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Rhodium(II) catalyzed diastereoselective reactions of diazoacetamides with isatins: an efficient approach to 3-hydroxy-3,3'-bioxindoles.
Organic & biomolecular chemistry 20121128
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Enantioselective construction of multifunctionalized spirocyclohexaneoxindoles through organocatalytic Michael-Aldol cyclization of isatin derived alkenes with linear dialdehydes.
Organic & biomolecular chemistry 20121128
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Aza-oxindole synthesis via base promoted Truce-Smiles rearrangement.
Chemical communications (Cambridge, England) 20121118
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Enantioselective Michael addition of 3-aryloxindoles to a vinyl bisphosphonate ester catalyzed by a cinchona alkaloid derived thiourea catalyst.
Organic & biomolecular chemistry 20121021
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Synthesis of oxindolyl pyrazolines and 3-amino oxindole building blocks via a nitrile imine [3 + 2] cycloaddition strategy.
Organic letters 20121019
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Facile synthesis of dispirooxindole-fused heterocycles via domino 1,4-dipolar addition and Diels-Alder reaction of in situ generated Huisgen 1,4-dipoles.
Organic letters 20121019
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Discovery of a novel class of exquisitely selective mesenchymal-epithelial transition factor (c-MET) protein kinase inhibitors and identification of the clinical candidate 2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol (PF-04217903) for the treatment of cancer.
Journal of medicinal chemistry 20120927
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Spiro-fused pyrrolidine, piperidine, and oxindole scaffolds from lactams.
Organic letters 20120921
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Application of the systems chemistry approach on the ammonolysis of 1-ethoxycarbonyl- and 1-phenoxycarbonyl-3-(2-thienyl)oxindoles. A method to predict reactivity.
The Journal of organic chemistry 20120907
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Synthesis and biological evaluation of novel oxindole derivatives for imaging neurofibrillary tangles in Alzheimer's disease.
Bioorganic & medicinal chemistry letters 20120901
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Copper-catalyzed domino coupling reaction: an efficient method to synthesize oxindoles.
Organic & biomolecular chemistry 20120821
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Enantioselective construction of 3-hydroxy oxindoles via decarboxylative addition of β-ketoacids to isatins.
Organic letters 20120803
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Synthesis, characterization and in vitro antimicrobial evaluation of new compounds incorporating oxindole nucleus.
Journal of enzyme inhibition and medicinal chemistry 20120801
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Enamino-oxindole HIV protease inhibitors.
Bioorganic & medicinal chemistry letters 20120801
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Multicomponent reaction to construct spirocyclic oxindoles with a Michael (triple Michael)/cyclization cascade sequence as the key step.
Chemistry (Weinheim an der Bergstrasse, Germany) 20120727
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Strategies for the enantioselective synthesis of spirooxindoles.
Organic & biomolecular chemistry 20120721
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Enantioselective synthesis of 3,3'-dihydropyrryl-spirooxindoles via an organocatalytic three-component reaction.
Organic & biomolecular chemistry 20120721
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Organocatalytic enantioselective stereoablative hydroxylation of 3-halooxindoles: an effective method for the construction of enantioenriched 3-substituted 3-hydroxy-2-oxindoles.
Chemistry (Weinheim an der Bergstrasse, Germany) 20120716
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Catalytic asymmetric synthesis of spirooxindoles by a mannich-type reaction of isothiocyanato oxindoles.
Angewandte Chemie (International ed. in English) 20120709
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Diastereodivergent synthesis of 3-spirocyclopropyl-2-oxindoles through direct enantioselective cyclopropanation of oxindoles.
Chemistry (Weinheim an der Bergstrasse, Germany) 20120702
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Catalytic asymmetric exo'-selective [3+2] cycloaddition for constructing stereochemically diversified spiro[pyrrolidin-3,3'-oxindole]s.
Chemistry (Weinheim an der Bergstrasse, Germany) 20120702
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Enantioselective Michael addition of 3-aryl-substituted oxindoles to methyl vinyl ketone catalyzed by a binaphthyl-modified bifunctional organocatalyst.
Molecules (Basel, Switzerland) 20120618
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Catalytic asymmetric sulfenylation of unprotected 3-substituted oxindoles.
Organic letters 20120601
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Bicyclic guanidine-catalyzed asymmetric Michael additions of 3-benzyl-substituted oxindoles to N-maleimides.
Chemical communications (Cambridge, England) 20120525
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Organocatalytic asymmetric conjugate addition of 3-monosubstituted oxindoles to (E)-1,4-diaryl-2-buten-1,4-diones: a strategy for the indirect enantioselective furanylation and pyrrolylation of 3-alkyloxindoles.
Chemistry (Weinheim an der Bergstrasse, Germany) 20120521
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Phenyliodine bis(trifluoroacetate)-mediated oxidative C-C bond formation: synthesis of 3-hydroxy-2-oxindoles and spirooxindoles from anilides.
Organic letters 20120504
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Access to spirocyclic oxindoles via N-heterocyclic carbene-catalyzed reactions of enals and oxindole-derived α,β-unsaturated imines.
Organic letters 20120504
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A novel class of sugar-based ether-linked-dispirooxindolo-pyrrolidines/pyrrolizidines through [3+2]-cycloaddition of azomethine ylides.
Carbohydrate research 20120501
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Intramolecular 1,3-dipolar cycloaddition reactions in the synthesis of complex annelated quinolines, α-carbolines and coumarins.
Molecular diversity 20120501
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Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity.
European journal of medicinal chemistry 20120501
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A catalytic metal-free Ritter reaction to 3-substituted 3-aminooxindoles.
Organic & biomolecular chemistry 20120428
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Ionic nucleophilic catalysis of chiral ammonium betaines for highly stereoselective aldol reaction from oxindole-derived vinylic carbonates.
Journal of the American Chemical Society 20120425
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Catalytic stereoselective synthesis of diverse oxindoles and spirooxindoles from isatins.
ACS combinatorial science 20120409
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Zinc-mediated diastereoselective synthesis of 3-amino oxindoles by addition of methyl and terminal alkynes to N-tert-butanesulfinyl ketimines.
The Journal of organic chemistry 20120406
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Ring enlargement versus selenoetherification on the reaction of allenyl oxindoles with selenenylating reagents.
The Journal of organic chemistry 20120406
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Aza-oxindole synthesis by oxidative coupling of C(sp2)-H and C(sp3)-H centers.
Chemical communications (Cambridge, England) 20120325
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Palladium-catalyzed amidation by chemoselective C(sp3)-H activation: concise route to oxindoles using a carbamoyl chloride precursor.
Angewandte Chemie (International ed. in English) 20120312
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Asymmetric synthesis of allenyl oxindoles and spirooxindoles by a catalytic enantioselective Saucy-Marbet Claisen rearrangement.
Angewandte Chemie (International ed. in English) 20120305
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N-Heterocyclic carbene-catalyzed three-component domino reaction of alkynyl aldehydes with oxindoles.
Organic letters 20120302
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Efficient synthesis of multicyclic spirooxindoles via a cascade Michael/Michael/oxa-Michael reaction of curcumins and isatylidene malononitriles.
Organic & biomolecular chemistry 20120227
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Asymmetric assembly of 2-oxindole and α-angelica lactone units to construct vicinal quaternary chiral centers.
Chemical communications (Cambridge, England) 20120227
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Development of a nano-electrospray MSn method for the analysis of serotonin and related compounds in urine using a LTQ-orbitrap mass spectrometer.
Talanta 20120215
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Facile synthesis of azaarene-substituted 3-hydroxy-2-oxindoles via Brønsted acid catalyzed sp3 C-H functionalization.
Organic letters 20120203
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The Arabidopsis concentration-dependent influx/efflux transporter ABCB4 regulates cellular auxin levels in the root epidermis.
The Plant journal : for cell and molecular biology 20120201
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Spiro[pyrrolidine-2,3'-oxindole] derivatives synthesized by novel regionselective 1,3-dipolar cycloadditions.
Molecular diversity 20120201
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Building addressable libraries: amino acid derived fluorescent linkers.
Langmuir : the ACS journal of surfaces and colloids 20120124
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Core-structure-oriented asymmetric organocatalytic substitution of 3-hydroxyoxindoles: application in the enantioselective total synthesis of (+)-folicanthine.
Angewandte Chemie (International ed. in English) 20120123
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Dioxindole in asymmetric catalytic synthesis: routes to enantioenriched 3-substituted 3-hydroxyoxindoles and the preparation of maremycin A.
Angewandte Chemie (International ed. in English) 20120123
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Synthesis of oxindoles via visible light photoredox catalysis.
Organic & biomolecular chemistry 20120121
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Highly efficient and stereoselective construction of dispiro-[oxazolidine-2-thione]bisoxindoles and dispiro[imidazolidine-2-thione]bisoxindoles.
Organic letters 20120120
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Asymmetric hydroxyamination of oxindoles catalyzed by chiral bifunctional tertiary amine thiourea: construction of 3-amino-2-oxindoles with quaternary stereocenters.
Organic & biomolecular chemistry 20120114
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Enantioselective organocatalytic oxyamination of unprotected 3-substituted oxindoles.
Organic & biomolecular chemistry 20120114
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Synthesis of highly functionalized chiral 3,3'-disubstituted oxindoles via an organocatalytic enantioselective Michael addition of nitroalkanes to indolylidenecyanoacetates.
Organic letters 20120106
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HPLC analysis of oxindole alkaloids in Uncaria tomentosa: sample preparation and analysis optimisation by factorial design.
Phytochemical analysis : PCA 20120101
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Comparative study of fourteen alkaloids from Uncaria rhynchophylla hooks and leaves using HPLC-diode array detection-atmospheric pressure chemical ionization/MS method.
Chemical & pharmaceutical bulletin 20120101
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Overdiagnosis of a typical carcinoid tumor as an adenocarcinoma of the lung: a case report and review of the literature.
World journal of surgical oncology 20120101
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Synthesis of a dual functional anti-MDR tumor agent PH II-7 with elucidations of anti-tumor effects and mechanisms.
PloS one 20120101
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Ethylene in organic synthesis: a new route to anticholenergic pyrrolidinoindolines, and other molecules with all carbon-quaternary centers via asymmetric hydrovinylation.
Organic letters 20111216
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Catalytic asymmetric construction of spirocyclopentaneoxindoles by a combined Ru-catalyzed cross-metathesis/double Michael addition sequence.
Organic letters 20111202
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Highly enantioselective one-pot synthesis of spirocyclopentaneoxindoles containing the oxime group by organocatalyzed Michael addition/ISOC/fragmentation sequence.
Organic letters 20111202
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Synthesis and biological evaluation of 2-indolinone derivatives as potential antitumor agents.
European journal of medicinal chemistry 20111201
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Binding of oxindole-Schiff base copper(II) complexes to DNA and its modulation by the ligand.
Journal of inorganic biochemistry 20111201
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Pericyclic cascade with chirality transfer: reaction pathway and origin of enantioselectivity of the hetero-Claisen approach to oxindoles.
Angewandte Chemie (International ed. in English) 20111125
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Synthesis and stereochemical determination of complestatin A and B (neuroprotectin A and B).
Journal of the American Chemical Society 20111116
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Polarized IR spectra of the hydrogen bond in two different oxindole polymorphs with cyclic dimers in their lattices.
The journal of physical chemistry. A 20111110
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Development of an LC-MS/MS method for the analysis of serotonin and related compounds in urine and the identification of a potential biomarker for attention deficit hyperactivity/hyperkinetic disorder.
Analytical and bioanalytical chemistry 20111101
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Trifluoroacetic acid-promoted synthesis of 3-hydroxy, 3-amino and spirooxindoles from α-keto-N-anilides.
Organic letters 20111021
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Diastereo- and enantioselective conjugate addition of 3-substituted oxindoles to nitroolefins catalyzed by a chiral Ni(OAc)2-diamine complex under mild conditions.
Organic letters 20111007
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Receptor-based QSAR study for a series of 3,3-disubstituted-5-aryl oxindoles and 6-aryl benzimidazol-2-ones derivatives as progesterone receptor inhibitors.
SAR and QSAR in environmental research 20111001
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Catalytic enantioselective total synthesis of hodgkinsine B.
Angewandte Chemie (International ed. in English) 20110919
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Enantioselective Michael/cyclization reaction sequence: scaffold-inspired synthesis of spirooxindoles with multiple stereocenters.
Angewandte Chemie (International ed. in English) 20110919
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Chiral counteranion synergistic organocatalysis under high temperature: efficient construction of optically pure spiro[cyclohexanone-oxindole] backbone.
Organic letters 20110916
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Ultrasound promoted clay catalyzed efficient and one pot synthesis of substituted oxindoles.
Ultrasonics sonochemistry 20110901
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Ligand polarizability contributes to tau fibril binding affinity.
Bioorganic & medicinal chemistry 20110901
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Asymmetric decarboxylative allylation of oxindoles.
Organic letters 20110819
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Addition of TMSCN to chiral ketimines derived from isatin. Synthesis of an oxindole-based peptidomimetic and a bioactive spirohydantoin.
Organic & biomolecular chemistry 20110807
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Rauniticine-allo-oxindole B and rauniticinic-allo acid B, new heteroyohimbine-type oxindole alkaloids from the stems of Malaysian Uncaria longiflora var. pteropoda.
Molecules (Basel, Switzerland) 20110804
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Continuous-flow synthesis of 3,3-disubstituted oxindoles by a palladium-catalyzed α-arylation/alkylation sequence.
Angewandte Chemie (International ed. in English) 20110704
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Syntheses of spirocyclic oxindole-butenolides by using three-component cycloadditions of isocyanides, allenoates, and isatins.
Chemistry (Weinheim an der Bergstrasse, Germany) 20110627
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Highly enantioselective Michael addition of 2-oxindoles to vinyl selenone in RTILs catalyzed by a Cinchona alkaloid-based thiourea.
Chemical communications (Cambridge, England) 20110621
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Directed oxidative cyclizations to C2- or C4-positions of indole: efficient construction of the bicyclo[4.3.1]decane core of welwitindolinones.
Organic letters 20110617
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Discovery of XEN907, a spirooxindole blocker of NaV1.7 for the treatment of pain.
Bioorganic & medicinal chemistry letters 20110615
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Potent and selective oxindole-based vasopressin 1b receptor antagonists with improved pharmacokinetic properties.
Bioorganic & medicinal chemistry letters 20110615
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Electron density of two bioactive oligocyclic indole and oxindole derivatives obtained from low-order X-ray data and invariom application.
Chemistry, an Asian journal 20110606
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Synthesis and anticancer activity of oxindole derived imidazo[1,5-a]pyrazines.
European journal of medicinal chemistry 20110601
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Construction of bispirooxindoles containing three quaternary stereocentres in a cascade using a single multifunctional organocatalyst.
Nature chemistry 20110601
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Amino-indanol-catalyzed asymmetric Michael additions of oxindoles to protected 2-amino-1-nitroethenes for the synthesis of 3,3'-disubstituted oxindoles bearing α,β-diamino functionality.
The Journal of organic chemistry 20110520
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Iodo-carbocyclization of electron-deficient alkenes: synthesis of oxindoles and spirooxindoles.
Organic letters 20110506
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The neurotransmitter serotonin interrupts α-synuclein amyloid maturation.
Biochimica et biophysica acta 20110501
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Network modeling of MDM2 inhibitor-oxaliplatin combination reveals biological synergy in wt-p53 solid tumors.
Oncotarget 20110501
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A [3+2] dipolar cycloaddition route to 3-hydroxy-3-alkyl oxindoles: an approach to pyrrolidinoindoline alkaloids.
Organic letters 20110415
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Rhodium(II) acetate-catalyzed stereoselective synthesis, SAR and anti-HIV activity of novel oxindoles bearing cyclopropane ring.
European journal of medicinal chemistry 20110401
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Flexible strategy for syntheses of spirooxindoles using palladium-catalyzed carbosilylation and Sakurai-type cyclization.
Organic letters 20110401
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Chiral calcium VAPOL phosphate mediated asymmetric chlorination and Michael reactions of 3-substituted oxindoles.
Journal of the American Chemical Society 20110316
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Oxindole derivatives as inhibitors of TAK1 kinase.
Bioorganic & medicinal chemistry letters 20110315
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Catalytic thia-Sommelet-Hauser rearrangement: application to the synthesis of oxindoles.
Organic letters 20110304
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Molybdenum-catalyzed asymmetric allylic alkylation of 3-alkyloxindoles: reaction development and applications.
Chemistry (Weinheim an der Bergstrasse, Germany) 20110301
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Organocatalytic Michael-alkylation cascade: the enantioselective nitrocyclopropanation of oxindoles.
Chemistry (Weinheim an der Bergstrasse, Germany) 20110301
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Highly enantioselective catalytic benzoyloxylation of 3-aryloxindoles using chiral VAPOL calcium phosphate.
Angewandte Chemie (International ed. in English) 20110201
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Different biochemical correlates for different neuropsychiatric abnormalities in patients with cirrhosis.
Hepatology (Baltimore, Md.) 20110201
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Macrophyllionium and macrophyllines A and B, oxindole alkaloids from Uncaria macrophylla.
Journal of natural products 20110128
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Enantioselective Morita-Baylis-Hillman reaction of isatins with acrylates: facile creation of 3-hydroxy-2-oxindoles.
Organic letters 20110107
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Indole and 3-indolylacetonitrile inhibit spore maturation in Paenibacillus alvei.
BMC microbiology 20110101
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Synthesis and crystal structures of 5'-phenylspiro[indoline-3, 2'-pyrrolidin]-2-one derivatives.
Chemistry Central journal 20110101
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Neuroendocrine tumors of the gallbladder: a case report and review of the literature.
Journal of medical case reports 20110101
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Asymmetric conjugate addition of oxindoles to 2-chloroacrylonitrile: a highly effective organocatalytic strategy for simultaneous construction of 1,3-nonadjacent stereocenters leading to chiral pyrroloindolines.
Chemistry (Weinheim an der Bergstrasse, Germany) 20101227
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Indolyne experimental and computational studies: synthetic applications and origins of selectivities of nucleophilic additions.
Journal of the American Chemical Society 20101222
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Highly enantioselective organocatalytic α-amination reactions of aryl oxindoles: developing designer multifunctional alkaloid catalysts.
Organic letters 20101217
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Anticancer activity of the Uncaria tomentosa (Willd.) DC. preparations with different oxindole alkaloid composition.
Phytomedicine : international journal of phytotherapy and phytopharmacology 20101201
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A regio- and stereoselective 1,3-dipolar cycloaddition for the synthesis of novel spiro-pyrrolothiazolyloxindoles and their antitubercular evaluation.
European journal of medicinal chemistry 20101201
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Role of (68)Ga-DOTATOC PET/CT in the evaluation of primary pulmonary carcinoids.
The Korean journal of internal medicine 20101201
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A myosin V inhibitor based on privileged chemical scaffolds.
Angewandte Chemie (International ed. in English) 20101102
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Palladium-catalyzed carbo-heterofunctionalization of alkenes for the synthesis of oxindoles and spirooxindoles.
Organic letters 20101015
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Palladium-catalyzed tandem diperoxidation/C-H activation resulting in diperoxy-oxindole in air.
Organic letters 20101015
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Stereocontrolled creation of all-carbon quaternary stereocenters by organocatalytic conjugate addition of oxindoles to vinyl sulfone.
Angewandte Chemie (International ed. in English) 20101011
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Organocatalytic and electrophilic approach to oxindoles with C3-quaternary stereocenters.
Organic letters 20101001
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Copper-catalyzed asymmetric addition of arylboronates to isatins: a catalytic cycle involving alkoxocopper intermediates.
Chemical communications (Cambridge, England) 20100928
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The discovery of a series of N-substituted 3-(4-piperidinyl)-1,3-benzoxazolinones and oxindoles as highly brain penetrant, selective muscarinic M1 agonists.
Bioorganic & medicinal chemistry letters 20100915
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A facile method for the synthesis of oxindole based quaternary alpha-aminonitriles via the Strecker reaction.
Organic & biomolecular chemistry 20100907
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Melatonin metabolism in the central nervous system.
Current neuropharmacology 20100901
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Synthesis, electrochemical studies and anticancer activity of ferrocenyl oxindoles.
Dalton transactions (Cambridge, England : 2003) 20100821
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Branch-selective synthesis of oxindole and indene scaffolds: transition metal-controlled intramolecular aryl amidation leading to c3 reverse-prenylated oxindoles.
Organic letters 20100820
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First C-H activation route to oxindoles using copper catalysis.
Organic letters 20100806
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Highly enantioselective construction of spiro[4H-pyran-3,3'-oxindoles] through a domino Knoevenagel/Michael/cyclization sequence catalyzed by cupreine.
Organic letters 20100716
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Organocatalytic enantioselective hydroxymethylation of oxindoles with paraformaldehyde as C1 unit.
The Journal of organic chemistry 20100716
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Highly diastereo- and enantioselective Michael additions of 3-substituted oxindoles to maleimides catalyzed by chiral bifunctional thiourea-tertiary amine.
Organic letters 20100702
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Synthesis and structure-activity relationship of 6-arylureido-3-pyrrol-2-ylmethylideneindolin-2-one derivatives as potent receptor tyrosine kinase inhibitors.
Bioorganic & medicinal chemistry 20100701
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Organocatalytic Michael addition of unprotected 3-substituted oxindoles to nitroolefins.
Organic & biomolecular chemistry 20100628
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Highly enantioselective synthesis of 3-amino-2-oxindole derivatives: catalytic asymmetric alpha-amination of 3-substituted 2-oxindoles with a chiral scandium complex.
Chemistry (Weinheim an der Bergstrasse, Germany) 20100611
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Oxidative dearomatization in the synthesis of erythrina, oxindole and hexahydropyrrolo[2,3-b]indole skeletons.
Chemical communications (Cambridge, England) 20100607
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Peripheral and splanchnic indole and oxindole levels in cirrhotic patients: a study on the pathophysiology of hepatic encephalopathy.
The American journal of gastroenterology 20100601
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Synthesis of notoamide J: a potentially pivotal intermediate in the biosynthesis of several prenylated indole alkaloids.
The Journal of organic chemistry 20100507
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Six-component reactions for the stereoselective synthesis of 3-arylidene-2-oxindoles via sequential one-pot Ugi/Heck carbocyclization/Sonogashira/nucleophilic addition.
The Journal of organic chemistry 20100507
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Dimeric quinidine-catalyzed enantioselective aminooxygenation of oxindoles: an organocatalytic approach to 3-hydroxyoxindole derivatives.
Journal of the American Chemical Society 20100428
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An efficient stereoselective synthesis of 3-spirocyclopentene- and 3-spiropyrazole-2-oxindoles via 1,3-dipolar cycloaddition reaction.
Chemical communications (Cambridge, England) 20100428
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Oxindole synthesis by palladium-catalysed aromatic C-H alkenylation.
Chemical communications (Cambridge, England) 20100414
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1'-(2-Chloro-phen-yl)-5,6,5',6',7',7a'-hexa-hydro-1'H,1''H-dispiro-[imidazo[2,1-b][1,3]thia-zole-2,2'-pyrrolizine-3'(2'H),3''-indole]-2'',3(2H,3''H)-dione.
Acta crystallographica. Section E, Structure reports online 20100401
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Catalytic asymmetric synthesis of 3-(alpha-hydroxy-beta-carbonyl) oxindoles by a Sc(III)-catalyzed direct aldol-type reaction.
Chemistry (Weinheim an der Bergstrasse, Germany) 20100322
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Predictive comparative QSAR modelling of (phenylpiperazinyl-alkyl) oxindoles as selective 5-HT1A antagonists by stepwise regression, PCRA, FA-MLR and PLS techniques.
European journal of medicinal chemistry 20100301
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Organocatalytic tandem reaction to construct six-membered spirocyclic oxindoles with multiple chiral centres through a formal [2+2+2] annulation.
Chemistry (Weinheim an der Bergstrasse, Germany) 20100301
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Catalytic asymmetric synthesis of 3-aminooxindoles: enantiofacial selectivity switch in bimetallic vs monometallic Schiff base catalysis.
Journal of the American Chemical Society 20100203
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Catalytic double stereoinduction in asymmetric allylic alkylation of oxindoles.
Chemistry (Weinheim an der Bergstrasse, Germany) 20100104
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Catalytic asymmetric synthesis of substituted 3-hydroxy-2-oxindoles.
Angewandte Chemie (International ed. in English) 20100101
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Double-detargeted oncolytic adenovirus shows replication arrest in liver cells and retains neuroendocrine cell killing ability.
PloS one 20100101
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Covalent anchoring of chloroperoxidase and glucose oxidase on the mesoporous molecular sieve SBA-15.
International journal of molecular sciences 20100101
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Complete phenotypic recovery of an Alzheimer's disease model by a quinone-tryptophan hybrid aggregation inhibitor.
PloS one 20100101
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Enantioselective synthesis of substituted oxindoles and spirooxindoles with applications in drug discovery.
Current opinion in drug discovery & development 20100101
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(5''E)-1''-Benzyl-1'-methyl-5''-[4-(methyl-sulfan-yl)benzyl-idene]-4'-[4-(methyl-sulfan-yl)phen-yl]dispiro-[indoline-3,2'-pyrrolidine-3',3''-piperidine]-2,4''-dione dichloro-methane solvate.
Acta crystallographica. Section E, Structure reports online 20100101
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Rare tumors 20091228
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Expanding the scope of cinchona alkaloid-catalyzed enantioselective alpha-aminations of oxindoles: a versatile approach to optically active 3-amino-2-oxindole derivatives.
The Journal of organic chemistry 20091204
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Asymmetric construction of quaternary stereocenters by direct organocatalytic amination of 3-substituted oxindoles.
Chemical communications (Cambridge, England) 20091128
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Acta crystallographica. Section E, Structure reports online 20091101
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Functionalization and rearrangement of spirocyclohexadienyl oxindoles: experimental and theoretical investigations.
Chemistry (Weinheim an der Bergstrasse, Germany) 20091026
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Oxindole-Schiff base copper(II) complexes interactions with human serum albumin: spectroscopic, oxidative damage, and computational studies.
Journal of inorganic biochemistry 20091001
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Organocatalytic synthesis of spiro[pyrrolidin-3,3'-oxindoles] with high enantiopurity and structural diversity.
Journal of the American Chemical Society 20090930
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Selective synthesis of 3-aryl quinolin-2(1H)-ones and 3-(1-arylmethylene)oxindoles involving a 2-fold arene C-H activation process.
The Journal of organic chemistry 20090904
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Highly enantioselective and organocatalytic alpha-amination of 2-oxindoles.
Organic letters 20090903
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Midgut neuroendocrine tumours with liver metastases: results of the UKINETS study.
Endocrine-related cancer 20090901
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Acta crystallographica. Section E, Structure reports online 20090901
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Access to a welwitindolinone core using sequential cycloadditions.
Organic letters 20090820
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Efficient synthesis of 3,3-diheteroaromatic oxindole analogues and their in vitro evaluation for spermicidal potential.
Bioorganic & medicinal chemistry letters 20090815
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Aerobic oxidation of indolomorphinan without the 4,5-epoxy bridge and subsequent rearrangement of the oxidation product to spiroindolinonyl-C-normorphinan derivative.
Bioorganic & medicinal chemistry 20090815
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Stereoselective synthesis of spirocyclic oxindoles via Prins cyclizations.
Organic letters 20090806
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Stereocontrolled synthesis of spirooxindoles through Lewis acid-promoted [5 + 2]-annulation of chiral silyl alcohols.
Organic letters 20090806
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Antioxidant potential study of some synthesized N-heterocycles.
Bangladesh Medical Research Council bulletin 20090801
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Direct N-carbamoylation of 3-monosubstituted oxindoles with alkyl imidazole carboxylates.
The Journal of organic chemistry 20090717
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Organocatalytic asymmetric allylic alkylation of oxindoles with Morita-Baylis-Hillman carbonates.
Chemical communications (Cambridge, England) 20090714
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A homodinuclear Mn(III)2-Schiff base complex for catalytic asymmetric 1,4-additions of oxindoles to nitroalkenes.
Journal of the American Chemical Society 20090708
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Thiourea-catalyzed highly enantio- and diastereoselective additions of oxindoles to nitroolefins: application to the formal synthesis of (+)-physostigmine.
Journal of the American Chemical Society 20090701
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Soluble, semivolatile phenol and nitrogen compounds in milk-processing wastewaters.
Journal of dairy science 20090701
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Bioorganic & medicinal chemistry letters 20090615
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Oxindole synthesis by direct C-H, Ar-H coupling.
Chemical communications (Cambridge, England) 20090614
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Concise synthesis of the bicyclic scaffold of N-methylwelwitindolinone C isothiocyanate via an indolyne cyclization.
Organic letters 20090604
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Four tetracyclic oxindole alkaloids and a taberpsychine derivative from a Malayan Tabernaemontana.
Phytochemistry 20090601
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5-Hydroxytryptamine Receptor Subtypes and their Modulators with Therapeutic Potentials.
Journal of clinical medicine research 20090601
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Enantioselective synthesis of SM-130686 based on the development of asymmetric Cu(I)F catalysis to access 2-oxindoles containing a tetrasubstituted carbon.
Journal of the American Chemical Society 20090527
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Ruthenium-catalyzed alkylation of oxindole with alcohols.
The Journal of organic chemistry 20090515
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Ugi-post functionalization, from a single set of ugi-adducts to two distinct heterocycles by microwave-assisted palladium-catalyzed cyclizations: tuning the reaction pathways by ligand switch.
The Journal of organic chemistry 20090417
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The habenular nuclei: a conserved asymmetric relay station in the vertebrate brain.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090412
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Synthesis of oxindoles by tandem Heck-reduction-cyclization (HRC) from a single bifunctional, in situ generated Pd/C catalyst.
The Journal of organic chemistry 20090206
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(Z)-3-[(E)-3-Phenyl-allyl-idene]indolin-2-one.
Acta crystallographica. Section E, Structure reports online 20090201
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rac-(4R,17S,18R,26R)-Ethyl 4'-methoxy-carbonyl-5''-(4-methoxy-phen-yl)-1'-methyl-2,3''-dioxo-2'',3''-dihydro-indoline-3-spiro-2'-pyrrolidine-3'-spiro-2''-thia-zolo[3,2-a]pyrimidine-6''-carboxyl-ate.
Acta crystallographica. Section E, Structure reports online 20090201
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AcOLeDMAP and BnOLeDMAP: conformationally restricted nucleophilic catalysts for enantioselective rearrangement of indolyl acetates and carbonates.
Journal of the American Chemical Society 20090114
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The discovery of highly potent CGRP receptor antagonists.
Bioorganic & medicinal chemistry letters 20090101
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Oxindole synthesis by direct coupling of C(sp2)-H and C(sp3)-H centers.
Angewandte Chemie (International ed. in English) 20090101
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Targeting structural and stereochemical complexity by organocascade catalysis: construction of spirocyclic oxindoles having multiple stereocenters.
Angewandte Chemie (International ed. in English) 20090101
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Catalytic enantioselective stereoablative alkylation of 3-halooxindoles: facile access to oxindoles with C3 all-carbon quaternary stereocenters.
Angewandte Chemie (International ed. in English) 20090101
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A novel inhibitor of Chlamydophila pneumoniae protein kinase D (PknD) inhibits phosphorylation of CdsD and suppresses bacterial replication.
BMC microbiology 20090101
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Stereoselective synthesis of 3-alkylideneoxindoles by palladium-catalyzed cyclization reaction of 2-(alkynyl)aryl isocyanates with organoboron reagents.
Organic letters 20081106
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(13)C, (15)N CPMAS NMR and GIAO DFT calculations of stereoisomeric oxindole alkaloids from Cat's Claw (Uncaria tomentosa).
Solid state nuclear magnetic resonance 20081101
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Rearrangement of spirocyclic oxindoles with lithium amide bases.
Organic letters 20081016
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Diazonamide support studies: stereoselective formation of the C10 chiral center in both the CDEFG and AEFG fragments.
Organic letters 20080918
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Stereoselective oxidative rearrangement of 2-aryl tryptamine derivatives.
Organic letters 20080918
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Chiral N-heterocyclic carbene ligands for asymmetric catalytic oxindole synthesis.
Chemical communications (Cambridge, England) 20080914
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Intermolecular enolate heterocoupling: scope, mechanism, and application.
Journal of the American Chemical Society 20080827
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Organocatalytic stereoselective mannich reaction of 3-substituted oxindoles.
Organic letters 20080821
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Enantioselective synthesis of 3,3-disubstituted oxindoles through Pd-catalyzed cyanoamidation.
Organic letters 20080807
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Orthogonal Pd- and Cu-based catalyst systems for C- and N-arylation of oxindoles.
Journal of the American Chemical Society 20080723
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Palladium-catalyzed C-H functionalization of N-arylpropiolamides with aryliodonium salts: selective synthesis of 3-(1-arylmethylene)oxindoles.
The Journal of organic chemistry 20080718
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Facile and general synthesis of quaternary 3-aminooxindoles.
Organic letters 20080703
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Synthesis of (2-oxoindolin-3-ylidene)methyl acetates involving a C-H functionalization process.
Organic letters 20080501
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Palladium-catalyzed alpha-arylation of oxindoles.
Organic letters 20080403
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Design, synthesis, and SAR of new pyrrole-oxindole progesterone receptor modulators leading to 5-(7-fluoro-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile (WAY-255348).
Journal of medicinal chemistry 20080327
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Double-strand DNA cleavage induced by oxindole-Schiff base copper(II) complexes with potential antitumor activity.
Journal of inorganic biochemistry 20080101
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Biotransformation of indole derivatives by mycelial cultures.
Zeitschrift fur Naturforschung. C, Journal of biosciences 20080101
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Palladium-catalyzed tandem Heck reaction/C-H functionalization--preparation of spiro-indane-oxindoles.
Angewandte Chemie (International ed. in English) 20080101
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Design and synthesis of novel oxindoles as potential non-nucleosidic reverse transcriptase inhibitors against HIV.
Nucleic acids symposium series (2004) 20080101
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Mo-catalyzed regio-, diastereo-, and enantioselective allylic alkylation of 3-aryloxindoles.
Journal of the American Chemical Society 20071128
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Potent oxindole based human beta3 adrenergic receptor agonists.
Bioorganic & medicinal chemistry letters 20071115
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Enantioselective construction of spirocyclic oxindolic cyclopentanes by palladium-catalyzed trimethylenemethane-[3+2]-cycloaddition.
Journal of the American Chemical Society 20071017
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Synthesis of novel functionalized 3-spiropyrrolizidine and 3-spiropyrrolidine oxindoles from Baylis-Hillman adducts of isatin and heteroaldehydes with azomethine ylides via [3+2]-cycloaddition.
Organic letters 20071011
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[Association between the TPH2 gene and suicidal behavior].
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20071001
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The oxindole/imidazole derivative C16 reduces in vivo brain PKR activation.
FEBS letters 20070918
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Straightforward stereoselective synthesis of spiro-epoxyoxindoles.
Organic letters 20070426
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Antiproliferative effects of mitraphylline, a pentacyclic oxindole alkaloid of Uncaria tomentosa on human glioma and neuroblastoma cell lines.
Phytomedicine : international journal of phytotherapy and phytopharmacology 20070401
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Polyhydroxylated indolines and oxindoles from C-glycosides via sequential Henry reaction, Michael addition, and reductive amination/amidation.
The Journal of organic chemistry 20070330
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Isatinones A and B, new antifungal oxindole alkaloids from Isatis costata.
Molecules (Basel, Switzerland) 20070206
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Structure-activity relationship study of oxindole-based inhibitors of cyclin-dependent kinases based on least-squares support vector machines.
Analytica chimica acta 20070109
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Simple and one-pot protocol for synthesis of indene-spiro-oxindoles involving tandem Prins and Friedel-Crafts reactions.
Organic letters 20070104
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3D-QSAR CoMFA study on oxindole derivatives as cyclin dependent kinase 1 (CDK1) and cyclin dependent kinase 2 (CDK2) inhibitors.
Medicinal chemistry (Shariqah (United Arab Emirates)) 20070101
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A traceless approach for the solid-phase parallel synthesis of trisubstituted oxindoles.
Journal of combinatorial chemistry 20070101
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Cinchona-alkaloid-catalyzed enantioselective direct aldol-type reaction of oxindoles with ethyl trifluoropyruvate.
Angewandte Chemie (International ed. in English) 20070101
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Endogenous oxidized indoles share inhibitory potency against [3H]isatin binding in rat brain.
Journal of neural transmission. Supplementum 20070101
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Lewis acid-catalyzed enantioselective hydroxylation reactions of oxindoles and beta-keto esters using DBFOX ligand.
Journal of the American Chemical Society 20061227
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Enantioselective arylation of 2-methylacetoacetates catalyzed by CuI/trans-4-hydroxy-L-proline at low reaction temperatures.
Journal of the American Chemical Society 20061220
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Efficient asymmetric synthesis of novel gastrin receptor antagonist AG-041R via highly stereoselective alkylation of oxindole enolates.
The Journal of organic chemistry 20061027
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An efficient synthesis of a spirocyclic oxindole analogue.
Molecules (Basel, Switzerland) 20060914
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Solid phase approaches to N-heterocycles using a sulfur linker cleaved by SmI2.
The Journal of organic chemistry 20060818
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Discovery and SAR of oxindole-pyridine-based protein kinase B/Akt inhibitors for treating cancers.
Bioorganic & medicinal chemistry letters 20060701
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Inhibition of amyloid fibril formation and cytotoxicity by hydroxyindole derivatives.
Biochemistry 20060418
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Selective kinase inhibition by exploiting differential pathway sensitivity.
Chemistry & biology 20060401
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Diastereoselection in the formation of spirocyclic oxindoles by the intramolecular Heck reaction.
The Journal of organic chemistry 20060331
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Highly diastereoselective one-pot synthesis of spirocyclic oxindoles through intramolecular Ullmann coupling and Claisen rearrangement.
Angewandte Chemie (International ed. in English) 20060327
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Synthesis of the putative structure of fistulosin using the ruthenium-catalyzed cycloisomerization of diene.
The Journal of organic chemistry 20060203
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Synthesis and biological evaluation of novel phenylcarbazoles as potential anticancer agents.
Journal of medicinal chemistry 20060126
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A new chemical tool for exploring the physiological function of the PDE2 isozyme.
Bioorganic & medicinal chemistry letters 20060115
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Liver metastases of neuroendocrine tumours; early reduction of tumour load to improve life expectancy.
World journal of surgical oncology 20060101
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Binding of an oxindole alkaloid from Uncaria tomentosa to amyloid protein (Abeta1-40).
Zeitschrift fur Naturforschung. C, Journal of biosciences 20060101
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A novel method for observing proteins in vivo using a small fluorescent label and multiphoton imaging.
The Biochemical journal 20050915
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Stereoselective synthesis of 3-alkylideneoxindoles via palladium-catalyzed domino reactions.
The Journal of organic chemistry 20050819
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Antiangiogenic drugs synergize with a membrane macrophage colony-stimulating factor-based tumor vaccine to therapeutically treat rats with an established malignant intracranial glioma.
Journal of immunology (Baltimore, Md. : 1950) 20050301
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Recent developments on KCNQ potassium channel openers.
Current medicinal chemistry 20050101
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Palladium-catalyzed asymmetric allylation of prochiral nucleophiles: synthesis of 3-allyl-3-aryl oxindoles.
Angewandte Chemie (International ed. in English) 20041227
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Involvement of photooxidation of melanogenic precursors in prolonged pigmentation induced by ultraviolet A.
The Journal of investigative dermatology 20040201
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[Effects of 3-substituted aryl oxindole(PH II-7) on cell cycle of tumor cells].
Yao xue xue bao = Acta pharmaceutica Sinica 20031101
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Prooxidant activity of free radicals derived from phenol-containing neurotransmitters.
Toxicology 20020801
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Efficient formal total synthesis of physostigmine and physovenine: conformational analysis of key intermediates.
Journal of natural products 20020201
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[Effect of oxidized indoles on monoamine oxidase activity in the rat brain mitochondria].
Voprosy meditsinskoi khimii 20020101
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Expression of the Caldariomyces fumago chloroperoxidase in Aspergillus niger and characterization of the recombinant enzyme.
The Journal of biological chemistry 20010525
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Chloroperoxidase-catalyzed enantioselective oxidations in hydrophobic organic media.
Biotechnology and bioengineering 20010305
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Crystal structure of a conformation-selective casein kinase-1 inhibitor.
The Journal of biological chemistry 20000630
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Characterization of novel inhibitors of cyclin-dependent kinases.
Biochemical and biophysical research communications 19990714