1633-83-6 | 1,4-Butane sultone

Packsize	Purity	Availability	Price	Discounted Price
25g	97%	in stock	$13.00	$9.00
100g	97%	in stock	$20.00	$14.00
500g	97%	in stock	$61.00	$43.00
1000g	97%	in stock	$74.00	$52.00

Description

• Catalog Number: AA85346
• Chemical Name: 1,4-Butane sultone
• CAS Number: 1633-83-6
• Molecular Formula: C4H8O3S
• Molecular Weight: 136.1695
• MDL Number: MFCD00006584
• SMILES: O=S1(=O)CCCCO1
• NSC Number: 71999

Computed Properties

• Complexity: 153
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 3
• XLogP3: 0.1

Upstream Synthesis Route

1,4-Butane sultone, also known as tetrahydrothiophene 1,1-dioxide, plays a crucial role in chemical synthesis due to its unique properties and versatile applications. This cyclic sulfonate compound is widely used as a bifunctional alkylating agent in organic chemistry. It serves as a sulfonating agent, alkylating agent, and a precursor in various synthetic reactions.In chemical synthesis, 1,4-Butane sultone is utilized to introduce sulfonate groups into organic molecules, enabling the formation of sulfonate esters and sulfonamides. These sulfonate groups can serve as protecting groups for sensitive functional groups in complex molecule synthesis or as reactive intermediates in further transformations. Additionally, 1,4-Butane sultone can act as an alkylating agent, introducing alkyl chains onto nucleophilic centers in organic molecules. This versatile reactivity makes it a valuable tool in the synthesis of specialty chemicals, pharmaceuticals, and agrochemicals.Furthermore, 1,4-Butane sultone is commonly utilized in the modification of biomolecules such as proteins and peptides. Its ability to selectively alkylate certain amino acid residues in proteins makes it useful for protein modification and bioconjugation reactions. By selectively introducing sulfonate groups onto specific amino acids, researchers can alter the properties and functions of proteins for various biotechnological applications.Overall, the versatile application of 1,4-Butane sultone in chemical synthesis highlights its importance as a key building block for the construction of complex organic molecules and the modification of biomolecules for scientific research and industrial purposes.

Literature

• Silica-supported sulfonic acid-functionalized ionic liquid coated with [bmim][PF6] as a scavenger for the synthesis of amides.

  Molecular diversity 20110201

• A novel supramolecular organogel nanotubular template approach for conducting nanomaterials.

  The journal of physical chemistry. B 20100121

• Self-assembled cylindrical and vesicular molecular templates for polyaniline nanofibers and nanotapes.

  The journal of physical chemistry. B 20090827

• Masked imidazolyl-dipyrromethanes in the synthesis of imidazole-substituted porphyrins.

  The Journal of organic chemistry 20061110

• Quantitative structure-activity relationship modeling of acute toxicity of quaternary alkylammonium sulfobetaines to Daphnia magna.

  Environmental toxicology and chemistry 20040901