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Silodosin : a new subtype selective alpha-1 antagonist for the treatment of lower urinary tract symptoms in patients with benign prostatic hyperplasia.
Expert opinion on pharmacotherapy 20121001
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Benign prostatic hyperplasia (BPH) management in the primary care setting.
The Canadian journal of urology 20121001
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Emerging therapies: what's new is old and what's old is new.
The Canadian journal of urology 20121001
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Effects of tamsulosin and silodosin on isolated albino and pigmented rabbit iris dilators: possible mechanism of intraoperative floppy-iris syndrome.
Journal of cataract and refractive surgery 20120901
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Re: Naftopidil vs silodosin in medical expulsive therapy for ureteral stones: a randomized controlled study in Japanese male patients.
International journal of urology : official journal of the Japanese Urological Association 20120801
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Comparison of the effects of four α1-adrenoceptor antagonists on ejaculatory function in rats.
Urology 20120801
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Effect of silodosin on detrusor overactivity in the male spontaneously hypertensive rat.
BJU international 20120701
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Excitatory effect of propiverine hydrochloride on urethral activity in rats.
International journal of urology : official journal of the Japanese Urological Association 20120601
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Re: silodosin therapy for lower urinary tract symptoms in men with suspected benign prostatic hyperplasia: results of an international, randomized, double-blind, placebo- and active-controlled clinical trial performed in Europe.
The Journal of urology 20120501
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Silodosin: erectile and ejaculatory disorders.
Prescrire international 20120501
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Prescriber monitoring for benign prostatic hyperplasia within a family medicine clinic: a comparison of medication classes.
Journal of pharmacy practice 20120401
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New clinical evidence of silodosin, an α(1A) selective adrenoceptor antagonist, in the treatment for lower urinary tract symptoms.
International journal of urology : official journal of the Japanese Urological Association 20120401
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Effects of α1-adrenoceptor antagonists on phenylephrine-induced salivary secretion and intraurethral pressure elevation in anesthetized rats.
European journal of pharmacology 20120315
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Silodosin and its potential for treating premature ejaculation: a preliminary report.
International journal of urology : official journal of the Japanese Urological Association 20120301
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Benign prostatic hyperplasia: from bench to clinic.
Korean journal of urology 20120301
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α-Blockers for benign prostatic hyperplasia: the new era.
Current opinion in urology 20120101
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Tamsulosin potently and selectively antagonizes human recombinant α(1A/1D)-adrenoceptors: slow dissociation from the α(1A)-adrenoceptor may account for selectivity for α(1A)-adrenoceptor over α(1B)-adrenoceptor subtype.
Biological & pharmaceutical bulletin 20120101
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Non-inferiority of silodosin to tamsulosin in treating patients with lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH).
BJU international 20111201
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Comparison of prophylactic naftopidil, tamsulosin, and silodosin for 125I brachytherapy-induced lower urinary tract symptoms in patients with prostate cancer: randomized controlled trial.
International journal of radiation oncology, biology, physics 20111115
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Naftopidil vs silodosin in medical expulsive therapy for ureteral stones: a randomized controlled study in Japanese male patients.
International journal of urology : official journal of the Japanese Urological Association 20111101
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[Medical expulsive therapy facilitated by alpha 1 adrenoceptor antagonist].
Clinical calcium 20111001
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Silodosin in the treatment of the signs and symptoms of benign prostatic hyperplasia: profile report.
Drugs & aging 20111001
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Efficacy of selective α1A adrenoceptor antagonist silodosin in the medical expulsive therapy for ureteral stones.
International journal of urology : official journal of the Japanese Urological Association 20110901
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Effect of 5-alpha Reductase Inhibitor on Storage Symptoms in Patients with Benign Prostatic Hyperplasia.
International neurourology journal 20110901
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α1-Adrenoceptors and muscarinic receptors in voiding function - binding characteristics of therapeutic agents in relation to the pharmacokinetics.
British journal of clinical pharmacology 20110801
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Re: Christopher R. Chapple, Francesco Montorsi, Teuvo L.J. Tammela, et al. Silodosin therapy for lower urinary tract symptoms in men with suspected benign prostatic hyperplasia: results of an international, randomized, double-blind, placebo- and active-controlled clinical trial performed in Europe. Eur Urol 2011;59:342-52.
European urology 20110801
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Silodosin for men with chronic prostatitis/chronic pelvic pain syndrome: results of a phase II multicenter, double-blind, placebo controlled study.
The Journal of urology 20110701
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Symptomatic and urodynamic responses in patients with reduced or no seminal emission during silodosin treatment for LUTS and BPH.
Prostate cancer and prostatic diseases 20110601
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[Optimum initial dose of silodosin for treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia].
Hinyokika kiyo. Acta urologica Japonica 20110601
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Silodosin: treatment of the signs and symptoms of benign prostatic hyperplasia.
Drugs 20110507
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Alpha1-adrenoceptor antagonists improve bladder storage function through reduction of afferent activity in rats with bladder outlet obstruction.
Neurourology and urodynamics 20110301
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Silodosin therapy for lower urinary tract symptoms in men with suspected benign prostatic hyperplasia: results of an international, randomized, double-blind, placebo- and active-controlled clinical trial performed in Europe.
European urology 20110301
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Does the use of silodosin to treat benign prostatic hyperplasia really offer something new?
European urology 20110301
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Characterization of α1-adrenoceptor subtypes mediating contraction in human isolated ureters.
Urology 20110301
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Effects of three types of alpha-1 adrenoceptor blocker on lower urinary tract symptoms and sexual function in males with benign prostatic hyperplasia.
International journal of urology : official journal of the Japanese Urological Association 20110301
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Naftopidil, a selective {alpha}1-adrenoceptor antagonist, suppresses human prostate tumor growth by altering interactions between tumor cells and stroma.
Cancer prevention research (Philadelphia, Pa.) 20110101
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BHP: Silodosin an effective new drug for BPH-associated LUTS.
Nature reviews. Urology 20110101
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(RS)-1-[5-(2-Chloro-prop-yl)indolin-1-yl]ethanone.
Acta crystallographica. Section E, Structure reports online 20110101
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A randomized crossover study comparing patient preference for tamsulosin and silodosin in patients with lower urinary tract symptoms associated with benign prostatic hyperplasia.
The Journal of international medical research 20110101
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Silodosin.
Prescrire international 20110101
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Safety and efficacy of silodosin for the treatment of benign prostatic hyperplasia.
Clinical interventions in aging 20110101
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Naftopidil for the treatment of urinary symptoms in patients with benign prostatic hyperplasia.
Therapeutics and clinical risk management 20110101
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Safety and pharmacokinetic studies of silodosin, a new α1A-adrenoceptor selective antagonist, in healthy Chinese male subjects.
Biological & pharmaceutical bulletin 20110101
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Efficacy of electroacupuncture at Zhongliao point (BL33) for mild and moderate benign prostatic hyperplasia: study protocol for a randomized controlled trial.
Trials 20110101
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Ejaculation disorder is associated with increased efficacy of silodosin for benign prostatic hyperplasia.
Urology 20101201
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Silodosin for the treatment of benign prostatic hyperplasia: pharmacology and cardiovascular tolerability.
Pharmacotherapy 20101201
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Gateways to clinical trials.
Methods and findings in experimental and clinical pharmacology 20101101
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Selective α1A-blocker improves bladder storage function in rats via suppression of C-fiber afferent activity.
World journal of urology 20101001
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Role of supraspinal and spinal alpha1-adrenergic receptor subtypes in micturition reflex in conscious rats.
American journal of physiology. Renal physiology 20101001
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Short-term effects of crossover treatment with silodosin and tamsulosin hydrochloride for lower urinary tract symptoms associated with benign prostatic hyperplasia.
International journal of urology : official journal of the Japanese Urological Association 20101001
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Editorial comment to short-term effects of crossover treatment with silodosin and tamsulosin hydrochloride for lower urinary tract symptoms associated with benign prostatic hyperplasia.
International journal of urology : official journal of the Japanese Urological Association 20101001
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(RS)-1-(1-Acetyl-indolin-5-yl)-2-chloro-propan-1-one.
Acta crystallographica. Section E, Structure reports online 20100701
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Effects of the selective alpha 1a-adrenoceptor antagonist silodosin on ECGs of healthy men in a randomized, double-blind, placebo- and moxifloxacin-controlled study.
Clinical pharmacology and therapeutics 20100501
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Urodynamic effects of silodosin, a new alpha 1A-adrenoceptor selective antagonist, for the treatment of benign prostatic hyperplasia.
Neurourology and urodynamics 20100401
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Torsades de Pointes induced by a combination of garenoxacin and disopyramide and other cytochrome P450, family 3, subfamily A polypeptide-4-influencing drugs during hypokalemia due to licorice.
Clinical and experimental nephrology 20100401
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Lack of pharmacodynamic interaction of silodosin, a highly selective alpha1a-adrenoceptor antagonist, with the phosphodiesterase-5 inhibitors sildenafil and tadalafil in healthy men.
Urology 20100301
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Impact of dry ejaculation caused by highly selective alpha1A-blocker: randomized, double-blind, placebo-controlled crossover pilot study in healthy volunteer men.
The journal of sexual medicine 20100301
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Visualization and tissue distribution of alpha1L-adrenoceptor in human prostate by the fluorescently labeled ligand Alexa-488-silodosin.
The Journal of urology 20100201
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Silodosin for benign prostatic hyperplasia.
The Annals of pharmacotherapy 20100201
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New Drugs2010, PART 1.
Nursing 20100201
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Effects of silodosin and naftopidil on the distal ureter and cardiovascular system in anesthetized dogs: comparison of potential medications for distal ureteral stone passage.
The Journal of urology 20100101
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[Investigation of adverse events and the continuance rate of silodosin in all patients who received silodosin for lower urinary tract symptoms suggestive of benign prostatic hyperplasia].
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20100101
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Gateways to clinical trials.
Methods and findings in experimental and clinical pharmacology 20100101
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The add-on effect of solifenacin for patients with remaining overactive bladder after treatment with tamsulosin for lower urinary tract symptoms suggestive of benign prostatic obstruction.
Advances in urology 20100101
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Silodosin in the treatment of benign prostatic hyperplasia.
Drug design, development and therapy 20100101
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Gene expressions and mechanical functions of α1-adrenoceptor subtypes in mouse ureter.
World journal of urology 20091201
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Silodosin in the treatment of the signs and symptoms of benign prostatic hyperplasia: a 9-month, open-label extension study.
Urology 20091201
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Efficacy of silodosin for relieving benign prostatic obstruction: prospective pressure flow study.
The Journal of urology 20091201
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Determination of silodosin in human plasma by liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091101
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Silodosin: a selective alpha1A-adrenergic receptor antagonist for the treatment of benign prostatic hyperplasia.
Clinical therapeutics 20091101
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Expression of distinct alpha 1-adrenoceptor phenotypes in the iris of pigmented and albino rabbits.
British journal of pharmacology 20090901
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Orgasm is preserved regardless of ejaculatory dysfunction with selective alpha1A-blocker administration.
International journal of impotence research 20090901
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Mechanical function and gene expression of alpha(1)-adrenoceptor subtypes in dog intravesical ureter.
Urology 20090801
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Effects of four different alpha(1)-adrenoceptor antagonists on alpha-adrenoceptor agonist-induced contractions in isolated mouse and hamster ureters.
Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20090801
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Effects of silodosin and tamsulosin on the urethra and cardiovascular system in young and old dogs with benign prostatic hyperplasia.
European journal of pharmacology 20090624
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Short- and long-term effects of silodosin, a selective alpha 1A-adrenoceptor antagonist, on ejaculatory function in rats.
BJU international 20090601
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Rapid efficacy of the highly selective alpha1A-adrenoceptor antagonist silodosin in men with signs and symptoms of benign prostatic hyperplasia: pooled results of 2 phase 3 studies.
The Journal of urology 20090601
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Silodosin (Rapaflo) for benign prostatic hyperplasia.
The Medical letter on drugs and therapeutics 20090112
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Role of alpha1-adrenergic receptors in detrusor overactivity induced by cold stress in conscious rats.
Neurourology and urodynamics 20090101
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New drugs: milnacipran hydrochloride, fesoterodine fumarate, and silodosin.
Journal of the American Pharmacists Association : JAPhA 20090101
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Efficacy of alpha-Adrenergic Receptor Blockers in the Treatment of Male Lower Urinary Tract Symptoms.
Reviews in urology 20090101
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Identification of alpha 1L-adrenoceptor in mice and its abolition by alpha 1A-adrenoceptor gene knockout.
British journal of pharmacology 20081201
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[Multi-center trial on the early effects of silodosin on lower urinary tract symptoms associated with benign prostatic hyperplasia].
Hinyokika kiyo. Acta urologica Japonica 20081201
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Computational studies of the binding site of alpha1A-adrenoceptor antagonists.
Journal of molecular modeling 20081001
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Ejaculatory dysfunction caused by the new alpha1-blocker silodosin: A preliminary study to analyze human ejaculation using color Doppler ultrasonography.
International journal of urology : official journal of the Japanese Urological Association 20081001
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Early efficacy of silodosin in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia.
International journal of urology : official journal of the Japanese Urological Association 20081001
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The involvement of urothelial alpha1A adrenergic receptor in controlling the micturition reflex.
Biomedical research (Tokyo, Japan) 20081001
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Inhibition of Seminal emission is the main cause of anejaculation induced by a new highly selective alpha1A-blocker in normal volunteers.
The journal of sexual medicine 20080901
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Gateways to clinical trials.
Methods and findings in experimental and clinical pharmacology 20080601
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Different affinities of native alpha1B-adrenoceptors for ketanserin between intact tissue segments and membrane preparations.
European journal of pharmacology 20080428
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Identification of the alpha1L-adrenoceptor in rat cerebral cortex and possible relationship between alpha1L- and alpha1A-adrenoceptors.
British journal of pharmacology 20080401
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Mutational analysis of the alpha 1a-adrenergic receptor binding pocket of antagonists by radioligand binding assay.
Biological & pharmaceutical bulletin 20080401
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In vivo study on the effects of alpha1-adrenoceptor antagonists on intraurethral pressure in the prostatic urethra and intraluminal pressure in the vas deferens in male dogs.
European journal of pharmacology 20080202
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Silodosin, a novel selective alpha 1A-adrenoceptor selective antagonist for the treatment of benign prostatic hyperplasia.
Expert opinion on investigational drugs 20071201
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Expressions and mechanical functions of alpha1-adrenoceptor subtypes in hamster ureter.
European journal of pharmacology 20071114
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Alpha1-adrenoceptors and ejaculatory function.
British journal of pharmacology 20071001
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Prediction of alpha1-adrenoceptor occupancy in the human prostate from plasma concentrations of silodosin, tamsulosin and terazosin to treat urinary obstruction in benign prostatic hyperplasia.
Biological & pharmaceutical bulletin 20070701
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Identification of alpha-1L and alpha-1A adrenoceptors in human prostate by tissue segment binding.
The Journal of urology 20070101
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Search for new alpha1a-adrenoceptor-selective antagonist for treating lower urinary tract symptoms associated with benign prostatic hyperplasia.
Indian journal of urology : IJU : journal of the Urological Society of India 20070101
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Silodosin, a new alpha1A-adrenoceptor-selective antagonist for treating benign prostatic hyperplasia: results of a phase III randomized, placebo-controlled, double-blind study in Japanese men.
BJU international 20061101
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[Pharmacological and clinical profile of silodosin (URIEF Cap. 2 mg, 4 mg)].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20061001
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A selective alpha1A-adrenoceptor antagonist inhibits detrusor overactivity in a rat model of benign prostatic hyperplasia.
The Journal of urology 20060901
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[Alpha1-adrenoceptor subtypes and alpha1-adrenoceptor antagonists].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20060301
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[Alpha1-adrenoceptor subtype selectivity and organ specificity of silodosin (KMD-3213)].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20060301
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[Effects of silodosin (KMD-3213) on phenylephrine-induced increase in intraurethral pressure and blood pressure in rats--study of the selectivity for lower urinary tract].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20060301
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[Effect of silodosin on intraurethral pressure increase induced by hypogastric nerve stimulation in dogs with benign prostatic hyperplasia].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20060301
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[Duration of action of silodosin (KMD-3213) against phenylephrine-induced increase in intraurethral pressure in rats].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20060301
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[Pharmacokinetics and disposition of silodosin (KMD-3213)].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20060301
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[Toxicity profile of silodosin (KMD-3213)].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20060301
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[Pharmacokinetic profile of silodosin in clinical practice].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20060301
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Uroselectivity in male dogs of silodosin (KMD-3213), a novel drug for the obstructive component of benign prostatic hyperplasia.
Neurourology and urodynamics 20060101
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Cardiovascular effects of the selective alphalA-adrenoceptor antagonist silodosin (KMD-3213), a drug for the treatment of voiding dysfunction.
Arzneimittel-Forschung 20060101
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Correlation between vasoconstrictor roles and mRNA expression of alpha1-adrenoceptor subtypes in blood vessels of genetically engineered mice.
British journal of pharmacology 20051001
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Identification of alpha-1L adrenoceptor in rabbit ear artery.
The Journal of pharmacology and experimental therapeutics 20040901
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Carvedilol selectively inhibits oscillatory intracellular calcium changes evoked by human alpha1D- and alpha1B-adrenergic receptors.
Cardiovascular research 20040901
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Alpha-1D adrenoceptors are involved in reserpine-induced supersensitivity of rat tail artery.
British journal of pharmacology 20040601
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KMD 3213: KAD 3213, silodosin.
Drugs in R&D 20040101
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Systemic alpha 1A-adrenoceptor antagonist inhibits neointimal growth after balloon injury of rat carotid artery.
American journal of physiology. Heart and circulatory physiology 20030101
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Identification of binding sites of prazosin, tamsulosin and KMD-3213 with alpha(1)-adrenergic receptor subtypes by molecular modeling.
Life sciences 20021011
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Alpha(1)-adrenoceptor stimulation directly induces growth of vascular wall in vivo.
American journal of physiology. Heart and circulatory physiology 20021001
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Effects of KMD-3213, a uroselective alpha 1A-adrenoceptor antagonist, on the tilt-induced blood pressure response in normotensive rats.
Japanese journal of pharmacology 20021001
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Alpha-1 adrenoceptor up-regulation induced by prazosin but not KMD-3213 or reserpine in rats.
British journal of pharmacology 20020401
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Differences in the subcellular localization of alpha1-adrenoceptor subtypes can affect the subtype selectivity of drugs in a study with the fluorescent ligand BODIPY FL-prazosin.
Life sciences 20020322
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Effect of KMD-3213, an alpha1A-adrenoceptor antagonist, on the prostatic urethral pressure and blood pressure in male decerebrate dogs.
International journal of urology : official journal of the Japanese Urological Association 20010401
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In vivo demonstration of alpha(1A)-adrenoceptor subtype selectivity of KMD-3213 in rat tissues.
The Journal of pharmacology and experimental therapeutics 20010101
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KMD-3213, a novel, potent, alpha 1a-adrenoceptor-selective antagonist: characterization using recombinant human alpha 1-adrenoceptors and native tissues.
Molecular pharmacology 19950801
