701

• Tributyltin-sulfhydryl interaction as a cause of immunotoxicity in phagocytes of tunicates.

  Ecotoxicology and environmental safety 20040701

• Distinct responses of xenografted gliomas to different alkylating agents are related to histology and genetic alterations.

  Cancer research 20040701

• Effects on Walker 256 tumour of carmustine associated with a cholesterol-rich microemulsion (LDE).

  The Journal of pharmacy and pharmacology 20040701

• In vitro evaluation of dimethane sulfonate analogues with potential alkylating activity and selective renal cell carcinoma cytotoxicity.

  Molecular cancer therapeutics 20040701

• Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.

  Neuro-oncology 20040701

• BCNU down-regulates anti-apoptotic proteins bcl-xL and Bcl-2 in association with cell death in oligodendroglioma-derived cells.

  Journal of neuro-oncology 20040701

• Four-year survival after trans-jugular intrahepatic porto-systemic shunt for veno-occlusive disease following autologous bone marrow transplantation.

  Leukemia & lymphoma 20040701

• Primary non-Hodgkin's lymphoma of the CNS treated with CHOD/BVAM or BVAM chemotherapy before radiotherapy: long-term survival and prognostic factors.

  International journal of radiation oncology, biology, physics 20040601

• Infused CD34 cell dose, but not tumour cell content of peripheral blood progenitor cell grafts, predicts clinical outcome in patients with diffuse large B-cell lymphoma and follicular lymphoma grade 3 treated with high-dose therapy.

  British journal of haematology 20040601

• DNA damage-processing pathways involved in the eukaryotic cellular response to anticancer DNA cross-linking drugs.

  Molecular pharmacology 20040601

• [Study on MGMT assay and tumor individual predictable chemotherapy].

  Ai zheng = Aizheng = Chinese journal of cancer 20040601

• Polymorphism of human mu class glutathione transferases.

  Pharmacogenetics 20040601

• Chemotherapy in metastatic gastric cancer: population-based perceptions and practice patterns of medical oncologists.

  British journal of cancer 20040517

• Nitric oxide and BCNU chemoresistance in C6 glioma cells: role of S-nitrosoglutathione.

  Free radical biology & medicine 20040515

• Flavoenzyme-catalyzed redox cycling of hydroxylamino- and amino metabolites of 2,4,6-trinitrotoluene: implications for their cytotoxicity.

  Archives of biochemistry and biophysics 20040515

• Hammerhead ribozyme-mediated sensitization of human tumor cells after treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea.

  The Journal of pharmacology and experimental therapeutics 20040501

• BCNU as second line therapy for recurrent high-grade glioma previously treated with Temozolomide.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20040501

• Phase I study of involved-field radiotherapy preceding autologous stem cell transplantation for patients with high-risk lymphoma or Hodgkin's disease.

  International journal of radiation oncology, biology, physics 20040501

• Interstitial infusion of carmustine in the rat brain stem with systemic administration of O6-benzylguanine.

  Journal of neuro-oncology 20040501

• Phase II study of neoadjuvant 1, 3-bis (2-chloroethyl)-1-nitrosourea and temozolomide for newly diagnosed anaplastic glioma: a North American Brain Tumor Consortium Trial.

  Cancer 20040415

• Inhibition of cell signaling by the combi-nitrosourea FD137 in the androgen independent DU145 prostate cancer cell line.

  The Prostate 20040401

• Cloning and expression of canine O6-methylguanine-DNA methyltransferase in target cells, using gammaretroviral and lentiviral vectors.

  Human gene therapy 20040401

• A randomized trial of amifostine and carmustine-containing chemotherapy to assess lung-protective effects.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20040401

• Phase 2 trial of BCNU plus irinotecan in adults with malignant glioma.

  Neuro-oncology 20040401

• Phase 1 trial of irinotecan plus BCNU in patients with progressive or recurrent malignant glioma.

  Neuro-oncology 20040401

• Salvage chemotherapy with cyclophosphamide for recurrent, temozolomide-refractory glioblastoma multiforme.

  Cancer 20040315

• Compartmental inhibition of hepatic glutathione reductase activities by 1,3-bis(2-chloroethyl)-N-nitrosourea (BCNU) in Sprague-Dawley and Fischer-344 rats.

  Toxicology letters 20040307

• Autologous peripheral blood stem cell transplantation with BCVAC conditioning in childhood acute myeloid leukemia.

  Bone marrow transplantation 20040301

• A single prior course of BCNU-cisplatin chemotherapy has a significant deleterious effect on mobilization kinetics of otherwise untreated patients.

  Bone marrow transplantation 20040301

• Carbamoylating chemoresistance induced by cobalt pretreatment in C6 glioma cells: putative roles of hypoxia-inducible factor-1.

  British journal of pharmacology 20040301

• Cellular glutathione prevents cytolethality of monomethylarsonic acid.

  Toxicology and applied pharmacology 20040301

• A randomized phase I and pharmacological trial of sequences of 1,3-bis(2-chloroethyl)-1-nitrosourea and temozolomide in patients with advanced solid neoplasms.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20040301

• Cognitive status and quality of life after treatment for primary CNS lymphoma.

  Neurology 20040224

• Pharmacokinetics of high-dose chemotherapy.

  Bone marrow transplantation 20040201

• In vivo selection for human and murine hematopoietic cells transduced with a therapeutic MGMT lentiviral vector that inhibits HIV replication.

  Molecular therapy : the journal of the American Society of Gene Therapy 20040201

• Pattern of recurrence following local chemotherapy with biodegradable carmustine (BCNU) implants in patients with glioblastoma.

  Journal of neuro-oncology 20040201

• BEAM-alemtuzumab reduced-intensity allogeneic stem cell transplantation for lymphoproliferative diseases: GVHD, toxicity, and survival in 65 patients.

  Blood 20040115

• Metabolism of a cholesterol-rich microemulsion (LDE) in patients with multiple myeloma and a preliminary clinical study of LDE as a drug vehicle for the treatment of the disease.

  Cancer chemotherapy and pharmacology 20040101

• Recent advances in brain tumor therapy: local intracerebral drug delivery by polymers.

  Investigational new drugs 20040101

• Increased exhaled nitric oxide following autologous peripheral hematopoietic stem-cell transplantation: a potential marker of idiopathic pneumonia syndrome.

  Chest 20040101

• Medical devices of the head, neck, and spine.

  Radiographics : a review publication of the Radiological Society of North America, Inc 20040101

• Comparison of BAVC to BuCy regimens in autologous stem cell transplantation for adult patients with acute myeloid leukemia.

  Haematologica 20040101

• Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American Brain Tumor Consortium study.

  Neuro-oncology 20040101

• Hemopoietic recovery and infectious complications in breast cancer and multiple myeloma after autologous CD34+ cell-selected peripheral blood progenitor cell transplantation.

  International journal of hematology 20040101

• Clinical course and pathologic findings after Gliadel and radiotherapy for newly diagnosed malignant glioma: implications for patient management.

  Cancer investigation 20040101

• Advancing the treatment of malignant glioma: act local, think global.

  Cancer investigation 20040101

• Pre-irradiation chemotherapy for newly diagnosed high grade astrocytoma.

  Anticancer research 20040101

• Carmustine, vincristine, and prednisone in the treatment of canine lymphosarcoma.

  Journal of the American Animal Hospital Association 20040101

• Current management strategies for cutaneous T-cell lymphoma.

  Clinics in dermatology 20040101

• Myeloablative radiochemotherapy followed by autologous peripheral blood stem cell transplantation as first-line therapy in peripheral T-cell lymphomas: first results of a prospective multicenter study.

  The hematology journal : the official journal of the European Haematology Association 20040101

• Dexamethasone protected human glioblastoma U87MG cells from temozolomide induced apoptosis by maintaining Bax:Bcl-2 ratio and preventing proteolytic activities.

  Molecular cancer 20040101

• [Autologous stem-cell transplantations in children with non-Hodgkin lymphomas].

  Przeglad lekarski 20040101

• Glutathione reductase is expressed at high levels in pancreatic islet cells.

  Redox report : communications in free radical research 20040101

• [Use of dexamethasone in treatment of high- and low-grade non-Hodgkin's lymphoma].

  Voprosy onkologii 20040101

• Enzymatic redox properties of novel nitrotriazole explosives implications for their toxicity.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101

• Bis(Chloroethyl) nitrosourea.

  Report on carcinogens : carcinogen profiles 20040101

• High-dose methotrexate-based chemotherapy followed by consolidating radiotherapy in non-AIDS-related primary central nervous system lymphoma: European Organization for Research and Treatment of Cancer Lymphoma Group Phase II Trial 20962.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031215

• In vivo selection of human hematopoietic cells in a xenograft model using combined pharmacologic and genetic manipulations.

  Human gene therapy 20031210

• High-dose therapy and autologous peripheral-blood stem-cell transplantation as salvage treatment for HIV-associated lymphoma in patients receiving highly active antiretroviral therapy.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031201

• Peroxide toxicity in conditioned lens epithelial cells--evaluation of multi-defense systems.

  Experimental eye research 20031201

• High-dose chemotherapy and autologous stem cell transplantation in peripheral T-cell lymphoma: the GEL-TAMO experience.

  Annals of oncology : official journal of the European Society for Medical Oncology 20031201

• Systemic chemotherapy in the treatment of malignant melanoma.

  Expert opinion on pharmacotherapy 20031201

• Hematopoietic expression of O(6)-methylguanine DNA methyltransferase-P140K allows intensive treatment of human glioma xenografts with combination O(6)-benzylguanine and 1,3-bis-(2-chloroethyl)-1-nitrosourea.

  Molecular cancer therapeutics 20031201

• State-of-the-art treatment of high-grade brain tumors.

  Seminars in oncology 20031201

• Arguments against the routine use of currently available adjuvant chemotherapy in high-grade gliomas.

  Seminars in oncology 20031201

• A phase I (tumour site-specific) study of carboplatin and temozolomide in patients with advanced melanoma.

  British journal of cancer 20031117

• Intensive methotrexate and cytarabine followed by high-dose chemotherapy with autologous stem-cell rescue in patients with newly diagnosed primary CNS lymphoma: an intent-to-treat analysis.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031115

• In vivo selection of MGMT(P140K) lentivirus-transduced human NOD/SCID repopulating cells without pretransplant irradiation conditioning.

  The Journal of clinical investigation 20031115

• Methylguanine methyltransferase-mediated in vivo selection and chemoprotection of allogeneic stem cells in a large-animal model.

  The Journal of clinical investigation 20031115

• Cytotoxicity, DNA damage, and apoptosis induced by new fotemustine analogs on human melanoma cells in relation to O6-methylguanine DNA-methyltransferase expression.

  The Journal of pharmacology and experimental therapeutics 20031101

• Miscoding properties of 1,N6-ethanoadenine, a DNA adduct derived from reaction with the antitumor agent 1,3-bis(2-chloroethyl)-1-nitrosourea.

  Mutation research 20031029

• O6-methylguanine-DNA-methyltransferase expression and gene polymorphisms in relation to chemotherapeutic response in metastatic melanoma.

  British journal of cancer 20031020

• Response of recurrent anaplastic ependymoma to a combination of tamoxifen and isotretinoin.

  Neurology 20031014

• Polymorphic variation in GSTP1 modulates outcome following therapy for multiple myeloma.

  Blood 20031001

• Application of the CFU-GM assay to predict acute drug-induced neutropenia: an international blind trial to validate a prediction model for the maximum tolerated dose (MTD) of myelosuppressive xenobiotics.

  Toxicological sciences : an official journal of the Society of Toxicology 20031001

• Ex vivo B cell depletion using the Eligix B Cell SC system and autologous peripheral blood stem cell transplantation in patients with follicular non-Hodgkin's lymphoma.

  Bone marrow transplantation 20031001

• Blockage of abasic site repair enhances antitumor efficacy of 1,3-bis-(2-chloroethyl)-1-nitrosourea in colon tumor xenografts.

  Molecular cancer therapeutics 20031001

• Management of mycosis fungoides: Part 2. Treatment.

  Oncology (Williston Park, N.Y.) 20031001

• Adoptive transfer of costimulated T cells induces lymphocytosis in patients with relapsed/refractory non-Hodgkin lymphoma following CD34+-selected hematopoietic cell transplantation.

  Blood 20030915

• Enhanced DNA excision repair in CCRF-CEM cells resistant to 1,3-bis(2-chloroethyl)-1-nitrosourea, quantitated using the single cell gel electrophoresis (Comet) assay.

  Biochemical pharmacology 20030915

• Neuro-Oncology Working Group 01 trial of nimustine plus teniposide versus nimustine plus cytarabine chemotherapy in addition to involved-field radiotherapy in the first-line treatment of malignant glioma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030901

• A bicistronic SIN-lentiviral vector containing G156A MGMT allows selection and metabolic correction of hematopoietic protoporphyric cell lines.

  The journal of gene medicine 20030901

• Regulation of glutathione in cardiac myocytes.

  Journal of molecular and cellular cardiology 20030901

• [Study on drug delivery of the 3H-BCNU polylacties acid released agents on gliosarcoma].

  Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20030901

• Treatment of lymphoma relapses after allogeneic hematopoietic stem cell transplantation with intensive chemotherapy followed by infusion of hematopoietic stem cell from the original donor.

  Annals of hematology 20030901

• Sensitization of pancreatic tumor xenografts to carmustine and temozolomide by inactivation of their O6-Methylguanine-DNA methyltransferase with O6-benzylguanine or O6-benzyl-2'-deoxyguanosine.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20030901

• First European case of serotype A MATa Cryptococcus neoformans infection.

  Emerging infectious diseases 20030901

• Local delivery of minocycline and systemic BCNU have synergistic activity in the treatment of intracranial glioma.

  Journal of neuro-oncology 20030901

• Semichronic inhibition of glutathione reductase promotes oxidative damage to proteins and induces both transcription and translation of tyrosine hydroxylase in the nigrostriatal system.

  Free radical research 20030901

• Ion dependence of cytotoxicity of carmustine against PC12 cells.

  European journal of pharmacology 20030829

• Effect of spermine synthase on the sensitivity of cells to anti-tumour agents.

  The Biochemical journal 20030801

• Testicular plasmacytoma with bone dissemination without medullary plasmacytosis.

  Annals of hematology 20030801

• Cytotoxicity of RH1 and related aziridinylbenzoquinones: involvement of activation by NAD(P)H:quinone oxidoreductase (NQO1) and oxidative stress.

  Archives of biochemistry and biophysics 20030801

• Human-yeast chimeric repair protein protects mammalian cells against alkylating agents: enhancement of MGMT protection.

  Cancer gene therapy 20030801

• A mathematical model for reconstitution of granulopoiesis after high dose chemotherapy with autologous stem cell transplantation.

  Journal of mathematical biology 20030801

• Low hospital mortality in patients with acute interstitial pneumonia.

  Chest 20030801

• Recombinant human erythropoietin, epoetin beta, in patients with relapsed lymphoma treated with aggressive sequential salvage chemotherapy--results of a randomized trial.

  Annals of hematology 20030801

• Summary version of the Standards, Options and Recommendations for the management of adult patients with intracranial glioma (2002).

  British journal of cancer 20030801

• Gliadel for pituitary adenomas and craniopharyngiomas.

  Neurosurgery 20030801

• The value of augmented preparative regimens combined with an autologous bone marrow transplant for the management of relapsed or refractory Hodgkin disease: a Southwest Oncology Group phase II trial.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20030801

• Pharmacokinetics of O6-benzylguanine (NSC637037) and its metabolite, 8-oxo-O6-benzylguanine.

  Journal of clinical pharmacology 20030801

• Drug selection of mutant methylguanine methyltransferase from different oncoretroviral backbones results in multilineage hematopoietic transgene expression in primary and secondary recipients.

  Journal of hematotherapy & stem cell research 20030801

• Gliadel therapy given for first resection of malignant glioma: a single centre study of the potential use of Gliadel.

  British journal of neurosurgery 20030801

• Synergistic augmentation of antimicrotubule agent-induced cytotoxicity by a phosphoinositide 3-kinase inhibitor in human malignant glioma cells.

  Cancer research 20030715

• Development of resistance to a trinuclear platinum complex in ovarian carcinoma cells.

  International journal of cancer 20030710

• Candidemia in women with breast carcinoma treated with high-dose chemotherapy and autologous bone marrow transplantation.

  Cancer 20030701

• Myeloablation is not required to select and maintain expression of the drug-resistance gene, mutant MGMT, in primary and secondary recipients.

  Molecular therapy : the journal of the American Society of Gene Therapy 20030701

• Quality of life evaluation in a randomised trial of chemotherapy versus bio-chemotherapy in advanced melanoma patients.

  European journal of cancer (Oxford, England : 1990) 20030701

• Enhancement of platinum-induced cytotoxicity by O6-benzylguanine.

  Molecular cancer therapeutics 20030701

• BEAC or BEAM for high-dose therapy in patients with non-Hodgkin's lymphoma? A single centre analysis on toxicity and efficacy.

  Leukemia & lymphoma 20030701

• Phase II trial of thalidomide and carmustine for patients with recurrent high-grade gliomas.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030615

• Myeloid clonogenic assays for comparison of the in vitro toxicity of alkylating agents.

  Toxicology in vitro : an international journal published in association with BIBRA 20030601

• Idiopathic pneumonia syndrome after high-dose chemotherapy and autologous hematopoietic stem cell transplantation for high-risk breast cancer.

  Bone marrow transplantation 20030601

• Non-hodgkins lymphoma.

  Clinical evidence 20030601

• Permeation of cytotoxic formulations through swatches from selected medical gloves.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20030515

• High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma.

  The New England journal of medicine 20030508

• The surgical bed after BCNU polymer wafer placement for recurrent glioma: serial assessment on CT and MR imaging.

  AJR. American journal of roentgenology 20030501

• The emerging role of irinotecan (CPT-11) in the treatment of malignant glioma in brain tumors.

  Cancer 20030501

• Dose escalation of carmustine in surgically implanted polymers in patients with recurrent malignant glioma: a New Approaches to Brain Tumor Therapy CNS Consortium trial.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030501

• Upper lobe pulmonary fibrosis associated with high-dose chemotherapy containing BCNU for bone marrow transplantation.

  Mayo Clinic proceedings 20030501

• Interferon-gamma for delayed pulmonary toxicity syndrome resistant to steroids.

  Bone marrow transplantation 20030501

• Formation of DNA adducts and tumor growth delay following intratumoral administration of DTI-015.

  Journal of neuro-oncology 20030501

• A hybrid form of myeloid/NK-cell acute leukemia and myeloid/NK-cell precursor acute leukemia.

  Human pathology 20030501

• Treatment of relapsing refractory diffuse large cell lymphoma after matched unrelated donor bone marrow transplant with immunosuppression withdrawal and rituximab.

  Leukemia & lymphoma 20030501

• Synthesis and antifilarial evaluation of N1,Nn- xylofuranosylated diaminoalkanes.

  Bioorganic & medicinal chemistry 20030417

• Allogeneic stem-cell transplantation from related and unrelated donors in older patients with myeloid leukemia.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030415

• Phase III study comparing three cycles of infusional carmustine and cisplatin followed by radiation therapy with radiation therapy and concurrent carmustine in patients with newly diagnosed supratentorial glioblastoma multiforme: Eastern Cooperative Oncology Group Trial 2394.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030415

• Salvage treatment with etoposide (VP-16), ifosfamide and cytarabine (Ara-C) for patients with recurrent primary central nervous system lymphoma.

  European journal of haematology 20030401

• Local immunotherapy with interleukin-2 delivered from biodegradable polymer microspheres combined with interstitial chemotherapy: a novel treatment for experimental malignant glioma.

  Neurosurgery 20030401

• A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma.

  Neuro-oncology 20030401

• Preliminary report of a phase I study of combination chemotherapy and humanized A33 antibody immunotherapy in patients with advanced colorectal cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20030401

• O6-methyl-guanine-DNA methyltransferase methylation in serum and tumor DNA predicts response to 1,3-bis(2-chloroethyl)-1-nitrosourea but not to temozolamide plus cisplatin in glioblastoma multiforme.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20030401

• Phase I trial of high dose paracetamol and carmustine in patients with metastatic melanoma.

  Melanoma research 20030401

• High-dose BCNU followed by autologous hematopoietic stem cell transplantation in supratentorial high-grade malignant gliomas: a retrospective analysis of 114 patients.

  Bone marrow transplantation 20030401

• Chemotherapy and bio-chemotherapy in patients with advanced melanoma: combination therapy with a nitrosourea.

  Journal of chemotherapy (Florence, Italy) 20030401

• Bexarotene gel: a new skin-directed treatment option for cutaneous T-cell lymphomas.

  Journal of drugs in dermatology : JDD 20030401

• Risk factors for postcraniotomy surgical site infection after 1,3-bis (2-chloroethyl)-1-nitrosourea (Gliadel) wafer placement.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030315

• [Bacteremia due to Capnocytophaga spp.: two cases].

  Enfermedades infecciosas y microbiologia clinica 20030301

• Decreased GSSG reductase activity enhances cellular zinc toxicity in three human lung cell lines.

  Archives of toxicology 20030301

• Camptothecin analogs in malignant gliomas: comparative analysis and characterization.

  Journal of neurosurgery 20030301

• BEAM allogeneic transplantation for patients with Hodgkin's disease who relapse after autologous transplantation is safe and effective.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20030301

• High-dose cyclophosphamide, BCNU, and VP-16 (CBV) conditioning before allogeneic stem cell transplantation for patients with non-Hodgkin's lymphoma.

  Bone marrow transplantation 20030301

• [Evidence-based radiation therapy for primary brain tumors].

  Gan to kagaku ryoho. Cancer & chemotherapy 20030301

• Stress-responsive JNK mitogen-activated protein kinase mediates aspirin-induced suppression of B16 melanoma cellular proliferation.

  British journal of pharmacology 20030301

• Oxidative modulation of the glutathione-redox couple enhances lipopolysaccharide-induced interleukin 12 P40 production by a mouse macrophage cell line, J774A.1.

  Free radical research 20030301

• Survival with dacarbazine and fotemustine in newly diagnosed glioblastoma multiforme.

  British journal of cancer 20030224

• Pharmacokinetic, biochemical and clinical effects of dimethyltriazenoimidazole-4-carboxamide-bischloroethylnitrosourea combination therapy in patients with advanced breast cancer.

  International journal of cancer 20030220

• Factors influencing outcome and incidence of long-term complications in children who underwent autologous stem cell transplantation for acute myeloid leukemia in first complete remission.

  Blood 20030215

• Temozolomide induces apoptosis and senescence in glioma cells cultured as multicellular spheroids.

  British journal of cancer 20030210

• The effect of O6-alkylguanine-DNA alkyltransferase and mismatch repair activities on the sensitivity of human melanoma cells to temozolomide, 1,3-bis(2-chloroethyl)1-nitrosourea, and cisplatin.

  The Journal of pharmacology and experimental therapeutics 20030201

• Inhibition of oral cancer cell growth by adenovirusMnSOD plus BCNU treatment.

  Free radical biology & medicine 20030201

• Low molecular weight heparin treatment for malignant melanoma: a pilot clinical trial.

  Thrombosis and haemostasis 20030201

• [Foliculitis in a patient with Hodkins disease].

  Enfermedades infecciosas y microbiologia clinica 20030201

• High-dose chemotherapy with autologous stem cell rescue in children with retinoblastoma.

  Bone marrow transplantation 20030201

• Synchronous occurrence of glioblastoma multiforme and esophageal adenocarcinoma.

  The American surgeon 20030201

• MRP1-transfected cells do not show increased resistance against oxidative stress.

  Free radical research 20030201

• Potentiation of chemotherapeutic agents following antagonism of nuclear factor kappa B in human gliomas.

  Journal of neuro-oncology 20030201

• BCNU-loaded poly(D, L-lactide-co-glycolide) wafer and antitumor activity against XF-498 human CNS tumor cells in vitro.

  International journal of pharmaceutics 20030130

• Fructose-1,6-bisphosphate preserves intracellular glutathione and protects cortical neurons against oxidative stress.

  Brain research 20030117

• SarCNU, a nitrosourea analog on a day 1, 5, and 9 oral schedule: a phase I and pharmacokinetic study in patients with advanced solid tumors.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030115

• High-dose therapy in diffuse large cell lymphoma: results and prognostic factors in 452 patients from the GEL-TAMO Spanish Cooperative Group.

  Annals of oncology : official journal of the European Society for Medical Oncology 20030101

• Inhibition of telomerase increases resistance of melanoma cells to temozolomide, but not to temozolomide combined with poly (adp-ribose) polymerase inhibitor.

  Molecular pharmacology 20030101

• Growth inhibition of human malignant glioma cells induced by the PI3-K-specific inhibitor.

  Journal of neurosurgery 20030101

• [The role of the regional (intra-arterial) chemotherapy in the treatment of hepatic metastases of colorectal cancer].

  Medicina (Kaunas, Lithuania) 20030101

• Stereotactic injection of DTI-015 into recurrent malignant gliomas: phase I/II trial.

  Neoplasia (New York, N.Y.) 20030101

• DTI-015 produces cures in T9 gliosarcoma.

  Neoplasia (New York, N.Y.) 20030101

• [Effectiveness of dose-intensive polychemotherapy with autologous hemopoietic cell transplantation for high-grade non-Hodgkin lymphoma].

  Voprosy onkologii 20030101

• SarCNU mediates selection of P140K methylguanine-DNA-methyltransferase transduced human CD34(+) cells in vitro.

  Blood cells, molecules & diseases 20030101

• [Chemotherapy in combination with laser coagulation or interstitial hyperthermia--effective combined therapy for disseminated skin melanoma].

  Voprosy onkologii 20030101

• Current chemotherapy for glioblastoma.

  Cancer journal (Sudbury, Mass.) 20030101

• Intracavitary chemotherapy for glioblastoma: present status and future directions.

  Acta neurochirurgica. Supplement 20030101

• High-dose therapy and autologous stem cell transplantation in relapsed and refractory Hodgkin's disease: outcome based on a prognostic model.

  Acta haematologica 20030101

• Topical carmustine (BCNU) in the treatment of mycosis fungoides.

  Dermatologic therapy 20030101

• New drugs and combinations for malignant glioma.

  Forum (Genoa, Italy) 20030101

• Regulation of intracellular glutathione levels in erythrocytes infected with chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum.

  The Biochemical journal 20021215

• Chemoresistant or aggressive lymphoma predicts for a poor outcome following reduced-intensity allogeneic progenitor cell transplantation: an analysis from the Lymphoma Working Party of the European Group for Blood and Bone Marrow Transplantation.

  Blood 20021215

• Stabilization and preformulation of anticancer drug--SarCNU.

  International journal of pharmaceutics 20021205

• Recurrent malignant glioma in adults.

  Current treatment options in oncology 20021201

• Pulmonary complications in survivors of childhood and adolescent cancer. A report from the Childhood Cancer Survivor Study.

  Cancer 20021201

• 1-beta-D-arabinofuranosylcytosine is cytotoxic in quiescent normal lymphocytes undergoing DNA excision repair.

  Japanese journal of cancer research : Gann 20021201

• Intra-arterial ACNU and carboplatin versus intravenous chemotherapy with cisplatin and BCNU in newly diagnosed patients with glioblastoma.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20021201

• Randomized study to evaluate the use of high-dose therapy as part of primary treatment for 'aggressive' lymphoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20021115

• The toxicity and efficacy of donor lymphocyte infusions given after reduced-intensity conditioning allogeneic stem cell transplantation.

  Blood 20021101

• Vanishing corneal epithelial crystals following thalidomide induced resolution of myeloma related paraproteinaemia.

  The British journal of ophthalmology 20021101

• Toxicity of intracranial and intraperitoneal O6-benzyl guanine in combination with BCNU delivered locally in a mouse model.

  Cancer chemotherapy and pharmacology 20021101

• Alkylator-induced DNA excision repair in human leukemia CCRF-CEM cells in vitro, measured using the single-cell gel electrophoresis (comet) assay.

  International journal of hematology 20021101

• Development of an in vitro chemo-radiation response assay for cervical carcinoma.

  Gynecologic oncology 20021101

• Treatment of paediatric pontine glioma with oral trophosphamide and etoposide.

  British journal of cancer 20021021

• Fluid shear stress attenuates hydrogen peroxide-induced c-Jun NH2-terminal kinase activation via a glutathione reductase-mediated mechanism.

  Circulation research 20021018

• Gliomatosis cerebri: molecular pathology and clinical course.

  Annals of neurology 20021001

• Chemoimmunohormonal therapy with carmustine, dacarbazine, cisplatin, tamoxifen, and interferon for metastatic melanoma: a prospective phase II study.

  American journal of clinical oncology 20021001

• Inhibition of O6-alkylguanine-DNA alkyltransferase by O6-benzyl-N2-acetylguanosine increases chloroethylnitrosourea-induced apoptosis in Mer+ human melanoma cells.

  Melanoma research 20021001

• Allogeneic stem cell transplantation in treatment of aggressive lymphomas: case series.

  Croatian medical journal 20021001

• Systemic chemotherapy for the treatment of metastatic melanoma.

  Seminars in oncology 20021001

• Inhibition of glutathione-related enzymes augments LPS-mediated cytokine biosynthesis: involvement of an IkappaB/NF-kappaB-sensitive pathway in the alveolar epithelium.

  International immunopharmacology 20021001

• Chemosensitization of carmustine with maitake beta-glucan on androgen-independent prostatic cancer cells: involvement of glyoxalase I.

  Journal of alternative and complementary medicine (New York, N.Y.) 20021001

• Accumulation of glutathione disulfide mediates NF-kappaB activation during immune stimulation with CpG DNA.

  Antisense & nucleic acid drug development 20021001

• [Experimental study of combination therapy against human glioma xenograft by differentiation-inducing agent and cytotoxic chemotherapeutic drug].

  Ai zheng = Aizheng = Chinese journal of cancer 20021001

• Phase I study of fotemustine in pediatric patients with refractory brain tumors.

  Cancer 20020915

• Increased excitability and decreased sensitivity to GABA in an animal model of dysplastic cortex.

  Epilepsia 20020901

• Long-term results (12 years) of high-dose therapy in 127 patients with de novo multiple myeloma.

  Leukemia 20020901

• In vitro and in vivo characterization of graft-versus-tumor responses in melanoma patients after allogeneic peripheral blood stem cell transplantation.

  International journal of cancer 20020901

• The apurinic/apyrimidinic endonuclease activity of Ape1/Ref-1 contributes to human glioma cell resistance to alkylating agents and is elevated by oxidative stress.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20020901

• O6-benzylguanine-mediated enhancement of chemotherapy.

  Molecular cancer therapeutics 20020901

• Goosebumps.

  Lancet (London, England) 20020831

• Oxidative stress and inflammation contribute to lung toxicity after a common breast cancer chemotherapy regimen.

  American journal of physiology. Lung cellular and molecular physiology 20020801

• The epidermal growth factor receptor pathway mediates resistance to sequential administration of radiation and chemotherapy in primary human glioblastoma cells in a RAS-dependent manner.

  Cancer research 20020801

• A case of treatment-related myelodysplastic syndrome and acute myelogenous leukemia following high-dose chemotherapy with autologous stem cell transplantation for non-Hodgkin's lymphoma.

  Journal of Korean medical science 20020801

• The Brain Tumor Cooperative Group NIH Trial 87-01: a randomized comparison of surgery, external radiotherapy, and carmustine versus surgery, interstitial radiotherapy boost, external radiation therapy, and carmustine.

  Neurosurgery 20020801

• Induced leukemia and antineoplastic agent carmustine cause permanent changes in craniofacial growth of immature rats.

  Orthodontics & craniofacial research 20020801

• Acute myocardial ischemia after high-dose therapy with BEAM regimen.

  Bone marrow transplantation 20020801

• Evaluation of the efficiency of chemotherapy in in vivo orthotopic models of human glioma cells with and without 1p19q deletions and in C6 rat orthotopic allografts serving for the evaluation of surgery combined with chemotherapy.

  Cancer 20020801

• A randomized trial of chemotherapy with carmustine, etoposide, cytarabine, and melphalan (BEAM) plus peripheral stem cell transplantation (PBSCT) vs single-agent high-dose chemotherapy followed by BEAM plus PBSCT in patients with relapsed Hodgkin's disease (HD-R2).

  Annals of hematology 20020801

• Alkylation resistance of E. coli cells expressing different isoforms of human alkyladenine DNA glycosylase (hAAG).

  DNA repair 20020717

• Novel mutation of topoisomerase I in rendering cells resistant to camptothecin.

  Cancer research 20020701

• Unusual implantation site of a port-a-cath system via the right femoral vein.

  Journal of cancer research and clinical oncology 20020701

• Mechanisms of resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea in human medulloblastoma and rhabdomyosarcoma.

  Molecular cancer therapeutics 20020701

• A multidrug combination designed for reversing resistance to BCNU in glioblastoma multiforme.

  Neurology 20020625

• Aggressive conventional chemotherapy compared with high-dose chemotherapy with autologous haemopoietic stem-cell transplantation for relapsed chemosensitive Hodgkin's disease: a randomised trial.

  Lancet (London, England) 20020615

• Heterogeneity of O6-alkylguanine DNA-alkyltransferase expression in human breast tumours.

  British journal of cancer 20020605

• Safety of thrice-daily hyperfractionated radiation and BCNU for high-grade gliomas.

  International journal of radiation oncology, biology, physics 20020601

• Chemotherapy-induced O(6)-benzylguanine-resistant alkyltransferase mutations in mismatch-deficient colon cancer.

  Cancer research 20020601

• Composite mycosis fungoides and B-cell chronic lymphocytic leukemia.

  Annals of diagnostic pathology 20020601

• Association of carmustine with a lipid emulsion: in vitro, in vivo and preliminary studies in cancer patients.

  Cancer chemotherapy and pharmacology 20020601

• Successful therapy with high-dose steroids and cyclosporine for the treatment of carmustine-mediated lung injury.

  Annals of hematology 20020601

• Predictors for pneumonitis during locoregional radiotherapy in high-risk patients with breast carcinoma treated with high-dose chemotherapy and stem-cell rescue.

  Cancer 20020601

• [Primary cardiac lymphoma: cytological diagnosis and treatment with response to polychemotherapy and hematopoietic precursor autotransplant. Presentation of a case a review of the literature].

  Anales de medicina interna (Madrid, Spain : 1984) 20020601

• Autologous stem cell transplantation in patients with mantle cell lymphoma.

  Leukemia & lymphoma 20020601

• Efficacy of BCNU and paclitaxel loaded subcutaneous implants in the interstitial chemotherapy of U-87 MG human glioblastoma xenografts.

  International journal of pharmaceutics 20020515

• Shortened first-line high-dose chemotherapy for patients with poor-prognosis aggressive lymphoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020515

• Phase II trial of carmustine plus O(6)-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020501

• Autologous transplantation for aggressive non-Hodgkin's lymphoma: results of a randomized trial evaluating graft source and minimal residual disease.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020501

• Clinical relevance of MGMT in the treatment of cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020501

• Management of tumor bed cysts after chemotherapeutic wafer implantation. Report of four cases.

  Journal of neurosurgery 20020501

• A major human arsenic metabolite, dimethylarsinic acid, requires reduced glutathione to induce apoptosis.

  Chemical research in toxicology 20020501

• Factors affecting progression-free survival in hormone-dependent metastatic breast cancer patients receiving high-dose chemotherapy and hematopoietic progenitor cell transplantation: role of maintenance endocrine therapy.

  Bone marrow transplantation 20020501

• NO-mediated chemoresistance in C6 glioma cells.

  Annals of the New York Academy of Sciences 20020501

• Synergistic effect of genistein and BCNU on growth inhibition and cytotoxicity of glioblastoma cells.

  Journal of neuro-oncology 20020501

• Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

  The Journal of biological chemistry 20020419

• Phase II study of irinotecan (CPT-11) in children with high-risk malignant brain tumors: the Duke experience.

  Neuro-oncology 20020401

• Lentiviral transduction of P140K MGMT into human CD34(+) hematopoietic progenitors at low multiplicity of infection confers significant resistance to BG/BCNU and allows selection in vitro.

  Molecular therapy : the journal of the American Society of Gene Therapy 20020401

• In vitro pharmacokinetics and pharmacodynamics of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU).

  Biochemical pharmacology 20020401

• Antiproliferative effect of thalidomide alone and combined with carmustine against C6 rat glioma.

  International journal of experimental pathology 20020401

• Gateways to Clinical Trials.

  Methods and findings in experimental and clinical pharmacology 20020401

• Autologous stem cell transplantation for Hodgkin's lymphoma: results and prognostic factors in 51 high-risk patients.

  Advances in clinical pathology : the official journal of Adriatic Society of Pathology 20020401

• Cisplatin, dacarbazine with or without subcutaneous interleukin-2, and interferon alpha-2b in advanced melanoma outpatients: results from an Italian multicenter phase III randomized clinical trial.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020315

• A phase II trial of the vitamin D analogue Seocalcitol (EB1089) in patients with inoperable pancreatic cancer.

  British journal of cancer 20020304

• Improvement of combination chemotherapy tolerance by introduction of polycistronic retroviral vector drug resistance genes MGMT and MDR1 into human umbilical cord blood CD34+ cells.

  Leukemia research 20020301

• The expression of glutathione reductase in the male reproductive system of rats supports the enzymatic basis of glutathione function in spermatogenesis.

  European journal of biochemistry 20020301

• Association of high-dose cyclophosphamide, cisplatin, and carmustine pharmacokinetics with survival, toxicity, and dosing weight in patients with primary breast cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20020301

• Widespread skin-limited adult Langerhans cell histiocytosis: long-term follow-up with good response to interferon alpha.

  Clinical and experimental dermatology 20020301

• Apoptosis induced by adenovirus-mediated p53 gene transfer in human glioma correlates with site-specific phosphorylation.

  Cancer research 20020215

• Inhibition of glutathione S-transferases by antimalarial drugs possible implications for circumventing anticancer drug resistance.

  International journal of cancer 20020210

• Comparison of the efficacy of two different dosage dacarbazine-based regimens and two regimens without dacarbazine in metastatic melanoma: a single-centre randomized four-arm study.

  Melanoma research 20020201

• Positron emission tomography with [18F]2-fluoro-D-2-deoxyglucose (FDG-PET) predicts relapse of malignant lymphoma after high-dose therapy with stem cell transplantation.

  Leukemia 20020201

• Point mutations of the BCL-6 gene: clinical and prognostic correlation in B-diffuse large cell lymphoma.

  Leukemia 20020201

• Thromboxane synthase inhibitors induce apoptosis in migration-arrested glioma cells.

  Neurosurgery 20020201

• Influence of antioxidant depletion on nitrergic relaxation in the pig gastric fundus.

  British journal of pharmacology 20020201

• Redox signaling-mediated regulation of lipopolysaccharide-induced proinflammatory cytokine biosynthesis in alveolar epithelial cells.

  Antioxidants & redox signaling 20020201

• Polymer delivery of camptothecin against 9L gliosarcoma: release, distribution, and efficacy.

  Journal of neuro-oncology 20020201

• Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA.

  Oncogene 20020131

• Combination chemotherapy with or without s.c. IL-2 and IFN-alpha: results of a prospectively randomized trial of the Cooperative Advanced Malignant Melanoma Chemoimmunotherapy Group (ACIMM).

  British journal of cancer 20020121

• [Chemotherapy of recurrent supratentorial malignant gliomas (phase II study)].

  Ideggyogyaszati szemle 20020120

• Intensive salvage therapy with high-dose chemotherapy for patients with advanced Hodgkin's disease in relapse or failure after initial chemotherapy: results of the Groupe d'Etudes des Lymphomes de l'Adulte H89 Trial.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020115

• The polymorphic human glutathione transferase T1-1, the most efficient glutathione transferase in the denitrosation and inactivation of the anticancer drug 1,3-bis(2-chloroethyl)-1-nitrosourea.

  Biochemical pharmacology 20020115

• Escherichia coli FPG and human OGG1 reduce DNA damage and cytotoxicity by BCNU in human lung cells.

  American journal of physiology. Lung cellular and molecular physiology 20020101

• Up-regulation of K(+) channels in diabetic rat ventricular myocytes by insulin and glutathione.

  Cardiovascular research 20020101

• Importance of radiotherapy in the outcome of patients with primary CNS lymphoma: an analysis of the CHOD/BVAM regimen followed by two different radiotherapy treatments.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020101

• Age-adjusted chemotherapy for primary central-nervous system lymphoma--a pilot study.

  Acta oncologica (Stockholm, Sweden) 20020101

• Comparative cytotoxicity of carmustine (BCNU), nimustine (ACNU) and elmustine (HeCNU) after depletion of O6-alkylguanine-DNA alkyltransferase (O6-AGT).

  Anticancer research 20020101

• Pharmacokinetics of the carmustine implant.

  Clinical pharmacokinetics 20020101

• Injection of chemotherapeutic microspheres and glioma. IV: Eradicating tumors in rats.

  Cell transplantation 20020101

• Dose-intensive therapy for extensive-stage small cell lung cancer and extrapulmonary small cell carcinoma: long-term outcome.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20020101

• Ambulatory electrocardiographic evaluation of the heart in patients treated by megachemotherapy and bone marrow transplantation.

  Haematologia 20020101

• Temozolomide in second-line treatment after prior nitrosurea-based chemotherapy in glioblastoma multiforme: experience from a Portuguese institution.

  International journal of clinical pharmacology research 20020101

• Use of thrombopoietin in combination with chemotherapy and granulocyte colony-stimulating factor for peripheral blood progenitor cell mobilization.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20020101

• Cytotoxicity of natural hydroxyanthraquinones: role of oxidative stress.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101

• [High-dose chemotherapy with autologous bone marrow transplantation in children with high-risk malignant neoformations].

  Voprosy onkologii 20020101

• BCNU-DBD (Dibromodulcitol) chemotherapy of recurrent supratentorial anaplastic astrocytomas and glioblastomas.

  Neoplasma 20020101

• Pharmacological considerations of primary alkylators.

  Cancer treatment and research 20020101

• High-dose chemotherapy and hematopoietic support for patients with high-risk primary breast cancer and involvement of 4 to 9 lymph nodes.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20020101

• [Effectiveness of high-dose polychemotherapy and autologous hemopoietic cell transplantation in patients with low-grade non-Hodgkin lymphoma].

  Voprosy onkologii 20020101

• Oxygen-sensing mechanisms and the regulation of redox-responsive transcription factors in development and pathophysiology.

  Respiratory research 20020101

• High-dose chemotherapy in small-cell lung cancer.

  Anticancer research 20020101

• bis(Chloroethyl) nitrosourea.

  Report on carcinogens : carcinogen profiles 20020101

• Induction of lacI mutations in Big Blue Rat-2 cells treated with 1-(2-hydroxyethyl)-1-nitrosourea: a model system for the analysis of mutagenic potential of the hydroxyethyl adducts produced by 1,3-bis (2-chloroethyl)-1-nitrosourea.

  Mutation research 20011212

• HER-2/neu overexpression as a poor prognostic factor for patients with metastatic breast cancer undergoing high-dose chemotherapy with autologous stem cell transplantation.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20011201

• Role of cytochrome P450 isoenzymes in metabolism of O(6)-benzylguanine: implications for dacarbazine activation.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20011201

• High-dose chemotherapy and CD34-selected peripheral blood progenitor cell transplantation for patients with breast cancer metastatic to bone and/or bone marrow.

  Bone marrow transplantation 20011201

• Tandem autotransplant as first-line consolidative treatment in poor-risk aggressive lymphoma: a pilot study of 36 patients.

  Annals of oncology : official journal of the European Society for Medical Oncology 20011201

• Thoracic positron emission tomography using 18F-fluorodeoxyglucose for the evaluation of residual mediastinal Hodgkin disease.

  Blood 20011115

• High-dose therapy in patients with Hodgkin's disease: the use of selected CD34(+) cells is as safe as unmanipulated peripheral blood progenitor cells.

  Bone marrow transplantation 20011101

• A novel type of metastatically spreading subcutaneous aspergillosis without epidermal lesions following allogeneic stem cell transplantation.

  Bone marrow transplantation 20011101

• The effectiveness of the O(6)-alkylguanine-DNA alkyltransferase encoded by the ogt(ST) gene from S. typhimurium in protection against alkylating drugs, resistance to O(6)-benzylguanine and sensitisation to dibromoalkane genotoxicity.

  Mutation research 20011018

• Quinacrine enhances carmustine therapy of experimental rat glioma.

  Neurosurgery 20011001

• Levels of N7-(2-hydroxyethyl)guanine as a molecular dosimeter of drug delivery to human brain tumors.

  Neuro-oncology 20011001

• Phase I study of Gliadel wafers plus temozolomide in adults with recurrent supratentorial high-grade gliomas.

  Neuro-oncology 20011001

• Sequential tumor biopsies in early phase clinical trials of anticancer agents for pharmacodynamic evaluation.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20011001

• Induction of mild intracellular redox imbalance inhibits proliferation of CaCo-2 cells.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011001

• Considerations in the selection of an appropriate conditioning regimen for the treatment of rheumatoid arthritis by autologous peripheral blood stem cell transplantation.

  The Journal of rheumatology. Supplement 20011001

• G156A MGMT-transduced human mesenchymal stem cells can be selectively enriched by O6-benzylguanine and BCNU.

  Journal of hematotherapy & stem cell research 20011001

• Outcome and long-term side effects after synchronous radiochemotherapy for childhood brain stem gliomas.

  Pediatric neurosurgery 20011001

• Immunomodulation of early engrafted natural killer cells with interleukin-2 and interferon-alpha in autologous stem cell transplantation.

  Bone marrow transplantation 20011001

• Use of pure t-butanol as a solvent for freeze-drying: a case study.

  International journal of pharmaceutics 20010911

• Nitric oxide and free stable nitroxyl radicals in the mechanism of biological action of the spin-labeled compounds.

  Medical hypotheses 20010901

• Accelerated hazards regression model and its adequacy for censored survival data.

  Biometrics 20010901

• T-cell depletion and autologous stem cell transplantation in the management of tumour stage mycosis fungoides with peripheral blood involvement.

  British journal of haematology 20010901

• Plasma pharmacokinetics and bioavailability of 1-(2-chloroethyl)-3-sarcosinamide-1-nitrosourea after intravenous and oral administration to mice and dogs.

  Cancer chemotherapy and pharmacology 20010901

• [Role of high-dose chemotherapy with hemopoietic stem-cell support in the treatment of adult patients with high-grade glioma].

  Bulletin du cancer 20010901

• [Autograft and multiple myeloma: experience of the Intergroupe Français du Myélome].

  Bulletin du cancer 20010901

• [Expression and drug resistance of human MGMT gene in hemopoietic cells mediated by bicistronic retroviral vector].

  Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 20010901

• [A bicistronic retroviral vector containing MGMT and MDR1 drug resistance genes transfer into human umbilical cord blood CD34+ cells to improve combination chemotherapy tolerance].

  Shi yan sheng wu xue bao 20010901

• Adenovirally-mediated transfer of E2F-1 potentiates chemosensitivity of human glioma cells to temozolomide and BCNU.

  International journal of oncology 20010801

• Temozolomide in combination with other cytotoxic agents.

  Seminars in oncology 20010801

• Pulmonary toxicity syndrome following CDEP (cyclophosphamide, dexamethasone, etoposide, cisplatin) chemotherapy.

  Bone marrow transplantation 20010801

• Bcl-2 overexpression decreases BCNU sensitivity of a human glioblastoma line through enhancement of catalase activity.

  Journal of cellular biochemistry 20010801

• Diaminopurine-acridine heterodimers for specific recognition of abasic site containing DNA. Influence on the biological activity of the position of the linker on the purine ring.

  Bioorganic & medicinal chemistry letters 20010723

• A phase III study of radiation therapy plus carmustine with or without recombinant interferon-alpha in the treatment of patients with newly diagnosed high-grade glioma.

  Cancer 20010715

• Autologous hematopoietic stem cell transplantation suppresses Gd-enhanced MRI activity in MS.

  Neurology 20010710

• Biodegradable polymer implants to treat brain tumors.

  Journal of controlled release : official journal of the Controlled Release Society 20010706

• Modulation of 1,3-bis-(2-chloroethyl)-1-nitrosourea resistance in human tumor cells using hammerhead ribozymes designed to degrade O6-methylguanine DNA methyltransferase mRNA.

  The Journal of pharmacology and experimental therapeutics 20010701

• Potentiation of BCNU cytotoxicity by molecules targeting abasic lesions in DNA.

  Bioorganic & medicinal chemistry 20010701

• A CD44 survival pathway triggers chemoresistance via lyn kinase and phosphoinositide 3-kinase/Akt in colon carcinoma cells.

  Cancer research 20010701

• Acyl derivatives of demethylpenclomedine, an antitumor-active, non-neurotoxic metabolites of penclomedine.

  Cancer chemotherapy and pharmacology 20010701

• Dexamethasone, paclitaxel, etoposide, cyclophosphamide (d-TEC) and G-CSF for stem cell mobilisation in multiple myeloma.

  Bone marrow transplantation 20010701

• Autologous stem cell transplantation for follicular lymphoma: no benefit for early transplant?

  Annals of hematology 20010701

• Protection of hematopoietic cells from O(6)-alkylation damage by O(6)-methylguanine DNA methyltransferase gene transfer: studies with different O(6)-alkylating agents and retroviral backbones.

  European journal of haematology 20010701

• Amifostine does not protect malignant lymphoma cell lines from the cytotoxic effects of various chemotherapeutics in vitro.

  Leukemia & lymphoma 20010701

• Heterogeneous methylation of the O(6)-methylguanine-DNA methyltransferase promoter in immortalized IMR90 cell lines.

  International journal of oncology 20010601

• CHOD/BVAM regimen plus radiotherapy in patients with primary CNS non-Hodgkin's lymphoma.

  International journal of radiation oncology, biology, physics 20010601

• Daunorubicin continuous infusion induces more toxicity than bolus infusion in acute lymphoblastic leukemia induction regimen: a randomized study.

  Leukemia 20010601

• Anticancer therapy by overexpression of superoxide dismutase.

  Antioxidants & redox signaling 20010601

• Metastatic melanoma.

  Current treatment options in oncology 20010601

• Design, synthesis, and biological evaluation of analogues of the antitumor agent, 2-(4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy)propionic acid (XK469).

  Journal of medicinal chemistry 20010524

• Synergy between methionine stress and chemotherapy in the treatment of brain tumor xenografts in athymic mice.

  Cancer research 20010515

• Inactivation of p53 sensitizes U87MG glioma cells to 1,3-bis(2-chloroethyl)-1-nitrosourea.

  Cancer research 20010515

• Comparison of single- versus double-bolus treatments of O(6)-benzylguanine for depletion of O(6)-methylguanine DNA methyltransferase (MGMT) activity in vivo: development of a novel fluorometric oligonucleotide assay for measurement of MGMT activity.

  The Journal of pharmacology and experimental therapeutics 20010501

• Cellular titration of apoptosis with steady state concentrations of H(2)O(2): submicromolar levels of H(2)O(2) induce apoptosis through Fenton chemistry independent of the cellular thiol state.

  Free radical biology & medicine 20010501

• Enforced expression of wild-type p53 curtails the transcription of the O(6)-methylguanine-DNA methyltransferase gene in human tumor cells and enhances their sensitivity to alkylating agents.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20010501

• O6-Benzylguanine potentiates BCNU but not busulfan toxicity in hematopoietic stem cells.

  Experimental hematology 20010501

• Immunoablative therapy with autologous stem cell transplantation in the treatment of poor risk multiple sclerosis.

  Transplantation proceedings 20010501

• Shunt-related abdominal metastases in an infant with medulloblastoma: long-term remission by systemic chemotherapy and surgery.

  Journal of neuro-oncology 20010501

• Drug delivery to tumors of the central nervous system.

  Current neurology and neuroscience reports 20010501

• The role of glutathione reductase in the cytotoxicity of chromium (VI) in isolated rat hepatocytes.

  Chemico-biological interactions 20010416

• Reduction of BCNU toxicity to lung cells by high-level expression of O(6)-methylguanine-DNA methyltransferase.

  American journal of physiology. Lung cellular and molecular physiology 20010401

• Inducible nitric oxide synthase neutralizes carbamoylating potential of 1,3-bis(2-chloroethyl)-1-nitrosourea in c6 glioma cells.

  The Journal of pharmacology and experimental therapeutics 20010401

• Regulation of thioltransferase expression in human lens epithelial cells.

  Investigative ophthalmology & visual science 20010401

• 1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-(methylamino)carbonylhydrazine (101M): a novel sulfonylhydrazine prodrug with broad-spectrum antineoplastic activity.

  Cancer research 20010401

• Long-term follow-up in patients treated with Mini-BEAM as salvage therapy for relapsed or refractory Hodgkin's disease.

  British journal of haematology 20010401

• Phase II randomized study of dacarbazine, carmustine, cisplatin and tamoxifen versus dacarbazine alone in advanced melanoma patients.

  Melanoma research 20010401

• Dose escalation of cytotoxic drugs using haematopoietic growth factors: a randomized trial to determine the magnitude of increase provided by GM-CSF.

  Annals of oncology : official journal of the European Society for Medical Oncology 20010401

• Debenzylation of O(6)-benzyl-8-oxoguanine in human liver: implications for O(6)-benzylguanine metabolism.

  Biochemical pharmacology 20010315

• Both extraneuronal monoamine transporter and O(6)-methylguanine-DNA methyltransferase expression influence the antitumor efficacy of 2-chloroethyl-3-sarcosinamide- 1-nitrosourea in human tumor xenografts.

  The Journal of pharmacology and experimental therapeutics 20010301

• Protection of mammalian cells against chemotherapeutic agents thiotepa, 1,3-N,N'-bis(2-chloroethyl)-N-nitrosourea, and mafosfamide using the DNA base excision repair genes Fpg and alpha-hOgg1: implications for protective gene therapy applications.

  The Journal of pharmacology and experimental therapeutics 20010301

• Inactivation of human O(6)-alkylguanine-DNA alkyltransferase by modified oligodeoxyribonucleotides containing O(6)-benzylguanine.

  The Journal of pharmacology and experimental therapeutics 20010301

• The DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.

  The New England journal of medicine 20010301

• The DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.

  The New England journal of medicine 20010301

• The DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.

  The New England journal of medicine 20010301

• The DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.

  The New England journal of medicine 20010301

• Antimitotic antitumor agents: synthesis, structure-activity relationships, and biological characterization of N-aryl-N'-(2-chloroethyl)ureas as new selective alkylating agents.

  Journal of medicinal chemistry 20010301

• Effects of chemotherapy by 1,3-bis(2-chloroethyl)-1-nitrosourea on single-quantum- and triple-quantum-filtered 23Na and 31P nuclear magnetic resonance of the subcutaneously implanted 9L glioma.

  Cancer research 20010301

• Antiangiogenic and antitumor effects of a protein kinase Cbeta inhibitor in human T98G glioblastoma multiforme xenografts.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20010301

• Pharmacodynamics of high-dose chemotherapy.

  Current drug metabolism 20010301

• [Expression of extraneuronal monoamine transporter gene and DNA repair gene vis-à-vis with antitumor efficacy of SarCNU in human tumor xenografts].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20010301

• [Therapeutic effect on glioblastoma of chemotherapy on the basis of brain irradiation].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20010301

• Low infectious morbidity after intensive chemotherapy and autologous peripheral blood progenitor cell transplantation in the outpatient setting for women with breast cancer.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010215

• Incidence, cost, and outcomes of bleeding and chemotherapy dose modification among solid tumor patients with chemotherapy-induced thrombocytopenia.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010215

• A 2-step comprehensive high-dose chemoradiotherapy second-line program for relapsed and refractory Hodgkin disease: analysis by intent to treat and development of a prognostic model.

  Blood 20010201

• Stability of carmustine in polyvinyl chloride bags and polyethylene-lined trilayer plastic containers.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20010201

• Thresholds of O6-alkylguanine-DNA alkyltransferase which confer significant resistance of human glial tumor xenografts to treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea or temozolomide.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20010201

• Induction therapy of adult acute lymphocytic leukemia without the use of vincristine or prednisone.

  Hematology/oncology clinics of North America 20010201

• Current treatment of Cutaneous T-Cell Lymphoma.

  Dermatology online journal 20010201

• Incidence of post transplant myelodysplasia/acute leukemia in non-Hodgkin's lymphoma patients compared with Hodgkin's disease patients undergoing autologous transplantation following cyclophosphamide, carmustine, and etoposide (CBV).

  Leukemia & lymphoma 20010201

• Detecting treatment-by-centre interaction in multi-centre clinical trials.

  Statistics in medicine 20010130

• Standard chemotherapy with or without high-dose chemotherapy for aggressive non-Hodgkin's lymphoma: randomized phase III EORTC study.

  Journal of the National Cancer Institute 20010103

• Comparison of vincristine, carmustine, melphalan, cyclophosphamide, prednisone (VBMCP) and interferon-alpha with melphalan and prednisone (MP) and interferon-alpha (IFN-alpha) in patients with good-prognosis multiple myeloma: a prospective randomized study. Greek Myeloma Study Group.

  European journal of haematology 20010101

• Long-term results of a phase-II-pilot trial on preoperative high-dose chemotherapy with stem cell rescue in patients with cancer of the upper gastrointestinal tract.

  Oncology reports 20010101

• High-dose therapy and autologous hematopoietic cell transplantation in children with primary refractory and relapsed Hodgkin's disease: atopy predicts idiopathic diffuse lung injury syndromes.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20010101

• Anticancer drug-induced kidney disorders.

  Drug safety 20010101

• High-dose chemotherapy with bone marrow rescue for high-grade gliomas in adults.

  Cancer investigation 20010101

• Antitumor efficacy of SarCNU in a human glioma xenograft model expressing both MGMT and extraneuronal monoamine transporter.

  Journal of neuro-oncology 20010101

• Effects of carmustine on aminofluorene-DNA adducts formation in rat glial tumor cells.

  Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi 20010101

• Bendamustine.

  Drugs 20010101

• Inhaled steroids as prophylaxis for delayed pulmonary toxicity syndrome in breast cancer patients undergoing high-dose chemotherapy and autologous stem cell transplantation.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20010101

• High-dose therapy and autologous hematopoietic-cell transplantation for follicular lymphoma beyond first remission: the Stanford University experience.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20010101

• [Intracytoplasmic crystals and Fanconi syndrome in a patient with IgA kappa myeloma].

  Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20010101

• Gamma-glutamyl transferase expression in higher-grade astrocytic glioma.

  Acta oncologica (Stockholm, Sweden) 20010101

• Idiotype vaccination following ABMT can stimulate specific anti-idiotype immune responses in patients with B-cell lymphoma.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20010101

• Efficacy and toxicity of a CCNU-containing high-dose chemotherapy regimen followed by autologous hematopoietic cell transplantation in relapsed or refractory Hodgkin's disease.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20010101

• Communication challenges in a young man with Hodgkin's disease.

  Cancer practice 20010101

• Increased conventional chemotherapy does not improve survival in multiple myeloma: long-term results of two PETHEMA trials including 914 patients.

  The hematology journal : the official journal of the European Haematology Association 20010101

• Allogeneic stem-cell transplantation for lymphoproliferative disorders using BEAM-CAMPATH (+/- fludarabine) conditioning combined with post-transplant donor-lymphocyte infusion.

  Cytotherapy 20010101

• Effect of O6-benzylguanine on alkylating agent-induced toxicity and mutagenicity. In Chinese hamster ovary cells expressing wild-type and mutant O6-alkylguanine-DNA alkyltransferases.

  Cancer research 20001001

• Bilateral blindness and lumbosacral myelopathy associated with high-dose carmustine and cisplatin therapy.

  American journal of ophthalmology 20000901

• Glutathione oxidation and PTPase inhibition by hydrogen peroxide in Caco-2 cell monolayer.

  American journal of physiology. Gastrointestinal and liver physiology 20000801

• High-dose carmustine, thiotepa and etoposide followed by autologous bone marrow rescue for the treatment of high risk central nervous system tumors.

  Bone marrow transplantation 20000701

• Cardiac sequelae of doxorubicin and paclitaxel as induction chemotherapy prior to high-dose chemotherapy and peripheral blood progenitor cell transplantation in women with high-risk primary or metastatic breast cancer.

  Bone marrow transplantation 20000501

• The role of autologous transplantation in patients with multiple myeloma aged 65 years and over.

  Bone marrow transplantation 20000301

• Tumor bed cyst formation after BCNU wafer implantation: report of two cases.

  Surgical neurology 20000301

• A sequential chemo-radiotherapeutic treatment for patients with malignant gliomas: a phase II pilot study.

  Anticancer research 20000101

• Carboxypeptidase G2 rescue in a 79 year-old patient with cranial lymphoma after high-dose methotrexate induced acute renal failure.

  Leukemia & lymphoma 19991101

• Primary Central Nervous System Tumors in Adults.

  Current treatment options in neurology 19991101

• Cytoprotective effects of trimetazidine in carmustine cholestasis.

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 19990701

• Increase of BCNU sensitivity by wt-p53 gene therapy in glioblastoma lines depends on the administration schedule.

  Gene therapy 19990601

• Acute encephalopathy: a new toxicity associated with high-dose paclitaxel.

  Clinical cancer research : an official journal of the American Association for Cancer Research 19990301

• Tetrazepinones are equally cytotoxic to Mer+ and Mer- human tumor cell lines.

  The Journal of pharmacology and experimental therapeutics 19990201

• Genetic effects of exocyclic DNA adducts in vivo: heritable genetic damage in comparison with loss of heterozygosity in somatic cells.

  IARC scientific publications 19990101

• Treatment of supratentorial glioblastoma multiforme with radiotherapy and a combination of BCNU and tamoxifen: a phase II study.

  Journal of neuro-oncology 19990101

• Synchronous radiochemotherapy in unfavorable brain tumors of children and young adults.

  Journal of neuro-oncology 19980801

• White matter disease induced by high-dose chemotherapy: longitudinal study with MR imaging and proton spectroscopy.

  AJNR. American journal of neuroradiology 19980201

• Navoban (tropisetron, ICS 205-930) and dexamethasone combination in the prevention of vomiting for patients receiving preconditioning high-dose chemotherapy before marrow transplantation.

  Japanese journal of clinical oncology 19980201

• Headache, circumoral paresthesia, and facial flushing associated with high-dose carmustine infusion.

  Bone marrow transplantation 19970401

• Conformational change in human DNA repair enzyme O6-methylguanine-DNA methyltransferase upon alkylation of its active site by SN1 (indirect-acting) and SN2 (direct-acting) alkylating agents: breaking a 'salt-link'.

  Biochemistry 19960924

• Inhibition of cell growth and sensitization to oxidative damage by overexpression of manganese superoxide dismutase in rat glioma cells.

  Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 19960901

• Regulation of hepatic nitric oxide synthase by reactive oxygen intermediates and glutathione.

  Archives of biochemistry and biophysics 19950201

• In vivo enhanced antitumor activity of carmustine [N,N'-bis(2-chloroethyl)-N-nitrosourea] by simvastatin.

  Cancer research 19950201

• Visual hallucinations following treatment with vincristine.

  Clinical and laboratory haematology 19941201

• Phase I trial of dacarbazine with cyclophosphamide, carmustine, etoposide, and autologous stem-cell transplantation in patients with lymphoma and multiple myeloma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19940901

• FIVB plus GM-CSF in metastatic colorectal cancer.

  Investigational new drugs 19940101

• Decrease in penbutolol protein binding as a consequence of treatment with some alkylating agents.

  Cancer chemotherapy and pharmacology 19940101

• Contribution of glutathione transferase M3-3 to 1,3-bis(2-chloroethyl)-1-nitrosourea resistance in a human non-small cell lung cancer cell line.

  Cancer research 19930915

• Pentostatin increases the acute toxicity of high dose cyclophosphamide.

  Bone marrow transplantation 19930901

• The chemohormonal therapy of metastatic melanoma: possible benefit of tamoxifen.

  The West Virginia medical journal 19930601

• Cisplatin-CBV with autologous bone marrow transplantation for relapsed Hodgkin's disease.

  Leukemia & lymphoma 19930101

• Combined intra-arterial and systemic chemotherapy for recurrent malignant brain tumors.

  Neurosurgery 19920201

• Treatment of melphalan-resistant multiple myeloma with vincristine, BCNU, doxorubicin, and high-dose dexamethasone (VBAD).

  European journal of cancer (Oxford, England : 1990) 19920101

• Myocardial ischemia associated with high-dose carmustine infusion.

  Cancer 19911101

• Mouse bronchiolar cell carcinogenesis. Histologic characterization and expression of Clara cell antigen in lesions induced by N-nitrosobis-(2-chloroethyl) ureas.

  The American journal of pathology 19910801

• Neurotoxicity after intracarotid 1,3-bis(2-chloroethyl)-1-nitrosourea administration in the rat: hemodynamic changes studied by double-tracer autoradiography.

  Neurosurgery 19910701

• Increased paracellular permeability in intrahepatic cholestasis induced by carmustine (BCNU) in rats.

  Gastroenterology 19910701

• Defenses against oxidation in human erythrocytes: role of glutathione reductase in the activation of glucose decarboxylation by hemolytic drugs.

  The Journal of laboratory and clinical medicine 19910401

• Combined intra-arterial chemotherapy and irradiation of malignant gliomas.

  Acta oncologica (Stockholm, Sweden) 19910101

• Glutathione-dependent detoxification of peroxide in bovine ciliary body.

  Experimental eye research 19900601

• A novel lung slice system with compromised antioxidant defenses.

  Environmental health perspectives 19900401

• The effect of 1,3 bis-(2-chloroethyl)-1-nitrosourea on rat brain glutathione status under conditions of normoxia and hyperoxia.

  Research communications in chemical pathology and pharmacology 19900301

• High-dose carboplatin, cyclophosphamide, and BCNU with autologous bone marrow support: excessive hepatic toxicity.

  Cancer chemotherapy and pharmacology 19900101

• Immunomodulation by various nitrosoureas and its effect on the survival of the murine host bearing a syngeneic tumor.

  Cancer research 19891201

• The importance of tamoxifen to a cisplatin-containing regimen in the treatment of metastatic melanoma.

  Cancer 19890401

• Oxidative cell injury in the killing of cultured hepatocytes by allyl alcohol.

  Archives of biochemistry and biophysics 19880901

• Pre-irradiation internal carotid artery BCNU in treatment of glioblastoma multiforme.

  Journal of neurosurgery 19880601

• Visual system toxicity following intra-arterial chemotherapy.

  Neurology 19880201

• Pulmonary veno-occlusive disease following therapy for malignant neoplasms.

  Chest 19871101

• Ischemic optic neuropathy secondary to intracarotid infusion of BCNU.

  Journal of clinical neuro-ophthalmology 19870601

• High-dose carmustine with autologous bone marrow transplantation for the adjuvant treatment of high-grade gliomas of the central nervous system.

  Cancer treatment reports 19870201

• Neurological deficit after carotid infusion of cisplatin and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) for malignant glioma: an analysis of risk factors.

  Neurosurgery 19861101

• Prevention of ocular toxicity of carmustine (BCNU) with supraophthalmic intracarotid infusion.

  Ophthalmology 19861101

• Intracarotid BCNU leukoencephalopathy.

  Cancer 19860401

• Effects of oxidative stress caused by hyperoxia and diquat. A study in isolated hepatocytes.

  Free radical research communications 19860101

• Central neurotoxicity following intracarotid BCNU chemotherapy for malignant gliomas.

  Journal of neuro-oncology 19860101

• Melphalan-resistant multiple myeloma: results of treatment according to the M-2 protocol.

  Cancer chemotherapy and pharmacology 19850101

• BCVPP chemotherapy for advanced Hodgkin's disease: evidence for greater duration of complete remission, greater survival, and less toxicity than with a MOPP regimen. Results of the Eastern Cooperative Oncology Group study.

  Annals of internal medicine 19841001

• Intra-arterial BCNU chemotherapy for treatment of malignant gliomas of the central nervous system.

  Journal of neurosurgery 19840901

• Malignant anorexia after nitrosourea therapy: case report.

  Neurosurgery 19840401

• Neurological complications of antineoplastic therapy.

  Acta neurologica Scandinavica. Supplementum 19840101

• Orbital angiographic changes after intracarotid BCNU chemotherapy.

  AJNR. American journal of neuroradiology 19840101

• Intensive 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), NSC #4366650 and cryopreserved autologous marrow transplantation for refractory cancer. A phase I-II study.

  Cancer 19831115

• Hemorrhagic cystitis after low-dose cyclophosphamide.

  Lancet (London, England) 19830528

• Disseminated intravascular coagulation--a complication of 1,3-bis(2-chlorethyl)-nitrosourea therapy.

  Surgical neurology 19830201

• Improved regional selectivity of hepatic arterial BCNU with degradable microspheres.

  Cancer 19820815

• Enhancement by electron-affinic agents of the therapeutic effects of cytotoxic agents against the KHT tumor: structure-activity relationships.

  International journal of radiation oncology, biology, physics 19820101

• Ophthalmic and central nervous system complications following intracarotid BCNU (Carmustine).

  Journal of clinical neuro-ophthalmology 19811201

• Nephrotoxicity of nitrosoureas.

  Cancer 19810915

• Intra-arterial BCNU chemotherapy for the treatment of malignant gliomas of the central nervous system: a preliminary report.

  Cancer treatment reports 19810101

• Intra-arterial BCNU therapy in the treatment of metastatic brain tumor from lung carcinoma: a preliminary report.

  Cancer 19791201

• Hepatocellular carcinoma in a young woman with prolonged exposure to oral contraceptives.

  Medical and pediatric oncology 19780101

• Optic neuroretinitis in association with BCNU and procarbazine therapy.

  Medical and pediatric oncology 19780101

• [Kinetic study of the effect of N-nitroso-N-alkylurea on the development of leukemia L1210].

  Voprosy onkologii 19770101

• Single-agent chemotherapy of brain tumors. A five-year review.

  Archives of neurology 19761101

• Chemotherapeutic effects of some alkylating derivatives of nitrosourea on the development of tumors transplacentally induced in rats by ENU.

  Acta neuropathologica 19760131

• Necrotizing encephalopathy following intraventricular instillation of methotrexate.

  Archives of neurology 19730201

• The chemotherapy of brain tumors. Clinical experience with carmustine (BCNU) and vincristine.

  JAMA 19721030