17176-77-1 | Dibenzyl phosphite

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$16.00	$11.00
5g	95%	in stock	$34.00	$24.00
10g	95%	in stock	$50.00	$35.00
25g	95%	in stock	$66.00	$47.00
100g	95%	in stock	$235.00	$165.00
500g	95%	in stock	$694.00	$486.00

Description

• Catalog Number: AB45864
• Chemical Name: Dibenzyl phosphite
• CAS Number: 17176-77-1
• Molecular Formula: C14H15O3P
• Molecular Weight: 262.2409
• MDL Number: MFCD00004774
• SMILES: O=P(OCc1ccccc1)OCc1ccccc1

Computed Properties

• Complexity: 221
• Covalently-Bonded Unit Count: 1
• Formal Charge: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• XLogP3: 3

Upstream Synthesis Route

Dibenzyl phosphonate is a versatile compound commonly employed in chemical synthesis as a crucial building block. Its unique chemical properties make it a valuable tool for organic chemists in various synthetic processes. One primary application of dibenzyl phosphonate is its role as a phosphonate protecting group. By utilizing dibenzyl phosphonate as a protective reagent, chemists can selectively shield specific functional groups in complex molecules during synthetic reactions. This enables precise control over the reaction outcomes and facilitates the synthesis of intricate organic compounds. Furthermore, dibenzyl phosphonate can participate in various transformations to introduce phosphonate groups into target molecules, serving as a key intermediate in the synthesis of phosphonate derivatives with diverse applications in medicinal chemistry, materials science, and other fields. Its compatibility with a wide range of synthetic methodologies highlights its significance as a valuable tool for chemists seeking to construct complex molecules with precision and efficiency.

Literature

• Total synthesis of chiricanine A, arahypin-1, trans-arachidin-2, trans-arachidin-3, and arahypin-5 from peanut seeds.

  Journal of natural products 20110425

• Antiviral activity and mechanism of action of novel thiourea containing chiral phosphonate on tobacco mosaic virus.

  International journal of molecular sciences 20110101

• Unexpected relative aqueous solubilities of a phosphotyrosine analogue and two phosphonate derivatives.

  Journal of the American Chemical Society 20050406

• The obligatory action of protein tyrosine phosphatases in ACTH-stimulated steroidogenesis is exerted at the level of StAR protein.

  Endocrine research 20021101