1613724-42-7 | Hth-01-015

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$14.00	$10.00
50mg	98% by HPLC	in stock	$538.00	$377.00
100mg	98% by HPLC	in stock	$890.00	$623.00
500mg	98% by HPLC	in stock	$2,745.00	$1,921.00
1000mg	98% by HPLC	in stock	$4,358.00	$3,051.00

Description

• Catalog Number: AA83255
• Chemical Name: Hth-01-015
• CAS Number: 1613724-42-7
• Molecular Formula: C26H28N8O
• Molecular Weight: 468.5535
• MDL Number: MFCD28167816
• SMILES: Cc1nc(Nc2cnn(c2)C2CCNCC2)nc2c1n(C)c(=O)c1c(n2C)cc2c(c1)cccc2

Computed Properties

• Complexity: 762
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 35
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 3
• XLogP3: 3.2

Literature

• Interplay between Polo kinase, LKB1-activated NUAK1 kinase, PP1βMYPT1 phosphatase complex and the SCFβTrCP E3 ubiquitin ligase.

  The Biochemical journal 20140715

• Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases.

  The Biochemical journal 20140101