163222-33-1 | Ezetimibe

Packsize	Purity	Availability	Price	Discounted Price
10mg	98%	in stock	$6.00	$4.00
50mg	99%	in stock	$6.00	$4.00
100mg	98%	in stock	$9.00	$6.00
250mg	98%	in stock	$12.00	$9.00
1g	99%	in stock	$25.00	$17.00
5g	99%	in stock	$106.00	$74.00
10g	98%	in stock	$194.00	$136.00
25g	98%	in stock	$409.00	$287.00
100g	98%	in stock	$1,369.00	$958.00

Description

• Catalog Number: AA85208
• Chemical Name: Ezetimibe
• CAS Number: 163222-33-1
• Molecular Formula: C24H21F2NO3
• Molecular Weight: 409.4252
• MDL Number: MFCD30189368
• SMILES: Oc1ccc(cc1)[C@@H]1[C@@H](CC[C@@H](c2ccc(cc2)F)O)C(=O)N1c1ccc(cc1)F

Computed Properties

• Complexity: 567
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 3
• Heavy Atom Count: 30
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 6
• XLogP3: 4

Literature

• Bean peptides have higher in silico binding affinities than ezetimibe for the N-terminal domain of cholesterol receptor Niemann-Pick C1 Like-1.

  Peptides 20170401

• Bisphenol A promotes cholesterol absorption in Caco-2 cells by up-regulation of NPC1L1 expression.

  Lipids in health and disease 20170101

• Utilization of human nuclear receptors as an early counter screen for off-target activity: a case study with a compendium of 615 known drugs.

  Toxicological sciences : an official journal of the Society of Toxicology 20150601

• Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11).

  Toxicological sciences : an official journal of the Society of Toxicology 20131201

• Structure-activity relationship for FDA approved drugs as inhibitors of the human sodium taurocholate cotransporting polypeptide (NTCP).

  Molecular pharmaceutics 20130304

• Effects of simvastatin, atorvastatin, ezetimibe, and ezetimibe + simvastatin combination on the inflammatory process and on the liver metabolic changes of arthritic rats.

  Fundamental & clinical pharmacology 20121201

• Optimized self nano-emulsifying systems of ezetimibe with enhanced bioavailability potential using long chain and medium chain triglycerides.

  Colloids and surfaces. B, Biointerfaces 20121201

• Modulation of lipid metabolism with the overexpression of NPC1L1 in mouse liver.

  Journal of lipid research 20121101

• Inhibition of intestinal cholesterol absorption decreases atherosclerosis but not adipose tissue inflammation.

  Journal of lipid research 20121101

• Statin myopathy: a lipid clinic experience on the tolerability of statin rechallenge.

  Cardiovascular therapeutics 20121001

• Oxidative stress improvement is associated with increased levels of taurine in CKD patients undergoing lipid-lowering therapy.

  Amino acids 20121001

• Dysfunctional HDL: a novel important diagnostic and therapeutic target in cardiovascular disease?

  Progress in lipid research 20121001

• Ezetimibe inhibits lymphatic transport of esterified cholesterol but not free cholesterol in thoracic lymph duct-cannulated rats.

  Cardiovascular drugs and therapy 20121001

• Differences in synthesis and absorption of cholesterol of two effective lipid-lowering therapies.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20121001

• Ezetimibe blocks the internalization of NPC1L1 and cholesterol in mouse small intestine.

  Journal of lipid research 20121001

• Long-term effects of ezetimibe-plus-statin therapy on low-density lipoprotein cholesterol levels as compared with double-dose statin therapy in patients with coronary artery disease.

  Atherosclerosis 20121001

• Clinical benefits of ezetimibe use: is absence of proof, proof of absence?

  Expert opinion on pharmacotherapy 20121001

• [Lipid therapy in daily routine].

  Deutsche medizinische Wochenschrift (1946) 20121001

• Dyslipidemia: management using optimal lipid-lowering therapy.

  The Annals of pharmacotherapy 20121001

• Entry of hepatitis C virus into the cell: a therapeutic target.

  World journal of gastroenterology 20120907

• Managing the underestimated risk of statin-associated myopathy.

  International journal of cardiology 20120906

• Lipid-lowering therapy in chronic kidney disease: is there a role for ezetimibe?

  Journal of renal care 20120901

• Discovery, synthesis and evaluation of novel cholesterol absorption inhibitors.

  Chemical biology & drug design 20120901

• Effects of lipid-lowering treatment on platelet reactivity and platelet-leukocyte aggregation in diabetic patients without and with chronic kidney disease: a randomized trial.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120901

• The safety and effectiveness of statins as treatment for HIV-dyslipidemia: the evidence so far and the future challenges.

  Expert opinion on pharmacotherapy 20120901

• Hepatitis C RNA clearance after treatment with ezetimibe.

  Liver international : official journal of the International Association for the Study of the Liver 20120901

• Lipid-lowering therapy in persons with chronic kidney disease: a systematic review and meta-analysis.

  Annals of internal medicine 20120821

• Lipid-altering efficacy of ezetimibe plus statin and statin monotherapy and identification of factors associated with treatment response: a pooled analysis of over 21,000 subjects from 27 clinical trials.

  Atherosclerosis 20120801

• Statin-induced immunomodulation alters peripheral invariant natural killer T-cell prevalence in hyperlipidemic patients.

  Cardiovascular drugs and therapy 20120801

• Comparison of the efficacy and safety of statin and statin/ezetimibe therapy after coronary stent implantation in patients with stable angina.

  Journal of cardiology 20120801

• Ezetimibe: A biomarker for efficacy of liver directed UGT1A1 gene therapy for inherited hyperbilirubinemia.

  Biochimica et biophysica acta 20120801

• Relative efficacy of antilipemic agents in non–high-density lipoprotein cholesterol reduction.

  Journal of pharmacy practice 20120801

• A novel method for the determination of the site of glucuronidation by ion mobility spectrometry-mass spectrometry.

  Drug metabolism and disposition: the biological fate of chemicals 20120801

• Nonalcoholic fatty liver disease and lipids.

  Current opinion in lipidology 20120801

• Pleiotropic effects of ezetimibe/simvastatin vs. high dose simvastatin.

  International journal of cardiology 20120726

• Inhibition of PCSK9 in familial hypercholesterolaemia.

  Lancet (London, England) 20120707

• Effect of a monoclonal antibody to PCSK9, REGN727/SAR236553, to reduce low-density lipoprotein cholesterol in patients with heterozygous familial hypercholesterolaemia on stable statin dose with or without ezetimibe therapy: a phase 2 randomised controlled trial.

  Lancet (London, England) 20120707

• [Use of ezetimibe in the treatment of familial hypercholesterolemia in children and adolescents].

  Anales de pediatria (Barcelona, Spain : 2003) 20120701

• Comparative efficacy and safety of fenofibrate/pravastatin plus ezetimibe triple therapy and simvastatin/ezetimibe dual therapy in type 2 diabetic patients with mixed hyperlipidaemia and cardiovascular disease.

  Diabetes & vascular disease research 20120701

• A review of the role of apolipoprotein C-II in lipoprotein metabolism and cardiovascular disease.

  Metabolism: clinical and experimental 20120701

• A comparison of the efficacy of combined ezetimibe and statin therapy with doubling of statin dose in patients with remnant lipoproteinemia on previous statin therapy.

  Journal of cardiology 20120701

• Niemann-Pick C1-Like 1 and cholesterol uptake.

  Biochimica et biophysica acta 20120701

• Blockade of cholesterol absorption by ezetimibe reveals a complex homeostatic network in enterocytes.

  Journal of lipid research 20120701

• Comparison of the intestinal absorption and bioavailability of γ-tocotrienol and α-tocopherol: in vitro, in situ and in vivo studies.

  Biopharmaceutics & drug disposition 20120701

• Compartment-specific gene regulation of the CAR inducer efavirenz in vivo.

  Clinical pharmacology and therapeutics 20120701

• Identical LDL-cholesterol lowering but non-identical effects on NF-κB activity: High dose simvastatin vs combination therapy with ezetimibe.

  Atherosclerosis 20120701

• Hypertension in aortic stenosis: implications for left ventricular structure and cardiovascular events.

  Hypertension (Dallas, Tex. : 1979) 20120701

• Recent clinical studies of the effects of lipid-modifying therapies.

  The American journal of cardiology 20120701

• The ezetimibe controversy - can this be resolved by comparing the clinical trials with simvastatin and ezetimibe alone and together?

  Expert opinion on pharmacotherapy 20120701

• The effect of ezetimibe and simvastatin on hemostasis in patients with isolated hypercholesterolemia.

  Fundamental & clinical pharmacology 20120601

• Cost-effectiveness of extended-release niacin/laropiprant added to a stable simvastatin dose in secondary prevention patients not at cholesterol goal in Germany.

  The European journal of health economics : HEPAC : health economics in prevention and care 20120601

• Warnings without guidance: patient responses to an FDA warning about ezetimibe.

  Medical care 20120601

• A review of time courses and predictors of lipid changes with fenofibric acid-statin combination.

  Cardiovascular drugs and therapy 20120601

• Ezetimibe reduces fatty acid quantity in liver and decreased inflammatory cell infiltration and improved NASH in medaka model.

  Biochemical and biophysical research communications 20120525

• Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.

  Journal of medicinal chemistry 20120524

• Peripheral arterial disease of the lower extremities.

  Archives of medical science : AMS 20120509

• Ezetimibe ameliorates intestinal chylomicron overproduction and improves glucose tolerance in a diet-induced hamster model of insulin resistance.

  American journal of physiology. Gastrointestinal and liver physiology 20120501

• Simvastatin interactions with other drugs.

  Expert opinion on drug safety 20120501

• Cardiovascular primary prevention: how high should we set the bar?

  Archives of internal medicine 20120423

• New fibrate use and acute renal outcomes in elderly adults: a population-based study.

  Annals of internal medicine 20120417

• Augmented cholesterol absorption and sarcolemmal sterol enrichment slow small intestinal transit in mice, contributing to cholesterol cholelithogenesis.

  The Journal of physiology 20120415

• Therapy of gallstone disease: What it was, what it is, what it will be.

  World journal of gastrointestinal pharmacology and therapeutics 20120406

• The SHARP trial: lessons learnt; answers and more questions!

  International journal of cardiology 20120405

• Lipid-altering efficacy of ezetimibe/simvastatin 10/20 mg compared to rosuvastatin 10 mg in high-risk patients with and without type 2 diabetes mellitus inadequately controlled despite prior statin monotherapy.

  Cardiovascular therapeutics 20120401

• Ezetimibe and regression of carotid atherosclerosis: importance of measuring plaque burden.

  Stroke 20120401

• A randomized, double-blind, placebo-controlled study of the safety and tolerance of regadenoson in subjects with stage 3 or 4 chronic kidney disease.

  Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 20120401

• Approach to lipid therapy in the patient with atherosclerotic vascular disease.

  Current treatment options in cardiovascular medicine 20120401

• Characterization of in vitro glucuronidation clearance of a range of drugs in human kidney microsomes: comparison with liver and intestinal glucuronidation and impact of albumin.

  Drug metabolism and disposition: the biological fate of chemicals 20120401

• Non-systemic drugs: a critical review.

  Current pharmaceutical design 20120401

• Novel LDL-oriented pharmacotherapeutical strategies.

  Pharmacological research 20120401

• Effect of extended-release niacin on new-onset diabetes among hyperlipidemic patients treated with ezetimibe/simvastatin in a randomized controlled trial.

  Diabetes care 20120401

• Effect of lipid lowering on new-onset atrial fibrillation in patients with asymptomatic aortic stenosis: the Simvastatin and Ezetimibe in Aortic Stenosis (SEAS) study.

  American heart journal 20120401

• NASH is an Inflammatory Disorder: Pathogenic, Prognostic and Therapeutic Implications.

  Gut and liver 20120401

• Impact of QRS duration and morphology on the risk of sudden cardiac death in asymptomatic patients with aortic stenosis: the SEAS (Simvastatin and Ezetimibe in Aortic Stenosis) Study.

  Journal of the American College of Cardiology 20120327

• Letter by Weingartner et al regarding article, 'Combined effects of ezetimibe and phytosterols on cholesterol metabolism: a randomized, controlled feeding study in humans'.

  Circulation 20120313

• Effect of atorvastatin monotherapy and low-dose atorvastatin/ezetimibe combination on fasting and postprandial triglycerides in combined hyperlipedemia.

  Journal of cardiovascular pharmacology and therapeutics 20120301

• Ezetimibe alone or in combination with pitavastatin prevents kidney dysfunction in 5/6 nephrectomized rats fed high-cholesterol.

  Metabolism: clinical and experimental 20120301

• Identification of drugs and drug metabolites as substrates of multidrug resistance protein 2 (MRP2) using triple-transfected MDCK-OATP1B1-UGT1A1-MRP2 cells.

  British journal of pharmacology 20120301

• Molecular mechanism of altered ezetimibe disposition in nonalcoholic steatohepatitis.

  Drug metabolism and disposition: the biological fate of chemicals 20120301

• A risk score for predicting mortality in patients with asymptomatic mild to moderate aortic stenosis.

  Heart (British Cardiac Society) 20120301

• Use of ordered mesoporous silica to enhance the oral bioavailability of ezetimibe in dogs.

  Journal of pharmaceutical sciences 20120301

• Impact of efavirenz on intestinal metabolism and transport: insights from an interaction study with ezetimibe in healthy volunteers.

  Clinical pharmacology and therapeutics 20120301

• The need for a benchmark of the practice of cardiology.

  Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20120301

• [Genetic principles of food related problems--familial hypercholesterolaemia].

  Journal de pharmacie de Belgique 20120301

• Effects of 4-week administration of simvastatin in different doses on heart rate and blood pressure after metoprolol injection in normocholesterolaemic and normotensive rats.

  Archives of medical science : AMS 20120227

• Reduction in atherosclerotic events: a retrospective study in an outpatient cardiology practice.

  Archives of medical science : AMS 20120227

• Management of familial hypercholesterolaemia in children and adolescents.

  Journal of paediatrics and child health 20120201

• A review of the rationale for additional therapeutic interventions to attain lower LDL-C when statin therapy is not enough.

  Current atherosclerosis reports 20120201

• Efficacy and safety of coadministration of rosuvastatin, ezetimibe, and colestimide in heterozygous familial hypercholesterolemia.

  The American journal of cardiology 20120201

• Inappropriately high left-ventricular mass in asymptomatic mild-moderate aortic stenosis.

  Journal of hypertension 20120201

• Ezetimibe/simvastatin: a guide to its clinical use in hypercholesterolemia.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20120201

• Identification of the Niemann-Pick C1-like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor.

  Nature medicine 20120201

• Imperative to consider multiple initiatives to maximize prescribing efficiency from generic availability: case history from Abu Dhabi.

  Expert review of pharmacoeconomics & outcomes research 20120201

• [Elevated augmentation index].

  Deutsche medizinische Wochenschrift (1946) 20120201

• Severe neutropenia in a renal transplant patient suggesting an interaction between mycophenolate and fenofibrate.

  Current drug safety 20120201

• Structure of the major degradant of ezetimibe.

  Journal of pharmaceutical and biomedical analysis 20120125

• Clinical implications of electrocardiographic left ventricular strain and hypertrophy in asymptomatic patients with aortic stenosis: the Simvastatin and Ezetimibe in Aortic Stenosis study.

  Circulation 20120117

• [Nephrology].

  Revue medicale suisse 20120111

• In brief: Ezetimibe/simvastatin (Vytorin) in chronic kidney disease.

  The Medical letter on drugs and therapeutics 20120109

• One-year cholesterol lowering treatment reduces medial temporal lobe atrophy and memory decline in stroke-free elderly with atrial fibrillation: evidence from a parallel group randomized trial.

  International journal of geriatric psychiatry 20120101

• The effect of ezetimibe, administered alone or in combination with simvastatin, on lymphocyte cytokine release in patients with elevated cholesterol levels.

  Journal of internal medicine 20120101

• Micelle-enhanced spectrofluorimetric method for determination of cholesterol-reducing drug ezetimibe in dosage forms.

  Journal of fluorescence 20120101

• Hypertriglyceridemia, Metabolic Syndrome, and Cardiovascular Disease in HIV-Infected Patients: Effects of Antiretroviral Therapy and Adipose Tissue Distribution.

  International journal of vascular medicine 20120101

• Quantitative prediction of intestinal glucuronidation of drugs in rats using in vitro metabolic clearance data.

  Drug metabolism and pharmacokinetics 20120101

• The chylomicron: relationship to atherosclerosis.

  International journal of vascular medicine 20120101

• Effect of ezetimibe on remnant-like particle cholesterol in subjects with metabolic syndrome.

  Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20120101

• Virtual histology evaluation of atherosclerosis regression during atorvastatin and ezetimibe administration: HEAVEN study.

  Circulation journal : official journal of the Japanese Circulation Society 20120101

• Drug-induced immune thrombocytopenia: a descriptive survey in the French PharmacoVigilance database.

  Platelets 20120101

• Atorvastatin 10 mg plus ezetimibe 10mg compared with atorvastatin 20 mg: impact on the lipid profile in Japanese patients with abnormal glucose tolerance and coronary artery disease.

  Journal of cardiology 20120101

• Ezetimibe alone and in combination lowers the concentration of small, dense low-density lipoproteins in type 2 diabetes mellitus.

  Atherosclerosis 20120101

• Low-density lipoprotein cholesterol lowering therapy and established atherosclerosis.

  Circulation journal : official journal of the Japanese Circulation Society 20120101

• Ezetimibe: its novel effects on the prevention and the treatment of cholesterol gallstones and nonalcoholic Fatty liver disease.

  Journal of lipids 20120101

• Molecular Mechanisms Underlying the Link between Nuclear Receptor Function and Cholesterol Gallstone Formation.

  Journal of lipids 20120101

• Is combination therapy an effective way of reaching lipid goals in type 2 diabetes mellitus?

  Expert review of clinical pharmacology 20120101

• Cholesterol synthesis is associated with hepatic lipid content and dependent on fructose/glucose intake in healthy humans.

  Experimental diabetes research 20120101

• Genetic interactions between chromosomes 11 and 18 contribute to airway hyperresponsiveness in mice.

  PloS one 20120101

• Lipid disorders in elderly hypertensive patients.

  International journal of hypertension 20120101

• Regression of left ventricular mass following conversion from conventional hemodialysis to thrice weekly in-centre nocturnal hemodialysis.

  BMC nephrology 20120101

• Metabolic syndrome in the Mediterranean region: Current status.

  Indian journal of endocrinology and metabolism 20120101

• Impact of circulating cholesterol levels on growth and intratumoral androgen concentration of prostate tumors.

  PloS one 20120101

• Ezetimibe/simvastatin 10/40 mg versus atorvastatin 40 mg in high cardiovascular risk patients with primary hypercholesterolemia: a randomized, double-blind, active-controlled, multicenter study.

  Lipids in health and disease 20120101

• Changes in Lipids and Lipoproteins after Selective LDL Apheresis (7-Year Experience).

  Cholesterol 20120101

• Involvement of a periodontal pathogen, Porphyromonas gingivalis on the pathogenesis of non-alcoholic fatty liver disease.

  BMC gastroenterology 20120101

• Multiple functions of microsomal triglyceride transfer protein.

  Nutrition & metabolism 20120101

• Ezetimibe ameliorates atherosclerotic and inflammatory markers, atherogenic lipid profiles, insulin sensitivity, and liver dysfunction in Japanese patients with hypercholesterolemia.

  Journal of atherosclerosis and thrombosis 20120101

• The effects of apolipoprotein F deficiency on high density lipoprotein cholesterol metabolism in mice.

  PloS one 20120101

• Changes in prescription patterns before and after reporting of the Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression trial (ENHANCE) results and expected effects on low-density lipoprotein-cholesterol reduction.

  Journal of clinical lipidology 20120101

• C57Bl/6 N mice on a western diet display reduced intestinal and hepatic cholesterol levels despite a plasma hypercholesterolemia.

  BMC genomics 20120101

• Adoption of new drugs by physicians: a survival analysis.

  BMC health services research 20120101

• Attenuation of niacin-induced prostaglandin D(2) generation by omega-3 fatty acids in THP-1 macrophages and Langerhans dendritic cells.

  Journal of inflammation research 20120101

• Rosuvastatin: a review of the pharmacology and clinical effectiveness in cardiovascular disease.

  Clinical Medicine Insights. Cardiology 20120101

• [Statin-ezetimibe combination in hyperlipidemia treatment].

  Casopis lekaru ceskych 20120101

• Regulation of reverse cholesterol transport - a comprehensive appraisal of available animal studies.

  Nutrition & metabolism 20120101

• Achieving secondary prevention low-density lipoprotein particle concentration goals using lipoprotein cholesterol-based data.

  PloS one 20120101

• Ezetimibe ameliorates early diabetic nephropathy in db/db mice.

  Journal of atherosclerosis and thrombosis 20120101

• Efficacy of short-term high-dose statin in preventing contrast-induced nephropathy: a meta-analysis of seven randomized controlled trials.

  PloS one 20120101

• A comparative effect of atorvastatin with other statins in patients of hyperlipidemia.

  Indian journal of pharmacology 20120101

• Paraoxonase activity and expression is modulated by therapeutics in experimental rat nonalcoholic Fatty liver disease.

  International journal of hepatology 20120101

• Anti-inflammatory effect of simvastatin in an experimental model of spinal cord trauma: involvement of PPAR-α.

  Journal of neuroinflammation 20120101

• Effect of a New Prokinetic Agent DA-9701 Formulated with Corydalis Tuber and Pharbitidis Semen on Cytochrome P450 and UDP-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes.

  Evidence-based complementary and alternative medicine : eCAM 20120101

• Nutrition and nonalcoholic Fatty liver disease: the significance of cholesterol.

  International journal of hepatology 20120101

• Treatment patterns and risk factor control in patients with and without metabolic syndrome in cardiac rehabilitation.

  Vascular health and risk management 20120101

• Improvement of the bioavailability and glycaemic metabolism of cinnamon oil in rats by liquid loadable tablets.

  TheScientificWorldJournal 20120101

• Different stability-indicating chromatographic techniques for the determination of netobimin.

  Journal of analytical methods in chemistry 20120101

• A tool for evaluating the potential for cost-effective outcomes measurement.

  International journal of general medicine 20120101

• A pleiotropic role for the orphan nuclear receptor small heterodimer partner in lipid homeostasis and metabolic pathways.

  Journal of lipids 20120101

• Involvement of cholesterol membrane transporter Niemann-Pick C1-like 1 in the intestinal absorption of lutein.

  Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20120101

• Interactions between Bile Acids and Nuclear Receptors and Their Effects on Lipid Metabolism and Liver Diseases.

  Journal of lipids 20120101

• Use of once-weekly statin in combination with ezetimibe in a patient with mitochondrial disease.

  BMJ case reports 20120101

• Stress studies of tenofovir disoproxil fumarate by HPTLC in bulk drug and pharmaceutical formulation.

  TheScientificWorldJournal 20120101

• Regular exercise or changing diet does not influence aortic valve disease progression in LDLR deficient mice.

  PloS one 20120101

• Effect of ursodeoxycholic Acid alone and ursodeoxycholic Acid plus domperidone on radiolucent gallstones and gallbladder contractility in humans.

  Gastroenterology research and practice 20120101

• Lipid-regulating effect of traditional chinese medicine: mechanisms of actions.

  Evidence-based complementary and alternative medicine : eCAM 20120101

• Ezetimibe reduces urinary albumin excretion in hypercholesterolaemic type 2 diabetes patients with microalbuminuria.

  The Journal of international medical research 20120101

• Efficacy, safety and tolerability of ongoing statin plus ezetimibe versus doubling the ongoing statin dose in hypercholesterolemic Taiwanese patients: an open-label, randomized clinical trial.

  BMC research notes 20120101

• Reviewing the medical literature: five notable articles in general internal medicine from 2010 and 2011.

  Open medicine : a peer-reviewed, independent, open-access journal 20120101

• Ezetimibe improves endothelial function and inhibits Rho-kinase activity associated with inhibition of cholesterol absorption in humans.

  Circulation journal : official journal of the Japanese Circulation Society 20120101

• Targeted In Situ Gene Correction of Dysfunctional APOE Alleles to Produce Atheroprotective Plasma ApoE3 Protein.

  Cardiology research and practice 20120101

• Simultaneous determination of atorvastatin calcium, ezetimibe, and fenofibrate in a tablet formulation by HPLC.

  Journal of AOAC International 20120101

• Xanthine oxidase and uric Acid in atrial fibrillation.

  Frontiers in physiology 20120101

• Double-dose pravastatin versus add-on ezetimibe with low-dose pravastatin - effects on LDL cholesterol, cholesterol absorption, and cholesterol synthesis in Japanese patients with hypercholesterolemia (PEAS study).

  Journal of atherosclerosis and thrombosis 20120101

• Antiretroviral simplification with darunavir/ritonavir monotherapy in routine clinical practice: safety, effectiveness, and impact on lipid profile.

  PloS one 20120101

• Autosomal recessive hypercholesterolaemia in a Morrocan family due to a mutation of the G266C LDL receptor.

  BMJ case reports 20120101

• [The influence of ezetimibe and simvaststin on platelet aggregation and protein c system in patients with coronary heart disease and hypercholesterolemia].

  Klinicheskaia meditsina 20120101

• Ezetimibe and simvastatin reduce cholesterol levels in zebrafish larvae fed a high-cholesterol diet.

  Cholesterol 20120101

• Mipomersen: evidence-based review of its potential in the treatment of homozygous and severe heterozygous familial hypercholesterolemia.

  Core evidence 20120101

• Efficacy of ezetimibe is associated with gender and baseline lipid levels in patients with type 2 diabetes.

  Journal of atherosclerosis and thrombosis 20120101

• Evidence for cholesterol hyperabsorbers and hyperproducers based on comparative low-density lipoprotein reductions achieved by ezetimibe versus statins.

  Journal of cardiopulmonary rehabilitation and prevention 20120101

• How to use ezetimibe as an anti-atherogenic agent via inhibition of Rho-kinase.

  Circulation journal : official journal of the Japanese Circulation Society 20120101

• Apheresis in homozygous familial hypercholesterolemia: the results of a follow-up of all Norwegian patients with homozygous familial hypercholesterolemia.

  Journal of clinical lipidology 20120101

• Lipoprotein(a) particle concentration and lipoprotein(a) cholesterol assays yield discordant classification of patients into four physiologically discrete groups.

  Journal of clinical lipidology 20120101

• Use of Lipid-Lowering Medications and the Likelihood of Achieving Optimal LDL-Cholesterol Goals in Coronary Artery Disease Patients.

  Cholesterol 20120101

• Ezetimibe therapy: mechanism of action and clinical update.

  Vascular health and risk management 20120101

• Nutraceutical pill containing berberine versus ezetimibe on plasma lipid pattern in hypercholesterolemic subjects and its additive effect in patients with familial hypercholesterolemia on stable cholesterol-lowering treatment.

  Lipids in health and disease 20120101

• Ezetimibe - a new approach in hypercholesterolemia management.

  Pharmacological reports : PR 20120101

• Effect of ezetimibe on insulin secretion in db/db diabetic mice.

  Experimental diabetes research 20120101

• Quantitative Longitudinal Imaging of Vascular Inflammation and Treatment by Ezetimibe in apoE Mice by FMT Using New Optical Imaging Biomarkers of Cathepsin Activity and α(v)β(3) Integrin.

  International journal of molecular imaging 20120101

• IMproving the imPlemEntation of cuRrent guidelines for the mAnagement of major coronary hearT disease rIsk factors by multifactorial interVEntion. The IMPERATIVE renal analysis.

  Archives of medical science : AMS 20111231

• Lipids, blood pressure, kidney - what was new in 2011?

  Archives of medical science : AMS 20111231

• Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy.

  The New England journal of medicine 20111215

• PTU induction provide quick screening of hypo and hyperlipidemia.

  Pakistan journal of biological sciences : PJBS 20111215

• Influence of age, gender, and race on the efficacy of adding ezetimibe to atorvastatin vs. atorvastatin up-titration in patients at moderately high or high risk for coronary heart disease.

  International journal of cardiology 20111201

• High-density lipoprotein cholesterol as a predictor of clinical outcomes in patients achieving low-density lipoprotein cholesterol targets with statins after percutaneous coronary intervention.

  Heart (British Cardiac Society) 20111201

• Familial hypercholesterolemia: present and future management.

  Current cardiology reports 20111201

• Therapeutic effects of ezetimibe for non-alcoholic steatohepatitis in fatty liver shionogi-ob/ob mice.

  Hepatology research : the official journal of the Japan Society of Hepatology 20111201

• Effect of dalcetrapib, a CETP modulator, on non-cholesterol sterol markers of cholesterol homeostasis in healthy subjects.

  Atherosclerosis 20111201

• Cholesterol-lowering therapy for the treatment of nonalcoholic fatty liver disease: an update.

  Current opinion in lipidology 20111201

• Impact of ezetimibe coadministered with statins on cardiovascular events following acute coronary syndrome: a 3-year population-based retrospective cohort study in taiwan.

  Clinical therapeutics 20111201

• Lipid lowering in patients with chronic kidney disease: a SHARP turn in the wrong direction?

  European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20111201

• [Effects of different statins, ezetimibe/simvastatin combination on hsCRP levels in unstable angina pectoris and non-ST elevation myocardial infarction patients: a randomized trial].

  Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20111201

• Intestinal sterol transporters and cholesterol absorption inhibition.

  Current opinion in lipidology 20111201

• Medical reversal: why we must raise the bar before adopting new technologies.

  The Yale journal of biology and medicine 20111201

• Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

  PLoS computational biology 20111201

• Very Late Stent Thrombosis due to Neointimal Rupture After Paclitaxel-Eluting Stent Implantation.

  Korean circulation journal 20111201

• [Achievement of therapeutic target in subjects on statin treatment in clinical practice. Results of the STAR (Statins Target Assessment in Real practice) study].

  Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 20111201

• ACP Journal Club. Simvastatin plus ezetimibe reduced major atherosclerotic events in patients with chronic kidney disease.

  Annals of internal medicine 20111115

• Persistent lipid abnormalities in statin-treated patients with diabetes mellitus in Europe and Canada: results of the Dyslipidaemia International Study.

  Diabetic medicine : a journal of the British Diabetic Association 20111101

• ApoB siRNA-induced liver steatosis is resistant to clearance by the loss of fatty acid transport protein 5 (Fatp5).

  Lipids 20111101

• National differences in screening programmes for cardiovascular risks could obstruct understanding of cardiovascular prevention studies in Europe.

  Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20111101

• Comparison of the effects of simvastatin vs. rosuvastatin vs. simvastatin/ezetimibe on parameters of insulin resistance.

  International journal of clinical practice 20111101

• Lipid lowering drugs and gallstones: a therapeutic option?

  Current pharmaceutical design 20111101

• Cholesterol conundrum.

  Scientific American 20111101

• Predictors of echocardiographic progression in patients with mild aortic stenosis.

  Korean circulation journal 20111101

• Role of ezetimibe in non-alcoholic fatty liver disease.

  World journal of hepatology 20111027

• Nitroxide derivatives for imaging of hypercholesterolemia-induced kidney dysfunction and assessing the effectiveness of antilipidemic drugs.

  Molecular pharmaceutics 20111003

• Cardiovascular medications and risk of cancer.

  The American journal of cardiology 20111001

• [Magnitude and characteristics of residual lipid risk in patients with a history of coronary revascularization: the ICP-bypass study].

  Revista espanola de cardiologia 20111001

• Left atrial systolic force in asymptomatic aortic stenosis.

  Echocardiography (Mount Kisco, N.Y.) 20111001

• Lipid-altering efficacy of switching to ezetimibe/simvastatin 10/20 mg versus rosuvastatin 10 mg in high-risk patients with and without metabolic syndrome.

  Diabetes & vascular disease research 20111001

• The role of ezetimibe in LDL cholesterol goal attainment in very high risk patients: the rosuvastatin monotherapy looks to be insufficient.

  Current medical research and opinion 20111001

• Smaller Mean LDL Particle Size and Higher Proportion of Small Dense LDL in Korean Type 2 Diabetic Patients.

  Diabetes & metabolism journal 20111001

• Are patients undergoing treatment of hyperlipidaemia with statins the best candidates for early cardiac rehabilitation?

  Archives of medical science : AMS 20111001

• An attempt to make lipid-lowering therapy more effective in Hungary. The results of MULTI GAP 2010 and the PLUS Program.

  Archives of medical science : AMS 20111001

• Effectiveness and tolerability of ezetimibe co-administered with statins versus statin dose-doubling in high-risk patients with persistent hyperlipidemia: The EZE(STAT)2 trial.

  Archives of medical science : AMS 20111001

• The effect of ezetimibe on peripheral arterial atherosclerosis depends upon statin use at baseline.

  Atherosclerosis 20110901

• Ezetimibe restores biliary cholesterol excretion in mice expressing Niemann-Pick C1-Like 1 only in liver.

  Biochimica et biophysica acta 20110901

• Another clinical evidence straw on the $4 billion ezetimibe camel's back.

  Atherosclerosis 20110901

• Plaque rupture and thrombosis are reduced by lowering cholesterol levels and crystallization with ezetimibe and are correlated with fluorodeoxyglucose positron emission tomography.

  Arteriosclerosis, thrombosis, and vascular biology 20110901

• Combination therapy for dyslipidemia.

  Current opinion in cardiology 20110901

• Impact of ezetimibe coadministered with statins on cardiovascular events following acute coronary syndrome: a 3-year population-based retrospective cohort study in Taiwan.

  Clinical therapeutics 20110901

• Comparison of clinical outcomes of hydrophilic and lipophilic statins in patients with acute myocardial infarction.

  The Korean journal of internal medicine 20110901

• Low-density lipoprotein lowering does not improve calf muscle perfusion, energetics, or exercise performance in peripheral arterial disease.

  Journal of the American College of Cardiology 20110830

• Learning to walk before we run: the mechanics of medical intervention for peripheral arterial disease.

  Journal of the American College of Cardiology 20110830

• A formal synthesis of ezetimibe via cycloaddition/rearrangement cascade reaction.

  The Journal of organic chemistry 20110819

• Safety and efficacy of ezetimibe added on to rosuvastatin 5 or 10 mg versus up-titration of rosuvastatin in patients with hypercholesterolemia (the ACTE Study).

  The American journal of cardiology 20110815

• Differences in cardiovascular risk profile between electrocardiographic hypertrophy versus strain in asymptomatic patients with aortic stenosis (from SEAS data).

  The American journal of cardiology 20110815

• Do functional foods have a role in the prevention of cardiovascular disease?

  Circulation 20110802

• Combined effects of ezetimibe and phytosterols on cholesterol metabolism: a randomized, controlled feeding study in humans.

  Circulation 20110802

• Impact of hypertriglyceridemia on endothelial dysfunction during statin ± ezetimibe therapy in patients with coronary heart disease.

  The American journal of cardiology 20110801

• Ezetimibe combined with simvastatin compared with simvastatin alone results in a greater suppression of oxidative stress and enhanced fibrinolysis in patients after acute coronary events.

  Journal of cardiovascular pharmacology 20110801

• Ezetimibe improves postprandial hyperlipemia and its induced endothelial dysfunction.

  Atherosclerosis 20110801

• The ezetimibe controversy: implications for clinical practice.

  Therapeutic advances in cardiovascular disease 20110801

• Begin with the real-world patients of non-goal-achieved hypercholesterolemia in taiwan through the ezetimibe/simvastatin tablet - The BRAVO Study.

  Current medical research and opinion 20110801

• Where does the interplay between cholesterol absorption and synthesis in the context of statin and/or ezetimibe treatment stand today?

  Atherosclerosis 20110801

• Opening a new lipid 'apo-thecary': incorporating apolipoproteins as potential risk factors and treatment targets to reduce cardiovascular risk.

  Mayo Clinic proceedings 20110801

• [The efficacy of ezetimibe on nonalcoholic fatty liver disease (NAFLD)].

  Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20110801

• Why, when and how should hypertriglyceridemia be treated in the high-risk cardiovascular patient?

  Expert review of cardiovascular therapy 20110801

• Retrospective study on antihyperlipidemic efficacy and safety of simvastatin, ezetimibe and their combination in Korean adults.

  Archives of pharmacal research 20110801

• Trial clouds use of niacin with a statin.

  Harvard heart letter : from Harvard Medical School 20110801

• Managing dyslipidaemia: evolving role of combination therapy.

  Journal of the Indian Medical Association 20110801

• What is the degradation product of ezetimibe?

  Journal of pharmaceutical and biomedical analysis 20110715

• Effect of lipid-lowering treatment on natural history of heterozygous familial hypercholesterolemia in past three decades.

  The American journal of cardiology 20110715

• Lipid-altering efficacy and safety profile of combination therapy with ezetimibe/statin vs. statin monotherapy in patients with and without diabetes: an analysis of pooled data from 27 clinical trials.

  Diabetes, obesity & metabolism 20110701

• Ambient air pollution and lipoprotein-associated phospholipase A₂ in survivors of myocardial infarction.

  Environmental health perspectives 20110701

• Statin myopathy: significant problem with minimal awareness by clinicians and no emphasis by clinical investigators.

  Angiology 20110701

• Ezetimibe beneficially influences fasting and postprandial triglyceride-rich lipoproteins in type 2 diabetes.

  Atherosclerosis 20110701

• SREBP2 mediates the modulation of intestinal NPC1L1 expression by curcumin.

  American journal of physiology. Gastrointestinal and liver physiology 20110701

• Carotid intima-media thickness and ezetimibe: the end of a misunderstanding?

  Current vascular pharmacology 20110701

• Topical anti-inflammatory effect of hypocholesterolaemic drugs.

  The Journal of pharmacy and pharmacology 20110701

• Comparison of effects of morning versus evening administration of ezetimibe/simvastatin on serum cholesterol in patients with primary hypercholesterolemia.

  The Annals of pharmacotherapy 20110701

• [Pharmaco-economic optimization of cholesterol-lowering treatment with statins].

  Medicina clinica 20110625

• SHARP: a stab in the right direction in chronic kidney disease.

  Lancet (London, England) 20110625

• The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial.

  Lancet (London, England) 20110609

• Reimbursement of pharmaceuticals: reference pricing versus health technology assessment.

  The European journal of health economics : HEPAC : health economics in prevention and care 20110601

• Differential effects on inhibition of cholesterol absorption by plant stanol and plant sterol esters in apoE-/- mice.

  Cardiovascular research 20110601

• Switching from statin monotherapy to ezetimibe/simvastatin or rosuvastatin modifies the relationships between apolipoprotein B, LDL cholesterol, and non-HDL cholesterol in patients at high risk of coronary disease.

  Clinical biochemistry 20110601

• Comparison of the effects of combination atorvastatin (40 mg) + ezetimibe (10 mg) versus atorvastatin (40 mg) alone on secretory phospholipase A2 activity in patients with stable coronary artery disease or coronary artery disease equivalent.

  The American journal of cardiology 20110601

• Utility of atherosclerosis imaging in the evaluation of high-density lipoprotein-raising therapies.

  Current atherosclerosis reports 20110601

• Comparative efficacy of the addition of ezetimibe to statin vs statin titration in patients with hypercholesterolaemia: systematic review and meta-analysis.

  Current medical research and opinion 20110601

• [Efficacy and safety of ezetimibe in vascular risk units].

  Revista clinica espanola 20110601

• Hepatic Niemann-Pick C1-like 1.

  Current opinion in lipidology 20110601

• Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management.

  European heart journal 20110601

• Time-dependent impact of diabetes on mortality in patients after major lower extremity amputation: survival in a population-based 5-year cohort in Germany.

  Diabetes care 20110601

• Clinical aspects of PCSK9.

  Atherosclerosis 20110601

• Efficacy and safety of long-term ezetimibe/simvastatin treatment in patients with familial hypercholesterolemia.

  International angiology : a journal of the International Union of Angiology 20110601

• Half-dose ezetimibe add-on to statin therapy is effective in improving resistant hyperlipidaemia in Asian patients with ischaemic heart disease.

  Singapore medical journal 20110601

• Lipid lowering therapy in type 2 diabetes.

  Wiener medizinische Wochenschrift (1946) 20110601

• Therapeutic target achievement in type 2 diabetic patients after hyperglycemia, hypertension, dyslipidemia management.

  Diabetes & metabolism journal 20110601

• [After bypass surgery nearly all lipids are in the normal range. However, Lp(a) is too high, what can be done?].

  MMW Fortschritte der Medizin 20110526

• More on DSMBs.

  The New England journal of medicine 20110512

• Ezetimibe decreases SREBP-1c expression in liver and reverses hepatic insulin resistance in mice fed a high-fat diet.

  Metabolism: clinical and experimental 20110501

• Assessment of potential pharmacokinetic interactions of ezetimibe/simvastatin and extended-release niacin tablets in healthy subjects.

  European journal of clinical pharmacology 20110501

• Vitamin D intestinal absorption is not a simple passive diffusion: evidences for involvement of cholesterol transporters.

  Molecular nutrition & food research 20110501

• Statin-induced myopathy: a review and update.

  Expert opinion on drug safety 20110501

• Adherence to single-pill combination versus multiple-pill combination lipid-modifying therapy among patients with mixed dyslipidemia in a managed care population.

  Current medical research and opinion 20110501

• Safety review of combination drugs for hyperlipidemia.

  Expert opinion on drug safety 20110501

• Effects of ezetimibe added to ongoing statin therapy on C-reactive protein levels in hypercholesterolemic patients.

  Korean circulation journal 20110501

• Isolation and structure elucidation of major alkaline degradant of ezetimibe.

  Journal of pharmaceutical and biomedical analysis 20110428

• Effects of coadministered ezetimibe plus fenofibrate in mixed dyslipidemic patients with metabolic syndrome.

  Metabolic syndrome and related disorders 20110401

• Statin therapy and cataract in type 2 diabetes.

  Diabetes & metabolism 20110401

• Improved efficacy for ezetimibe and rosuvastatin by attenuating the induction of PCSK9.

  Journal of lipid research 20110401

• The effect of ezetimibe and simvastatin on monocyte cytokine release in patients with isolated hypercholesterolemia.

  Journal of cardiovascular pharmacology 20110401

• Ezetimibe treatment lowers indicators of oxidative stress in hypercholesterolemic subjects with high oxidative stress.

  Lipids 20110401

• Drug interactions between the immunosuppressant tacrolimus and the cholesterol absorption inhibitor ezetimibe in healthy volunteers.

  Clinical pharmacology and therapeutics 20110401

• Chronic administration of ezetimibe increases active glucagon-like peptide-1 and improves glycemic control and pancreatic beta cell mass in a rat model of type 2 diabetes.

  Biochemical and biophysical research communications 20110401

• Pharmacokinetics and safety of the co-administration of the antiretroviral raltegravir and the lipid-lowering drug ezetimibe in healthy volunteers.

  The Journal of antimicrobial chemotherapy 20110401

• Effects of ezetimibe on atherosclerosis in preclinical models.

  Atherosclerosis 20110401

• Statin/ezetimibe combination therapy: emerging evidence.

  Current opinion in lipidology 20110401

• Effectiveness of drug-eluting stents versus bare-metal stents in large coronary arteries in patients with acute myocardial infarction.

  Journal of Korean medical science 20110401

• Medical management of stable coronary artery disease.

  American family physician 20110401

• Achievement of recommended lipid and lipoprotein levels with combined ezetimibe/statin therapy versus statin alone in patients with and without diabetes.

  Diabetes & vascular disease research 20110401

• Achieving optimal lipid goals in patients with coronary artery disease.

  The American journal of cardiology 20110315

• Impaired aortic distensibility measured by computed tomography is associated with the severity of coronary artery disease.

  The international journal of cardiovascular imaging 20110301

• Induction of microsomal triglyceride transfer protein expression is a candidate mechanism by which ezetimibe therapy might exert beneficial effects in patients with nonalcoholic steatohepatitis.

  Journal of gastroenterology 20110301

• Variability and persistence of aspirin response in lower extremity peripheral arterial disease patients.

  Journal of vascular surgery 20110301

• Role of statins in preventing adverse cardiovascular outcomes in patients with chronic kidney disease.

  Current opinion in nephrology and hypertension 20110301

• The effect of simvastatin alone versus simvastatin plus ezetimibe on the concentration of small dense low-density lipoprotein cholesterol in subjects with primary hypercholesterolemia.

  Current medical research and opinion 20110301

• Ezetimibe and low density lipoprotein subfractions: an ongoing debate.

  Current medical research and opinion 20110301

• Lipid modification in the elderly using the combination of a statin and a cholesterol absorption inhibitor.

  Expert opinion on pharmacotherapy 20110301

• Outcome of patients with low-gradient 'severe' aortic stenosis and preserved ejection fraction.

  Circulation 20110301

• Impaired kidney allograft function following ezetimibe therapy.

  Iranian journal of kidney diseases 20110301

• The role of niacin in raising high-density lipoprotein cholesterol to reduce cardiovascular events in patients with atherosclerotic cardiovascular disease and optimally treated low-density lipoprotein cholesterol Rationale and study design. The Atherothrombosis Intervention in Metabolic syndrome with low HDL/high triglycerides: Impact on Global Health outcomes (AIM-HIGH).

  American heart journal 20110301

• The role of niacin in raising high-density lipoprotein cholesterol to reduce cardiovascular events in patients with atherosclerotic cardiovascular disease and optimally treated low-density lipoprotein cholesterol: baseline characteristics of study participants. The Atherothrombosis Intervention in Metabolic syndrome with low HDL/high triglycerides: impact on Global Health outcomes (AIM-HIGH) trial.

  American heart journal 20110301

• Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis.

  PLoS biology 20110301

• Combinations of ezetimibe with nonstatin drug regimens affecting lipid metabolism.

  Expert review of cardiovascular therapy 20110301

• Depressogenic effects of medications: a review.

  Dialogues in clinical neuroscience 20110301

• Comparison of Ezetimibe/Simvastatin 10/20 mg Versus Atorvastatin 20 mg in Achieving a Target Low Density Lipoprotein-Cholesterol Goal for Patients With Very High Risk.

  Korean circulation journal 20110301

• Perceived barriers to application of glycaemic index: valid concerns or lost in translation?

  Nutrients 20110301

• The comparative efficacy of ezetimibe added to atorvastatin 10 mg versus uptitration to atorvastatin 40 mg in subgroups of patients aged 65 to 74 years or greater than or equal to 75 years.

  Journal of geriatric cardiology : JGC 20110301

• Experimental, SOPPA(CCSD), and DFT analysis of substitutent effects on NMR 1JCF coupling constants in fluorobenzene derivatives.

  The journal of physical chemistry. A 20110224

• Ezetimibe, an inhibitor of intestinal cholesterol absorption, decreases serum level of malondialdehyde-modified low-density lipoprotein in patients with hypercholesterolemia.

  International journal of cardiology 20110203

• Enhanced spectrophotometric determination of two antihyperlipidemic mixtures containing ezetimibe in pharmaceutical preparations.

  Drug testing and analysis 20110201

• Human NPC1L1 expression is positively regulated by PPARα.

  Pharmaceutical research 20110201

• What combination therapy with a statin, if any, would you recommend?

  Current atherosclerosis reports 20110201

• The anti-ischemic and anti-anginal properties of statins.

  Current atherosclerosis reports 20110201

• Achievement of lipid targets with the combination of rosuvastatin and fenofibric Acid in patients with type 2 diabetes mellitus.

  Cardiovascular drugs and therapy 20110201

• Approach to dyslipidemia, lipodystrophy, and cardiovascular risk in patients with HIV infection.

  Current atherosclerosis reports 20110201

• Therapies targeting exogenous cholesterol uptake: new insights and controversies.

  Current atherosclerosis reports 20110201

• Comparison of fibrate, ezetimibe, low- and high-dose statin therapy for the dyslipidemia of the metabolic syndrome in a mouse model.

  Angiology 20110201

• Ezetimibe is effective in the treatment of persistent hyperlipidemia of renal allograft recipients.

  Clinical nephrology 20110201

• Lowering LDL cholesterol with margarine containing plant stanol/sterol esters: is it still relevant in 2011?

  Complementary therapies in medicine 20110201

• The effects of statin monotherapy and low-dose statin/ezetimibe on lipoprotein-associated phospholipase A₂.

  Clinical cardiology 20110201

• Combination of prescribing restrictions and policies to engineer low prices to reduce reimbursement costs.

  Expert review of pharmacoeconomics & outcomes research 20110201

• Efficacy of ezetimibe as monotherapy or combination therapy in hypercholesterolemic patients with and without diabetes.

  The journal of medical investigation : JMI 20110201

• Use of intensive lipid-lowering therapy in patients hospitalized with acute coronary syndrome: An analysis of 65,396 hospitalizations from 344 hospita participating in Get With The Guidelines (GWTG).

  American heart journal 20110201

• Phytosterols and phytosterolemia: gene-diet interactions.

  Genes & nutrition 20110201

• Lipid-lowering effects of ezetimibe and simvastatin in combination.

  Expert review of cardiovascular therapy 20110201

• Combination therapy with ezetimibe/simvastatin versus statin monotherapy for low-density lipoprotein cholesterol reduction and goal attainment in a real-world clinical setting.

  Clinical therapeutics 20110201

• Statin-associated myasthenic weakness.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20110201

• Response: a retrospective study on the efficacy of a ten-milligram dosage of atorvastatin for treatment of hypercholesterolemia in type 2 diabetes mellitus patients (korean diabetes j 2010;34:359-67).

  Diabetes & metabolism journal 20110201

• Economic evaluation of ezetimibe combined with simvastatin for the treatment of primary hypercholesterolaemia.

  Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20110201

• Ezetimibe, cardiovascular risk and atherogenic dyslipidaemia.

  Archives of medical science : AMS 20110201

• Nanocarrier for the enhanced bioavailability of a cardiovascular agent: in vitro, pharmacodynamic, pharmacokinetic and stability assessment.

  International journal of pharmaceutics 20110117

• Managing residual risk in patients receiving statin therapy.

  The Medical journal of Australia 20110103

• Managing residual risk in patients receiving statin therapy. Comment.

  The Medical journal of Australia 20110103

• Ethanol extract of fructus schisandrae decreases hepatic triglyceride level in mice fed with a high fat/cholesterol diet, with attention to acute toxicity.

  Evidence-based complementary and alternative medicine : eCAM 20110101

• Dyslipidaemia in the metabolic syndrome and type 2 diabetes: pathogenesis, priorities, pharmacotherapies.

  Expert opinion on pharmacotherapy 20110101

• Efficacy of long-term ezetimibe therapy in patients with nonalcoholic fatty liver disease.

  Journal of gastroenterology 20110101

• Niemann-pick C1-like 1 (NPC1L1) protein in intestinal and hepatic cholesterol transport.

  Annual review of physiology 20110101

• Effects of UDP-glucuronosyltransferase polymorphisms on the pharmacokinetics of ezetimibe in healthy subjects.

  European journal of clinical pharmacology 20110101

• Refsum's Disease-Use of the Intestinal Lipase Inhibitor, Orlistat, as a Novel Therapeutic Approach to a Complex Disorder.

  Journal of obesity 20110101

• A randomised placebo-controlled double-blind trial to evaluate lipid-lowering pharmacotherapy on proteolysis and inflammation in abdominal aortic aneurysms.

  European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20110101

• Comments regarding 'A randomised placebo-controlled double-blind trial to evaluate lipid-lowering pharmacotherapy on proteolysis and inflammation in abdominal aortic aneurysms'.

  European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20110101

• Ezetimibe and vascular inflammation.

  Current vascular pharmacology 20110101

• Ezetimibe and reactive oxygen species.

  Current vascular pharmacology 20110101

• Novel role of NPC1L1 in the regulation of hepatic metabolism: potential contribution of ezetimibe in NAFLD/NASH treatment.

  Current vascular pharmacology 20110101

• Ezetimibe and vascular endothelial function.

  Current vascular pharmacology 20110101

• New concept of vascular calcification and metabolism.

  Current vascular pharmacology 20110101

• Ezetimibe; more than a low density lipoprotein cholesterol lowering drug? An update after 4 years.

  Current vascular pharmacology 20110101

• Vascular protective effects of ezetimibe: seeking new therapeutic possibilities of ezetimibe in vascular disease.

  Current vascular pharmacology 20110101

• Use of NBD-cholesterol to identify a minor but NPC1L1-independent cholesterol absorption pathway in mouse intestine.

  American journal of physiology. Gastrointestinal and liver physiology 20110101

• Use of ultra high performance liquid chromatography-tandem mass spectrometry to demonstrate decreased serum statin levels after extracorporeal LDL-cholesterol elimination.

  Journal of biomedicine & biotechnology 20110101

• 'Trig-onometry': non-high-density lipoprotein cholesterol as a therapeutic target in dyslipidaemia.

  International journal of clinical practice 20110101

• Adjunctive lipid lowering therapy in the era of surrogate endpoints.

  Cardiology in review 20110101

• Standards of medical care in diabetes--2011.

  Diabetes care 20110101

• Design and characterization of nanocrystal formulations containing ezetimibe.

  Chemical & pharmaceutical bulletin 20110101

• Low density lipoprotein cholesterol is inversely correlated with abdominal visceral fat area: a magnetic resonance imaging study.

  Lipids in health and disease 20110101

• Regular physical exercise training assists in preventing type 2 diabetes development: focus on its antioxidant and anti-inflammatory properties.

  Cardiovascular diabetology 20110101

• Evaluating the effectiveness of rosuvastatin in preventing the progression of diastolic dysfunction in aortic stenosis: A substudy of the aortic stenosis progression observation measuring effects of rosuvastatin (ASTRONOMER) study.

  Cardiovascular ultrasound 20110101

• Comparative study between high-dose fluvastatin and low-dose fluvastatin and ezetimibe with regard to the effect on endothelial function in diabetic patients.

  Endocrine journal 20110101

• Cardiorenal syndrome type 4-cardiovascular disease in patients with chronic kidney disease: epidemiology, pathogenesis, and management.

  International journal of nephrology 20110101

• Considering statins for cholesterol-reduction in children if lifestyle and diet changes do not improve their health: a review of the risks and benefits.

  Vascular health and risk management 20110101

• Effects of currently prescribed LDL-C-lowering drugs on PCSK9 and implications for the next generation of LDL-C-lowering agents.

  Lipids in health and disease 20110101

• An essential role for diet in exercise-mediated protection against dyslipidemia, inflammation and atherosclerosis in ApoE⁻/⁻ mice.

  PloS one 20110101

• Subjects with molecularly defined familial hypercholesterolemia or familial defective apoB-100 are not being adequately treated.

  PloS one 20110101

• Inflammatory Signals shift from adipose to liver during high fat feeding and influence the development of steatohepatitis in mice.

  Journal of inflammation (London, England) 20110101

• ABCA1 and ABCG1 expressions are regulated by statins and ezetimibe in Caco-2 cells.

  Drug metabolism and drug interactions 20110101

• Persistent lipid abnormalities in patients treated with statins: Portuguese results of the Dyslipidemia International Study (DYSIS).

  Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20110101

• Understanding hypertriglyceridemia in women: clinical impact and management with prescription omega-3-acid ethyl esters.

  International journal of women's health 20110101

• Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes.

  Diabetes, metabolic syndrome and obesity : targets and therapy 20110101

• Use of a treatment optimization algorithm involving statin-ezetimibe combination aids in achievement of guideline-based low-density lipoprotein targets in patients with dyslipidemia at high vascular risk Guideline-based Undertaking to Improve Dyslipidemia Management in Canada (GUIDANC).

  The Canadian journal of cardiology 20110101

• Identification of common differentially expressed genes in urinary bladder cancer.

  PloS one 20110101

• Influence of polymorphisms and cholesterol-lowering treatment on SCARB1 mRNA expression.

  Journal of atherosclerosis and thrombosis 20110101

• The structure of the NPC1L1 N-terminal domain in a closed conformation.

  PloS one 20110101

• Solid self-nanoemulsifying cyclosporin A pellets prepared by fluid-bed coating: preparation, characterization and in vitro redispersibility.

  International journal of nanomedicine 20110101

• Influence of simvastatin, fenofibrate and/or ezetimibe on correlation of low-density lipoprotein and nonhigh-density lipoprotein cholesterol with apolipoprotein B in mixed dyslipidemic patients.

  Journal of clinical lipidology 20110101

• A validated densitometric method for analysis of atorvastatin calcium and metoprolol tartarate as bulk drugs and in combined capsule dosage forms.

  Journal of young pharmacists : JYP 20110101

• Rapid simultaneous determination of telmisartan, amlodipine besylate and hydrochlorothiazide in a combined poly pill dosage form by stability-indicating ultra performance liquid chromatography.

  Scientia pharmaceutica 20110101

• Dyslipidemia associated with chronic kidney disease.

  The open cardiovascular medicine journal 20110101

• Prosthetic aortic valve stenosis in end-stage renal failure.

  International journal of nephrology 20110101

• Dyslipidaemia of obesity, metabolic syndrome and type 2 diabetes mellitus: the case for residual risk reduction after statin treatment.

  The open cardiovascular medicine journal 20110101

• Pharmacological management of cardiorenal syndromes.

  International journal of nephrology 20110101

• Clinical characteristics and evaluation of LDL-cholesterol treatment of the Spanish Familial Hypercholesterolemia Longitudinal Cohort Study (SAFEHEART).

  Lipids in health and disease 20110101

• Effective therapy using voglibose for nonalcoholic steatohepatitis in a patient with insufficient dietary and exercise therapy: exploring other treatment possibilities.

  Case reports in gastroenterology 20110101

• Generation of polyclonal antibody with high avidity to rosuvastatin and its use in development of highly sensitive ELISA for determination of rosuvastatin in plasma.

  Chemistry Central journal 20110101

• Nonalcoholic Fatty liver disease: focus on lipoprotein and lipid deregulation.

  Journal of lipids 20110101

• Treating statin-intolerant patients.

  Diabetes, metabolic syndrome and obesity : targets and therapy 20110101

• Persisting thrombin activity in elderly patients with atrial fibrillation on oral anticoagulation is decreased by anti-inflammatory therapy with intensive cholesterol-lowering treatment.

  Journal of clinical lipidology 20110101

• Concordance between plasma apolipoprotein B levels and cholesterol indices among patients receiving statins and nonstatin treatment: Post-hoc analyses from the U.K. InPractice study.

  Journal of clinical lipidology 20110101

• The role of statins in chronic kidney disease.

  American journal of nephrology 20110101

• Primary prevention of coronary heart disease: integration of new data, evolving views, revised goals, and role of rosuvastatin in management. A comprehensive survey.

  Drug design, development and therapy 20110101

• The role of soluble fiber intake in patients under highly effective lipid-lowering therapy.

  Nutrition journal 20110101

• Carotid plaque regression following 6-month statin therapy assessed by 3T cardiovascular magnetic resonance: comparison with ultrasound intima media thickness.

  Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20110101

• Clinical usefulness of additional treatment with ezetimibe in patients with coronary artery disease on statin therapy. - From the viewpoint of cholesterol metabolism.-.

  Circulation journal : official journal of the Japanese Circulation Society 20110101

• Animal models of calcific aortic valve disease.

  International journal of inflammation 20110101

• Alopecia areata: a new treatment plan.

  Clinical, cosmetic and investigational dermatology 20110101

• Benefit and tolerability of the coadministration of ezetimibe and atorvastatin in acute coronary syndrome patients.

  Le Journal medical libanais. The Lebanese medical journal 20110101

• A systems biology strategy for predicting similarities and differences of drug effects: evidence for drug-specific modulation of inflammation in atherosclerosis.

  BMC systems biology 20110101

• Comparative efficacy of ezetimibe/simvastatin, rosuvastatin, and atorvastatin in uncontrolled hyperlipidemia patients.

  The American journal of managed care 20110101

• Response by sex to statin plus ezetimibe or statin monotherapy: a pooled analysis of 22,231 hyperlipidemic patients.

  Lipids in health and disease 20110101

• Where are we heading with noninvasive clinical vascular physiology? Why and how should we assess endothelial function?

  Cardiology research and practice 20110101

• Safe use of ezetimibe plus simvastatin in high-risk vascular patients (with chronic kidney disease and PAD).

  Cardiovascular journal of Africa 20110101

• Lipid-lowering therapy: who can benefit?

  Vascular health and risk management 20110101

• Potential role of differential medication use in explaining excess risk of cardiovascular events and death associated with chronic kidney disease: a cohort study.

  BMC nephrology 20110101

• Short-term effect of fenofibrate on C-reactive protein: A meta-analysis of randomized controlled trials.

  Diabetology & metabolic syndrome 20110101

• Exposure to statins and risk of common cancers: a series of nested case-control studies.

  BMC cancer 20110101

• Ezetimibe in sirolimus-associated hyperlipidemia: to add or not to add to statins?

  Annals of transplantation 20110101

• A retrospective cohort study of the potency of lipid-lowering therapy and race-gender differences in LDL cholesterol control.

  BMC cardiovascular disorders 20110101

• Ethnic differences in the prevalence of polymorphisms in CYP7A1, CYP7B1 AND CYP27A1 enzymes involved in cholesterol metabolism.

  Journal of pharmacy & bioallied sciences 20110101

• Prevalence, Predictors, and Impact of Low High-Density Lipoprotein Cholesterol on in-Hospital Outcomes Among Acute Coronary Syndrome Patients in the Middle East.

  The open cardiovascular medicine journal 20110101

• Novel microwell-based spectrophotometric assay for determination of atorvastatin calcium in its pharmaceutical formulations.

  Chemistry Central journal 20110101

• Effectiveness of Ezetimibe in Reducing the Estimated Risk for Fatal Cardiovascular Events in Hypercholesterolaemic Patients with Inadequate Lipid Control While on Statin Monotherapy as Measured by the SCORE Model.

  Advances in preventive medicine 20110101

• Homozygous familial hypercholesterolemia: case report of a rare cause of dyslipidemia.

  Pediatric endocrinology, diabetes, and metabolism 20110101

• Ezetimibe monotherapy ameliorates vascular function in patients with hypercholesterolemia through decreasing oxidative stress.

  Journal of atherosclerosis and thrombosis 20110101

• Extended release niacin-laropiprant in patients with hypercholesterolemia or mixed dyslipidemias improves clinical parameters.

  Clinical Medicine Insights. Cardiology 20110101

• Low incidence of paradoxical reductions in HDL-C levels in dyslipidemic patients treated with fenofibrate alone or in combination with ezetimibe or ezetimibe/simvastatin.

  Lipids in health and disease 20110101

• A case report and brief review of the literature on bilateral retinal infarction following cardiopulmonary bypass for coronary artery bypass grafting.

  Journal of cardiothoracic surgery 20110101

• Achievement of specified low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol apolipoprotein B, and high-sensitivity C-reactive protein levels with ezetimibe/simvastatin or atorvastatin in metabolic syndrome patients with and without atherosclerotic vascular disease (from the VYMET study).

  Journal of clinical lipidology 20110101

• Astragalus polysaccharides lowers plasma cholesterol through mechanisms distinct from statins.

  PloS one 20110101

• Statins and prevention of infections: systematic review and meta-analysis of data from large randomised placebo controlled trials.

  BMJ (Clinical research ed.) 20110101

• Development and Validation of a Reversed-phase HPLC Method for Simultaneous Determination of Aspirin, Atorvastatin Calcium and Clopidogrel Bisulphate in Capsules.

  Indian journal of pharmaceutical sciences 20110101

• RANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studies.

  PloS one 20110101

• Corneal alterations during combined therapy with cyclodextrin/allopregnanolone and miglustat in a knock-out mouse model of NPC1 disease.

  PloS one 20110101

• Mild and moderate pre-dialysis chronic kidney disease is associated with increased coronary artery calcium.

  Vascular health and risk management 20110101

• Influence of ezetimibe monotherapy on ischemia-modified albumin levels in hypercholesterolemic patients.

  Pharmacological reports : PR 20110101

• Diffuse involvement of aorta in patient with familial hyperlipidemia.

  ISRN cardiology 20110101

• Ezetimibe--a new approach in hypercholesterolemia management.

  Pharmacological reports : PR 20110101

• Ezetimibe.

  Profiles of drug substances, excipients, and related methodology 20110101

• Biological roles and therapeutic potential of hydroxy-carboxylic Acid receptors.

  Frontiers in endocrinology 20110101

• Anti-oxidant and Anti-hypercholesterolemic Activities of Wasabia japonica.

  Evidence-based complementary and alternative medicine : eCAM 20101201

• Generating ceramide from sphingomyelin by alkaline sphingomyelinase in the gut enhances sphingomyelin-induced inhibition of cholesterol uptake in Caco-2 cells.

  Digestive diseases and sciences 20101201

• Effect of ezetimibe-simvastatine over endothelial dysfunction in dyslipidemic patients: assessment by 13N-ammonia positron emission tomography.

  Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 20101201

• Attainment of Canadian and European guidelines' lipid targets with atorvastatin plus ezetimibe vs. doubling the dose of atorvastatin.

  International journal of clinical practice 20101201

• Lipoprotein(a) as a cardiovascular risk factor: current status.

  European heart journal 20101201

• 2-Azetidinone--a new profile of various pharmacological activities.

  European journal of medicinal chemistry 20101201

• Spiroimidazolidinone NPC1L1 inhibitors. Part 2: structure-activity studies and in vivo efficacy.

  Bioorganic & medicinal chemistry letters 20101201

• Lipid lowering for secondary prevention of cardiovascular disease in older adults.

  Drugs & aging 20101201

• Impact of baseline severity of aortic valve stenosis on effect of intensive lipid lowering therapy (from the SEAS study).

  The American journal of cardiology 20101201

• Use of intensive lipid-lowering therapy in patients hospitalized with acute coronary syndrome: an analysis of 65,396 hospitalizations from 344 hospitals participating in Get With The Guidelines (GWTG).

  American heart journal 20101201

• Efficacy and safety of long-term ezetimibe/simvastatin treatment in patients with familial hypercholesterolemia.

  International angiology : a journal of the International Union of Angiology 20101201

• Lack of clinically relevant drug-drug interactions when dalcetrapib is co-administered with ezetimibe.

  British journal of clinical pharmacology 20101201

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20101201

• A retrospective study on the efficacy of a ten-milligram dosage of atorvastatin for treatment of hypercholesterolemia in type 2 diabetes mellitus patients.

  Korean diabetes journal 20101201

• Effects of statins on the epicardial fat thickness in patients with coronary artery stenosis underwent percutaneous coronary intervention: comparison of atorvastatin with simvastatin/ezetimibe.

  Journal of cardiovascular ultrasound 20101201

• Effect of atorvastatin in patients with chronic heart failure - insights from randomized clinical trials.

  Archives of medical science : AMS 20101201

• Identification by whole-genome resequencing of gene defect responsible for severe hypercholesterolemia.

  Human molecular genetics 20101115

• Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12,064 survivors of myocardial infarction: a double-blind randomised trial.

  Lancet (London, England) 20101113

• The fatty acid composition of plasma cholesteryl esters and estimated desaturase activities in patients with nonalcoholic fatty liver disease and the effect of long-term ezetimibe therapy on these levels.

  Clinica chimica acta; international journal of clinical chemistry 20101111

• Effect of non-statin lipid lowering and anti-obesity drugs on LDL subfractions in patients with mixed dyslipidaemia.

  Current vascular pharmacology 20101101

• Effects of lipid-lowering drugs on adiponectin.

  Current vascular pharmacology 20101101

• Prevalence and overlap of different lipid abnormalities in statin-treated patients at high cardiovascular risk in clinical practice in Germany.

  Clinical research in cardiology : official journal of the German Cardiac Society 20101101

• Effect of ezetimibe on incretin secretion in response to the intestinal absorption of a mixed meal.

  American journal of physiology. Gastrointestinal and liver physiology 20101101

• Niemann-Pick C1-Like 1 deletion in mice prevents high-fat diet-induced fatty liver by reducing lipogenesis.

  Journal of lipid research 20101101

• Multiple mechanisms limit the accumulation of unesterified cholesterol in the small intestine of mice deficient in both ACAT2 and ABCA1.

  American journal of physiology. Gastrointestinal and liver physiology 20101101

• Cholesterol intake modulates plasma triglyceride levels in glycosylphosphatidylinositol HDL-binding protein 1-deficient mice.

  Arteriosclerosis, thrombosis, and vascular biology 20101101

• Potential therapeutic uses for ezetimibe beyond lowering LDL-c to decrease cardiovascular events.

  Diabetes, obesity & metabolism 20101101

• Long-term efficacy and safety of ezetimibe/simvastatin coadministered with extended-release niacin in hyperlipidaemic patients with diabetes or metabolic syndrome.

  Diabetes, obesity & metabolism 20101101

• [On the current debate on lowering LDL cholesterol with ezetimibe].

  Deutsche medizinische Wochenschrift (1946) 20101101

• [On the current debate on lowering LDL cholesterol with ezetimibe].

  Deutsche medizinische Wochenschrift (1946) 20101101

• Safety and efficacy of ezetimibe/simvastatin combination versus atorvastatin alone in adults ≥65 years of age with hypercholesterolemia and with or at moderately high/high risk for coronary heart disease (the VYTELD study).

  The American journal of cardiology 20101101

• Ezetimibe as a potential treatment for dyslipidemia associated with chronic renal failure and renal transplant.

  Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20101101

• Emphasizing the burden of proof: The American College of Cardiology 2008 Expert Panel Comments on the ENHANCE Trial.

  Circulation. Cardiovascular quality and outcomes 20101101

• Study of Heart and Renal Protection (SHARP): randomized trial to assess the effects of lowering low-density lipoprotein cholesterol among 9,438 patients with chronic kidney disease.

  American heart journal 20101101

• Role of ezetimibe in the prevention of cardiovascular disease: absence of evidence.

  Archives of medical research 20101101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20101101

• Annual ambient black carbon associated with shorter telomeres in elderly men: Veterans Affairs Normative Aging Study.

  Environmental health perspectives 20101101

• Effect of ezetimibe monotherapy on lipid metabolism and arterial stiffness assessed by cardio-ankle vascular index in type 2 diabetic patients.

  Journal of atherosclerosis and thrombosis 20101027

• Application of one-step liquid chromatography-electrospray tandem MS/MS and collision-induced dissociation to quantification of ezetimibe and identification of its glucuronated metabolite in human serum: A pharmacokinetic study.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015

• Ezetimibe ameliorates cardiovascular complications and hepatic steatosis in obese and type 2 diabetic db/db mice.

  The Journal of pharmacology and experimental therapeutics 20101001

• Ezetimibe reduces enlarged prostate in an animal model of benign prostatic hyperplasia.

  The Journal of urology 20101001

• HDL and LDL as therapeutic targets for cardiovascular disease prevention: the possible role of niacin.

  Nutrition, metabolism, and cardiovascular diseases : NMCD 20101001

• Reversible and non-reversible cardiovascular risk in patients treated with lipid-lowering therapy: analysis of SEAS and JUPITER trials.

  European journal of internal medicine 20101001

• Combination of fenofibrate with non-statin drug regimens.

  Current pharmaceutical design 20101001

• Ezetimibe in diabetes: more than cholesterol lowering?

  Current medical research and opinion 20101001

• Ezetimibe decreases serum amyloid A levels in HDL3 in hemodialysis patients.

  Clinical nephrology 20101001

• Effects of combined ezetimibe and simvastatin therapy as compared with simvastatin alone in patients with type 2 diabetes: a prospective randomized double-blind clinical trial: comment on Ruggenenti et al.

  Diabetes care 20101001

• Development and validation of spectrophotometeric method for simultaneous determination of simvastatin and ezetimibe in tablet formulations.

  Pakistan journal of pharmaceutical sciences 20101001

• Efficacy and safety of fenofibric acid in combination with atorvastatin and ezetimibe in patients with mixed dyslipidemia.

  American heart journal 20101001

• [High-dose statin therapy for high-risk patients].

  Herz 20101001

• Heterozygous familial hypercholesterolemia case study.

  Journal of the American Academy of Nurse Practitioners 20101001

• Are we getting to lipid targets in real life?

  Archives of medical science : AMS 20101001

• Changes in attainment of lipid goals by general practitioners and specialists in patients at high cardiovascular risk in Hungary during 2004-2008.

  Archives of medical science : AMS 20101001

• Molecular mechanisms of ezetimibe-induced attenuation of postprandial hypertriglyceridemia.

  Journal of atherosclerosis and thrombosis 20100930

• Current therapy for patients with sitosterolemia--effect of ezetimibe on plant sterol metabolism.

  Journal of atherosclerosis and thrombosis 20100930

• Managing residual risk in patients receiving statin therapy.

  The Medical journal of Australia 20100920

• Effects of ezetimibe add-on to statin therapy on adipokine production in patients with metabolic syndrome and stable vascular disease.

  Journal of cardiovascular pharmacology 20100901

• Effect of ezetimibe on carotid intimal thickness: the VYCTOR Study.

  Current atherosclerosis reports 20100901

• Effect of extended-release niacin or ezetimibe on carotid intimal thickness: the ARBITER-HALTS Study.

  Current atherosclerosis reports 20100901

• Management of statin-intolerant high-risk patients.

  Current vascular pharmacology 20100901

• Effects of combined ezetimibe and simvastatin therapy as compared with simvastatin alone in patients with type 2 diabetes: a prospective randomized double-blind clinical trial.

  Diabetes care 20100901

• The influence of PCSK9 polymorphisms on serum low-density lipoprotein cholesterol and risk of atherosclerosis.

  Current atherosclerosis reports 20100901

• [The best srategies to optimize lipid control: increasing statins dose or ezetimibe coadministration?].

  Revista clinica espanola 20100901

• [The current debate on lowering LDL cholesterol with ezetimibe].

  Deutsche medizinische Wochenschrift (1946) 20100901

• Effects of lipid-lowering drugs on reverse cholesterol transport gene expressions in peripheral blood mononuclear and HepG2 cells.

  Pharmacogenomics 20100901

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20100901

• Ultrasound diagnosis of bilateral quadriceps tendon rupture after statin use.

  The western journal of emergency medicine 20100901

• Ezetimibe, oxidized low density lipoprotein, Lp (a), and dyslipidemia.

  Journal of atherosclerosis and thrombosis 20100831

• [Genetic background of the efficacy of cholesterol absorption. The role of Niemann-Pick C1-like 1 receptor and its genetic variations in lipid metabolism].

  Orvosi hetilap 20100822

• Ezetimibe stimulates faecal neutral sterol excretion depending on abcg8 function in mice.

  FEBS letters 20100820

• Ezetimibe reverses the inhibitory effects of dietary cholesterol on mammary tumorigenesis in rats.

  International journal of cancer 20100815

• Novel nanoemulsion for minimizing variations in bioavailability of ezetimibe.

  Journal of drug targeting 20100801

• Clinical observations, molecular genetic analysis, and treatment of sitosterolemia in infants and children.

  Journal of inherited metabolic disease 20100801

• Management of hypertriglyceridemia in the diabetic patient.

  Current diabetes reports 20100801

• Ezetimibe as a potential treatment for non-alcoholic fatty liver disease: is the intestine a modulator of hepatic insulin sensitivity and hepatic fat accumulation?

  Drug discovery today 20100801

• Combination regimens with statin, niacin, and intestinally active LDL-lowering drugs: alternatives to high-dose statin therapy?

  Current opinion in lipidology 20100801

• ANCA-positive vasculitis associated with simvastatin/ezetimibe: expanding the spectrum of statin-induced autoimmunity?

  International journal of rheumatic diseases 20100801

• Ask the doctor. I have tried all of the statin drugs to lower my cholesterol, but each one has caused severe muscle pain. Are there any non-statin medications I could try using to lower my cholesterol?

  Harvard heart letter : from Harvard Medical School 20100801

• Therapeutic effect of statin on aortic stenosis: a review with meta-analysis.

  Journal of clinical pharmacy and therapeutics 20100801

• Do We Know When and How to Lower Lipoprotein(a)?

  Current treatment options in cardiovascular medicine 20100801

• Last stop before exit - hepatitis C assembly and release as antiviral drug targets.

  Viruses 20100801

• Drug treatment of hyperlipidaemia: a guide to the rational use of lipid-lowering drugs.

  Drugs 20100730

• Homozygous familial hypercholesterolaemia and treatment by LDL apheresis.

  The New Zealand medical journal 20100730

• Don't mess with the DSMB.

  The New England journal of medicine 20100729

• Effect of ezetimibe/atorvastatin combination on oxidized low density lipoprotein cholesterol in patients with coronary artery disease or coronary artery disease equivalent.

  The American journal of cardiology 20100715

• NPC1L1 and cholesterol transport.

  FEBS letters 20100702

• Targeting dyslipidemia in the metabolic syndrome: an update.

  Current vascular pharmacology 20100701

• Statins in primary biliary cirrhosis: are they safe?

  Digestive diseases and sciences 20100701

• Reduced LDL-cholesterol levels in patients with coronary artery disease are paralleled by improved endothelial function: An observational study in patients from 2003 and 2007.

  Atherosclerosis 20100701

• Improvement of endothelial damage and regeneration indexes in patients with coronary artery disease after 4 weeks of statin therapy.

  Atherosclerosis 20100701

• Ezetimibe and recent clinical trials: a look on the bright side.

  Expert opinion on drug safety 20100701

• Aortic stenosis and lipids: does intervention work?

  Current opinion in cardiology 20100701

• Incremental cholesterol reduction with ezetimibe/simvastatin, atorvastatin and rosuvastatin in UK General Practice (IN-PRACTICE): randomised controlled trial of achievement of Joint British Societies (JBS-2) cholesterol targets.

  International journal of clinical practice 20100701

• A human-type nonalcoholic steatohepatitis model with advanced fibrosis in rabbits.

  The American journal of pathology 20100701

• Advancing therapy for hypercholesterolemia.

  Expert opinion on pharmacotherapy 20100701

• Ezetimibe alone or in combination with simvastatin increases small dense low-density lipoproteins in healthy men: a randomized trial.

  European heart journal 20100701

• 2009 World Congress on the Insulin Resistance Syndrome: cardiovascular disease concepts.

  Diabetes care 20100701

• Ezetimibe anhydrate, determined from laboratory powder diffraction data.

  Acta crystallographica. Section C, Crystal structure communications 20100701

• Money, money, money.

  Drug and therapeutics bulletin 20100701

• [Hyperlipoproteinaemia and dyslipoproteinaemia II. Therapy: non-pharmacological and pharmacological approaches].

  Vnitrni lekarstvi 20100701

• Rosuvastatin but not ezetimibe improves endothelial function in patients with heart failure, by mechanisms independent of lipid lowering.

  International journal of cardiology 20100625

• The ARBITER 6-HALTS Trial (Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol 6-HDL and LDL Treatment Strategies in Atherosclerosis): final results and the impact of medication adherence, dose, and treatment duration.

  Journal of the American College of Cardiology 20100615

• Observed and predicted reduction of ischemic cardiovascular events in the Simvastatin and Ezetimibe in Aortic Stenosis trial.

  The American journal of cardiology 20100615

• Effects of atorvastatin 20 mg, rosuvastatin 10 mg, and atorvastatin/ezetimibe 5 mg/5 mg on lipoproteins and glucose metabolism.

  Journal of cardiovascular pharmacology and therapeutics 20100601

• Improved endothelial function with simvastatin but unchanged insulin sensitivity with simvastatin or ezetimibe.

  Metabolism: clinical and experimental 20100601

• Intestinal absorption of gamma-tocotrienol is mediated by Niemann-Pick C1-like 1: in situ rat intestinal perfusion studies.

  Drug metabolism and disposition: the biological fate of chemicals 20100601

• Pharmacokinetic and pharmacodynamic interactions between the immunosuppressant sirolimus and the lipid-lowering drug ezetimibe in healthy volunteers.

  Clinical pharmacology and therapeutics 20100601

• Molecular pathways and agents for lowering LDL-cholesterol in addition to statins.

  Pharmacology & therapeutics 20100601

• Usefulness of exercise-stress echocardiography for risk stratification of true asymptomatic patients with aortic valve stenosis.

  European heart journal 20100601

• Combination of acarbose and ezetimibe prevents non-alcoholic fatty liver disease: a break of intestinal insulin resistance?

  Journal of hepatology 20100601

• Efficacy of ezetimibe for the treatment of non-alcoholic steatohepatitis: An open-label, pilot study.

  Hepatology research : the official journal of the Japan Society of Hepatology 20100601

• Retrospective, observation study: Quantitative and qualitative effect of ezetimibe and HMG-CoA reductase inhibitors on LDL-cholesterol: are there disappearance thresholds for small, dense LDL and IDL?

  Recent patents on cardiovascular drug discovery 20100601

• Asymmetric septal hypertrophy - a marker of hypertension in aortic stenosis (a SEAS substudy).

  Blood pressure 20100601

• Statins for calcific aortic valve stenosis: into oblivion after SALTIRE and SEAS? An extensive review from bench to bedside.

  Current problems in cardiology 20100601

• Model of intestinal chylomicron over-production and ezetimibe treatment: impact on the retention of cholesterol in arterial vessels.

  Atherosclerosis. Supplements 20100601

• Targets for current pharmacologic therapy in cholesterol gallstone disease.

  Gastroenterology clinics of North America 20100601

• Does the blood pressure-lowering effect of statins contribute to their beneficial cardiovascular effects?

  Expert review of cardiovascular therapy 20100601

• Systematic review on evidence of the effectiveness of cholesterol-lowering drugs.

  Advances in therapy 20100601

• Impact of pressure recovery on echocardiographic assessment of asymptomatic aortic stenosis: a SEAS substudy.

  JACC. Cardiovascular imaging 20100601

• The role of ezetimibe in the prevention of cardiovascular disease: where do we stand after ARBITER 6-HALTS.

  Nutrition, metabolism, and cardiovascular diseases : NMCD 20100601

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20100601

• Ezetimibe. The French authorities gradually confirm the lack of benefit.

  Prescrire international 20100601

• Ezetimibe: excess cancer incidence in a comparative trial.

  Prescrire international 20100601

• Why do we need multifunctional neuroprotective and neurorestorative drugs for Parkinson's and Alzheimer's diseases as disease modifying agents.

  Experimental neurobiology 20100601

• Effect of obesity on left ventricular mass and systolic function in patients with asymptomatic aortic stenosis (a Simvastatin Ezetimibe in Aortic Stenosis [SEAS] substudy).

  The American journal of cardiology 20100515

• Pleiotropic effects of ezetimibe: do they really exist?

  European journal of pharmacology 20100510

• Effects of rimonabant, as monotherapy and in combination with fenofibrate or ezetimibe, on plasma adipokine levels: a pilot study.

  Angiology 20100501

• Structural elucidation of a process-related impurity in ezetimibe by LC/MS/MS and NMR.

  Journal of pharmaceutical and biomedical analysis 20100501

• A humanized UGT1 mouse model expressing the UGT1A1*28 allele for assessing drug clearance by UGT1A1-dependent glucuronidation.

  Drug metabolism and disposition: the biological fate of chemicals 20100501

• Relationships between metabolic syndrome and other baseline factors and the efficacy of ezetimibe/simvastatin and atorvastatin in patients with type 2 diabetes and hypercholesterolemia.

  Diabetes care 20100501

• Effect of ezetimibe on hepatic fat, inflammatory markers, and apolipoprotein B-100 kinetics in insulin-resistant obese subjects on a weight loss diet.

  Diabetes care 20100501

• Effect of atorvastatin and ezetimibe treatment on serum lipid profile and oxidative state in rats fed with a high-cholesterol diet.

  The American journal of the medical sciences 20100501

• Cost-effectiveness of rosuvastatin versus ezetimibe/simvastatin in managing dyslipidemic patients in Mexico.

  Current medical research and opinion 20100501

• Ezetimibe therapy and its influence on oxidative stress and fibrinolytic activity.

  Southern medical journal 20100501

• The effects of ezetimibe and/or orlistat on triglyceride-rich lipoprotein metabolism in obese hypercholesterolemic patients.

  Lipids 20100501

• Therapy: raising HDL cholesterol levels: a flight of Icarus?

  Nature reviews. Endocrinology 20100501

• Colesevelam lowers glucose and lipid levels in type 2 diabetes: the clinical evidence.

  Diabetes, obesity & metabolism 20100501

• An update on the IMProved reduction of outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) design.

  American heart journal 20100501

• Efficacy of cholesterol uptake inhibition added to statin therapy among subjects following a low-carbohydrate diet: a randomized controlled trial.

  American heart journal 20100501

• Effects of combined therapy with ezetimibe plus simvastatin after drug-eluting stent implantation in a porcine coronary restenosis model.

  Journal of Korean medical science 20100501

• Approach to the patient who is intolerant of statin therapy.

  The Journal of clinical endocrinology and metabolism 20100501

• [Advances in cholesterol-lowering interventions].

  Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20100501

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20100501

• Impact of Fenofibrate on Type 2 Diabetes Patients with Features of the Metabolic Syndrome: Subgroup Analysis From FIELD.

  Current cardiology reviews 20100501

• A SNP of NPC1L1 affects cholesterol absorption in Japanese.

  Journal of atherosclerosis and thrombosis 20100430

• Characterization of low density lipoprotein receptor (LDLR) gene mutations in Albania.

  Archives of medical science : AMS 20100430

• Ezetimbe as potential treatment for cholesterol gallstones: the need for clinical trials.

  World journal of gastroenterology 20100407

• Managing residual risk in patients receiving statin therapy.

  The Medical journal of Australia 20100405

• Baseline cholesterol absorption and the response to ezetimibe/simvastatin therapy: a post-hoc analysis of the ENHANCE trial.

  Journal of lipid research 20100401

• Study of surfactant combinations and development of a novel nanoemulsion for minimising variations in bioavailability of ezetimibe.

  Colloids and surfaces. B, Biointerfaces 20100401

• The catalytic and protein-protein interaction domains are required for APM1 function.

  Plant physiology 20100401

• ARBITER 6-HALTS. Does it have the power to settle all matters?

  Therapeutic advances in cardiovascular disease 20100401

• Colesevelam added to combination therapy with a statin and ezetimibe in patients with familial hypercholesterolemia: a 12-week, multicenter, randomized, double-blind, controlled trial.

  Clinical therapeutics 20100401

• Systematic review: Very-low-strength evidence suggests that combining ezetimibe or fibrate with statins is no more effective than high-dose statin monotherapy for reducing all-cause mortality.

  Evidence-based medicine 20100401

• [Problems with statins and the marketing of these medications].

  Revista medica de Chile 20100401

• Can we reduce the cardiovascular risk in peritoneal dialysis patients?

  Indian journal of nephrology 20100401

• Myriocin-mediated up-regulation of hepatocyte apoA-I synthesis is associated with ERK inhibition.

  Clinical science (London, England : 1979) 20100330

• Niacin compared with ezetimibe.

  The New England journal of medicine 20100318

• Niacin compared with ezetimibe.

  The New England journal of medicine 20100318

• Niacin compared with ezetimibe.

  The New England journal of medicine 20100318

• Niacin compared with ezetimibe.

  The New England journal of medicine 20100318

• [How far the rates of cholesterol have to be lowered in primary prevention?].

  Revue medicale suisse 20100310

• [Statins and muscular side-effects].

  Revue medicale suisse 20100310

• Evaluation of cholesterol lowering treatment of patients with familial hypercholesterolemia: a large cross-sectional study in The Netherlands.

  Atherosclerosis 20100301

• Cost-effectiveness analysis of the use of a high-intensity statin compared to a low-intensity statin in the management of patients with familial hypercholesterolaemia.

  Current medical research and opinion 20100301

• Differential effects of fluvastatin alone or in combination with ezetimibe on lipoprotein subfractions in patients at high risk of coronary events.

  European journal of clinical investigation 20100301

• Ezetimibe added to atorvastatin compared with doubling the atorvastatin dose in patients at high risk for coronary heart disease with diabetes mellitus, metabolic syndrome or neither.

  Diabetes, obesity & metabolism 20100301

• Prospective drug safety monitoring using the UK primary-care General Practice Research Database: theoretical framework, feasibility analysis and extrapolation to future scenarios.

  Drug safety 20100301

• Safety and efficacy of ezetimibe added to atorvastatin versus up titration of atorvastatin to 40 mg in Patients > or = 65 years of age (from the ZETia in the ELDerly [ZETELD] study).

  The American journal of cardiology 20100301

• Management of dyslipidemia in people with type 2 diabetes mellitus.

  Reviews in endocrine & metabolic disorders 20100301

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20100301

• The SEAS Trial.

  Current cardiology reports 20100301

• Raising highly desirable lipoprotein versus lowering deleterious lipoprotein.

  Expert review of clinical pharmacology 20100301

• Ezetimibe ameliorates metabolic disorders and microalbuminuria in patients with hypercholesterolemia.

  Journal of atherosclerosis and thrombosis 20100226

• Is the control of dietary cholesterol intake sufficiently effective to ameliorate nonalcoholic fatty liver disease?

  World journal of gastroenterology 20100221

• Long-term safety and efficacy of triple combination ezetimibe/simvastatin plus extended-release niacin in patients with hyperlipidemia.

  The American journal of cardiology 20100215

• Combined therapy in the treatment of dyslipidemia.

  Fundamental & clinical pharmacology 20100201

• Impact of hypertension on left ventricular structure in patients with asymptomatic aortic valve stenosis (a SEAS substudy).

  Journal of hypertension 20100201

• Indices of cholesterol metabolism and relative responsiveness to ezetimibe and simvastatin.

  The Journal of clinical endocrinology and metabolism 20100201

• Prediction of cardiovascular event risk reduction from lipid changes associated with high potency dyslipidemia therapy.

  Current medical research and opinion 20100201

• Ezetimibe effect on bone mineral density and markers of bone formation and resorption.

  Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20100201

• Effects of ezetimibe on remnant-like particle cholesterol, lipoprotein (a), and oxidized low-density lipoprotein in patients with dyslipidemia.

  Journal of atherosclerosis and thrombosis 20100201

• The effects of ezetimibe on surrogate markers of cholesterol absorption and synthesis in Japanese patients with dyslipidemia.

  Journal of atherosclerosis and thrombosis 20100201

• Functional assessment of HDL: Moving beyond static measures for risk assessment.

  Cardiovascular drugs and therapy 20100201

• Simultaneous determination of ezetimibe and simvastatin in pharmaceutical preparations by MEKC.

  Journal of chromatographic science 20100201

• Initiatives to enhance the quality and efficiency of statin and PPI prescribing in the UK: impact and implications.

  Expert review of pharmacoeconomics & outcomes research 20100201

• Measuring hsCRP--an important part of a comprehensive risk profile or a clinically redundant practice?

  PLoS medicine 20100201

• Ezetimibe-induced relapsing polymyositis.

  The Journal of rheumatology 20100201

• I have had trouble controlling my cholesterol with a statin alone. Should I consider prescription niacin?

  The Johns Hopkins medical letter health after 50 20100201

• Regulation of glucose control in people with type 2 diabetes: a review and consensus.

  Korean diabetes journal 20100201

• Dietary phospholipids and intestinal cholesterol absorption.

  Nutrients 20100201

• Cholesterol drug lowers LDL-C levels but again fails to show clinical benefit.

  JAMA 20100120

• Statin therapy and aortic stenosis: a systematic review of the effects of statin therapy on aortic stenosis.

  American journal of therapeutics 20100101

• Statins and cancer: a potential link?

  American journal of therapeutics 20100101

• Synergistic influence of Abcb1 and Abcc2 on disposition and sterol lowering effects of ezetimibe in rats.

  Journal of pharmaceutical sciences 20100101

• A new method for measurement of total plasma PCSK9: clinical applications.

  Journal of lipid research 20100101

• Co-administration of ezetimibe enhances proteinuria-lowering effects of pitavastatin in chronic kidney disease patients partly via a cholesterol-independent manner.

  Pharmacological research 20100101

• Myocardial deformation in aortic valve stenosis: relation to left ventricular geometry.

  Heart (British Cardiac Society) 20100101

• Pleiotropic effects with equivalent low-density lipoprotein cholesterol reduction: comparative study between simvastatin and simvastatin/ezetimibe coadministration.

  Journal of cardiovascular pharmacology 20100101

• Population-based health-economic evaluation of the secondary prevention of coronary heart disease in Finland.

  Current medical research and opinion 20100101

• Transporters as drug targets: discovery and development of NPC1L1 inhibitors.

  Clinical pharmacology and therapeutics 20100101

• Fluvastatin/fenofibrate vs. simvastatin/ezetimibe in patients with metabolic syndrome: different effects on LDL-profiles.

  European journal of clinical investigation 20100101

• Cholesterol absorption and metabolism.

  Methods in molecular biology (Clifton, N.J.) 20100101

• Medicinal chemistry of drugs used in diabetic cardiomyopathy.

  Current medicinal chemistry 20100101

• Standards of medical care in diabetes--2010.

  Diabetes care 20100101

• Rosuvastatin-associated adverse effects and drug-drug interactions in the clinical setting of dyslipidemia.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20100101

• Treatment of cyclic vomiting syndrome with co-enzyme Q10 and amitriptyline, a retrospective study.

  BMC neurology 20100101

• Hair growth in patients alopecia areata totalis after treatment with simvastatin and ezetimibe.

  Journal of drugs in dermatology : JDD 20100101

• Efficacy of simvastatin or ezetimibe on tissue factor, von Willebrand's factor and C-reactive protein in patients with hypercholesterolaemia.

  Archives of cardiovascular diseases 20100101

• Decreased NPC1L1 expression in the liver from Chinese female gallstone patients.

  Lipids in health and disease 20100101

• [Ezetimibe: caution in the face of doubt].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20100101

• Efficacy and safety of ezetimibe for Japanese patients with dyslipidaemia: The ESSENTIAL Study.

  Clinical drug investigation 20100101

• Two years after molecular diagnosis of familial hypercholesterolemia: majority on cholesterol-lowering treatment but a minority reaches treatment goal.

  PloS one 20100101

• System-dependent outcomes during the evaluation of drug candidates as inhibitors of cytochrome P450 (CYP) and uridine diphosphate glucuronosyltransferase (UGT) enzymes: human hepatocytes versus liver microsomes versus recombinant enzymes.

  Drug metabolism and pharmacokinetics 20100101

• Protein mediators of sterol transport across intestinal brush border membrane.

  Sub-cellular biochemistry 20100101

• NPC1L1 inhibitor ezetimibe is a reliable therapeutic agent for non-obese patients with nonalcoholic fatty liver disease.

  Lipids in health and disease 20100101

• Current status and future directions in lipid management: emphasizing low-density lipoproteins, high-density lipoproteins, and triglycerides as targets for therapy.

  Vascular health and risk management 20100101

• Endothelial progenitor cells: what use for the cardiologist?

  Journal of angiogenesis research 20100101

• LDL = 5: Virtues and dangers of multidrug therapy of low-density lipoprotein cholesterol.

  Preventive cardiology 20100101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20100101

• Reporting bias in medical research - a narrative review.

  Trials 20100101

• Curcumin inhibits cholesterol uptake in Caco-2 cells by down-regulation of NPC1L1 expression.

  Lipids in health and disease 20100101

• Critical appraisal of laropiprant and extended-release niacin combination in the management of mixed dyslipidemias and primary hypercholesterolemia.

  Therapeutics and clinical risk management 20100101

• Therapeutic options to further lower C-reactive protein for patients on statin treatment.

  Current atherosclerosis reports 20100101

• Management of the patient with statin intolerance.

  Current atherosclerosis reports 20100101

• The estimated GFR, but not the stage of diabetic nephropathy graded by the urinary albumin excretion, is associated with the carotid intima-media thickness in patients with type 2 diabetes mellitus: a cross-sectional study.

  Cardiovascular diabetology 20100101

• Ezetimibe + simvastatin versus doubling the dose of simvastatin in high cardiovascular risk diabetics: a multicenter, randomized trial (the LEAD study).

  Cardiovascular diabetology 20100101

• Atorvastatin as a potential anti-malarial drug: in vitro synergy in combinational therapy with quinine against Plasmodium falciparum.

  Malaria journal 20100101

• Synergistic effect of simvastatin and ezetimibe on lipid and pro-inflammatory profiles in pre-diabetic subjects.

  Diabetology & metabolic syndrome 20100101

• Fenofibric acid: a new fibrate approved for use in combination with statin for the treatment of mixed dyslipidemia.

  Vascular health and risk management 20100101

• Modified intention to treat reporting in randomised controlled trials: systematic review.

  BMJ (Clinical research ed.) 20100101

• Projected cost-effectiveness of ezetimibe/simvastatin compared with doubling the statin dose in the United Kingdom: findings from the INFORCE study.

  Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20100101

• Gene activation regresses atherosclerosis, promotes health, and enhances longevity.

  Lipids in health and disease 20100101

• Lipoprotein-associated phospholipase A2 mass is significantly reduced in dyslipidemic patients treated with lifestyle modification and combination lipid-modifying drug therapy.

  Preventive cardiology 20100101

• Dual inhibition, newer paradigms for cholesterol lowering.

  American journal of therapeutics 20100101

• Determination of immuno-reactive rabbit apolipoprotein B-48 in serum by ELISA.

  Experimental animals 20100101

• Ezetimibe/simvastatin vs simvastatin in coronary heart disease patients with or without diabetes.

  Lipids in health and disease 20100101

• Impact of medical therapy on atheroma volume measured by different cardiovascular imaging modalities.

  Cardiology research and practice 20100101

• The Role of Peroxisome Proliferator-Activated Receptor beta/delta on the Inflammatory Basis of Metabolic Disease.

  PPAR research 20100101

• Metabolic syndrome, dyslipidemia, hypertension and type 2 diabetes in youth: from diagnosis to treatment.

  Diabetology & metabolic syndrome 20100101

• Differential expression of intestinal genes in opossums with high and low responses to dietary cholesterol.

  Journal of nutrition and metabolism 20100101

• Lipid-lowering effects of ezetimibe for hypercholesterolemic patients with and without type 2 diabetes mellitus.

  Endocrine journal 20100101

• Animal models of ischemic stroke. Part one: modeling risk factors.

  The open neurology journal 20100101

• Identification of novel inhibitors of dietary lipid absorption using zebrafish.

  PloS one 20100101

• Palmaria palmata (Dulse) as an unusual maritime aetiology of hyperkalemia in a patient with chronic renal failure: a case report.

  Journal of medical case reports 20100101

• Stability Indicating RP-HPLC Method for Simultaneous Determination of Simvastatin and Ezetimibe from Tablet Dosage Form.

  Indian journal of pharmaceutical sciences 20100101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20100101

• Recent advances in the management of chronic stable angina II. Anti-ischemic therapy, options for refractory angina, risk factor reduction, and revascularization.

  Vascular health and risk management 20100101

• Subclinical atherosclerosis: evolving role of carotid intima-media thickness.

  Preventive cardiology 20100101

• Efficacy and safety of ezetimibe in patients undergoing hemodialysis.

  Endocrine journal 20100101

• Determination of rosuvastatin and ezetimibe in a combined tablet dosage form using high-performance column liquid chromatography and high-performance thin-layer chromatography.

  Journal of AOAC International 20100101

• Reaching target LDL cholesterol has become more affordable with launch of ezetimibe/simvastatin combination in South Africa.

  Cardiovascular journal of Africa 20100101

• The relationships of markers of cholesterol homeostasis with carotid intima-media thickness.

  PloS one 20100101

• Ezetimibe/simvastatin 10/20 mg versus rosuvastatin 10 mg in high-risk hypercholesterolemic patients stratified by prior statin treatment potency.

  Lipids in health and disease 20100101

• Achieving lipid targets in adults with type 2 diabetes: the Stop Atherosclerosis in Native Diabetics Study.

  Journal of clinical lipidology 20100101

• Niacin or ezetimibe for patients with, or at risk of coronary heart disease.

  Clinical Medicine Insights. Cardiology 20100101

• Hypercholesterolemia and microvascular dysfunction: interventional strategies.

  Journal of inflammation (London, England) 20100101

• The cost effectiveness of statin therapies in Spain in 2010, after the introduction of generics and reference prices.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20100101

• Are post-treatment low-density lipoprotein subclass pattern analyses potentially misleading?

  Lipids in health and disease 20100101

• Attainment of low-density lipoprotein cholesterol goals in coronary artery disease.

  Journal of clinical lipidology 20100101

• Ezetimibe/simvastatin 10/20 mg versus simvastatin 40 mg in coronary heart disease patients.

  Journal of clinical lipidology 20100101

• Report of simultaneous acute pancreatitis and acute hepatitis in a patient taking ezetimibe/simvastatin.

  Journal of clinical lipidology 20100101

• Comments on the Ezetimibe debate in Chicago.

  Journal of clinical lipidology 20100101

• Familial hypercholesterolemia: current treatment options and patient selection for low-density lipoprotein apheresis.

  Journal of clinical lipidology 20100101

• Insights from recent meta-analysis: role of high-density lipoprotein cholesterol in reducing cardiovascular events and rates of atherosclerotic disease progression.

  Journal of clinical lipidology 20100101

• Switching from high-efficacy lipid-lowering therapies to simvastatin and low-density lipoprotein cholesterol goal attainment in coronary heart disease/coronary heart disease-equivalent patients.

  Journal of clinical lipidology 20100101

• An evaluation of alanine transaminase and creatine kinase elevations with the use of ezetimibe in an ambulatory care setting.

  Journal of clinical lipidology 20100101

• Incidental cardiac findings on computed tomography imaging of the thorax.

  BMC research notes 20100101

• Combination therapy of statin and ezetimibe for the treatment of familial hypercholesterolemia.

  Vascular health and risk management 20100101

• Pitavastatin approved for treatment of primary hypercholesterolemia and combined dyslipidemia.

  Vascular health and risk management 20100101

• LDLR-Gene therapy for familial hypercholesterolaemia: problems, progress, and perspectives.

  International archives of medicine 20100101

• Antioxidant and hypolipidemic activity of Kumbhajatu in hypercholesterolemic rats.

  International journal of Ayurveda research 20100101

• Treatment of dyslipidemia in patients with type 2 diabetes.

  Lipids in health and disease 20100101

• Recent advances in preventing cardiovascular disorders by managing lipid levels.

  F1000 medicine reports 20100101

• Optimal management of familial hypercholesterolemia: treatment and management strategies.

  Vascular health and risk management 20100101

• Hepatic accumulation of intestinal cholesterol is decreased and fecal cholesterol excretion is increased in mice fed a high-fat diet supplemented with milk phospholipids.

  Nutrition & metabolism 20100101

• Quantitative analysis of the cholesterol-lowering drugs ezetimibe and simvastatin in pure powder, binary mixtures, and a combined dosage form by spectrophotometry, chemometry, and high-performance column liquid chromatography.

  Journal of AOAC International 20100101

• Efficacy and safety of ezetimibe and low-dose simvastatin as primary treatment for dyslipidemia in peritoneal dialysis patients.

  Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20100101

• Primary prevention of CVD: treating dyslipidaemia.

  BMJ clinical evidence 20100101

• Pleiotropic effects of rosuvastatin on microvascular function in type 2 diabetes.

  Diabetes, metabolic syndrome and obesity : targets and therapy 20100101

• Lipid Metabolism and Cardiovascular Risk in HIV-1 Infection and HAART: Present and Future Problems.

  Cholesterol 20100101

• Cardiovascular and smooth muscle pharmacology in the next decade.

  Frontiers in pharmacology 20100101

• Safety and efficacy of laropiprant and extended-release niacin combination in the management of mixed dyslipidemias and primary hypercholesterolemia.

  Drug, healthcare and patient safety 20100101

• A patient's informative mistake: niacin is very effective in correcting dyslipidaemia.

  BMJ case reports 20100101

• A review on the rationale and clinical use of concomitant rosuvastatin and fenofibrate/fenofibric acid therapy.

  Clinical pharmacology : advances and applications 20100101

• Pharmacological management of metabolic syndrome and its lipid complications.

  Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20100101

• [Statin plus niacin or ezetimibe? What combination for which patients?].

  MMW Fortschritte der Medizin 20091203

• Ezetimibe decreases serum levels of asymmetric dimethylarginine (ADMA) and ameliorates renal injury in non-diabetic chronic kidney disease patients in a cholesterol-independent manner.

  Pharmacological research 20091201

• High resolution magnetic resonance imaging in atherosclerotic mice treated with ezetimibe.

  The international journal of cardiovascular imaging 20091201

• Statins, fibrates, nicotinic acid, cholesterol absorption inhibitors, anion-exchange resins, omega-3 fatty acids: which drugs for which patients?

  Fundamental & clinical pharmacology 20091201

• Efficacy and safety of ezetimibe plus orlistat or rimonabant in statin-intolerant nondiabetic overweight/obese patients with dyslipidemia.

  Journal of cardiovascular pharmacology and therapeutics 20091201

• The impact of ezetimibe on endothelial function and other markers of cardiovascular risk.

  The Annals of pharmacotherapy 20091201

• Low-density lipoprotein cholesterol reduction and goal achievement with ezetimibe/simvastatin versus atorvastatin or rosuvastatin in patients with diabetes, metabolic syndrome, or neither disease, stratified by National Cholesterol Education Program risk category.

  Metabolic syndrome and related disorders 20091201

• Policies to enhance the efficiency of prescribing in the Spanish Catalan region: impact and future direction.

  Expert review of pharmacoeconomics & outcomes research 20091201

• Safety and efficacy of combined ezetimibe/simvastatin treatment and simvastatin monotherapy in patients with non-alcoholic fatty liver disease.

  Medical science monitor : international medical journal of experimental and clinical research 20091201

• Xanthomas associated with homozygous familial hypercholesterolemia.

  Pharmacotherapy 20091201

• Efficacy of combination drug pulse therapy in maintaining lipid levels in patients intolerant of daily statin use.

  Journal of clinical hypertension (Greenwich, Conn.) 20091201

• [Ezetimibe (Ezetrol) in patients with diabetes].

  Revue medicale de Liege 20091201

• Potential of ezetimibe in memory deficits associated with dementia of Alzheimer's type in mice.

  Indian journal of pharmacology 20091201

• The HALTS trial--halting atherosclerosis or halted too early?

  The New England journal of medicine 20091126

• Extended-release niacin or ezetimibe and carotid intima-media thickness.

  The New England journal of medicine 20091126

• Statin therapy with ezetimibe or niacin in high-risk patients.

  The New England journal of medicine 20091126

• Systematic review: comparative effectiveness and harms of combination therapy and monotherapy for dyslipidemia.

  Annals of internal medicine 20091103

• A novel cholesterol absorption inhibitor, ezetimibe, decreases adipose-derived and vascular PAI-1 expression in vivo.

  Thrombosis research 20091101

• Regulation of steroid 5-alpha reductase type 2 (Srd5a2) by sterol regulatory element binding proteins and statin.

  Experimental cell research 20091101

• Lipid lowering versus pleiotropic effects of statins on skin microvascular function in patients with dysglycaemia and coronary artery disease.

  Journal of internal medicine 20091101

• Inhibition of hepatic Niemann-Pick C1-like 1 improves hepatic insulin resistance.

  American journal of physiology. Endocrinology and metabolism 20091101

• Moderately decreased cholesterol absorption rates are associated with a large atheroprotective effect.

  Arteriosclerosis, thrombosis, and vascular biology 20091101

• Burkholderia cenocepacia: a new biocatalyst for efficient bioreduction of ezetimibe intermediate.

  Journal of industrial microbiology & biotechnology 20091101

• A multi-center, open label, crossover designed prospective study evaluating the effects of lipid lowering treatment on steroid synthesis in patients with Type 2 diabetes (MODEST Study).

  Journal of endocrinological investigation 20091101

• Hypertension and diabetes: should we treat early surrogates? What are the cons?

  Diabetes care 20091101

• American Diabetes Association indications for statins in diabetes: is there evidence?

  Diabetes care 20091101

• Ezetimibe/simvastatin.

  Expert opinion on drug safety 20091101

• Lipid disorders.

  JAAPA : official journal of the American Academy of Physician Assistants 20091101

• Short-term ezetimibe is well tolerated and effective in combination with statin therapy to treat elevated LDL cholesterol in HIV-infected patients.

  AIDS (London, England) 20091023

• Rapid and sensitive simultaneous determination of ezetimibe and simvastatin from their combination drug products by monolithic silica high-performance liquid chromatographic column.

  Journal of pharmaceutical and biomedical analysis 20091015

• Changes in cholesterol absorption and cholesterol synthesis caused by ezetimibe and/or simvastatin in men.

  Journal of lipid research 20091001

• Peroxisome proliferator-activated receptor delta activation leads to increased transintestinal cholesterol efflux.

  Journal of lipid research 20091001

• At sea with SEAS: the first clinical endpoint trial for ezetimibe, treatment of patients with mild to moderate aortic stenosis, ends with mixed results and more controversy.

  Heart, lung & circulation 20091001

• Naringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDL receptor-null mice with diet-induced insulin resistance.

  Diabetes 20091001

• Low LDL cholesterol, albuminuria, and statins for the risk of cancer in type 2 diabetes: the Hong Kong diabetes registry.

  Diabetes care 20091001

• Clinical experience with ezetimibe/simvastatin in a Mediterranean population.

  Current medical research and opinion 20091001

• Ezetimibe inhibits expression of acid sphingomyelinase in liver and intestine.

  Lipids 20091001

• [LDL-cholesterol goals and changes in C reactive protein in high coronary risk patients].

  Revista clinica espanola 20091001

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20091001

• Usefulness of statin-ezetimibe combination to reduce the care gap in dyslipidemia management in patients with a high risk of atherosclerotic disease.

  The American journal of cardiology 20090915

• Steatocholecystitis and fatty gallbladder disease.

  Digestive diseases and sciences 20090901

• Effect of ezetimibe/simvastatin compared with atorvastatin on lipoprotein subclasses in patients with type 2 diabetes and hypercholesterolaemia.

  Diabetes, obesity & metabolism 20090901

• The role of transporters in the pharmacokinetics of orally administered drugs.

  Pharmaceutical research 20090901

• Long-term combination therapy of ezetimibe and acarbose for non-alcoholic fatty liver disease.

  Journal of hepatology 20090901

• Multiple strategies for the preparation of a sulfur-35 labeled NPC1L1 radioligand.

  Bioorganic & medicinal chemistry letters 20090901

• Lipid-lowering drugs and risk for cancer.

  Current atherosclerosis reports 20090901

• Lipid lowering and aortic valve disease.

  Current atherosclerosis reports 20090901

• Increased epistaxis with use of ezetimibe/simvastatin.

  The Annals of pharmacotherapy 20090901

• The mechanism and mitigation of niacin-induced flushing.

  International journal of clinical practice 20090901

• Letter by Westerink and Visseren regarding article, 'Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation'.

  Circulation 20090901

• Letter by Tershakovec et al regarding article, 'Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation'.

  Circulation 20090901

• Letter by Settergren et al regarding article, 'Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation'.

  Circulation 20090901

• The efficacy and safety of ezetimibe and low-dose simvastatin as a primary treatment for dyslipidemia in renal transplant recipients.

  The Korean journal of internal medicine 20090901

• The Vytorin on Carotid-Media Thickness and Overall Arterial Rigidity (VYCTOR) study.

  Expert review of cardiovascular therapy 20090901

• Cholinesterase inhibitors and hospitalization for bradycardia: a population-based study.

  PLoS medicine 20090901

• Investigation of beta-carotene and lutein transport in Caco-2 cells: carotenoid-carotenoid interactions and transport inhibition by ezetimibe.

  International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20090901

• Premature release of data from clinical trials of ezetimibe.

  The New England journal of medicine 20090813

• Membrane topology of human NPC1L1, a key protein in enterohepatic cholesterol absorption.

  Journal of lipid research 20090801

• Complex pharmacokinetic behavior of ezetimibe depends on abcc2, abcc3, and abcg2.

  Drug metabolism and disposition: the biological fate of chemicals 20090801

• Ezetimibe improves postprandial hyperlipidaemia in patients with type IIb hyperlipidaemia.

  European journal of clinical investigation 20090801

• Update on patented cholesterol absorption inhibitors.

  Expert opinion on therapeutic patents 20090801

• Ezetimibe--an update.

  Drug and therapeutics bulletin 20090801

• Familial hypercholesterolaemia: different perspectives.

  Nursing standard (Royal College of Nursing (Great Britain) : 1987) 20090801

• Effects of lifestyle counseling and combination lipid-modifying therapy on lipoprotein-associated phospholipase A2 mass concentration.

  Journal of clinical lipidology 20090801

• Inhibition of intestinal absorption of cholesterol by surface-modified nanostructured aluminosilicate compounds.

  Journal of pharmaceutical sciences 20090701

• Flow-mediated dilation in patients with coronary artery disease is enhanced by high dose atorvastatin compared to combined low dose atorvastatin and ezetimibe: results of the CEZAR study.

  Atherosclerosis 20090701

• Niemann-Pick C1 Like 1 (NPC1L1) an intestinal sterol transporter.

  Biochimica et biophysica acta 20090701

• Effects of ezetimibe and simvastatin on apolipoprotein B metabolism in males with mixed hyperlipidemia.

  Journal of lipid research 20090701

• Ezetimibe and atorvastatin both immunoregulate CD4+ T cells from cardiac transplant recipients invitro.

  Transplant immunology 20090701

• The VYtorin on Carotid intima-media thickness and overall arterial rigidity (VYCTOR) study.

  Journal of clinical pharmacology 20090701

• Narrative review: statin-related myopathy.

  Annals of internal medicine 20090616

• Lipid-altering efficacy and safety of ezetimibe/simvastatin versus atorvastatin in patients with hypercholesterolemia and the metabolic syndrome (from the VYMET study).

  The American journal of cardiology 20090615

• The effects of ezetimibe on LDL-cholesterol: quantitative or qualitative changes?

  Atherosclerosis 20090601

• Ezetimibe treatment of pediatric patients with hypercholesterolemia.

  The Journal of pediatrics 20090601

• Disposition of flavonoids via enteric recycling: UDP-glucuronosyltransferase (UGT) 1As deficiency in Gunn rats is compensated by increases in UGT2Bs activities.

  The Journal of pharmacology and experimental therapeutics 20090601

• Fluvastatin/fenofibrate vs. simvastatin/ezetimibe in patients with metabolic syndrome: different effects on LDL-profiles.

  European journal of clinical investigation 20090601

• Effect on serum lipid levels of switching dose of ezetimibe from 10 to 5 mg.

  The American journal of cardiology 20090601

• Quantitative analysis of ezetimibe in human plasma by gas chromatography-mass spectrometry.

  Journal of separation science 20090601

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20090601

• Efficacy and safety of ezetimibe/simvastatin association on non-diabetic and diabetic patients with polygenic hypercholesterolemia or combined hyperlipidemia and previously intolerant to standard statin treatment.

  Journal of clinical pharmacy and therapeutics 20090601

• Drugs for children with hypercholesterolemia: be cautious.

  Journal of pediatric endocrinology & metabolism : JPEM 20090601

• Ezetimibe as monotherapy in the treatment of hypercholesterolemia in children and adolescents.

  Journal of pediatric endocrinology & metabolism : JPEM 20090601

• [Effectiveness of ezetimibe in improving lipid goal attainment in patients with coronary heart diseases treated with statin].

  Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20090601

• [Efficacy and safety of ezetimibe/simvastatin combination therapy in patients with type 2 diabetes and nonalcoholic fatty liver disease].

  Orvosi hetilap 20090524

• The impact of ezetimibe and high-dose of statin treatment on LDL levels in patients with heterozygous familial hypercholesterolemia.

  International journal of cardiology 20090515

• Ezetimibe monotherapy for cholesterol lowering in 2,722 people: systematic review and meta-analysis of randomized controlled trials.

  Journal of internal medicine 20090501

• Fact or fiction: the need for independent pharmaceutical policy research.

  Journal of general internal medicine 20090501

• Safety and effectiveness of ezetimibe in liver transplant recipients with hypercholesterolemia.

  Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20090501

• Utility of ezetimibe.

  The American journal of cardiology 20090501

• What role for [black triangle down] colesevelam in cardiovascular prevention?

  Drug and therapeutics bulletin 20090501

• [Effects of different statin regimens on lipid profile and serum metalloproteinases in patients with coronary heart disease].

  Zhonghua xin xue guan bing za zhi 20090501

• An assessment of the carcinogenic potential of ezetimibe using nonclinical data in a weight-of-evidence approach.

  Toxicology 20090428

• Vascular lipid accumulation, lipoprotein oxidation, and macrophage lipid uptake in hypercholesterolemic zebrafish.

  Circulation research 20090424

• 2-Azetidinone derivatives: design, synthesis and evaluation of cholesterol absorption inhibitors.

  European journal of medicinal chemistry 20090401

• Relationship of metabolic syndrome with incident aortic valve calcium and aortic valve calcium progression: the Multi-Ethnic Study of Atherosclerosis (MESA).

  Diabetes 20090401

• Increased persistency in medication use by U.S. Medicare beneficiaries with diabetes is associated with lower hospitalization rates and cost savings.

  Diabetes care 20090401

• Ezetimibe reduces plaque inflammation in a rabbit model of atherosclerosis and inhibits monocyte migration in addition to its lipid-lowering effect.

  British journal of pharmacology 20090401

• Lipid-altering efficacy of ezetimibe/simvastatin 10/20 mg compared with rosuvastatin 10 mg in high-risk hypercholesterolaemic patients inadequately controlled with prior statin monotherapy - The IN-CROSS study.

  International journal of clinical practice 20090401

• Statin and ezetimibe combination therapy in cardiovascular disease.

  Current opinion in endocrinology, diabetes, and obesity 20090401

• The g.-762T>C polymorphism of the NPC1L1 gene is common in Chinese and contributes to a higher promoter activity and higher serum cholesterol levels.

  Journal of human genetics 20090401

• Accelerated atherosclerosis in systemic lupus erythematosus: perspectives towards decreasing cardiovascular morbidity and mortality.

  Lupus 20090401

• Low-density lipoprotein cholesterol reduction and prevention of cardiovascular disease.

  Mayo Clinic proceedings 20090401

• Impact of ezetimibe on atherosclerosis: is the jury still out?

  Mayo Clinic proceedings 20090401

• Preparation and physicochemical characterization of surfactant based solid dispersions of ezetimibe.

  Die Pharmazie 20090401

• The Zetia challenge: an update.

  The Johns Hopkins medical letter health after 50 20090401

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20090401

• Low-flow aortic stenosis in asymptomatic patients: valvular-arterial impedance and systolic function from the SEAS Substudy.

  JACC. Cardiovascular imaging 20090401

• Aortic stenosis: look globally, think globally.

  JACC. Cardiovascular imaging 20090401

• Ezetimibe - new anti-atherogenic properties?

  British journal of pharmacology 20090401

• Both the peroxisome proliferator-activated receptor delta agonist, GW0742, and ezetimibe promote reverse cholesterol transport in mice by reducing intestinal reabsorption of HDL-derived cholesterol.

  Clinical and translational science 20090401

• Add-on therapy for hypercholesterolemia: a pilot comparison of two gastrointestinally-acting agents in statin-treated patients.

  Journal of clinical lipidology 20090401

• Ezetimibe, and the combination of ezetimibe/simvastatin, and risk of cancer: A post-marketing analysis.

  Journal of clinical lipidology 20090401

• The efficacy and tolerability of ezetimibe in cardiac transplant recipients taking cyclosporin.

  Transplantation 20090315

• Vascular protective effects of ezetimibe in ApoE-deficient mice.

  Atherosclerosis 20090301

• Novel genetic variants linked to coronary artery disease by genome-wide association are not associated with carotid artery intima-media thickness or intermediate risk phenotypes.

  Atherosclerosis 20090301

• Role of ezetimibe in the management of patients with atherosclerosis.

  Coronary artery disease 20090301

• Ezetimibe is an inhibitor of tumor angiogenesis.

  The American journal of pathology 20090301

• Lowering low-density lipoprotein cholesterol: statins, ezetimibe, bile acid sequestrants, and combinations: comparative efficacy and safety.

  Endocrinology and metabolism clinics of North America 20090301

• Statins reduce the neurofibrillary tangle burden in a mouse model of tauopathy.

  Journal of neuropathology and experimental neurology 20090301

• Simvastatin with or without ezetimibe in familial hypercholesterolemia (the ENHANCE trial).

  Current atherosclerosis reports 20090301

• Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis (the SEAS trial).

  Current atherosclerosis reports 20090301

• [semFYC and ezetimib].

  Atencion primaria 20090301

• The use of lipid-lowering drug therapy in children and adolescents.

  Current opinion in investigational drugs (London, England : 2000) 20090301

• ['The lower LDL cholesterol levels, the better' still valid. Negative/neutral conclusions of three studies on statins do not change the clinical practice].

  Lakartidningen 20090301

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20090301

• Ezetimibe lowers cholesterol levels.

  Project Inform perspective 20090301

• Amid lingering questions, FDA reprieves LDL cholesterol-lowering medication.

  JAMA 20090225

• The effect of exogenous cholesterol and lipid-modulating agents on enterocytic amyloid-beta abundance.

  The British journal of nutrition 20090201

• Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia.

  Journal of lipid research 20090201

• On the road to better dyslipidemia outcomes.

  The Nurse practitioner 20090201

• Controversial role of plant sterol esters in the management of hypercholesterolaemia.

  European heart journal 20090201

• Pooled analyses of effects on C-reactive protein and low density lipoprotein cholesterol in placebo-controlled trials of ezetimibe monotherapy or ezetimibe added to baseline statin therapy.

  The American journal of cardiology 20090201

• Perspectives on low-density lipoprotein cholesterol goal achievement.

  Current medical research and opinion 20090201

• Colesevelam hydrochloride: usefulness of a specifically engineered bile acid sequestrant for lowering LDL-cholesterol.

  European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20090201

• Ask the doctor. Can muscle damage from a statin, or from strenuous exercise, elevate creatinine even after I stopped taking the statin and exercising but continue to take Zetia and Diovan HCT?

  Harvard heart letter : from Harvard Medical School 20090201

• Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation.

  Circulation 20090106

• Asymmetric dimethylarginine and the effect of folate substitution in children with familial hypercholesterolemia and diabetes mellitus type 1.

  Physiological research 20090101

• Ezetimibe potently reduces vascular inflammation and arteriosclerosis in eNOS-deficient ApoE ko mice.

  Atherosclerosis 20090101

• The effect of statin alone or in combination with ezetimibe on postprandial lipoprotein composition in obese metabolic syndrome patients.

  Atherosclerosis 20090101

• Use of ezetimibe during HIV infection.

  The Journal of antimicrobial chemotherapy 20090101

• Is there evidence-based hypolipidemic treatment with clinical benefit beyond statins?

  Angiology 20090101

• After the failure of ENHANCEd cholesterol lowering in familial hypercholesterolemia, SEAS of problems with ezetimibe.

  Angiology 20090101

• Diabetes reduces bone marrow and circulating porcine endothelial progenitor cells, an effect ameliorated by atorvastatin and independent of cholesterol.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20090101

• Lack of pharmacokinetic interaction of mipomersen sodium (ISIS 301012), a 2'-O-methoxyethyl modified antisense oligonucleotide targeting apolipoprotein B-100 messenger RNA, with simvastatin and ezetimibe.

  Clinical pharmacokinetics 20090101

• Should we treat all primary prevention patients with statins?

  Current atherosclerosis reports 20090101

• A review of trials evaluating nonstatin lipid-lowering therapies.

  Current atherosclerosis reports 20090101

• Novel nonstatin strategies to lower low-density lipoprotein cholesterol.

  Current atherosclerosis reports 20090101

• Simvastatin with or without ezetimibe in familial hypercholesterolemia.

  Current atherosclerosis reports 20090101

• Effect of guggulsterone and cembranoids of Commiphora mukul on pancreatic phospholipase A(2): role in hypocholesterolemia.

  Journal of natural products 20090101

• Standards of medical care in diabetes--2009.

  Diabetes care 20090101

• Calcific aortic stenosis.

  The New England journal of medicine 20090101

• Analyses of cancer data from three ezetimibe trials.

  The New England journal of medicine 20090101

• No effect of lipid lowering on platelet activity in patients with coronary artery disease and type 2 diabetes or impaired glucose tolerance.

  Thrombosis and haemostasis 20090101

• [Orange skin and xanthomas associated with lycopenaemia in a setting of type III dyslipoproteinemia].

  Annales de dermatologie et de venereologie 20090101

• Lipid-lowering drugs acting at the level of the gastrointestinal tract.

  Current pharmaceutical design 20090101

• ACE inhibition attenuates uremia-induced aortic valve thickening in a novel mouse model.

  BMC cardiovascular disorders 20090101

• Efficacy and safety of coadministration of fenofibrate and ezetimibe compared with each as monotherapy in patients with type IIb dyslipidemia and features of the metabolic syndrome: a prospective, randomized, double-blind, three-parallel arm, multicenter, comparative study.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20090101

• Obesity, the endocannabinoid system, and bias arising from pharmaceutical sponsorship.

  PloS one 20090101

• Medicinal treatments of cholesterol gallstones: old, current and new perspectives.

  Current medicinal chemistry 20090101

• Cardiovascular magnetic resonance parameters of atherosclerotic plaque burden improve discrimination of prior major adverse cardiovascular events.

  Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20090101

• Impact of ezetimibe on cholesterol subfractions in dyslipidemic cardiac transplant recipients receiving statin therapy.

  Clinical transplantation 20090101

• Efficacy and safety of rosuvastatin in the management of dyslipidemia.

  Vascular health and risk management 20090101

• Management of complex lipid abnormalities with a fixed dose combination of simvastatin and extended release niacin.

  Vascular health and risk management 20090101

• The effect of angiotensin receptor blockers on C-reactive protein and other circulating inflammatory indices in man.

  Vascular health and risk management 20090101

• Effects of simvastatin 40 mg daily on muscle and liver adverse effects in a 5-year randomized placebo-controlled trial in 20,536 high-risk people.

  BMC clinical pharmacology 20090101

• The role of pH in the glucuronidation of raloxifene, mycophenolic acid and ezetimibe.

  Molecular pharmaceutics 20090101

• Dyslipidemia treatment of patients with diabetes mellitus in a US managed care plan: a retrospective database analysis.

  Cardiovascular diabetology 20090101

• Mechanism of inhibitory effect of atorvastatin on resistin expression induced by tumor necrosis factor-alpha in macrophages.

  Journal of biomedical science 20090101

• Efficacy, effectiveness and real life goal attainment of statins in managing cardiovascular risk.

  Vascular health and risk management 20090101

• Coronary heart disease and dyslipidemia: a cross-sectional evaluation of prevalence, current treatment, and clinical control in a large cohort of Spanish high-risk patients: the PRINCEPS study.

  Preventive cardiology 20090101

• LDL-Cholesterol is the King.

  Angiology 20090101

• Kidney function and estimated vascular risk in patients with primary dyslipidemia.

  The open cardiovascular medicine journal 20090101

• Lipoproteins, cholesterol homeostasis and cardiac health.

  International journal of biological sciences 20090101

• Regulation of bile acid and cholesterol metabolism by PPARs.

  PPAR research 20090101

• Translocation of bacterial NOD2 agonist and its link with inflammation.

  Critical care (London, England) 20090101

• Protonated nanostructured aluminosilicate (NSAS) reduces plasma cholesterol concentrations and atherosclerotic lesions in Apolipoprotein E deficient mice fed a high cholesterol and high fat diet.

  Lipids in health and disease 20090101

• New options in the treatment of lipid disorders in HIV-infected patients.

  The open AIDS journal 20090101

• Characteristics, management and attainment of lipid target levels in diabetic and cardiac patients enrolled in Disease Management Program versus those in routine care: LUTZ registry.

  BMC public health 20090101

• Safety of the combination of intensive cholesterol-lowering therapy with oral anticoagulation medication in elderly patients with atrial fibrillation: a randomized, double-blind, placebo-controlled study.

  Drugs & aging 20090101

• Disappointing recent cholesterol-lowering drug trials: is it not time for a full reappraisal of the cholesterol theory?

  World review of nutrition and dietetics 20090101

• Low and high density lipoprotein--cholesterol and coronary atherothrombosis.

  Medicinski pregled 20090101

• Cardiovascular disease in patients with chronic kidney disease.

  Vascular health and risk management 20090101

• Statins and ezetimibe modulate plasma proprotein convertase subtilisin kexin-9 (PCSK9) levels.

  Transactions of the American Clinical and Climatological Association 20090101

• Drugs associated with more suicidal ideations are also associated with more suicide attempts.

  PloS one 20090101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20090101

• Effects of ezetimibe add-on therapy for high-risk patients with dyslipidemia.

  Lipids in health and disease 20090101

• Vancomycin-induced thrombocytopenia in a 60-year-old man: a case report.

  Journal of medical case reports 20090101

• Triple X syndrome in a patient with partial lipodystrophy discovered using a high-density oligonucleotide microarray: a case report.

  Journal of medical case reports 20090101

• Rosuvastatin increased serum osteocalcin levels independent of its serum cholesterol-lowering effect in patients with type 2 diabetes and hypercholesterolemia.

  Internal medicine (Tokyo, Japan) 20090101

• Pleiotropic vasoprotective effects of statins: the chicken or the egg?

  Drug design, development and therapy 20090101

• Hypercholesterolemia and myocardial function evaluated via tissue doppler imaging.

  Cardiovascular ultrasound 20090101

• Loss of PDZK1 causes coronary artery occlusion and myocardial infarction in Paigen diet-fed apolipoprotein E deficient mice.

  PloS one 20090101

• Management of dyslipidemia in children.

  Diabetology & metabolic syndrome 20090101

• Fecal bile acid excretion and messenger RNA expression levels of ileal transporters in high risk gallstone patients.

  Lipids in health and disease 20090101

• Critical appraisal of the role of pitavastatin in treating dyslipidemias and achieving lipid goals.

  Vascular health and risk management 20090101

• Vascular health in children and adolescents: effects of obesity and diabetes.

  Vascular health and risk management 20090101

• [Achievement of blood lipid target levels with Ezetimibe/Simvastatin in patients with atherosclerosis and/or diabetes mellitus--an Austrian observational study].

  Wiener medizinische Wochenschrift (1946) 20090101

• Review of extended-release niacin/laropiprant fixed combination in the treatment of mixed dyslipidemia and primary hypercholesterolemia.

  Vascular health and risk management 20090101

• Comparison of the efficacy of administering a combination of ezetimibe plus fenofibrate versus atorvastatin monotherapy in the treatment of dyslipidemia.

  Lipids in health and disease 20090101

• Model system for the analysis of cell surface expression of human ABCA1.

  BMC cell biology 20090101

• The JUPITER and AURORA clinical trials for rosuvastatin in special primary prevention populations: perspectives, outcomes, and consequences.

  Vascular health and risk management 20090101

• Management of asymptomatic severe aortic stenosis.

  Current cardiology reviews 20090101

• A comparative evaluation of safety and efficacy of rosuvastatin, simvastatin, and atorvastatin in patients of type 2 diabetes mellitus with dyslipidemia.

  International journal of diabetes in developing countries 20090101

• Recent advances in medical treatment and percutaneous, transapical and surgical interventions in aortic-valve stenosis.

  F1000 medicine reports 20090101

• Improving glycemic and cholesterol control through an integrated approach incorporating colesevelam - a clinical perspective.

  Diabetes, metabolic syndrome and obesity : targets and therapy 20090101

• A review of the current status of the management of mixed dyslipidemia associated with diabetes mellitus and metabolic syndrome.

  The American journal of cardiology 20081222

• Effect of statins alone versus statins plus ezetimibe on carotid atherosclerosis in type 2 diabetes: the SANDS (Stop Atherosclerosis in Native Diabetics Study) trial.

  Journal of the American College of Cardiology 20081216

• Additional lipid lowering trials using surrogate measurements of atherosclerosis by carotid intima-media thickness: more clarity or confusion?

  Journal of the American College of Cardiology 20081216

• Lipid-lowering therapy does not affect the postprandial drop in high density lipoprotein-cholesterol (HDL-c) plasma levels in obese men with metabolic syndrome: a randomized double blind crossover trial.

  Clinical endocrinology 20081201

• VAP II analysis of lipoprotein subclasses in mixed hyperlipidemic patients on treatment with ezetimibe/simvastatin and fenofibrate.

  Journal of lipid research 20081201

• Origins of intestinal ABCA1-mediated HDL-cholesterol.

  Journal of lipid research 20081201

• Formulation and in vivo evaluation of self-nanoemulsifying granules for oral delivery of a combination of ezetimibe and simvastatin.

  Drug development and industrial pharmacy 20081201

• Is there a problem with ezetimibe or just ENHANCEd hype?

  Angiology 20081201

• Effect of ezetimibe on plasma cholesterol levels, cholesterol absorption, and secretion of biliary cholesterol in laboratory opossums with high and low responses to dietary cholesterol.

  Metabolism: clinical and experimental 20081201

• Efficacy and safety of ezetimibe added on to atorvastatin (20 mg) versus uptitration of atorvastatin (to 40 mg) in hypercholesterolemic patients at moderately high risk for coronary heart disease.

  The American journal of cardiology 20081201

• Efficacy and safety of ezetimibe added on to atorvastatin (40 mg) compared with uptitration of atorvastatin (to 80 mg) in hypercholesterolemic patients at high risk of coronary heart disease.

  The American journal of cardiology 20081201

• Intensive lipid-lowering therapy for patients with aortic stenosis.

  The American journal of cardiology 20081201

• The effects of ezetimibe and orlistat, alone or in combination, on high-density lipoprotein (HDL) subclasses and HDL-associated enzyme activities in overweight and obese patients with hyperlipidaemia.

  Expert opinion on pharmacotherapy 20081201

• Ezetimibe in the treatment of uncontrolled hyperlipidemia in kidney transplant patients.

  Transplantation proceedings 20081201

• The top 10 health stories of 2008.

  Harvard health letter 20081201

• Tolerability and effects on lipids of ezetimibe coadministered with pravastatin or simvastatin for twelve months: results from two open-label extension studies in hypercholesterolemic patients.

  Clinical therapeutics 20081201

• SREBP-2 regulates gut peptide secretion through intestinal bitter taste receptor signaling in mice.

  The Journal of clinical investigation 20081103

• Endothelial progenitor cell levels in obese men with the metabolic syndrome and the effect of simvastatin monotherapy vs. simvastatin/ezetimibe combination therapy.

  European heart journal 20081101

• Reductions in all-cause, cancer, and coronary mortality in statin-treated patients with heterozygous familial hypercholesterolaemia: a prospective registry study.

  European heart journal 20081101

• Long-term safety and tolerability of ezetimibe coadministered with simvastatin in hypercholesterolemic patients: a randomized, 12-month double-blind extension study.

  Current medical research and opinion 20081101

• Effectiveness of thrice weekly ezetimibe.

  The American journal of cardiology 20081101

• LDL reduction: how low should we go and is it safe?

  Current cardiology reports 20081101

• American College of Endocrinology Pre-Diabetes Consensus Conference: part two.

  Diabetes care 20081101

• Is carotid intima-media thickness a reliable clinical predictor?

  Mayo Clinic proceedings 20081101

• Informed consent and shared decision-making: a requirement to disclose to patients off-label prescriptions.

  PLoS medicine 20081101

• Treatment with ezetimibe in kidney transplant recipients with uncontrolled dyslipidemia.

  Transplantation proceedings 20081101

• Safety and efficacy of ezetimibe in a sample of cardiac transplant patients.

  Transplantation proceedings 20081101

• The efficacy and safety of ezetimibe for treatment of dyslipidemia after heart transplantation.

  Transplantation proceedings 20081101

• Uncertainty dogs Zetia and Vytorin.

  Harvard heart letter : from Harvard Medical School 20081101

• Rationale and design of IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial): comparison of ezetimbe/simvastatin versus simvastatin monotherapy on cardiovascular outcomes in patients with acute coronary syndromes.

  American heart journal 20081101

• The ENHANCE trial.

  Cleveland Clinic journal of medicine 20081101

• The ENHANCE trial.

  Cleveland Clinic journal of medicine 20081101

• Efficacy and safety of coadministration of ezetimibe and simvastatin in adolescents with heterozygous familial hypercholesterolemia.

  Journal of the American College of Cardiology 20081021

• Ezetimibe alone reduces low-density lipoprotein cholesterol in HIV-infected patients receiving combination antiretroviral therapy.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20081015

• Self-nanoemulsifying granules of ezetimibe: design, optimization and evaluation.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20081002

• Quantitative 3T MR imaging of the descending thoracic aorta: patients with familial hypercholesterolemia have an increased aortic plaque burden despite long-term lipid-lowering therapy.

  Journal of vascular and interventional radiology : JVIR 20081001

• Inhibiting intestinal NPC1L1 activity prevents diet-induced increase in biliary cholesterol in Golden Syrian hamsters.

  American journal of physiology. Gastrointestinal and liver physiology 20081001

• Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1l1-/- mice.

  American journal of physiology. Gastrointestinal and liver physiology 20081001

• Sustained effects in hypercholesterolaemic patients on combined simvastatin/ezetimibe treatment: observational cohort study in clinical practice.

  Current medical research and opinion 20081001

• Ptosis, diplopia and statins: an association?

  European journal of neurology 20081001

• [Therapy of familial hypercholesterolemia with or without ezetimibe].

  Der Internist 20081001

• Therapy and clinical trials.

  Current opinion in lipidology 20081001

• Long-term (48-week) safety of ezetimibe 10 mg/day coadministered with simvastatin compared to simvastatin alone in patients with primary hypercholesterolemia.

  Current medical research and opinion 20081001

• Left ventricular systolic and diastolic function in asymptomatic patients with moderate aortic stenosis.

  The American journal of cardiology 20081001

• American College Of Endocrinology Pre-Diabetes Consensus Conference: part one.

  Diabetes care 20081001

• Muddy waters: more stormy SEAS for ezetimibe.

  International journal of clinical practice 20081001

• Long-term efficacy and safety of ezetimibe 10 mg in patients with homozygous sitosterolemia: a 2-year, open-label extension study.

  International journal of clinical practice 20081001

• Ezetimibe 5 and 10 mg for lowering LDL-C: potential billion-dollar savings with improved tolerability.

  The American journal of managed care 20081001

• On call. I don't understand the problem with Vytorin. The two components when used separately work fine, but when mixed together things change. Why?

  Harvard men's health watch 20081001

• Renal failure and rhabdomyolysis associated with sitagliptin and simvastatin use.

  Diabetic medicine : a journal of the British Diabetic Association 20081001

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20081001

• Update on the clinical utility of fenofibrate in mixed dyslipidemias: mechanisms of action and rational prescribing.

  Vascular health and risk management 20081001

• A Commentary on the implications of the ENHANCE (Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression) Trial: Should ezetimibe move to the 'Back of the Line' as a therapy for dyslipidemia?

  Journal of clinical lipidology 20081001

• Ezetimibe-related myopathy: A systematic review.

  Journal of clinical lipidology 20081001

• Optimal management of lipids in diabetes and metabolic syndrome.

  Journal of clinical lipidology 20081001

• Neuropharmacology.

  Indian journal of pharmacology 20081001

• Analyses of cancer data from three ezetimibe trials.

  The New England journal of medicine 20080925

• Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis.

  The New England journal of medicine 20080925

• Ezetimibe and cancer--an uncertain association.

  The New England journal of medicine 20080925

• Identifying and addressing safety signals in clinical trials.

  The New England journal of medicine 20080925

• Hypercholesterolaemia: Clarifications from adverse drug reactions agency.

  BMJ (Clinical research ed.) 20080916

• After ENHANCE: the cholesterol hypothesis is alive and well.

  The Medical journal of Australia 20080915

• [Ezetimibe=cost effectiveness. Science or a debate contribution from MSD?].

  Ugeskrift for laeger 20080915

• [The evidence of clinical effects of ezetimibe is not sufficient].

  Ugeskrift for laeger 20080915

• Reasons to be cautious about cholesterol lowering drugs.

  BMJ (Clinical research ed.) 20080903

• Safety and efficacy of ezetimibe monotherapy in 1624 primary hypercholesterolaemic patients for up to 2 years.

  International journal of clinical practice 20080901

• Cholesterol homeostasis by the intestine: lessons from Niemann-Pick C1 Like 1 [NPC1L1).

  Atherosclerosis. Supplements 20080901

• CD8+ cutaneous T-cell lymphoma successfully treated with bexarotene: a case report and review of the literature.

  American journal of hematology 20080901

• Statin plus ezetimibe treatment in clinical practice: the SI-SPECT (Slovenia (SI) Statin Plus Ezetimibe in Cholesterol Treatment) monitoring of clinical practice study.

  Current medical research and opinion 20080901

• The development of novel anti-hyperlipidemic drugs: a tough business gets tougher.

  Current opinion in investigational drugs (London, England : 2000) 20080901

• Simvastatin-ezetimibe-induced hepatic failure necessitating liver transplantation.

  Pharmacotherapy 20080901

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20080901

• Does 'ENHANCE' diminish confidence in ezetimibe?

  The Journal of the Association of Physicians of India 20080901

• Preliminary observations from preliminary trial results: have we finally had enough?

  Circulation. Cardiovascular quality and outcomes 20080901

• Serious drug-induced liver disease secondary to ezetimibe.

  World journal of gastroenterology 20080828

• Ezetimibe revisited.

  The Medical letter on drugs and therapeutics 20080825

• Stages of motor output reorganization after hemispheric stroke suggested by longitudinal studies of cortical physiology.

  Cerebral cortex (New York, N.Y. : 1991) 20080801

• Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia.

  Nature clinical practice. Cardiovascular medicine 20080801

• Effects of statins on high-density lipoproteins: a potential contribution to cardiovascular benefit.

  Cardiovascular drugs and therapy 20080801

• Subclinical atherosclerosis: what it is, what it means and what we can do about it.

  International journal of clinical practice 20080801

• Effects of ezetimibe, either alone or in combination with atorvastatin, on serum visfatin levels: a pilot study.

  Expert opinion on pharmacotherapy 20080801

• Enhanced hype.

  The American journal of cardiology 20080801

• Beneficial effects of ezetimibe-based therapy in patients with dyslipidemia.

  Journal of cardiology 20080801

• The effects of low-dose simvastatin and ezetimibe compared to high-dose simvastatin alone on post-fat load endothelial function in patients with metabolic syndrome: a randomized double-blind crossover trial.

  Journal of cardiovascular pharmacology 20080801

• Intensive lipid intervention in the post-ENHANCE era.

  Mayo Clinic proceedings 20080801

• Cardiovascular prevention (VI). Use of drugs in the primary prevention of arterial hypertension and dyslipidemia.

  Revista espanola de cardiologia 20080801

• A novel approach for prevention and dissolution of cholesterol gallstones.

  Liver international : official journal of the International Association for the Study of the Liver 20080801

• Ezetimibe prevents cholesterol gallstone formation in mice.

  Liver international : official journal of the International Association for the Study of the Liver 20080801

• Estimating the health benefits and costs associated with ezetimibe coadministered with statin therapy compared with higher dose statin monotherapy in patients with established cardiovascular disease: results of a Markov model for UK costs using data registries.

  Clinical therapeutics 20080801

• The Relationship Between HIV Infection and Cardiovascular Disease.

  Current cardiology reviews 20080801

• Simvastatin with or without ezetimibe in familial hypercholesterolemia.

  The New England journal of medicine 20080731

• Simvastatin with or without ezetimibe in familial hypercholesterolemia.

  The New England journal of medicine 20080731

• Simvastatin with or without ezetimibe in familial hypercholesterolemia.

  The New England journal of medicine 20080731

• Simvastatin with or without ezetimibe in familial hypercholesterolemia.

  The New England journal of medicine 20080731

• Simvastatin with or without ezetimibe in familial hypercholesterolemia.

  The New England journal of medicine 20080731

• Simvastatin with or without ezetimibe in familial hypercholesterolemia.

  The New England journal of medicine 20080731

• Simvastatin with or without ezetimibe in familial hypercholesterolemia.

  The New England journal of medicine 20080731

• Functional characterization of genetic variants in NPC1L1 supports the sequencing extremes strategy to identify complex trait genes.

  Human molecular genetics 20080715

• [Effectiveness of cardiometabolic risk reduction in patients with type 1 diabetes mellitus].

  Orvosi hetilap 20080706

• [Crosstalk between cholesterol homeostasis and drug metabolism].

  Orvosi hetilap 20080706

• Niemann-pick C1-like 1 mediates alpha-tocopherol transport.

  Molecular pharmacology 20080701

• Cholesterol absorption from the intestine is a major determinant of reverse cholesterol transport from peripheral tissue macrophages.

  Arteriosclerosis, thrombosis, and vascular biology 20080701

• Cholesterol lowering is more important than pleiotropic effects of statins for endothelial function in patients with dysglycaemia and coronary artery disease.

  European heart journal 20080701

• Efficacy and safety of ezetimibe 40 mg vs. ezetimibe 10 mg in the treatment of patients with homozygous sitosterolaemia.

  International journal of clinical practice 20080701

• The effect of orlistat and ezetimibe, alone or in combination, on serum LDL and small dense LDL cholesterol levels in overweight and obese patients with hypercholesterolaemia.

  Current medical research and opinion 20080701

• Effect of ezetimibe coadministration with simvastatin in a Middle Eastern population: a prospective, multicentre, randomized, double-blind, placebo-controlled trial.

  Journal of cardiovascular medicine (Hagerstown, Md.) 20080701

• Disposition of ezetimibe is influenced by polymorphisms of the hepatic uptake carrier OATP1B1.

  Pharmacogenetics and genomics 20080701

• Is it over for ezetimibe?

  Expert review of cardiovascular therapy 20080701

• Highlights from the 57th annual scientific session of the American College of Cardiology.

  The Journal of thoracic and cardiovascular surgery 20080701

• A drug, a concept, and a clinical trial on trial.

  Cleveland Clinic journal of medicine 20080701

• Is ezetimibe/simvastatin no better than simvastatin alone? Lessons learned and clinical implications.

  Cleveland Clinic journal of medicine 20080701

• Given the ENHANCE trial results, ezetimibe is still unproven.

  Cleveland Clinic journal of medicine 20080701

• Rhabdomyolysis resulting from pharmacologic interaction between erlotinib and simvastatin.

  Clinical lung cancer 20080701

• Rhabdomyolysis and pancreatitis associated with coadministration of danazol 600 mg/d and lovastatin 40 mg/d.

  Clinical therapeutics 20080701

• Simvastatin and ezetimibe in addition to nonpharmacological risk factor modification for achieving new low-density lipoprotein cholesterol targets.

  Herz 20080701

• [Cost effectiveness in the Danish health care of ezetemibe co-administration compared to simvastatin].

  Ugeskrift for laeger 20080623

• The ENHANCE study and marketing ezetimibe.

  JAMA 20080618

• Efficacy of rosuvastatin (5 mg and 10 mg) twice a week in patients intolerant to daily statins.

  The American journal of cardiology 20080615

• Selective binding of sterol regulatory element-binding protein isoforms and co-regulatory proteins to promoters for lipid metabolic genes in liver.

  The Journal of biological chemistry 20080606

• [Stable coronary heart disease--lessons from the COURAGE Study. With intensive drug therapy on the success track].

  MMW Fortschritte der Medizin 20080605

• [Dual cholesterol inhibition. More high risk patients achieve LDL cholesterol values below 100 mg/dl].

  MMW Fortschritte der Medizin 20080605

• After ENHANCE: is more LDL cholesterol lowering even better?

  Clinical chemistry 20080601

• Effect of ezetimibe on the prevention and dissolution of cholesterol gallstones.

  Gastroenterology 20080601

• Predictors of uncontrolled hyperlipidaemia in high-risk ambulatory patients in primary care.

  Current medical research and opinion 20080601

• The structure and function of Niemann-Pick C1-like 1 protein.

  Current opinion in lipidology 20080601

• Severe jaundice following treatment with ezetimibe.

  European journal of gastroenterology & hepatology 20080601

• Review of side-effect profile of combination ezetimibe and statin therapy in randomized clinical trials.

  The American journal of cardiology 20080601

• Effects of fenofibrate and ezetimibe, both as monotherapy and in coadministration, on cholesterol mass within lipoprotein subfractions and low-density lipoprotein peak particle size in patients with mixed hyperlipidemia.

  Metabolism: clinical and experimental 20080601

• Safety and efficacy of ezetimibe with low doses of simvastatin in heart transplant recipients.

  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080601

• Ezetimibe blocks internalization of the NPC1L1/cholesterol complex.

  Cell metabolism 20080601

• The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1.

  Cell metabolism 20080601

• Toward 'pain-free' statin prescribing: clinical algorithm for diagnosis and management of myalgia.

  Mayo Clinic proceedings 20080601

• Emerging antidyslipidemic drugs.

  Expert opinion on emerging drugs 20080601

• The implications of the ezetimibe and simvastatin in hypercholesterolemia enhances atherosclerosis regression trial: a return to first principles.

  Clinical cardiology 20080601

• [Lower is better: ENHANCE affair].

  Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 20080601

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20080601

• Elevated atherogenic lipoproteins in childhood: Risk, prevention, and treatment.

  Journal of clinical lipidology 20080601

• Pediatric dyslipidemias: Prescription medication efficacy and safety.

  Journal of clinical lipidology 20080601

• Cholesterol drug controversy continues.

  JAMA 20080521

• Effects of ezetimibe and/or simvastatin on LDL receptor protein expression and on LDL receptor and HMG-CoA reductase gene expression: a randomized trial in healthy men.

  Atherosclerosis 20080501

• Inhibition of intestinal absorption of cholesterol by ezetimibe or bile acids by SC-435 alters lipoprotein metabolism and extends the lifespan of SR-BI/apoE double knockout mice.

  Atherosclerosis 20080501

• SREBP-1c gene polymorphism is associated with increased inhibition of cholesterol-absorption in response to ezetimibe treatment.

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20080501

• HNF4alpha is a crucial modulator of the cholesterol-dependent regulation of NPC1L1.

  Pharmaceutical research 20080501

• Ezetimibe's effect on platelet aggregation and LDL tendency to peroxidation in hypercholesterolaemia as monotherapy or in addition to simvastatin.

  British journal of clinical pharmacology 20080501

• Ezetimibe for the treatment of primary (heterozygous-familial and non-familial) hypercholesterolaemia: NICE technology appraisal guidance.

  Heart (British Cardiac Society) 20080501

• Commentary on NICE technology appraisal guidance on ezetimibe for the treatment of primary (heterozygous-familial and non-familial) hypercholesterolaemia.

  Heart (British Cardiac Society) 20080501

• ENHANCE: food for the ostriches.

  International journal of clinical practice 20080501

• The ENHANCE Study: an unusual publication of trial data raises questions beyond ezetimibe.

  Expert opinion on pharmacotherapy 20080501

• Switching statin therapy using a pharmacist-managed therapeutic conversion program versus usual care conversion among indigent patients.

  Pharmacotherapy 20080501

• The effect of famotidine, esomeprazole, and ezetimibe on levothyroxine absorption.

  Thyroid : official journal of the American Thyroid Association 20080501

• Ezetimibe for the treatment of hypercholesterolaemia: a systematic review and economic evaluation.

  Health technology assessment (Winchester, England) 20080501

• ENHANCE and ACCORD: controversy over surrogate end points.

  Current cardiology reports 20080501

• Achieving target cholesterol levels in diabetic patients: potency of the statin or potency of the physician?

  The Israel Medical Association journal : IMAJ 20080501

• [Commentary to the article: Kastelein JJ, Akdim F, Stroes ES, et al.; ENHANCE Investigators. Simvastatin with or without ezetimibe in familial hypercholesterolemia. N Engl J Med 2008; 358: 1431-43 ].

  Kardiologia polska 20080501

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20080501

• Effectiveness of lipid-lowering therapy in HIV patients.

  Current opinion in HIV and AIDS 20080501

• American college of cardiology 57th scientific sessions, 2008.

  P & T : a peer-reviewed journal for formulary management 20080501

• Use of ezetimibe in the United States and Canada.

  The New England journal of medicine 20080424

• Vascular effects of diet supplementation with plant sterols.

  Journal of the American College of Cardiology 20080422

• Lipid-altering efficacy and safety of ezetimibe/simvastatin coadministered with extended-release niacin in patients with type IIa or type IIb hyperlipidemia.

  Journal of the American College of Cardiology 20080422

• [Dual lipid control without anti-atherosclerosis effect].

  MMW Fortschritte der Medizin 20080417

• Ezetimibe improves high fat and cholesterol diet-induced non-alcoholic fatty liver disease in mice.

  European journal of pharmacology 20080414

• Simvastatin with or without ezetimibe in familial hypercholesterolemia.

  The New England journal of medicine 20080403

• Cholesterol lowering and ezetimibe.

  The New England journal of medicine 20080403

• Does ENHANCE diminish confidence in lowering LDL or in ezetimibe?

  The New England journal of medicine 20080403

• Mismanaged measures.

  Nature 20080403

• Short-term treatment with ezetimibe, simvastatin or their combination does not alter circulating adiponectin, resistin or leptin levels in healthy men.

  Clinical endocrinology 20080401

• Madin-Darby canine kidney II cells: a pharmacologically validated system for NPC1L1-mediated cholesterol uptake.

  Molecular pharmacology 20080401

• Lipid-altering efficacy of ezetimibe/simvastatin 10/40 mg compared with doubling the statin dose in patients admitted to the hospital for a recent coronary event: the INFORCE study.

  International journal of clinical practice 20080401

• Development and physiological regulation of intestinal lipid absorption. III. Intestinal transporters and cholesterol absorption.

  American journal of physiology. Gastrointestinal and liver physiology 20080401

• Colesevelam hydrochloride in clinical practice: a new approach in the treatment of hypercholesterolaemia.

  Current medical research and opinion 20080401

• Activation of liver X receptor sensitizes mice to gallbladder cholesterol crystallization.

  Hepatology (Baltimore, Md.) 20080401

• Enhanced LDL-C reduction: lower is better. Does it matter how?

  International journal of clinical practice 20080401

• Relative atherogenicity and predictive value of non-high-density lipoprotein cholesterol for coronary heart disease.

  The American journal of cardiology 20080401

• Left atrial volume in patients with asymptomatic aortic valve stenosis (the Simvastatin and Ezetimibe in Aortic Stenosis study).

  The American journal of cardiology 20080401

• Lipid-lowering study raises issues of therapy's value.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080401

• Dramatically increased intestinal absorption of cholesterol following hypophysectomy is normalized by thyroid hormone.

  Gastroenterology 20080401

• Ezetimibe: cholesterol lowering and beyond.

  Expert review of cardiovascular therapy 20080401

• Development and validation of a stability-indicating micellar electrokinetic chromatography method for the determination of ezetimibe in pharmaceutical formulations.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20080401

• [Cost-effectiveness of managing familial hypercholesterolemia using atorvastatin-based preventive therapy].

  Revista espanola de cardiologia 20080401

• Combination therapy in cholesterol reduction: focus on ezetimibe and statins.

  Vascular health and risk management 20080401

• Clinical efficacy and safety of statins in managing cardiovascular risk.

  Vascular health and risk management 20080401

• Recent news reports suggest that the cholesterol medicine Zetia doesn't work. Should I stop taking my prescription?

  The Johns Hopkins medical letter health after 50 20080401

• Surrogate end points and FDA approval: a tale of 2 lipid-altering drugs.

  JAMA 20080326

• Plant sterols cause macrothrombocytopenia in a mouse model of sitosterolemia.

  The Journal of biological chemistry 20080307

• The efficacy of statin monotherapy uptitration versus switching to ezetimibe/simvastatin: results of the EASEGO study.

  Current medical research and opinion 20080301

• Ezetimibe-associated immune thrombocytopenia.

  The Annals of pharmacotherapy 20080301

• Pretreatment with high-dose statin, but not low-dose statin, ezetimibe, or the combination of low-dose statin and ezetimibe, limits infarct size in the rat.

  Journal of cardiovascular pharmacology and therapeutics 20080301

• An evaluation of rosuvastatin: pharmacokinetics, clinical efficacy and tolerability.

  Expert opinion on drug metabolism & toxicology 20080301

• Rx for uncertainty. Does a popular cholesterol-lowering drug do what it's supposed to do?

  Diabetes forecast 20080301

• Controversies surround heart drug study: questions about Vytorin and trial sponsors' conduct.

  JAMA 20080227

• Critical lessons from the ENHANCE trial.

  JAMA 20080227

• Effectiveness of ezetimibe alone or in combination with twice a week Atorvastatin (10 mg) for statin intolerant high-risk patients.

  The American journal of cardiology 20080215

• Efficacy and tolerability of fluvastatin XL 80 mg alone, ezetimibe alone, and the combination of fluvastatin XL 80 mg with ezetimibe in patients with a history of muscle-related side effects with other statins.

  The American journal of cardiology 20080215

• Factors influencing left ventricular structure and stress-corrected systolic function in men and women with asymptomatic aortic valve stenosis (a SEAS Substudy).

  The American journal of cardiology 20080215

• Targets for intervention in dyslipidemia in diabetes.

  Diabetes care 20080201

• Update on the use of fibrates: focus on bezafibrate.

  Vascular health and risk management 20080201

• High density lipoprotein cholesterol: an evolving target of therapy in the management of cardiovascular disease.

  Vascular health and risk management 20080201

• In brief: Zetia and Vytorin: the ENHANCE study.

  The Medical letter on drugs and therapeutics 20080128

• Unreported cholesterol drug data released by company.

  BMJ (Clinical research ed.) 20080126

• Substituted oxazolidinones as novel NPC1L1 ligands for the inhibition of cholesterol absorption.

  Bioorganic & medicinal chemistry letters 20080115

• Ezetimibe treatment in hypercholesterolemic kidney transplant patients is safe and effective and reduces the decline of renal allograft function: a pilot study.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080101

• Effects of ezetimibe, simvastatin, atorvastatin, and ezetimibe-statin therapies on non-cholesterol sterols in patients with primary hypercholesterolemia.

  Current medical research and opinion 20080101

• Ezetimibe plus simvastatin cardiovascular outcomes study program.

  Expert review of cardiovascular therapy 20080101

• Human cholesterol metabolism and therapeutic molecules.

  Experimental physiology 20080101

• Ezetimibe-associated adverse effects: what the clinician needs to know.

  International journal of clinical practice 20080101

• Optimal management of combined dyslipidemia: what have we behind statins monotherapy?

  Advances in cardiology 20080101

• Lipid profiles of patients with a transplanted heart before and after the operation.

  Transplantation proceedings 20080101

• Lipid-lowering therapy in patients with type 2 diabetes: the case for early intervention.

  Diabetes/metabolism research and reviews 20080101

• Should We Use PPAR Agonists to Reduce Cardiovascular Risk?

  PPAR research 20080101

• Effects of fluvastatin extended-release (80 mg) alone and in combination with ezetimibe (10 mg) on low-density lipoprotein cholesterol and inflammatory parameters in patients with primary hypercholesterolemia: a 12-week, multicenter, randomized, open-label, parallel-group study.

  Clinical therapeutics 20080101

• The Lipid lowering and Onset of Renal Disease (LORD) Trial: a randomized double blind placebo controlled trial assessing the effect of atorvastatin on the progression of kidney disease.

  BMC nephrology 20080101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20080101

• Is Zetia a 'do nothing' drug?

  Current topics in medicinal chemistry 20080101

• Fibrate therapy: an update.

  Cardiology in review 20080101

• Ezetimibe effectively lowers LDL-cholesterol in cardiac allograft recipients on stable statin therapy.

  Clinical transplantation 20080101

• The cholesterol hypothesis: questioned?

  American journal of therapeutics 20080101

• Making sense of ENHANCE: ezetimibe (Zetia) lowers LDL cholesterol but doesn't decrease carotid intima-media thickness.

  The Mount Sinai journal of medicine, New York 20080101

• [A new approach to the treatment of dyslipidemia].

  Medicina (Kaunas, Lithuania) 20080101

• Effect of dietary fat on hepatic liver X receptor expression in P-glycoprotein deficient mice: implications for cholesterol metabolism.

  Lipids in health and disease 20080101

• ENHANCE results: a surrogate trial that impacts beyond size and scope.

  Cardiovascular journal of Africa 20080101

• Ezetimibe, a selective inhibitor of the transport of cholesterol.

  Internal medicine (Tokyo, Japan) 20080101

• Carotid intima-media thickness (cIMT): a useful clinic tool or research luxury? Another view of the ENHANCE trial.

  Angiology 20080101

• Combination drug products: an indication for medication reconciliation and pharmacist counseling.

  Journal of the American Pharmacists Association : JAPhA 20080101

• Acute myocardial infarction in an 18 year old South Indian girl with familial hypercholesterolemia: a case report.

  Cases journal 20080101

• Current and future pharmacologic options for the management of patients unable to achieve low-density lipoprotein-cholesterol goals with statins.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20080101

• Monitoring therapeutical intervention with ezetimibe using targeted near-infrared fluorescence imaging in experimental atherosclerosis.

  Molecular imaging 20080101

• [Cardiovascular mortality in kidney transplatation].

  Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20080101

• Gateways to clinical trials. July-August 2008.

  Methods and findings in experimental and clinical pharmacology 20080101

• Dyslipidemia in primary care--prevalence, recognition, treatment and control: data from the German Metabolic and Cardiovascular Risk Project (GEMCAS).

  Cardiovascular diabetology 20080101

• Determination of nebivolol hydrochloride and hydrochlorothiazide in tablets by first-order derivative spectrophotometry and liquid chromatography.

  Journal of AOAC International 20080101

• Mild-to-moderate aortic stenosis not improved by lipid-lowering therapy: SEAS study.

  Cardiovascular journal of Africa 20080101

• Efficacy of statins in familial hypercholesterolaemia: a long term cohort study.

  BMJ (Clinical research ed.) 20080101

• Practical management of dyslipidemia with elevated lipoprotein(a).

  Journal of the American Pharmacists Association : JAPhA 20080101

• A randomised trial of three counselling strategies for lifestyle changes in patients with hypercholesterolemia treated with ezetimibe on top of statin therapy (TWICE).

  Archives of cardiovascular diseases 20080101

• Plant sterols/stanols as cholesterol lowering agents: A meta-analysis of randomized controlled trials.

  Food & nutrition research 20080101

• Cost effectiveness of ezetimibe in patients with cardiovascular disease and statin intolerance or contraindications: a Markov model.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20080101

• Diabetes: managing dyslipidaemia.

  BMJ clinical evidence 20080101

• UV and Three Derivative Spectrophotometric Methods for Determination of Ezetimibe in Tablet Formulation.

  Indian journal of pharmaceutical sciences 20080101

• Standardization of PCR-RFLP analysis of nsSNP rs1468384 of NPC1L1 gene.

  Indian journal of human genetics 20080101

• Ezetimibe improves liver steatosis and insulin resistance in obese rat model of metabolic syndrome.

  FEBS letters 20071211

• The effects of high dose pravastatin and low dose pravastatin and ezetimibe combination therapy on lipid, glucose metabolism and inflammation.

  Inflammation 20071201

• Disposition of the cholesterol absorption inhibitor ezetimibe in mdr1a/b (-/-) mice.

  Journal of pharmaceutical sciences 20071201

• Understanding practice patterns and low-density lipoprotein cholesterol goal attainment implications of switching patients from simvastatin in a health plan setting.

  The American journal of managed care 20071201

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20071201

• Practical guidelines for familial combined hyperlipidemia diagnosis: an up-date.

  Vascular health and risk management 20071201

• A retrospective study of the lipid-lowering efficacy and safety of ezetimibe added to hydroxy methylglutaryl coenzyme A reductase therapy in HIV-infected patients with hyperlipidemia.

  Journal of clinical lipidology 20071201

• Do mammalian NPC1 and NPC2 play a role in intestinal cholesterol absorption?

  The Biochemical journal 20071115

• Annexin A6-induced alterations in cholesterol transport and caveolin export from the Golgi complex.

  Traffic (Copenhagen, Denmark) 20071101

• Who needs to care about small, dense low-density lipoproteins?

  International journal of clinical practice 20071101

• [Type 1 diabetes: what are the alternatives for lowering cholesterol levels with statins?].

  Deutsche medizinische Wochenschrift (1946) 20071101

• Prevalence of adequate and of optimal control of serum low-density lipoprotein cholesterol in an academic nursing home.

  Journal of the American Medical Directors Association 20071101

• The pharmacologic elegance of inhibiting cholesterol absorption and synthesis while providing a homeostatic balance.

  Fundamental & clinical pharmacology 20071101

• Setting a new standard in achieving superior efficacy: ezetimibe + simvastatin.

  Fundamental & clinical pharmacology 20071101

• Cholesterol absorption inhibitors in the treatment of hyperlipidemia: clinical outcomes in large clinical trials.

  Fundamental & clinical pharmacology 20071101

• Lessons from 'lower' organisms: what worms, flies, and zebrafish can teach us about human energy metabolism.

  PLoS genetics 20071101

• Effects of ezetimibe/simvastatin on lipoprotein subfractions in patients with primary hypercholesterolemia: an exploratory analysis of archived samples using two commercially available techniques.

  Clinical therapeutics 20071101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20071101

• [LDL cholesterol in cardiovascular risk patients should be as low as possible].

  MMW Fortschritte der Medizin 20071011

• Effect of ezetimibe coadministered with statins in genotype-confirmed heterozygous FH patients.

  Atherosclerosis 20071001

• Differential effect of hypolipidemic drugs on lipoprotein-associated phospholipase A2.

  Arteriosclerosis, thrombosis, and vascular biology 20071001

• ISIS 301012 gene therapy for hypercholesterolemia: sense, antisense, or nonsense?

  The Annals of pharmacotherapy 20071001

• Effectiveness of statins in Medicare-eligible patients and patients < 65 years using clinical practice data.

  International journal of clinical practice 20071001

• FPIN's clinical inquiries. Best alternatives to statins for treating hyperlipidemia.

  American family physician 20071001

• [Severe progression of coronary heart disease in a patient with elevated lipoprotein (a) level in spite of optimal LDL-C decrease].

  Herz 20071001

• The role of HMG-CoA reductase inhibition in endothelial dysfunction and inflammation.

  Vascular health and risk management 20071001

• Cholesterol lowering for secondary prevention: what statin dose should we use?

  Vascular health and risk management 20071001

• Colesevelam hydrochloride: reducing atherosclerotic coronary heart disease risk factors.

  Vascular health and risk management 20071001

• Class B type I scavenger receptor is responsible for the high affinity cholesterol binding activity of intestinal brush border membrane vesicles.

  Biochimica et biophysica acta 20070901

• Cholesterol-lowering effect of ezetimibe in uridine diphosphate glucuronosyltransferase 1A-deficient (Gunn) rats.

  Drug metabolism and disposition: the biological fate of chemicals 20070901

• Age-induced hypercholesterolemia in the rat relates to reduced elimination but not increased intestinal absorption of cholesterol.

  American journal of physiology. Endocrinology and metabolism 20070901

• A multi-centre, randomised, double-blind 14-week extension study examining the long-term safety and efficacy profile of the ezetimibe/simvastatin combination tablet.

  International journal of clinical practice 20070901

• Human NPC1L1 and NPC1 can functionally substitute for the ncr genes to promote reproductive development in C. elegans.

  Biochimica et biophysica acta 20070901

• Reduction in estimated risk for coronary artery disease after use of ezetimibe with a statin.

  The Annals of pharmacotherapy 20070901

• [Rhabdomyolysis associated to combined ezetimibe-statin treatment].

  Revista clinica espanola 20070901

• Multiple plasma membrane receptors but not NPC1L1 mediate high-affinity, ezetimibe-sensitive cholesterol uptake into the intestinal brush border membrane.

  Biochimica et biophysica acta 20070901

• Effect of ezetimibe in patients who cannot tolerate statins or cannot get to the low density lipoprotein cholesterol target despite taking a statin.

  Current medical research and opinion 20070901

• Simvastatin: present and future perspectives.

  Expert opinion on pharmacotherapy 20070901

• The clinical relevance of LDL size and subclasses modulation in patients with type-2 diabetes.

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20070901

• Ezetimibe in search of receptor(s)--still a never-ending challenge in cholesterol absorption and transport.

  Biochimica et biophysica acta 20070901

• Ezetimibe in heart transplantation: initial experience.

  Transplantation proceedings 20070901

• Rational approach to the treatment for heterozygous familial hypercholesterolemia in childhood and adolescence: a review.

  Journal of endocrinological investigation 20070901

• Case reports: alopecia universalis: hair growth following initiation of simvastatin and ezetimibe therapy.

  Journal of drugs in dermatology : JDD 20070901

• [Drug of the month. Ezetimibe/simvastatin tablet (Inegy)].

  Revue medicale de Liege 20070901

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20070901

• Ezetimibe and simvastatin reduce inflammation, disease activity, and aortic stiffness and improve endothelial function in rheumatoid arthritis.

  Journal of the American College of Cardiology 20070828

• [New insights and perspectives in the management of dyslipidemia].

  La Revue de medecine interne 20070801

• Ezetimibe interferes with cholesterol trafficking from the plasma membrane to the endoplasmic reticulum in CaCo-2 cells.

  Journal of lipid research 20070801

• Therapy and clinical trials.

  Current opinion in lipidology 20070801

• Meta-analysis of the cholesterol-lowering effect of ezetimibe added to ongoing statin therapy.

  Current medical research and opinion 20070801

• Ezetimibe ameliorates cholecystosteatosis.

  Surgery 20070801

• Lipid-lowering agents that cause drug-induced hepatotoxicity.

  Clinics in liver disease 20070801

• New medications which decrease levothyroxine absorption.

  Thyroid : official journal of the American Thyroid Association 20070801

• Prolonged-release nicotinic acid for the management of dyslipidemia: an update including results from the NAUTILUS study.

  Vascular health and risk management 20070801

• Efficacy and tolerability of fixed-dose combination of simvastatin plus ezetimibe in patients with primary hypercholesterolemia: Results of a multicentric trial from India.

  Journal of clinical lipidology 20070801

• Further reduction of low-density lipoprotein cholesterol and C-reactive protein with the addition of ezetimibe to maximum-dose rosuvastatin in patients with severe hypercholesterolemia.

  Journal of clinical lipidology 20070801

• Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetimibe.

  The Journal of clinical investigation 20070702

• Efficacy of ezetimibe/simvastatin 10/20 and 10/40 mg compared with atorvastatin 20 mg in patients with type 2 diabetes mellitus.

  Diabetes, obesity & metabolism 20070701

• Effects of ezetimibe on lipids and lipoproteins in patients with hypercholesterolemia and different apolipoprotein E genotypes.

  Current medical research and opinion 20070701

• Tendon rupture associated with simvastatin/ezetimibe therapy.

  The American journal of cardiology 20070701

• Ezetimibe combines with simvastatin to tackle cholesterol. New drugs attack 'bad' cholesterol in the liver and intestine.

  Heart advisor 20070701

• A multicentre, open-label, observational local study to evaluate the low-density lipoprotein cholesterol-lowering effect of ezetimibe as prescribed in daily routine practice in the South African population.

  Cardiovascular journal of Africa 20070701

• Concurrent determination of ezetimibe and its phase-I and II metabolites by HPLC with UV detection: quantitative application to various in vitro metabolic stability studies and for qualitative estimation in bile.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070615

• Comparison of effects of ezetimibe/simvastatin versus simvastatin versus atorvastatin in reducing C-reactive protein and low-density lipoprotein cholesterol levels.

  The American journal of cardiology 20070615

• Comparative effects on lipid levels of combination therapy with a statin and extended-release niacin or ezetimibe versus a statin alone (the COMPELL study).

  Atherosclerosis 20070601

• Design and rationale of the ARBITER 6 trial (Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol)-6-HDL and LDL Treatment Strategies in Atherosclerosis (HALTS).

  Cardiovascular drugs and therapy 20070601

• Intestinal cholesterol transport proteins: an update and beyond.

  Current opinion in lipidology 20070601

• Ezetimibe: an update on the mechanism of action, pharmacokinetics and recent clinical trials.

  Expert opinion on drug metabolism & toxicology 20070601

• Ezetimibe plus fenofibrate: a new combination therapy for the management of mixed hyperlipidaemia?

  Expert opinion on pharmacotherapy 20070601

• Zetia: inhibition of Niemann-Pick C1 Like 1 (NPC1L1) to reduce intestinal cholesterol absorption and treat hyperlipidemia.

  Journal of atherosclerosis and thrombosis 20070601

• I am a 74-year-old woman who walks every day and am not overweight. I had a stent put in two-and-a-half years ago. I have high blood pressure and cholesterol problems. I have tried all the statins and every one causes muscle pains. The pain gets so bad that I cannot sleep at night. I watch my diet, but what else can I do to help myself?

  Heart advisor 20070601

• An update on the role of the quality of LDL in cardiovascular risk: the contribution of the universities of Palermo and Zurich.

  Recent patents on cardiovascular drug discovery 20070601

• Low-density lipoprotein-dependent and -independent effects of cholesterol-lowering therapies on C-reactive protein: a meta-analysis.

  Journal of the American College of Cardiology 20070522

• Statins targeting inflammation by lowering low-density lipoprotein?

  Journal of the American College of Cardiology 20070522

• Reducing the risks of cardiovascular disease in liver allograft recipients.

  Transplantation 20070515

• Drug-induced liver disease in 2006.

  Current opinion in gastroenterology 20070501

• Co-administration of ezetimibe and simvastatin in acute myocardial infarction.

  European journal of clinical investigation 20070501

• Safety of aggressive lipid management.

  Journal of the American College of Cardiology 20070501

• Effect of ezetimibe monotherapy on the concentration of lipoprotein subfractions in patients with primary dyslipidaemia.

  Current medical research and opinion 20070501

• [Statin and absorption inhibitor work synergistically. More risk patient reach LDL cholesterol goal value].

  MMW Fortschritte der Medizin 20070426

• [Change in the cholesterol metabolism associated with the combined inhibition of synthesis and absorption].

  Orvosi hetilap 20070408

• Deficiency of Niemann-Pick C1 Like 1 prevents atherosclerosis in ApoE-/- mice.

  Arteriosclerosis, thrombosis, and vascular biology 20070401

• Lysosomal unesterified cholesterol content correlates with liver cell death in murine Niemann-Pick type C disease.

  Journal of lipid research 20070401

• Effect of melatonin on cholesterol absorption in rats.

  Journal of pineal research 20070401

• Pharmacogenetics and pharmacogenomics of cholesterol-lowering therapy.

  Current opinion in lipidology 20070401

• Design and baseline characteristics of the simvastatin and ezetimibe in aortic stenosis (SEAS) study.

  The American journal of cardiology 20070401

• Dual cholesterol inhibition with ezetimibe/simvastatin in pre-treated hypercholesterolaemic patients with coronary heart disease or diabetes mellitus: prospective observational cohort studies in clinical practice.

  Current medical research and opinion 20070401

• Efficacy and safety of ezetimibe co-administered with atorvastatin in untreated patients with primary hypercholesterolaemia and coronary heart disease.

  Current medical research and opinion 20070401

• Did a flawed study design affect the results of the VYTAL study?

  Mayo Clinic proceedings 20070401

• Ezetimibe-induced acute pancreatitis.

  Southern medical journal 20070401

• Simvastatin + ezetimibe: a combination with no proven advantages.

  Prescrire international 20070401

• [Dual inhibition of cholesterol using the drug combination ezetimibe/simvastatin?].

  Vnitrni lekarstvi 20070401

• Safety considerations with gastrointestinally active lipid-lowering drugs.

  The American journal of cardiology 20070319

• Treatment with ezetimibe plus low-dose atorvastatin compared with higher-dose atorvastatin alone: is sufficient cholesterol-lowering enough to inhibit platelets?

  Journal of the American College of Cardiology 20070313

• The molecular mechanisms underlying the reduction of LDL apoB-100 by ezetimibe plus simvastatin.

  Journal of lipid research 20070301

• Efficacy and safety of rosuvastatin 40 mg alone or in combination with ezetimibe in patients at high risk of cardiovascular disease (results from the EXPLORER study).

  The American journal of cardiology 20070301

• Treatment of hypercholesterolemia with ezetimibe in cardiac transplant recipients.

  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070301

• [Synthesis plus absorption inhibitors are useful for high risk patients].

  Medizinische Monatsschrift fur Pharmazeuten 20070301

• [Reversible myopathy due to ezetimibe].

  Medicina clinica 20070217

• Discontinuation of lipid modifying drugs among commercially insured United States patients in recent clinical practice.

  The American journal of cardiology 20070215

• Niemann-Pick C1-like 1 overexpression facilitates ezetimibe-sensitive cholesterol and beta-sitosterol uptake in CaCo-2 cells.

  The Journal of pharmacology and experimental therapeutics 20070201

• The effect of simvastatin, ezetimibe and their combination on the lipid profile, arterial stiffness and inflammatory markers.

  European journal of clinical pharmacology 20070201

• Drug-induced liver injury associated with ezetimibe therapy.

  Digestive diseases and sciences 20070201

• Efficacy and safety of the coadministration of ezetimibe/simvastatin with fenofibrate in patients with mixed hyperlipidemia.

  American heart journal 20070201

• Myopathy associated with atorvastatin-ezetimibe combination therapy.

  Pharmacotherapy 20070201

• Lipid-lowering therapy--benefits and risks.

  The Israel Medical Association journal : IMAJ 20070201

• Lipid-lowering therapy--benefits and risks.

  The Israel Medical Association journal : IMAJ 20070201

• [Molecular diagnosis and combined lipid lowering therapy of heterozygous familial hypercholesterolemia. Report of one case].

  Revista medica de Chile 20070201

• Physiological and therapeutic factors affecting cholesterol metabolism: does a reciprocal relationship between cholesterol absorption and synthesis really exist?

  Life sciences 20070116

• Regulation of intestinal cholesterol absorption.

  Annual review of physiology 20070101

• In vivo responsiveness to ezetimibe correlates with niemann-pick C1 like-1 (NPC1L1) binding affinity: Comparison of multiple species NPC1L1 orthologs.

  Molecular pharmacology 20070101

• Ezetimibe analogs with a reorganized azetidinone ring: Design, synthesis, and evaluation of cholesterol absorption inhibitions.

  Bioorganic & medicinal chemistry letters 20070101

• Hepatic ABCG5/G8 overexpression reduces apoB-lipoproteins and atherosclerosis when cholesterol absorption is inhibited.

  Journal of lipid research 20070101

• Clinical importance and therapeutic modulation of small dense low-density lipoprotein particles.

  Expert opinion on biological therapy 20070101

• Sitosterol xanthomatosis.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20070101

• Fenofibrate: a review of its use in primary dyslipidaemia, the metabolic syndrome and type 2 diabetes mellitus.

  Drugs 20070101

• Ezetimibe added to statin therapy (EASY study) - an evaluation by Australian general practitioners.

  Australian family physician 20070101

• [Effect of hypolipidemic treatment on the composition of bile and the risk or cholesterol gallstone disease].

  Casopis lekaru ceskych 20070101

• Ezetimibe and fenofibrate combination therapy for mixed hyperlipidemia.

  Drugs of today (Barcelona, Spain : 1998) 20070101

• Psychiatric adverse reactions with statins, fibrates and ezetimibe: implications for the use of lipid-lowering agents.

  Drug safety 20070101

• Colesevelam hydrochloride-ezetimibe combination lipid-lowering therapy in patients with diabetes or metabolic syndrome and a history of statin intolerance.

  Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20070101

• Effectiveness and safety of ezetimibe added to statin therapy in patients with primary dyslipidaemia not achieving the LDL-C treatment goal on statin monotherapy.

  Clinical drug investigation 20070101

• [Influence of combined, hypolipemic therapy on lipids and non-lipid atherosclerosis risk factors].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20070101

• Ezetimibe is effective when added to maximally tolerated lipid lowering therapy in patients with HIV.

  Lipids in health and disease 20070101

• Effects of statins, fibrates, rosuvastatin, and ezetimibe beyond cholesterol: the modulation of LDL size and subclasses in high-risk patients.

  Advances in therapy 20070101

• [Recent treatment perspectives in lipidology].

  Revue medicale de Liege 20070101

• Aspirin and Simvastatin Combination for Cardiovascular Events Prevention Trial in Diabetes (ACCEPT-D): design of a randomized study of the efficacy of low-dose aspirin in the prevention of cardiovascular events in subjects with diabetes mellitus treated with statins.

  Trials 20070101

• An unusual exacerbation of chronic obstructive pulmonary disease (COPD) with herpes simplex tracheitis: case report.

  Journal of medical case reports 20070101

• Ezetimibe reduces low-density lipoprotein cholesterol (LDL-C) in renal transplant patients resistant to HMG-CoA reductase inhibitors.

  American journal of therapeutics 20070101

• [When should an association of lipid-lowering drugs be proposed in a patient failing to reach therapeutic targets under monotherapy? Guidelines of the New French Society of Atherosclerosis].

  Archives des maladies du coeur et des vaisseaux 20070101

• Stability-indicating reversed-phase liquid chromatographic method for simultaneous determination of simvastatin and ezetimibe from their combination drug products.

  Journal of AOAC International 20070101

• Are HIV positive patients resistant to statin therapy?

  Lipids in health and disease 20070101

• Stability-indicating reversed-phase liquid chromatographic method for simultaneous determination of atorvastatin and ezetimibe from their combination drug products.

  Journal of AOAC International 20070101

• Simultaneous liquid chromatographic determination of ezetimibe and simvastatin in pharmaceutical products.

  Journal of AOAC International 20070101

• [Functional state of endothelium and oxidant activity of leucocytes in patients with ischemic heart disease after coronary bypass surgery].

  Kardiologiia 20070101

• [Therapy of dyslipidemia in post-infarction: state of the art].

  La Clinica terapeutica 20070101

• Efficacy and safety of ezetimibe/simvastatin versus simvastatin monotherapy in hypercholesterolemic patients with metabolic syndrome.

  Metabolic syndrome and related disorders 20070101

• Ezetimibe: New perspectives in lipid lowering treatment.

  Cardiology journal 20070101

• Effect of Coenzyme Q10 and green tea on plasma and liver lipids, platelet aggregation, TBARS production and erythrocyte Na leak in simvastatin treated hypercholesterolmic rats.

  Nutrition research and practice 20070101

• The combination of Ezetimibe and Statin: a new treatment for hypercholesterolemia.

  Heart international 20070101

• Low-density lipoprotein apheresis: an evidence-based analysis.

  Ontario health technology assessment series 20070101

• The lipid-lowering effect of ezetimibe in pure vegetarians.

  Journal of lipid research 20061201

• Non-low-density lipoprotein cholesterol-associated actions of ezetimibe: an overview.

  Expert opinion on therapeutic targets 20061201

• Drug insight: the role of statins in combination with ezetimibe to lower LDL cholesterol.

  Nature clinical practice. Cardiovascular medicine 20061201

• Lipoprotein effects of combined ezetimibe and colesevelam hydrochloride versus ezetimibe alone in hypercholesterolemic subjects: a pilot study.

  Metabolism: clinical and experimental 20061201

• Ezetimibe/simvastatin vs atorvastatin in patients with type 2 diabetes mellitus and hypercholesterolemia: the VYTAL study.

  Mayo Clinic proceedings 20061201

• [Ezetimibe--intestinal cholesterol absorbtion inhibitor].

  Kardiologia polska 20061201

• Intensive lipid-lowering therapy: obvious benefits, possible risks.

  The Israel Medical Association journal : IMAJ 20061201

• Management of a patient with a null low-density lipoprotein receptor mutation: a case report.

  Angiology 20061201

• [New indications and therapeutic objectives for dyslipidemia].

  Atencion primaria 20061130

• Ezetimibe, a promising lipid-lowering agent for the treatment of dyslipidaemia in HIV-infected patients with poor response to statins.

  AIDS (London, England) 20061114

• Ezetimibe inhibits the incorporation of dietary oxidized cholesterol into lipoproteins.

  Journal of lipid research 20061101

• NPC1L1: evolution from pharmacological target to physiological sterol transporter.

  Arteriosclerosis, thrombosis, and vascular biology 20061101

• Cholesterol absorption inhibitors as a therapeutic option for hypercholesterolaemia.

  Expert opinion on investigational drugs 20061101

• Is combined treatment with fenofibrate and ezetimibe safe and efficacious in patients with mixed hyperlipidemia?

  Nature clinical practice. Cardiovascular medicine 20061101

• Lipid-lowering effects of colesevelam HCl in combination with ezetimibe.

  Current medical research and opinion 20061101

• Disposition and sterol-lowering effect of ezetimibe are influenced by single-dose coadministration of rifampin, an inhibitor of multidrug transport proteins.

  Clinical pharmacology and therapeutics 20061101

• [Cholesterol absorption as a target for the treatment of hypercholesterolemia].

  Harefuah 20061101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20061101

• Ezetimibe/simvastatin single tablet versus rosuvastatin in patients with hypercholesterolemia.

  Current medical research and opinion 20061001

• Lipid-altering efficacy of the ezetimibe/simvastatin single tablet versus rosuvastatin in hypercholesterolemic patients.

  Current medical research and opinion 20061001

• Efficacy and tolerability of ezetimibe 10 mg/day coadministered with statins in patients with primary hypercholesterolemia who do not achieve target LDL-C while on statin monotherapy: A Canadian, multicentre, prospective study--the Ezetrol Add-On Study.

  The Canadian journal of cardiology 20061001

• [Horse and rider].

  Medizinische Monatsschrift fur Pharmazeuten 20061001

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20061001

• Acute inhibition of lymphatic cholesterol transport in rat intestine by SCH 58053.

  Journal of atherosclerosis and thrombosis 20061001

• Management issues in the metabolic syndrome.

  The Journal of the Association of Physicians of India 20061001

• Disposition and sterol-lowering effect of ezetimibe in multidrug resistance-associated protein 2-deficient rats.

  The Journal of pharmacology and experimental therapeutics 20060901

• Rhabdomyolysis associated with pomegranate juice consumption.

  The American journal of cardiology 20060901

• Effectiveness of ezetimibe added to ongoing statin therapy in modifying lipid profiles and low-density lipoprotein cholesterol goal attainment in patients of different races and ethnicities: a substudy of the Ezetimibe add-on to statin for effectiveness trial.

  Mayo Clinic proceedings 20060901

• The clinical effect and tolerability of ezetimibe in high-risk patients managed in a specialty cardiovascular risk reduction clinic.

  The Canadian journal of cardiology 20060901

• Elevation of CKP induced by ezetimibe in monotherapy: report on two cases.

  Diabetes & metabolism 20060901

• Prospects for the development of novel anti-hyperlipidemic drugs.

  Current opinion in investigational drugs (London, England : 2000) 20060901

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20060901

• Stability indicating ultraviolet spectroscopic method for the estimation of ezetimibe and carvedilol.

  Die Pharmazie 20060901

• Ezetimibe added to ongoing statin therapy improves LDL-C goal attainment and lipid profile in patients with diabetes or metabolic syndrome.

  Diabetes & vascular disease research 20060901

• [Distinction between good synthesizer and good absorber patients to optimize cholesterol-lowering therapy].

  Revue medicale suisse 20060823

• Ezetimibe effectively decreases LDL-cholesterol in HIV-infected patients.

  AIDS (London, England) 20060801

• Efficacy, safety and LDL-C goal attainment of ezetimibe 10 mg-simvastatin 20 mg vs. placebo-simvastatin 20 mg in UK-based adults with coronary heart disease and hypercholesterolaemia.

  International journal of clinical practice 20060801

• Statins in the treatment of chronic heart failure: a systematic review.

  PLoS medicine 20060801

• Combination of statin and ezetimibe for the treatment of dyslipidemias and the prevention of coronary artery disease.

  The Canadian journal of cardiology 20060801

• [Lowering cholesterol: how low is low enough?].

  Orvosi hetilap 20060723

• Effect of insulin-sensitizing agents in combination with ezetimibe, and valsartan in rats with non-alcoholic fatty liver disease.

  World journal of gastroenterology 20060721

• Ezetimibe: effective and safe treatment for dyslipidaemia associated with nonalcoholic fatty liver disease. Response to: Toth PP, Davidson MH: simvastatin and ezetimibe: combination therapy for the management of dyslipidaemia. Expert Opin. Pharmacother. (2005) 6(1):131-139.

  Expert opinion on drug safety 20060701

• Severe hepatic side effects of ezetimibe.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20060701

• Total and low-density lipoprotein cholesterol responses to ezetimibe in clinical practice.

  International journal of clinical practice 20060701

• Combination therapy with ezetimibe and simvastatin to achieve aggressive LDL reduction.

  Expert review of cardiovascular therapy 20060701

• [Inegy: a powerful new medication for lowering LDL cholesterol].

  Revue medicale suisse 20060614

• Stress degradation studies on ezetimibe and development of a validated stability-indicating HPLC assay.

  Journal of pharmaceutical and biomedical analysis 20060607

• Hypolipidemic therapy for the metabolic syndrome.

  Pharmacological research 20060601

• The role of the Niemann-Pick C1-like 1 protein in the subcellular transport of multiple lipids and their homeostasis.

  Current opinion in lipidology 20060601

• Safety and effects on the lipid and C-reactive protein plasma concentration of the association of ezetimibe plus atorvastatin in renal transplant patients treated by cyclosporine-A: a pilot study.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20060601

• Comparison of the lipid-modifying efficacy and safety profiles of ezetimibe coadministered with simvastatin in older versus younger patients with primary hypercholesterolemia: a post Hoc analysis of subpopulations from three pooled clinical trials.

  Clinical therapeutics 20060601

• Rosuvastatin 5 and 10 mg/d: a pilot study of the effects in hypercholesterolemic adults unable to tolerate other statins and reach LDL cholesterol goals with nonstatin lipid-lowering therapies.

  Clinical therapeutics 20060601

• Dyslipidaemia in diabetes.

  Clinical evidence 20060601

• Fenofibrate: a novel formulation (Triglide) in the treatment of lipid disorders: a review.

  International journal of nanomedicine 20060601

• N,N'-carbonyldiimidazole-mediated cyclization of amino alcohols to substituted azetidines and other N-heterocycles.

  The Journal of organic chemistry 20060526

• The effect of ezetimibe on serum lipids and lipoproteins in patients with homozygous familial hypercholesterolemia undergoing LDL-apheresis therapy.

  Atherosclerosis 20060501

• Effect of ezetimibe on the in vivo kinetics of apoB-48 and apoB-100 in men with primary hypercholesterolemia.

  Arteriosclerosis, thrombosis, and vascular biology 20060501

• Lipid-lowering drugs.

  Cellular and molecular life sciences : CMLS 20060501

• Differential effects of short-term lipid lowering with ezetimibe and statins on endothelial function in patients with CAD: clinical evidence for 'pleiotropic' functions of statin therapy.

  European heart journal 20060501

• Effect of ezetimibe on low-density lipoprotein subtype distribution: results of a placebo-controlled, double-blind trial in patients treated by regular low-density lipoprotein apheresis and statins.

  Metabolism: clinical and experimental 20060501

• Selective compensatory induction of hepatic HMG-CoA reductase in response to inhibition of cholesterol absorption.

  Experimental biology and medicine (Maywood, N.J.) 20060501

• Type of preexisting lipid therapy predicts LDL-C response to ezetimibe.

  The Annals of pharmacotherapy 20060501

• Dose-comparison study of the combination of ezetimibe and simvastatin (Vytorin) versus atorvastatin in patients with hypercholesterolemia: the Vytorin Versus Atorvastatin (VYVA) Study.

  American heart journal 20060501

• Intestinal cholesterol absorption inhibitor ezetimibe added to cholestyramine for sitosterolemia and xanthomatosis.

  Gastroenterology 20060501

• Lower cholesterol without statins. Options are available.

  Mayo Clinic health letter (English ed.) 20060501

• Consistency of lipid-altering effects of ezetimibe/simvastatin across gender, race, age, baseline low density lipoprotein cholesterol levels, and coronary heart disease status: results of a pooled retrospective analysis.

  Current medical research and opinion 20060501

• Colesevelam hydrochloride in the management of dyslipidemia.

  Expert review of cardiovascular therapy 20060501

• Efficacy and safety of coadministration of ezetimibe and simvastatin in African-American patients with primary hypercholesterolemia.

  Journal of the National Medical Association 20060501

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20060501

• [Intensive cholesterol lowering therapy to reduce cardiovascular risk].

  Revista medica de Chile 20060501

• Is atorvastatin superior to other statins? Analysis of the clinical trials with atorvastatin having cardiovascular endpoints.

  Reviews on recent clinical trials 20060501

• Safety and efficacy of long-term co-administration of fenofibrate and ezetimibe in patients with mixed hyperlipidemia.

  Journal of the American College of Cardiology 20060418

• Serum plant sterols and atherosclerosis: is there a place for statin-ezetimibe combination?

  Journal of the American College of Cardiology 20060404

• A retrospective analysis of ezetimibe treatment in renal transplant recipients.

  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060401

• Drug utilization of ezetimibe in rehabilitation centres: registry analysis of factors influencing prescription and effectiveness of treatment.

  Current medical research and opinion 20060401

• Effect of ezetimibe on insulin sensitivity and lipid profile in obese and dyslipidaemic patients.

  Cardiovascular drugs and therapy 20060401

• [Treatment of dyslipidemia: how and when to combine lipid lowering drugs].

  Arquivos brasileiros de endocrinologia e metabologia 20060401

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20060401

• Ezetimibe in renal transplant patients with hyperlipidemia resistant to HMG-CoA reductase inhibitors.

  Transplantation 20060315

• Cholesterol-regulated translocation of NPC1L1 to the cell surface facilitates free cholesterol uptake.

  The Journal of biological chemistry 20060310

• Liquid chromatography-negative ion electrospray tandem mass spectrometry method for the quantification of ezetimibe in human plasma.

  Journal of pharmaceutical and biomedical analysis 20060303

• Ezetimib influences the expression of raft-associated antigens in human monocytes.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060301

• Monotherapy with ezetimibe causing myopathy.

  The American journal of medicine 20060301

• The second United Kingdom Heart and Renal Protection (UK-HARP-II) Study: a randomized controlled study of the biochemical safety and efficacy of adding ezetimibe to simvastatin as initial therapy among patients with CKD.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20060301

• Effects of ezetimibe on cyclosporine pharmacokinetics in healthy subjects.

  Journal of clinical pharmacology 20060301

• Interaction of single-dose ezetimibe and steady-state cyclosporine in renal transplant patients.

  Journal of clinical pharmacology 20060301

• Intestinal expression of P-glycoprotein (ABCB1), multidrug resistance associated protein 2 (ABCC2), and uridine diphosphate-glucuronosyltransferase 1A1 predicts the disposition and modulates the effects of the cholesterol absorption inhibitor ezetimibe in humans.

  Clinical pharmacology and therapeutics 20060301

• [Ezetimibe with statins].

  Presse medicale (Paris, France : 1983) 20060301

• Drug-induced effects on cholesterol catabolism and bile acids.

  Current opinion in investigational drugs (London, England : 2000) 20060301

• Reaching goal in hypercholesterolaemia: dual inhibition of cholesterol synthesis and absorption with simvastatin plus ezetimibe.

  Current medical research and opinion 20060301

• Evaluation of the potential for pharmacokinetic interaction between fenofibrate and ezetimibe: A phase I, open-label, multiple-dose, three-period crossover study in healthy subjects.

  Clinical therapeutics 20060301

• Complementary therapy to target LDL cholesterol: the role of the ezetimibe/simvastatin combination.

  Vascular health and risk management 20060301

• Effect of silymarin and its polyphenolic fraction on cholesterol absorption in rats.

  Pharmacological research 20060201

• Management of hyperlipidemia: new LDL-C targets for persons at high-risk for cardiovascular events.

  Medical science monitor : international medical journal of experimental and clinical research 20060201

• Ezetimibe-associated myopathy in monotherapy and in combination with a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor.

  The Canadian journal of cardiology 20060201

• Bioequivalence of an ezetimibe/simvastatin combination tablet and coadministration of ezetimibe and simvastatin as separate tablets in healthy subjects.

  International journal of clinical pharmacology and therapeutics 20060201

• Ezetimibe: rationale and role in the management of hypercholesterolemia.

  Clinical cardiology 20060201

• [Recurrent acute pancreatitis during pravastatin-therapy].

  Praxis 20060125

• Striated muscle safety of ezetimibe/simvastatin (Vytorin).

  The American journal of cardiology 20060115

• A LC-MS/MS method to quantify the novel cholesterol lowering drug ezetimibe in human serum, urine and feces in healthy subjects genotyped for SLCO1B1.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060102

• Inhibition of intestinal cholesterol absorption by ezetimibe is a novel therapeutic target for fatty liver.

  Medical hypotheses 20060101

• Clinical inquiries. What are effective medication combinations for dyslipidemia?

  The Journal of family practice 20060101

• Ezetimibe for the treatment of uncontrolled hypercholesterolemia in patients with high-dose statin therapy after renal transplantation.

  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060101

• The effects of statins on high-density lipoproteins.

  Current atherosclerosis reports 20060101

• Effective use of combination lipid therapy.

  Current atherosclerosis reports 20060101

• Rabbit small intestine does not contain an annexin II/caveolin 1 complex as a target for 2-azetidinone cholesterol absorption inhibitors.

  Biochimica et biophysica acta 20060101

• Effectiveness and tolerability of adding ezetimibe to niacin-based regimens for treatment of primary hyperlipidemia.

  Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20060101

• Cell receptors regulate cholesterol : ezetimibe blocks cholesterol absorption.

  Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20060101

• Unexpected beneficial effect in the use of ezetimibe in non-alcoholic fatty liver disease.

  Medical hypotheses 20060101

• Effect of ezetimibe and/or simvastatin on coenzyme Q10 levels in plasma: a randomised trial.

  Drug safety 20060101

• Cost effectiveness of adding ezetimibe to atorvastatin therapy in patients not at cholesterol treatment goal in Canada.

  PharmacoEconomics 20060101

• C-reactive protein (CRP)-lowering agents.

  Cardiovascular drug reviews 20060101

• Atherogenic dyslipidemia in metabolic syndrome and type 2 diabetes: therapeutic options beyond statins.

  Cardiovascular diabetology 20060101

• Airway smooth muscle as a target of asthma therapy: history and new directions.

  Respiratory research 20060101

• Familial dyslipidaemias: an overview of genetics, pathophysiology and management.

  Drugs 20060101

• Predictors of gallstone composition in 1025 symptomatic gallstones from Northern Germany.

  BMC gastroenterology 20060101

• Statins and solid organ transplantation.

  Current pharmaceutical design 20060101

• Drug interactions. Kaletra and ezetimibe.

  TreatmentUpdate 20060101

• [Combination of Zocor with Ezetrol].

  Revue medicale de Bruxelles 20060101

• Combination of a sterol absorption inhibitor and cardiovascular agents for the treatment of dyslipidemia.

  Recent patents on cardiovascular drug discovery 20060101

• Inhibition of cholesterol absorption by the combination of dietary plant sterols and ezetimibe: effects on plasma lipid levels.

  Journal of lipid research 20051201

• Therapy and clinical trials.

  Current opinion in lipidology 20051201

• Comment: supratherapeutic response to ezetimibe administered with cyclosporine.

  The Annals of pharmacotherapy 20051201

• Sequence variation in NPC1L1 and association with improved LDL-cholesterol lowering in response to ezetimibe treatment.

  Genomics 20051201

• Lipid-altering efficacy of switching from atorvastatin 10 mg/day to ezetimibe/simvastatin 10/20 mg/day compared to doubling the dose of atorvastatin in hypercholesterolaemic patients with atherosclerosis or coronary heart disease.

  International journal of clinical practice 20051201

• Ezetimibe/simvastatin (INEGY) in the treatment of hyperlipidaemia.

  International journal of clinical practice 20051201

• Effectiveness of the addition of ezetimibe to ongoing statin therapy in modifying lipid profiles and attaining low-density lipoprotein cholesterol goals in older and elderly patients: subanalyses of data from a randomized, double-blind, placebo-controlled trial.

  The American journal of geriatric pharmacotherapy 20051201

• Cholesterol absorption blockade with ezetimibe.

  Current drug targets. Cardiovascular & haematological disorders 20051201

• Optimal lipid modification: the rationale for combination therapy.

  Vascular health and risk management 20051201

• Ezetimibe/Simvastatin (vytorin) for hypercholesterolemia.

  American family physician 20051115

• [How can lipid therapy be improved? Cardiologists insist on dual cholesterol inhibition].

  MMW Fortschritte der Medizin 20051110

• [Cholesterol goals are now easier to reach. Half LDL cholesterol with only one tablet daily].

  MMW Fortschritte der Medizin 20051110

• Rationale for targeting multiple lipid pathways for optimal cardiovascular risk reduction.

  The American journal of cardiology 20051107

• High-density lipoprotein as a therapeutic target: clinical evidence and treatment strategies.

  The American journal of cardiology 20051107

• [Type 2 diabetics are high risk patients. Concerning LDL-cholesterol to approach effectively to two sources].

  MMW Fortschritte der Medizin 20051103

• Ezetimibe coadministered with fenofibrate: some safety questions.

  European heart journal 20051101

• Cholesterol absorption: influence of body weight and the role of plant sterols.

  Current atherosclerosis reports 20051101

• Effective use of combination lipid therapy.

  Current cardiology reports 20051101

• Lipids for psychiatrists - an overview.

  Journal of psychopharmacology (Oxford, England) 20051101

• [MMW- Drug Prize 2005 for simvastatin/ezetimib (Inegy). LDL goal values are easier to reach now].

  MMW Fortschritte der Medizin 20051027

• Heterocyclic ring scaffolds as small-molecule cholesterol absorption inhibitors.

  Organic & biomolecular chemistry 20051007

• Carotenoid transport is decreased and expression of the lipid transporters SR-BI, NPC1L1, and ABCA1 is downregulated in Caco-2 cells treated with ezetimibe.

  The Journal of nutrition 20051001

• [Clinical efficacy of ezetimibe and combined use with statins].

  Revista clinica espanola 20051001

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20051001

• [Ezetimibe--pharmacokinetics and therapeutics].

  Arquivos brasileiros de cardiologia 20051001

• [Hypolipidemic therapy in special situations: hypothyroidism and liver disease].

  Arquivos brasileiros de cardiologia 20051001

• Ezetimibe: a turbocharger for the race to reach NCEP LDL goals.

  South Dakota journal of medicine 20051001

• [New results in the management of hypercholesterolemia].

  Orvosi hetilap 20050925

• Synthesis and in vitro evaluation of inhibitors of intestinal cholesterol absorption.

  Journal of medicinal chemistry 20050922

• Development and validation of a reversed-phase HPLC method for the determination of ezetimibe in pharmaceutical dosage forms.

  Journal of pharmaceutical and biomedical analysis 20050915

• Supratherapeutic response to ezetimibe administered with cyclosporine.

  The Annals of pharmacotherapy 20050901

• Drug-induced acute autoimmune hepatitis during combination therapy with atorvastatin and ezetimibe.

  Annals of clinical biochemistry 20050901

• [Innovative therapies in metabolic diseases: ezetimibe (Ezétrol), nicotinic acid (Niaspan), acids omega-3 (Omacor), rimonabant (Acomplia)].

  Revue medicale de Bruxelles 20050901

• Model-based development of gemcabene, a new lipid-altering agent.

  The AAPS journal 20050901

• Pharmacologic options for aggressive low-density lipoprotein cholesterol lowering: benefits versus risks.

  The American journal of cardiology 20050822

• Ezetimibe normalizes metabolic defects in mice lacking ABCG5 and ABCG8.

  Journal of lipid research 20050801

• The effect of fluvastatin on the pharmacokinetics and pharmacodynamics of ezetimibe.

  Current medical research and opinion 20050801

• New insights into the genetic regulation of intestinal cholesterol absorption.

  Gastroenterology 20050801

• Caveolin-1 is not required for murine intestinal cholesterol transport.

  The Journal of biological chemistry 20050729

• Effect of co-administering ezetimibe with on-going simvastatin treatment on LDL-C goal attainment in hypercholesterolemic patients with coronary heart disease.

  International journal of cardiology 20050710

• [Ezetimib and simvastatin. Cooperation at receptors of cholesterol metabolism].

  MMW Fortschritte der Medizin 20050707

• [Goal in hypercholesterolemia: lowering LDL cholesterol level by 50%].

  MMW Fortschritte der Medizin 20050707

• Cholesterol and plant sterol absorption: recent insights.

  The American journal of cardiology 20050704

• In response to 'ezetimibe-induced hyperlipidaemia' case report.

  International journal of clinical practice 20050701

• European Atherosclerosis Society--75th congress.

  IDrugs : the investigational drugs journal 20050701

• Lipid altering-efficacy of ezetimibe co-administered with simvastatin compared with rosuvastatin: a meta-analysis of pooled data from 14 clinical trials.

  Current medical research and opinion 20050701

• [Can we prevent the progression of aortic valve sclerosis and stenosis? The need for a prospective, randomized trial].

  Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20050701

• [Lowering LDL cholesterol frequently does not adhere to guidelines. Also regard intestinal cholesterol source].

  MMW Fortschritte der Medizin 20050609

• The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1).

  Proceedings of the National Academy of Sciences of the United States of America 20050607

• [Selective cholesterol absorption inhibition as a new prospect in treatment of hypercholesterolemia].

  Medicina clinica 20050604

• Worsening myopathy associated with ezetimibe in a patient with McArdle disease.

  QJM : monthly journal of the Association of Physicians 20050601

• Efficacy and safety of ezetimibe co-administered with ongoing atorvastatin therapy in achieving low-density lipoprotein goal in patients with hypercholesterolemia and coronary heart disease.

  International journal of clinical practice 20050601

• The use of ezetimibe in achieving low density lipoprotein lowering goals in clinical practice: position statement of a United Kingdom consensus panel.

  Current medical research and opinion 20050601

• [Innovation instead of imitation -- news in drug therapy -- regarding the contribution in DMW 13/2005].

  Deutsche medizinische Wochenschrift (1946) 20050520

• Simvastatin versus ezetimibe: pleiotropic and lipid-lowering effects on endothelial function in humans.

  Circulation 20050510

• Efficacy and safety of the coadministration of ezetimibe with fenofibrate in patients with mixed hyperlipidaemia.

  European heart journal 20050501

• Management of mixed hyperlipidaemia.

  European heart journal 20050501

• Effects of ezetimibe on plasma lipoproteins in severely hypercholesterolemic patients treated with regular LDL-apheresis and statins.

  Atherosclerosis 20050501

• [Optimization of cholesterol reduction principles and clinical results of dual inhibition].

  Der Internist 20050501

• Getting there: statin plus ezetimibe for low-density lipoprotein cholesterol goals.

  Mayo Clinic proceedings 20050501

• A community-based, randomized trial of ezetimibe added to statin therapy to attain NCEP ATP III goals for LDL cholesterol in hypercholesterolemic patients: the ezetimibe add-on to statin for effectiveness (EASE) trial.

  Mayo Clinic proceedings 20050501

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20050501

• Enhanced hypercholesterolemia therapy: the ezetimibe/simvastatin tablet.

  Drugs of today (Barcelona, Spain : 1998) 20050501

• Characterization of the putative native and recombinant rat sterol transporter Niemann-Pick C1 Like 1 (NPC1L1) protein.

  Biochimica et biophysica acta 20050415

• Delineation of molecular changes in intrahepatic cholesterol metabolism resulting from diminished cholesterol absorption.

  Journal of lipid research 20050401

• Effects of ezetimibe coadministered with simvastatin on C-reactive protein in a large cohort of hypercholesterolemic patients.

  Atherosclerosis 20050401

• Projected coronary heart disease risk benefit with ezetimibe.

  Atherosclerosis 20050401

• UDP-glucuronosyltransferases and clinical drug-drug interactions.

  Pharmacology & therapeutics 20050401

• [Innovation instead of imitation -- news in drug therapy].

  Deutsche medizinische Wochenschrift (1946) 20050401

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20050401

• What is the best strategy for reducing deaths from heart disease?

  PLoS medicine 20050401

• Ezetimibe-induced hyperlipidaemia.

  International journal of clinical practice. Supplement 20050401

• LDL-C goal attainment with the addition of ezetimibe to ongoing simvastatin treatment in coronary heart disease patients with hypercholesterolemia.

  Current medical research and opinion 20050401

• Class B scavenger receptor-mediated intestinal absorption of dietary beta-carotene and cholesterol.

  Biochemistry 20050322

• Carbohydrate sulfonyl chlorides for simple, convenient access to glycoconjugates.

  Organic letters 20050317

• Drugs for lipids.

  Treatment guidelines from the Medical Letter 20050301

• Sterol transporters: targets of natural sterols and new lipid lowering drugs.

  Pharmacology & therapeutics 20050301

• The dyslipidemia of diabetes mellitus: giving triglycerides and high-density lipoprotein cholesterol a higher priority?

  Endocrinology and metabolism clinics of North America 20050301

• Drug treats two sources of cholesterol.

  The Nurse practitioner 20050301

• Efficacy of ezetimibe in patients with statin-resistant and statin-intolerant familial hyperlipidaemias.

  Current medical research and opinion 20050301

• [Approved indication for Ezetrol].

  Lakartidningen 20050301

• Management of dyslipidemia in women in the post-hormone therapy era.

  Journal of general internal medicine 20050301

• Treatment of hypercholesterolemia with ezetimibe in the kidney transplant population.

  Transplantation proceedings 20050301

• [Ezetimibe].

  Revue de l'infirmiere 20050301

• Dose-comparison study of the combination of ezetimibe and simvastatin (Vytorin) versus atorvastatin in patients with hypercholesterolemia: the Vytorin Versus Atorvastatin (VYVA) study.

  American heart journal 20050301

• Ongoing clinical trials of the pleiotropic effects of statins.

  Vascular health and risk management 20050301

• Help for your cholesterol when statins won't do. If you are one of the many, but also one of the few..

  Harvard men's health watch 20050301

• Cerebral cholesterol granuloma in homozygous familial hypercholesterolemia.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050215

• [Ezetimibe and safety].

  Ugeskrift for laeger 20050214

• Compound heterozygosity for two non-synonymous polymorphisms in NPC1L1 in a non-responder to ezetimibe.

  Clinical genetics 20050201

• Rationale for combination therapy with statin drugs in the treatment of dyslipidemia.

  Current atherosclerosis reports 20050201

• Zetia and Zocor: good together? New combo pill Vytorin may help some reach low LDL goals.

  Harvard health letter 20050201

• Long-term safety and, tolerability profiles and lipid-modifying efficacy of ezetimibe coadministered with ongoing simvastatin treatment: a multicenter, randomized, double-blind, placebo-controlled, 48-week extension study.

  Clinical therapeutics 20050201

• Comparison of ezetimibe plus simvastatin versus simvastatin monotherapy on atherosclerosis progression in familial hypercholesterolemia. Design and rationale of the Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression (ENHANCE) trial.

  American heart journal 20050201

• Aminopeptidase N (CD13) is a molecular target of the cholesterol absorption inhibitor ezetimibe in the enterocyte brush border membrane.

  The Journal of biological chemistry 20050114

• [How sure is the combined lipid lowering?].

  MMW Fortschritte der Medizin 20050113

• [New therapeutic alternative to aggressive statin treatment].

  Ugeskrift for laeger 20050110

• Effect of high plant sterol-enriched diet and cholesterol absorption inhibitor, SCH 58235, on plant sterol absorption and plasma concentrations in hypercholesterolemic wild-type Kyoto rats.

  Metabolism: clinical and experimental 20050101

• An ezetimibe-policosanol combination has the potential to be an OTC agent that could dramatically lower LDL cholesterol without side effects.

  Medical hypotheses 20050101

• Isolated low high density lipoprotein-cholesterol (HDL-C): implications of global risk reduction. Case report and systematic scientific review.

  Cardiovascular diabetology 20050101

• Efficacy and safety of ezetimibe co-administered with simvastatin in thiazolidinedione-treated type 2 diabetic patients.

  Diabetes, obesity & metabolism 20050101

• Ezetimibe plus simvastatin lowered lipid levels more than simvastatin monotherapy in primary hypercholesterolemia.

  ACP journal club 20050101

• Changes in lipids over twelve months after initiating protease inhibitor therapy among persons treated for HIV/AIDS.

  Lipids in health and disease 20050101

• Simvastatin plus ezetimibe: combination therapy for the management of dyslipidaemia.

  Expert opinion on pharmacotherapy 20050101

• Cost-effectiveness of statin monotherapy and combination therapy with ezetimibe.

  Connecticut medicine 20050101

• Cholesterol. How low should we go?

  Saudi medical journal 20050101

• Achieving synergy and improvements in cholesterol lowering.

  Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20050101

• By the way, doctor. I take 20 mg of Lipitor and 10 mg of Zetia. My total cholesterol has declined from 177 to 145, my LDL from 133 to 93, but my 'good' HDL cholesterol also went down from 46 to 41. Would you consider my low HDL level a large risk factor? If so, is there a regimen that would increase it?

  Harvard health letter 20050101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20050101

• Ezetimibe and other azetidinone cholesterol absorption inhibitors.

  Current topics in medicinal chemistry 20050101

• Ezetimibe: a review of its metabolism, pharmacokinetics and drug interactions.

  Clinical pharmacokinetics 20050101

• Effect of rosuvastatin on outcomes in chronic haemodialysis patients - design and rationale of the AURORA study.

  Current controlled trials in cardiovascular medicine 20050101

• Statins research unfinished saga: desirability versus feasibility.

  Cardiovascular diabetology 20050101

• Targets for low-density lipoprotein cholesterol levels in patients with stable coronary heart disease: where are we now after the 'treating to new targets' (TNT) trial?

  Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20050101

• Colesevelam HCl and ezetimibe combination therapy provides effective lipid-lowering in difficult-to-treat patients with hypercholesterolemia.

  American journal of therapeutics 20050101

• Ezetimibe offers new opportunity to lower LDL-C to target levels.

  Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20050101

• The SPHERE Study. Secondary prevention of heart disease in general practice: protocol of a randomised controlled trial of tailored practice and patient care plans with parallel qualitative, economic and policy analyses. [ISRCTN24081411].

  Current controlled trials in cardiovascular medicine 20050101

• NPC1L1 haplotype is associated with inter-individual variation in plasma low-density lipoprotein response to ezetimibe.

  Lipids in health and disease 20050101

• Endothelial function in the forearm circulation of patients with the metabolic syndrome--effect of different lipid-lowering regimens.

  Cardiology 20050101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20050101

• [Ezetimib--inhibitor of cholesterol absorption: new perspectives in the treatment of dyslipidemia].

  Terapevticheskii arkhiv 20050101

• Treatment of dyslipidemia with lovastatin and ezetimibe in an adolescent with cholesterol ester storage disease.

  Lipids in health and disease 20050101

• Focus on improving lipid-lowering efficacy at ESC - Stockholm, September 2005.

  Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20050101

• LDL-C goal attainment with ezetimibe plus simvastatin coadministration vs atorvastatin or simvastatin monotherapy in patients at high risk of CHD.

  MedGenMed : Medscape general medicine 20050101

• [Risk adapted therapy of vascular diseases--basic therapy of dys- and hyperlipoproteinemia].

  Zeitschrift fur Kardiologie 20050101

• The ABC of hepatic and intestinal cholesterol transport.

  Handbook of experimental pharmacology 20050101

• [Coronary heart disease patient reaches LDL level of 100 mg/dl with atorvastatin: how do you continue treatment next year?].

  MMW Fortschritte der Medizin 20041216

• Phenotypic heterogeneity of sitosterolemia.

  Journal of lipid research 20041201

• Lipids in health and disease.

  Biochemical Society transactions 20041201

• Simvastatin: a review.

  Expert opinion on pharmacotherapy 20041201

• Pharmacologic treatment of type 2 diabetic dyslipidemia.

  Pharmacotherapy 20041201

• Lipid-lowering drugs.

  Nursing older people 20041201

• Consistency in efficacy and safety of ezetimibe coadministered with statins for treatment of hypercholesterolemia in women and men.

  Journal of women's health (2002) 20041201

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20041201

• Autosomal recessive hypercholesterolaemia: normalization of plasma LDL cholesterol by ezetimibe in combination with statin treatment.

  Journal of internal medicine 20041101

• Ezetimibe: a novel cholesterol-lowering agent that highlights novel physiologic pathways.

  Current cardiology reports 20041101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20041101

• A multicenter, randomized, double-blind, placebo-controlled, factorial design study to evaluate the lipid-altering efficacy and safety profile of the ezetimibe/simvastatin tablet compared with ezetimibe and simvastatin monotherapy in patients with primary hypercholesterolemia.

  Clinical therapeutics 20041101

• Lipid-lowering medications.

  Pediatric endocrinology reviews : PER 20041101

• [Target values are more often attainable. Almost doubly so many patients with values under 100mg/dl].

  MMW Fortschritte der Medizin 20041028

• Ezetimibe and statin-associated myopathy.

  Annals of internal medicine 20041019

• [The role of intestinal absorption blockade in hypercholesterolemia treatment].

  Revista clinica espanola 20041001

• Ezetimibe: new preparation. A cholesterol-lowering drug with no clinical advantage.

  Prescrire international 20041001

• [Ezetimibe (Ezetrol): the statins' partner].

  Revue medicale de Bruxelles 20041001

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20041001

• [Ezetimib].

  Deutsche medizinische Wochenschrift (1946) 20040924

• Disruption of cholesterol homeostasis by plant sterols.

  The Journal of clinical investigation 20040915

• Effectiveness and tolerability of ezetimibe add-on therapy to a bile acid resin-based regimen for hypercholesterolemia.

  The American journal of cardiology 20040915

• Vytorin: a combination of ezetimibe and simvastatin.

  The Medical letter on drugs and therapeutics 20040913

• Ezetimibe--a new cholesterol-lowering drug.

  Drug and therapeutics bulletin 20040901

• Effects of ezetimibe added to on-going statin therapy on the lipid profile of hypercholesterolemic patients with diabetes mellitus or metabolic syndrome.

  Current medical research and opinion 20040901

• Pharmacokinetic interaction between ezetimibe and lovastatin in healthy volunteers.

  Current medical research and opinion 20040901

• Achieving lipoprotein goals in patients at high risk with severe hypercholesterolemia: efficacy and safety of ezetimibe co-administered with atorvastatin.

  American heart journal 20040901

• Coadministration of multidrug therapy to achieve lipid goals.

  The Journal of the American Osteopathic Association 20040901

• Assessment of a multiple-dose drug interaction between ezetimibe, a novel selective cholesterol absorption inhibitor and gemfibrozil.

  International journal of clinical pharmacology and therapeutics 20040901

• Ezetimibe + simvastatin (Merck/Schering-Plough).

  Current opinion in investigational drugs (London, England : 2000) 20040901

• New drugs.

  Canadian family physician Medecin de famille canadien 20040901

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20040901

• Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis.

  The Journal of biological chemistry 20040806

• Cholesterol absorption inhibitor Ezetimibe blocks uptake of oxidized LDL in human macrophages.

  Biochemical and biophysical research communications 20040806

• Current management of severe homozygous hypercholesterolaemias.

  Current opinion in lipidology 20040801

• Combination therapy in the management of complex dyslipidemias.

  Current opinion in lipidology 20040801

• Treatment of hyperlipidemia in cardiac transplant recipients.

  American heart journal 20040801

• Pharmacodynamic interaction between ezetimibe and rosuvastatin.

  Current medical research and opinion 20040801

• Pharmacodynamic and pharmacokinetic interaction between fenofibrate and ezetimibe.

  Current medical research and opinion 20040801

• Efficacy and safety of ezetimibe coadministered with statins: randomised, placebo-controlled, blinded experience in 2382 patients with primary hypercholesterolemia.

  International journal of clinical practice 20040801

• [Ezetimib--a new possibility for combined therapy in hypercholesterolemia].

  Vnitrni lekarstvi 20040801

• New strategies in the treatment of dyslipidemia: do we know how?

  Seminars in vascular medicine 20040801

• Statins as the cornerstone of drug therapy for dyslipidemia: monotherapy and combination therapy options.

  American heart journal 20040701

• Beta-lactam cholesterol absorption inhibitors.

  Current medicinal chemistry 20040701

• Long-term safety and tolerability profile of ezetimibe and atorvastatin coadministration therapy in patients with primary hypercholesterolaemia.

  International journal of clinical practice 20040701

• The effects of ezetimibe on the LDL-cholesterol particle number.

  Cardiovascular drugs and therapy 20040701

• Treatment of high-risk patients with ezetimibe plus simvastatin co-administration versus simvastatin alone to attain National Cholesterol Education Program Adult Treatment Panel III low-density lipoprotein cholesterol goals.

  The American journal of cardiology 20040615

• Efficacy and safety of ezetimibe co-administered with simvastatin compared with atorvastatin in adults with hypercholesterolemia.

  The American journal of cardiology 20040615

• [Can ezetimib also be used as a treatment for beta-sitosterol].

  Deutsche medizinische Wochenschrift (1946) 20040611

• Effects of ezetimibe on the pharmacodynamics and pharmacokinetics of lovastatin.

  Current medical research and opinion 20040601

• New drug may help when statin response is low.

  Harvard heart letter : from Harvard Medical School 20040601

• How doubling up drugs saves lives. Why doctors increasingly deploy an array of medications all at once.

  Heart advisor 20040601

• Cholesterol metabolism and therapeutic targets: rationale for targeting multiple metabolic pathways.

  Clinical cardiology 20040601

• Optimizing lipid lowering in patients at risk.

  Clinical cardiology 20040601

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20040601

• [New combination therapy. Up to 60% lower LDL cholesterol level].

  MMW Fortschritte der Medizin 20040506

• Efficacy and safety of ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia: a randomized, double-blind, placebo-controlled trial.

  Mayo Clinic proceedings 20040501

• Statin pleiotropy: fact or fiction?

  American journal of critical care : an official publication, American Association of Critical-Care Nurses 20040501

• Hypolipidemic treatment of heterozygous familial hypercholesterolemia: a lifelong challenge.

  Expert review of cardiovascular therapy 20040501

• A statin for a patient with hyperlipidemia and hepatitis C?

  Postgraduate medicine 20040501

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20040501

• Ezetimibe and statin-associated myopathy.

  Annals of internal medicine 20040420

• [New treatment option for decreasing blood cholesterol level--clinical significance of inhibition of both, cholesterol absorption and synthesis].

  Orvosi hetilap 20040411

• On call. I'm a 63-year-old man with arthritis but no other conditions. My only medicines were Naprosyn and vitamins until my last annual checkup, when my cholesterol was high. My doctor gave me Zocor, which helped. But I developed muscle aches, so he switched me to Zetia. I feel fine again, but I'd like to know what you think.

  Harvard men's health watch 20040401

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20040401

• [Ezetimibe (Ezetrol)].

  Revue medicale de Liege 20040401

• [Recommended LDL value far lower. How does one achieve this goal?].

  MMW Fortschritte der Medizin 20040325

• Stenosis and the drug-eluting stent.

  Circulation 20040323

• Initial low-density lipoprotein response to statin therapy predicts subsequent low-density lipoprotein response to the addition of ezetimibe.

  The American journal of cardiology 20040315

• Two more drugs for dyslipidemia.

  The American journal of cardiology 20040315

• Ezetimibe effectively reduces plasma plant sterols in patients with sitosterolemia.

  Circulation 20040302

• Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia).

  Drug metabolism and disposition: the biological fate of chemicals 20040301

• Effectiveness of ezetimibe in clinical practice.

  The American journal of cardiology 20040301

• Hypolipidemic therapy and cholesterol absorption.

  Current atherosclerosis reports 20040301

• By the way, doctor. I've recently heard about a new cholesterol drug called Zetia. Does it work better than a statin?

  Harvard women's health watch 20040301

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20040301

• Biomedicine. Will the real cholesterol transporter please stand up.

  Science (New York, N.Y.) 20040220

• Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption.

  Science (New York, N.Y.) 20040220

• Homozygous hypercholesterolaemia and ezetimibe: a case report.

  Acta paediatrica (Oslo, Norway : 1992) 20040201

• Lipids and atherosclerosis.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20040201

• Lipid lowering activity of drugs affecting cholesterol absorption.

  Nutrition, metabolism, and cardiovascular diseases : NMCD 20040201

• Homozygous familial hypercholesterolemia and its management.

  Seminars in vascular medicine 20040201

• Role of selective cholesterol absorption inhibition in the management of dyslipidemia.

  Current atherosclerosis reports 20040101

• The discovery of ezetimibe: a view from outside the receptor.

  Journal of medicinal chemistry 20040101

• Optimizing LDL-C lowering with statins.

  American journal of therapeutics 20040101

• Plant sterols: factors affecting their efficacy and safety as functional food ingredients.

  Lipids in health and disease 20040101

• Treatment of hyperlipidemia in elderly persons with exercise training, nonpharmacologic therapy, and drug combinations.

  The American journal of geriatric cardiology 20040101

• New developments in pharmacotherapy.

  Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20040101

• Medical lipid-regulating therapy: current evidence, ongoing trials and future developments.

  Drugs 20040101

• Safety and tolerability of ezetimibe.

  The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20040101

• [Blocking the absorption of cholesterol in the treatment of hyperlipidemia--old and new ways of treatment].

  Duodecim; laaketieteellinen aikakauskirja 20040101

• Preventing clinically evident coronary heart disease in the postmenopausal woman.

  Menopause (New York, N.Y.) 20040101

• The pivotal role of cholesterol absorption inhibitors in the management of dyslipidemia.

  Lipids in health and disease 20040101

• [Some new drugs: valdecoxib (Betra), voriconazole (Vfend), ezetimide (Ezetrol), teriparatide (Forsteo)].

  Journal de pharmacie de Belgique 20040101

• Ezetimibe/Simvastatin: a review of its use in the management of hypercholesterolemia.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20040101

• Comparative effects of lipid-lowering therapies.

  Progress in cardiovascular diseases 20040101

• Lipid metabolism in zebrafish.

  Methods in cell biology 20040101

• Efficacy and safety of coadministration of ezetimibe and statins in elderly patients with primary hypercholesterolaemia.

  Drugs & aging 20040101

• Development and validation of a model to project the long-term benefit and cost of alternative lipid-lowering strategies in patients with hypercholesterolaemia.

  PharmacoEconomics 20040101

• Cost-effectiveness of ezetimibe coadministration in statin-treated patients not at cholesterol goal: application to Germany, Spain and Norway.

  PharmacoEconomics 20040101

• Effect of coadministration of ezetimibe and simvastatin on high-sensitivity C-reactive protein.

  The American journal of cardiology 20031215

• [Hyperlipidemia: therapeutic principles in clinical practice].

  Medizinische Klinik (Munich, Germany : 1983) 20031215

• [Even at LDL cholesterol 100mg/dl. 'Every coronary disease patient has to receive a statin'].

  MMW Fortschritte der Medizin 20031204

• Therapy and clinical trials: ezetimibe.

  Current opinion in lipidology 20031201

• [Ezetimibe: from pharmacology to clinical trials].

  Annales d'endocrinologie 20031201

• Genetic regulation of cholesterol absorption and plasma plant sterol levels: commonalities and differences.

  Journal of lipid research 20031101

• Newer pharmaceutical agents to treat lipid disorders.

  Current cardiology reports 20031101

• New drugs for the treatment of hypercholesterolaemia.

  Expert opinion on investigational drugs 20031101

• Pharmacotherapy for dyslipidaemia--current therapies and future agents.

  Expert opinion on pharmacotherapy 20031101

• Ezetimibe: a selective cholesterol absorption inhibitor.

  Pharmacotherapy 20031101

• Cholesterol absorption inhibitors: a closer look.

  Advance for nurse practitioners 20031101

• Avoid the risks of mixed medications. How to minimize dangerous interactions with cardiovascular drugs.

  Heart advisor 20031101

• Ezetimibe for hypercholesterolemia.

  American family physician 20031015

• The antilipidemic effects of ezetimibe in patients with diabetes.

  Diabetes care 20031001

• Ask the doctor. I am a 64-year-old woman with high cholesterol caused by bad genes (familial hypercholesterolemia). Without medication, my cholesterol is above 450 mg/dL. So I am taking high-dose Lipitor (80 mg/day), WelChol, and Zetia to lower my cholesterol. I sometimes have pain and stiffness in my knees, and my shoulder, elbow, and wrist joints, plus the muscles in between, are stiff in the morning and hurt during the day. Two years ago I was diagnosed with bursitis in my hips. Could these problems be f

  Harvard heart letter : from Harvard Medical School 20031001

• Ezetimibe: a new addition to lipid-lowering therapy.

  International journal of clinical practice 20031001

• Ezetimibe plus atorvastatin lowers cholesterol.

  The Journal of family practice 20030901

• Lipid-lowering: can ezetimibe help close the treatment gap?

  Cleveland Clinic journal of medicine 20030901

• Ezetimibe for lowering blood cholesterol.

  Issues in emerging health technologies 20030901

• Pharmacology and therapeutics of ezetimibe (SCH 58235), a cholesterol-absorption inhibitor.

  Clinical therapeutics 20030901

• The place of ezetimibe in clinical practice.

  Hospital medicine (London, England : 1998) 20030801

• Achieving cholesterol goals. Current and future drug therapies.

  Postgraduate medicine 20030801

• Efficacy of simvastatin and ezetimibe in treating hypercholesterolemia.

  Journal of the American College of Cardiology 20030716

• Perspectives in cholesterol-lowering therapy: the role of ezetimibe, a new selective inhibitor of intestinal cholesterol absorption.

  Circulation 20030701

• Therapeutic approaches to dyslipidemia in diabetes mellitus and metabolic syndrome.

  Current opinion in cardiology 20030701

• Ezetimibe (Zetia): a new type of lipid-lowering agent.

  Proceedings (Baylor University. Medical Center) 20030701

• Combination lipid-lowering therapy in diabetes.

  Current diabetes reports 20030601

• Ezetimibe for management of hypercholesterolemia.

  The Annals of pharmacotherapy 20030601

• Cholesterol absorption inhibitors: defining new options in lipid management.

  Clinical cardiology 20030601

• Sterol absorption by the small intestine.

  Current opinion in lipidology 20030601

• Evaluation of the efficacy, safety, and tolerability of ezetimibe in primary hypercholesterolaemia: a pooled analysis from two controlled phase III clinical studies.

  International journal of clinical practice 20030601

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20030601

• [Coronary disease prevention: only the inhibition of inflammation is important. Why lower lipids, too?].

  MMW Fortschritte der Medizin 20030522

• Effect of ezetimibe coadministered with atorvastatin in 628 patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial.

  Circulation 20030520

• New lipid-lowering combo proves successful.

  Circulation 20030520

• [Controlling LDL cholesterol from 2 sides. 'I have never seen such low LDL values'].

  MMW Fortschritte der Medizin 20030515

• Familial hypercholesterolemia--improving treatment and meeting guidelines.

  International journal of cardiology 20030501

• Treating dyslipidemic patients with lipid-modifying and combination therapies.

  Pharmacotherapy 20030501

• Statins, super-statins and cholesterol absorption inhibitors.

  IDrugs : the investigational drugs journal 20030501

• 52nd Annual Scientific Session of the American College of Cardiology, Chicago, March 30-April 2, 2003.

  International journal of clinical practice 20030501

• Three new drugs for hyperlipidemia.

  Connecticut medicine 20030501

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20030501

• The future of lipid-lowering therapy: the big picture.

  The Netherlands journal of medicine 20030501

• Ezetimibe: a novel option for lowering cholesterol.

  Expert review of cardiovascular therapy 20030501

• Primary hypercholesterolemia: genetic causes and treatment of five monogenic disorders.

  Expert review of cardiovascular therapy 20030501

• Dyslipidemia treatment: current considerations and unmet needs.

  Expert review of cardiovascular therapy 20030501

• Synthesis of a biotin-tagged photoaffinity probe of 2-azetidinone cholesterol absorption inhibitors.

  Bioorganic & medicinal chemistry 20030417

• [Ezetimib as combination partner in hypercholesteremia. Lowering LDL beyond the effect of statins].

  MMW Fortschritte der Medizin 20030417

• New drug joins cholesterol-fighting arsenal.

  Mayo Clinic women's healthsource 20030401

• Combined lipid lowering drug therapy for the effective treatment of hypercholesterolaemia.

  European heart journal 20030401

• Efficacy and safety of ezetimibe coadministered with pravastatin in patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial.

  European heart journal 20030401

• Effects of ezetimibe, a new cholesterol absorption inhibitor, on plasma lipids in patients with primary hypercholesterolemia.

  European heart journal 20030401

• Ezetimibe potently inhibits cholesterol absorption but does not affect acute hepatic or intestinal cholesterol synthesis in rats.

  British journal of pharmacology 20030401

• Ezetimibe.

  Drugs of today (Barcelona, Spain : 1998) 20030401

• Three new drugs for hyperlipidemia.

  The Medical letter on drugs and therapeutics 20030303

• New lipid-modifying therapies.

  Expert opinion on investigational drugs 20030301

• New cholesterol-lowering drug makes its mark.

  Mayo Clinic health letter (English ed.) 20030301

• What future for combination therapies?

  International journal of clinical practice. Supplement 20030301

• Efficacy and safety of ezetimibe coadministered with lovastatin in primary hypercholesterolemia.

  The American journal of cardiology 20030215

• Fresh from the pipeline. Ezetimibe.

  Nature reviews. Drug discovery 20030201

• Beyond statins. New drugs can work with, or in place of, cholesterol-lowering statins.

  Harvard heart letter : from Harvard Medical School 20030201

• [Lowering cholesterol becomes easier. Combining instead of increasing dosage].

  MMW Fortschritte der Medizin 20030123

• Treating hypercholesterolemia: looking forward.

  Clinical cardiology 20030101

• Combination therapy for dyslipidemia.

  The Journal of the American Osteopathic Association 20030101

• A novel therapeutic approach to dyslipidemia.

  The Journal of the American Osteopathic Association 20030101

• [The best of clinical pharmacology in 2002].

  Archives des maladies du coeur et des vaisseaux 20030101

• The intestinal absorption of biliary and dietary cholesterol as a drug target for lowering the plasma cholesterol level.

  Preventive cardiology 20030101

• Zetia (ezetimibe).

  Congestive heart failure (Greenwich, Conn.) 20030101

• Ezetimibe added to ongoing statin therapy reduced LDL cholesterol in primary hypercholesterolemia.

  ACP journal club 20030101

• The need for a different cholesterol lowering drug.

  The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20030101

• Ezetimibe and cholesterol absorption.

  The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20030101

• Clinical use of ezetimibe.

  The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20030101

• Dietary cholesterol, cholesterol absorption, postprandial lipemia and atherosclerosis.

  The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20030101

• The pharmacokinetics of ezetimibe.

  The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20030101

• Overview of pharmacologic therapy for the treatment of dyslipidemia.

  Journal of managed care pharmacy : JMCP 20030101

• A novel therapeutic approach.

  Journal of managed care pharmacy : JMCP 20030101

• Combination therapy.

  Journal of managed care pharmacy : JMCP 20030101

• [Cardiovascular risk factor reduction. Cholesterol absorption inhibitors: a new action principle].

  Pharmazie in unserer Zeit 20030101

• Ezetimibe: a first-in-class, novel cholesterol absorption inhibitor.

  Cardiovascular drug reviews 20030101

• Ezetimibe.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20030101

• New concepts of mechanisms of intestinal cholesterol absorption.

  Annals of hepatology 20030101

• Ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia.

  Journal of the American College of Cardiology 20021218

• Low-density lipoprotein lowering therapy: an analysis of the options.

  Journal of the American College of Cardiology 20021218

• The future direction of cholesterol-lowering therapy.

  Current opinion in lipidology 20021201

• Atherosclerosis: cell biology and lipoproteins: cholesterol absorption inhibitors: gateway therapy for hypercholesterolaemia.

  Current opinion in lipidology 20021201

• Management of dyslipidemia in the high-risk patient.

  American heart journal 20021201

• [Ezetimib--the first selective cholesterol resorption inhibitors. Strengthening of statins].

  MMW Fortschritte der Medizin 20021128

• [Ezetimib plus statin combination. A strong duo].

  MMW Fortschritte der Medizin 20021128

• [Cholesterol resorption inhibition prevents high statin doses. Lipid lowering in double-pack].

  MMW Fortschritte der Medizin 20021128

• Combination therapy for combined dyslipidemia.

  The American journal of cardiology 20021120

• Use of combination therapy for dyslipidemia: a lipid clinic approach.

  The American journal of cardiology 20021120

• Combination therapy for dyslipidemia: safety and regulatory considerations.

  The American journal of cardiology 20021120

• Efficacy and safety of ezetimibe added to ongoing statin therapy for treatment of patients with primary hypercholesterolemia.

  The American journal of cardiology 20021115

• Efficacy and safety of a potent new selective cholesterol absorption inhibitor, ezetimibe, in patients with primary hypercholesterolemia.

  The American journal of cardiology 20021115

• [Improved antilipemic drug is approved. Cholesterol absorption is inhibited].

  MMW Fortschritte der Medizin 20021114

• Inhibition of cholesterol absorption by SCH 58053 in the mouse is not mediated via changes in the expression of mRNA for ABCA1, ABCG5, or ABCG8 in the enterocyte.

  Journal of lipid research 20021101

• Ezetimibe.

  Expert opinion on investigational drugs 20021101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20021101

• Inhibition of intestinal cholesterol absorption by ezetimibe in humans.

  Circulation 20021008

• Ezetimibe in hypercholesterolaemia.

  International journal of clinical practice 20021001

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20021001

• [Statins plus cholesterol resorption inhibitor. LDL goal values attainable].

  MMW Fortschritte der Medizin 20020919

• Pharmacodynamic interaction between the new selective cholesterol absorption inhibitor ezetimibe and simvastatin.

  British journal of clinical pharmacology 20020901

• Promising therapies for cholesterol reduction.

  Managed care (Langhorne, Pa.) 20020901

• [Antilipemic agents in combined therapy].

  Orvosi hetilap 20020825

• New cholesterol guidelines, new treatment challenges.

  Pharmacotherapy 20020701

• [Ezetimib. A new cholesterol absorption inhibitor].

  Medizinische Monatsschrift fur Pharmazeuten 20020701

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• Molecule of the month. Ezetimibe.

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• The cholesterol absorption inhibitor, ezetimibe, decreases diet-induced hypercholesterolemia in monkeys.

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