158063-66-2 | 4-(Trifluoromethyl)nicotinic acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$6.00	$4.00
1g	97%	in stock	$8.00	$5.00
5g	97%	in stock	$10.00	$7.00
25g	97%	in stock	$27.00	$19.00
100g	97%	in stock	$75.00	$52.00
500g	97%	in stock	$299.00	$209.00

Description

• Catalog Number: AA80074
• Chemical Name: 4-(Trifluoromethyl)nicotinic acid
• CAS Number: 158063-66-2
• Molecular Formula: C7H4F3NO2
• Molecular Weight: 191.1074
• MDL Number: MFCD00082626
• SMILES: OC(=O)c1cnccc1C(F)(F)F

Computed Properties

• Complexity: 204
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 1.3

Upstream Synthesis Route

4-(Trifluoromethyl)Nicotinic Acid is a versatile and valuable compound widely used in chemical synthesis. It serves as a key building block in the creation of various pharmaceuticals, agrochemicals, and functional materials. With its unique trifluoromethyl group, this compound imparts special properties such as increased lipophilicity, bioavailability, and metabolic stability to the molecules it is incorporated into.In organic synthesis, 4-(Trifluoromethyl)Nicotinic Acid is often employed as a precursor for the synthesis of a wide array of structurally diverse compounds. It can undergo various transformations including cross-coupling reactions, nucleophilic additions, and cyclizations to introduce the trifluoromethyl group into target molecules. This allows for the modification of chemical structures to enhance desired properties or create new functionalities.The use of 4-(Trifluoromethyl)Nicotinic Acid in chemical synthesis enables chemists to access complex molecules with improved biological activities, making it a valuable tool in drug discovery and development. Its versatile nature and ability to introduce unique functionalities make it a sought-after building block in the field of organic chemistry.

Literature

• [Simultaneous determination of flonicamid and its metabolites in cucumbers and apples by liquid chromatography-tandem mass spectrometry].

  Se pu = Chinese journal of chromatography 20120601

• Simultaneous determination of flonicamid and its metabolites in vegetables using QuEChERS and reverse-phase liquid chromatography-tandem mass spectrometry.

  Journal of chromatography. A 20110923