15876-67-2 | Distigmine bromide

Packsize	Purity	Availability	Price	Discounted Price
10mg	96%	in stock	$154.00	$108.00
100mg	96%	in stock	$235.00	$165.00
250mg	96%	in stock	$372.00	$260.00
1g	96%	in stock	$946.00	$662.00

Description

• Catalog Number: AA81241
• Chemical Name: Distigmine bromide
• CAS Number: 15876-67-2
• Molecular Formula: C22H32Br2N4O4
• Molecular Weight: 576.3219
• MDL Number: MFCD00867188
• SMILES: C[n+]1cccc(c1)OC(=O)N(CCCCCCN(C(=O)Oc1ccc[n+](c1)C)C)C.[Br-].[Br-]

Computed Properties

• Complexity: 487
• Covalently-Bonded Unit Count: 3
• Heavy Atom Count: 32
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 11

Literature

• Cholinergic drugs for treatment of recurrent urinary retention in high surgical risk/elderly BPH patients. A pilot study.

  Minerva urologica e nefrologica = The Italian journal of urology and nephrology 20120901

• Effect of distigmine combined with propiverine on bladder activity in rats with spinal cord injury.

  International journal of urology : official journal of the Japanese Urological Association 20120501

• Effects of a peripheral cholinesterase inhibitor on cytokine production and autonomic nervous activity in a rat model of sepsis.

  Cytokine 20120201

• [Acute respiratory failure associated with cholinergic crisis: report of five cases and review of the literature].

  Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20111201

• [Establishing indicators for diagnosis of cholinergic crisis].

  Rinsho byori. The Japanese journal of clinical pathology 20101001

• Demonstration of muscarinic and nicotinic receptor binding activities of distigmine to treat detrusor underactivity.

  Biological & pharmaceutical bulletin 20100101

• Pharmacokinetic and pharmacodynamic analysis of acetylcholinesterase inhibition by distigmine bromide in rats.

  Drug metabolism and pharmacokinetics 20100101

• Effect of distigmine bromide on the central cholinergic system.

  Journal of psychopharmacology (Oxford, England) 20090301

• [Treatment approach to congenital myasthenic syndrome in a patient with acetylcholine receptor deficiency].

  No to hattatsu = Brain and development 20090101

• [Acute poisoning due to distigmine bromide].

  Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology 20080401

• [Three cases of cholinergic crisis in which serum distigmine bromide concentrations were measured].

  Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology 20080101

• Nocturnal hypersalivation caused by distigmine bromide in a patient with multiple system atrophy.

  Internal medicine (Tokyo, Japan) 20080101

• Ubretid (distigmine bromide) taken to treat urinary retention prolongs the effect of suxamethonium.

  Journal of anesthesia 20080101

• Screening procedure for the analysis of distigmine bromide in serum by high-performance liquid chromatography-electrospray ionization mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070601

• [Distigmine bromide improves chronic intestinal pseudo-obstruction in a case of MELAS].

  Rinsho shinkeigaku = Clinical neurology 20070401

• Effects of the selective acetylcholinesterase inhibitor TAK-802 on the voiding behavior and bladder mass increase in rats with partial bladder outlet obstruction.

  The Journal of urology 20050901

• [Distigmine bromide induced Parkinsonism. A case report].

  Rinsho shinkeigaku = Clinical neurology 20050801

• [A case of acute distigmine bromide intoxication in the therapeutic dosage for treatment of underactive neurogenic bladder].

  No to shinkei = Brain and nerve 20040501

• Combination of a cholinergic drug and an alpha-blocker is more effective than monotherapy for the treatment of voiding difficulty in patients with underactive detrusor.

  International journal of urology : official journal of the Japanese Urological Association 20040201

• Clinical efficacy of distigmine bromide in the treatment of patients with underactive detrusor.

  International urology and nephrology 20040101

• Rhabdomyolysis caused by distigmine bromide.

  Internal medicine (Tokyo, Japan) 20031101

• Distigmine bromide induced acute psychotic disorder in a patient with multiple sclerosis.

  European psychiatry : the journal of the Association of European Psychiatrists 20031001

• [Cholinergic crisis following administration of distigmine bromide: a case report].

  Hinyokika kiyo. Acta urologica Japonica 20020101

• Symptomatic and urodynamic improvement by oral distigmine bromide in poor voiders after transurethral resection of the prostate.

  Urology 20010201