-
Effect of oestrogen receptors on brain NMDA receptors of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice.
Journal of neuroendocrinology 20121101
-
Ifenprodil, a NR2B-selective antagonist of NMDA receptor, inhibits reverse Na+/Ca2+ exchanger in neurons.
Neuropharmacology 20121101
-
Involvement of the anterior cingulate cortex in formation, consolidation, and reconsolidation of recent and remote contextual fear memory.
Learning & memory (Cold Spring Harbor, N.Y.) 20120914
-
NMDARs mediate the role of monoamine oxidase A in pathological aggression.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20120620
-
NMDA receptor mediated phosphorylation of GluR1 subunits contributes to the appearance of calcium-permeable AMPA receptors after mechanical stretch injury.
Neurobiology of disease 20120601
-
Investigation of the antidyskinetic site of action of metabotropic and ionotropic glutamate receptor antagonists. Intracerebral infusions in 6-hydroxydopamine-lesioned rats with levodopa-induced dyskinesia.
European journal of pharmacology 20120515
-
Hippocampus versus entorhinal cortex decoupling by an NR2 subunit-specific block of NMDA receptors in a rat in vitro model of temporal lobe epilepsy.
Epilepsia 20120501
-
Reduction of inflammatory pain in female rats after NR2B NMDA cortical antagonism.
Psicothema 20120501
-
Effect of NMDA NR2B antagonist on neuropathic pain in two spinal cord injury models.
Pain 20120501
-
Role of GluN2A and GluN2B subunits in the formation of filopodia and secondary dendrites in cultured hippocampal neurons.
Naunyn-Schmiedeberg's archives of pharmacology 20120201
-
Isoflurane/nitrous oxide anesthesia induces increases in NMDA receptor subunit NR2B protein expression in the aged rat brain.
Brain research 20120111
-
Inhibition of Ca2+/calmodulin-dependent protein kinase II reverses oxaliplatin-induced mechanical allodynia in rats.
Molecular pain 20120101
-
Genetic, pharmacological and lesion analyses reveal a selective role for corticohippocampal GLUN2B in a novel repeated swim stress paradigm.
Neuroscience 20111013
-
Neuronal NR2B-containing NMDA receptor mediates spinal astrocytic c-Jun N-terminal kinase activation in a rat model of neuropathic pain.
Brain, behavior, and immunity 20111001
-
Blockade of NMDA receptors 2A subunit in the dorsal striatum impairs the learning of a complex motor skill.
Behavioral neuroscience 20111001
-
Kalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and function.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20110831
-
Blockade of NMDA GluN2B receptors selectively impairs behavioral flexibility but not initial discrimination learning.
Psychopharmacology 20110801
-
Involvement of synaptic NR2B-containing NMDA receptors in long-term depression induction in the young rat visual cortex in vitro.
The Chinese journal of physiology 20110630
-
Peripheral administration of NR2 antagonists attenuates orofacial formalin-induced nociceptive behavior in rats.
Progress in neuro-psychopharmacology & biological psychiatry 20110601
-
A silent synapse-based mechanism for cocaine-induced locomotor sensitization.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20110601
-
Dopamine induces a GluN2A-dependent form of long-term depression of NMDA synaptic responses in the nucleus accumbens.
Neuropharmacology 20110501
-
Therapeutic significance of NR2B-containing NMDA receptors and mGluR5 metabotropic glutamate receptors in mediating the synaptotoxic effects of β-amyloid oligomers on long-term potentiation (LTP) in murine hippocampal slices.
Neuropharmacology 20110501
-
NR2B subunit blockade does not affect motor symptoms induced by 3-nitropropionic acid.
Neurological research 20110501
-
Glutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure.
Biological psychiatry 20110415
-
The effects of NMDA receptor antagonists on attentional set-shifting task performance in mice.
Psychopharmacology 20110401
-
NR2B subunit-specific NMDA antagonist Ro25-6981 inhibits the expression of conditioned fear: a comparison with the NMDA antagonist MK-801 and fluoxetine.
Behavioural pharmacology 20110401
-
Nickel modulates the electrical activity of cultured cortical neurons through a specific effect on N-methyl-D-aspartate receptor channels.
Neuroscience 20110317
-
Cyclic adenosine monophosphate-independent tyrosine phosphorylation of NR2B mediates cocaine-induced extracellular signal-regulated kinase activation.
Biological psychiatry 20110201
-
[Effects of the neurogenesis stimulator Ro 25-6981 upon formation of spatial skill in adult rats depend on the term of its administration and the animals' ability to learn].
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20110201
-
An examination of NMDA receptor contribution to conditioned responding evoked by the conditional stimulus effects of nicotine.
Psychopharmacology 20110101
-
Involvement of spinal NR2B-containing NMDA receptors in oxaliplatin-induced mechanical allodynia in rats.
Molecular pain 20110101
-
Intracisternal administration of NR2 subunit antagonists attenuates the nociceptive behavior and p-p38 MAPK expression produced by compression of the trigeminal nerve root.
Molecular pain 20110101
-
Lack of efficacy of NMDA receptor-NR2B selective antagonists in the R6/2 model of Huntington disease.
Experimental neurology 20101001
-
Identification of a novel NR2B-selective NMDA receptor antagonist using a virtual screening approach.
Bioorganic & medicinal chemistry letters 20100915
-
mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists.
Science (New York, N.Y.) 20100820
-
Long-lasting adaptations of the NR2B-containing NMDA receptors in the dorsomedial striatum play a crucial role in alcohol consumption and relapse.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20100728
-
Inverse relationship between seizure expression and extrasynaptic NMDAR function following chronic NMDAR inhibition.
Epilepsia 20100701
-
Stoichiometry of N-methyl-D-aspartate receptors within the suprachiasmatic nucleus.
Journal of neurophysiology 20100601
-
Contribution of the spinal cord BDNF to the development of neuropathic pain by activation of the NR2B-containing NMDA receptors in rats with spinal nerve ligation.
Experimental neurology 20100401
-
Effects of agents targeting glutamatergic systems on marble-burying behavior.
Neuroscience letters 20100303
-
NMDA NR2B subtype-selective receptor antagonists fail to antagonize electrically-precipitated seizures and elicit popping in mice.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20100301
-
Effects of acute stress and GluN2B-containing NMDA receptor antagonism on object and object-place recognition memory.
Neurobiology of learning and memory 20100201
-
Intracisternal administration of NR2 antagonists attenuates facial formalin-induced nociceptive behavior in rats.
Journal of orofacial pain 20100101
-
Postsynaptic response to stimulation of the Schaffer collaterals with properties similar to those of synaptosomal aspartate release.
Brain research 20091027
-
NR2A-containing NMDA receptors are required for L-LTP induction and depotentiation in CA1 region of hippocampal slices.
The European journal of neuroscience 20090601
-
A novel protein complex in membrane rafts linking the NR2B glutamate receptor and autophagy is disrupted following traumatic brain injury.
Journal of neurotrauma 20090501
-
Platelet-derived growth factor selectively inhibits NR2B-containing N-methyl-D-aspartate receptors in CA1 hippocampal neurons.
The Journal of biological chemistry 20090320
-
Late phase of long-term potentiation induced by co-application of N-methyl-d-aspartic acid and the antagonist of NR2B-containing N-methyl-d-aspartic acid receptors in rat hippocampus.
Neuroscience 20090303
-
Development of 3-substituted-1H-indole derivatives as NR2B/NMDA receptor antagonists.
Bioorganic & medicinal chemistry 20090215
-
Role of the spinal cord NR2B-containing NMDA receptors in the development of neuropathic pain.
Experimental neurology 20090201
-
Fear memory impairing effects of systemic treatment with the NMDA NR2B subunit antagonist, Ro 25-6981, in mice: attenuation with ageing.
Pharmacology, biochemistry, and behavior 20090101
-
A role of periaqueductal grey NR2B-containing NMDA receptor in mediating persistent inflammatory pain.
Molecular pain 20090101
-
D1/5 receptor-mediated enhancement of LTP requires PKA, Src family kinases, and NR2B-containing NMDARs.
Neuropharmacology 20081001
-
Differential effect of NR2A and NR2B subunit selective NMDA receptor antagonists on striato-pallidal neurons: relationship to motor response in the 6-hydroxydopamine model of parkinsonism.
Journal of neurochemistry 20080701
-
Cerebellar granule cells cultured from adolescent rats express functional NMDA receptors: an in vitro model for studying the developing cerebellum.
Journal of neurochemistry 20080701
-
D-serine augments NMDA-NR2B receptor-dependent hippocampal long-term depression and spatial reversal learning.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080401
-
Spinal cord long-term potentiation is attenuated by the NMDA-2B receptor antagonist Ro 25-6981.
Acta physiologica (Oxford, England) 20080301
-
Tonic facilitation of glutamate release by glycine binding sites on presynaptic NR2B-containing NMDA autoreceptors in the rat visual cortex.
Neuroscience letters 20080227
-
Intrathecal high-dose histamine induces spinally-mediated nociceptive behavioral responses through a polyamine site of NMDA receptors.
European journal of pharmacology 20080226
-
Brain-derived neurotrophic factor activation of extracellular signal-regulated kinase is autonomous from the dominant extrasynaptic NMDA receptor extracellular signal-regulated kinase shutoff pathway.
Neuroscience 20080124
-
Effects of pan- and subtype-selective N-methyl-D-aspartate receptor antagonists on cortical spreading depression in the rat: therapeutic potential for migraine.
The Journal of pharmacology and experimental therapeutics 20070501
-
Selective NR1/2B N-methyl-D-aspartate receptor antagonists among indole-2-carboxamides and benzimidazole-2-carboxamides.
Journal of medicinal chemistry 20070308
-
Contribution of NMDA receptor NR2B subunit to synaptic plasticity during associative learning in behaving rats.
The European journal of neuroscience 20070201
-
Activation of NR2B-containing NMDA receptors is not required for NMDA receptor-dependent long-term depression.
Neuropharmacology 20070101
-
Differential roles of NR2A and NR2B-containing NMDA receptors in LTP and LTD in the CA1 region of two-week old rat hippocampus.
Neuropharmacology 20070101
-
NR2B antagonists restrict spatiotemporal spread of activity in a rat model of cortical dysplasia.
Epilepsy research 20061201
-
N-methyl-D-aspartate receptor-dependent long-term potentiation in CA1 region affects synaptic expression of glutamate receptor subunits and associated proteins in the whole hippocampus.
Neuroscience 20060901
-
Benzimidazole-2-carboxamides as novel NR2B selective NMDA receptor antagonists.
Bioorganic & medicinal chemistry letters 20060901
-
NR2B-containing N-methyl-D-aspartate subtype glutamate receptors regulate the acute stress effect on hippocampal long-term potentiation/long-term depression in vivo.
Neuroreport 20060821
-
Estradiol-induced increase in the magnitude of long-term potentiation is prevented by blocking NR2B-containing receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20060816
-
An animal model of chronic inflammatory pain: pharmacological and temporal differentiation from acute models.
European journal of pain (London, England) 20060801
-
Effects of N-methyl-D-aspartate receptor antagonism on neuroleptic-induced orofacial dyskinesias.
Psychopharmacology 20060401
-
Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20060315
-
Glutamate-based therapeutic approaches: NR2B receptor antagonists.
Current opinion in pharmacology 20060201
-
Novel blockade of protein kinase A-mediated phosphorylation of AMPA receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20060125
-
Tonic facilitation of glutamate release by presynaptic NR2B-containing NMDA receptors is increased in the entorhinal cortex of chronically epileptic rats.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20060111
-
Role of neuronal NR2B subunit-containing NMDA receptor-mediated Ca2+ influx and astrocytic activation in cultured mouse cortical neurons and astrocytes.
Synapse (New York, N.Y.) 20060101
-
Contribution of NR2A and NR2B NMDA subunits to bidirectional synaptic plasticity in the hippocampus in vivo.
Hippocampus 20060101
-
Stress evoked by opiate withdrawal facilitates hippocampal LTP in vivo.
Hippocampus 20060101
-
Roles of NMDA NR2B subtype receptor in prefrontal long-term potentiation and contextual fear memory.
Neuron 20050915
-
Functional roles of NMDA receptor NR2A and NR2B subunits in the acute intoxicating effects of ethanol in mice.
Synapse (New York, N.Y.) 20050615
-
Selective subunit antagonists suggest an inhibitory relationship between NR2B and NR2A-subunit containing N-methyl-D: -aspartate receptors in hippocampal slices.
Experimental brain research 20050401
-
BDNF enhancement of postsynaptic NMDA receptors is blocked by ethanol.
Synapse (New York, N.Y.) 20050101
-
The NR2B-selective N-methyl-D-aspartate receptor antagonist Ro 25-6981 [(+/-)-(R*,S*)-alpha-(4-hydroxyphenyl)-beta-methyl-4-(phenylmethyl)-1-piperidine propanol] potentiates the effect of nicotine on locomotor activity and dopamine release in the nucleus accumbens.
The Journal of pharmacology and experimental therapeutics 20041101
-
Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908
-
Oxamides as novel NR2B selective NMDA receptor antagonists.
Bioorganic & medicinal chemistry letters 20040802
-
Modulation of morphine analgesia by site-specific N-methyl-D-aspartate receptor antagonists: dependence on sex, site of antagonism, morphine dose, and time.
Pain 20040601
-
Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity.
Science (New York, N.Y.) 20040514
-
Antiparkinsonian activity of Ro 25-6981, a NR2B subunit specific NMDA receptor antagonist, in animal models of Parkinson's disease.
Experimental neurology 20040501
-
The NMDA receptor NR2B subunit: a valid therapeutic target for multiple CNS pathologies.
Current medicinal chemistry 20040201
-
Identification of critical residues in the amino terminal domain of the human NR2B subunit involved in the RO 25-6981 binding pocket.
The Journal of pharmacology and experimental therapeutics 20031201
-
Indole-2-carboxamides as novel NR2B selective NMDA receptor antagonists.
Bioorganic & medicinal chemistry letters 20031103
-
Asymmetrical allocation of NMDA receptor epsilon2 subunits in hippocampal circuitry.
Science (New York, N.Y.) 20030509
-
Role of the NMDA receptor NR2B subunit in the discriminative stimulus effects of ketamine.
Behavioural pharmacology 20030501
-
2-(3,4-Dihydro-1H-isoquinolin-2yl)-pyridines as a novel class of NR1/2B subtype selective NMDA receptor antagonists.
Bioorganic & medicinal chemistry letters 20030310
-
Novel N1-(benzyl)cinnamamidine derived NR2B subtype-selective NMDA receptor antagonists.
Bioorganic & medicinal chemistry letters 20030224
-
The NMDA receptor NR2B subtype selective antagonist Ro 25-6981 aggravates paroxysmal dyskinesia in the dt(sz) mutant.
European journal of pharmacology 20030101
-
Blockade of NMDA receptor subtype NR2B prevents seizures but not apoptosis of dentate gyrus neurons in bacterial meningitis in infant rats.
BMC neuroscience 20030101
-
Role of NR2B-containing N-methyl-D-aspartate receptors in haloperidol-induced c-Fos expression in the striatum and nucleus accumbens.
Neuroscience 20030101
-
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
The Journal of biological chemistry 20020419
-
Discovery of (R)-1-[2-hydroxy-3-(4-hydroxy-phenyl)-propyl]-4-(4-methyl-benzyl)-piperidin-4-ol: a novel NR1/2B subtype selective NMDA receptor antagonist.
Bioorganic & medicinal chemistry letters 20010820
-
Estrogen-like activity of tamoxifen and raloxifene on NMDA receptor binding and expression of its subunits in rat brain.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010801
-
NMDA receptor antagonists do not block the development of sensitization of catalepsy, but make its expression state-dependent.
Behavioural pharmacology 20010401
-
Pharmacological characterization of interactions of RO 25-6981 with the NR2B (epsilon2) subunit.
European journal of pharmacology 20010330