160809-34-7 | benzyl 4-acetylpiperidine-1-carboxylate

Packsize	Purity	Availability	Price	Discounted Price
250mg	96%	in stock	$139.00	$97.00
1g	96%	in stock	$325.00	$228.00
5g	96%	in stock	$946.00	$662.00
25g	96%	in stock	$2,811.00	$1,968.00
100g	96%	in stock	$7,474.00	$5,232.00

Description

• Catalog Number: AE96973
• Chemical Name: benzyl 4-acetylpiperidine-1-carboxylate
• CAS Number: 160809-34-7
• Molecular Formula: C15H19NO3
• Molecular Weight: 261.3163
• MDL Number: MFCD09953370
• SMILES: O=C(N1CCC(CC1)C(=O)C)OCc1ccccc1

Upstream Synthesis Route

To synthesize benzyl 4-acetylpiperidine-1-carboxylate, one could pursue the following upstream synthesis route:

1. **Acetylation of 4-Piperidone**: Begin with 4-piperidone monohydrate, undergoing an acetylation reaction using acetic anhydride to introduce the acetyl group, yielding 4-acetylpiperidine.

2. **Benzyl Ester Formation**: Next, perform an esterification of the carboxylic acid formed in step one using benzyl alcohol. The reaction typically employs a strong acid catalyst such as sulfuric acid or hydrochloric acid under reflux conditions, forming benzyl 4-acetylpiperidine-1-carboxylate.

3. **Purification**: Finally, purify the product using appropriate chromatographic techniques or recrystallization, if necessary, to ensure the removal of any byproducts or unreacted starting materials.

This synthesis route is particularly efficient due to the use of readily available starting materials and straightforward reactions that proceed under relatively mild conditions.