15788-16-6 | 1H-Benzimidazole-5-carboxylic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$13.00	$9.00
5g	97%	in stock	$16.00	$11.00
10g	97%	in stock	$22.00	$16.00
25g	97%	in stock	$39.00	$27.00
100g	97%	in stock	$152.00	$106.00
500g	97%	in stock	$727.00	$509.00

Description

• Catalog Number: AA79896
• Chemical Name: 1H-Benzimidazole-5-carboxylic acid
• CAS Number: 15788-16-6
• Molecular Formula: C8H6N2O2
• Molecular Weight: 162.1454
• MDL Number: MFCD00011555
• SMILES: OC(=O)c1ccc2c(c1)[nH]cn2

Computed Properties

• Complexity: 196
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 1.3

Literature

• Fragment-based design of symmetrical bis-benzimidazoles as selective inhibitors of the trimethoprim-resistant, type II R67 dihydrofolate reductase.

  Journal of medicinal chemistry 20120412

• Ethyl 1-(2-hy-droxy-eth-yl)-2-propyl-1H-benzimidazole-5-carboxyl-ate.

  Acta crystallographica. Section E, Structure reports online 20111001

• Poly[μ-aqua-diaqua(μ(3)-1H-benzimid-azole-5-carboxylato-κN:O,O')(μ(2)-1H-benzimidazole-5-carboxylato-κN:O:O')-μ(5)-sulfato-μ(4)-sulfato-tri-cadmium].

  Acta crystallographica. Section E, Structure reports online 20110901

• Development of imidazole alkanoic acids as mGAT3 selective GABA uptake inhibitors.

  European journal of medicinal chemistry 20110501

• Flexible and asymmetric ligand in constructing coordinated complexes: synthesis, crystal structures and fluorescent characterization.

  International journal of molecular sciences 20110101

• Synthesis and antitumor activity of novel benzimidazole-5-carboxylic acid derivatives and their transition metal complexes as topoisomerease II inhibitors.

  European journal of medicinal chemistry 20101201

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• 1-(5-Carboxyindol-1-yl)propan-2-ones as inhibitors of human cytosolic phospholipase A2alpha: synthesis and properties of bioisosteric benzimidazole, benzotriazole and indazole analogues.

  Bioorganic & medicinal chemistry letters 20090415

• New transition metal ion complexes with benzimidazole-5-carboxylic acid hydrazides with antitumor activity.

  European journal of medicinal chemistry 20090401

• Discovery, SAR and X-ray structure of 1H-benzimidazole-5-carboxylic acid cyclohexyl-methyl-amides as inhibitors of inducible T-cell kinase (Itk).

  Bioorganic & medicinal chemistry letters 20081015

• Double fluorescence conversion in ultraviolet and visible region for some praseodymium complexes of aromatic carboxylates.

  Journal of fluorescence 20060701

• Synthesis and potent antimicrobial activity of some novel methyl or ethyl 1H-benzimidazole-5-carboxylates derivatives carrying amide or amidine groups.

  Bioorganic & medicinal chemistry 20050301

• Methods for generation of monoclonal antibodies to the very small drug hapten, 5-benzimidazolecarboxylic acid.

  Journal of immunological methods 20021220