158816-55-8 | 3,4,5-Trifluorophenylacetylene

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$12.00	$9.00
1g	95%	in stock	$39.00	$28.00
5g	95%	in stock	$152.00	$106.00
100g	95%	in stock	$1,879.00	$1,316.00

Description

• Catalog Number: AB53570
• Chemical Name: 3,4,5-Trifluorophenylacetylene
• CAS Number: 158816-55-8
• Molecular Formula: C8H3F3
• Molecular Weight: 156.1046
• MDL Number: MFCD08458177
• SMILES: C#Cc1cc(F)c(c(c1)F)F

Computed Properties

• Complexity: 169
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• XLogP3: 2.5

Upstream Synthesis Route

3,4,5-Trifluorophenylacetylene, also known as $name$, is a versatile compound commonly used in chemical synthesis for its unique properties and reactivity. Due to the presence of three fluorine atoms on the phenyl ring, this compound exhibits enhanced electron-withdrawing effects, making it an excellent building block for various synthetic transformations.One key application of 3,4,5-Trifluorophenylacetylene is in the synthesis of aryl-substituted alkynes. The presence of the acetylene group allows for further functionalization through various coupling reactions such as Sonogashira, Heck, or cross-coupling reactions. This compound serves as an important intermediate in the preparation of complex organic molecules and pharmaceuticals.Moreover, 3,4,5-Trifluorophenylacetylene can also be employed in the construction of fluorinated organic compounds. The trifluorophenyl group imparts unique electronic and steric properties to the molecules, which can be beneficial in designing materials with specific properties such as increased stability, bioavailability, or optical properties.Additionally, the reactivity of 3,4,5-Trifluorophenylacetylene makes it a valuable reagent for the synthesis of heterocyclic compounds and natural products. Its ability to undergo various transformations under mild conditions makes it highly sought after in the field of organic chemistry for the preparation of diverse molecular structures.In conclusion, 3,4,5-Trifluorophenylacetylene plays a crucial role in chemical synthesis, offering researchers a versatile tool for the construction of complex molecules with tailored properties and functionalities. Its unique characteristics make it a valuable asset in the arsenal of synthetic chemists aiming to develop innovative materials and pharmaceuticals.