1701-70-8 | 1-(Pyridin-3-yl)butan-1-one

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$66.00	$47.00
1g	95%	in stock	$155.00	$108.00
5g	95%	in stock	$473.00	$331.00
10g	95%	in stock	$783.00	$548.00
25g	95%	in stock	$1,536.00	$1,075.00

Description

• Catalog Number: AF01499
• Chemical Name: 1-(Pyridin-3-yl)butan-1-one
• CAS Number: 1701-70-8
• Molecular Formula: C9H11NO
• Molecular Weight: 149.1897
• MDL Number: MFCD12153276
• SMILES: CCCC(=O)c1cccnc1

Computed Properties

• Complexity: 134
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• XLogP3: 1.3

Literature

• Low fidelity bypass of O(2)-(3-pyridyl)-4-oxobutylthymine, the most persistent bulky adduct produced by the tobacco specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by model DNA polymerases.

  Chemical research in toxicology 20120618

• Tobacco-specific nitrosamine-derived O2-alkylthymidines are potent mutagenic lesions in SOS-induced Escherichia coli.

  Chemical research in toxicology 20111121

• Kinetic analysis of translesion synthesis opposite bulky N2- and O6-alkylguanine DNA adducts by human DNA polymerase REV1.

  The Journal of biological chemistry 20080829

• Differences in the rate of repair of O6-alkylguanines in different sequence contexts by O6-alkylguanine-DNA alkyltransferase.

  Chemical research in toxicology 20071201