16816-67-4 | D-Pantethine syrup

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$25.00	$18.00
5g	95%	in stock	$53.00	$38.00
10g	95%	in stock	$74.00	$52.00
25g	95%	in stock	$163.00	$114.00
100g	95%	in stock	$473.00	$331.00
1kg	95%	in stock	$3,762.00	$2,633.00

Description

• Catalog Number: AB50456
• Chemical Name: D-Pantethine syrup
• CAS Number: 16816-67-4
• Molecular Formula: C22H42N4O8S2
• Molecular Weight: 554.7209
• MDL Number: MFCD07357235
• SMILES: OCC([C@H](C(=O)NCCC(=O)NCCSSCCNC(=O)CCNC(=O)[C@@H](C(CO)(C)C)O)O)(C)C

Computed Properties

• Complexity: 652
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 2
• Heavy Atom Count: 36
• Hydrogen Bond Acceptor Count: 10
• Hydrogen Bond Donor Count: 8
• Rotatable Bond Count: 19
• XLogP3: -2.2

Literature

• Pantethine, a derivative of vitamin B5, favorably alters total, LDL and non-HDL cholesterol in low to moderate cardiovascular risk subjects eligible for statin therapy: a triple-blinded placebo and diet-controlled investigation.

  Vascular health and risk management 20140101

• The role of nutraceutical supplements in the treatment of dyslipidemia.

  Journal of clinical hypertension (Greenwich, Conn.) 20120201

• Impaired Coenzyme A metabolism affects histone and tubulin acetylation in Drosophila and human cell models of pantothenate kinase associated neurodegeneration.

  EMBO molecular medicine 20111201

• Pantethine, a derivative of vitamin B(5) used as a nutritional supplement, favorably alters low-density lipoprotein cholesterol metabolism in low- to moderate-cardiovascular risk North American subjects: a triple-blinded placebo and diet-controlled investigation.

  Nutrition research (New York, N.Y.) 20110801

• Comparison of the effects of pantethine and fursultiamine on plasma gastrointestinal peptide levels in healthy volunteers.

  Biological & pharmaceutical bulletin 20110101

• Pantethine. Monograph.

  Alternative medicine review : a journal of clinical therapeutic 20100901

• Enhancement of L-3-hydroxybutyryl-CoA dehydrogenase activity and circulating ketone body levels by pantethine. Relevance to dopaminergic injury.

  BMC neuroscience 20100101

• Current medical aspects of pantethine.

  Ideggyogyaszati szemle 20090730

• Topical apolipoprotein A-1 may have a beneficial effect on the corneal epithelium in a mouse model of dry eye: a pilot study.

  Eye & contact lens 20080901

• An Arabidopsis mutant impaired in coenzyme A biosynthesis is sugar dependent for seedling establishment.

  Plant physiology 20060301

• Dietary and nutraceutical options for managing the hypertriglyceridemic patient.

  Progress in cardiovascular nursing 20060101

• Inhibition of acetyl-CoA carboxylase by cystamine may mediate the hypotriglyceridemic activity of pantethine.

  Medical hypotheses 20010301

• Can drugs or micronutrients prevent cataract?

  Drugs & aging 20010101