161796-78-7 | sodium 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methane]sulfinyl}-1H-1,3-benzodiazol-1-ide

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$11.00	$8.00
1g	98%	in stock	$13.00	$9.00
5g	98%	in stock	$24.00	$17.00
10g	98%	in stock	$47.00	$33.00
25g	98%	in stock	$72.00	$51.00
100g	98%	in stock	$216.00	$152.00

Description

• Catalog Number: AA87783
• Chemical Name: sodium 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methane]sulfinyl}-1H-1,3-benzodiazol-1-ide
• CAS Number: 161796-78-7
• Molecular Formula: C17H18N3NaO3S
• Molecular Weight: 367.39788999999996
• MDL Number: MFCD07802816
• SMILES: COc1ccc2c(c1)[n-]c(n2)[S@@](=O)Cc1ncc(c(c1C)OC)C.[Na+]

Computed Properties

• Complexity: 459
• Covalently-Bonded Unit Count: 2
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 25
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 5

Literature

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  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20121201

• COX-2 mRNA is increased in oesophageal mucosal cells by a proton pump inhibitor.

  ANZ journal of surgery 20121001

• A combination of esomeprazole and aspirin reduces tissue concentrations of prostaglandin E(2) in patients with Barrett's esophagus.

  Gastroenterology 20121001

• Partial symptom-response to proton pump inhibitors in patients with non-erosive reflux disease or reflux oesophagitis - a post hoc analysis of 5796 patients.

  Alimentary pharmacology & therapeutics 20121001

• Evaluation of six proton pump inhibitors as inhibitors of various human cytochromes P450: focus on cytochrome P450 2C19.

  Drug metabolism and disposition: the biological fate of chemicals 20120901

• Concomitant symptoms itemized in the Reflux Disease Questionnaire are associated with attenuated heartburn response to acid suppression.

  The American journal of gastroenterology 20120901

• Meta-analysis: esomeprazole or rabeprazole vs. first-generation pump inhibitors in the treatment of Helicobacter pylori infection.

  Alimentary pharmacology & therapeutics 20120901

• Pharmacokinetic and clinical evaluation of esomeprazole and ASA for the prevention of gastroduodenal ulcers in cardiovascular patients.

  Expert opinion on drug metabolism & toxicology 20120901

• Evaluation of the pharmacodynamics of acetylsalicylic acid 81 mg with or without esomeprazole 20 mg in healthy volunteers.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20120801

• Phase I, multicenter, randomized, open-label study evaluating the pharmacokinetics and safety profile of repeated once-daily doses of intravenous esomeprazole in children 0 to 17 years of age.

  Clinical therapeutics 20120801

• Esomeprazole for the treatment of GERD in infants ages 1-11 months.

  Journal of pediatric gastroenterology and nutrition 20120701

• Efficacy of 5-day levofloxacin-containing concomitant therapy in eradication of Helicobacter pylori infection.

  Gastroenterology 20120701

• Esomeprazole alone compared with esomeprazole plus aspirin for the treatment of aspirin-related peptic ulcers.

  The American journal of gastroenterology 20120701

• Randomised clinical trial: esomeprazole for the prevention of nonsteroidal anti-inflammatory drug-related peptic ulcers in Japanese patients.

  Alimentary pharmacology & therapeutics 20120701

• High-dose, ten-day esomeprazole, amoxicillin and metronidazole triple therapy achieves high Helicobacter pylori eradication rates.

  Alimentary pharmacology & therapeutics 20120701

• Work productivity improvement after acid suppression in patients with uninvestigated dyspepsia.

  Danish medical journal 20120701

• Regurgitation is less responsive to acid suppression than heartburn in patients with gastroesophageal reflux disease.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20120601

• Randomized comparison of two non-bismuth-containing second-line rescue therapies for Helicobacter pylori.

  Helicobacter 20120601

• Pharmacokinetics and relative bioavailability of a fixed-dose combination of enteric-coated naproxen and non-enteric-coated esomeprazole magnesium.

  Journal of clinical pharmacology 20120501

• High-dose esomeprazole is required for intraesophageal acid control in gastroesophageal reflux disease patients with hiatus hernia.

  Journal of gastroenterology and hepatology 20120501

• Esomeprazole formulary exclusion: impact on total health care services use and costs.

  Postgraduate medicine 20120501

• A randomized, 2-period, crossover design study to assess the effects of dexlansoprazole, lansoprazole, esomeprazole, and omeprazole on the steady-state pharmacokinetics and pharmacodynamics of clopidogrel in healthy volunteers.

  Journal of the American College of Cardiology 20120403

• A comparison of the acid-inhibitory effects of esomeprazole and rabeprazole in relation to pharmacokinetics and CYP2C19 polymorphism.

  Alimentary pharmacology & therapeutics 20120401

• Doxycycline-based quadruple regimen versus routine quadruple regimen for rescue eradication of Helicobacter pylori: an open-label control study in Chinese patients.

  Singapore medical journal 20120401

• Esomeprazole compared with famotidine in the prevention of upper gastrointestinal bleeding in patients with acute coronary syndrome or myocardial infarction.

  The American journal of gastroenterology 20120301

• Esomeprazole relieves upper gastrointestinal symptoms in high-risk and average-risk NSAID users in daily clinical practice: results from an open-label study.

  European journal of gastroenterology & hepatology 20120301

• Comparison of levofloxacin-containing sequential and standard triple therapies for the eradication of Helicobacter pylori.

  European journal of internal medicine 20120301

• Acetylsalicylic acid/esomeprazole fixed-dose combination.

  Drugs & aging 20120301

• Effects of proton pump inhibitors on platelet function in patients receiving clopidogrel: a systematic review.

  Drug safety 20120201

• Evaluation of a four-drug, three-antibiotic, nonbismuth-containing 'concomitant' therapy as first-line Helicobacter pylori eradication regimen in Greece.

  Helicobacter 20120201

• Comparison of bismuth-containing quadruple and concomitant therapies as a first-line treatment option for Helicobacter pylori.

  The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 20120201

• A validated stability indicating ultra performance liquid chromatographic method for determination of impurities in Esomeprazole magnesium gastro resistant tablets.

  Journal of pharmaceutical and biomedical analysis 20120105

• Evolution of gastro-oesophageal reflux disease over 5 years under routine medical care--the ProGERD study.

  Alimentary pharmacology & therapeutics 20120101

• Results of ambulatory pH monitoring do not reliably predict response to therapy in patients with eosinophilic oesophagitis.

  Alimentary pharmacology & therapeutics 20120101

• Agranulocytosis induced by proton pump inhibitors.

  Journal of clinical gastroenterology 20120101

• The influence of esomeprazole and cisapride on gastroesophageal reflux during anesthesia in dogs.

  Journal of veterinary internal medicine 20120101

• Omeprazole- and esomeprazole-associated hypomagnesaemia: data mining of the public version of the FDA Adverse Event Reporting System.

  International journal of medical sciences 20120101

• A fixed-dose combination of naproxen and esomeprazole magnesium has comparable upper gastrointestinal tolerability to celecoxib in patients with osteoarthritis of the knee: results from two randomized, parallel-group, placebo-controlled trials.

  Annals of medicine 20111201

• Randomized trial on 14 versus 7 days of esomeprazole, moxifloxacin, and amoxicillin for second-line or rescue treatment of Helicobacter pylori infection.

  Helicobacter 20111201

• Impact of a fixed-dose combination of naproxen and esomeprazole magnesium on serum thromboxane B2 inhibition by low-dose aspirin over 5 days in healthy adults: a phase I, randomized, double-blind, placebo-controlled, noninferiority trial.

  Clinical therapeutics 20111201

• Ventricular bigeminy associated with voriconazole, methadone and esomeprazole.

  International journal of clinical pharmacy 20111201

• Severe exfoliative dermatitis caused by esomeprazole.

  Journal of the American Geriatrics Society 20111201

• The effect of antireflux treatment on patients with gastroesophageal reflux disease undergoing a mental arithmetic stressor.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20111101

• Doubling the dose of clopidogrel restores the loss of antiplatelet effect induced by esomeprazole.

  Thrombosis research 20111101

• The proton pump inhibitor, omeprazole, but not lansoprazole or pantoprazole, is a metabolism-dependent inhibitor of CYP2C19: implications for coadministration with clopidogrel.

  Drug metabolism and disposition: the biological fate of chemicals 20111101

• Effect of pH and comedication on gastrointestinal absorption of posaconazole: monitoring of intraluminal and plasma drug concentrations.

  Clinical pharmacokinetics 20111101

• Effect of esomeprazole versus famotidine on platelet inhibition by clopidogrel: a double-blind, randomized trial.

  American heart journal 20111101

• [Esomeprazole-induced subacute cutaneous lupus erythematosus].

  Actas dermo-sifiliograficas 20111001

• Chronic cough and esomeprazole: a double-blind placebo-controlled parallel study.

  Respirology (Carlton, Vic.) 20111001

• Relationship between cardiovascular outcomes and proton pump inhibitor use in patients receiving dual antiplatelet therapy after acute coronary syndrome.

  Pharmacoepidemiology and drug safety 20111001

• Randomised clinical trial: the burden of illness of uninvestigated dyspepsia before and after treatment with esomeprazole--results from the STARS II study.

  Alimentary pharmacology & therapeutics 20111001

• Whole-cell oxidation of omeprazole sulfide to enantiopure esomeprazole with Lysinibacillus sp. B71.

  Bioresource technology 20110901

• Randomized comparison of two nonbismuth-containing rescue therapies for Helicobacter pylori.

  The American journal of the medical sciences 20110901

• Supplementation of Los Angeles classification with esophageal mucosa index of hemoglobin can predict the treatment response of erosive reflux esophagitis.

  Surgical endoscopy 20110801

• Influence of esomeprazole on hypoglycemic activity of oral antidiabetic agents in rats and rabbits.

  Molecular and cellular biochemistry 20110801

• Empirical modified sequential therapy containing levofloxacin and high-dose esomeprazole in second-line therapy for Helicobacter pylori infection: a multicentre clinical trial.

  The Journal of antimicrobial chemotherapy 20110801

• Race affects healing of erosive oesophagitis in patients treated with proton pump inhibitors.

  Alimentary pharmacology & therapeutics 20110801

• Randomized double-blind placebo-controlled crossover study to determine the effects of esomeprazole on inhibition of platelet function by clopidogrel.

  Journal of thrombosis and haemostasis : JTH 20110801

• Reducing the risk of gastroduodenal ulcers with a fixed combination of esomeprazole and low-dose acetyl salicylic acid.

  Expert review of gastroenterology & hepatology 20110801

• Treatment of non-erosive reflux disease with a proton pump inhibitor in Chinese patients: a randomized controlled trial.

  Journal of gastroenterology 20110701

• Measurement of mucosal conductivity by MII is a potential marker of mucosal integrity restored in infants on acid-suppression therapy.

  Journal of pediatric gastroenterology and nutrition 20110701

• Hypomagnesaemia/hypokalemia associated with the use of esomeprazole.

  Current drug safety 20110701

• Impact of acid suppression on upper gastrointestinal pH and motility.

  Digestive diseases and sciences 20110601

• Fixed-dose combination of enteric-coated naproxen and immediate-release esomeprazole has comparable efficacy to celecoxib for knee osteoarthritis: two randomized trials.

  Current medical research and opinion 20110601

• Intravenous esomeprazole: a pharmacoeconomic profile of its use in the prevention of recurrent peptic ulcer bleeding.

  PharmacoEconomics 20110601

• Effects of different proton pump inhibitors on cardiac contractility in isolated human failing myocardium.

  The Journal of cardiovascular surgery 20110601

• Prospective, randomized, placebo-controlled evaluation of esomeprazole in coronary artery disease patients. EPAC: esomeprazole prevention of atypical chest pains.

  The Journal of invasive cardiology 20110601

• Laparoscopic antireflux surgery vs esomeprazole treatment for chronic GERD: the LOTUS randomized clinical trial.

  JAMA 20110518

• Prevention of peptic ulcers with esomeprazole in patients at risk of ulcer development treated with low-dose acetylsalicylic acid: a randomised, controlled trial (OBERON).

  Heart (British Cardiac Society) 20110515

• Randomised clinical trial: twice daily esomeprazole 40 mg vs. pantoprazole 40 mg in Barrett's oesophagus for 1 year.

  Alimentary pharmacology & therapeutics 20110501

• Rabeprazole extended-release 50 mg compared with esomeprazole 40 mg and rabeprazole delayed release 20 mg.

  Alimentary pharmacology & therapeutics 20110501

• Helicobacter pylori infection: a randomized, controlled study comparing 2 rescue therapies after failure of standard triple therapies.

  Medicine 20110501

• [Evaluation of efficacy of esomeprazole treatment in patients with laryngopharyngeal reflux].

  Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 20110501

• Risk factors associated with Helicobacter pylori infection treatment failure in a high prevalence area.

  Epidemiology and infection 20110401

• Effects of long-term PPI treatment on producing bowel symptoms and SIBO.

  European journal of clinical investigation 20110401

• Evaluation of Helicobacter pylori eradication by triple therapy plus Lactobacillus acidophilus compared to triple therapy alone.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20110401

• An open-label, parallel, multiple-dose study comparing the pharmacokinetics and gastric acid suppression of rabeprazole extended-release with esomeprazole 40 mg and rabeprazole delayed-release 20 mg in healthy volunteers.

  Alimentary pharmacology & therapeutics 20110401

• Long-term safety of naproxen and esomeprazole magnesium fixed-dose combination: phase III study in patients at risk for NSAID-associated gastric ulcers.

  Current medical research and opinion 20110401

• Comparison of infusion or low-dose proton pump inhibitor treatments in upper gastrointestinal system bleeding.

  European journal of internal medicine 20110401

• New effective treatment regimen for children infected with a double-resistant Helicobacter pylori strain.

  Journal of pediatric gastroenterology and nutrition 20110401

• Five-year examination of utilization and drug cost outcomes associated with benefit design changes including reference pricing for proton pump inhibitors in a state employee health plan.

  Journal of managed care pharmacy : JMCP 20110401

• Esomeprazole but not pantoprazole is associated with lower plasma concentrations of clopidogrel's active metabolite.

  The Annals of pharmacotherapy 20110401

• The application of atomic absorption spectrometry for the determination of residual active pharmaceutical ingredients in cleaning validation samples.

  Drug development and industrial pharmacy 20110301

• Esomeprazole with clopidogrel reduces peptic ulcer recurrence, compared with clopidogrel alone, in patients with atherosclerosis.

  Gastroenterology 20110301

• Naproxen/esomeprazole fixed-dose combination: for the treatment of arthritic symptoms and to reduce the risk of gastric ulcers.

  Drugs & aging 20110301

• Concomitant irritable bowel syndrome is associated with failure of step-down on-demand proton pump inhibitor treatment in patients with gastro-esophageal reflux disease.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20110201

• Intragastric acidity during administration of generic omeprazole or esomeprazole - a randomised, two-way crossover study including CYP2C19 genotyping.

  Alimentary pharmacology & therapeutics 20110201

• Safety and tolerability of high-dose intravenous esomeprazole for prevention of peptic ulcer rebleeding.

  Advances in therapy 20110201

• Evaluation of bioequivalence between a single-capsule formulation of esomeprazole 40 mg and acetylsalicylic acid 325 mg and the monotherapies given separately in healthy volunteers.

  International journal of clinical pharmacology and therapeutics 20110201

• Effects of esomeprazole on healing of nonsteroidal anti-inflammatory drug (NSAID)-induced gastric ulcers in the presence of a continued NSAID treatment: Characterization of molecular mechanisms.

  Pharmacological research 20110101

• Randomised clinical trial: identification of responders to short-term treatment with esomeprazole for dyspepsia in primary care - a randomised, placebo-controlled study.

  Alimentary pharmacology & therapeutics 20110101

• Randomised clinical trial: high-dose acid suppression for chronic cough - a double-blind, placebo-controlled study.

  Alimentary pharmacology & therapeutics 20110101

• Randomised clinical trial: a novel rabeprazole extended release 50 mg formulation vs. esomeprazole 40 mg in healing of moderate-to-severe erosive oesophagitis - the results of two double-blind studies.

  Alimentary pharmacology & therapeutics 20110101

• Effects of multistrain probiotic-containing yogurt on second-line triple therapy for Helicobacter pylori infection.

  Journal of gastroenterology and hepatology 20110101

• Effects of structured follow-up and of more effective acid inhibitory treatment in the management of GORD patients in a Swedish primary-care setting: a randomized, open-label study.

  Clinical drug investigation 20110101

• Effects of intravenously administered esomeprazole sodium on gastric juice pH in adult female horses.

  Journal of veterinary internal medicine 20110101

• [Interaction between clopidogrel and proton pump inhibitors].

  Nederlands tijdschrift voor geneeskunde 20110101

• Effect of proton pump inhibitors on platelet inhibition activity of clopidogrel in Chinese patients with percutaneous coronary intervention.

  Vascular health and risk management 20110101

• Bioequivalence study of two esomeprazole enteric coated formulations in healthy Chinese volunteers.

  Arzneimittel-Forschung 20110101

• Acid control cannot be improved with a modified-release formulation of a proton pump inhibitor compared with twice-daily dosing of the conventional formulation.

  Digestive diseases and sciences 20101201

• Treatment with a proton pump inhibitor improves glycaemic control in type 2 diabetic patients - a retrospective analysis.

  Diabetes research and clinical practice 20101201

• Cost reduction associated with restriction policy on dispensing intravenous esomeprazole in Lebanon.

  Pharmacy world & science : PWS 20101201

• Esomeprazole for the treatment of peptic ulcer bleeding.

  Expert review of gastroenterology & hepatology 20101201

• Healing of erosive esophagitis and improvement of symptoms of gastroesophageal reflux disease after esomeprazole treatment in children 12 to 36 months old.

  Journal of pediatric gastroenterology and nutrition 20101101

• The gain in quality-adjusted life months by switching to esomeprazole in those with continued reflux symptoms in primary care: EncomPASS--a cluster-randomized trial.

  The American journal of gastroenterology 20101101

• Treatment of clinically diagnosed laryngopharyngeal reflux disease.

  Archives of otolaryngology--head & neck surgery 20101101

• Esomeprazole-induced hyperchromograninemia in the absence of concomitant hypergastrinemia.

  Nature reviews. Gastroenterology & hepatology 20101101

• The effects of dose and timing of esomeprazole administration on 24-h, daytime and night-time acid inhibition in healthy volunteers.

  Alimentary pharmacology & therapeutics 20101101

• Efficacy and tolerability of first-line triple therapy with levofloxacin and amoxicillin plus esomeprazole or rabeprazole for the eradication of Helicobacter pylori infection and the effect of CYP2C19 genotype: a 1-week, randomized, open-label study in Chinese adults.

  Clinical therapeutics 20101101

• Evaluation of the pharmacokinetic interaction between lesogaberan (AZD3355) and esomeprazole in healthy subjects.

  Drugs in R&D 20101101

• Racemization of the gastrointestinal antisecretory chiral drug esomeprazole magnesium via the pyramidal inversion mechanism: A theoretical study.

  Chirality 20101001

• Comparison of the once-daily levofloxacin-containing triple therapy with the twice-daily standard triple therapy for first-line Helicobacter pylori eradication: a prospective randomised study.

  International journal of clinical practice 20101001

• The effects of high-dose esomeprazole on gastric and oesophageal acid exposure and molecular markers in Barrett's oesophagus.

  Alimentary pharmacology & therapeutics 20101001

• Proton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cells.

  Cell death & disease 20101001

• Naproxen/esomeprazole (Vimovo).

  The Medical letter on drugs and therapeutics 20100920

• Direct HPLC enantioseparation of omeprazole and its chiral impurities: application to the determination of enantiomeric purity of esomeprazole magnesium trihydrate.

  Journal of pharmaceutical and biomedical analysis 20100905

• Nonpigmented fixed drug eruption induced by esomeprazole.

  Cutaneous and ocular toxicology 20100901

• Twelve-month endoscopic and histological analysis following proton-pump inhibitor-based triple therapy in Helicobacter pylori-positive patients with gastric ulcers.

  Scandinavian journal of gastroenterology 20100901

• [Effect of birid triple viable on peptic ulcer patients with Helicobacter pylori infection].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20100901

• Relationship between symptom response and esophageal pH level on standard dose of esomeprazole treatment for gastroesophageal reflux disease.

  Chinese medical journal 20100805

• Dual proton pump inhibitor plus amoxicillin as an empiric anti-H. pylori therapy: studies from the United States.

  Journal of gastroenterology 20100801

• E3710, a new proton pump inhibitor, with a long-lasting inhibitory effect on gastric acid secretion.

  The Journal of pharmacology and experimental therapeutics 20100801

• Clinical trial: evaluation of gastric acid suppression with three doses of immediate-release esomeprazole in the fixed-dose combination of PN 400 (naproxen/esomeprazole magnesium) compared with naproxen 500 mg and enteric-coated esomeprazole 20 mg: a randomized, open-label, Phase I study in healthy volunteers.

  Alimentary pharmacology & therapeutics 20100801

• Clinical trial: the incidence of NSAID-associated endoscopic gastric ulcers in patients treated with PN 400 (naproxen plus esomeprazole magnesium) vs. enteric-coated naproxen alone.

  Alimentary pharmacology & therapeutics 20100801

• A model of healing of Los Angeles grades C and D reflux oesophagitis: is there an optimal time of acid suppression for maximal healing?

  Alimentary pharmacology & therapeutics 20100801

• Effect of the proton pump inhibitor esomeprazole on the oral absorption and pharmacokinetics of nilotinib.

  Journal of clinical pharmacology 20100801

• Rabeprazole can overcome the impact of CYP2C19 polymorphism on quadruple therapy.

  Helicobacter 20100801

• pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity.

  International journal of cancer 20100701

• Esomeprazole-induced rhabdomyolysis in a patient with heart failure.

  Intensive care medicine 20100701

• Pantoprazole does not influence the antiplatelet effect of clopidogrel-a whole blood aggregometry study after coronary stenting.

  Journal of cardiovascular pharmacology 20100701

• Clinical trial: gastric acid suppression in Hispanic adults with symptomatic gastro-oesophageal reflux disease - comparator study of esomeprazole, lansoprazole and pantoprazole.

  Alimentary pharmacology & therapeutics 20100701

• Clinical trial: esomeprazole for moderate-to-severe nighttime heartburn and gastro-oesophageal reflux disease-related sleep disturbances.

  Alimentary pharmacology & therapeutics 20100701

• Relative bioavailability and pharmacokinetic properties of two different enteric formulations of esomeprazole in healthy Bangladeshi male volunteers: An open-label, single-dose, randomized-sequence, two-way crossover study.

  Clinical therapeutics 20100701

• Accuracy of the diagnosis of GORD by questionnaire, physicians and a trial of proton pump inhibitor treatment: the Diamond Study.

  Gut 20100601

• Second-line and rescue therapies for Helicobacter pylori eradication in clinical practice.

  Journal of gastrointestinal and liver diseases : JGLD 20100601

• Pharmacogenetics of esomeprazole or rabeprazole-based triple therapy in Helicobacter pylori eradication in Hong Kong non-ulcer dyspepsia Chinese subjects.

  Journal of clinical pharmacy and therapeutics 20100601

• Effect of esomeprazole 40 mg once or twice daily on asthma: a randomized, placebo-controlled study.

  American journal of respiratory and critical care medicine 20100515

• Comparison of esomeprazole to aerosolized, swallowed fluticasone for eosinophilic esophagitis.

  Digestive diseases and sciences 20100501

• Long-term outcome of microscopic esophagitis in chronic GERD patients treated with esomeprazole or laparoscopic antireflux surgery in the LOTUS trial.

  The American journal of gastroenterology 20100501

• Impact of oesophagitis classification in evaluating healing of erosive oesophagitis after therapy with proton pump inhibitors: a pooled analysis.

  European journal of gastroenterology & hepatology 20100501

• Intravenous esomeprazole pharmacodynamics in critically ill patients.

  Current medical research and opinion 20100501

• [Prophylaxis use of posaconazole (P) in an hemato-oncology unit: a retrospective study].

  Pathologie-biologie 20100401

• Ten and eight-day sequential therapy in comparison to standard triple therapy for eradicating Helicobacter pylori infection: a randomized controlled study on efficacy and tolerability.

  Journal of clinical gastroenterology 20100401

• Possible acute thrombocytopenia post esomeprazole and hydantoin coadministration.

  Journal of pharmacy practice 20100401

• Factors influencing intercellular spaces in the rat esophageal epithelium.

  World journal of gastroenterology 20100307

• The pharmacodynamics and pharmacokinetics of S-tenatoprazole-Na 30 mg, 60 mg and 90 mg vs. esomeprazole 40 mg in healthy male subjects.

  Alimentary pharmacology & therapeutics 20100301

• Recurrence of acute myocardial infarction in patients discharged on clopidogrel and a proton pump inhibitor after stent placement for acute myocardial infarction.

  Clinical cardiology 20100301

• Counselling by primary care physicians may help patients with heartburn-predominant uninvestigated dyspepsia.

  Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20100301

• The effect of esomeprazole 20 mg twice daily on acoustic and perception parameters of the voice in laryngopharyngeal reflux.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20100201

• Efficacy of three different dosages of esomeprazole in the long-term management of reflux disease: a prospective, randomized study, using the wireless Bravo pH system.

  The American journal of gastroenterology 20100201

• Efficacy of four different moxifloxacin-based triple therapies for first-line H. pylori treatment.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20100201

• Delayed release film coating applications on oral solid dosage forms of proton pump inhibitors: case studies.

  Drug development and industrial pharmacy 20100201

• Bismuth-containing quadruple therapy as second-line treatment for Helicobacter pylori infection: effect of treatment duration and antibiotic resistance on the eradication rate in Korea.

  Helicobacter 20100201

• A comparison of the acid-inhibitory effects of esomeprazole and pantoprazole in relation to pharmacokinetics and CYP2C19 polymorphism.

  Alimentary pharmacology & therapeutics 20100101

• Oral buffered esomeprazole is superior to i.v. pantoprazole for rapid rise of intragastric pH: a wireless pH metry analysis.

  Journal of gastroenterology and hepatology 20100101

• Cost effectiveness of high-dose intravenous esomeprazole for peptic ulcer bleeding.

  PharmacoEconomics 20100101

• Esophageal hematoma mimicking downhill varices: resolution after esomeprazole therapy.

  Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates 20100101

• Esomeprazole for the treatment of erosive esophagitis in children: an international, multicenter, randomized, parallel-group, double-blind (for dose) study.

  BMC pediatrics 20100101

• Early marginal ulcer following Roux-en-Y gastric bypass under proton pump inhibitor treatment: prospective multicentric study.

  Arquivos de gastroenterologia 20100101

• Esomeprazole-induced photoallergic dermatitis.

  Journal of postgraduate medicine 20100101

• Effects of multiple-dose esomeprazole and pantoprazole on diazepam pharmacokinetic profile and pharmacodynamic effects on cognitive and psychomotor function in healthy volunteers.

  Arzneimittel-Forschung 20100101

• Differential effects of esomeprazole on the antiplatelet activity of clopidogrel in healthy individuals and patients after coronary stent implantation.

  The Journal of international medical research 20100101

• Clarithromycin-amoxycillin-containing triple therapy: a valid empirical first-line treatment for Helicobacter pylori eradication in Hong Kong?

  Helicobacter 20091201

• A single dose of intravenous esomeprazole decreases gastric secretion in healthy volunteers.

  Alimentary pharmacology & therapeutics 20091115

• [Effect of esomeprazole upon intestinal mucosal damage following traumatic brain injury in rats].

  Zhonghua yi xue za zhi 20091103

• Quantification of dental erosions in patients with GERD using optical coherence tomography before and after double-blind, randomized treatment with esomeprazole or placebo.

  The American journal of gastroenterology 20091101

• Effects of asymptomatic proximal and distal gastroesophageal reflux on asthma severity.

  American journal of respiratory and critical care medicine 20091101

• Moxifloxacin-containing triple therapy as second-line treatment for Helicobacter pylori infection: effect of treatment duration and antibiotic resistance on the eradication rate.

  Helicobacter 20091001

• Systematic review: standard- and double-dose proton pump inhibitors for the healing of severe erosive oesophagitis -- a mixed treatment comparison of randomized controlled trials.

  Alimentary pharmacology & therapeutics 20090915

• Furazolidone, co-amoxiclav, colloidal bismuth subcitrate, and esomeprazole for patients who failed to eradicate Helicobacter pylori with triple therapy.

  Digestive diseases and sciences 20090901

• Seven-day intravenous low-dose omeprazole infusion reduces peptic ulcer rebleeding for patients with comorbidities.

  Gastrointestinal endoscopy 20090901

• Predictors of heartburn resolution and erosive esophagitis in patients with GERD.

  Current medical research and opinion 20090901

• The pharmacology of esomeprazole and its role in gastric acid related diseases.

  Expert opinion on drug metabolism & toxicology 20090901

• Evaluation of the pharmacokinetic interaction between esomeprazole (40 mg) and acetylsalicylic acid (325 mg) in healthy volunteers.

  International journal of clinical pharmacology and therapeutics 20090901

• Subcutaneous infusion of esomeprazole in elderly patients in palliative care: a report of two cases.

  Journal of the American Geriatrics Society 20090901

• Off-label use of medicines in children: can available evidence avoid useless paediatric trials? The case of proton pump inhibitors for the treatment of gastroesophageal reflux disease.

  European journal of clinical pharmacology 20090801

• Pharmacodynamics and systemic exposure of esomeprazole in preterm infants and term neonates with gastroesophageal reflux disease.

  The Journal of pediatrics 20090801

• Esomeprazole for asthma.

  The New England journal of medicine 20090709

• Esomeprazole for asthma.

  The New England journal of medicine 20090709

• Esomeprazole for asthma.

  The New England journal of medicine 20090709

• Second-line levofloxacin-based triple schemes for Helicobacter pylori eradication.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20090701

• Transmucosal gastric leak induced by proton pump inhibitors.

  Digestive diseases and sciences 20090701

• Microscopic colitis associated with omeprazole and esomeprazole exposure.

  Journal of clinical gastroenterology 20090701

• Proton-pump inhibitor therapy induces acid-related symptoms in healthy volunteers after withdrawal of therapy.

  Gastroenterology 20090701

• H. pylori eradication prevents the progression of gastric intestinal metaplasia in reflux esophagitis patients using long-term esomeprazole.

  The American journal of gastroenterology 20090701

• Clinical trial: intragastric acid control in patients who have Barrett's oesophagus--comparison of once- and twice-daily regimens of esomeprazole and lansoprazole.

  Alimentary pharmacology & therapeutics 20090701

• Clinical course of laryngo-respiratory symptoms in gastro-oesophageal reflux disease during routine care--a 5-year follow-up.

  Alimentary pharmacology & therapeutics 20090601

• Characterization of mechanisms underlying the effects of esomeprazole on the impairment of gastric ulcer healing with addition of NSAID treatment.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20090601

• Clinical trial: factors associated with freedom from relapse of heartburn in patients with healed reflux oesophagitis--results from the maintenance phase of the EXPO study.

  Alimentary pharmacology & therapeutics 20090601

• Clinical trial: the treatment of gastro-oesophageal reflux disease in primary care--prospective randomized comparison of rabeprazole 20 mg with esomeprazole 20 and 40 mg.

  Alimentary pharmacology & therapeutics 20090501

• Clinical trial: factors associated with resolution of heartburn in patients with reflux oesophagitis--results from the EXPO study.

  Alimentary pharmacology & therapeutics 20090501

• Efficacy of levofloxacin-based rescue therapy for Helicobacter pylori infection after standard triple therapy: a randomized controlled trial.

  The Journal of antimicrobial chemotherapy 20090501

• Hypomagnesaemia due to use of proton pump inhibitors--a review.

  The Netherlands journal of medicine 20090501

• Effect of proton pump inhibition on the gastric volume: assessed by magnetic resonance imaging.

  Alimentary pharmacology & therapeutics 20090415

• Efficacy of esomeprazole for treatment of poorly controlled asthma.

  The New England journal of medicine 20090409

• Intravenous esomeprazole for prevention of recurrent peptic ulcer bleeding: a randomized trial.

  Annals of internal medicine 20090407

• Impact of proton pump inhibitors on the antiplatelet effects of clopidogrel.

  Thrombosis and haemostasis 20090401

• Is body mass index really the most important factor determining the healing of reflux esophagitis by esomeprazole?

  The American journal of gastroenterology 20090301

• Seven-day PPI-triple therapy with levofloxacin is very effective for Helicobacter pylori eradication.

  The Netherlands journal of medicine 20090301

• Oral or intravenous proton pump inhibitor in patients with peptic ulcer bleeding after successful endoscopic epinephrine injection.

  British journal of clinical pharmacology 20090301

• Comparative study of omeprazole, lansoprazole, pantoprazole and esomeprazole for symptom relief in patients with reflux esophagitis.

  World journal of gastroenterology 20090227

• Nefopam hydrochloride compatibility and stability with selected proton pump inhibitors in bionolyte G5 injection for intravenous infusion.

  Journal of clinical pharmacy and therapeutics 20090201

• Esomeprazole: a proton pump inhibitor.

  Expert review of gastroenterology & hepatology 20090201

• After move to tier 3, Nexium scripts fall 25%.

  Managed care (Langhorne, Pa.) 20090201

• Release of regulatory gut peptides somatostatin, neurotensin and vasoactive intestinal peptide by acid and hyperosmolal solutions in the intestine in conscious rats.

  Regulatory peptides 20090108

• A randomized, open trial evaluating the effect of Saccharomyces boulardii on the eradication rate of Helicobacter pylori infection in children.

  Acta paediatrica (Oslo, Norway : 1992) 20090101

• Optimal dose regimens of esomeprazole for gastric acid suppression with minimal influence of the CYP2C19 polymorphism.

  European journal of clinical pharmacology 20090101

• Cost analysis of long-term treatment of patients with symptomatic gastroesophageal reflux disease (GERD) with esomeprazole on-demand treatment or esomeprazole continuous treatment: an open, randomized, multicenter study in Switzerland.

  Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20090101

• Effects of pantoprazole and esomeprazole on platelet inhibition by clopidogrel.

  American heart journal 20090101

• The Australian rise of esomeprazole-was expenditure on samples a contributor?

  Pharmacoepidemiology and drug safety 20090101

• Proton-pump inhibitor utilization associated with the change to nonpreferred formulary status for esomeprazole in the TRICARE formulary.

  Journal of managed care pharmacy : JMCP 20090101

• Chemoprevention of oesophageal cancer and the AspECT trial.

  Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20090101

• Alternative vs. conventional treatment given on-demand for gastroesophageal reflux disease: a randomised controlled trial.

  BMC complementary and alternative medicine 20090101

• [Stevens-Johnson syndrome and toxic hepatitis due to esomeprazole].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20090101

• Improving quality of magnetic resonance cholangiopancreaticography: esomeprazole versus ranitidine.

  Hepato-gastroenterology 20090101

• High-dose esomeprazole for treatment of symptomatic refractory gastroesophageal reflux disease--a prospective pH-metry/impedance-controlled study.

  Digestion 20090101

• Esomeprazole for the management of upper gastrointestinal symptoms in patients who require NSAIDs: a review of the NASA and SPACE double-blind, placebo-controlled studies.

  Clinical drug investigation 20090101

• Patient satisfaction with switching to esomeprazole from existing proton pump inhibitor therapy for gastro-oesophageal reflux disease: an observational, multicentre study.

  Clinical drug investigation 20090101

• [Esomeprazole based triple therapy for the eradication of helicobacter pylori in patients with non-ulcer dyspepsia].

  Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru 20090101

• Effects of esomeprazole treatment for gastroesophageal reflux disease on quality of life in 12- to 17-year-old adolescents: an international health outcomes study.

  BMC gastroenterology 20090101

• [Omeprazol and ezomeprazol pharmacokinetics, duration of antisecretory effect, and reasons for their probable changes in duodenal ulcer].

  Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20090101

• Peptic ulcer bleeding following therapeutic endoscopy: a new indication for intravenous esomeprazole.

  Reviews in gastroenterological disorders 20090101

• [Usage of Nexium (ezomeprazole) at children with acid depended inflammatory diseases of upper gastrointestinal tract].

  Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20090101

• [Comparative study of esomeprazole and omeprazole using for initialism therapy for elderly-senile and young-adulthood patients with GERD].

  Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20090101

• Moxifloxacine plus amoxicillin and ranitidine bismuth citrate or esomeprazole triple therapies for Helicobacter pylori infection.

  Digestive diseases and sciences 20081201

• A glass of water immediately increases gastric pH in healthy subjects.

  Digestive diseases and sciences 20081201

• Esomeprazole induces upper gastrointestinal tract transmucosal permeability increase.

  Alimentary pharmacology & therapeutics 20081201

• Effect of CYP2C19 genetic polymorphisms on the efficacy of proton pump inhibitor-based triple therapy for Helicobacter pylori eradication: a meta-analysis.

  Helicobacter 20081201

• The effectiveness of esomeprazole 40 mg in patients with persistent symptoms of gastro-oesophageal reflux disease following treatment with a full dose proton pump inhibitor.

  International journal of clinical practice 20081201

• [Chronic use of proton-pump inhibitors associated with giardiasis: A rare cause of hypomagnesemic hypoparathyroidism?].

  Annales d'endocrinologie 20081101

• Bravo capsule system optimizes intragastric pH monitoring over prolonged time: effects of ghrelin on gastric acid and hormone secretion in the rat.

  World journal of gastroenterology 20081028

• [General practitioners' management of gastroesophageal reflux in France in 2005: a pharmacoeconomic study].

  Presse medicale (Paris, France : 1983) 20081001

• Effects of esomeprazole on glutathione levels and mitochondrial oxidative phosphorylation in the gastric mucosa of rats treated with indomethacin.

  Naunyn-Schmiedeberg's archives of pharmacology 20081001

• Efficacy of esomeprazole (20 mg once daily) for reducing the risk of gastroduodenal ulcers associated with continuous use of low-dose aspirin.

  The American journal of gastroenterology 20081001

• Meta-analysis: high-dose proton pump inhibitors vs. standard dose in triple therapy for Helicobacter pylori eradication.

  Alimentary pharmacology & therapeutics 20081001

• Medical or surgical management of GERD patients with Barrett's esophagus: the LOTUS trial 3-year experience.

  Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20081001

• Comparing laparoscopic antireflux surgery with esomeprazole in the management of patients with chronic gastro-oesophageal reflux disease: a 3-year interim analysis of the LOTUS trial.

  Gut 20080901

• Physical and chemical stability of esomeprazole sodium solutions.

  The Annals of pharmacotherapy 20080901

• Body mass index can determine the healing of reflux esophagitis with Los Angeles Grades C and D by esomeprazole.

  The American journal of gastroenterology 20080901

• Double-blind, placebo-controlled trial with esomeprazole for symptoms and signs associated with laryngopharyngeal reflux.

  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20080901

• Preparation of esomeprazole zinc solid dispersion and study on its pharmacokinetics.

  International journal of pharmaceutics 20080806

• Effect of the CYP2C19 polymorphism on the eradication rate of Helicobacter pylori infection by 7-day triple therapy with regular proton pump inhibitor dosage.

  Journal of gastroenterology and hepatology 20080801

• [Comparison of Helicobacter pylori eradication rate in patients with non-ulcer dyspepsia and peptic ulcer diseases according to proton pump inhibitors].

  The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20080801

• Predictable prolonged suppression of gastric acidity with a novel proton pump inhibitor, AGN 201904-Z.

  Alimentary pharmacology & therapeutics 20080701

• Changes in gene expression of gastric mucosa during therapeutic acid inhibition.

  European journal of gastroenterology & hepatology 20080701

• [Preparation and dissolution in vitro of esomeprazole zinc solid dispersion].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20080701

• Effect of esomeprazole triple therapy on eradication rates of Helicobacter pylori, gastric ulcer healing and prevention of relapse in gastric ulcer patients.

  European journal of gastroenterology & hepatology 20080601

• Esomeprazole in acute and maintenance treatment of reflux oesophagitis: a multicentre prospective study.

  Advances in therapy 20080601

• [Diagnosis of gastroesophageal reflux disease-related noncardiac chest pain].

  Zhonghua yi xue za zhi 20080527

• The effect of famotidine, esomeprazole, and ezetimibe on levothyroxine absorption.

  Thyroid : official journal of the American Thyroid Association 20080501

• FDA approves nexium for use in children ages 1-11 years.

  Gastroenterology 20080501

• Safety and tolerability of esomeprazole in children with gastroesophageal reflux disease.

  Journal of pediatric gastroenterology and nutrition 20080501

• Preoperative administration of esomeprazole has no influence on frequency of refluxes.

  Journal of clinical anesthesia 20080501

• Intravenous esomeprazole for prevention of peptic ulcer re-bleeding: rationale/design of Peptic Ulcer Bleed study.

  Alimentary pharmacology & therapeutics 20080401

• Correlation between oesophageal acid exposure and dyspeptic symptoms in patients with nonerosive reflux disease.

  European journal of gastroenterology & hepatology 20080401

• Comparison of esomeprazole enteric-coated capsules vs esomeprazole magnesium in the treatment of active duodenal ulcer: a randomized, double-blind, controlled study.

  World journal of gastroenterology 20080328

• Intravenous esomeprazole 40 mg vs. intravenous lansoprazole 30 mg for controlling intragastric acidity in healthy adults.

  Alimentary pharmacology & therapeutics 20080315

• The anti-secretory and anti-ulcer activities of esomeprazole in comparison with omeprazole in the stomach of rats and rabbits.

  Molecular and cellular biochemistry 20080201

• One-week once-daily triple therapy with esomeprazole, moxifloxacin, and rifabutin for eradication of persistent Helicobacter pylori resistant to both metronidazole and clarithromycin.

  Helicobacter 20080201

• In-practice predictors of response to proton pump inhibitor therapy in primary care patients with dyspepsia in an Asian population.

  Journal of clinical gastroenterology 20080201

• Management strategy for patients with gastroesophageal reflux disease: a comparison between empirical treatment with esomeprazole and endoscopy-oriented treatment.

  The American journal of gastroenterology 20080201

• A randomized, comparative trial of a potassium-competitive acid blocker (AZD0865) and esomeprazole for the treatment of patients with nonerosive reflux disease.

  The American journal of gastroenterology 20080101

• Validation of a four-graded scale for severity of heartburn in patients with symptoms of gastroesophageal reflux disease.

  Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20080101

• Clinical efficacy of esomeprazole in the prevention and healing of gastrointestinal toxicity associated with NSAIDs in elderly patients.

  Drugs & aging 20080101

• Effect of proton-pump inhibitor treatment on symptoms and quality of life in GERD patients depends on the symptom-reflux association.

  Journal of clinical gastroenterology 20080101

• Safety profile of esomeprazole: results of a prescription-event monitoring study of 11 595 patients in England.

  Drug safety 20080101

• Stereoselective disposition of proton pump inhibitors.

  Clinical drug investigation 20080101

• Esomeprazole: in gastroesophageal reflux disease in children and adolescents.

  Paediatric drugs 20080101

• Effect of increasing esomeprazole and pantoprazole doses on acid control in patients with symptoms of gastro-oesophageal reflux disease: a randomized, dose-response study.

  Clinical drug investigation 20080101

• Occurrence of community-acquired respiratory tract infection in patients receiving esomeprazole: retrospective analysis of adverse events in 31 clinical trials.

  Drug safety 20080101

• Esomeprazole: a review of its use in the management of gastric acid-related diseases in adults.

  Drugs 20080101

• Effect of acid suppression on gastric myoelectrical activity in GERD.

  Hepato-gastroenterology 20080101

• Esomeprazole reduces gastroesophageal reflux after beer consumption in healthy volunteers.

  Scandinavian journal of gastroenterology 20080101

• Effect of proton pump inhibitors on gastric juice volume, gastric pH and gastric intramucosal pH in critically ill patients : a randomized, double-blind, placebo-controlled study.

  Clinical drug investigation 20080101

• The effect of acid suppression on sleep and cardiac autonomic regulation in GERD.

  Hepato-gastroenterology 20080101

• Esomeprazole prevents aspirin-induced ulcers.

  Medscape journal of medicine 20080101

• Effects of esomeprazole on acid output in patients with Zollinger-Ellison syndrome or idiopathic gastric acid hypersecretion.

  The American journal of gastroenterology 20071201

• Water load test before and after PPI therapy in patients with gastro-oesophageal reflux disease.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20071201

• A randomized, comparative study of three doses of AZD0865 and esomeprazole for healing of reflux esophagitis.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20071201

• Second-line treatment for Helicobacter pylori infection: 10-day moxifloxacin-based triple therapy versus 2-week quadruple therapy.

  Helicobacter 20071201

• Rabeprazole- versus esomeprazole-based eradication regimens for H. pylori infection.

  Helicobacter 20071201

• Double-dose, new-generation proton pump inhibitors do not improve Helicobacter pylori eradication rate.

  Helicobacter 20071201

• Esomeprazole-induced DRESS syndrome. Studies of cross-reactivity among proton-pump inhibitor drugs.

  Allergy 20071101

• The impact of body mass index on the application of on-demand therapy for Los Angeles grades A and B reflux esophagitis.

  The American journal of gastroenterology 20071101

• Safety and symptom improvement with esomeprazole in adolescents with gastroesophageal reflux disease.

  Journal of pediatric gastroenterology and nutrition 20071101

• Pharmacokinetics and acid-suppressive effects of esomeprazole in infants 1-24 months old with symptoms of gastroesophageal reflux disease.

  Journal of pediatric gastroenterology and nutrition 20071101

• Impact of treatment of gastroesophageal reflux on obstructive sleep apnea-hypopnea syndrome.

  The Annals of otology, rhinology, and laryngology 20071101

• Clinical trial: healing of NSAID-associated gastric ulcers in patients continuing NSAID therapy - a randomized study comparing ranitidine with esomeprazole.

  Alimentary pharmacology & therapeutics 20071015

• [Repeated dual-probe pH monitoring as a diagnostic tool to control therapy for laryngopharyngeal reflux].

  HNO 20071001

• Clinical trial: levofloxacin-based quadruple therapy was inferior to traditional quadruple therapy in the treatment of resistant Helicobacter pylori infection.

  Alimentary pharmacology & therapeutics 20071001

• Effect of timing of dosing in relation to food intake on the pharmacokinetics of esomeprazole.

  British journal of clinical pharmacology 20070901

• High-dose versus low-dose esomeprazole-based triple therapy for Helicobacter pylori infection.

  European journal of clinical investigation 20070901

• One-week acid suppression trial in uninvestigated dyspepsia patients with epigastric pain or burning to predict response to 8 weeks' treatment with esomeprazole: a randomized, placebo-controlled study.

  Alimentary pharmacology & therapeutics 20070901

• Randomized-controlled trial of esomeprazole in functional dyspepsia patients with epigastric pain or burning: does a 1-week trial of acid suppression predict symptom response?

  Alimentary pharmacology & therapeutics 20070901

• Distension during gastroesophageal reflux: effects of acid inhibition and correlation with symptoms.

  American journal of physiology. Gastrointestinal and liver physiology 20070801

• Recent advances in chirally pure proton pump inhibitors.

  Journal of the Indian Medical Association 20070801

• Effect of baseline symptom severity on patient-reported outcomes in gastroesophageal reflux disease.

  European journal of gastroenterology & hepatology 20070701

• A clinical trial comparing pantoprazole and esomeprazole to explore the concept of achieving 'complete remission' in gastro-oesophageal reflux disease.

  Alimentary pharmacology & therapeutics 20070615

• Soraprazan: setting new standards in inhibition of gastric acid secretion.

  The Journal of pharmacology and experimental therapeutics 20070601

• One week of esomeprazole triple therapy vs 1 week of omeprazole triple therapy plus 3 weeks of omeprazole for duodenal ulcer healding in Helicobacter pylori-positive patients.

  Digestive diseases and sciences 20070601

• Tegaserod for dyspepsia and reflux symptoms in patients with chronic constipation: an exploratory open-label study.

  European journal of clinical pharmacology 20070601

• Severe systemic adverse reaction to proton pump inhibitors in an infant.

  Pediatric pulmonology 20070601

• Effect of esomeprazole and rabeprazole on intragastric pH in healthy Chinese: an open, randomized crossover trial.

  Journal of gastroenterology and hepatology 20070601

• [Protonic pump inhibitors in kidney transplant patients: efficacy and safety].

  Minerva urologica e nefrologica = The Italian journal of urology and nephrology 20070601

• [Different courses of esomeprazole-based triple therapy for Helicobactor pylori infection in children].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20070601

• Suppression of gastric acid with intravenous esomeprazole and omeprazole: results of 3 studies in healthy subjects.

  International journal of clinical pharmacology and therapeutics 20070601

• Combination of a cyclo-oxygenase-2 inhibitor and a proton-pump inhibitor for prevention of recurrent ulcer bleeding in patients at very high risk: a double-blind, randomised trial.

  Lancet (London, England) 20070512

• Helicobacter pylori eradication: a randomized prospective study of triple therapy versus triple therapy plus lactoferrin and probiotics.

  The American journal of gastroenterology 20070501

• Symptom overlap in patients with upper gastrointestinal complaints in the Canadian confirmatory acid suppression test (CAST) study: further psychometric validation of the reflux disease questionnaire.

  Alimentary pharmacology & therapeutics 20070501

• Esomeprazole: prevention and treatment of NSAID-induced symptoms and ulcers.

  Expert opinion on pharmacotherapy 20070501

• Determination of esomeprazole and its two main metabolites in human, rat and dog plasma by liquid chromatography with tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070401

• Efficacy of esomeprazole for resolution of symptoms of heartburn and acid regurgitation in continuous users of non-steroidal anti-inflammatory drugs.

  Alimentary pharmacology & therapeutics 20070401

• Effect of lactoferrin supplementation on the effectiveness and tolerability of a 7-day quadruple therapy after failure of a first attempt to cure Helicobacter pylori infection.

  Medical science monitor : international medical journal of experimental and clinical research 20070401

• A new esomeprazole packet (sachet) formulation for suspension: in vitro characteristics and comparative pharmacokinetics versus intact capsules/tablets in healthy volunteers.

  Clinical therapeutics 20070401

• [Clinical pharmacological aspects of the proton pump inhibitor therapy: importance of pharmacogenetic differences in the clinical practice].

  Orvosi hetilap 20070325

• Efficacy of pantoprazole 20 mg daily compared with esomeprazole 20 mg daily in the maintenance of healed gastroesophageal reflux disease: a randomized, double-blind comparative trial - the EMANCIPATE study.

  European journal of gastroenterology & hepatology 20070301

• Relationship between intragastric acid control and healing status in the treatment of moderate to severe erosive oesophagitis.

  Alimentary pharmacology & therapeutics 20070301

• Effect of antireflux treatment on asthma exacerbations in nonatopic children.

  Journal of pediatric gastroenterology and nutrition 20070301

• Use of intravenous immunoglobulin for the treatment of severe Clostridium difficile colitis.

  The American journal of geriatric pharmacotherapy 20070301

• Combined analysis of three crossover clinical pharmacology studies of effects of rabeprazole and esomeprazole on 24-h intragastric pH in healthy volunteers.

  Alimentary pharmacology & therapeutics 20070215

• [Changes of intercellular spaces of esophageal epithelium in patients with gastroesophageal reflux disease before and after esomeprazole treatment].

  Zhonghua yi xue za zhi 20070206

• Does esomeprazole prevent post-operative nausea and vomiting?

  Acta anaesthesiologica Scandinavica 20070201

• Effect of intravenous application of esomeprazole 40 mg versus pantoprazole 40 mg on 24-hour intragastric pH in healthy adults.

  European journal of gastroenterology & hepatology 20070201

• Efficacy of once-daily esomeprazole treatment in patients with laryngopharyngeal reflux evaluated by 24-hour pH monitoring.

  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20070201

• Acidic and non-acidic reflux during sleep under conditions of powerful acid suppression.

  Chest 20070201

• Acid control with esomeprazole and lansoprazole: a comparative dose-response study.

  Scandinavian journal of gastroenterology 20070201

• [Proton pump inhibitors in developmental period medicine].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20070201

• Comparison of the effects of immediate-release omeprazole oral suspension, delayed-release lansoprazole capsules and delayed-release esomeprazole capsules on nocturnal gastric acidity after bedtime dosing in patients with night-time GERD symptoms.

  Alimentary pharmacology & therapeutics 20070115

• Effect of oral esomeprazole on recurrent bleeding after endoscopic treatment of bleeding peptic ulcers.

  Journal of gastroenterology and hepatology 20070101

• Maintenance treatment with esomeprazole following initial relief of non-steroidal anti-inflammatory drug-associated upper gastrointestinal symptoms: the NASA2 and SPACE2 studies.

  Arthritis research & therapy 20070101

• Novel measurement of rapid treatment success with ReQuest: first and sustained symptom relief as outcome parameters in patients with endoscopy-negative GERD receiving 20 mg pantoprazole or 20 mg esomeprazole.

  Digestion 20070101

• Pantoprazole 40 mg is as effective as esomeprazole 40 mg to relieve symptoms of gastroesophageal reflux disease after 4 weeks of treatment and superior regarding the prevention of symptomatic relapse.

  Digestion 20070101

• Bioequivalence study of a sustained release fixed dose combination capsule containing esomeprazole and domperidone in healthy subjects.

  Arzneimittel-Forschung 20070101

• Symptom resolution does not predict healing of erosive oesophagitis in Chinese.

  Digestion 20070101

• The concept of complete remission of gastro-oesophageal reflux disease : comparative efficacy of pantoprazole and esomeprazole using the ReQuest questionnaire.

  Clinical drug investigation 20070101

• Potential options to optimize therapy of gastroesophageal reflux disease with proton pump inhibitors.

  Digestion 20070101

• Effect of intravenous esomeprazole 40 mg and pantoprazole 40 mg on intragastric pH in healthy subjects. A prospective, open, randomised, two-way cross-over comparative study.

  Arzneimittel-Forschung 20070101

• [Efficiency and safety of the intravenous application of esomeprazole (nexium - Astra Zeneca) in high risk patients subjected to mechanic ventilation].

  Khirurgiia 20070101

• Esomeprazole versus other proton pump inhibitors in erosive esophagitis: a meta-analysis of randomized clinical trials.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20061201

• An in vitro comparison of different providers to deliver four proton pump inhibitor products through a feeding tube.

  Alimentary pharmacology & therapeutics 20061201

• [Antiplatelet therapy after aspirin-induced upper gastrointestinal bleeding].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20061102

• Prospective follow-up data from the ProGERD study suggest that GERD is not a categorial disease.

  The American journal of gastroenterology 20061101

• Randomized comparison of two rescue therapies for Helicobacter pylori infection.

  European journal of clinical investigation 20061101

• Pharmacokinetic properties of esomeprazole in children aged 1 to 11 years with symptoms of gastroesophageal reflux disease: a randomized, open-label study.

  Clinical therapeutics 20061101

• Delivery of esomeprazole magnesium through nasogastric and gastrostomy tubes using an oral liquid vehicle as a suspending agent in vitro.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20061001

• Esomeprazole 40 mg once a day in patients with functional dyspepsia: the randomized, placebo-controlled 'ENTER' trial.

  The American journal of gastroenterology 20060901

• Gastric and esophageal pH in patients with Barrett's esophagus treated with three esomeprazole dosages: a randomized, double-blind, crossover trial.

  The American journal of gastroenterology 20060901

• Effects of single doses of rabeprazole 20 mg and esomeprazole 40 mg on 24-h intragastric pH in healthy subjects.

  European journal of clinical pharmacology 20060901

• Systematic review: proton pump inhibitors (PPIs) for the healing of reflux oesophagitis - a comparison of esomeprazole with other PPIs.

  Alimentary pharmacology & therapeutics 20060901

• Sequential therapy using high-dose esomeprazole-amoxicillin followed by gatifloxacin for Helicobacter pylori infection.

  Alimentary pharmacology & therapeutics 20060901

• Treatment of chronic posterior laryngitis with esomeprazole.

  The Laryngoscope 20060901

• Levofloxacin-based triple therapy in first-line treatment for Helicobacter pylori eradication.

  The American journal of gastroenterology 20060901

• Esomeprazole versus pantoprazole for healing erosive oesophagitis.

  Collegium antropologicum 20060901

• Ablation of nonneoplastic Barrett's mucosa using argon plasma coagulation with concomitant esomeprazole therapy (APBANEX): a prospective multicenter evaluation.

  The American journal of gastroenterology 20060801

• Esomeprazole-based 1-week triple therapy directed by susceptibility testing for eradication of Helicobacter pylori infection in children.

  Journal of pediatric gastroenterology and nutrition 20060801

• Role of the preliminary susceptibility testing for initial and after failed therapy of Helicobacter pylori infection with levofloxacin, amoxicillin, and esomeprazole.

  Helicobacter 20060801

• Randomized trial of rifabutin-based triple therapy and high-dose dual therapy for rescue treatment of Helicobacter pylori resistant to both metronidazole and clarithromycin.

  Alimentary pharmacology & therapeutics 20060715

• Maintenance of healed erosive esophagitis: a randomized six-month comparison of esomeprazole twenty milligrams with lansoprazole fifteen milligrams.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20060701

• Esomeprazole with aspirin versus clopidogrel for prevention of recurrent gastrointestinal ulcer complications.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20060701

• Clinical impact of CYP2C19 polymorphism on the action of proton pump inhibitors: a review of a special problem.

  International journal of clinical pharmacology and therapeutics 20060701

• Review article: the opportunities and benefits of extended acid suppression.

  Alimentary pharmacology & therapeutics 20060601

• Myopathy including polymyositis: a likely class adverse effect of proton pump inhibitors?

  European journal of clinical pharmacology 20060601

• Eradication of Helicobacter pylori and dosages of esomeprazole.

  The American journal of gastroenterology 20060601

• Effects of esomeprazole 40 mg twice daily on asthma: a randomized placebo-controlled trial.

  American journal of respiratory and critical care medicine 20060515

• Coadministration of esomeprazole with fosamprenavir has no impact on steady-state plasma amprenavir pharmacokinetics.

  Journal of acquired immune deficiency syndromes (1999) 20060501

• A multicenter, randomized, double-blind, 8-week comparative trial of standard doses of esomeprazole (40 mg) and omeprazole (20 mg) for the treatment of erosive esophagitis.

  Digestive diseases and sciences 20060501

• A multicenter, randomized, double-blind, 8-week comparative trial of low-dose esomeprazole (20 mg) and standard-dose omeprazole (20 mg) in patients with erosive esophagitis.

  Digestive diseases and sciences 20060501

• Intragastric acidity after switching from 5-day treatment with intravenous pantoprazole 40 mg/d to 5-day treatment with oral esomeprazole 40 mg/d or pantoprazole 40 mg/d: an open-label crossover study in healthy adult volunteers.

  Clinical therapeutics 20060501

• Intragastric acid control in non-steroidal anti-inflammatory drug users: comparison of esomeprazole, lansoprazole and pantoprazole.

  Alimentary pharmacology & therapeutics 20060415

• Bovine lactoferrin for Helicobacter pylori eradication: an open, randomized, multicentre study.

  Alimentary pharmacology & therapeutics 20060415

• Esomeprazole for the prevention of postoperative nausea and vomiting. A randomized, placebo-controlled trial.

  European journal of anaesthesiology 20060401

• Prevention of ulcers by esomeprazole in at-risk patients using non-selective NSAIDs and COX-2 inhibitors.

  The American journal of gastroenterology 20060401

• Effects of esomeprazole on the pharmacokinetics of atazanavir and fosamprenavir in a patient with human immunodeficiency virus infection.

  Pharmacotherapy 20060401

• The effects of esomeprazole combined with aspirin or rofecoxib on prostaglandin E2 production in patients with Barrett's oesophagus.

  Alimentary pharmacology & therapeutics 20060401

• A COX-2-specific inhibitor plus a proton-pump inhibitor: is this a reasonable approach to reduction in NSAIDs' GI toxicity?

  The American journal of gastroenterology 20060401

• [Long-term treatment of patients with symptomatic gastroesophageal reflux disease comparing costs and efficacy over 6 months of treatment with Nexium On-Demand Treatment or Nexium continuous treatment. An open, randomised multi-center study].

  Praxis 20060329

• Studies on drug interactions between esomeprazole, amoxicillin and clarithromycin in healthy subjects.

  International journal of clinical pharmacology and therapeutics 20060301

• Pharmacokinetic properties of esomeprazole in adolescent patients aged 12 to 17 years with symptoms of gastroesophageal reflux disease: A randomized, open-label study.

  Clinical therapeutics 20060301

• Validation of a symptom diary for patients with gastro-oesophageal reflux disease.

  Alimentary pharmacology & therapeutics 20060215

• Sensitive quantification of omeprazole and its metabolites in human plasma by liquid chromatography-mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060202

• Intra-oesophageal acid suppression in complicated gastro-oesophageal reflux disease: esomeprazole versus lansoprazole.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20060201

• Upper gastrointestinal haemorrhage complicating antiplatelet treatment with aspirin and/or clopidogrel: where we are now?

  Platelets 20060201

• 7-day triple therapy of Helicobacter pylori infection with levofloxacin, amoxicillin, and high-dose esomeprazole in patients with known antimicrobial sensitivity.

  Helicobacter 20060201

• Efficacy of moxifloxacin-based triple therapy as second-line treatment for Helicobacter pylori infection.

  Helicobacter 20060201

• Twice-a-day quadruple therapy for eradication of Helicobacter pylori in the elderly.

  Helicobacter 20060201

• Treatment of chronic posterior laryngitis with esomeprazole.

  The Laryngoscope 20060201

• Helicobacter pylori eradication with either 7-day or 10-day triple therapies, and with a 10-day sequential regimen.

  Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20060201

• Histological effects of esomeprazole therapy on the squamous epithelium of the distal oesophagus.

  Alimentary pharmacology & therapeutics 20060115

• Long-term management of patients with symptoms of gastro-oesophageal reflux disease -- a Norwegian randomised prospective study comparing the effects of esomeprazole and ranitidine treatment strategies on health-related quality of life in a general practitioners setting.

  International journal of clinical practice 20060101

• Treatment of patients with persistent heartburn symptoms: a double-blind, randomized trial.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20060101

• Intravenous proton pump inhibitors.

  Reviews in gastroenterological disorders 20060101

• [Economic evaluation of the treatment with aspirin plus esomeprazole compared to clopidogrel in gastrointestinal bleeding prevention].

  Gaceta sanitaria 20060101

• Rifaximin-based regimens for eradication of Helicobacter pylori: a pilot study.

  Digestive diseases (Basel, Switzerland) 20060101

• A meta-analysis: comparison of esomeprazole and other proton pump inhibitors in eradicating Helicobacter pylori.

  Digestion 20060101

• Atypical symptoms of GORD in Belgium: epidemiological features, current management and open label treatment with 40 mg esomeprazole for one month.

  Acta gastro-enterologica Belgica 20060101

• Pharmacokinetic drug interaction profiles of proton pump inhibitors.

  Drug safety 20060101

• Comparative study of modified-release clarithromycin and immediate-release clarithromycin in the treatment of Helicobacter pylori-associated peptic ulcer disease.

  Hepato-gastroenterology 20060101

• Pantoprazole 40 mg is as effective as esomeprazole 40 mg to relieve symptoms of gastroesophageal reflux disease after 4 weeks of treatment and superior regarding the prevention of symptomatic relapse.

  Digestion 20060101

• Diagnostic value of the Reflux Disease Questionnaire in general practice.

  Digestion 20060101

• Esomeprazole therapy for gastric acid hypersecretion in children with cystinosis.

  Pediatric nephrology (Berlin, Germany) 20051201

• [ASS or clopidogrel plus esomeprazole after bleeding from an ulcer].

  Der Internist 20051201

• Esomeprazole-induced healing of gastroesophageal reflux disease is unrelated to the genotype of CYP2C19: evidence from clinical and pharmacokinetic data.

  Clinical pharmacology and therapeutics 20051201

• Pharmacokinetics of esomeprazole following varying intravenous administration rates.

  Basic & clinical pharmacology & toxicology 20051201

• Healing of gastric ulcers with esomeprazole versus ranitidine in patients who continued to receive NSAID therapy: a randomized trial.

  The American journal of gastroenterology 20051201

• Esomeprazole 20 mg vs. pantoprazole 20 mg for maintenance therapy of healed erosive oesophagitis: results from the EXPO study.

  Alimentary pharmacology & therapeutics 20051101

• Comparison of the effects of intravenously and orally administered esomeprazole on acid output in patients with symptoms of gastro-oesophageal reflux disease.

  Alimentary pharmacology & therapeutics 20051101

• Gastric fundal polyps with cellular atypia in a patient using esomeprazole (Nexium).

  Digestive diseases and sciences 20051101

• A prospective randomized trial of esomeprazole- versus pantoprazole-based triple therapy for Helicobacter pylori eradication.

  The American journal of gastroenterology 20051101

• [Cytolytic hepatitis and esomeprazole during chemotherapy].

  Presse medicale (Paris, France : 1983) 20051008

• Comment: esomeprazole-induced central fever with severe myalgia.

  The Annals of pharmacotherapy 20051001

• Cost-effectiveness comparison of current proton-pump inhibitors to treat gastro-oesophageal reflux disease in the UK.

  Current medical research and opinion 20051001

• Effect of esomeprazole on nighttime heartburn and sleep quality in patients with GERD: a randomized, placebo-controlled trial.

  The American journal of gastroenterology 20050901

• Esomeprazole-based therapy in Helicobacter pylori eradication: any effect by increasing the dose of esomeprazole or prolonging the treatment?

  The American journal of gastroenterology 20050901

• Effect on intragastric pH of a PPI with a prolonged plasma half-life: comparison between tenatoprazole and esomeprazole on the duration of acid suppression in healthy male volunteers.

  The American journal of gastroenterology 20050901

• Quality of life in acute and maintenance treatment of non-erosive and mild erosive gastro-oesophageal reflux disease.

  Alimentary pharmacology & therapeutics 20050815

• Long-term omeprazole and esomeprazole treatment does not significantly increase gastric epithelial cell proliferation and epithelial growth factor receptor expression and has no effect on apoptosis and p53 expression.

  World journal of gastroenterology 20050814

• Comparative study and optimisation of the administration mode of three proton pump inhibitors by nasogastric tube.

  International journal of pharmaceutics 20050811

• One-week once-daily triple therapy with esomeprazole, levofloxacin and azithromycin compared to a standard therapy for Helicobacter pylori eradication.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20050801

• Daily treatment with esomeprazole is superior to that taken on-demand for maintenance of healed erosive oesophagitis.

  Alimentary pharmacology & therapeutics 20050801

• [Comparison of esomeprazole- and omeprazole-based triple therapy regimens for duodenal ulcer with Helicobacter pylori infection].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050801

• A comparison of esomeprazole and lansoprazole for control of intragastric pH in patients with symptoms of gastro-oesophageal reflux disease.

  Alimentary pharmacology & therapeutics 20050715

• Laryngopharyngeal reflux: prospective cohort study evaluating optimal dose of proton-pump inhibitor therapy and pretherapy predictors of response.

  The Laryngoscope 20050701

• Prognostic influence of Barrett's oesophagus and Helicobacter pylori infection on healing of erosive gastro-oesophageal reflux disease (GORD) and symptom resolution in non-erosive GORD: report from the ProGORD study.

  Gut 20050601

• Six-month management of patients following treatment for gastroesophageal reflux disease symptoms -- a Norwegian randomized, prospective study comparing the costs and effectiveness of esomeprazole and ranitidine treatment strategies in a general medical practitioners setting.

  International journal of clinical practice 20050601

• A randomised prospective study comparing the effectiveness of esomeprazole treatment strategies in clinical practice for 6 months in the management of patients with symptoms of gastroesophageal reflux disease.

  International journal of clinical practice 20050601

• Empirical treatment for the management of patients presenting with uninvestigated reflux symptoms: a prospective study in an Asian primary care population.

  Alimentary pharmacology & therapeutics 20050601

• [Cacosmia related to therapy with esomeprazole].

  La Revue de medecine interne 20050601

• Influence of CYP2C19 pharmacogenetic polymorphism on proton pump inhibitor-based therapies.

  Drug metabolism and pharmacokinetics 20050601

• Rabeprazole vs esomeprazole in non-erosive gastro-esophageal reflux disease: a randomized, double-blind study in urban Asia.

  World journal of gastroenterology 20050528

• Esomeprazole tablet vs omeprazole capsule in treating erosive esophagitis.

  World journal of gastroenterology 20050528

• Lexiva: blood levels not lowered when taken simultaneously with Nexium.

  AIDS treatment news 20050527

• Moxifloxacin-based strategies for first-line treatment of Helicobacter pylori infection.

  Alimentary pharmacology & therapeutics 20050515

• Improvements with esomeprazole in patients with upper gastrointestinal symptoms taking non-steroidal antiinflammatory drugs, including selective COX-2 inhibitors.

  The American journal of gastroenterology 20050501

• Intragastric acidity during treatment with esomeprazole 40 mg twice daily or pantoprazole 40 mg twice daily--a randomized, two-way crossover study.

  Alimentary pharmacology & therapeutics 20050415

• [Rapidity of pain relief, medication requirement and patient satisfaction with reflux treatment in the physician's office].

  MMW Fortschritte der Medizin 20050407

• Hyponatremia with consciousness disturbance associated with esomeprazole.

  The Annals of pharmacotherapy 20050401

• Esomeprazole-induced central fever with severe myalgia.

  The Annals of pharmacotherapy 20050401

• Efficacy and tolerability of rifampicin-based rescue therapy for Helicobacter pylori eradication failure in peptic ulcer disease.

  Digestive diseases and sciences 20050401

• High eradication rates of Helicobacter pylori infection with first- and second-line combination of esomeprazole, tetracycline, and metronidazole in patients allergic to penicillin.

  Digestive diseases and sciences 20050401

• A randomized comparative study of esomeprazole 40 mg versus pantoprazole 40 mg for healing erosive oesophagitis: the EXPO study.

  Alimentary pharmacology & therapeutics 20050315

• Acute interstitial nephritis secondary to esomeprazole.

  The Medical journal of Australia 20050307

• A comparative study of the early effects of tenatoprazole 40 mg and esomeprazole 40 mg on intragastric pH in healthy volunteers.

  Alimentary pharmacology & therapeutics 20050301

• Esomeprazole in the treatment of patients with heartburn and other upper gastrointestinal symptoms, referred to primary care -- results of the in-practice evaluation program in Romania.

  Romanian journal of gastroenterology 20050301

• Efficacy of esomeprazole 40 mg vs. lansoprazole 30 mg for healing moderate to severe erosive oesophagitis.

  Alimentary pharmacology & therapeutics 20050215

• Intravenous esomeprazole (40 mg and 20 mg) inhibits gastric acid secretion as effectively as oral esomeprazole: results of two randomized clinical studies.

  European journal of gastroenterology & hepatology 20050201

• A randomized controlled trial of equivalence between pantoprazole and esomeprazole that does not have the power to conclude.

  Journal of clinical gastroenterology 20050201

• Esomeprazole 40 mg twice daily in triple therapy and the efficacy of Helicobacter pylori eradication related to CYP2C19 metabolism.

  Alimentary pharmacology & therapeutics 20050201

• [Gastroesophageal reflux disease refractory to esomeprazole].

  Gastroenterologia y hepatologia 20050201

• Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding.

  The New England journal of medicine 20050120

• A pharmacokinetic study comparing single and repeated oral doses of 20 mg and 40 mg omeprazole and its two optical isomers, S-omeprazole (esomeprazole) and R-omeprazole, in healthy subjects.

  European journal of clinical pharmacology 20050101

• Night-time gastro-oesophageal reflux disease: prevalence, hazards, and management.

  European journal of gastroenterology & hepatology 20050101

• The influence of demographic factors and health-related quality of life on treatment satisfaction in patients with gastroesophageal reflux disease treated with esomeprazole.

  Health and quality of life outcomes 20050101

• Esomeprazole MUPS 40 mg tablets and esomeprazole MUPS 40 mg tablets encapsulated in hard gelatine are bioequivalent.

  International journal of clinical pharmacology and therapeutics 20050101

• Effects of esomeprazole magnesium on nonsteroidal anti-inflammatory drug gastropathy.

  Digestive diseases and sciences 20050101

• The influence of gastroesophageal reflux disease and its treatment on asthmatic cough.

  Lung 20050101

• Novel measurement of rapid treatment success with ReQuest: first and sustained symptom relief as outcome parameters in patients with endoscopy-negative GERD receiving 20 mg pantoprazole or 20 mg esomeprazole.

  Digestion 20050101

• Lansoprazole oro-dispersible tablet : pharmacokinetics and therapeutic use in acid-related disorders.

  Drugs 20050101

• The impact of illness in patients with moderate to severe gastro-esophageal reflux disease.

  BMC gastroenterology 20050101

• Comparison of the efficacy of 1-day high-dose quadruple therapy versus 7-day triple therapy for treatment of Helicobacter pylori infection.

  Chinese journal of digestive diseases 20050101

• What is potent acid inhibition, and how can it be achieved?

  Drugs 20050101

• Optimising acid inhibition treatment.

  Drugs 20050101

• Efficacy and safety of intravenous esomeprazole in gastro-esophageal reflux disease and erosive esophagitis in Indian patients.

  Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 20050101

• Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs.

  Journal of the National Cancer Institute 20041117

• Esomeprazole 40 mg i.v. provides faster and more effective intragastric acid control than pantoprazole 40 mg i.v.: results of a randomized study.

  Alimentary pharmacology & therapeutics 20041115

• Review article: pH, healing and symptom relief with rabeprazole treatment in acid-related disorders.

  Alimentary pharmacology & therapeutics 20041101

• Sleep dysfunction in patients with gastro-oesophageal reflux disease: prevalence and response to GERD therapy, a pilot study.

  Alimentary pharmacology & therapeutics 20041101

• Dual-probe 24-hour ambulatory pH monitoring for diagnosis of laryngopharyngeal reflux.

  The Journal of laryngology and otology 20041101

• Esomeprazole 40 mg provides more effective intragastric acid control than lansoprazole 30 mg, omeprazole 20 mg, pantoprazole 40 mg and rabeprazole 20 mg in patients with gastro-oesophageal reflux symptoms.

  European journal of clinical pharmacology 20041001

• Review article: is stringent control of gastric pH useful and practical in GERD?

  Alimentary pharmacology & therapeutics 20041001

• Esomeprazole 20 mg on-demand is more acceptable to patients than continuous lansoprazole 15 mg in the long-term maintenance of endoscopy-negative gastro-oesophageal reflux patients: the COMMAND Study.

  Alimentary pharmacology & therapeutics 20040915

• Therapeutic choices in reflux disease: defining the criteria for selecting a proton pump inhibitor.

  The American journal of medicine 20040906

• Effect of the H, K-ATPase inhibitor, esomeprazole magnesium, on gut total antioxidant capacity in mice.

  The Journal of nutritional biochemistry 20040901

• Intragastric acid suppression and pharmacokinetics of twice-daily esomeprazole: a randomized, three-way crossover study.

  Alimentary pharmacology & therapeutics 20040815

• The role of acid suppression in patients with endoscopy-negative reflux disease: the effect of treatment with esomeprazole or omeprazole.

  Alimentary pharmacology & therapeutics 20040815

• Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities.

  Drug metabolism and disposition: the biological fate of chemicals 20040801

• Symptom response and healing of erosive esophagitis with proton-pump inhibitors in patients with Helicobacter pylori infection.

  The American journal of gastroenterology 20040801

• Esomeprazole versus omeprazole for the eradication of Helicobacter pylori infection: results of a randomized controlled study.

  Journal of clinical gastroenterology 20040701

• Masking of 13C urea breath test by proton pump inhibitors is dependent on type of medication: comparison between omeprazole, pantoprazole, lansoprazole and esomeprazole.

  Alimentary pharmacology & therapeutics 20040701

• [New-generation proton pump inhibitors: progress in the treatment of peptic acid diseases?].

  Presse medicale (Paris, France : 1983) 20040619

• Risk factors of gastroesophageal reflux disease: methodology and first epidemiological results of the ProGERD study.

  Journal of clinical epidemiology 20040601

• Effect of splitting the dose of esomeprazole on gastric acidity and nocturnal acid breakthrough.

  Alimentary pharmacology & therapeutics 20040515

• Effect of proton pump inhibitors and antacid therapy on 13C urea breath tests and stool test for Helicobacter pylori infection.

  The American journal of gastroenterology 20040501

• Induction of testosterone metabolism by esomeprazole in a CYP2C19*2 heterozygote.

  The American journal of the medical sciences 20040501

• Costs and efficacy of three different esomeprazole treatment strategies for long-term management of gastro-oesophageal reflux symptoms in primary care.

  Alimentary pharmacology & therapeutics 20040415

• 40 mg pantoprazole and 40 mg esomeprazole are equivalent in the healing of esophageal lesions and relief from gastroesophageal reflux disease-related symptoms.

  Journal of clinical gastroenterology 20040401

• Esomeprazole-based therapy in Helicobacter pylori eradication: a meta-analysis.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20040401

• Tenatoprazole, a novel proton pump inhibitor with a prolonged plasma half-life: effects on intragastric pH and comparison with esomeprazole in healthy volunteers.

  Alimentary pharmacology & therapeutics 20040315

• Cost-minimization analysis of treatment of gastroesophageal reflux disease. Implications of varying holding time on conclusions.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040201

• Intravenous esomeprazole.

  Drugs 20040101

• Single-isomer drugs: true therapeutic advances.

  Clinical pharmacokinetics 20040101

• Single-enantiomer drugs: elegant science, disappointing effects.

  Clinical pharmacokinetics 20040101

• Efficacy of esomeprazole in patients with acid-peptic disorders.

  Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates 20040101

• Minimal change esophagitis: prospective comparison of endoscopic and histological markers between patients with non-erosive reflux disease and normal controls using magnifying endoscopy.

  Digestive diseases (Basel, Switzerland) 20040101

• [Experience of application of Esomeprazole in patients with chronic hepatic diseases associated with acid-dependent diseases].

  Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20040101

• Esomeprazole 40 mg administered intravenously has similar safety and efficacy profiles to the oral formulation in patients with erosive esophagitis.

  Digestion 20040101

• Helicobacter pylori infection in Greenlandic patients with dyspepsia.

  International journal of circumpolar health 20040101

• Gastric acid control with esomeprazole, lansoprazole, omeprazole, pantoprazole, and rabeprazole: a five-way crossover study.

  The American journal of gastroenterology 20031201

• Esomeprazole resolves chronic heartburn in patients without erosive oesophagitis.

  Alimentary pharmacology & therapeutics 20031101

• Quality of life in relation to symptoms in patients with gastro-oesophageal reflux disease-- an analysis based on the ProGERD initiative.

  Alimentary pharmacology & therapeutics 20031015

• Esomeprazole-based one-week triple therapy with clarithromycin and metronidazole is effective in eradicating Helicobacter pylori in the absence of antimicrobial resistance.

  Alimentary pharmacology & therapeutics 20031015

• Oral esomeprazole vs. intravenous pantoprazole: a comparison of the effect on intragastric pH in healthy subjects.

  Alimentary pharmacology & therapeutics 20031001

• Esomeprazole administered through a nasogastric tube provides bioavailability similar to oral dosing.

  Alimentary pharmacology & therapeutics 20030915

• Once-daily pantoprazole 40 mg and esomeprazole 40 mg have equivalent overall efficacy in relieving GERD-related symptoms.

  Alimentary pharmacology & therapeutics 20030915

• Meta-analysis: comparative efficacy of different proton-pump inhibitors in triple therapy for Helicobacter pylori eradication.

  Alimentary pharmacology & therapeutics 20030915

• On-demand therapy for Los Angeles grade A and B reflux esophagitis: esomeprazole versus omeprazole.

  Journal of the Formosan Medical Association = Taiwan yi zhi 20030901

• Intra-oesophageal pH profiles and pharmacokinetics of pantoprazole and esomeprazole: a crossover study in patients with gastro-oesophageal reflux disease.

  European journal of gastroenterology & hepatology 20030701

• A review of the clinical and economic impact of using esomeprazole or lansoprazole for the treatment of erosive esophagitis.

  Clinical therapeutics 20030701

• Prilosec, nexium and stereoisomers.

  The Medical letter on drugs and therapeutics 20030623

• [All proton pump inhibitors are equally efficacious in standard dosages].

  Lakartidningen 20030619

• Rhabdomyolysis causing AV blockade due to possible atorvastatin, esomeprazole, and clarithromycin interaction.

  The Annals of pharmacotherapy 20030601

• One-week triple therapy with esomeprazole, clarithromycin and metronidazole provides effective eradication of Helicobacter pylori infection.

  Alimentary pharmacology & therapeutics 20030601

• Effects of 6-12 months of esomeprazole treatment on the gastric mucosa.

  The American journal of gastroenterology 20030601

• Stability of esomeprazole capsule contents after in vitro suspension in common soft foods and beverages.

  Pharmacotherapy 20030601

• [In-vitro activity of rabeprazole, lansoprazole, and esomeprazole against Helicobacter pylori].

  Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20030601

• [Impact of 24-hour intraesophageal pH monitoring with 2 channels in the diagnosis of reflux-induced otolaryngologic disorders].

  Laryngo- rhino- otologie 20030501

• [Nexium and Losec are equally good].

  Lakartidningen 20030424

• [Nexium is not better than Losec].

  Lakartidningen 20030417

• Empiric esomeprazole in the treatment of laryngopharyngeal reflux.

  The Laryngoscope 20030401

• Symptom-relieving effect of esomeprazole 40 mg daily in patients with heartburn.

  Scandinavian journal of gastroenterology 20030401

• One-week esomeprazole treatment: an effective confirmatory test in patients with suspected gastroesophageal reflux disease.

  Scandinavian journal of gastroenterology 20030401

• Synthesis or rupture: duration of acid inhibition by proton pump inhibitors.

  Drugs of today (Barcelona, Spain : 1998) 20030301

• Review article: Esomeprazole--enhanced bio-availability, specificity for the proton pump and inhibition of acid secretion.

  Alimentary pharmacology & therapeutics 20030215

• [Exaggerated interaction claims. With esomeprazole the data corroborate safety].

  MMW Fortschritte der Medizin 20030206

• Review of esomeprazole in the treatment of acid disorders.

  Expert opinion on pharmacotherapy 20030201

• Esomeprazole 20 mg and lansoprazole 15 mg in maintaining healed reflux oesophagitis: Metropole study results.

  Alimentary pharmacology & therapeutics 20030201

• Antimicrobial activity of esomeprazole versus omeprazole against Helicobacter pylori.

  The Journal of antimicrobial chemotherapy 20030201

• A proton-pump inhibitor expedition: the case histories of omeprazole and esomeprazole.

  Nature reviews. Drug discovery 20030201

• Review article: esomeprazole--the first proton pump inhibitor to be developed as an isomer.

  Alimentary pharmacology & therapeutics 20030201

• Review article: pharmacology of esomeprazole and comparisons with omeprazole.

  Alimentary pharmacology & therapeutics 20030201

• Review article: gastric acidity--comparison of esomeprazole with other proton pump inhibitors.

  Alimentary pharmacology & therapeutics 20030201

• Review article: initial therapy of reflux disease with esomeprazole.

  Alimentary pharmacology & therapeutics 20030201

• Review article: esomeprazole, 40 mg once daily, compared with lansoprazole, 30 mg once daily, in healing and symptom resolution of erosive oesophagitis.

  Alimentary pharmacology & therapeutics 20030201

• Esomeprazole 20 mg and lansoprazole 15 mg in maintaining healed reflux oesophagitis: Metropole study results.

  Alimentary pharmacology & therapeutics 20030201

• Pantoprazole: an update of its pharmacological properties and therapeutic use in the management of acid-related disorders.

  Drugs 20030101

• [Esomeprazole in treating duodenal ulcer in various modes of anti-Helicobacter therapy].

  Terapevticheskii arkhiv 20030101

• [Use of omeprazole and esomeprazole in patients suffering from bronchial asthma with associated gastroesophageal reflux disease].

  Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20030101

• An overview of proton pump inhibitors.

  Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates 20030101

• Efficacy of esomeprazole in controlling reflux symptoms, intraesophageal, and intragastric pH in patients with Barrett's esophagus.

  Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20030101

• [Experience with the application of the preparation nexium in patients by using the BioEnterics Intragastgric Balloon].

  Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20030101

• Esomeprazole 40 mg provides improved intragastric acid control as compared with lansoprazole 30 mg and rabeprazole 20 mg in healthy volunteers.

  Digestion 20030101

• [Comparative effectiveness of the antisecretory action of rabeprazole and esomeprazole in people with rapid metabolism of proton pump inhibitors].

  Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20030101

• Clinical and endoscopic evaluation of gastroesophageal reflux disease in patients successfully treated with esomeprazole.

  Arquivos de gastroenterologia 20030101

• Treatment and management of Helicobacter pylori infection.

  Current gastroenterology reports 20021201

• On-demand proton pump inhibitor therapy in patients with gastro-oesophageal reflux disease.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20021201

• Delivery of esomeprazole magnesium enteric-coated pellets through small caliber and standard nasogastric tubes and gastrostomy tubes in vitro.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20021101

• The effect of the area under the plasma concentration vs time curve and the maximum plasma concentration of esomeprazole on intragastric pH.

  European journal of clinical pharmacology 20021001

• An open non-comparative clinical study for the evaluation of safety and efficacy of esomeprazole in patients of reflux oesophagitis in Indian population.

  Journal of the Indian Medical Association 20021001

• [Pharma clinics medication of the month. Esomeprazole].

  Revue medicale de Liege 20020901

• Esomeprazole 40 mg and 20 mg is efficacious in the long-term management of patients with endoscopy-negative gastro-oesophageal reflux disease: a placebo-controlled trial of on-demand therapy for 6 months.

  European journal of gastroenterology & hepatology 20020801

• One week regimen of esomeprazole based triple therapy is sufficient for duodenal ulcer healing and Helicobacter pylori eradication in patients with duodenal ulcer disease.

  European journal of gastroenterology & hepatology 20020801

• Esomeprazole: a clinical review.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20020715

• Proton pump inhibitors: an update.

  American family physician 20020715

• Review article: esomeprazole in the treatment of Helicobacter pylori.

  Alimentary pharmacology & therapeutics 20020701

• Effects of rabeprazole, 20 mg, or esomeprazole, 20 mg, on 24-h intragastric pH and serum gastrin in healthy subjects.

  Alimentary pharmacology & therapeutics 20020701

• Pharmacologic management of gastroesophageal reflux disease.

  Current gastroenterology reports 20020601

• Views on esomeprazole-based triple therapy to treat duodenal ulcer disease and Helicobacter pylori infection.

  European journal of gastroenterology & hepatology 20020601

• Pharmacokinetic study of esomeprazole in patients with hepatic impairment.

  European journal of gastroenterology & hepatology 20020501

• Effect of esomeprazole 40 mg vs omeprazole 40 mg on 24-hour intragastric pH in patients with symptoms of gastroesophageal reflux disease.

  Digestive diseases and sciences 20020501

• Esomeprazole for acid peptic disorders.

  The Annals of pharmacotherapy 20020401

• Esomeprazole (40 mg) compared with lansoprazole (30 mg) in the treatment of erosive esophagitis.

  The American journal of gastroenterology 20020301

• Esomeprazole magnesium.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20020115

• Cost effectiveness of proton pump inhibitors in gastro-oesophageal reflux disease without oesophagitis: comparison of on-demand esomeprazole with conventional omeprazole strategies.

  PharmacoEconomics 20020101

• Cost effectiveness of esomeprazole compared with omeprazole in the acute treatment of patients with reflux oesophagitis in the UK.

  PharmacoEconomics 20020101

• Esomeprazole: a review of its use in the management of acid-related disorders in the US.

  Drugs 20020101

• [Efficacy of the one week treatment with esomeprazole (nexium), clarythromycin, and amoxycillin of duodenal ulcer associated with Helicobacter pylori].

  Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20020101

• Esomeprazole: a review of its use in the management of acid-related disorders.

  Drugs 20020101

• Gastroesophageal reflux disease: new treatments.

  Reviews in gastroenterological disorders 20020101

• Esomeprazole: update and clinical review.

  Reviews in gastroenterological disorders 20020101

• [Pharmacoeconomic aspects of the 1-week eradication treatment of duodenal ulcer associated with Helicobacter pylori].

  Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20020101

• One week of treatment with esomeprazole-based triple therapy eradicates Helicobacter pylori and heals patients with duodenal ulcer disease.

  European journal of gastroenterology & hepatology 20011201

• Systematic review of proton pump inhibitors for the acute treatment of reflux oesophagitis.

  Alimentary pharmacology & therapeutics 20011101

• Improving opportunities for effective management of gastro-oesophageal reflux disease.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20011101

• Pharmacokinetics and pharmacodynamics of esomeprazole, the S-isomer of omeprazole.

  Alimentary pharmacology & therapeutics 20011001

• Clinical pharmacology and safety profile of esomeprazole, the first enantiomerically pure proton pump inhibitor.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20011001

• Evolution of reflux disease management and the role of Nexium. Proceedings of a symposium. Porto, Portugal, 7 October 2000.

  European journal of gastroenterology & hepatology 20010901

• The new proton pump inhibitor esomeprazole is effective as a maintenance therapy in GERD patients with healed erosive oesophagitis: a 6-month, randomized, double-blind, placebo-controlled study of efficacy and safety.

  Alimentary pharmacology & therapeutics 20010701

• New-generation proton pump inhibitors: overcoming the limitations of early-generation agents.

  European journal of gastroenterology & hepatology 20010501

• Esomeprazole (nexium).

  The Medical letter on drugs and therapeutics 20010430

• Esomeprazole 20 mg maintains symptom control in endoscopy-negative gastro-oesophageal reflux disease: a controlled trial of 'on-demand' therapy for 6 months.

  Alimentary pharmacology & therapeutics 20010301

• Efficacy and safety of esomeprazole compared with omeprazole in GERD patients with erosive esophagitis: a randomized controlled trial.

  The American journal of gastroenterology 20010301

• Esomeprazole once daily for 6 months is effective therapy for maintaining healed erosive esophagitis and for controlling gastroesophageal reflux disease symptoms: a randomized, double-blind, placebo-controlled study of efficacy and safety.

  The American journal of gastroenterology 20010101

• Pharmacokinetic study of esomeprazole in the elderly.

  Clinical pharmacokinetics 20010101

• Pharmacokinetic studies with esomeprazole, the (S)-isomer of omeprazole.

  Clinical pharmacokinetics 20010101

• Safety and efficacy of long term esomeprazole therapy in patients with healed erosive oesophagitis.

  Drug safety 20010101

• Drug interaction studies with esomeprazole, the (S)-isomer of omeprazole.

  Clinical pharmacokinetics 20010101

• Relative efficacies of gastric proton-pump inhibitors on a milligram basis: desired and undesired SH reactions. Impact of chirality.

  Scandinavian journal of gastroenterology. Supplement 20010101

• Esomeprazole magnesium (Nexium).

  Reviews in gastroenterological disorders 20010101

• Esomeprazole provides improved acid control vs. omeprazole In patients with symptoms of gastro-oesophageal reflux disease.

  Alimentary pharmacology & therapeutics 20000701