16153-81-4 | 4-(4-Methylpiperazino)aniline

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$8.00	$5.00
5g	98%	in stock	$9.00	$7.00
10g	98%	in stock	$11.00	$8.00
25g	98%	in stock	$24.00	$17.00
100g	98%	in stock	$85.00	$59.00
500g	98%	in stock	$368.00	$257.00

Description

• Catalog Number: AA87497
• Chemical Name: 4-(4-Methylpiperazino)aniline
• CAS Number: 16153-81-4
• Molecular Formula: C11H17N3
• Molecular Weight: 191.2728
• MDL Number: MFCD00021818
• SMILES: CN1CCN(CC1)c1ccc(cc1)N

Computed Properties

• Complexity: 167
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 1.2

Upstream Synthesis Route

4-(4-Methylpiperazin-1-yl)phenylamine, also known as $name$, is a versatile compound widely used in chemical synthesis for its unique and valuable properties. In organic chemistry, this compound serves as a crucial building block for the synthesis of various biologically active molecules and pharmaceutical intermediates. Its primary application lies in the formation of complex organic structures through a series of synthetic reactions. By incorporating 4-(4-Methylpiperazin-1-yl)phenylamine into reaction pathways, chemists can effectively introduce specific functional groups and structural motifs, ultimately leading to the creation of novel compounds with diverse applications in the field of medicinal chemistry and drug development. Furthermore, its compatibility with a range of synthetic methodologies and its ability to undergo various transformations make it a valuable tool in the hands of synthetic chemists seeking to explore new chemical space and develop innovative molecules with potential therapeutic benefits.

Literature

• Antistaphylococcal activity of DNA-interactive pyrrolobenzodiazepine (PBD) dimers and PBD-biaryl conjugates.

  The Journal of antimicrobial chemotherapy 20120701

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Structure-affinity relationships of a unique nicotinic ligand: N(1)-dimethyl-N(4)-phenylpiperazinium iodide (DMPP).

  Journal of medicinal chemistry 20011108