15622-65-8 | Molindone hydrochloride

Packsize	Purity	Availability	Price	Discounted Price
10mg	98%	in stock	$15.00	$10.00
25mg	98%	in stock	$18.00	$12.00
50mg	98%	in stock	$22.00	$15.00
1g	98%	in stock	$32.00	$22.00
5g	98%	in stock	$73.00	$51.00
25g	98%	in stock	$258.00	$180.00

Description

• Catalog Number: AA78356
• Chemical Name: Molindone hydrochloride
• CAS Number: 15622-65-8
• Molecular Formula: C16H25ClN2O2
• Molecular Weight: 312.8349
• MDL Number: MFCD01718304
• SMILES: CCc1c(C)[nH]c2c1C(=O)C(CC2)CN1CCOCC1.Cl

Computed Properties

• Complexity: 354
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 21
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 3
• Undefined Atom Stereocenter Count: 1

Literature

• Reversibility of dopamine receptor antagonist-induced hyperprolactinemia and associated histological changes in Tg RasH2 wild-type mice.

  Reproductive toxicology (Elmsford, N.Y.) 20151201

• Neurocognitive outcomes in the Treatment of Early-Onset Schizophrenia Spectrum Disorders study.

  Journal of the American Academy of Child and Adolescent Psychiatry 20120501

• A phase 2a randomized, parallel group, dose-ranging study of molindone in children with attention-deficit/hyperactivity disorder and persistent, serious conduct problems.

  Journal of child and adolescent psychopharmacology 20120401

• A predictive ligand-based Bayesian model for human drug-induced liver injury.

  Drug metabolism and disposition: the biological fate of chemicals 20101201

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Double-blind maintenance safety and effectiveness findings from the Treatment of Early-Onset Schizophrenia Spectrum (TEOSS) study.

  Journal of the American Academy of Child and Adolescent Psychiatry 20100601

• Treatment of morbidly obese psychotic patients with molindone: three case reports.

  The Journal of clinical psychiatry 20091101

• Potential lower efficacy of molindone among first-generation antipsychotics.

  The American journal of psychiatry 20090401

• Aripiprazole-induced agitation after clozapine discontinuation: a case report.

  The Journal of clinical psychiatry 20090101

• Double-blind comparison of first- and second-generation antipsychotics in early-onset schizophrenia and schizo-affective disorder: findings from the treatment of early-onset schizophrenia spectrum disorders (TEOSS) study.

  The American journal of psychiatry 20081101

• Efficacy of molindone in treatment-refractory agitated schizophrenia: three case reports.

  The Journal of clinical psychiatry 20080601

• Determination of molindone enantiomers in human plasma by high-performance liquid chromatography-tandem mass spectrometry using macrocyclic antibiotic chiral stationary phases.

  Journal of chromatography. A 20080530

• Treatment of early-onset schizophrenia spectrum disorders (TEOSS): rationale, design, and methods.

  Journal of the American Academy of Child and Adolescent Psychiatry 20070801

• Molindone for schizophrenia and severe mental illness.

  The Cochrane database of systematic reviews 20070124

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Glutamatergic drugs for schizophrenia: a systematic review and meta-analysis.

  Schizophrenia research 20050101

• Neuroacanthocytosis.

  The American journal of psychiatry 20040901

• Tissue distribution of molidone in a multidrug overdose.

  Journal of analytical toxicology 20040901

• Paroxetine-molindone interaction.

  The Journal of clinical psychiatry 19950201

• Neuroleptic malignant syndrome possibly caused by molindone hydrochloride.

  DICP : the annals of pharmacotherapy 19911001

• Neuroleptic-induced 'painful legs and moving toes' syndrome: successful treatment with clonazepam and baclofen.

  Italian journal of neurological sciences 19901201

• Polydipsia and hyponatremia induced by multiple neuroleptics but not molindone.

  Canadian journal of psychiatry. Revue canadienne de psychiatrie 19900401

• Relation of serum molindone levels to serum prolactin levels and antipsychotic response.

  The Journal of clinical psychiatry 19891001

• D-1 and D-2 receptor blockade have additive cataleptic effects in mice, but receptor effects may interact in opposite ways.

  Pharmacology, biochemistry, and behavior 19880201

• A case of massive rhabdomyolysis following molindone administration.

  The Journal of clinical psychiatry 19861201

• Molindone hydrochloride treatment of hospitalized children with conduct disorder.

  The Journal of clinical psychiatry 19850801

• Clinical experience with molindone hydrochloride in geriatric patients.

  The Journal of clinical psychiatry 19850801

• Drug interactions on spontaneous locomotor activity in rats. Neuroleptics and amphetamine-induced hyperactivity.

  Neuropharmacology 19840801

• Effect of alpha-methyl-p-tyrosine on neuroleptic-induced catalepsy in rat.

  Indian journal of physiology and pharmacology 19830101

• Bromocriptine associated with symptom exacerbation during neuroleptic treatment of schizoaffective schizophrenia.

  The Journal of clinical psychiatry 19820601

• Neuroleptic-induced seizures. An in vitro technique for assessing relative risk.

  Archives of general psychiatry 19820201

• Dystonic reaction during maintenance antipsychotic therapy.

  The American journal of psychiatry 19810101