15761-38-3 | Boc-Ala-OH

Packsize	Purity	Availability	Price	Discounted Price
10g	98%	in stock	$6.00	$4.00
25g	98%	in stock	$6.00	$5.00
100g	98%	in stock	$10.00	$7.00
250g	98%	in stock	$23.00	$16.00
500g	98%	in stock	$39.00	$27.00
1000g	98%	in stock	$75.00	$53.00

Description

• Catalog Number: AI37607
• Chemical Name: Boc-Ala-OH
• CAS Number: 15761-38-3
• Molecular Formula: C8H15NO4
• Molecular Weight: 189.209
• MDL Number: MFCD00037225
• SMILES: C[C@@H](C(=O)O)NC(=O)OC(C)(C)C

Computed Properties

• Complexity: 207
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 4
• XLogP3: 0.9

Upstream Synthesis Route

N-(tert-Butoxycarbonyl)-L-alanine, also known as Boc-L-alanine, is a versatile compound commonly used in chemical synthesis. Its application lies in peptide synthesis, where it acts as a protecting group for the amine functional group of amino acids. By temporarily masking the reactive amine group with the Boc protecting group, chemists can selectively manipulate other functional groups without affecting the desired amine functionality. This methodology enables the sequential and controlled assembly of complex peptides and proteins, making Boc-L-alanine a valuable tool in the field of organic chemistry.

Literature

• Microspheres consisting of optically active helical substituted polyacetylenes: preparation via suspension polymerization and their chiral recognition/release properties.

  Macromolecular rapid communications 20111215

• Practical syntheses of a CXCR3 antagonist.

  The Journal of organic chemistry 20110318

• Facile synthesis of multiamino vinyl poly(amino acid)s for promising bioapplications.

  Biomacromolecules 20101213

• Solvent-directed self-assembly of pi gelators to hierarchical macroporous structures and aligned fiber bundles.

  Chemistry, an Asian journal 20090602

• 4'-Epidoxorubicin to re-explore anthracycline degradation in cardiomyocytes.

  Chemical research in toxicology 20090601

• 'Naked-eye' enantioselective chemosensors for N-protected amino acid anions bearing thiourea units.

  Chirality 20090301

• Imidazolium-functionalized BINOL as a multifunctional receptor for chromogenic and chiral anion recognition.

  Organic letters 20090205

• Anthracene derivatives bearing thiourea and glucopyranosyl groups for the highly selective chiral recognition of amino acids: opposite chiral selectivities from similar binding units.

  The Journal of organic chemistry 20080104

• Doxorubicin degradation in cardiomyocytes.

  The Journal of pharmacology and experimental therapeutics 20070701

• Highly enantioselective ruthenium-catalyzed reduction of ketones employing readily available Peptide ligands.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20040105

• Employing the structural diversity of nature: development of modular dipeptide-analogue ligands for ruthenium-catalyzed enantioselective transfer hydrogenation of ketones.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20030905

• Molecular discrimination of N-protected amino acid esters by a self-assembled cylindrical capsule: spectroscopic and computational studies.

  The Journal of organic chemistry 20021129