16269-66-2 | 4-Chlorothieno[3,2-d]pyrimidine

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$13.00	$10.00

Description

• Catalog Number: AA84448
• Chemical Name: 4-Chlorothieno[3,2-d]pyrimidine
• CAS Number: 16269-66-2
• Molecular Formula: C6H3ClN2S
• Molecular Weight: 170.6194
• MDL Number: MFCD00122144
• SMILES: Clc1ncnc2c1scc2

Computed Properties

• Complexity: 133
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 3
• XLogP3: 1.8

Upstream Synthesis Route

4-Chlorothieno[3,2-d]pyrimidine is a versatile building block in chemical synthesis, valued for its unique structure and diverse reactivity. This compound serves as a key intermediate in the production of pharmaceuticals, agrochemicals, and materials with specialized properties. In organic synthesis, 4-Chlorothieno[3,2-d]pyrimidine can participate in diverse reactions such as substitution, condensation, and coupling processes to generate a wide array of functionalized derivatives. Its conjugated system allows for efficient incorporation into complex molecular frameworks, making it a valuable tool for designing novel compounds with targeted properties. Due to its strong electron-withdrawing chlorine group and aromatic thieno-pyrimidine core, this compound can facilitate the synthesis of bioactive molecules, advanced materials, and functionalized building blocks for further elaboration. Its broad utility in synthetic chemistry highlights its importance as a fundamental scaffold for creating valuable compounds across various industries.

Literature

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101