17440-83-4 | 2-Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, hydrochloride, hydrate (1:1:2)

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$18.00	$12.00
1g	95%	in stock	$34.00	$24.00
5g	95%	in stock	$114.00	$80.00
25g	95%	in stock	$372.00	$260.00
100g	95%	in stock	$1,024.00	$717.00

Description

• Catalog Number: AA92663
• Chemical Name: 2-Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, hydrochloride, hydrate (1:1:2)
• CAS Number: 17440-83-4
• Molecular Formula: C6H13Cl2N7O3
• Molecular Weight: 302.1185
• MDL Number: MFCD00077316
• SMILES: NN=CNC(=O)c1nc(Cl)c(nc1N)N.Cl.O.O

Computed Properties

• Complexity: 279
• Covalently-Bonded Unit Count: 4
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 7
• Rotatable Bond Count: 1

Literature

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  European journal of oral sciences 20131201

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  The Analyst 20121121

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  American journal of physiology. Cell physiology 20121101

• Modulation of vH+-ATPase is part of the functional adaptation of sheep rumen epithelium to high-energy diet.

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• Molecular expression and functional activity of sodium dependent multivitamin transporter in human prostate cancer cells.

  International journal of pharmaceutics 20121015

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  Acta physiologica (Oxford, England) 20121001

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  Cell biology and toxicology 20121001

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• Sequential nephron blockade versus sequential renin-angiotensin system blockade in resistant hypertension: a prospective, randomized, open blinded endpoint study.

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  Journal of cellular and molecular medicine 20120501

• Amiloride off-target effect inhibits podocyte urokinase receptor expression and reduces proteinuria.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120501

• Performance of cell-penetrating peptide-linked polymers physically mixed with poorly membrane-permeable molecules on cell membranes.

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• Effects of potassium-sparing versus thiazide diuretics on glucose tolerance: new data on an old topic.

  Hypertension (Dallas, Tex. : 1979) 20120501

• The Na+/H+ exchanger NHE1, but not the Na+, HCO3(-) cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2.

  Cancer letters 20120428

• Intracellular pH regulation in unstimulated Calliphora salivary glands is Na+ dependent and requires V-ATPase activity.

  The Journal of experimental biology 20120415

• Contribution of residues in second transmembrane domain of ASIC1a protein to ion selectivity.

  The Journal of biological chemistry 20120413

• DNA conjugated SWCNTs enter endothelial cells via Rac1 mediated macropinocytosis.

  Nano letters 20120411

• Expression of acid-sensing ion channels of gastric mucosa from patients with Henoch-Schönlein purpura.

  Journal of pediatric gastroenterology and nutrition 20120401

• Blockade of acid-sensing ion channels protects articular chondrocytes from acid-induced apoptotic injury.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20120401

• Permeability of the arachnoid and pia mater. The role of ion channels in the leptomeningeal physiology.

  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20120401

• Combination of amlodipine plus angiotensin receptor blocker or diuretics in high-risk hypertensive patients: a 96-week efficacy and safety study.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20120401

• 2-Amidino analogs of glycine-amiloride conjugates: inhibitors of urokinase-type plasminogen activator.

  Bioorganic & medicinal chemistry letters 20120401

• Comparative characterization of Na+ transport in Cyprinodon variegatus variegatus and Cyprinodon variegatus hubbsi: a model species complex for studying teleost invasion of freshwater.

  The Journal of experimental biology 20120401

• CFTR is restricted to a small population of high expresser cells that provide a forskolin-sensitive transepithelial Cl- conductance in the proximal colon of the possum, Trichosurus vulpecula.

  The Journal of experimental biology 20120401

• pH-sensitive capsules as intracellular optical reporters for monitoring lysosomal pH changes upon stimulation.

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  American journal of physiology. Renal physiology 20120315

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  The Cochrane database of systematic reviews 20120314

• Allergic sensitization enhances anion current responsiveness of murine trachea to PAR-2 activation.

  Pflugers Archiv : European journal of physiology 20120301

• Effects of rhinovirus infection on the expression and function of cystic fibrosis transmembrane conductance regulator and epithelial sodium channel in human nasal mucosa.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20120301

• Pharmacological characterization of the diuretic effect of Hibiscus sabdariffa Linn (Malvaceae) extract.

  Journal of ethnopharmacology 20120215

• Glioma-specific cation conductance regulates migration and cell cycle progression.

  The Journal of biological chemistry 20120203

• Molecular and functional characterization of the human platelet Na(+) /Ca(2+) exchangers.

  British journal of pharmacology 20120201

• Induction of angiopoietin-2 after spinal cord injury.

  Neuroscience 20120127

• Fluorescence properties of the Na⁺/H⁺exchanger inhibitor HMA (5-(N,N-hexamethylene)amiloride) are modulated by intracellular pH.

  European journal of histochemistry : EJH 20120120

• Functional role of NHE4 as a pH regulator in rat and human colonic crypts.

  American journal of physiology. Cell physiology 20120115

• Discovery of a novel chemotype of potent human ENaC blockers using a bioisostere approach. Part 1: quaternary amines.

  Bioorganic & medicinal chemistry letters 20120115

• Flow cytometry analysis reveals a decrease in intracellular sodium during sperm capacitation.

  Journal of cell science 20120115

• A single, selective and simple validated method for simultaneous estimation of amiloride and hydrochlorothiazide in human plasma by liquid chromatography-tandem mass spectrometry.

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  American journal of physiology. Cell physiology 20120101

• Endogenous surface expression of ΔF508-CFTR mediates cAMP-stimulated Cl(-) current in CFTR(ΔF508/ΔF508) pig thyroid epithelial cells.

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• The antinociceptive activity of intrathecally administered amiloride and its interactions with morphine and clonidine in rats.

  The journal of pain : official journal of the American Pain Society 20120101

• Amiloride enhances antigen specific CTL by faciliting HBV DNA vaccine entry into cells.

  PloS one 20120101

• Nonsteroidal anti-inflammatory drugs alter the human mesothelial pleural permeability via ion cellular transportation by inhibiting prostaglandin synthesis.

  Respiration; international review of thoracic diseases 20120101

• Primary aldosteronism in pregnancy.

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  Tsitologiia 20120101

• Potential role of sodium-proton exchangers in the low concentration arsenic trioxide-increased intracellular pH and cell proliferation.

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• Blockade of acid sensing ion channels attenuates the augmented exercise pressor reflex in rats with chronic femoral artery occlusion.

  The Journal of physiology 20111215

• Nonproton ligand sensing domain is required for paradoxical stimulation of acid-sensing ion channel 3 (ASIC3) channels by amiloride.

  The Journal of biological chemistry 20111209

• FXYD5 (dysadherin) regulates the paracellular permeability in cultured kidney collecting duct cells.

  American journal of physiology. Renal physiology 20111201

• Integument structure and function in juvenile Xenopus laevis with disrupted thyroid balance.

  General and comparative endocrinology 20111201

• Pharmacological characterisation of apical Na+ and Cl- transport mechanisms of the anal papillae in the larval mosquito Aedes aegypti.

  The Journal of experimental biology 20111201

• Human keratinocytes express AIM2 and respond to dsDNA with IL-1β secretion.

  Experimental dermatology 20111201

• Requirement of potassium for the action of anti-diuretic hormone (ADH) on frog skin.

  Zoological science 20111201

• Lysophosphatidic acid is a modulator of cyst growth in autosomal dominant polycystic kidney disease.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20111201

• Synthesis and preliminary evaluation of amiloride analogs as inhibitors of the urokinase-type plasminogen activator (uPA).

  Bioorganic & medicinal chemistry letters 20111115

• Anti-tumour/metastasis effects of the potassium-sparing diuretic amiloride: an orally active anti-cancer drug waiting for its call-of-duty?

  International journal of cancer 20111101

• β2-Adrenergics in hypoxia desensitize receptors but blunt inhibition of reabsorption in rat lungs.

  American journal of respiratory cell and molecular biology 20111101

• Tolvaptan inhibits ERK-dependent cell proliferation, Cl⁻ secretion, and in vitro cyst growth of human ADPKD cells stimulated by vasopressin.

  American journal of physiology. Renal physiology 20111101

• The pharmacological profile of brain liver intestine Na+ channel: inhibition by diarylamidines and activation by fenamates.

  Molecular pharmacology 20111101

• Ammonia excretion via Rhcg1 facilitates Na⁺ uptake in larval zebrafish, Danio rerio, in acidic water.

  American journal of physiology. Regulatory, integrative and comparative physiology 20111101

• The role of rectal chloride secretion in childhood constipation.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20111101

• Strain differences in the neural, behavioral, and molecular correlates of sweet and salty taste in naive, ethanol- and sucrose-exposed P and NP rats.

  Journal of neurophysiology 20111101

• Phosphatidylinositol 4,5-bisphosphate stimulates alveolar epithelial fluid clearance in male and female adult rats.

  American journal of physiology. Lung cellular and molecular physiology 20111101

• Cross-reactivity of acid-sensing ion channel and Na⁺-H⁺ exchanger antagonists with nicotinic acetylcholine receptors.

  The Journal of physiology 20111101

• Ebola virus enters host cells by macropinocytosis and clathrin-mediated endocytosis.

  The Journal of infectious diseases 20111101

• The Ebola virus glycoprotein mediates entry via a non-classical dynamin-dependent macropinocytic pathway.

  Virology 20111025

• Mechanism of ribonuclease A endocytosis: analogies to cell-penetrating peptides.

  Biochemistry 20111004

• The influence of benzamil hydrochloride on the evolution of hyponatremic brain edema as assessed by in vivo MRI study in rats.

  Acta neurochirurgica 20111001

• Enhancement of alveolar epithelial sodium channel activity with decreased cystic fibrosis transmembrane conductance regulator expression in mouse lung.

  American journal of physiology. Lung cellular and molecular physiology 20111001

• ENaC structure and function in the wake of a resolved structure of a family member.

  American journal of physiology. Renal physiology 20111001

• Regulation of hypothalamic renin-angiotensin system and oxidative stress by aldosterone.

  Experimental physiology 20111001

• Acid-sensing channels in human bladder: expression, function and alterations during bladder pain syndrome.

  The Journal of urology 20111001

• Presynaptic regulation of quantal size: K+/H+ exchange stimulates vesicular glutamate transport.

  Nature neuroscience 20111001

• Bicarbonate, NBCe1, NHE, and carbonic anhydrase activity enhance lactate-H+ transport in bovine corneal endothelium.

  Investigative ophthalmology & visual science 20111001

• DEG/ENaC but not TRP channels are the major mechanoelectrical transduction channels in a C. elegans nociceptor.

  Neuron 20110908

• Hypericum perforatum differentially affects corticosteroid receptor-mRNA expression in human monocytic U-937 cells.

  Journal of psychiatric research 20110901

• Cleavage of endogenous γENaC and elevated abundance of αENaC are associated with increased Na⁺ transport in response to apical fluid volume expansion in human H441 airway epithelial cells.

  Pflugers Archiv : European journal of physiology 20110901

• Quality of life in patients with bilateral primary aldosteronism before and during treatment with spironolactone and/or amiloride, including a comparison with our previously published results in those with unilateral disease treated surgically.

  The Journal of clinical endocrinology and metabolism 20110901

• Stimulation of erythrocyte phospholipid scrambling by enniatin A.

  Molecular nutrition & food research 20110901

• Cellular localization of NKCC2 and its possible role in the Cl- absorption in the rat and human distal colonic epithelia.

  Translational research : the journal of laboratory and clinical medicine 20110901

• Effect of aldosterone on the amplification of oncolytic vaccinia virus in human cancer lines.

  The Korean journal of hepatology 20110901

• Role of the spinal Na+/H+ exchanger in formalin-induced nociception.

  Neuroscience letters 20110821

• A clinical phenotype mimicking essential hypertension in a newly discovered family with Liddle's syndrome.

  American journal of hypertension 20110801

• Gut sensing of dietary K⁺ intake increases renal K⁺excretion.

  American journal of physiology. Regulatory, integrative and comparative physiology 20110801

• Alveolar epithelial CNGA1 channels mediate cGMP-stimulated, amiloride-insensitive, lung liquid absorption.

  Pflugers Archiv : European journal of physiology 20110801

• High sodium intake increases HCO(3)- absorption in medullary thick ascending limb through adaptations in basolateral and apical Na+/H+ exchangers.

  American journal of physiology. Renal physiology 20110801

• Evidence for NHE3-mediated Na transport in sheep and bovine forestomach.

  American journal of physiology. Regulatory, integrative and comparative physiology 20110801

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  Deutsche medizinische Wochenschrift (1946) 20110801

• Net sodium fluxes change significantly at anatomically distinct root zones of rice (Oryza sativa L.) seedlings.

  Journal of plant physiology 20110715

• Identification of non-amidine inhibitors of acid-sensing ion channel-3 (ASIC3).

  Bioorganic & medicinal chemistry letters 20110715

• Plasma-accessible carbonic anhydrase at the tissue of a teleost fish may greatly enhance oxygen delivery: in vitro evidence in rainbow trout, Oncorhynchus mykiss.

  The Journal of experimental biology 20110715

• Hyperviscous airway periciliary and mucous liquid layers in cystic fibrosis measured by confocal fluorescence photobleaching.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110701

• Methods for stable recording of short-circuit current in a Na+-transporting epithelium.

  American journal of physiology. Cell physiology 20110701

• Conservation of Na+ vs. K+ by the rat cortical collecting duct.

  American journal of physiology. Renal physiology 20110701

• Sepsis impairs alveolar epithelial function by downregulating Na-K-ATPase pump.

  American journal of physiology. Lung cellular and molecular physiology 20110701

• Body fluid expansion in acromegaly is related to enhanced epithelial sodium channel (ENaC) activity.

  The Journal of clinical endocrinology and metabolism 20110701

• Amiloride improves locomotor recovery after spinal cord injury.

  Journal of neurotrauma 20110701

• High capacity Na+/H+ exchange activity in mineralizing osteoblasts.

  Journal of cellular physiology 20110601

• Decoupling of the catalytic and transport activities of complex I from Rhodothermus marinus by sodium/proton antiporter inhibitor.

  ACS chemical biology 20110520

• Further antinociceptive effects of myricitrin in chemical models of overt nociception in mice.

  Neuroscience letters 20110520

• The combination of amlodipine and angiotensin receptor blocker or diuretics in high-risk hypertensive patients: rationale, design and baseline characteristics.

  Journal of human hypertension 20110401

• Insulin activates epithelial sodium channel (ENaC) via phosphoinositide 3-kinase in mammalian taste receptor cells.

  American journal of physiology. Cell physiology 20110401

• Antinatriuretic effect of vasopressin in humans is amiloride sensitive, thus ENaC dependent.

  Clinical journal of the American Society of Nephrology : CJASN 20110401

• Preserved response to diuretics in rosiglitazone-treated subjects with insulin resistance: a randomized double-blind placebo-controlled crossover study.

  Clinical pharmacology and therapeutics 20110401

• The dilated TRPA1 channel pore state is blocked by amiloride and analogues.

  Brain research 20110324

• Suppression of Na+/H + exchanger 1 by RNA interference or amiloride inhibits human hepatoma cell line SMMC-7721 cell invasion.

  Medical oncology (Northwood, London, England) 20110301

• Amiloride reduces sodium transport and accumulation in the succulent xerophyte Zygophyllum xanthoxylum under salt conditions.

  Biological trace element research 20110301

• Increased renal ENaC subunits and sodium retention in rats with chronic heart failure.

  American journal of physiology. Renal physiology 20110301

• Characterization of butyrate uptake by nontransformed intestinal epithelial cell lines.

  The Journal of membrane biology 20110301

• Evaluation of the secretory response to endogenous and exogenous prostaglandins in mucosa from the proximal and distal portions of the colon of dogs.

  American journal of veterinary research 20110301

• Dissection of the influenza A virus endocytic routes reveals macropinocytosis as an alternative entry pathway.

  PLoS pathogens 20110301

• Exercise reduces airway sodium ion reabsorption in cystic fibrosis but not in exercise asthma.

  The European respiratory journal 20110201

• Effects of sodium selenite and amiloride on calvarial calcification in closing small cranial defects.

  Journal of neurosurgery 20110201

• Nasal potential measurements on the nasal floor and under the inferior turbinate: does it matter?

  Pediatric pulmonology 20110201

• Stiff endothelial cell syndrome in vascular inflammation and mineralocorticoid excess.

  Hypertension (Dallas, Tex. : 1979) 20110201

• C-reactive protein makes human endothelium stiff and tight.

  Hypertension (Dallas, Tex. : 1979) 20110201

• Acid-sensing ion channel 1 is involved in both axonal injury and demyelination in multiple sclerosis and its animal model.

  Brain : a journal of neurology 20110201

• Pregnancy in inherited hypokalemic salt-losing renal tubular disorder.

  Obstetrics and gynecology 20110201

• Expression and modulation of Na(+) /H(+) exchanger 1 gene in hepatocellular carcinoma: A potential therapeutic target.

  Journal of gastroenterology and hepatology 20110201

• Antiepileptic intranasal Amiloride loaded mucoadhesive nanoemulsion: development and safety assessment.

  Journal of biomedical nanotechnology 20110201

• Effect of histamine on the electrophysiology of the human parietal pleura.

  Molecular and cellular endocrinology 20110130

• Amiloride modulates alternative splicing in leukemic cells and resensitizes Bcr-AblT315I mutant cells to imatinib.

  Cancer research 20110115

• Na(+)-H(+) exchange blockade, using amiloride, decreases the inflammatory response following hemorrhagic shock and resuscitation in rats.

  European journal of pharmacology 20110110

• Nitric oxide inhibits highly selective sodium channels and the Na+/K+-ATPase in H441 cells.

  American journal of respiratory cell and molecular biology 20110101

• Sodium hydrogen exchanger as a mediator of hydrostatic edema-induced intestinal contractile dysfunction.

  Surgery 20110101

• Sodium dependence of lysophosphatidylcholine-induced caspase-1 activity and reactive oxygen species generation.

  Immunobiology 20110101

• Regulation of endogenous ENaC functional expression by CFTR and ΔF508-CFTR in airway epithelial cells.

  American journal of physiology. Lung cellular and molecular physiology 20110101

• Expression of acid-sensing ion channels in intestinal epithelial cells and their role in the regulation of duodenal mucosal bicarbonate secretion.

  Acta physiologica (Oxford, England) 20110101

• Impaired aldosterone responsiveness in corticosteroid binding globulin deficient mice.

  Acta physiologica (Oxford, England) 20110101

• Dural afferents express acid-sensing ion channels: a role for decreased meningeal pH in migraine headache.

  Pain 20110101

• 11β-hydroxysteroid dehydrogenase type 2 deficiency accelerates atherogenesis and causes proinflammatory changes in the endothelium in apoe-/- mice.

  Endocrinology 20110101

• Antinociception produced by Thalassia testudinum extract BM-21 is mediated by the inhibition of acid sensing ionic channels by the phenolic compound thalassiolin B.

  Molecular pain 20110101

• A comparison between diuretics and angiotensin-receptor blocker agents in patients with stage I hypertension (PREVER-treatment trial): study protocol for a randomized double-blind controlled trial.

  Trials 20110101

• Prevention of hypertension in patients with pre-hypertension: protocol for the PREVER-prevention trial.

  Trials 20110101

• [New insights into the pathophysiology of oedema in nephrotic syndrome].

  Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20110101

• Na+/Ca2+ exchanger inhibitors inhibit neurite outgrowth in PC12 cells.

  Journal of pharmacological sciences 20110101

• Small molecule amiloride modulates oncogenic RNA alternative splicing to devitalize human cancer cells.

  PloS one 20110101

• Defective CFTR expression and function are detectable in blood monocytes: development of a new blood test for cystic fibrosis.

  PloS one 20110101

• Stimulation of suicidal erythrocyte death by benzethonium.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101

• The cardioprotective effect of brief acidic reperfusion after ischemia in perfused rat hearts is not mimicked by inhibition of the Na(+)/H(+) exchanger NHE1.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101

• Contribution of the amiloride-sensitive component and the Na+/H+ exchanger to renal responsiveness to vasoconstrictors.

  Pharmacology 20110101

• Ketamine inhibits lung fluid clearance through reducing alveolar sodium transport.

  Journal of biomedicine & biotechnology 20110101

• Acid-sensing ion channel 1a is involved in retinal ganglion cell death induced by hypoxia.

  Molecular vision 20110101

• Duffy antigen receptor for chemokines mediates chemokine endocytosis through a macropinocytosis-like process in endothelial cells.

  PloS one 20110101

• [Mechanism of epithelial sodium channel (ENaC) regulation by cortactin: involvement of dynamin].

  Tsitologiia 20110101

• Dual inhibition of sodium-mediated proton and calcium efflux triggers non-apoptotic cell death in malignant gliomas.

  Brain research 20101202

• Allergic airway inflammation induces a pro-secretory epithelial ion transport phenotype in mice.

  The European respiratory journal 20101201

• Ammonia uptake in Manduca sexta midgut is mediated by an amiloride sensitive cation/proton exchanger: Transport studies and mRNA expression analysis of NHE7, 9, NHE8, and V-ATPase (subunit D).

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20101201

• Altered ion transport by thyroid epithelia from CFTR(-/-) pigs suggests mechanisms for hypothyroidism in cystic fibrosis.

  Experimental physiology 20101201

• Mechanism of hCG-induced spermiation in the toad Rhinella arenarum (Amphibia, Anura).

  General and comparative endocrinology 20101201

• Connecting tubule glomerular feedback antagonizes tubuloglomerular feedback in vivo.

  American journal of physiology. Renal physiology 20101201

• A predictive ligand-based Bayesian model for human drug-induced liver injury.

  Drug metabolism and disposition: the biological fate of chemicals 20101201

• Effect of intracerebroventricular benzamil on cardiovascular and central autonomic responses to DOCA-salt treatment.

  American journal of physiology. Regulatory, integrative and comparative physiology 20101201

• A real-time screening assay for GIRK1/4 channel blockers.

  Journal of biomolecular screening 20101201

• Essential structural features of TNF-α lectin-like domain derived peptides for activation of amiloride-sensitive sodium current in A549 cells.

  Journal of medicinal chemistry 20101125

• TAT fusion protein transduction into isolated mitochondria is accelerated by sodium channel inhibitors.

  Biochemistry 20101109

• Inhibition of acid-sensing ion channels in articular chondrocytes by amiloride attenuates articular cartilage destruction in rats with adjuvant arthritis.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20101101

• Amiloride lowers arterial pressure in cyp1a1ren-2 transgenic rats without affecting renal vascular function.

  Journal of hypertension 20101101

• Increased renal alpha-epithelial sodium channel (ENAC) protein and increased ENAC activity in normal pregnancy.

  American journal of physiology. Regulatory, integrative and comparative physiology 20101101

• Effect of metabolic acidosis on neonatal proximal tubule acidification.

  American journal of physiology. Regulatory, integrative and comparative physiology 20101101

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Na(+)- and H(+)-dependent motility in the coral pathogen Vibrio shilonii.

  FEMS microbiology letters 20101101

• NMR structure and ion channel activity of the p7 protein from hepatitis C virus.

  The Journal of biological chemistry 20101008

• A nonproton ligand sensor in the acid-sensing ion channel.

  Neuron 20101006

• Amiloride derivatives modulate PS externalization in neutrophil-like PLB-985 cells.

  Biochemical pharmacology 20101001

• Lipopolysaccharide hyperpolarizes guinea pig airway epithelium by increasing the activities of the epithelial Na(+) channel and the Na(+)-K(+) pump.

  American journal of physiology. Lung cellular and molecular physiology 20101001

• A single amino acid tunes Ca2+ inhibition of brain liver intestine Na+ channel (BLINaC).

  The Journal of biological chemistry 20101001

• Cys palmitoylation of the beta subunit modulates gating of the epithelial sodium channel.

  The Journal of biological chemistry 20101001

• Estrogen regulates amiloride-binding protein 1 through CCAAT/enhancer-binding protein-beta in mouse uterus during embryo implantation and decidualization.

  Endocrinology 20101001

• Angiotensin II enhances connecting tubule glomerular feedback.

  Hypertension (Dallas, Tex. : 1979) 20101001

• The acute administration of either amiloride or captopril does not prevent endothelial dysfunction induced by ischemia and reperfusion in the human forearm vasculature.

  Canadian journal of physiology and pharmacology 20101001

• Fidelity variants of RNA dependent RNA polymerases uncover an indirect, mutagenic activity of amiloride compounds.

  PLoS pathogens 20101001

• Inhibition of Na(+)/H(+) exchanger 1 by 5-(N-ethyl-N-isopropyl) amiloride reduces hypoxia-induced hepatocellular carcinoma invasion and motility.

  Cancer letters 20100928

• Epidermal nevus syndrome associated with hypophosphatemic rickets.

  Dermatology online journal 20100915

• Simultaneous determination of atenolol, chlorthalidone and amiloride in pharmaceutical preparations by capillary zone electrophoresis with ultraviolet detection.

  Biomedical chromatography : BMC 20100901

• Simultaneous determination of atenolol and amiloride in pharmaceutical preparations by capillary zone electrophoresis with capacitively coupled contactless conductivity detection.

  Biomedical chromatography : BMC 20100901

• The small molecule phenamil is a modulator of adipocyte differentiation and PPARgamma expression.

  Journal of lipid research 20100901

• Existence and distinction of acid-evoked currents in rat astrocytes.

  Glia 20100901

• Substrate specificity of Rhbg: ammonium and methyl ammonium transport.

  American journal of physiology. Cell physiology 20100901

• Pharmacological profiles of the murine gastric and colonic H,K-ATPases.

  Biochimica et biophysica acta 20100901

• Larvae of the midge Chironomus riparius possess two distinct mechanisms for ionoregulation in response to ion-poor conditions.

  American journal of physiology. Regulatory, integrative and comparative physiology 20100901

• Cellular entry of ebola virus involves uptake by a macropinocytosis-like mechanism and subsequent trafficking through early and late endosomes.

  PLoS pathogens 20100901

• [Comparison of mechanisms and cellular uptake of cell-penetrating peptide on different cell lines].

  Yao xue xue bao = Acta pharmaceutica Sinica 20100901

• Protein kinase D1 modulates aldosterone-induced ENaC activity in a renal cortical collecting duct cell line.

  Molecular and cellular endocrinology 20100830

• Enhancement in fluorescence response by a quencher for amiloride upon binding to thymine opposite an abasic site in a DNA duplex.

  Analytica chimica acta 20100818

• Interleukin-6 stimulates epithelial sodium channels in mouse cortical collecting duct cells.

  American journal of physiology. Regulatory, integrative and comparative physiology 20100801

• Measurement of airway ion transport assists the diagnosis of cystic fibrosis.

  Pediatric pulmonology 20100801

• The effects of amiloride, a Na+-H+ exchange inhibitor, on iliac artery stenosis after balloon injury in rabbits.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20100801

• Serotonin decreases alveolar epithelial fluid transport via a direct inhibition of the epithelial sodium channel.

  American journal of respiratory cell and molecular biology 20100701

• Ouabain stimulates Na-K-ATPase through a sodium/hydrogen exchanger-1 (NHE-1)-dependent mechanism in human kidney proximal tubule cells.

  American journal of physiology. Renal physiology 20100701

• Effects of central sodium on epithelial sodium channels in rat brain.

  American journal of physiology. Regulatory, integrative and comparative physiology 20100701

• Amiloride reduces the sweet taste intensity by inhibiting the human sweet taste receptor.

  Biochemical and biophysical research communications 20100625

• H2O2 and cytosolic Ca2+ signals triggered by the PM H-coupled transport system mediate K+/Na+ homeostasis in NaCl-stressed Populus euphratica cells.

  Plant, cell & environment 20100601

• Pleural electrophysiology alterations in spontaneous pneumothorax patients.

  Interactive cardiovascular and thoracic surgery 20100601

• Acid-induced CGRP release from the stomach does not depend on TRPV1 or ASIC3.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20100601

• Non-genomic rapid inhibition of Na+/H+-exchange 1 and apoptotic immunosuppression in human T cells by glucocorticoids.

  Journal of cellular physiology 20100601

• COMMD1 downregulates the epithelial sodium channel through Nedd4-2.

  American journal of physiology. Renal physiology 20100601

• Effect of the bases flanking an abasic site on the recognition of nucleobase by amiloride.

  Biochimica et biophysica acta 20100601

• Amiloride reduces portal hypertension in rat liver cirrhosis.

  Gut 20100601

• ENaC-mediated effects assessed by MRI in a rat model of hypertonic saline-induced lung hydration.

  British journal of pharmacology 20100601

• Functional studies of acid transporter in cultured rat epididymal cell.

  Fertility and sterility 20100515

• A role for Na+/H+ exchangers and intracellular pH in regulating vitamin C-driven electron transport across the plasma membrane.

  The Biochemical journal 20100513

• The amiloride-sensitive epithelial Na+ channel PPK28 is essential for drosophila gustatory water reception.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100505

• The Na+-dependent chloride-bicarbonate exchanger SLC4A8 mediates an electroneutral Na+ reabsorption process in the renal cortical collecting ducts of mice.

  The Journal of clinical investigation 20100503

• Severe respiratory phenotype caused by a de novo Arg528Gly mutation in the CACNA1S gene in a patient with hypokalemic periodic paralysis.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20100501

• Insulin alters the permeability of sheep pleura.

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20100501

• Functional characterization of a ClC-2-like Cl(-) conductance in surface epithelial cells of rat rectal colon.

  The Journal of membrane biology 20100501

• [Effect of terbutaline on sodium transport in alveolar type I and type II cells].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20100501

• [Identification of a new target for thiazidic diuretics in kidney].

  Medecine sciences : M/S 20100501

• Na+-Ca2+ exchanger contributes to Ca2+ extrusion in ATP-stimulated endothelium of intact rat aorta.

  Biochemical and biophysical research communications 20100423

• Three homologous subunits form a high affinity peptide-gated ion channel in Hydra.

  The Journal of biological chemistry 20100416

• Regulatory volume increase in epithelial cells isolated from the mouse fourth ventricle choroid plexus involves Na(+)-H(+) exchange but not Na(+)-K(+)-2Cl(-) cotransport.

  Brain research 20100406

• Change in intracellular pH causes the toxic Ca2+ entry via NCX1 in neuron- and glia-derived cells.

  Cellular and molecular neurobiology 20100401

• PKC mediates GnRH activation of a Na+/H+ exchanger in goldfish somatotropes.

  General and comparative endocrinology 20100401

• Inhibitory effects of amiloride on the current mediated by native GABA(A) receptors in cultured neurons of rat inferior colliculus.

  Clinical and experimental pharmacology & physiology 20100401

• Voltage-dependent calcium and chloride currents in S17 bone marrow stromal cell line.

  Journal of cellular physiology 20100401

• EGF and its related growth factors mediate sodium transport in mpkCCDc14 cells via ErbB2 (neu/HER-2) receptor.

  Journal of cellular physiology 20100401

• AE2 Cl-/HCO3- exchanger is required for normal cAMP-stimulated anion secretion in murine proximal colon.

  American journal of physiology. Gastrointestinal and liver physiology 20100401

• Amiloride docking to acid-sensing ion channel-1.

  The Journal of biological chemistry 20100326

• Hymenolepis diminuta: Effect of infection on ion transport in colon and blood picture of rats.

  Experimental parasitology 20100301

• Effects of arginine vasotocin and mesotocin on the activation and development of amiloride-blockable short-circuit current across larval, adult, and cultured larval bullfrog skins.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20100301

• Modulation of epithelial sodium channel activity by lipopolysaccharide in alveolar type II cells: involvement of purinergic signaling.

  American journal of physiology. Lung cellular and molecular physiology 20100301

• Calcium transport and homeostasis in gill cells of a freshwater crab Dilocarcinus pagei.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20100301

• The lectin-like domain of tumor necrosis factor improves lung function after rat lung transplantation--potential role for a reduction in reactive oxygen species generation.

  Critical care medicine 20100301

• Attenuation of pulmonary arterial smooth muscle cell proliferation following hypoxic pulmonary hypertension by the Na+/H+ exchange inhibitor amiloride.

  The Chinese journal of physiology 20100227

• Chemoreceptor hypersensitivity, sympathetic excitation, and overexpression of ASIC and TASK channels before the onset of hypertension in SHR.

  Circulation research 20100219

• A novel application of immobilization on membranes for the separation and spectrofluorimetric quantification of amiloride and furosemide in pharmaceutical samples.

  Analytica chimica acta 20100219

• A new stretch for muscle spindle research.

  The Journal of physiology 20100215

• Lipopolysaccharide modifies amiloride-sensitive Na+ transport processes across human airway cells: role of mitogen-activated protein kinases ERK 1/2 and 5.

  Pflugers Archiv : European journal of physiology 20100201

• Intracellular pH regulation in isolated trout gill mitochondrion-rich (MR) cell subtypes: evidence for Na+/H+ activity.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20100201

• Modulation of urea transport across sheep rumen epithelium in vitro by SCFA and CO2.

  American journal of physiology. Gastrointestinal and liver physiology 20100201

• Ammonium-dependent sodium uptake in mitochondrion-rich cells of medaka (Oryzias latipes) larvae.

  American journal of physiology. Cell physiology 20100201

• Role of epithelial sodium channels in the renal myogenic response?

  Hypertension (Dallas, Tex. : 1979) 20100201

• Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells.

  The Journal of clinical investigation 20100201

• Epithelial Na+ channels derived from human lung are activated by shear force.

  Respiratory physiology & neurobiology 20100131

• Blood pressure lowering efficacy of potassium-sparing diuretics (that block the epithelial sodium channel) for primary hypertension.

  The Cochrane database of systematic reviews 20100120

• Increase of beta-endorphin secretion by agmatine is induced by activation of imidazoline I(2A) receptors in adrenal gland of rats.

  Neuroscience letters 20100114

• A novel mutation in the AVPR2 gene (222delA) associated with X-linked nephrogenic diabetes insipidus in a boy with growth failure.

  Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20100101

• The epithelial sodium channel (ENaC): Mediator of the aldosterone response in the vascular endothelium?

  Steroids 20100101

• Effects of extracellular pH reductions on [(3)H]D-aspartate and [(3)H]noradrenaline release by presynaptic nerve terminals isolated from rat cerebral cortex.

  Journal of neural transmission (Vienna, Austria : 1996) 20100101

• Basophil activation in two cases of hydrochlorothiazide-induced noncardiogenic pulmonary edema.

  Allergy 20100101

• Cell volume decrease as a link between azaspiracid-induced cytotoxicity and c-Jun-N-terminal kinase activation in cultured neurons.

  Toxicological sciences : an official journal of the Society of Toxicology 20100101

• Long-term terbutaline exposure stimulates alpha1-Na+-K+-ATPase expression at posttranscriptional level in rat fetal distal lung epithelial cells.

  American journal of physiology. Lung cellular and molecular physiology 20100101

• ANP-mediated inhibition of distal nephron fractional sodium reabsorption in wild-type and mice overexpressing natriuretic peptide receptor.

  American journal of physiology. Renal physiology 20100101

• Can Burkholderia cepacia complex be eradicated with nebulised amiloride and TOBI?

  Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 20100101

• A unique modulator of endoplasmic reticulum stress-signalling pathways: the novel pharmacological properties of amiloride in glial cells.

  British journal of pharmacology 20100101

• The vacuolar-type H-ATPase in ovine rumen epithelium is regulated by metabolic signals.

  Journal of biomedicine & biotechnology 20100101

• Hsp60 is actively secreted by human tumor cells.

  PloS one 20100101

• Modulation of neuroprotective effect of ischemic post-conditioning by dichlorobenzamil a Na(+)/Ca(2+) exchanger inhibitor in mice.

  Biological & pharmaceutical bulletin 20100101

• A clathrin independent macropinocytosis-like entry mechanism used by bluetongue virus-1 during infection of BHK cells.

  PloS one 20100101

• The effect of topical amiloride eye drops on tear quantity in rabbits.

  Molecular vision 20100101

• Analysis of blocker-labeled channels reveals the dependence of recycling rates of ENaC on the total amount of recycled channels.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101

• Activation of imidazoline I(2B) receptors by guanidine to increase glucose uptake in skeletal muscle of rats.

  Neuroscience letters 20091225

• Carbon monoxide rapidly impairs alveolar fluid clearance by inhibiting epithelial sodium channels.

  American journal of respiratory cell and molecular biology 20091201

• Effect of canrenone and amiloride on the prooxidative effect induced by aldosterone in human mononuclear leukocytes in vitro.

  Journal of endocrinological investigation 20091201

• Actions of antidiuretic hormone analogues on intact and nystatin-permeabilized frog skins.

  Experimental physiology 20091201

• Airway surface liquid depth measured in ex vivo fragments of pig and human trachea: dependence on Na+ and Cl- channel function.

  American journal of physiology. Lung cellular and molecular physiology 20091201

• Stimulation by sparkling water of gastroduodenal HCO3- secretion in rats.

  Medical science monitor : international medical journal of experimental and clinical research 20091201

• [Chronic renal complications induced by lithium].

  L'Encephale 20091201

• Characterization of a calcitonin gene-related peptide release assay in rat isolated distal colon.

  Archives of pharmacal research 20091201

• Influenza virus M2 protein inhibits epithelial sodium channels by increasing reactive oxygen species.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20091101

• Characteristics of Cl- uptake in rat alveolar type I cells.

  American journal of physiology. Lung cellular and molecular physiology 20091101

• pH regulating transporters in neurons from various chemosensitive brainstem regions in neonatal rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20091101

• Yes, no, maybe so: ENaC proteins as mediators of renal myogenic constriction.

  Hypertension (Dallas, Tex. : 1979) 20091101

• Effect of epithelial sodium channel blockade on the myogenic response of rat juxtamedullary afferent arterioles.

  Hypertension (Dallas, Tex. : 1979) 20091101

• [Antisense oligonucleotides for therapy of cystic fibrosis. Inhibition of sodium absorption mediated by ENaC in nasal epithelial cells].

  HNO 20091101

• Bicarbonate transport by the human pancreatic ductal cell line HPAF.

  Pancreas 20091101

• The effect of different kinds of electrolyte and non-electrolyte solutions on the survival rate and morphology of zebrafish Danio rerio embryos.

  Journal of fish biology 20091101

• Acid-sensing ionic-channel functional expression in the vestibular endorgans.

  Neuroscience letters 20091009

• Acetylcholine synthesis and release in NIH3T3 cells coexpressing the high-affinity choline transporter and choline acetyltransferase.

  Journal of neuroscience research 20091001

• Molecular pharmacology of the amiloride analog 3-amino-6-chloro-5-[(4-chloro-benzyl)amino]-n-[[(2,4-dimethylbenzyl)-amino]iminomethyl]-pyrazinecarboxamide (CB-DMB) as a pan inhibitor of the Na+-Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in stably transfected cells.

  The Journal of pharmacology and experimental therapeutics 20091001

• Lipopolysaccharide directly alters renal tubule transport through distinct TLR4-dependent pathways in basolateral and apical membranes.

  American journal of physiology. Renal physiology 20091001

• Dysfunctional cystic fibrosis transmembrane conductance regulator inhibits phagocytosis of apoptotic cells with proinflammatory consequences.

  American journal of physiology. Lung cellular and molecular physiology 20091001

• Sodium transport in the choroid plexus and salt-sensitive hypertension.

  Hypertension (Dallas, Tex. : 1979) 20091001

• Attenuation of peripheral salt taste responses and local immune function contralateral to gustatory nerve injury: effects of aldosterone.

  American journal of physiology. Regulatory, integrative and comparative physiology 20091001

• Effect of ventilation pressure on alveolar fluid clearance and beta-agonist responses in mice.

  American journal of physiology. Lung cellular and molecular physiology 20091001

• Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

  Nature chemical biology 20091001

• Update in primary aldosteronism.

  The Journal of clinical endocrinology and metabolism 20091001

• Na(+)/H(+) antiporter activity of the SOS1 gene: lifetime imaging analysis and electrophysiological studies on Arabidopsis seedlings.

  Physiologia plantarum 20091001

• Developmental change of Na(+)-absorptive function in Reissner's membrane epithelia.

  Neuroreport 20090923

• Nephrogenic diabetes insipidus: treat with caution.

  Pediatric nephrology (Berlin, Germany) 20090901

• Benzamil prevents brain water accumulation in hyponatraemic rats.

  Acta neurochirurgica 20090901

• Ca(2+) regulation of endocochlear potential in marginal cells.

  The journal of physiological sciences : JPS 20090901

• Protein transport in human cells mediated by covalently and noncovalently conjugated arginine-rich intracellular delivery peptides.

  Peptides 20090901

• Pleural electrophysiology variations according to location in pleural cavity.

  Interactive cardiovascular and thoracic surgery 20090901

• Regulation of the benzamil-insensitive salt taste receptor by intracellular Ca2+, protein kinase C, and calcineurin.

  Journal of neurophysiology 20090901

• Characterization of acid-sensing ion channels in medium spiny neurons of mouse striatum.

  Neuroscience 20090804

• Blockade of epithelial sodium channels improves sperm motility in asthenospermia patients.

  International journal of andrology 20090801

• Role of the sodium hydrogen exchanger in maitotoxin-induced cell death in cultured rat cortical neurons.

  Toxicon : official journal of the International Society on Toxinology 20090801

• K+ secretion in the rat kidney: Na+ channel-dependent and -independent mechanisms.

  American journal of physiology. Renal physiology 20090801

• ASIC1 contributes to pulmonary vascular smooth muscle store-operated Ca(2+) entry.

  American journal of physiology. Lung cellular and molecular physiology 20090801

• A novel amiloride-sensitive h+ transport pathway mediates enhanced superoxide production in thick ascending limb of salt-sensitive rats, not na+/h+ exchange.

  Hypertension (Dallas, Tex. : 1979) 20090801

• Role of the C-terminal part of the extracellular domain of the alpha-ENaC in activation by sulfonylurea glibenclamide.

  The Journal of membrane biology 20090801

• [Can a lithium-induced polyuria be treated with an amiloride / hydrochlorothiazide combination? ].

  Medizinische Monatsschrift fur Pharmazeuten 20090801

• [Fast nongenomic aldosterone effect on the kinetics of intracellular sodium and cell volume in the cortical part of collecting ducts of the rat kidney].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20090801

• Response of mechanosensory hair cells of the zebrafish lateral line to aminoglycosides reveals distinct cell death pathways.

  Hearing research 20090701

• Amiloride blocks lithium entry through the sodium channel thereby attenuating the resultant nephrogenic diabetes insipidus.

  Kidney international 20090701

• Elevated hydrostatic pressure activates sodium/hydrogen exchanger-1 in rat optic nerve head astrocytes.

  American journal of physiology. Cell physiology 20090701

• Acid-sensing ion channels contribute to the metaboreceptor component of the exercise pressor reflex.

  American journal of physiology. Heart and circulatory physiology 20090701

• Structure and inhibition of the SARS coronavirus envelope protein ion channel.

  PLoS pathogens 20090701

• In situ measurement of airway surface liquid [K+] using a ratioable K+-sensitive fluorescent dye.

  The Journal of biological chemistry 20090605

• The cystic fibrosis transmembrane conductance regulator and chloride-dependent ion fluxes of ovine vocal fold epithelium.

  Journal of speech, language, and hearing research : JSLHR 20090601

• Human salt taste and the lingual surface potential correlate.

  Chemical senses 20090601

• Ion transport across CF and normal murine olfactory and ciliated epithelium.

  American journal of physiology. Cell physiology 20090601

• Characterization of mouse alveolar epithelial cell monolayers.

  American journal of physiology. Lung cellular and molecular physiology 20090601

• The mechanosensitive cell line ND-C does not express functional thermoTRP channels.

  Neuropharmacology 20090601

• Regulation of epithelial sodium channels by cGMP/PKGII.

  The Journal of physiology 20090601

• Nhe1 is a luminal Na+/H+ exchanger in mouse choroid plexus and is targeted to the basolateral membrane in Ncbe/Nbcn2-null mice.

  American journal of physiology. Cell physiology 20090601

• Neurotensin signaling induces intracellular alkalinization and interleukin-8 expression in human pancreatic cancer cells.

  Molecular oncology 20090601

• Endothelial epithelial sodium channel inhibition activates endothelial nitric oxide synthase via phosphoinositide 3-kinase/Akt in small-diameter mesenteric arteries.

  Hypertension (Dallas, Tex. : 1979) 20090601

• Cellular calcium deficiency plays a role in neuronal death caused by proteasome inhibitors.

  Journal of neurochemistry 20090601

• Electrophysiological characterization of electrolyte and nutrient transport across the small intestine in horses.

  Journal of animal physiology and animal nutrition 20090601

• Bacterial endotoxin enhances colorectal cancer cell adhesion and invasion through TLR-4 and NF-kappaB-dependent activation of the urokinase plasminogen activator system.

  British journal of cancer 20090519

• Functional identification of a novel transport system for endogenous and synthetic opioid peptides in the rabbit conjunctival epithelial cell line CJVE.

  Pharmaceutical research 20090501

• Expression and regulation of epithelial Na+ channels by nucleotides in pleural mesothelial cells.

  American journal of respiratory cell and molecular biology 20090501

• Amiloride inhibits hydrogen peroxide-induced Ca2+ responses in human CNS pericytes.

  Microvascular research 20090501

• Amiloride derived inhibitors of acid-sensing ion channel-3 (ASIC3).

  Bioorganic & medicinal chemistry letters 20090501

• Dimethyl amiloride, a Na+-H+ exchange inhibitor, and its cardioprotective effects in hemorrhagic shock in in vivo resuscitated rats.

  The journal of physiological sciences : JPS 20090501

• Low [NaCl]-induced neuronal nitric oxide synthase (nNOS) expression and NO generation are regulated by intracellular pH in a mouse macula densa cell line (NE-MD).

  The journal of physiological sciences : JPS 20090501

• Expression and function of Na+/Ca2+ exchangers 1 and 3 in human macrophages and monocytes.

  European journal of immunology 20090501

• TRPV1 controls acid- and heat-induced calcitonin gene-related peptide release and sensitization by bradykinin in the isolated mouse trachea.

  The European journal of neuroscience 20090501

• Identification of the Na+/H+ exchanger 1 in dorsal root ganglion and spinal cord: its possible role in inflammatory nociception.

  Neuroscience 20090421

• Acid-sensing ion channels in neurones of the rat suprachiasmatic nucleus.

  The Journal of physiology 20090415

• Functional ENaC channels expressed in endothelial cells: a new candidate for mediating shear force.

  Microcirculation (New York, N.Y. : 1994) 20090401

• Amiloride derivatives induce apoptosis by depleting ER Ca(2+) stores in vascular endothelial cells.

  British journal of pharmacology 20090401

• Studies on cerebral protection of digoxin against ischemia/reperfusion injury in mice.

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20090401

• The regulation of amiloride-sensitive epithelial sodium channels by tumor necrosis factor-alpha in injured lungs and alveolar type II cells.

  Respiratory physiology & neurobiology 20090331

• NaCl responsive taste cells in the mouse fungiform taste buds.

  Neuroscience 20090317

• Update in cystic fibrosis 2008.

  American journal of respiratory and critical care medicine 20090315

• Inhibitions of chloride transport and gap junction reduce fluid flow across the whole porcine ciliary epithelium.

  Investigative ophthalmology & visual science 20090301

• Acid sensing ion channel (ASIC) inhibitors exhibit anxiolytic-like activity in preclinical pharmacological models.

  Psychopharmacology 20090301

• The Na+/H+ exchanger modulates long-term potentiation in rat hippocampal slices.

  Naunyn-Schmiedeberg's archives of pharmacology 20090301

• Mechanisms in the PVN mediating local and central sodium-induced hypertension in Wistar rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20090301

• SARS-CoV proteins decrease levels and activity of human ENaC via activation of distinct PKC isoforms.

  American journal of physiology. Lung cellular and molecular physiology 20090301

• Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters.

  American journal of physiology. Cell physiology 20090301

• Regulation of ENaC-mediated sodium transport by glucocorticoids in Reissner's membrane epithelium.

  American journal of physiology. Cell physiology 20090301

• The long-term follow-up after idiosyncratic drug-induced liver injury with jaundice.

  Journal of hepatology 20090301

• Stimulation of large-conductance Ca2+-activated K+ channels by the Na+/Ca2+ exchanger inhibitor dichlorobenzamil in cultured human umbilical vein endothelial cells and mouse aortic smooth muscle cells.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20090301

• Stimulation of alpha(1)-adrenoceptors reduces glutamatergic synaptic input from primary afferents through GABA(A) receptors and T-type Ca(2+) channels.

  Neuroscience 20090218

• Why did the NHE inhibitor clinical trials fail?

  Journal of molecular and cellular cardiology 20090201

• NaCl-induced alternations of cellular and tissue ion fluxes in roots of salt-resistant and salt-sensitive poplar species.

  Plant physiology 20090201

• Nociceptin/orphanin FQ peptide receptor agonist Ac-RYYRWKKKKKKK-NH2 (ZP120) induces antinatriuresis in rats by stimulation of amiloride-sensitive sodium reabsorption.

  The Journal of pharmacology and experimental therapeutics 20090201

• Functional coupling of the downregulated in adenoma Cl-/base exchanger DRA and the apical Na+/H+ exchangers NHE2 and NHE3.

  American journal of physiology. Gastrointestinal and liver physiology 20090201

• Role of the amiloride-sensitive epithelial Na+ channel in the pathogenesis and as a therapeutic target for cystic fibrosis lung disease.

  Experimental physiology 20090201

• Plasmin in nephrotic urine activates the epithelial sodium channel.

  Journal of the American Society of Nephrology : JASN 20090201

• Interleukin-17A induces bicarbonate secretion in normal human bronchial epithelial cells.

  American journal of physiology. Lung cellular and molecular physiology 20090201

• Acid increases inflammatory pain in rats: effect of local peripheral ASICs inhibitors.

  European journal of pharmacology 20090128

• Amiloride enhances the anticonvulsant action of various antiepileptic drugs in the mouse maximal electroshock seizure model.

  Journal of neural transmission (Vienna, Austria : 1996) 20090101

• Membrane transporters and cytoplasmatic pH regulation on bovine Sertoli cells.

  The Journal of membrane biology 20090101

• Hydrogen peroxide mobilizes Ca2+ through two distinct mechanisms in rat hepatocytes.

  Acta pharmacologica Sinica 20090101

• The effect of endothelin-1 on alveolar fluid clearance and pulmonary edema formation in the rat.

  Anesthesia and analgesia 20090101

• Identification of antihypertensive drugs which inhibit amyloid-beta protein oligomerization.

  Journal of Alzheimer's disease : JAD 20090101

• Diuretics.

  British journal of hospital medicine (London, England : 2005) 20090101

• Comparison of vectorial ion transport in primary murine airway and human sinonasal air-liquid interface cultures, models for studies of cystic fibrosis, and other airway diseases.

  American journal of rhinology & allergy 20090101

• Development and validation of a reversed-phase high-performance liquid chromatographic method for the simultaneous determination of amiloride hydrochloride, atenolol, hydrochlorothiazide, and chlorthalidone in their combined mixtures.

  Journal of AOAC International 20090101

• Development and validation of an LC method for simultaneous determination of amiloride hydrochloride and hydrochlorothiazide in human urine.

  Journal of AOAC International 20090101

• Transduction of the MPG-tagged fusion protein into mammalian cells and oocytes depends on amiloride-sensitive endocytic pathway.

  BMC biotechnology 20090101

• Involvement of phosphatidylinositol kinases in the effect of oxidized glutathione and drug glutoxim on Na+ transport in frog skin.

  Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20090101

• Ionic support of the cough reflex.

  Annales Academiae Medicae Stetinensis 20090101

• Preventive but not late amiloride therapy reduces morbidity and mortality of lung disease in betaENaC-overexpressing mice.

  American journal of respiratory and critical care medicine 20081215

• Amiloride: still a viable treatment option in cystic fibrosis?

  American journal of respiratory and critical care medicine 20081215

• Epithelial Na+ channel delta subunit is an acid sensor in the human oesophagus.

  European journal of pharmacology 20081214

• CO2 chemosensing in rat oesophagus.

  Gut 20081201

• Initiation of motility by steelhead (Oncorhynchus mykiss) sperm: membrane ion exchangers and pH sensitivity.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20081201

• Behavioral and electrophysiological taste responses change after brief or prolonged dietary sodium deprivation.

  American journal of physiology. Regulatory, integrative and comparative physiology 20081201

• Transport of lithium across the lamprey (Lampetra fluviatilis) erythrocyte membrane.

  General physiology and biophysics 20081201

• Simultaneous measurement of mechanical responses and transepithelial potential difference and resistance, in guinea-pig isolated, perfused trachea using a novel apparatus: pharmacological characterization.

  European journal of pharmacology 20081119

• Deubiquitylation regulates activation and proteolytic cleavage of ENaC.

  Journal of the American Society of Nephrology : JASN 20081101

• A mathematical model of distal nephron acidification: diuretic effects.

  American journal of physiology. Renal physiology 20081101

• AICAR decreases the activity of two distinct amiloride-sensitive Na+-permeable channels in H441 human lung epithelial cell monolayers.

  American journal of physiology. Lung cellular and molecular physiology 20081101

• Activation of Na+/H+ and K+/H+ exchange by calyculin A in Amphiuma tridactylum red blood cells: implications for the control of volume-induced ion flux activity.

  American journal of physiology. Cell physiology 20081101

• Inhibition of Na+/H+ exchanger enhances low pH-induced L-selectin shedding and beta2-integrin surface expression in human neutrophils.

  American journal of physiology. Cell physiology 20081101

• Increased reabsorption of alveolar edema fluid in the obese Zucker rat.

  The Tohoku journal of experimental medicine 20081101

• Blocking acid-sensing ion channel 1 alleviates Huntington's disease pathology via an ubiquitin-proteasome system-dependent mechanism.

  Human molecular genetics 20081015

• Intracellular sodium regulates proteolytic activation of the epithelial sodium channel.

  The Journal of biological chemistry 20081010

• Trypsin can activate the epithelial sodium channel (ENaC) in microdissected mouse distal nephron.

  American journal of physiology. Renal physiology 20081001

• Vasopressin acts on platelets to generate procoagulant activity.

  Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20081001

• Blood pressure-lowering efficacy of amiloride versus enalapril as add-on drugs in patients with uncontrolled blood pressure receiving hydrochlorothiazide.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20081001

• Voltage-dependent anion channels (VDAC) in the plasma membrane play a critical role in apoptosis in differentiated hippocampal neurons but not in neural stem cells.

  Cell cycle (Georgetown, Tex.) 20081001

• Seizures and sodium hydrogen exchangers: potential of sodium hydrogen exchanger inhibitors as novel anticonvulsants.

  CNS & neurological disorders drug targets 20081001

• Study of the photolytic and photocatalytic transformation of amiloride in water.

  Journal of pharmaceutical and biomedical analysis 20080929

• pH dependent efflux of methamphetamine derivatives and their reversal through human Caco-2 cell monolayers.

  European journal of pharmacology 20080911

• Dorsal root ganglion neurons innervating skeletal muscle respond to physiological combinations of protons, ATP, and lactate mediated by ASIC, P2X, and TRPV1.

  Journal of neurophysiology 20080901

• Enhanced amiloride-sensitive superoxide production in renal medullary thick ascending limb of Dahl salt-sensitive rats.

  American journal of physiology. Renal physiology 20080901

• Lithium-induced nephrogenic diabetes insipidus: renal effects of amiloride.

  Clinical journal of the American Society of Nephrology : CJASN 20080901

• Acid-sensing ion and epithelial sodium channels do not contribute to the mechanoreceptor component of the exercise pressor reflex.

  American journal of physiology. Heart and circulatory physiology 20080901

• Effect of Maillard reacted peptides on human salt taste and the amiloride-insensitive salt taste receptor (TRPV1t).

  Chemical senses 20080901

• Amiloride is neuroprotective in an MPTP model of Parkinson's disease.

  Neurobiology of disease 20080901

• Luminal hydrochloric acid stimulates rapid transepithelial ion fluxes in rodent esophageal stratified squamous epithelium.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080901

• Epithelial Na+ channel delta subunit mediates acid-induced ATP release in the human skin.

  Biochemical and biophysical research communications 20080815

• Novel and selective potentiometric membrane sensor for amiloride determination in pharmaceutical compounds and urine.

  Journal of pharmaceutical and biomedical analysis 20080805

• Transport activities involved in intracellular pH recovery following acid and alkali challenges in rat brain microvascular endothelial cells.

  Pflugers Archiv : European journal of physiology 20080801

• Human parietal pleura present electrophysiology variations according to location in pleural cavity.

  Interactive cardiovascular and thoracic surgery 20080801

• Late expression of Na+/H+ exchanger 1 (NHE1) and neuroprotective effects of NHE inhibitor in the gerbil hippocampal CA1 region induced by transient ischemia.

  Experimental neurology 20080801

• In vitro interactions of tobramycin with various nonantibiotics against Pseudomonas aeruginosa and Burkholderia cenocepacia.

  FEMS microbiology letters 20080801

• Increased colonic sodium absorption in rats with chronic renal failure is partially mediated by AT1 receptor agonism.

  American journal of physiology. Gastrointestinal and liver physiology 20080801

• Efficient MHC class I presentation by controlled intracellular trafficking of antigens in octaarginine-modified liposomes.

  Molecular therapy : the journal of the American Society of Gene Therapy 20080801

• Reduction in systemic epithelial ion transport in septicemia-related pulmonary edema due to changes in amiloride-insensitive sodium transport?

  American journal of physiology. Lung cellular and molecular physiology 20080801

• Amiloride delays the onset of pilocarpine-induced seizures in rats.

  Brain research 20080730

• Evidence for postsynaptic modulation of muscle contraction by a Drosophila neuropeptide.

  Peptides 20080701

• Ouabain-induced stimulation of sodium-hydrogen exchange in rat optic nerve astrocytes.

  American journal of physiology. Cell physiology 20080701

• Internalization of a non-pathogenic mycobacteria by macropinocytosis in human alveolar epithelial A549 cells.

  Microbial pathogenesis 20080701

• Effects of amiloride, benzamil, and alterations in extracellular Na+ on the rat afferent arteriole and its myogenic response.

  American journal of physiology. Renal physiology 20080701

• Functional characterization of acid-sensing ion channels in cultured neurons of rat inferior colliculus.

  Neuroscience 20080623

• Ameliorative effects of amiloride and pralidoxime in chronic constriction injury and vincristine induced painful neuropathy in rats.

  European journal of pharmacology 20080610

• Activation of chloride secretion via proteinase-activated receptor 2 in a human eccrine sweat gland cell line--NCL-SG3.

  Experimental dermatology 20080601

• Effects of hexosamines and omega-3/omega-6 fatty acids on pH regulation by interleukin 1-treated isolated bovine articular chondrocytes.

  Pflugers Archiv : European journal of physiology 20080601

• Parallel improvement of sodium and chloride transport defects by miglustat (n-butyldeoxynojyrimicin) in cystic fibrosis epithelial cells.

  The Journal of pharmacology and experimental therapeutics 20080601

• Amiloride derivatives and a nonpeptidic antagonist bind at two distinct allosteric sites in the human gonadotropin-releasing hormone receptor.

  Molecular pharmacology 20080601

• Mouse model of type II Bartter's syndrome. I. Upregulation of thiazide-sensitive Na-Cl cotransport activity.

  American journal of physiology. Renal physiology 20080601

• Dimethyl amiloride improves glucose homeostasis in mouse models of type 2 diabetes.

  American journal of physiology. Endocrinology and metabolism 20080601

• An optimized recording method to characterize biophysical and pharmacological properties of acid-sensing ion channel.

  Neuroscience bulletin 20080601

• Epithelial sodium channel in a human trophoblast cell line (BeWo).

  The Journal of membrane biology 20080601

• [Glucose-6-phosphatase from nuclear envelope in rat liver].

  Investigacion clinica 20080601

• Small molecule activator of the human epithelial sodium channel.

  The Journal of biological chemistry 20080502

• Chronic candesartan alters expression and activity of NKCC2, NCC, and ENaC in the obese Zucker rat.

  American journal of physiology. Renal physiology 20080501

• The regulation of selective and nonselective Na+ conductances in H441 human airway epithelial cells.

  American journal of physiology. Lung cellular and molecular physiology 20080501

• ACh-induced depolarization in inner ear artery is generated by activation of a TRP-like non-selective cation conductance and inactivation of a potassium conductance.

  Hearing research 20080501

• Formation of a new receptor-operated channel by heteromeric assembly of TRPP2 and TRPC1 subunits.

  EMBO reports 20080501

• Cerebral microvascular nNOS responds to lowered oxygen tension through a bumetanide-sensitive cotransporter and sodium-calcium exchanger.

  American journal of physiology. Heart and circulatory physiology 20080501

• A role for benzamil-sensitive proteins of the central nervous system in the pathogenesis of salt-dependent hypertension.

  Clinical and experimental pharmacology & physiology 20080501

• Lidocaine increases intracellular sodium concentration through a Na+-H+ exchanger in an identified Lymnaea neuron.

  Anesthesia and analgesia 20080501

• A mathematical model of the proton balance in the outer mantle epithelium of Anodonta cygnea L.

  The Journal of membrane biology 20080501

• Cellular uptake of cell-penetrating peptides pVEC and transportan in plants.

  Journal of peptide science : an official publication of the European Peptide Society 20080401

• Amiloride restores renal medullary osmolytes in lithium-induced nephrogenic diabetes insipidus.

  American journal of physiology. Renal physiology 20080401

• Sodium-dependent regulation of renal amiloride-sensitive currents by apical P2 receptors.

  Journal of the American Society of Nephrology : JASN 20080401

• Role of NHE1 in calcium signaling and cell proliferation in human CNS pericytes.

  American journal of physiology. Heart and circulatory physiology 20080401

• Aortas isolated from sinoaortic-denervated rats exhibit rhythmic contractions that are regulated by pharmacologically distinct calcium sources.

  Basic & clinical pharmacology & toxicology 20080401

• Preferential assembly of epithelial sodium channel (ENaC) subunits in Xenopus oocytes: role of furin-mediated endogenous proteolysis.

  The Journal of biological chemistry 20080321

• Hypotonic stimuli enhance proton-gated currents of acid-sensing ion channel-1b.

  Biochemical and biophysical research communications 20080314

• Adduction of amiloride hydrochloride in urea through a modified technique for the dissolution enhancement.

  Journal of pharmaceutical sciences 20080301

• Impaired acid secretion in cortical collecting duct intercalated cells from H-K-ATPase-deficient mice: role of HKalpha isoforms.

  American journal of physiology. Renal physiology 20080301

• Oxidative stress and the genomic regulation of aldosterone-stimulated NHE1 activity in SHR renal proximal tubular cells.

  Molecular and cellular biochemistry 20080301

• Amiloride-insensitive Na+ and fluid absorption in the mammalian distal lung.

  American journal of physiology. Lung cellular and molecular physiology 20080301

• Variations in ENaC subunit composition may determine amiloride sensitivity and beta-adrenergic stimulation of lung fluid absorption.

  American journal of physiology. Lung cellular and molecular physiology 20080301

• Comparative study on transduction and toxicity of protein transduction domains.

  British journal of pharmacology 20080301

• Presence and regulation of epithelial sodium channels in the marginal cells of stria vascularis.

  Acta oto-laryngologica 20080301

• Effect of Huoxiang-zhengqi liquid on HCO(3)(-) secretion by intact porcine distal airway epithelium.

  Sheng li xue bao : [Acta physiologica Sinica] 20080225

• Defective ENaC processing and function in tissue kallikrein-deficient mice.

  The Journal of biological chemistry 20080222

• Letter regarding article by Hood et al, 'The Spironolactone, Amiloride, Losartan, and Thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio'.

  Circulation 20080205

• Aldosterone and amiloride alter ENaC abundance in vascular endothelium.

  Pflugers Archiv : European journal of physiology 20080201

• Protection of ischaemic-reperfused rat heart by dimethylamiloride is associated with inhibition of mitochondrial permeability transition.

  Clinical and experimental pharmacology & physiology 20080201

• Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases.

  Current opinion in pharmacology 20080201

• Rapid changes in gustatory function induced by contralateral nerve injury and sodium depletion.

  Chemical senses 20080201

• Osmotic tolerance of avian spermatozoa: influence of time, temperature, cryoprotectant and membrane ion pump function on sperm viability.

  Cryobiology 20080201

• Presynaptic release probability is increased in hippocampal neurons from ASIC1 knockout mice.

  Journal of neurophysiology 20080201

• Intracellular mechanisms and receptor types for endothelin-1-induced positive and negative inotropy in mouse ventricular myocardium.

  Naunyn-Schmiedeberg's archives of pharmacology 20080201

• Fluid and osmolyte recovery in the common pond snail Lymnaea stagnalis following full-body withdrawal.

  The Journal of experimental biology 20080201

• The effect of amiloride during infusion of oxytocin in male sprague-dawley rats: a study of a possible intrarenal target site for oxytocin.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20080201

• Characterization of human ASIC2a homomeric channels stably expressed in murine Ltk- cells.

  Life sciences 20080102

• 5-(N-ethyl-N-isopropyl)-amiloride enhances SMN2 exon 7 inclusion and protein expression in spinal muscular atrophy cells.

  Annals of neurology 20080101

• Matrix metalloproteinase-9 and urokinase plasminogen activator mediate interleukin-1-induced neurotoxicity.

  Molecular and cellular neurosciences 20080101

• Amiloride-sensitive NaCl taste responses are associated with genetic variation of ENaC alpha-subunit in mice.

  American journal of physiology. Regulatory, integrative and comparative physiology 20080101

• Dietary salt enhances benzamil-sensitive component of myogenic constriction in mesenteric arteries.

  American journal of physiology. Heart and circulatory physiology 20080101

• Amiloride-sensitive channels in type I fungiform taste cells in mouse.

  BMC neuroscience 20080101

• Targeting splicing in spinal muscular atrophy.

  Annals of neurology 20080101

• Amiloride-sensitive and amiloride-insensitive kaliuresis in advanced chronic kidney disease.

  Journal of nephrology 20080101

• Development of a simplified assay for determination of the antimineralocorticoid activity of compounds dosed in rats.

  Journal of pharmacological and toxicological methods 20080101

• Mitochondrial Complex I superoxide production is attenuated by uncoupling.

  The international journal of biochemistry & cell biology 20080101

• Imaging the electric field associated with mouse and human skin wounds.

  Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20080101

• Regulation of blood pressure, natriuresis and renal thiazide/amiloride sensitivity in PPARalpha null mice.

  Blood pressure 20080101

• Nongenomic effect of aldosterone on ion transport pathways of red blood cells.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101

• Effect of disulfide-containing compounds on the Na+ transport in the frog skin.

  Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20080101

• Clathrin and LRP-1-independent constitutive endocytosis and recycling of uPAR.

  PloS one 20080101

• Troglitazone induced cytosolic acidification via extracellular signal-response kinase activation and mitochondrial depolarization: complex I proton pumping regulates ammoniagenesis in proximal tubule-like LLC-PK1 cells.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101

• Alkalinization in the isolated and perfused anterior midgut of the larval mosquito, Aedes aegypti.

  Journal of insect science (Online) 20080101

• Acid sensing ion channels 2 and 3 are required for inhibition of visceral nociceptors by benzamil.

  Pain 20071215

• Phosphatidylinositol 4-phosphate 5-kinase reduces cell surface expression of the epithelial sodium channel (ENaC) in cultured collecting duct cells.

  The Journal of biological chemistry 20071214

• Inhibition of TRPP3 channel by amiloride and analogs.

  Molecular pharmacology 20071201

• Amiloride 10 mg is less effective than spironolactone 25 mg in patients with hypertension resistant to a multidrug regime including an angiotensin-blocking agent.

  Journal of hypertension 20071201

• Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system.

  Nature medicine 20071201

• Phenylphosphonate transport by Helicobacter pylori.

  Helicobacter 20071201

• Solute diffusion through stripped mouse duodenum.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20071201

• Regulation of paracellular ion conductances by NaCl gradients in renal epithelial cells.

  Biochemical and biophysical research communications 20071123

• HCO(-3)-dependent pHi recovery and overacidification induced by NH+4 pulse in rat lung alveolar type II cells: HCO(-3)-dependent NH3 excretion from lungs?

  Pflugers Archiv : European journal of physiology 20071101

• Hydrogen peroxide stimulates chloride secretion in primary inner medullary collecting duct cells via mPGES-1-derived PGE2.

  American journal of physiology. Renal physiology 20071101

• P2Y receptor regulation of sodium transport in human mammary epithelial cells.

  American journal of physiology. Cell physiology 20071101

• Electron microprobe analysis of rabbit ciliary epithelium indicates enhanced secretion posteriorly and enhanced absorption anteriorly.

  American journal of physiology. Cell physiology 20071101

• Enhanced Na+/H+ exchange activity contributes to the pathogenesis of muscular dystrophy via involvement of P2 receptors.

  The American journal of pathology 20071101

• [Amiloride attenuates hypoxia-induced proliferation of rats pulmonary artery smooth muscle cells by suppressing Na+/ H+ exchanger-1].

  Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20071101

• Epithelial Na+ channel and ion transport in human nasal polyp and paranasal sinus mucosa.

  Biochemical and biophysical research communications 20071026

• The alpha2-adrenergic receptor agonist UK 14,304 inhibits secretin-stimulated ductal secretion by downregulation of the cAMP system in bile duct-ligated rats.

  American journal of physiology. Cell physiology 20071001

• Expression of CFTR from a ciliated cell-specific promoter is ineffective at correcting nasal potential difference in CF mice.

  Gene therapy 20071001

• Implementation of a transit compartment model for describing drug absorption in pharmacokinetic studies.

  Journal of pharmacokinetics and pharmacodynamics 20071001

• Sodium self-inhibition of human epithelial sodium channel: selectivity and affinity of the extracellular sodium sensing site.

  American journal of physiology. Renal physiology 20071001

• Localization of amiloride-sensitive sodium current and voltage-gated calcium currents in rat fungiform taste cells.

  Journal of neurophysiology 20071001

• Reduced ENaC protein abundance contributes to the lower blood pressure observed in pendrin-null mice.

  American journal of physiology. Renal physiology 20071001

• Transepithelial bioelectrical properties of rabbit acinar cell monolayers on polyester membrane scaffolds.

  American journal of physiology. Cell physiology 20071001

• Lessons in the diagnosis and management of Conn's syndrome.

  Clinical medicine (London, England) 20071001

• Conn's syndrome in pregnancy successfully treated with amiloride.

  Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20071001

• (NDRG2) stimulates amiloride-sensitive Na+ currents in Xenopus laevis oocytes and fisher rat thyroid cells.

  The Journal of biological chemistry 20070921

• Acid-induced modulation of airway basal tone and contractility: role of acid-sensing ion channels (ASICs) and TRPV1 receptor.

  Life sciences 20070908

• Distal colonic Na(+) absorption inhibited by luminal P2Y(2) receptors.

  Pflugers Archiv : European journal of physiology 20070901

• The rise of [Na(+)] (i) during ischemia and reperfusion in the rat heart-underlying mechanisms.

  Pflugers Archiv : European journal of physiology 20070901

• Bicarbonate-dependent pH(i) regulation by chondrocytes within the superficial zone of bovine articular cartilage.

  Journal of cellular physiology 20070901

• Intracellular sorting of galectin-8 based on carbohydrate fine specificity.

  Glycobiology 20070901

• Amiloride-sensitive Na+ channels contribute to regulatory volume increases in human glioma cells.

  American journal of physiology. Cell physiology 20070901

• [Effect of Na(+)/Ca(2+) exchange blocker, Benzamil, on alveolar macrophage function in patients with chronic obstructive pulmonary disease].

  Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20070901

• Lysophosphatidylserine increases membrane potentials in rat C6 glioma cells.

  Archives of pharmacal research 20070901

• Force-response considerations in ciliary mechanosensation.

  Biophysical journal 20070815

• Olfactory epithelia exhibit progressive functional and morphological defects in CF mice.

  American journal of physiology. Cell physiology 20070801

• Acute acidification or amiloride treatment suppresses the ability of Hsp70 to inhibit heat-induced apoptosis.

  Apoptosis : an international journal on programmed cell death 20070801

• Spontaneous autocrine release of protons activates ASIC-mediated currents in HEK293 cells.

  Journal of cellular physiology 20070801

• Hyperammonemia acts synergistically with lipopolysaccharide in inducing changes in cerebral hemodynamics in rats anaesthetised with pentobarbital.

  Journal of hepatology 20070801

• Pharmacological activators of AMP-activated protein kinase have different effects on Na+ transport processes across human lung epithelial cells.

  British journal of pharmacology 20070801

• Amiloride-insensitive units of the chorda tympani nerve are necessary for normal ammonium chloride detectability in the rat.

  Behavioral neuroscience 20070801

• Fast quantitative determination of diuretic drugs in tablets and human urine by microchip electrophoresis with native fluorescence detection.

  Electrophoresis 20070801

• The spironolactone, amiloride, losartan, and thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio.

  Circulation 20070717

• beta-Liddle mutation of the epithelial sodium channel increases alveolar fluid clearance and reduces the severity of hydrostatic pulmonary oedema in mice.

  The Journal of physiology 20070715

• NHE1 inhibition by amiloride- and benzoylguanidine-type compounds. Inhibitor binding loci deduced from chimeras of NHE1 homologues with endogenous differences in inhibitor sensitivity.

  The Journal of biological chemistry 20070706

• Endothelin-1 decreases [Ca2+]i via Na+/Ca2+ exchanger in CHO cells stably expressing endothelin ETA receptor.

  European journal of pharmacology 20070702

• Trafficking of ENaC subunits in response to acute insulin in mouse kidney.

  American journal of physiology. Renal physiology 20070701

• Loss of calcineurin homologous protein-1 in chicken B lymphoma DT40 cells destabilizes Na+/H+ exchanger isoform-1 protein.

  American journal of physiology. Cell physiology 20070701

• Vitamin B1 (thiamine) uptake by human retinal pigment epithelial (ARPE-19) cells: mechanism and regulation.

  The Journal of physiology 20070701

• Frog atrial natriuretic peptide and cGMP activate amiloride-sensitive Na(+) channels in urinary bladder cells of Japanese tree frog, Hyla japonica.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20070701

• Blockade of acid sensing ion channels attenuates the exercise pressor reflex in cats.

  The Journal of physiology 20070615

• Integrated microsystem for non-invasive electrophysiological measurements on Xenopus oocytes.

  Biosensors & bioelectronics 20070615

• pH-dependent toxicity of sulphur mustard in vitro.

  Toxicology and applied pharmacology 20070615

• Hypertonic shrinking but not hypotonic swelling increases sodium concentration in rat brain synaptosomes.

  Brain research bulletin 20070615

• Marine biology. Florida red tide brews up drug lead for cystic fibrosis.

  Science (New York, N.Y.) 20070615

• Amiloride inhibition of vacuolar Na+/H+ antiporter enhance salt stress in Zea mays L. seedlings.

  Pakistan journal of biological sciences : PJBS 20070615

• HSP60 trafficking in adult cardiac myocytes: role of the exosomal pathway.

  American journal of physiology. Heart and circulatory physiology 20070601

• Amiloride-sensitive sodium absorption is different in vertebrates and invertebrates.

  American journal of physiology. Regulatory, integrative and comparative physiology 20070601

• Basolateral P2X4-like receptors regulate the extracellular ATP-stimulated epithelial Na+ channel activity in renal epithelia.

  American journal of physiology. Renal physiology 20070601

• Crosstalk between the connecting tubule and the afferent arteriole regulates renal microcirculation.

  Kidney international 20070601

• Amiloride-insensitive nasal potential difference varies with the menstrual cycle in cystic fibrosis.

  Pediatric pulmonology 20070601

• A new cross-talk pathway between the renal tubule and its own glomerulus.

  Kidney international 20070601

• Extractive liquid-liquid spectrophotometric procedure for the determination of thiocyanate ions employing the ion pair reagent amiloride monohydrochloride.

  Analytica chimica acta 20070529

• Studies on the mechanisms underlying amiloride enhancement of 3,4-methylenedioxymethamphetamine-induced serotonin depletion in rats.

  European journal of pharmacology 20070521

• Extracellular proton modulates GABAergic synaptic transmission in rat hippocampal CA3 neurons.

  Brain research 20070511

• Delay of acute intracellular pH recovery after acidosis decreases endothelial cell activation.

  Journal of cellular physiology 20070501

• The role played by endocytosis in albumin-induced secretion of TGF-beta1 by proximal tubular epithelial cells.

  American journal of physiology. Renal physiology 20070501

• A psychophysical and electrophysiological analysis of salt taste in Trpv1 null mice.

  American journal of physiology. Regulatory, integrative and comparative physiology 20070501

• Mouse colon sensory neurons detect extracellular acidosis via TRPV1.

  American journal of physiology. Cell physiology 20070501

• Glucocorticoids stimulate ENaC upregulation in bovine mammary epithelium.

  American journal of physiology. Cell physiology 20070501

• Mechanisms of dietary Cu uptake in freshwater rainbow trout: evidence for Na-assisted Cu transport and a specific metal carrier in the intestine.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20070501

• NHE8 mediates amiloride-sensitive Na+/H+ exchange across mosquito Malpighian tubules and catalyzes Na+ and K+ transport in reconstituted proteoliposomes.

  American journal of physiology. Renal physiology 20070501

• Hypertonic saline inhibits luminal sodium channels in respiratory epithelium.

  European journal of applied physiology 20070501

• The non-genomic effects on Na+/H+-exchange 1 by progesterone and 20alpha-hydroxyprogesterone in human T cells.

  Journal of cellular physiology 20070501

• PGE2 reduces net water and chloride absorption from the rat colon by targeting the Na+/H+ exchanger and the Na+ K+ 2Cl- cotransporter.

  Prostaglandins, leukotrienes, and essential fatty acids 20070501

• Effect of diuretic therapy on exercise capacity in patients with chronic angina and preserved left ventricular function.

  Journal of cardiovascular pharmacology 20070501

• [Effect of amiloride on the pathology of a rat model of chronic obstructive pulmonary disease].

  Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20070501

• Recruitment of apical dendritic T-type Ca2+ channels by backpropagating spikes underlies de novo intrinsic bursting in hippocampal epileptogenesis.

  The Journal of physiology 20070415

• Involvement of forebrain in parabrachial neuronal activation induced by aversively conditioned taste stimuli in the rat.

  Brain research 20070413

• Reduction of intracellular pH inhibits the expression of VEGF in K562 cells after targeted inhibition of the Na+/H+ exchanger.

  Leukemia research 20070401

• Epithelial ion transport of human nasal polyp and paranasal sinus mucosa.

  American journal of respiratory cell and molecular biology 20070401

• Na channel expression and activity in the medullary collecting duct of rat kidney.

  American journal of physiology. Renal physiology 20070401

• Inhibition of lipopolysaccharide-induced prostaglandin E2 production and inflammation by the Na+/H+ exchanger inhibitors.

  The Journal of pharmacology and experimental therapeutics 20070401

• Isolation and characterization of an amiloride-resistant mutant of Methanothermobacter thermautotrophicus possessing a defective Na+/H+ antiport.

  FEMS microbiology letters 20070401

• An improved in vitro model of human intestinal follicle-associated epithelium to study nanoparticle transport by M cells.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070401

• A vacuolar-type H+-ATPase and a Na+/H+ exchanger contribute to intracellular pH regulation in cockroach salivary ducts.

  The Journal of experimental biology 20070401

• Sodium-hydrogen exchanger, cardiac overload, and myocardial hypertrophy.

  Circulation 20070306

• Angiotensin II increases chloride absorption in the cortical collecting duct in mice through a pendrin-dependent mechanism.

  American journal of physiology. Renal physiology 20070301

• Mechanisms of secretion-associated shrinkage and volume recovery in cultured rabbit parietal cells.

  American journal of physiology. Gastrointestinal and liver physiology 20070301

• Regulated ion transport in mouse liver cyst epithelial cells.

  Biochimica et biophysica acta 20070301

• Vitamin C transport and SVCT1 transporter expression in chick renal proximal tubule cells in culture.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20070301

• Identification of new small molecule inhibitors of cystic fibrosis transmembrane conductance regulator protein: in vitro and in vivo studies.

  Biological & pharmaceutical bulletin 20070301

• Amiloride-sensitive ion channels in urinary bladder epithelium involved in mechanosensory transduction by modulating stretch-evoked adenosine triphosphate release.

  Urology 20070301

• Role of Na+/H+ exchanger in the pathogenesis of ischemic acute renal failure in mice.

  Journal of cardiovascular pharmacology 20070301

• Improved stochastic resonance algorithm for enhancement of signal-to-noise ratio of high-performance liquid chromatographic signal.

  Analytica chimica acta 20070227

• Comparative efficacy of liposome-entrapped amiloride and free amiloride in animal models of seizures and serum potassium in mice.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20070201

• CFTR inhibition mimics the cystic fibrosis inflammatory profile.

  American journal of physiology. Lung cellular and molecular physiology 20070201

• TRPV4 as a flow sensor in flow-dependent K+ secretion from the cortical collecting duct.

  American journal of physiology. Renal physiology 20070201

• Interactions between Na+ channels and Na+-HCO3- cotransporters in the freshwater fish gill MR cell: a model for transepithelial Na+ uptake.

  American journal of physiology. Cell physiology 20070201

• Colony-stimulating factor-1 increases osteoclast intracellular pH and promotes survival via the electroneutral Na/HCO3 cotransporter NBCn1.

  Endocrinology 20070201

• Block by amiloride derivatives of odor-evoked discharge in lobster olfactory receptor neurons through action on a presumptive TRP channel.

  Chemical senses 20070201

• Altered ion transport and responsiveness to methacholine and hyperosmolarity in air interface-cultured guinea-pig tracheal epithelium.

  Journal of pharmacological and toxicological methods 20070101

• Characterisation of chloride currents across the proximal colon in CftrTgH(neoim)1Hgu congenic mice.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20070101

• Apical electrolyte concentration modulates barrier function and tight junction protein localization in bovine mammary epithelium.

  American journal of physiology. Cell physiology 20070101

• Sodium arsenite affects Na+ transport in the isolated skin of the toad Pleurodema thaul.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20070101

• Epithelial sodium channel inhibition in cardiovascular disease. A potential role for amiloride.

  American journal of hypertension 20070101

• Distinct domain-dependent effect of syntaxin1A on amiloride-sensitive sodium channel (ENaC) currents in HT-29 colonic epithelial cells.

  International journal of biological sciences 20070101

• Mechanisms of cardiodepression by an Na+-H+ exchange inhibitor methyl-N-isobutyl amiloride (MIA) on the heart: lack of beneficial effects in ischemia-reperfusion injury.

  Canadian journal of physiology and pharmacology 20070101

• Amiloride-sensitive sodium channels on the parietal human peritoneum: evidence by ussing-type chamber experiments.

  ASAIO journal (American Society for Artificial Internal Organs : 1992) 20070101

• Molecular mechanisms of sperm capacitation: progesterone-induced secondary calcium oscillations reflect the attainment of a capacitated state.

  Society of Reproduction and Fertility supplement 20070101

• [Hypotonic swelling activates the Na*/H* exchange in rat brain synaptosomes].

  Biofizika 20070101

• Simultaneous determination of amiloride and hydrochlorothiazide in human plasma by liquid chromatography/tandem mass spectrometry with positive/negative ion-switching electrospray ionisation.

  Rapid communications in mass spectrometry : RCM 20070101

• [Kinetic properties of sodium transport pathways in the river lamprey Lampetra fluviatilis erythrocytes].

  Zhurnal evoliutsionnoi biokhimii i fiziologii 20070101

• [Electrophysiological characteristics of ion transport in isolated rabbit trachea wall after in effect of mechanical stimuli and sodium transport inhibition].

  Annales Academiae Medicae Stetinensis 20070101

• Cl- channels of the distal nephron.

  American journal of physiology. Renal physiology 20061201

• ENaC proteins contribute to VSMC migration.

  American journal of physiology. Heart and circulatory physiology 20061201

• Modification of intracellular calcium concentration in cardiomyocytes by inhibition of sarcolemmal Na+/H+ exchanger.

  American journal of physiology. Heart and circulatory physiology 20061201

• Amiloride attenuates glycine-induced currents in cultured neurons of rat inferior colliculus.

  Biochemical and biophysical research communications 20061201

• Positive inotropic effects of carbon monoxide-releasing molecules (CO-RMs) in the isolated perfused rat heart.

  British journal of pharmacology 20061201

• Drug-protein interaction with Vpu from HIV-1: proposing binding sites for amiloride and one of its derivatives.

  Analytical and bioanalytical chemistry 20061201

• Effects of Na+/H+ exchanger inhibitors on subcellular localisation of endocytic organelles and intracellular dynamics of protein transduction domains HIV-TAT peptide and octaarginine.

  Journal of controlled release : official journal of the Controlled Release Society 20061128

• The internalization and degradation of human copper transporter 1 following cisplatin exposure.

  Cancer research 20061115

• Mineralisation of 2,6-dichlorobenzamide (BAM) in dichlobenil-exposed soils and isolation of a BAM-mineralising Aminobacter sp.

  Environmental pollution (Barking, Essex : 1987) 20061101

• Alveolar fluid reabsorption is increased in rats with compensated heart failure.

  American journal of physiology. Lung cellular and molecular physiology 20061101

• Impaired intestinal NHE3 activity in the PDK1 hypomorphic mouse.

  American journal of physiology. Gastrointestinal and liver physiology 20061101

• Transporters involved in regulation of intracellular pH in primary cultured rat brain endothelial cells.

  The Journal of physiology 20061101

• Detection of NaCl and KCl in TRPV1 knockout mice.

  Chemical senses 20061101

• The connecting tubule is the main site of the furosemide-induced urinary acidification by the vacuolar H+-ATPase.

  Kidney international 20061101

• Amiloride-sensitive nasal potential difference is not changed by estradiol and progesterone replacement but relates to BPD or death in a randomized trial on preterm infants.

  Pediatric research 20061101

• Antiangiogenic effects of spironolactone and other potassium-sparing diuretics in human umbilical vein endothelial cells and in fibrin gel chambers implanted in rats.

  Journal of hypertension 20061101

• Central receptors mediating the cardiovascular actions of melanocyte stimulating hormones.

  Journal of hypertension 20061101

• Amiloride moderates increased gut permeability and diminishes mesenteric lymph-mediated priming of neutrophils in trauma/hemorrhagic shock.

  Surgery 20061101

• A novel spliced variant of the epithelial Na+ channel delta-subunit in the human brain.

  Biochemical and biophysical research communications 20061013

• Dopamine activates amiloride-sensitive sodium channels in alveolar type I cells in lung slice preparations.

  American journal of physiology. Lung cellular and molecular physiology 20061001

• NHE2 is the main apical NHE in mouse colonic crypts but an alternative Na+-dependent acid extrusion mechanism is upregulated in NHE2-null mice.

  American journal of physiology. Gastrointestinal and liver physiology 20061001

• Mutations in the cystic fibrosis transmembrane regulator gene and in vivo transepithelial potentials.

  American journal of respiratory and critical care medicine 20061001

• Relative contribution of V-H+ATPase and NA+/H+ exchanger to bicarbonate reabsorption in proximal convoluted tubules of old rats.

  Aging cell 20061001

• Active ammonia absorption in the midgut of the Tobacco hornworm Manduca sexta L.: transport studies and mRNA expression analysis of a Rhesus-like ammonia transporter.

  Insect biochemistry and molecular biology 20061001

• Hexamethylene amiloride blocks E protein ion channels and inhibits coronavirus replication.

  Virology 20060930

• Airway surface liquid volume regulates ENaC by altering the serine protease-protease inhibitor balance: a mechanism for sodium hyperabsorption in cystic fibrosis.

  The Journal of biological chemistry 20060922

• The antiepileptic drug carbamazepine affects sodium transport in toad epithelium.

  Toxicology in vitro : an international journal published in association with BIBRA 20060901

• Phe-met-arg-phe (FMRF)-amide is a substrate source of NO synthase in the gastropod nervous system.

  Cell and tissue research 20060901

• Mechanism underlying flow stimulation of sodium absorption in the mammalian collecting duct.

  American journal of physiology. Renal physiology 20060901

• Hypertonic saline therapy in cystic fibrosis: Evidence against the proposed mechanism involving aquaporins.

  The Journal of biological chemistry 20060901

• Sustained currents through ASIC3 ion channels at the modest pH changes that occur during myocardial ischemia.

  Circulation research 20060901

• Activation of sodium transport in rat erythrocytes by inhibition of protein phosphatases 1 and 2A.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20060901

• Molecular characterization of sodium/proton exchanger 3 (NHE3) from the yellow fever vector, Aedes aegypti.

  The Journal of experimental biology 20060901

• Segmental heterogeneity of epithelial ion transport induced by stimulants in rat distal colon.

  Biological & pharmaceutical bulletin 20060901

• Semiautonomous development of the extraembryonic membranes in the chicken embryo.

  Poultry science 20060901

• Measurement of the filtration coefficient (Kfc) in the lung of Gallus domesticus and the effects of increased microvascular permeability.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20060801

• Sex differences in the effects of amiloride on formalin test nociception in mice.

  American journal of physiology. Regulatory, integrative and comparative physiology 20060801

• Metabolic regulation of neutrophil spreading, membrane tubulovesicular extensions (cytonemes) formation and intracellular pH upon adhesion to fibronectin.

  Experimental cell research 20060801

• A novel type of cold-sensitive neuron in rat dorsal root ganglia with rapid adaptation to cooling stimuli.

  The European journal of neuroscience 20060801

• Effect of terbutaline on alveolar liquid clearance after oleic acid-induced lung injury in rats.

  Chinese journal of traumatology = Zhonghua chuang shang za zhi 20060801

• Intrasperm Ca2+ modulation and human ejaculated sperm viability: influence of miconazole, clotrimazole and loperamide.

  The Journal of pharmacy and pharmacology 20060801

• Cytotoxic mechanisms of Zn2+ and Cd2+ involve Na+/H+ exchanger (NHE) activation by ROS.

  Aquatic toxicology (Amsterdam, Netherlands) 20060720

• Surface expression of ASIC2 inhibits the amiloride-sensitive current and migration of glioma cells.

  The Journal of biological chemistry 20060714

• Characterization of acid signaling in rat vagal pulmonary sensory neurons.

  American journal of physiology. Lung cellular and molecular physiology 20060701

• Prenatal estrogen and progesterone deprivation impairs alveolar formation and fluid clearance in newborn piglets.

  Pediatric research 20060701

• Amiloride inhibition on NaCl responses of the chorda tympani nerve in two 129 substrains of mice, 129P3/J and 129X1/SvJ.

  Chemical senses 20060701

• Carbonic anhydrases and mucosal vanilloid receptors help mediate the hyperemic response to luminal CO2 in rat duodenum.

  Gastroenterology 20060701

• Potassium-sparing diuretics.

  Nursing times 20060701

• Epithelial carbonic anhydrases facilitate PCO2 and pH regulation in rat duodenal mucosa.

  The Journal of physiology 20060615

• Chronic high glucose inhibits albumin reabsorption by lysosomal alkalinization in cultured porcine proximal tubular epithelial cells (LLC-PK1).

  Diabetes research and clinical practice 20060601

• Characterization of regulatory mechanisms and states of human organic cation transporter 2.

  American journal of physiology. Cell physiology 20060601

• Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel.

  The Journal of clinical investigation 20060601

• Lithium poisoning: pharmacokinetics and clearance during different therapeutic measures.

  Journal of clinical psychopharmacology 20060601

• Effects of bafilomycin A1, a vacuolar type H+ ATPase inhibitor, on the thermosensitivity of a human pancreatic cancer cell line.

  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 20060601

• The effects of thiazide and thiazide-potassium sparing diuretics on fibrinolytic system parameters.

  Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20060601

• [Effect of the NHE-1-specific inhibitor DMA on pHi, proliferation and apoptosis of HL-60/ADM cells in vitro].

  Zhongguo shi yan xue ye xue za zhi 20060601

• Epithelial sodium channel is regulated by SNAP-23/syntaxin 1A interplay.

  Biochemical and biophysical research communications 20060519

• Hormonal regulation of the epithelial Na+ channel: from amphibians to mammals.

  General and comparative endocrinology 20060515

• Involvement of Na+/H+ exchanger in the calcium signaling in epimastigotes of Trypanosoma cruzi.

  FEBS letters 20060515

• The role of the capsaicin receptor TRPV1 and acid-sensing ion channels (ASICS) in proton sensitivity of subpopulations of primary nociceptive neurons in rats and mice.

  Neuroscience 20060512

• Methotrexate induces cell swelling and necrosis in renal tubular cells.

  Pediatric blood & cancer 20060501

• Control of intracellular trafficking of ICAM-1-targeted nanocarriers by endothelial Na+/H+ exchanger proteins.

  American journal of physiology. Lung cellular and molecular physiology 20060501

• Larval bullfrog skin expresses ENaC despite having no amiloride-blockable transepithelial Na+ transport.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20060501

• Nucleotide regulation of paracellular Cl- permeability in natural rabbit airway epithelium.

  Pflugers Archiv : European journal of physiology 20060501

• Sucrose and monosodium glutamate taste thresholds and discrimination ability of T1R3 knockout mice.

  Chemical senses 20060501

• A novel mechanosensitive channel identified in sensory neurons.

  The European journal of neuroscience 20060501

• Hypertonic saline for cystic fibrosis.

  The New England journal of medicine 20060427

• The effect of acidosis on adenosine release from cultured rat forebrain neurons.

  Brain research 20060412

• Heightened epithelial Na+ channel-mediated Na+ absorption in a murine polycystic kidney disease model epithelium lacking apical monocilia.

  American journal of physiology. Cell physiology 20060401

• RNA interference for alpha-ENaC inhibits rat lung fluid absorption in vivo.

  American journal of physiology. Lung cellular and molecular physiology 20060401

• Protective effect of endogenous beta-adrenergic tone on lung fluid balance in acute bacterial pneumonia in mice.

  American journal of physiology. Lung cellular and molecular physiology 20060401

• The pharmacological treatment of primary aldosteronism.

  Expert opinion on pharmacotherapy 20060401

• [Sodium transport and its regulation of acutely isolated alveolar type II cells].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20060401

• Delta-subunit confers novel biophysical features to alpha beta gamma-human epithelial sodium channel (ENaC) via a physical interaction.

  The Journal of biological chemistry 20060324

• Strong and selective binding of amiloride to thymine base opposite AP sites in DNA duplexes: simultaneous binding to DNA phosphate backbone.

  Chemical communications (Cambridge, England) 20060321

• Hyposecretion, not hyperabsorption, is the basic defect of cystic fibrosis airway glands.

  The Journal of biological chemistry 20060317

• The carboxyl terminus of the alpha-subunit of the amiloride-sensitive epithelial sodium channel binds to F-actin.

  The Journal of biological chemistry 20060310

• Sodium and epithelial sodium channels participate in the regulation of the capacitation-associated hyperpolarization in mouse sperm.

  The Journal of biological chemistry 20060303

• Congenital diaphragmatic hernia prevents absorption of distal air space fluid in late-gestation rat fetuses.

  American journal of physiology. Lung cellular and molecular physiology 20060301

• Flagellin of Pseudomonas aeruginosa inhibits Na+ transport in airway epithelia.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301

• 17beta-estradiol increases volume, apical surface and elasticity of human endothelium mediated by Na+/H+ exchange.

  Cardiovascular research 20060301

• Angiotensin II acutely decreases myocardial stiffness: a novel AT1, PKC and Na+/H+ exchanger-mediated effect.

  British journal of pharmacology 20060301

• Epithelial sodium channel allele T594M is not associated with blood pressure or blood pressure response to amiloride.

  Hypertension (Dallas, Tex. : 1979) 20060301

• Topical amiloride ointment accelerates healing of mechanical skin ulcers in albino rabbits and patients.

  Methods and findings in experimental and clinical pharmacology 20060301

• Forskolin-induced cell shrinkage and apical translocation of functional enhanced green fluorescent protein-human alphaENaC in H441 lung epithelial cell monolayers.

  The Journal of biological chemistry 20060224

• Rab4 GTP/GDP modulates amiloride-sensitive sodium channel (ENaC) function in colonic epithelia.

  Biochemical and biophysical research communications 20060210

• Calcium-permeable acid-sensing ion channel is a molecular target of the neurotoxic metal ion lead.

  The Journal of biological chemistry 20060203

• Molecular cloning and functional characterization of the Aplysia FMRFamide-gated Na+ channel.

  Pflugers Archiv : European journal of physiology 20060201

• Axial flow modulates proximal tubule NHE3 and H-ATPase activities by changing microvillus bending moments.

  American journal of physiology. Renal physiology 20060201

• ENaC proteins are required for NGF-induced neurite growth.

  American journal of physiology. Cell physiology 20060201

• Vanilloid type 1 receptor and the acid-sensing ion channel mediate acid phosphate activation of muscle afferent nerves in rats.

  Journal of applied physiology (Bethesda, Md. : 1985) 20060201

• Amplification of the urokinase gene and the sensitivity of prostate cancer cells to urokinase inhibitors.

  BJU international 20060201

• N-methyl-isobutyl-amiloride ameliorates brain injury when commenced before hypoxia ischemia in neonatal mice.

  Pediatric research 20060201

• Involvement of the Na+/H+ exchanger in membrane phosphatidylserine exposure during human platelet activation.

  Biochimica et biophysica acta 20060201

• [Liddle syndrome: Pathogenesis, pathophysiology, and therapy].

  Nihon rinsho. Japanese journal of clinical medicine 20060201

• Influence of fasting on the effects of dimethylamiloride and oxfenicine on ischaemic-reperfused rat hearts.

  Archives of physiology and biochemistry 20060201

• Enhanced central hypertonic saline-induced activation of angiotensin II-sensitive neurons in the anterior hypothalamic area of spontaneously hypertensive and Dahl S rats.

  Brain research bulletin 20060130

• Mucus clearance and lung function in cystic fibrosis with hypertonic saline.

  The New England journal of medicine 20060119

• Glucocorticoid regulation of genes in the amiloride-sensitive sodium transport pathway by semicircular canal duct epithelium of neonatal rat.

  Physiological genomics 20060112

• Involvement of Na+/Ca2+ exchanger in catecholamine-induced increase in intracellular calcium in cardiomyocytes.

  American journal of physiology. Heart and circulatory physiology 20060101

• ENaC- and CFTR-dependent ion and fluid transport in human middle ear epithelial cells.

  Hearing research 20060101

• Potential difference measurements of ocular surface Na+ absorption analyzed using an electrokinetic model.

  Investigative ophthalmology & visual science 20060101

• Membrane transduction of oligoarginine in HeLa cells is not mediated by macropinocytosis.

  Molecular pharmaceutics 20060101

• Electrogenic ammonium transport by renal Rhbg.

  Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine 20060101

• A rapid nongenomic effect of aldosterone on intracellular sodium concentration in the distal nephron segment of the rat.

  Doklady. Biochemistry and biophysics 20060101

• Anticonvulsant effect of amiloride in pentetrazole-induced status epilepticus in mice.

  Pharmacological reports : PR 20060101

• Inhibition of macropinocytosis blocks antigen presentation of type II collagen in vitro and in vivo in HLA-DR1 transgenic mice.

  Arthritis research & therapy 20060101

• Expression of AmphiNaC, a new member of the amiloride-sensitive sodium channel related to degenerins and epithelial sodium channels in amphioxus.

  International journal of biological sciences 20060101

• Hypertonicity-induced cation channels.

  Acta physiologica (Oxford, England) 20060101

• Cystic fibrosis in 65- and 67-year-old siblings. Clinical feature and nasal potential difference measurement in patients with genotypes F508del and 2789+5G-->A.

  Respiration; international review of thoracic diseases 20060101

• The renal epithelial sodium channel: genetic heterogeneity and implications for the treatment of high blood pressure.

  Current pharmaceutical design 20060101

• PGE2-induced apoptotic cell death in K562 human leukaemia cells.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20060101

• Amiloride resistance in the methanoarcheon Methanothermobacter thermoautotrophicus: characterization of membrane-associated proteins.

  Folia microbiologica 20060101

• The CF-CIRC study: a French collaborative study to assess the accuracy of cystic fibrosis diagnosis in neonatal screening.

  BMC pediatrics 20060101

• Validation of coronavirus E proteins ion channels as targets for antiviral drugs.

  Advances in experimental medicine and biology 20060101

• Nano-liposomal dry powder inhaler of Amiloride Hydrochloride.

  Journal of nanoscience and nanotechnology 20060101

• Cell volume-regulated cation channels.

  Contributions to nephrology 20060101

• [Structural and functional organization of Na+ transport in epithelial systems. I. Epithelial Na+ channels].

  Tsitologiia 20060101

• Vectorial bicarbonate transport by Capan-1 cells: a model for human pancreatic ductal secretion.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20060101

• Differential contribution of troponin I phosphorylation sites to the endothelin-modulated contractile response.

  The Journal of biological chemistry 20051216

• Phosphatidylinositol 3,4,5-trisphosphate mediates aldosterone stimulation of epithelial sodium channel (ENaC) and interacts with gamma-ENaC.

  The Journal of biological chemistry 20051209

• Rab proteins regulate epithelial sodium channel activity in colonic epithelial HT-29 cells.

  Biochemical and biophysical research communications 20051202

• Oxytocin-induced labor augments IL-1beta-stimulated lung fluid absorption in fetal guinea pig lungs.

  American journal of physiology. Lung cellular and molecular physiology 20051201

• Efficacy of COX-2 inhibitors in a case of congenital nephrogenic diabetes insipidus.

  Pediatric nephrology (Berlin, Germany) 20051201

• In vivo demonstration of the absorptive function of the middle ear epithelium.

  Hearing research 20051201

• Effects of cadmium on Na+ transport in the isolated skin of the toad Pleurodema thaul.

  Journal of inorganic biochemistry 20051201

• Mechanisms for nongenomic and genomic effects of aldosterone on Na+/H+ exchange in vascular smooth muscle cells.

  Journal of hypertension 20051201

• Characteristics of GABA release in mouse brain stem slices under normal and ischemic conditions.

  Neurochemical research 20051201

• Crystallization and preliminary X-ray diffraction studies of the WW4 domain of the Nedd4-2 ubiquitin-protein ligase.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20051201

• Progesterone down-regulates the open probability of the amiloride-sensitive epithelial sodium channel via a Nedd4-2-dependent mechanism.

  The Journal of biological chemistry 20051118

• Inhibitory effect of amiloride and gadolinium on fine afferent nerves in the rat knee: evidence of mechanogated ion channels in joints.

  Experimental brain research 20051101

• Central role for ENaC in development of hypertension.

  Journal of the American Society of Nephrology : JASN 20051101

• Cell volume regulation during hyperosmotic shrinkage is mediated by Na+/K+-ATPase and Na+-K+-2Cl- cotransporter in Necturus gastrics surface epithelial cells.

  Digestive diseases and sciences 20051101

• Protein transduction of dendritic cells for NY-ESO-1-based immunotherapy of myeloma.

  Cancer research 20051101

• The blood-brain barrier transmigrating single domain antibody: mechanisms of transport and antigenic epitopes in human brain endothelial cells.

  Journal of neurochemistry 20051101

• Amiloride combined with small-volume resuscitation with hypertonic saline is superior in ameliorating trauma-hemorrhagic shock-induced lung injury in rats to the administration of either agent alone.

  Critical care medicine 20051101

• Modulation of Na+ transport and epithelial sodium channel expression by protein kinase C in rat alveolar epithelial cells.

  Canadian journal of physiology and pharmacology 20051101

• [Na+-H+ exchanger protein changes in vascular smooth muscle and effect of Na+-H+ exchange inhibitor on vessel stenosis after balloon injuries in rabbits].

  Zhonghua xin xue guan bing za zhi 20051101

• Characterization of the redox components of transplasma membrane electron transport system from Leishmania donovani promastigotes.

  Biochimica et biophysica acta 20051010

• Vascular ENaC proteins are required for renal myogenic constriction.

  American journal of physiology. Renal physiology 20051001

• Opposite effects of Ni2+ on Xenopus and rat ENaCs expressed in Xenopus oocytes.

  American journal of physiology. Cell physiology 20051001

• Icilin activates the delta-subunit of the human epithelial Na+ channel.

  Molecular pharmacology 20051001

• Role of HER-2/neu signaling in sensitivity to tumor necrosis factor-related apoptosis-inducing ligand: enhancement of TRAIL-mediated apoptosis by amiloride.

  Journal of cellular biochemistry 20051001

• Properties of motility in Bacillus subtilis powered by the H+-coupled MotAB flagellar stator, Na+-coupled MotPS or hybrid stators MotAS or MotPB.

  Journal of molecular biology 20050916

• Positive benefits of a pharmacist-managed hypertension clinic in Nigeria.

  Public health 20050901

• Regulatory interdependence of cloned epithelial Na+ channels and P2X receptors.

  Journal of the American Society of Nephrology : JASN 20050901

• Electrophysiological and in vivo characterization of A-317567, a novel blocker of acid sensing ion channels.

  Pain 20050901

• Wound-induced migration of MDA-MB-435 and SKOV-3 cancer cells is regulated by plasminogen activator inhibitor-1.

  International journal of oncology 20050901

• Improvement in blood pressure with inhibition of the epithelial sodium channel in blacks with hypertension.

  Hypertension (Dallas, Tex. : 1979) 20050901

• Improvement of blood pressure with inhibition of the epithelial sodium channel in blacks with hypertension.

  Hypertension (Dallas, Tex. : 1979) 20050901

• Targeting of urokinase plasminogen activator receptor in human pancreatic carcinoma cells inhibits c-Met- and insulin-like growth factor-I receptor-mediated migration and invasion and orthotopic tumor growth in mice.

  Cancer research 20050901

• [Nephrogenic diabetes insipidus induced by colchicine--a case report].

  Polskie Archiwum Medycyny Wewnetrznej 20050901

• Characterization of a proton-activated, outwardly rectifying anion channel.

  The Journal of physiology 20050815

• Na+-inhibitory sites of the Na+/H+ exchanger are Li+ substrate sites.

  American journal of physiology. Cell physiology 20050801

• A biomimetic tissue from cultured normal human urothelial cells: analysis of physiological function.

  American journal of physiology. Renal physiology 20050801

• Amiloride protects against pentylenetetrazole-induced kindling in mice.

  British journal of pharmacology 20050801

• Resolution of medullary nephrocalcinosis in children with metabolic bone disorders.

  Pediatric nephrology (Berlin, Germany) 20050801

• Hypothermia and amiloride preserve energetics in a neonatal brain slice model.

  Pediatric research 20050801

• Thiazolidinediones expand body fluid volume through PPARgamma stimulation of ENaC-mediated renal salt absorption.

  Nature medicine 20050801

• Mechanisms behind Pb-induced disruption of Na+ and Cl- balance in rainbow trout (Oncorhynchus mykiss).

  American journal of physiology. Regulatory, integrative and comparative physiology 20050801

• Combination aerosol therapy to treat Burkholderia cepacia complex.

  The European respiratory journal 20050801

• Sources of activator calcium ions in the contraction of smooth muscles in Aplysia kurodai.

  Zoological science 20050801

• Na+/H+ exchanger activity is increased in doxorubicin-resistant human colon cancer cells and its modulation modifies the sensitivity of the cells to doxorubicin.

  International journal of cancer 20050720

• On the interaction between amiloride and its putative alpha-subunit epithelial Na+ channel binding site.

  The Journal of biological chemistry 20050715

• Synergic action of insulin and genistein on Na+/K+/2Cl- cotransporter in renal epithelium.

  Biochemical and biophysical research communications 20050715

• Regulation of ion transport via apical purinergic receptors in intact rabbit airway epithelium.

  Pflugers Archiv : European journal of physiology 20050701

• Evidence that membrane transduction of oligoarginine does not require vesicle formation.

  Experimental cell research 20050701

• Dual modes of 5-(N-ethyl-N-isopropyl)amiloride modulation of apical dipeptide uptake in the human small intestinal epithelial cell line Caco-2.

  Cellular and molecular life sciences : CMLS 20050701

• Expression of amiloride-sensitive epithelial sodium channels in mouse taste cells after chorda tympani nerve crush.

  Chemical senses 20050701

• Zinc and 17beta-estradiol induce modifications in Na+/H+ exchanger and pyruvate kinase activity through protein kinase C in isolated mantle/gonad cells of Mytilus galloprovincialis.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20050701

• Effect of amiloride and bumetanide on transepithelial ion transport in isolated rabbit cecal and colonic wall.

  Postepy higieny i medycyny doswiadczalnej (Online) 20050603

• Domain near TM1 influences agonist and antagonist responses of peptide-gated Na+ channels.

  Pflugers Archiv : European journal of physiology 20050601

• A possible role for membrane depolarization in epithelial wound healing.

  American journal of physiology. Cell physiology 20050601

• Determination of antihypertensive mixtures by use of a chemometrics-assisted spectrophotometric method.

  Analytical and bioanalytical chemistry 20050601

• Characterization of active ion transport across primary rabbit corneal epithelial cell layers (RCrECL) cultured at an air-interface.

  Experimental eye research 20050601

• In vitro effects of deoxynivalenol on electrical properties of intestinal mucosa of laying hens.

  Poultry science 20050601

• Allosteric modulation of dopamine receptors.

  Mini reviews in medicinal chemistry 20050601

• Epithelial sodium channel inhibition by AMP-activated protein kinase in oocytes and polarized renal epithelial cells.

  The Journal of biological chemistry 20050506

• Blockade of brain mineralocorticoid receptors or Na+ channels prevents sympathetic hyperactivity and improves cardiac function in rats post-MI.

  American journal of physiology. Heart and circulatory physiology 20050501

• A role for ERK1/2 in EGF- and ATP-dependent regulation of amiloride-sensitive sodium absorption.

  American journal of physiology. Cell physiology 20050501

• Evidence for simultaneous 1Na+:1Mg2+ and ping pong 2Na+:1Mg2+ exchangers in rat thymocyte.

  Frontiers in bioscience : a journal and virtual library 20050501

• Taste discrimination between NaCl and KCl is disrupted by amiloride in inbred mice with amiloride-insensitive chorda tympani nerves.

  American journal of physiology. Regulatory, integrative and comparative physiology 20050501

• Increased intracellular pH at the macula densa activates nNOS during tubuloglomerular feedback.

  Kidney international 20050501

• Direct measurement of acid efflux from isolated guinea pig pancreatic ducts.

  Pancreas 20050501

• Gitelman's syndrome presenting as intolerance to statin therapy.

  Annals of clinical biochemistry 20050501

• Amelioration of experimental colitis by Na-H exchanger-1 inhibitor amiloride is associated with reversal of IL-1ss and ERK mitogen-activated protein kinase.

  Scandinavian journal of gastroenterology 20050501

• Catalase activity and thiobarbituric acid reactive substances (TBARS) production in a rat model of diffuse axonal injury. Effect of gadolinium and amiloride.

  Neurochemical research 20050501

• Signaling pathways in the biphasic effect of ANG II on Na+/H+ exchanger in T84 cells.

  The Journal of membrane biology 20050501

• Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050420

• Proton-mediated feedback inhibition of presynaptic calcium channels at the cone photoreceptor synapse.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050420

• Effects of hyperosmolarity and airway epithelial ion transport inhibitors on sodium nitroprusside-induced relaxation of guinea pig trachea.

  Respiratory physiology & neurobiology 20050415

• Differential responses of bladder lumbosacral and thoracolumbar dorsal root ganglion neurons to purinergic agonists, protons, and capsaicin.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050413

• An IkappaB-beta COOH terminal region protein is essential for the proliferation of CHO cells under acidic stress.

  Journal of cellular physiology 20050401

• Muscarinic activation of Na+-dependent ion transporters and modulation by bicarbonate in rat submandibular gland acinus.

  American journal of physiology. Gastrointestinal and liver physiology 20050401

• Cultured monolayers of the dog jejunum with the structural and functional properties resembling the normal epithelium.

  American journal of physiology. Gastrointestinal and liver physiology 20050401

• The effect of varying tonicity on nasal epithelial ion transport in cystic fibrosis.

  American journal of respiratory and critical care medicine 20050401

• A novel epithelial sodium channel beta-subunit mutation associated with hypertensive Liddle syndrome.

  Pediatric nephrology (Berlin, Germany) 20050401

• CFTR-regulated chloride transport at the ocular surface in living mice measured by potential differences.

  Investigative ophthalmology & visual science 20050401

• The basolateral NHE1 Na+/H+ exchanger regulates transepithelial HCO3- absorption through actin cytoskeleton remodeling in renal thick ascending limb.

  The Journal of biological chemistry 20050325

• Dose-dependent inorganic mercury absorption by isolated perfused intestine of rainbow trout, Oncorhynchus mykiss, involves both amiloride-sensitive and energy-dependent pathways.

  Aquatic toxicology (Amsterdam, Netherlands) 20050325

• Influence of water chemistry and natural organic matter on active and passive uptake of inorganic mercury by gills of rainbow trout (Oncorhynchus mykiss).

  Aquatic toxicology (Amsterdam, Netherlands) 20050325

• Side chain orientation of residues lining the selectivity filter of epithelial Na+ channels.

  The Journal of biological chemistry 20050304

• Amiloride peptide conjugates: prodrugs for sodium-proton exchange inhibition.

  The Journal of pharmacology and experimental therapeutics 20050301

• Abnormal EGF-dependent regulation of sodium absorption in ARPKD collecting duct cells.

  American journal of physiology. Renal physiology 20050301

• Gene regulation of ENaC subunits by serum- and glucocorticoid-inducible kinase-1.

  American journal of physiology. Renal physiology 20050301

• Sodium/hydrogen exchange activity in sepsis and in sepsis complicated by previous injury: 31P and 23Na NMR study.

  Critical care medicine 20050301

• Physiological characterisation of a pH- and calcium-dependent sodium uptake mechanism in the freshwater crustacean, Daphnia magna.

  The Journal of experimental biology 20050301

• Heat-induced changes in intracellular Na+, pH and bioenergetic status in superfused RIF-1 tumour cells determined by 23Na and 31P magnetic resonance spectroscopy.

  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 20050301

• HPLC and chemometric-assisted spectrophotometric methods for simultaneous determination of atenolol, amiloride hydrochloride and chlorthalidone.

  Farmaco (Societa chimica italiana : 1989) 20050301

• External bioenergy-induced increases in intracellular free calcium concentrations are mediated by Na+/Ca2+ exchanger and L-type calcium channel.

  Molecular and cellular biochemistry 20050301

• Dengue virus M protein C-terminal peptide (DVM-C) forms ion channels.

  The Journal of membrane biology 20050301

• Benzamil, a blocker of epithelial Na(+) channel-induced upregulation of artery oxygen pressure level in acute lung injury rabbit ventilated with high frequency oscillation.

  Biochemical and biophysical research communications 20050218

• Mutations in the pore region modify epithelial sodium channel gating by shear stress.

  The Journal of biological chemistry 20050211

• Amiloride and the regulation of NF-kappaB: an unsung crosstalk and missing link between fluid dynamics and oxidative stress-related inflammation--controversy or pseudo-controversy?

  Biochemical and biophysical research communications 20050211

• GI262570, a peroxisome proliferator-activated receptor {gamma} agonist, changes electrolytes and water reabsorption from the distal nephron in rats.

  The Journal of pharmacology and experimental therapeutics 20050201

• Functional properties and pharmacological inhibition of ASIC channels in the human SJ-RH30 skeletal muscle cell line.

  The Journal of physiology 20050201

• Ca2+ current-driven nonlinear amplification by the mammalian cochlea in vitro.

  Nature neuroscience 20050201

• Amiloride uptake and toxicity in fission yeast are caused by the pyridoxine transporter encoded by bsu1+ (car1+).

  Eukaryotic cell 20050201

• Sclerochoroidal calcification in a patient with classic Bartter's syndrome.

  American journal of ophthalmology 20050201

• Impaired regulation of pH homeostasis by oxidative stress in rat brain capillary endothelial cells.

  Cellular and molecular neurobiology 20050201

• Amiloride potentiates TRAIL-induced tumor cell apoptosis by intracellular acidification-dependent Akt inactivation.

  Biochemical and biophysical research communications 20050128

• Different contributions of endothelin-A and endothelin-B receptors in postischemic cardiac dysfunction and norepinephrine overflow in rat hearts.

  Circulation 20050125

• 2-Aminoperimidine, a specific inhibitor of bacterial NhaA Na(+)/H(+) antiporters.

  FEBS letters 20050117

• Amiloride augments TRAIL-induced apoptotic death by inhibiting phosphorylation of kinases and phosphatases associated with the P13K-Akt pathway.

  Oncogene 20050113

• Amphotericin-B-mediated reactivation of latent HIV-1 infection.

  Virology 20050105

• Sodium channels are required during in vivo sodium chloride hyperosmolarity to stimulate increase in intestinal endothelial nitric oxide production.

  American journal of physiology. Heart and circulatory physiology 20050101

• The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signals.

  Nature neuroscience 20050101

• Effect of amiloride on gustatory responses in the ventroposteromedial nucleus of the thalamus in rats.

  Journal of neurophysiology 20050101

• Inhibition of prostasin expression by TGF-beta1 in renal epithelial cells.

  Kidney international 20050101

• Induction of 11beta-hydroxysteroid dehydrogenase type 2 and hyperaldosteronism are essential for enhanced sodium absorption after total colectomy in rats.

  Surgery 20050101

• Sodium-sensitive and -insensitive copper accumulation by isolated intestinal cells of rainbow trout Oncorhynchus mykiss.

  The Journal of experimental biology 20050101

• A novel vanilloid receptor-1 (VR-1) variant mammalian salt taste receptor.

  Chemical senses 20050101

• A pharmacological examination of Na+ and Cl- transport in two species of freshwater fish.

  Physiological and biochemical zoology : PBZ 20050101

• Catecholamine clearance from alveolar spaces of rat and human lungs.

  Respiration; international review of thoracic diseases 20050101

• A mathematical model of electrolyte and fluid transport across corneal endothelium.

  The Journal of membrane biology 20050101

• Effects of inhibition of urokinase-type plasminogen activator (u-PA) by amiloride in the cornea and tear fluid of eyes irradiated with UVB.

  Acta histochemica 20050101

• Transforming growth factor-beta is activated by plasmin and inhibits smooth muscle cell death in human saphenous vein.

  Journal of vascular research 20050101

• Cardiac myocyte accumulation of calcium in burn injury: cause or effect of myocardial contractile dysfunction.

  The Journal of burn care & rehabilitation 20050101

• Induction of contracture and extracellular Ca2+ influx in cardiac muscle by sanguinarine: a study on cardiotoxicity of sanguinarine.

  Journal of biomedical science 20050101

• Blockade of amiloride-sensitive sodium channels alters multiple components of the mammalian electroretinogram.

  Visual neuroscience 20050101

• Purinergic P2Y6 receptors induce Ca2+ and CFTR dependent Cl- secretion in mouse trachea.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20050101

• Effects of amiloride and bumetanide on hyperpolarization after movement across the distal colon epithelium.

  Pharmacological reports : PR 20050101

• Effects of halothane and isoflurane on stimulated airway transepithelial ion transport.

  Pharmacological reports : PR 20050101

• Influence of the sodium transport inhibition by amiloride on the transmesothelial resistance of isolated visceral sheep peritoneum.

  Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20050101

• [Regulation by vasopressin of NaCl absorption in the renal collecting duct].

  Journal de la Societe de biologie 20050101

• CO2 transduction mechanisms in avian intrapulmonary chemoreceptors: experiments and models.

  Respiratory physiology & neurobiology 20041215

• Membrane cholesterol content modulates activation of BK channels in colonic epithelia.

  Biochimica et biophysica acta 20041215

• Channel activity of a viral transmembrane peptide in micro-BLMs: Vpu(1-32) from HIV-1.

  Journal of the American Chemical Society 20041215

• Novel antiinflammatory vascular benefits of systemic and stent-based delivery of ethylisopropylamiloride.

  Circulation 20041214

• [Lethal polypharmacy in a patient with arterial hypertension].

  Deutsche medizinische Wochenschrift (1946) 20041210

• Evaluation of second generation amiloride analogs as therapy for cystic fibrosis lung disease.

  The Journal of pharmacology and experimental therapeutics 20041201

• Transepithelial HCO3- absorption is defective in renal thick ascending limbs from Na+/H+ exchanger NHE1 null mutant mice.

  American journal of physiology. Renal physiology 20041201

• Acidification reduces mitochondrial calcium uptake in rat cardiac mitochondria.

  American journal of physiology. Heart and circulatory physiology 20041201

• Rapid nongenomic effects of 3,5,3'-triiodo-L-thyronine on the intracellular pH of L-6 myoblasts are mediated by intracellular calcium mobilization and kinase pathways.

  Endocrinology 20041201

• The neurotoxic MEC-4(d) DEG/ENaC sodium channel conducts calcium: implications for necrosis initiation.

  Nature neuroscience 20041201

• Dual therapeutic utility of proteasome modulating agents for pharmaco-gene therapy of the cystic fibrosis airway.

  Molecular therapy : the journal of the American Society of Gene Therapy 20041201

• Two types of acid-sensing ion channel currents in rat hippocampal neurons.

  Neuroscience research 20041201

• Acid-induced pain and its modulation in humans.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20041201

• Clinical significance of renal function in hypertensive patients at high risk: results from the INSIGHT trial.

  Archives of internal medicine 20041201

• Acute effects of glucose and insulin on vascular endothelium.

  Diabetologia 20041201

• Effects of Pb2+ ions on Na+ transport in the isolated skin of the toad Pleurodema thaul.

  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20041201

• Amiloride-sensitive sodium transport in lamprey red blood cells: evidence for two distinct transport pathways.

  General physiology and biophysics 20041201

• Transcellular thiocyanate transport by human airway epithelia.

  The Journal of physiology 20041115

• Acid-sensing ion channel 2 contributes a major component to acid-evoked excitatory responses in spiral ganglion neurons and plays a role in noise susceptibility of mice.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20041110

• CFTR involvement in nasal potential differences in mice and pigs studied using a thiazolidinone CFTR inhibitor.

  American journal of physiology. Lung cellular and molecular physiology 20041101

• Involvement of cytosolic Cl- in osmoregulation of alpha-ENaC gene expression.

  American journal of physiology. Renal physiology 20041101

• Defective respiratory amiloride-sensitive sodium transport predisposes to pulmonary oedema and delays its resolution in mice.

  The Journal of physiology 20041101

• Degenerin/epithelial Na+ channel proteins: components of a vascular mechanosensor.

  Hypertension (Dallas, Tex. : 1979) 20041101

• Low-renin status in therapy-resistant hypertension: a clue to efficient treatment.

  Journal of hypertension 20041101

• Effects of cholinergic m-receptor agonists on insulin release in islets from obese and lean mice of different ages: the importance of bicarbonate.

  Pancreas 20041101

• Acid-base regulation in isolated gill cells of the goldfish (Carassius auratus).

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20041101

• Transcellular and paracellular elements of salt chemosensation in toad skin.

  Chemical senses 20041101

• Behavioral comparisons of the tastes of L-alanine and monosodium glutamate in rats.

  Chemical senses 20041101

• ClC-5 chloride channel alters expression of the epithelial sodium channel (ENaC).

  The Journal of membrane biology 20041101

• Apoptosis induced by 5-(N,N-hexamethylene)-amiloride in regenerating liver after partial hepatectomy.

  European journal of pharmacology 20041025

• Capsazepine is a novel activator of the delta subunit of the human epithelial Na+ channel.

  The Journal of biological chemistry 20041022

• Intracellular pH-dependent peroxynitrite-evoked synergistic death of glucose-deprived astrocytes.

  Free radical biology & medicine 20041015

• Inhibition of bicarbonate reabsorption in the rat proximal tubule by activation of luminal P2Y1 receptors.

  American journal of physiology. Renal physiology 20041001

• Modulation of epithelial Na+ channel activity by long-chain n-3 fatty acids.

  American journal of physiology. Renal physiology 20041001

• Norepinephrine increases alveolar fluid reabsorption and Na,K-ATPase activity.

  American journal of respiratory and critical care medicine 20041001

• N-acetylcysteine inhibits Na+ absorption across human nasal epithelial cells.

  Journal of cellular physiology 20041001

• Ammonia production and secretion by S3 proximal tubule segments from acidotic mice: role of ANG II.

  American journal of physiology. Renal physiology 20041001

• Amiloride increases neuronal damage after traumatic brain injury in rats.

  Journal of the American College of Nutrition 20041001

• Evidence against the rescue of defective DeltaF508-CFTR cellular processing by curcumin in cell culture and mouse models.

  The Journal of biological chemistry 20040924

• An amiloride-sensitive H+-gated Na+ channel in Caenorhabditis elegans body wall muscle cells.

  The Journal of physiology 20040915

• A novel pathway of epithelial sodium channel activation involves a serum- and glucocorticoid-inducible kinase consensus motif in the C terminus of the channel's alpha-subunit.

  The Journal of biological chemistry 20040910

• DU145 human prostate carcinoma invasiveness is modulated by urokinase receptor (uPAR) downstream of epidermal growth factor receptor (EGFR) signaling.

  Experimental cell research 20040910

• Sodium-calcium exchanger contributes to membrane hyperpolarization of intact endothelial cells from rat aorta during acetylcholine stimulation.

  British journal of pharmacology 20040901

• Ionic interaction of amiloride and uridine 5'-triphosphate in nebulizer solutions.

  Journal of pharmaceutical sciences 20040901

• Endocardial endothelium modulates subendocardial pH(i) of rabbit papillary muscles: role of transendothelial HCO(3)(-) transport.

  Cardiovascular research 20040901

• Protein composition of apical surface fluid from the human airway cell line Calu-3: effect of ion transport mediators.

  Clinica chimica acta; international journal of clinical chemistry 20040901

• NADPH oxidase-dependent acid production in airway epithelial cells.

  The Journal of biological chemistry 20040827

• Collecting duct-specific knockout of endothelin-1 causes hypertension and sodium retention.

  The Journal of clinical investigation 20040816

• Properties of the proton-evoked currents and their modulation by Ca2+ and Zn2+ in the acutely dissociated hippocampus CA1 neurons.

  Brain research 20040813

• Steroids and exogenous gamma-ENaC subunit modulate cation channels formed by alpha-ENaC in human B lymphocytes.

  The Journal of biological chemistry 20040806

• Extracellular Na+ inhibits Na+/H+ exchange: cell shrinkage reduces the inhibition.

  American journal of physiology. Cell physiology 20040801

• Differential regulation of Na+/H+ exchange isoform activities by enteropathogenic E. coli in human intestinal epithelial cells.

  American journal of physiology. Gastrointestinal and liver physiology 20040801

• Activation of the apical Na+/H+ exchanger NHE3 by formate: a basis of enhanced fluid and electrolyte reabsorption by formate in the kidney.

  American journal of physiology. Renal physiology 20040801

• Functional role of the Na+/H+ exchanger in the regulation of cerebral arteriolar tone in rats.

  Journal of neurosurgery 20040801

• [Detection of the mRNA level of the subunits of amiloride-sensitive Na+ channel in human bronchial epithelium cells from patients with chronic obstructive pulmonary disease].

  Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20040801

• Mechanisms of low Na+-induced increase in intracellular calcium in KCl-depolarized rat cardiomyocytes.

  Molecular and cellular biochemistry 20040801

• A novel method for induction of salt appetite in rats.

  Brain research bulletin 20040730

• Maternal Bartter's syndrome in pregnancy treated by amiloride.

  European journal of obstetrics, gynecology, and reproductive biology 20040715

• Fluid transport across cultured rat alveolar epithelial cells: a novel in vitro system.

  American journal of physiology. Lung cellular and molecular physiology 20040701

• Amiloride kills malignant glioma cells independent of its inhibition of the sodium-hydrogen exchanger.

  The Journal of pharmacology and experimental therapeutics 20040701

• Intracellular acidification by inhibition of the Na+/H+-exchanger leads to caspase-independent death of cerebellar granule neurons resembling paraptosis.

  Cell death and differentiation 20040701

• Delayed shrinkage triggered by the Na+-K+ pump in terbutaline-stimulated rat alveolar type II cells.

  Experimental physiology 20040701

• PGE2 stimulates Cl- secretion in murine M-1 cortical collecting duct cells in an autocrine manner.

  Pflugers Archiv : European journal of physiology 20040701

• Biophysical and pharmacological characterization of spermatogenic T-type calcium current in mice lacking the CaV3.1 (alpha1G) calcium channel: CaV3.2 (alpha1H) is the main functional calcium channel in wild-type spermatogenic cells.

  Journal of cellular physiology 20040701

• The mammalian amiloride-insensitive non-specific salt taste receptor is a vanilloid receptor-1 variant.

  The Journal of physiology 20040701

• Despite differences between dendritic cells and Langerhans cells in the mechanism of papillomavirus-like particle antigen uptake, both cells cross-prime T cells.

  Virology 20040701

• Responses of the rat chorda tympani nerve to glutamate-sucrose mixtures.

  Chemical senses 20040701

• Effects of amiloride on potassium and calcium currents in guinea pig ventricular myocytes.

  Yao xue xue bao = Acta pharmaceutica Sinica 20040701

• Degenerin sites mediate proton activation of deltabetagamma-epithelial sodium channel.

  The Journal of biological chemistry 20040625

• CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion.

  The Journal of biological chemistry 20040625

• A glucocorticoid-induced Na+ conductance in human airway epithelial cells identified by perforated patch recording.

  The Journal of physiology 20040615

• Growth factors improve the in vivo migration of human skeletal myoblasts by modulating their endogenous proteolytic activity.

  Transplantation 20040615

• Structural determinants of the pharmacological properties of the GABAA receptor alpha6 subunit.

  The Journal of pharmacology and experimental therapeutics 20040601

• Mutations in the extracellular loop of alpha-rENaC alter sensitivity to amiloride and reactive species.

  American journal of physiology. Renal physiology 20040601

• Malnutrition impairs alveolar fluid clearance in rat lungs.

  American journal of physiology. Lung cellular and molecular physiology 20040601

• Sodium transport antagonism reduces thrombotic microangiopathy in stroke-prone spontaneously hypertensive rats.

  American journal of physiology. Renal physiology 20040601

• Patch clamp study of the UNC-105 degenerin and its interaction with the LET-2 collagen in Caenorhabditis elegans muscle.

  The Journal of physiology 20040601

• Evidence of the antiepileptic potential of amiloride with neuropharmacological benefits in rodent models of epilepsy and behavior.

  Epilepsy & behavior : E&B 20040601

• Potential new anti-human immunodeficiency virus type 1 compounds depress virus replication in cultured human macrophages.

  Antimicrobial agents and chemotherapy 20040601

• Nuclear envelope: nanoarray responsive to aldosterone.

  The Journal of membrane biology 20040601

• Characterization of Na+-permeable cation channels in LLC-PK1 renal epithelial cells.

  The Journal of biological chemistry 20040507

• Regulation of amiloride-sensitive Na(+) transport by basal nitric oxide.

  American journal of respiratory cell and molecular biology 20040501

• Molecular identity and function in transepithelial transport of K(ATP) channels in alveolar epithelial cells.

  American journal of physiology. Lung cellular and molecular physiology 20040501

• Human endothelium: target for aldosterone.

  Hypertension (Dallas, Tex. : 1979) 20040501

• The many targets of aldosterone.

  Hypertension (Dallas, Tex. : 1979) 20040501

• Inhibition of carcinogen-bioactivating cytochrome P450 1 isoforms by amiloride derivatives.

  Biochemical pharmacology 20040501

• Tumor necrosis factor induces sodium retention in diabetic rats through sequential effects on distal tubule cells.

  Kidney international 20040501

• Glutamate taste: Discrimination between the tastes of glutamate agonists and monosodium glutamate in rats.

  Chemical senses 20040501

• Flagellar motors of marine bacteria Halomonas are driven by both protons and sodium ions.

  Canadian journal of microbiology 20040501

• Upregulation of alveolar epithelial active Na+ transport is dependent on beta2-adrenergic receptor signaling.

  Circulation research 20040430

• Specific Na+ sensors are functionally expressed in a neuronal population of the median preoptic nucleus of the rat.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040421

• Vasodilation of brain surface arterioles by blockade of Na-H+ antiport and its inhibition by inhibitors of KATP channel openers.

  Brain research 20040416

• Interaction of amiloride and one of its derivatives with Vpu from HIV-1: a molecular dynamics simulation.

  FEBS letters 20040409

• Restitution of the bullfrog gastric mucosa is dependent on a DIDS-inhibitable pathway not related to HCO3- ion transport.

  American journal of physiology. Gastrointestinal and liver physiology 20040401

• Na channels in the rat connecting tubule.

  American journal of physiology. Renal physiology 20040401

• Effects of Eimeria separata infections on Na+ and Cl- transport in the rat large intestine.

  Parasitology research 20040401

• Cadmium induces both pyruvate kinase and Na+/H+ exchanger activity through protein kinase C mediated signal transduction, in isolated digestive gland cells of Mytilus galloprovincialis (L.).

  The Journal of experimental biology 20040401

• Electrochemical behavior and determination of amiloride drug in bulk form and pharmaceutical formulation at mercury electrodes.

  Journal of pharmaceutical and biomedical analysis 20040310

• Behavior and quantification studies of amiloride drug using cyclic and square-wave adsorptive stripping voltammetry at a mercury electrode.

  Journal of pharmaceutical and biomedical analysis 20040310

• Angiotensin II regulation of the Na+ pump involves the phosphatidylinositol-3 kinase and p42/44 mitogen-activated protein kinase signaling pathways in vascular smooth muscle cells.

  Endocrinology 20040301

• Interaction of androgens with cardiotonic drugs in isolated left atrium of rat.

  Pharmacology 20040301

• Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis.

  Nature medicine 20040301

• The role of Pre-H2 domains of alpha- and delta-epithelial Na+ channels in ion permeation, conductance, and amiloride sensitivity.

  The Journal of biological chemistry 20040227

• Tumor necrosis factor-alpha-induced matrix proteolytic enzyme production and basement membrane remodeling by human ovarian surface epithelial cells: molecular basis linking ovulation and cancer risk.

  Cancer research 20040215

• Identification of Murr1 as a regulator of the human delta epithelial sodium channel.

  The Journal of biological chemistry 20040213

• Epithelial Na+ channels are activated by laminar shear stress.

  The Journal of biological chemistry 20040206

• The discovery and characterization of a proton-gated sodium current in rat retinal ganglion cells.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040204

• Chemometric determination of amiloride hydrochloride, atenolol, hydrochlorothiazide and timolol maleate in synthetic mixtures and pharmaceutical formulations.

  Journal of pharmaceutical and biomedical analysis 20040204

• Downregulation of ENaC activity and expression by TNF-alpha in alveolar epithelial cells.

  American journal of physiology. Lung cellular and molecular physiology 20040201

• Amiloride-sensitive epithelial Na+ channel currents in surface cells of rat rectal colon.

  American journal of physiology. Cell physiology 20040201

• Interactions between intracellular Na+ levels and saxitoxin production in Cylindrospermopsis raciborskii T3.

  Microbiology (Reading, England) 20040201

• Photobiological modulation of cell attachment via cytochrome c oxidase.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20040201

• Foot volume increase on nifedipine is not prevented by pretreatment with diuretics.

  Journal of hypertension 20040201

• Mechanisms contributing to intracellular pH homeostasis in an immortalised human chondrocyte cell line.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20040201

• Cation-selective ion channels formed by p7 of hepatitis C virus are blocked by hexamethylene amiloride.

  FEBS letters 20040116

• NHE3 inhibition activates duodenal bicarbonate secretion in the rat.

  American journal of physiology. Gastrointestinal and liver physiology 20040101

• Hyperosmolar solution effects in guinea pig airways. II. Epithelial bioelectric responses to relative changes in osmolarity.

  The Journal of pharmacology and experimental therapeutics 20040101

• Hyperosmolar solution effects in guinea pig airways. IV. Lipopolysaccharide-induced alterations in airway reactivity and epithelial bioelectric responses to methacholine and hyperosmolarity.

  The Journal of pharmacology and experimental therapeutics 20040101

• Treatment of congenital nephrogenic diabetes insipidus with hydrochlorothiazide and amiloride in an adult patient.

  Hormone research 20040101

• Ca(2+) influx through the basolateral- and luminal membranes of colonic epithelium in neonatal rats.

  Pflugers Archiv : European journal of physiology 20040101

• A phase I trial of intranasal Moli1901 for cystic fibrosis.

  Chest 20040101

• Genetic variation in the epithelial sodium channel: a risk factor for hypertension in people of African origin.

  Advances in renal replacement therapy 20040101

• Stimulation of NHE3 in OKP cells by an autocrine mechanism.

  Nephron. Experimental nephrology 20040101

• Glutamate-induced homocysteic acid release from astrocytes: possible implication in glia-neuron signaling.

  Neuroscience 20040101

• Aldosterone signaling modifies capillary formation by human bone marrow endothelial cells.

  Vascular pharmacology 20040101

• The epithelial sodium channel in hypertension: genetic heterogeneity and implications for treatment with amiloride.

  American journal of pharmacogenomics : genomics-related research in drug development and clinical practice 20040101

• [Intracellular pH changes induced by sclerosing agents in peritoneal fibroblasts].

  Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20040101

• Differential pH and capsaicin responses of Griffonia simplicifolia IB4 (IB4)-positive and IB4-negative small sensory neurons.

  Neuroscience 20040101

• Bidirectional regulation of renal cortical Na+,K+-ATPase by protein kinase C.

  Acta biochimica Polonica 20040101

• Involvement of Na+/H+ exchanger in desmopressin-induced platelet procoagulant response.

  Acta biochimica Polonica 20040101

• Effects of nifedipine GITS and diuretics in isolated systolic hypertension--a subanalysis of the INSIGHT study.

  Blood pressure 20040101

• Control of pulmonary metastases of rat mammary cancer by inhibition of uPA and COX-2, singly and in combination.

  Clinical & experimental metastasis 20040101

• Modeling the effect of amiloride in studies of conductance of nanometer channels of synthetic track membranes.

  Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20040101

• In vivo and in vitro research on the biological effects of deuterium-depleted water: 1. Influence of deuterium-depleted water on cultured cell growth.

  Romanian journal of physiology : physiological sciences 20040101

• Physiological role of the sodium-calcium exchanger in tracheal smooth muscle of guinea pig.

  Journal of muscle research and cell motility 20040101

• Glutamate 346 of human Na+-H+ exchanger NHE1 is crucial for modulating both the affinity for Na+ and the interaction with amiloride derivatives.

  Biochemistry 20031230

• Sodium and chloride transport in soft water and hard water acclimated zebrafish (Danio rerio).

  Biochimica et biophysica acta 20031230

• Role of aquaporin and sodium channel in pleural water movement.

  Respiratory physiology & neurobiology 20031216

• Modulation of ion conductance and active transport by TGF-beta 1 in alveolar epithelial cell monolayers.

  American journal of physiology. Lung cellular and molecular physiology 20031201

• Demonstration of a functional apical sodium hydrogen exchanger in isolated rat gastric glands.

  American journal of physiology. Gastrointestinal and liver physiology 20031201

• Characterization of an amiloride binding region in the alpha-subunit of ENaC.

  American journal of physiology. Renal physiology 20031201

• Brain sodium channels and ouabainlike compounds mediate central aldosterone-induced hypertension.

  American journal of physiology. Heart and circulatory physiology 20031201

• Mechanotransduction by intraganglionic laminar endings of vagal tension receptors in the guinea-pig oesophagus.

  The Journal of physiology 20031201

• Dual effect of temperature on the human epithelial Na+ channel.

  Pflugers Archiv : European journal of physiology 20031201

• Amiloride and urinary trypsin inhibitor inhibit urothelial cancer invasion.

  European urology 20031201

• Bumetanide-induced enlargement of the intercellular space in the stria vascularis critically depends on Na+ transport.

  Hearing research 20031201

• The Na+/H+ exchange inhibitor: a new therapeutic approach for hepatic ischemia injury in rats.

  Transplantation proceedings 20031201

• The role of calcium channels in substance P-induced contractile response in the rat iris.

  Peptides 20031201

• Ca2+-dependent modulation of intracellular Mg2+ concentration with amiloride and KB-R7943 in pig carotid artery.

  The Journal of biological chemistry 20031128

• Images in clinical medicine. Hypokalemia.

  The New England journal of medicine 20031127

• Release of canine parvovirus from endocytic vesicles.

  Virology 20031125

• Airway surface liquid calcium modulates chloride permeability in the cystic fibrosis airway.

  American journal of respiratory and critical care medicine 20031115

• Transforming growth factor-beta1 decreases expression of the epithelial sodium channel alphaENaC and alveolar epithelial vectorial sodium and fluid transport via an ERK1/2-dependent mechanism.

  The Journal of biological chemistry 20031107

• Critical role for NHE1 in intracellular pH regulation in pancreatic acinar cells.

  American journal of physiology. Gastrointestinal and liver physiology 20031101

• Functional identification of the alveolar edema reabsorption activity of murine tumor necrosis factor-alpha.

  American journal of respiratory and critical care medicine 20031101

• Putative role of epithelial sodium channels (ENaC) in the afferent limb of cardio renal reflexes in rats.

  Basic research in cardiology 20031101

• Molecular and functional studies of electrogenic Na(+) transport in the distal colon and rectum of young and elderly subjects.

  Gut 20031101

• Peroxynitrite-induced cardiac depression: role of myofilament desensitization and cGMP pathway.

  Cardiovascular research 20031101

• [Inhibitive effect of curcumin and amiloride on the fibrosis of rat hepatic stellate cells induced by oxidative stress].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20031101

• Multiple epithelial Na+ channel domains participate in subunit assembly.

  American journal of physiology. Renal physiology 20031001

• Endothelin receptor blockade has an oxygen-saving effect in Dahl salt-sensitive rats with heart failure.

  American journal of physiology. Heart and circulatory physiology 20031001

• Mutations in the epithelial Na+ channel ENaC outer pore disrupt amiloride block by increasing its dissociation rate.

  Molecular pharmacology 20031001

• Secretion of macrophage urokinase plasminogen activator is dependent on proteoglycans.

  European journal of biochemistry 20031001

• The effects of endogenous diuretic and antidiuretic peptides and their second messengers in the Malpighian tubules of Tenebrio molitor: an electrophysiological study.

  Journal of insect physiology 20031001

• Recessive type of nephrogenic diabetes insipidus.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20031001

• Vanilloid receptor activation by 2- and 10-microm particles induces responses leading to apoptosis in human airway epithelial cells.

  Toxicology and applied pharmacology 20031001

• Amiloride is an ineffective conditioned stimulus in taste aversion learning in C57BL/6J and DBA/2J mice.

  Chemical senses 20031001

• Activation of apical K+ conductances by muscarinic receptor stimulation in rat distal colon: fast and slow components.

  The Journal of membrane biology 20031001

• Amiloride inhibition of glycinergic miniature IPSCs in mechanically dissociated rat spinal neurons.

  Neuroscience letters 20030925

• Arachidonic acid regulates surface expression of epithelial sodium channels.

  The Journal of biological chemistry 20030919

• Salt-evoked lingual surface potential in humans.

  Journal of neurophysiology 20030901

• Effect of altered Na+ entry on expression of apical and basolateral transport proteins in A6 epithelia.

  American journal of physiology. Renal physiology 20030901

• Epithelial Na+ channel mutants causing Liddle's syndrome retain ability to respond to aldosterone and vasopressin.

  American journal of physiology. Renal physiology 20030901

• The effect of changes in ambient oxygen concentration on the bioelectric properties of middle ear mucosa.

  American journal of physiology. Cell physiology 20030901

• May we die twice?

  Hypertension (Dallas, Tex. : 1979) 20030901

• Monosodium glutamate and sweet taste: generalization of conditioned taste aversion between glutamate and sweet stimuli in rats.

  Chemical senses 20030901

• Aspirin or amiloride for cerebral perfusion defects in cocaine dependence.

  Drug and alcohol dependence 20030820

• Bicarbonate-dependent chloride secretion in Calu-3 epithelia in response to 7,8-benzoquinoline.

  The Journal of physiology 20030815

• Amiloride inhibition of the proton-translocating NADH-quinone oxidoreductase of mammals and bacteria.

  FEBS letters 20030814

• Effects of endothelin-1 on epithelial ion transport in human airways.

  American journal of respiratory cell and molecular biology 20030801

• Mineralocorticoid regulation of epithelial Na+ channels is maintained in a mouse model of Liddle's syndrome.

  American journal of physiology. Renal physiology 20030801

• cAMP-induced changes of apical membrane potentials of confluent H441 monolayers.

  American journal of physiology. Lung cellular and molecular physiology 20030801

• A new subunit of the epithelial Na+ channel identifies regions involved in Na+ self-inhibition.

  The Journal of biological chemistry 20030801

• Evaluation of the Tg.AC assay: specificity testing with three noncarcinogenic pharmaceuticals that induce selected stress gene promoters in vitro and the inhibitory effects of solvent components.

  Toxicological sciences : an official journal of the Society of Toxicology 20030801

• Brain sodium channels and central sodium-induced increases in brain ouabain-like compound and blood pressure.

  Journal of hypertension 20030801

• Cardiac effects of amiloride and of enalapril in the spontaneously hypertensive rat.

  Journal of hypertension 20030801

• Constitutive NO synthase regulates the Na+/Ca2+ exchanger in human T cells: role of [Ca2+]i and tyrosine phosphorylation.

  Journal of cellular biochemistry 20030801

• A multicenter study of the effect of solution temperature on nasal potential difference measurements.

  Chest 20030801

• Na+ overload during ischemia and reperfusion in rat hearts: comparison of the Na+/H+ exchange blockers EIPA, cariporide and eniporide.

  Molecular and cellular biochemistry 20030801

• Modulation of the Na(+)-H(+) antiport activity by adrenaline on erythrocytes from normal and obese individuals.

  Molecular and cellular endocrinology 20030731

• Inhibition of glycine response by amiloride in rat spinal neurons.

  Neuroscience letters 20030724

• Classification of voltage-dependent Ca2+ channels in trigeminal ganglion neurons from neonatal rats.

  Life sciences 20030718

• Acidosis decreases low Ca(2+)-induced neuronal excitation by inhibiting the activity of calcium-sensing cation channels in cultured mouse hippocampal neurons.

  The Journal of physiology 20030715

• Contribution of Drosophila DEG/ENaC genes to salt taste.

  Neuron 20030703

• [3H]-DA release evoked by low pH medium and internal H+ accumulation in rat hypothalamic synaptosomes: involvement of calcium ions.

  Neurochemistry international 20030701

• CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds.

  American journal of physiology. Lung cellular and molecular physiology 20030701

• Aldosterone stimulates surface expression of NHE3 in renal proximal brush borders.

  Pflugers Archiv : European journal of physiology 20030701

• Effects of seasonal changes in food quality and food intake on the transport of sodium and butyrate across ruminal epithelium of reindeer.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20030701

• Effects of nicotinic receptor blockade on the colonic mucosal response to luminal bile acids in anaesthetized rats.

  Acta physiologica Scandinavica 20030701

• Multi-photon microscopy of cell types in the viable taste disk of the frog.

  Cell and tissue research 20030701

• Spermicidal efficacy of H2-receptor antagonists and potentiation with 2', 4'-dichlorobenzamil hydrochloride: role of intrasperm Ca2+.

  Contraception 20030701

• The effect of nitric oxide on the permeability of nasal epithelial cells from healthy and asthmatic donors.

  Medical science monitor : international medical journal of experimental and clinical research 20030701

• Ethyl isopropyl amiloride inhibits smooth muscle cell proliferation and migration by inducing apoptosis and antagonizing urokinase plasminogen activator activity.

  Canadian journal of physiology and pharmacology 20030701

• External Ni2 + and ENaC in A6 cells: Na+ current stimulation by competition at a binding site for amiloride and Na+.

  The Journal of membrane biology 20030701

• Inhibitors of Na+/H+ and Na+/Ca2+ exchange depress intracellular calcium elevation induced by ischemia/reperfusion in rat cardiac myocytes.

  Sheng li xue bao : [Acta physiologica Sinica] 20030625

• Disruptive effects of anion secretion inhibitors on airway mucus morphology in isolated perfused pig lung.

  The Journal of physiology 20030615

• Inhibition of plasminogen activation protects against ganglion cell loss in a mouse model of retinal damage.

  Molecular vision 20030612

• Temperature dependence of fluid phase endocytosis coincides with membrane properties of pig platelets.

  Biochimica et biophysica acta 20030610

• CO2 transduction in avian intrapulmonary chemoreceptors is critically dependent on transmembrane Na+/H+ exchange.

  American journal of physiology. Regulatory, integrative and comparative physiology 20030601

• Non-genomic regulation of intermediate conductance potassium channels by aldosterone in human colonic crypt cells.

  Gut 20030601

• Difficulties of introducing the National Service Framework for heart failure into general practice in the UK.

  European journal of heart failure 20030601

• Factors affecting the microclimate pH of the rat jejunum in ringer bicarbonate buffer.

  Biological & pharmaceutical bulletin 20030601

• Intracellular pH regulation in rainbow trout (Oncorhynchus mykiss) hepatocytes: the activity of sodium/proton exchange is oxygen-dependent.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20030601

• Oral amiloride treatment decreases taste sensitivity to sodium salts in C57BL/6J and DBA/2J mice.

  Chemical senses 20030601

• [Venom of Latrodectus mactans from Chile (Araneae, Theridiidae): effect on smooth muscle].

  Revista de biologia tropical 20030601

• Electrophysiological, mechanosensitive responses of Xenopus laevis oocytes to direct, isotonic increase in intracellular volume.

  Journal of neuroscience methods 20030530

• Recovery of amiloride-sensitive neural coding during regeneration of the gustatory nerve: behavioral-neural correlation of salt taste discrimination.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030515

• Serial changes in nasal potential difference and lung electrical impedance tomography at high altitude.

  Journal of applied physiology (Bethesda, Md. : 1985) 20030501

• PTH stimulates a Cl(-)-dependent and EIPA-sensitive current in chick proximal tubule cells in culture.

  American journal of physiology. Renal physiology 20030501

• Secretion of acid and base equivalents by intact distal airways.

  American journal of physiology. Lung cellular and molecular physiology 20030501

• ATP-sensitive potassium channels mediate dilatation of basilar artery in response to intracellular acidification in vivo.

  Stroke 20030501

• Contribution of cyclic-nucleotide-gated channels to the resting conductance of olfactory receptor neurons.

  Biophysical journal 20030501

• Calcium release from Synechocystis cells induced by depolarization of the plasma membrane: MscL as an outward Ca2+ channel.

  Microbiology (Reading, England) 20030501

• Apoptosis induced by Na+/H+ antiport inhibition activates the LEI/L-DNase II pathway.

  Cell death and differentiation 20030501

• Amiloride-insensitive currents of the acid-sensing ion channel-2a (ASIC2a)/ASIC2b heteromeric sour-taste receptor channel.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030501

• Role of basolateral membrane conductance in the regulation of transepithelial sodium transport across frog skin.

  Pflugers Archiv : European journal of physiology 20030501

• Measurement of nasal potential difference in mild asthmatics.

  Chest 20030501

• [Drug-induced severe jaundice].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20030501

• Acid-sensing ion channels in malignant gliomas.

  The Journal of biological chemistry 20030425

• Asymmetric organization of the pore region of the epithelial sodium channel.

  The Journal of biological chemistry 20030418

• Activation of neurons in trigeminal caudalis by noxious oral acidic or salt stimuli is not reduced by amiloride.

  Brain research 20030418

• A novel endocytic pathway induced by clustering endothelial ICAM-1 or PECAM-1.

  Journal of cell science 20030415

• Mutations of Arg440 and Gly455/Gly456 oppositely change pH sensing of Na+/H+ exchanger 1.

  The Journal of biological chemistry 20030404

• Polarized distribution of HCO3- transport in human normal and cystic fibrosis nasal epithelia.

  The Journal of physiology 20030401

• Control of hepatocyte DNA synthesis by intracellular pH and its role in the action of tumor promoters.

  Journal of cellular physiology 20030401

• A tethered bilayer sensor containing alamethicin channels and its detection of amiloride based inhibitors.

  Biosensors & bioelectronics 20030401

• Growth hormone is a weaker candidate than prolactin for the hormone responsible for the development of a larval-type feature in cultured bullfrog skin.

  The Journal of experimental biology 20030401

• Differential sensitivity of human monocytes and macrophages to ANP: a role of intracellular pH on reactive oxygen species production through the phospholipase involvement.

  Journal of leukocyte biology 20030401

• A polycystin-2-like large conductance cation channel in rat left ventricular myocytes.

  Cardiovascular research 20030401

• Amiloride reduces stroke and renalinjury in stroke-prone hypertensive rats.

  American journal of hypertension 20030401

• Effect of aquaporin-1 deletion on pleural fluid transport.

  Acta pharmacologica Sinica 20030401

• Treatment of lithium-induced diabetes insipidus with amiloride.

  Pharmacotherapy 20030401

• Inhibition of erythrocyte cation channels and apoptosis by ethylisopropylamiloride.

  Naunyn-Schmiedeberg's archives of pharmacology 20030401

• Identification and characterization of the imidazoline I2b-binding sites in the hamster brown adipose tissue as a study model for imidazoline receptors.

  Archives of physiology and biochemistry 20030401

• Early changes in metabolism of leukemic cell lines upon induction of apoptosis by cytotoxic drugs.

  European journal of pharmacology 20030328

• Role of Na+/H+ exchanger in acetylcholine-mediated pulmonary artery contraction of spontaneously hypertensive rats.

  European journal of pharmacology 20030319

• Nasal epithelium potential difference at high altitude (4,559 m): evidence for secretion.

  American journal of respiratory and critical care medicine 20030315

• Sodium transport across the chorioallantoic membrane of porcine placenta involves the epithelial sodium channel (ENaC).

  The Journal of physiology 20030315

• Effects of purinergic stimulation, CFTR and osmotic stress on amiloride-sensitive Na+ transport in epithelia and Xenopus oocytes.

  The Journal of membrane biology 20030315

• Effects of demethylzeylasteral and celastrol on spermatogenic cell Ca2+ channels and progesterone-induced sperm acrosome reaction.

  European journal of pharmacology 20030307

• Adenosine stimulates anion secretion across cultured and native adult human vas deferens epithelia.

  Biology of reproduction 20030301

• Outcomes with nifedipine GITS or Co-amilozide in hypertensive diabetics and nondiabetics in Intervention as a Goal in Hypertension (INSIGHT).

  Hypertension (Dallas, Tex. : 1979) 20030301

• Inhibition of apical Na+/H+ exchangers on the macula densa cells augments tubuloglomerular feedback.

  Hypertension (Dallas, Tex. : 1979) 20030301

• A novel early chorioallantoic membrane assay demonstrates quantitative and qualitative changes caused by antiangiogenic substances.

  The Journal of laboratory and clinical medicine 20030301

• Age related decreases in neural sensitivity to NaCl in SHR-SP.

  The Journal of veterinary medical science 20030301

• Differential allosteric modulation by amiloride analogues of agonist and antagonist binding at A(1) and A(3) adenosine receptors.

  Biochemical pharmacology 20030215

• Localization and characterization of phenamil-sensitive Na+ influx in isolated rainbow trout gill epithelial cells.

  The Journal of experimental biology 20030201

• Modulation of sodium transport in fetal alveolar epithelial cells by oxygen and corticosterone.

  American journal of physiology. Lung cellular and molecular physiology 20030201

• Effects of extracellular Na+ and Ca2+ ions and Ca2+ channel modulators on the cell-associated activity of 99mTc-MIBI and 99mTc-tetrofosmin in tumour cells.

  Nuclear medicine communications 20030201

• Noninvasive assessment of aqueous humor turnover in the mouse eye.

  Investigative ophthalmology & visual science 20030201

• Antifibrogenic effects of canrenone, an antialdosteronic drug, on human hepatic stellate cells.

  Gastroenterology 20030201

• Intracellular sodium hydrogen exchange inhibition and clinical myocardial protection.

  The Annals of thoracic surgery 20030201

• Clinical trial experience around the globe: focus on calcium-channel blockers.

  Clinical cardiology 20030201

• Regulatory role of extracellular Na+ and Ca2+ ions in nerve growth factor induced histamine secretion from rat mast cells.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030201

• Involvement of Na/Ca exchange and intracellular mobilized Ca2+ in Na,K-pump-mediated control of depression of the cholinosensitivy of common snail neurons [correction of neorons] using a cellular analog of habituation.

  Neuroscience and behavioral physiology 20030201

• Cation channels trigger apoptotic death of erythrocytes.

  Cell death and differentiation 20030201

• Increasing concentration of inhaled saline with or without amiloride: effect on mucociliary clearance in normal subjects.

  American journal of respiratory and critical care medicine 20030115

• Epithelial sodium channel activity in detergent-resistant membrane microdomains.

  American journal of physiology. Renal physiology 20030101

• Epidermal growth factor inhibits amiloride-sensitive sodium absorption in renal collecting duct cells.

  American journal of physiology. Renal physiology 20030101

• Functional polymorphisms in the mineralocorticoid receptor and amirolide-sensitive sodium channel genes in a patient with sporadic pseudohypoaldosteronism.

  Human genetics 20030101

• Effect of protein kinase C activation on Na+-H+ exchange in erythrocytes of frog Rana temporaria.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20030101

• Differential response properties of IB(4)-positive and -negative unmyelinated sensory neurons to protons and capsaicin.

  Journal of neurophysiology 20030101

• ENaC-CFTR interactions: the role of electrical coupling of ion fluxes explored in an epithelial cell model.

  Pflugers Archiv : European journal of physiology 20030101

• Modified method to measure nasal potential difference.

  Clinical chemistry and laboratory medicine 20030101

• Evidence for a carrier-mediated mechanism for thiamine transport to human jejunal basolateral membrane vesicles.

  Digestive diseases and sciences 20030101

• Intracellular pH regulation in U937 human monocytes: roles of V-ATPase and Na+/H+ exchange.

  Immunobiology 20030101

• Endolymphatic sodium homeostasis by Reissner's membrane.

  Neuroscience 20030101

• Expression of oligomeric amiloride-sensitive epithelial sodium channel in Sf9 insect cells.

  Methods in molecular biology (Clifton, N.J.) 20030101

• Electrophysiological properties of the Plasmodium Falciparum-induced cation conductance of human erythrocytes.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20030101

• Effects of amiloride and bumetanide on ion transport in the caecum of rabbit.

  Polish journal of pharmacology 20030101

• Effect of amiloride and bumetanide on ionic currents in the epithelium of caecum from starved rabbits.

  Polish journal of pharmacology 20030101

• [Activation of the Na/H exchange in erythrocytes of the frog Rana ridibunda].

  Zhurnal evoliutsionnoi biokhimii i fiziologii 20030101

• [The role of protein kinase C in Na+ transport regulation in the skin of adult frogs and tadpoles of Rana temporaria].

  Tsitologiia 20030101

• Dependence of Plasmodium falciparum in vitro growth on the cation permeability of the human host erythrocyte.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20030101

• Influence of murine renal sexual dimorphism on amiloride-induced hyperkalemia.

  Nephron. Physiology 20030101

• External nickel inhibits epithelial sodium channel by binding to histidine residues within the extracellular domains of alpha and gamma subunits and reducing channel open probability.

  The Journal of biological chemistry 20021220

• Simultaneous determination of amiloride and furosemide in pharmaceutical formulations by first digital derivative spectrophotometry.

  International journal of pharmaceutics 20021205

• Altering airway surface liquid volume: inhalation therapy with amiloride and hyperosmotic agents.

  Advanced drug delivery reviews 20021205

• Responsiveness of hypercalciuria to thiazide in Dent's disease.

  Journal of the American Society of Nephrology : JASN 20021201

• Basolateral adrenoceptor activation mediates noradrenaline-induced Cl- secretion in M-1 mouse cortical collecting duct cells.

  Pflugers Archiv : European journal of physiology 20021201

• The role of Na+/H+ exchange in the efficacy of multidose hypothermic cardioplegia in immature rabbit hearts.

  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20021201

• Racial difference in the activity of the amiloride-sensitive epithelial sodium channel.

  Hypertension (Dallas, Tex. : 1979) 20021201

• Hypokalaemia and hyponatraemia due to indapamide.

  Prescrire international 20021201

• The route of bacterial uptake by macrophages influences the repertoire of epitopes presented to CD4 T cells.

  European journal of immunology 20021201

• Functional visualization of the excretory system of adult Schistosoma mansoni by the fluorescent marker resorufin.

  Parasitology 20021201

• Terbutaline-induced triphasic changes in volume of rat alveolar type II cells: the role of cAMP.

  The Japanese journal of physiology 20021201

• Potentiation of spermicidal activity of 2',4'-dichlorobenzamil by lidocaine.

  Indian journal of experimental biology 20021201

• Sodium-proton exchange in crayfish.

  Biochimica et biophysica acta 20021113

• Annelid epithelia as models for electrogenic Na+ transport.

  Biochimica et biophysica acta 20021113

• Sodium-dependent copper uptake across epithelia: a review of rationale with experimental evidence from gill and intestine.

  Biochimica et biophysica acta 20021113

• Where have all the Na+ channels gone? In search of functional ENaC in exocrine pancreas.

  Biochimica et biophysica acta 20021113

• Simultaneous determination of amiloride hydrochloride and hydrochlorothiazide in synthetic samples and pharmaceutical formulations by multivariate analysis of spectrophotometric data.

  Journal of pharmaceutical and biomedical analysis 20021107

• Apical H(+)/base transporters mediating bicarbonate absorption and pH(i) regulation in the OMCD.

  American journal of physiology. Renal physiology 20021101

• ENaC plays a role in regulated antibody secretion by hybridomas.

  American journal of physiology. Cell physiology 20021101

• Increasing plasma potassium with amiloride shortens the QT interval and reduces ventricular extrasystoles but does not change endothelial function or heart rate variability in chronic heart failure.

  Heart (British Cardiac Society) 20021101

• Selected contribution: limiting Na(+) transport rate in airway epithelia from alpha-ENaC transgenic mice: a model for pulmonary edema.

  Journal of applied physiology (Bethesda, Md. : 1985) 20021101

• Cytosolic pH and the inflammatory microenvironment modulate cell death in human neutrophils after phagocytosis.

  Blood 20021101

• Developmental changes in the management of acid loads during preimplantation mouse development.

  Biology of reproduction 20021101

• The urokinase plasminogen activator: an interesting way to improve myoblast migration following their transplantation.

  Experimental cell research 20021101

• Rearing on basal or high dietary NaCl modifies chorda tympani nerve responses in rats.

  Physiology & behavior 20021101

• Pulmonary oedema fluid induces non-alpha-ENaC-dependent Na(+) transport and fluid absorption in the distal lung.

  The Journal of physiology 20021015

• Amiloride-blockable acid-sensing ion channels are leading acid sensors expressed in human nociceptors.

  The Journal of clinical investigation 20021015

• Effects of metabolite uptake on proton-equivalent elimination by two species of deep-sea vestimentiferan tubeworm, Riftia pachyptila and Lamellibrachia cf luymesi: proton elimination is a necessary adaptation to sulfide-oxidizing chemoautotrophic symbionts.

  The Journal of experimental biology 20021001

• Calcium channel blockers inhibit galvanotaxis in human keratinocytes.

  Journal of cellular physiology 20021001

• Epithelial Na channels and short-term renal response to salt deprivation.

  American journal of physiology. Renal physiology 20021001

• Na(+)-K(+)-ATPase activity in alveolar epithelial cells increases with cyclic stretch.

  American journal of physiology. Lung cellular and molecular physiology 20021001

• Role of PKCalpha in feedback regulation of Na(+) transport in an electrically tight epithelium.

  American journal of physiology. Cell physiology 20021001

• Amiloride-sensitive sodium current in everted Ambystoma initial collecting tubule: short-term insulin effects.

  American journal of physiology. Cell physiology 20021001

• Characterization of a Na(+)-Ca(2+) exchanger in podocytes.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20021001

• Na(+)/Ca(2+) exchanger in porcine oocytes.

  Biology of reproduction 20021001

• Time-dependent effect of pneumonectomy on alveolar epithelial fluid clearance in rat lungs.

  The Journal of thoracic and cardiovascular surgery 20021001

• Cloned bullfrog skin sodium (fENaC) and xENaC subunits hybridize to form functional sodium channels.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20021001

• Characterization of ion and fluid transport in human bronchioles.

  American journal of respiratory cell and molecular biology 20021001

• Aspergillus fumigatus causes in vitro electrophysiological and morphological modifications in human nasal epithelial cells.

  Histology and histopathology 20021001

• Amitriptyline has a dual effect on the conductive properties of the epithelial Na channel.

  The Journal of pharmacy and pharmacology 20021001

• No evidence for inhibition of ENaC through CFTR-mediated release of ATP.

  Biochimica et biophysica acta 20020920

• Coiled body heterogeneity induced by G(1) arrest with amiloride + bumetanide.

  Experimental cell research 20020910

• Plasmalemmal H+ extruders in mammalian alveolar macrophages.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20020901

• Biphasic regulation of plasminogen activator/inhibitor by LDL in mesangial cells.

  American journal of physiology. Renal physiology 20020901

• Effects of ion transport inhibitors on MCh-mediated secretion from porcine airway submucosal glands.

  Journal of applied physiology (Bethesda, Md. : 1985) 20020901

• Transecting the gustatory branches of the facial nerve impairs NH(4)Cl vs. KCl discrimination in rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20020901

• Interactions between the new cytotoxic drug CHS 828 and amiloride and mitomycin C in a human tumour cell line and in tumour cells from patients.

  Chemotherapy 20020901

• The major route for absorption of fluid from the pleural space.

  Lymphology 20020901

• Effect of amiloride in human and sheep parietal pleura.

  Respiratory physiology & neurobiology 20020830

• Urokinase is required for the formation of mactinin, an alpha-actinin fragment that promotes monocyte/macrophage maturation.

  Biochimica et biophysica acta 20020819

• The NHX family of Na+-H+ exchangers in Caenorhabditis elegans.

  The Journal of biological chemistry 20020809

• NHE blockade inhibits chemokine production and NF-kappaB activation in immunostimulated endothelial cells.

  American journal of physiology. Cell physiology 20020801

• Loss of cell volume regulation during metabolic inhibition in renal epithelial cells (A6): role of intracellular pH.

  American journal of physiology. Cell physiology 20020801

• Influence of ANG II on cytoplasmic sodium in cultured rabbit nonpigmented ciliary epithelium.

  American journal of physiology. Cell physiology 20020801

• Glucose stimulates O2 consumption, NOS, and Na/H exchange in diabetic rat proximal tubules.

  American journal of physiology. Renal physiology 20020801

• Liquid secretion inhibitors reduce mucociliary transport in glandular airways.

  American journal of physiology. Lung cellular and molecular physiology 20020801

• Role of luminal ATP in regulating electrogenic Na(+) absorption in guinea pig distal colon.

  American journal of physiology. Gastrointestinal and liver physiology 20020801

• Involvement of Na(+)/Ca(2+) exchanger in endothelial NO production and endothelium-dependent relaxation.

  American journal of physiology. Heart and circulatory physiology 20020801

• Liddle syndrome in a newborn infant.

  Pediatric nephrology (Berlin, Germany) 20020801

• Electrogenic ion transport in the intestine of the Australian common brushtail possum, Trichosurus vulpecula: indications of novel transport patterns in a marsupial.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20020801

• Aldosterone does not regulate amiloride-sensitive Na(+) transport in the colon of the Australian common brushtail possum, Trichosurus vulpecula.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20020801

• Activation of CFTR Cl(-) channel by tyrphostins via a protein tyrosine kinase-independent pathway in forskolin-stimulated renal epithelial A6 cells.

  Life sciences 20020726

• Cytostatic potential of novel agents that inhibit the regulation of intracellular pH.

  British journal of cancer 20020715

• Hypoxia activates a background conductance in freshly isolated pulmonary arterial endothelial cells of the rat.

  FEBS letters 20020703

• Apical Na+/H+ exchange near the base of mouse colonic crypts.

  American journal of physiology. Cell physiology 20020701

• Expression and function of sodium transporters in two opossum kidney cell clonal sublines.

  American journal of physiology. Renal physiology 20020701

• Na+/H+ exchanger blockade inhibits enterocyte inflammatory response and protects against colitis.

  American journal of physiology. Gastrointestinal and liver physiology 20020701

• Interferon-alpha (Intron A) upregulates urokinase-type plasminogen activator receptor gene expression.

  Cancer immunology, immunotherapy : CII 20020701

• Amiloride and KB-R7943 in outward Na+ /Ca2+ exchange current in guinea pig ventricular myocytes.

  Journal of cardiovascular pharmacology 20020701

• Acid-activated cation currents in rat vallate taste receptor cells.

  Journal of neurophysiology 20020701

• Mitochondrial damage during ischemia determines post-ischemic contractile dysfunction in perfused rat heart.

  Journal of molecular and cellular cardiology 20020701

• Collecting duct function in liver cirrhotic rats with early sodium retention.

  Acta physiologica Scandinavica 20020701

• Amiloride, a specific drug for hypertension in black people with T594M variant?

  Hypertension (Dallas, Tex. : 1979) 20020701

• Brain sodium channels mediate increases in brain 'ouabain' and blood pressure in Dahl S rats.

  Hypertension (Dallas, Tex. : 1979) 20020701

• Elicitor-activated phospholipase A(2) generates lysophosphatidylcholines that mobilize the vacuolar H(+) pool for pH signaling via the activation of Na(+)-dependent proton fluxes.

  The Plant cell 20020701

• Mechanosensory transduction of vagal and baroreceptor afferents revealed by study of isolated nodose neurons in culture.

  Autonomic neuroscience : basic & clinical 20020628

• Enhancement of Ca(2+) transients and contraction of single ventricular myocytes of rats by 5-(N,N-dimethyl) amiloride.

  Sheng li xue bao : [Acta physiologica Sinica] 20020625

• Chemometric resolution of a mixture containing hydrochlorothiazide and amiloride by absorption and derivative spectrophotometry.

  Journal of pharmaceutical and biomedical analysis 20020620

• Metabolic activation of A549 human airway epithelial cells by organic dust: a study based on microphysiometry.

  Life sciences 20020607

• Synthesis and biological evaluation of aroylguanidines related to amiloride as inhibitors of the human platelet Na(+)/H(+) exchanger.

  Bioorganic & medicinal chemistry 20020601

• Amiloride inhibition of gamma-aminobutyric acid(A) receptors depends upon the alpha subunit subtype.

  Molecular pharmacology 20020601

• Inhibitors of NHE-1 Na+/H+ exchange reduce mouse intraocular pressure.

  Investigative ophthalmology & visual science 20020601

• DRASIC contributes to pH-gated currents in large dorsal root ganglion sensory neurons by forming heteromultimeric channels.

  Journal of neurophysiology 20020601

• Intrinsic H(+) ion mobility in the rabbit ventricular myocyte.

  The Journal of physiology 20020515

• Intestinal NaCl transport in NHE2 and NHE3 knockout mice.

  American journal of physiology. Gastrointestinal and liver physiology 20020501

• EGF promotes gastric mucosal restitution by activating Na(+)/H(+) exchange of epithelial cells.

  American journal of physiology. Gastrointestinal and liver physiology 20020501

• Angiotensin II directly stimulates ENaC activity in the cortical collecting duct via AT(1) receptors.

  Journal of the American Society of Nephrology : JASN 20020501

• Proton-gated channels in PC12 cells.

  Journal of neurophysiology 20020501

• Mechanisms for the inhibition of amiloride-sensitive Na+ absorption by extracellular nucleotides in mouse trachea.

  Pflugers Archiv : European journal of physiology 20020501

• Calcium-pump inhibitors induce functional surface expression of Delta F508-CFTR protein in cystic fibrosis epithelial cells.

  Nature medicine 20020501

• Discrimination between the tastes of sucrose and monosodium glutamate in rats.

  Chemical senses 20020501

• Model study of toluene diisocyanate effect on transepithelial ion transport.

  Medical science monitor : international medical journal of experimental and clinical research 20020501

• Effect of hydrochloric acid, pepsin, or taurocholate on bioelectric properties of gastric squamous mucosa in horses.

  American journal of veterinary research 20020501

• Chronic hypobaric hypoxia effects on rat colon in vitro sensitivity to acute hypoxia and amiloride.

  Digestive diseases and sciences 20020501

• Erythrocyte Na+,K+-ATPase and nasal potential in pseudohypoaldosteronism.

  Clinical endocrinology 20020501

• Effects of Ca(2+) channel blockers on amiloride-sensitive Na(+) permeable channels and Na(+) transport in fetal rat alveolar type II epithelium.

  Biochemical pharmacology 20020415

• Plasminogen activator activity in cortical granules of bovine oocytes during in vitro maturation.

  Theriogenology 20020415

• Acid secretion and proton conductance in human airway epithelium.

  American journal of physiology. Cell physiology 20020401

• Beta-adrenergic regulation of amiloride-sensitive lung sodium channels.

  American journal of physiology. Lung cellular and molecular physiology 20020401

• Glucocorticoid-stimulated lung epithelial Na(+) transport is associated with regulated ENaC and sgk1 expression.

  American journal of physiology. Lung cellular and molecular physiology 20020401

• Ca(2+)-dependent stimulation of alveolar fluid clearance in near-term fetal guinea pigs.

  American journal of physiology. Lung cellular and molecular physiology 20020401

• cAMP regulation of Cl(-) and HCO(-)(3) secretion across rat fetal distal lung epithelial cells.

  American journal of physiology. Lung cellular and molecular physiology 20020401

• Hypoxia decreases active Na transport across primary rat alveolar epithelial cell monolayers.

  American journal of physiology. Lung cellular and molecular physiology 20020401

• Basolateral membrane Cl(-)-, Na(+)-, and K(+)-coupled base transport mechanisms in rat MTALH.

  American journal of physiology. Renal physiology 20020401

• Acute hypertension provokes internalization of proximal tubule NHE3 without inhibition of transport activity.

  American journal of physiology. Renal physiology 20020401

• Mechanism of n-butyrate uptake in the human proximal colonic basolateral membranes.

  American journal of physiology. Gastrointestinal and liver physiology 20020401

• Steroids modulate transepithelial resistance and Na(+) absorption across cultured porcine vas deferens epithelia.

  Biology of reproduction 20020401

• Determinants of intracellular pH in gas gland cells of the swimbladder of the European eel Anguilla anguilla.

  The Journal of experimental biology 20020401

• Copper uptake across rainbow trout gills: mechanisms of apical entry.

  The Journal of experimental biology 20020401

• The effect of amiloride on the in vivo effective permeability of amoxicillin in human jejunum: experience from a regional perfusion technique.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20020401

• Differences in mechano-transducer channel kinetics underlie tonotopic distribution of fast adaptation in auditory hair cells.

  Journal of neurophysiology 20020401

• Regulation of firing response gain by calcium-dependent mechanisms in vestibular nucleus neurons.

  Journal of neurophysiology 20020401

• Effects of anion and cation inhibitors and carbonic anhydrase inhibitors upon the activity of the gypsy moth (Lepidoptera: Lymantriidae) nucleo-polyhedrovirus.

  Journal of economic entomology 20020401

• L-arginine potentiates negative inotropic and metabolic effects to myocardium partly through the amiloride sensitive mechanism.

  The Japanese journal of physiology 20020401

• Rat ENaC expressed in Xenopus laevis oocytes is activated by cAMP and blocked by Ni(2+).

  FEBS letters 20020327

• Cloning and expression of a chloride-dependent Na+-H+ exchanger.

  The Journal of biological chemistry 20020322

• Genistein restores functional interactions between Delta F508-CFTR and ENaC in Xenopus oocytes.

  The Journal of biological chemistry 20020315

• Anionic phospholipids regulate native and expressed epithelial sodium channel (ENaC).

  The Journal of biological chemistry 20020308

• Hyponatraemia and hypokalaemia due to indapamide.

  The Medical journal of Australia 20020304

• sgk: an essential convergence point for peptide and steroid hormone regulation of ENaC-mediated Na+ transport.

  American journal of physiology. Cell physiology 20020301

• Mechanism and regulation of vitamin B(6) uptake by renal tubular epithelia: studies with cultured OK cells.

  American journal of physiology. Renal physiology 20020301

• Enhanced ammonia secretion by proximal tubules from mice receiving NH(4)Cl: role of angiotensin II.

  American journal of physiology. Renal physiology 20020301

• Stimulation of chloride secretion by baicalein in isolated rat distal colon.

  American journal of physiology. Gastrointestinal and liver physiology 20020301

• Dehydroascorbic acid uptake by coronary artery smooth muscle: effect of intracellular acidification.

  The Biochemical journal 20020301

• Uptake and processing of Chlamydia trachomatis by human dendritic cells.

  European journal of immunology 20020301

• Twenty-four hour ambulatory blood pressure in the International Nifedipine GITS Study Intervention as a Goal in Hypertension Treatment (INSIGHT).

  Journal of hypertension 20020301

• Ionic mechanisms of regulatory volume increase (RVI) in the human hepatoma cell-line HepG2.

  Pflugers Archiv : European journal of physiology 20020301

• Activity modes and modulation of the peptide-gated Na(+) channel of Helix neurones.

  Pflugers Archiv : European journal of physiology 20020301

• Influence of voltage and extracellular Na(+) on amiloride block and transport kinetics of rat epithelial Na(+) channel expressed in Xenopus oocytes.

  Pflugers Archiv : European journal of physiology 20020301

• Spectrofluorometric resolution of closely overlapping drug mixtures using chemometrics methods.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20020301

• Colour reactions of PH. EUR. for identification of drugs using 1,3-dibromo-5,5-dimethylhydantoin (DBH) instead of elemental bromine. Analytical methods of pharmacopoeias with DBH in respect to environmental and economical concern, Part 10.

  Die Pharmazie 20020301

• Role of carbon dioxide and ion transport in the formation of sub-embryonic fluid by the blastoderm of the Japanese quail.

  British poultry science 20020301

• Magnesium transport through the basal plasma membrane of larval malpighian tubules of Drosophila hydei studied by electron probe X-ray microanalysis.

  Magnesium research 20020301

• Amiloride derivatives block ion channel activity and enhancement of virus-like particle budding caused by HIV-1 protein Vpu.

  European biophysics journal : EBJ 20020301

• Clomipramine induces the opening of Na+ channels in the frog skin epithelium.

  Pharmacology & toxicology 20020301

• MEC-2 regulates C. elegans DEG/ENaC channels needed for mechanosensation.

  Nature 20020227

• Mechanosensitive ion channels in cultured sensory neurons of neonatal rats.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20020215

• Basolateral PAR-2 receptors mediate KCl secretion and inhibition of Na+ absorption in the mouse distal colon.

  The Journal of physiology 20020215

• Amiloride inhibits proximal tubular reabsorption in conscious euvolemic rats.

  European journal of pharmacology 20020215

• Activation of NKCC1 by hyperosmotic stress in human tracheal epithelial cells involves PKC-delta and ERK.

  Biochimica et biophysica acta 20020213

• Interleukin-13 induces a hypersecretory ion transport phenotype in human bronchial epithelial cells.

  American journal of physiology. Lung cellular and molecular physiology 20020201

• Lidocaine induces a reversible decrease in alveolar epithelial fluid clearance in rats.

  Anesthesiology 20020201

• Antileukemia activity of perillyl alcohol (POH): uncoupling apoptosis from G0/G1 arrest suggests that the primary effect of POH on Bcr/Abl-transformed cells is to induce growth arrest.

  Leukemia 20020201

• Ischemic preconditioning and Na+/H+ exchange inhibition improve reperfusion ion homeostasis.

  The Annals of thoracic surgery 20020201

• Attenuation of cardiac fibrosis by pirfenidone and amiloride in DOCA-salt hypertensive rats.

  British journal of pharmacology 20020201

• Membrane effects of toxins isolated from a cyanobacterium, Cylindrospermopsis raciborskii, on identified molluscan neurones.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020201

• Properties of a sodium channel (Na(x)) activated by strong depolarization of Xenopus oocytes.

  The Journal of membrane biology 20020201

• Ion transport across posterior gills of hyperosmoregulating shore crabs (Carcinus maenas): amiloride blocks the cuticular Na(+) conductance and induces current-noise.

  The Journal of experimental biology 20020201

• The effect of amiloride on operantly conditioned performance in an NaCl taste detection task and NaCl preference in C57BL/6J mice.

  Behavioral neuroscience 20020201

• Functional effects of a monoclonal antibody on mechanoelectrical transduction in outer hair cells.

  Hearing research 20020201

• Intracellular pH regulation in U-2 OS human osteosarcoma cells transfected with P-glycoprotein.

  Biochimica et biophysica acta 20020130

• Involvement of phosphorylation of Tyr-31 and Tyr-118 of paxillin in MM1 cancer cell migration.

  International journal of cancer 20020120

• Regulation of intracellular pH in Calu-3 human airway cells.

  The Journal of physiology 20020115

• Expression of a sodium bicarbonate cotransporter in human parotid salivary glands.

  Archives of oral biology 20020101

• Effect of eccentric contraction-induced injury on force and intracellular pH in rat skeletal muscles.

  Journal of applied physiology (Bethesda, Md. : 1985) 20020101

• Amiloride blockades lipopolysaccharide-induced proinflammatory cytokine biosynthesis in an IkappaB-alpha/NF-kappaB-dependent mechanism. Evidence for the amplification of an antiinflammatory pathway in the alveolar epithelium.

  American journal of respiratory cell and molecular biology 20020101

• Excitation and adaptation in the detection of hydrogen ions by taste receptor cells: a role for cAMP and Ca(2+).

  Journal of neurophysiology 20020101

• Evaluating routine diuretics after coronary surgery: a prospective randomized controlled trial.

  The Annals of thoracic surgery 20020101

• Cardiomyocyte intracellular calcium and cardiac dysfunction after burn trauma.

  Critical care medicine 20020101

• [Effects of T-type calcium channel blockers on spontaneous meiotic maturation of mouse ovarian oocytes in vitro].

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20020101

• Receptor-bound uPA is reversibly protected from inhibition by low molecular weight inhibitors.

  Cell biology international 20020101

• [Modification of damaging effect of ultraviolet radiation on peritoneal macrophage membranes in mice].

  Radiatsionnaia biologiia, radioecologiia 20020101

• Long-term protection in at-risk hypertensive patients--a role for nifedipine GITS?

  Blood pressure 20020101

• Na+/H+ exchange in primary, secondary and n-butyrate-treated cultures of ruminal epithelial cells: short communication.

  Acta veterinaria Hungarica 20020101

• Patch-clamp studies on epithelial sodium channels in salivary duct cells.

  Cell biochemistry and biophysics 20020101

• Ion exchangers mediating NaCl transport in the renal proximal tubule.

  Cell biochemistry and biophysics 20020101

• The effects of fluticasone propionate on nasal epithelial potential difference.

  American journal of rhinology 20020101

• The impact of phorbol ester on the regulation of amiloride-sensitive epithelial sodium channel in alveolar type ii epithelial cells.

  Experimental lung research 20020101

• Volume independent stimulation of renin secretion by a single dose of amiloride in man.

  Arzneimittel-Forschung 20020101

• Vacuole formation in mast cells responding to osmotic stress and to F-actin disassembly.

  Cell biology international 20020101

• Na(+)/H(+) exchanger activity and dopamine D(1)-like receptor function in two opossum kidney cell clonal sublines.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20020101

• [Inhibiting and stimulating effect of amiloride on potential-dependent cation channels in K562 cells].

  Tsitologiia 20020101

• [Effect of a hypertonic sucrose solution and 5-(N,N-hexamethylene)-amiloride on receptor-mediated and liquid-phase endocytosis].

  Tsitologiia 20020101

• Modulation of the phototoxic effect of hypericin in human leukemia CEM cell line by N-ethylmaleimide, amiloride and omeprazole.

  Physiological research 20020101

• [Regulation of posttetanic increase in choline sensitivity in Helix neurons by Na,K-pump: the role of Na/Ca-exchange and of mobilized calcium].

  Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20020101

• The interleukin-2-deficient mouse model.

  Pathobiology : journal of immunopathology, molecular and cellular biology 20020101

• Effect of capsaicin on ion transport in the caecum of rabbits.

  Polish journal of pharmacology 20020101

• Acidic stimuli activates two distinct pathways in taste receptor cells from rat fungiform papillae.

  Brain research 20011227

• Short term effect of aldosterone on Na,K-ATPase cell surface expression in kidney collecting duct cells.

  The Journal of biological chemistry 20011214

• In vivo fluorescence measurement of Na(+) concentration in the pericryptal space of mouse descending colon.

  American journal of physiology. Cell physiology 20011201

• Role of JNK in hypertonic activation of Cl(-)-dependent Na(+)/H(+) exchange in Xenopus oocytes.

  American journal of physiology. Cell physiology 20011201

• Regulation of K(+) current in human airway epithelial cells by exogenous and autocrine adenosine.

  American journal of physiology. Cell physiology 20011201

• Role of NHE isoforms in mediating bicarbonate reabsorption along the nephron.

  American journal of physiology. Renal physiology 20011201

• Colonic H(+)-K(+)-ATPase in K(+) conservation and electrogenic Na(+) absorption during Na(+) restriction.

  American journal of physiology. Gastrointestinal and liver physiology 20011201

• Developmental changes in intracellular pH regulation in medullary neurons of the rat.

  American journal of physiology. Regulatory, integrative and comparative physiology 20011201

• Low-voltage-activated calcium channels are not involved in capacitation and biological response to progesterone in human sperm.

  International journal of andrology 20011201

• Enhancement of delta aminolevulinic acid-photodynamic therapy in vivo by decreasing tumor pH with glucose and amiloride.

  The Laryngoscope 20011201

• Neurotransmitter-stimulated ion transport across cultured bovine mammary epithelial cell monolayers.

  Journal of dairy science 20011201

• Cell membrane transport of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the liver and systemic bioavailability.

  Biochemical and biophysical research communications 20011123

• Basolateral K+ conductance establishes driving force for cation absorption by outer sulcus epithelial cells.

  The Journal of membrane biology 20011115

• SRC family kinases mediate epithelial Na+ channel inhibition by endothelin.

  The Journal of biological chemistry 20011109

• Fatty acid modulation and sequence identity of fetal guinea pig alveolar type II cell amiloride-sensitive Na+ channel.

  Biochemical and biophysical research communications 20011102

• Chlorzoxazone or 1-EBIO increases Na(+) absorption across cystic fibrosis airway epithelial cells.

  American journal of physiology. Lung cellular and molecular physiology 20011101

• Partial correction of defective Cl(-) secretion in cystic fibrosis epithelial cells by an analog of squalamine.

  American journal of physiology. Lung cellular and molecular physiology 20011101

• Examining basal chloride transport using the nasal potential difference response in a murine model.

  American journal of physiology. Lung cellular and molecular physiology 20011101

• Hyperactive ENaC identifies hypertensive individuals amenable to amiloride therapy.

  American journal of physiology. Cell physiology 20011101

• Effect of short-term cyclic stretch on sodium pump activity in aortic smooth muscle cells.

  American journal of physiology. Heart and circulatory physiology 20011101

• Propofol protection of sodium-hydrogen exchange activity sustains glutamate uptake during oxidative stress.

  Anesthesia and analgesia 20011101

• Release of non-neuronal acetylcholine from the isolated human placenta is mediated by organic cation transporters.

  British journal of pharmacology 20011101

• Re-evaluating the Na(+) conductance of adult rat alveolar type II pneumocytes: evidence for the involvement of cGMP-activated cation channels.

  The Journal of physiology 20011101

• A novel pharmacological probe links the amiloride-insensitive NaCl, KCl, and NH(4)Cl chorda tympani taste responses.

  Journal of neurophysiology 20011101

• Evidence supporting a role for KCl cotransporter in the thick ascending limb of Henle's loop.

  Kidney international 20011101

• Effects of amiloride on gustatory neural responses to salts in the frog.

  Chemical senses 20011101

• Blood pressure responses to small doses of amiloride and spironolactone in normotensive subjects.

  Hypertension (Dallas, Tex. : 1979) 20011101

• Hypoxia reduces alveolar epithelial sodium and fluid transport in rats: reversal by beta-adrenergic agonist treatment.

  American journal of respiratory cell and molecular biology 20011101

• Induction of the epithelial Na+ channel via glucocorticoids in mineralocorticoid receptor knockout mice.

  Pflugers Archiv : European journal of physiology 20011101

• Characterization of the Drosophila melanogaster alkali-metal/proton exchanger (NHE) gene family.

  The Journal of experimental biology 20011101

• Are selective endothelin A receptor antagonists better than mixed antagonists?

  Journal of cardiovascular pharmacology 20011101

• An endogenous Na+, K+-ATPase inhibitor enhances phosphoinositide hydrolysis in neonatal but not in adult rat brain cortex.

  Neurochemical research 20011101

• Inhibition of Na superset+/H superset+ exchange decreases albumin-induced NF-kappaB activation in renal proximal tubular cell lines (OK and LLC-PK1 cells).

  European journal of medical research 20011029

• The effect of leptin on Na(+)-H(+) antiport (NHE 1) activity of obese and normal subjects erythrocytes.

  Molecular and cellular endocrinology 20011025

• Evidence of amiloride-sensitive fluid absorption in rat descending colonic crypts from fluorescence recovery of FITC-labelled dextran after photobleaching.

  The Journal of physiology 20011015

• A spectrophotometric-partial least squares (PLS-1) method for the simultaneous determination of furosemide and amiloride hydrochloride in pharmaceutical formulations.

  Journal of pharmaceutical and biomedical analysis 20011001

• Nongenomic regulation of ENaC by aldosterone.

  American journal of physiology. Cell physiology 20011001

• Acute inhibition of brain-specific Na(+)/H(+) exchanger isoform 5 by protein kinases A and C and cell shrinkage.

  American journal of physiology. Cell physiology 20011001

• Modulation of aldosterone-induced stimulation of ENaC synthesis by changing the rate of apical Na+ entry.

  American journal of physiology. Renal physiology 20011001

• Localization and functional characterization of Na+/H+ exchanger isoform NHE4 in rat thick ascending limbs.

  American journal of physiology. Renal physiology 20011001

• Ion transport by sheep distal airways in a miniature chamber.

  American journal of physiology. Lung cellular and molecular physiology 20011001

• Aldosterone suppresses expression of an avian colonic sodium-glucose cotransporter.

  American journal of physiology. Regulatory, integrative and comparative physiology 20011001

• Role of KCNE1-dependent K+ fluxes in mouse proximal tubule.

  Journal of the American Society of Nephrology : JASN 20011001

• Binding site of amiloride to urokinase plasminogen activator depends on species.

  International journal of molecular medicine 20011001

• Amiloride blocks salt taste transduction of the glossopharyngeal nerve in metamorphosed salamanders.

  Chemical senses 20011001

• Antioxidant compounds and Ca(2+) pathway blockers differentially protect against methylmercury and mercuric chloride neurotoxicity.

  Journal of neuroscience research 20011001

• The methanol hemisolvate of amiloride hydrochloride.

  Acta crystallographica. Section C, Crystal structure communications 20011001

• Phenanthrolines--a new class of CFTR chloride channel openers.

  British journal of pharmacology 20011001

• Amiloride derivatives are potent blockers of KATP channels.

  Naunyn-Schmiedeberg's archives of pharmacology 20011001

• Role of intracellular calcium in the spermicidal action of 2',4'-dichlorobenzamil, a novel contact spermicide.

  The Journal of pharmacy and pharmacology 20011001

• Polyvalent cation-sensing mechanism increased Na(+)-independent Mg(2+) transport in renal epithelial cells.

  Biochemical and biophysical research communications 20010928

• Reduced activity of the NPR-A kinase triggers dephosphorylation and homologous desensitization of the receptor.

  Biochemistry 20010918

• Bicarbonate and fluid secretion evoked by cholecystokinin, bombesin and acetylcholine in isolated guinea-pig pancreatic ducts.

  The Journal of physiology 20010915

• P2Y(2) receptor-mediated inhibition of amiloride-sensitive short circuit current in M-1 mouse cortical collecting duct cells.

  The Journal of membrane biology 20010915

• Mechanism of thiamine uptake by human jejunal brush-border membrane vesicles.

  American journal of physiology. Cell physiology 20010901

• CFTR disruption impairs cAMP-dependent Cl(-) secretion in primary cultures of mouse cortical collecting ducts.

  American journal of physiology. Renal physiology 20010901

• Ammonium interaction with the epithelial sodium channel.

  American journal of physiology. Renal physiology 20010901

• Lack of amiloride-sensitive transport across alveolar and respiratory epithelium of iNOS(-/-) mice in vivo.

  American journal of physiology. Lung cellular and molecular physiology 20010901

• Basolateral translocation by vasopressin of the aldosterone-induced pool of latent Na-K-ATPases is accompanied by alpha1 subunit dephosphorylation: study in a new aldosterone-sensitive rat cortical collecting duct cell line.

  Journal of the American Society of Nephrology : JASN 20010901

• Effects of 8-cpt-cAMP on the epithelial sodium channel expressed in Xenopus oocytes.

  The Journal of membrane biology 20010901

• Transport of (22)Na(+) and( 45)Ca(2+) by Xenopus laevis oocytes expressing mRNA from lobster hepatopancreas.

  The Journal of experimental zoology 20010901

• Effects of various ion transport inhibitors on the water response in the superior laryngeal nerve in rats.

  Chemical senses 20010901

• A modified technique for measurement of nasal transepithelial potential difference in infants.

  The Journal of pediatrics 20010901

• The presence of NHE1 and NHE3 Na+-H+ exchangers and an apical cAMP-independent Cl- channel indicate that both absorptive and secretory functions are present in calf gall bladder epithelium.

  Experimental physiology 20010901

• Differential regulations between adenosine triphosphate (ATP)- and uridine triphosphate-induced Cl(-) secretion in bovine tracheal epithelium. Direct stimulation of P1-like receptor by ATP.

  American journal of respiratory cell and molecular biology 20010901

• Hypoxic activation of an amiloride-sensitive cation conductance in alveolar epithelial cells.

  Biochemical and biophysical research communications 20010824

• Rapid acid extrusion response triggered by alpha(1) adrenoceptor in CHO cells.

  The Journal of physiology 20010815

• Species specificity of amidine-based urokinase inhibitors.

  Biochemistry 20010807

• Na(+)-dependent pH regulation by the amitochondriate protozoan parasite Giardia intestinalis.

  The Journal of biological chemistry 20010803

• ENaC- and CFTR-dependent ion and fluid transport in mammary epithelia.

  American journal of physiology. Cell physiology 20010801

• pH paradox and neonatal heart.

  The Journal of cardiovascular surgery 20010801

• PGE(2) activation of apical membrane Cl(-) channels in A6 epithelia: impedance analysis.

  Biophysical journal 20010801

• Neuronal expression of an FMRFamide-gated Na+ channel and its modulation by acid pH.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010801

• Inhibition of mechanical activation of guinea-pig airway afferent neurons by amiloride analogues.

  British journal of pharmacology 20010801

• Exercise inhibits epithelial sodium channels in patients with cystic fibrosis.

  American journal of respiratory and critical care medicine 20010801

• Endogenous electric current is associated with normal development of the vertebrate limb.

  Developmental dynamics : an official publication of the American Association of Anatomists 20010801

• Characterisation of a human acid-sensing ion channel (hASIC1a) endogenously expressed in HEK293 cells.

  Pflugers Archiv : European journal of physiology 20010801

• Differential roles of the sodium-calcium exchanger in renin secretion and renal vascular resistance.

  Pflugers Archiv : European journal of physiology 20010801

• The disulfonic stilbene DIDS and the marine poison maitotoxin activate the same two types of endogenous cation conductance in the cell membrane of Xenopus laevis oocytes.

  Pflugers Archiv : European journal of physiology 20010801

• The renal Na-HCO3-cotransporter expressed in Xenopus laevis oocytes: inhibition by tenidap and benzamil and effect of temperature on transport rate and stoichiometry.

  Pflugers Archiv : European journal of physiology 20010801

• The effect of cAMP on electrogenic Na(+) absorption in the rat distal colon.

  The Japanese journal of physiology 20010801

• Enhanced epithelial Na(+) channel (ENaC) activity in mouse endometrial epithelium by upregulation of gammaENaC subunit.

  The Japanese journal of physiology 20010801

• Possible involvement of calcium-calmodulin pathways in the positive chronotropic response to angiotensin II on the canine cardiac sympathetic ganglia.

  Japanese journal of pharmacology 20010801

• Characterization of NA+/H+ exchanger isoform (NHE1, NH32 and NHE3) expression in prairie dog gallbladder.

  The Journal of membrane biology 20010715

• Spreading depression in human neocortical slices.

  Brain research 20010706

• Role of Na(+)/H(+) exchanger in dilator responses of rat basilar artery in vivo.

  Brain research 20010706

• Contribution of central amiloride-sensitive transport systems to the development of hypertension in spontaneously hypertensive rats.

  Brain research 20010706

• Biphasic response to human galanin of extracellular acidification in human Bowes melanoma cells.

  European journal of pharmacology 20010706

• Human duodenal mucosal brush border Na(+)/H(+) exchangers NHE2 and NHE3 alter net bicarbonate movement.

  American journal of physiology. Gastrointestinal and liver physiology 20010701

• The effect of amiloride on amphotericin B-induced hypokalaemia.

  The Journal of antimicrobial chemotherapy 20010701

• Molecular basis of ocular abnormalities associated with proximal renal tubular acidosis.

  The Journal of clinical investigation 20010701

• Interaction between store-operated non-selective cation channels and the Na(+)-Ca(2+) exchanger during secretion in the rat colon.

  Experimental physiology 20010701

• The oral sensation of carbonated water: cross-desensitization by capsaicin and potentiation by amiloride.

  Chemical senses 20010701

• Cu2+ reveals amiloride-induced activation and blocking of non-selective cation channel in larval bullfrog skin.

  Pflugers Archiv : European journal of physiology 20010701

• The CF salt controversy: in vivo observations and therapeutic approaches.

  Molecular cell 20010701

• Beta(3)-adrenoceptors control Cl(-) conductance in rabbit nasal epithelium.

  European journal of pharmacology 20010622

• Inhibition of the Na(+)/H(+) antiporter suppresses IL-12 p40 production by mouse macrophages.

  Biochimica et biophysica acta 20010620

• Differential effects of nifedipine and co-amilozide on the progression of early carotid wall changes.

  Circulation 20010619

• Influence of diuretics on the concentration of proteins and other components of pleural transudates in patients with heart failure.

  The American journal of medicine 20010615

• Sodium-coupled glucose transporter as a functional glucose sensor of retinal microvascular circulation.

  Circulation research 20010608

• Bafilomycin A(1) inhibits rhinovirus infection in human airway epithelium: effects on endosome and ICAM-1.

  American journal of physiology. Lung cellular and molecular physiology 20010601

• Mechanisms of TNF-alpha stimulation of amiloride-sensitive sodium transport across alveolar epithelium.

  American journal of physiology. Lung cellular and molecular physiology 20010601

• Acute adaptive cellular base uptake in rat duodenal epithelium.

  American journal of physiology. Gastrointestinal and liver physiology 20010601

• Epithelial Na(+) channels are regulated by flow.

  American journal of physiology. Renal physiology 20010601

• cAMP-dependent fluid secretion in rat inner medullary collecting ducts.

  American journal of physiology. Renal physiology 20010601

• NHE and ICAM-1 expression in hypoxic/reoxygenated coronary microvascular endothelial cells.

  American journal of physiology. Heart and circulatory physiology 20010601

• Activation of epithelial sodium channels by prostasin in Xenopus oocytes.

  Journal of the American Society of Nephrology : JASN 20010601

• Inhibitors of Na(+)/H(+) and Na(+)/Ca(2+) exchange potentiate methamphetamine-induced dopamine neurotoxicity: possible role of ionic dysregulation in methamphetamine neurotoxicity.

  Journal of neurochemistry 20010601

• Type 1 glycogen storage disease and recurrent calcium nephrolithiasis.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010601

• Calcium channel blocker nifedipine slows down progression of coronary calcification in hypertensive patients compared with diuretics.

  Hypertension (Dallas, Tex. : 1979) 20010601

• Adrenergic regulation of ion transport across adult alveolar epithelial cells: effects on Cl- channel activation and transport function in cultures with an apical air interface.

  The Journal of membrane biology 20010601

• Propofol increases myofilament Ca2+ sensitivity and intracellular pH via activation of Na+-H+ exchange in rat ventricular myocytes.

  Anesthesiology 20010601

• pH regulation and buffering power in gastric smooth muscle.

  Pflugers Archiv : European journal of physiology 20010601

• Regulation of cAMP-sensitive colonic epithelial Na+ channel in oocyte expression system.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20010601

• Inhibitory non-genomic effects of progesterone on Na+ absorption in epithelial cells from Xenopus kidney (A6).

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20010601

• Aldosterone upregulates purinergic responses in larval amphibian skin epithelium.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20010601

• Amiloride-sensitive sodium currents in identified taste cells of the frog.

  Neuroreport 20010525

• A standing Na+ conductance in rat carotid body type I cells.

  Neuroreport 20010525

• Dependence of the acid-sensitive ion channel, ASIC1a, on extracellular Ca(2+) ions.

  Brain research 20010511

• Nongenomic effect of testosterone on chloride secretion in cultured rat efferent duct epithelia.

  American journal of physiology. Cell physiology 20010501

• Alveolar epithelial barrier functions in ventilated perfused rabbit lungs.

  American journal of physiology. Lung cellular and molecular physiology 20010501

• Simultaneous direct determination of amiloride and triamterene in urine using isopotential fluorometry.

  Analytical biochemistry 20010501

• Lymph osmolality and rehydration from NaCl solutions by toads, Bufo marinus.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20010501

• Angiotensin II type I receptor modulates intracellular free Mg2+ in renally derived cells via Na+-dependent Ca2+-independent mechanisms.

  The Journal of biological chemistry 20010427

• Roles of the C termini of alpha -, beta -, and gamma -subunits of epithelial Na+ channels (ENaC) in regulating ENaC and mediating its inhibition by cytosolic Na+.

  The Journal of biological chemistry 20010427

• Effect of 2',4'-dichlorobenzamil hydrochloride, a Na(+)-Ca(2+) exchange inhibitor, on human spermatozoa.

  European journal of pharmacology 20010420

• Involvement of noradrenaline transporters in S-nitrosocysteine-stimulated noradrenaline release from rat brain slices: existence of functional Na(+)-independent transporter activity.

  Neurochemistry international 20010401

• Alveolar fluid clearance in late-gestational guinea pigs after labor induction: mechanisms and regulation.

  American journal of physiology. Lung cellular and molecular physiology 20010401

• Roles of ATP and cytoskeleton in the regulation of Na+/H+ exchanger along the nephron luminal membrane.

  Journal of cellular physiology 20010401

• Platelet hyperactivity and abnormal Ca(2+) homeostasis in diabetes mellitus.

  American journal of physiology. Heart and circulatory physiology 20010401

• Characterization of stretch-activated cation current in coronary smooth muscle cells.

  American journal of physiology. Heart and circulatory physiology 20010401

• Contribution of amiloride-insensitive pathways to alveolar fluid clearance in adult rats.

  Journal of applied physiology (Bethesda, Md. : 1985) 20010401

• Effects of SNP, ouabain, and amiloride on electrical potential profile of isolated sheep pleura.

  Journal of applied physiology (Bethesda, Md. : 1985) 20010401

• Regulation of Na(+) transport across leech skin by peptide hormones and neurotransmitters.

  The Journal of experimental biology 20010401

• Oxygen-evoked Na+ transport in rat fetal distal lung epithelial cells.

  The Journal of physiology 20010401

• Maxi K+ channels co-localised with CFTR in the apical membrane of an exocrine gland acinus: possible involvement in secretion.

  Pflugers Archiv : European journal of physiology 20010401

• Caffeine-induced depolarization in amphibian skeletal muscle fibres: role of Na+/Ca2+ exchange and K+ release.

  Acta physiologica Scandinavica 20010401

• HCO3- salvage mechanisms in the submandibular gland acinar and duct cells.

  The Journal of biological chemistry 20010330

• Endothelin-1 has a unique oxygen-saving effect by increasing contractile efficiency in the isolated rat heart.

  Circulation 20010320

• Expression and regulation of normal and polymorphic epithelial sodium channel by human lymphocytes.

  The Journal of biological chemistry 20010316

• Inhibition of Na+-H+ exchanger-3 interferes with apical receptor-mediated endocytosis via vesicle fusion.

  The Journal of physiology 20010315

• L-arginine effects on Na+ transport in M-1 mouse cortical collecting duct cells--a cationic amino acid absorbing epithelium.

  The Journal of membrane biology 20010315

• Serotonin excites tuberomammillary neurons by activation of Na(+)/Ca(2+)-exchange.

  Neuropharmacology 20010301

• Molecular and functional evidence for electrogenic and electroneutral Na(+)-HCO(3)(-) cotransporters in murine duodenum.

  American journal of physiology. Gastrointestinal and liver physiology 20010301

• Characterization of apical membrane Cl-dependent Na/H exchange in crypt cells of rat distal colon.

  American journal of physiology. Gastrointestinal and liver physiology 20010301

• Catecholamines increase lung edema clearance in rats with increased left atrial pressure.

  Journal of applied physiology (Bethesda, Md. : 1985) 20010301

• Collecting duct is a site of sodium retention in PAN nephrosis: a rationale for amiloride therapy.

  Journal of the American Society of Nephrology : JASN 20010301

• Complexities of measuring antagonist potency at P2X(7) receptor orthologs.

  The Journal of pharmacology and experimental therapeutics 20010301

• The use of a response surface methodology on HPLC analysis of methyldopa, amiloride and hydrochlorothiazide in tablets.

  Journal of pharmaceutical and biomedical analysis 20010301

• Gramicidin-perforated patch analysis on HCO3- secretion through a forskolin-activated anion channel in rat parotid intralobular duct cells.

  The Journal of membrane biology 20010301

• The essential role of cytosolic Cl- in Ca2+ regulation of an amiloride-sensitive channel in fetal rat pneumocyte.

  The Journal of membrane biology 20010301

• NaCl detection thresholds: comparison of Fischer 344 and Wistar rats.

  Chemical senses 20010301

• Subtypes of low voltage-activated Ca2+ channels in laterodorsal thalamic neurons: possible localization and physiological roles.

  Pflugers Archiv : European journal of physiology 20010301

• Effects of SM-20550, a selective Na+-H+ exchange inhibitor, on the ion transport of myocardial mitochondria.

  Molecular and cellular biochemistry 20010301

• Sodium channels in the apical membrane of human nasal epithelial cells.

  Chinese medical journal 20010301

• Activation of Na(+), K(+), Cl(-)-cotransport mediates intracellular Ca(2+) increase and apoptosis induced by Pinacidil in HepG2 human hepatoblastoma cells.

  Biochemical and biophysical research communications 20010223

• Ion exchange activity in pulmonary artery smooth muscle cells: the response to hypoxia.

  American journal of physiology. Lung cellular and molecular physiology 20010201

• Expression of multiple Na+/H+ exchanger isoforms in cultured epithelial cells from rat efferent duct and cauda epididymidis.

  Biology of reproduction 20010201

• Inhibition of the NA(+)/H(+) exchanger reduces rat hepatic stellate cell activity and liver fibrosis: an in vitro and in vivo study.

  Gastroenterology 20010201

• Pontine gustatory activity is altered by electrical stimulation in the central nucleus of the amygdala.

  Journal of neurophysiology 20010201

• The binding-site crevice of the D4 dopamine receptor is coupled to three distinct sites of allosteric modulation.

  The Journal of pharmacology and experimental therapeutics 20010201

• Mechanisms of iron transport into rat erythroid cells.

  Journal of cellular physiology 20010201

• Epidermal growth factor regulates the transition from basal sodium absorption to anion secretion in cultured endometrial epithelial cells.

  Journal of cellular physiology 20010201

• Resorptive state and cell size influence intracellular pH regulation in rabbit osteoclasts cultured on collagen-hydroxyapatite films.

  Bone 20010201

• Location and function of the epithelial Na channel in the cochlea.

  American journal of physiology. Renal physiology 20010201

• Protective effect of SM-20550, a selective Na+ - H+ exchange inhibitor, on ischemia-reperfusion-injured hearts.

  Journal of cardiovascular pharmacology 20010201

• Oral irritation by sodium chloride: sensitization, self-desensitization, and cross-sensitization to capsaicin.

  Physiology & behavior 20010201

• Beta1-adrenergic agonist is a potent stimulator of alveolar fluid clearance in hyperoxic rat lungs.

  Japanese journal of pharmacology 20010201

• Location of a ligand recognition site of FMRFamide-gated Na(+) channels.

  FEBS letters 20010126

• Epithelial sodium channel pore region. structure and role in gating.

  The Journal of biological chemistry 20010112

• Tracing the route taken by peptides and major histocompatibility complex class I molecules in presentation of exogenous antigens.

  Methods in molecular biology (Clifton, N.J.) 20010101

• Pharmacological treatment of the ion transport defect in cystic fibrosis.

  Expert opinion on investigational drugs 20010101

• Effect of extracellular Mg(2+) on ROS and Ca(2+) accumulation during reoxygenation of rat cardiomyocytes.

  American journal of physiology. Heart and circulatory physiology 20010101

• Differential transduction mechanisms underlying NaCl- and KCl-induced responses in mouse taste cells.

  Chemical senses 20010101

• Activation of epithelial Na channels during short-term Na deprivation.

  American journal of physiology. Renal physiology 20010101

• Functional role of sodium-calcium exchange in the regulation of renal vascular resistance.

  American journal of physiology. Renal physiology 20010101

• Effects of enzyme and anion transport inhibitors on in vitro incorporation of inorganic carbon and calcium into endolymph and otoliths in salmon Oncorhynchus masou.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20010101

• Interdependence between sodium transport, external chloride, and sodium/calcium exchanger in the isolated skin of the Rana pipiens.

  The Journal of experimental zoology 20010101

• Transport of [3H]MPP+ in an immortalized rat brain microvessel endothelial cell line (RBE 4).

  Naunyn-Schmiedeberg's archives of pharmacology 20010101

• Spermine increases the active and passive transport across the alveolar epithelium in situ: effect of thiol reagents.

  Pflugers Archiv : European journal of physiology 20010101

• Involvement of calcium influx in hypoxia-induced bleb formation in human umbilical vein endothelial cells.

  Transplantation proceedings 20010101

• Impaired sodium excretion, decreased glomerular filtration rate and elevated blood pressure in endothelin receptor type B deficient rats.

  Journal of molecular medicine (Berlin, Germany) 20010101

• Hypertonicity stimulates Cl(-) transport in the intestine of fresh water acclimated eel, Anguilla anguilla.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20010101

• Na+-dependent recovery of intracellular pH from acid loading in mouse colonic crypt cells.

  The Tohoku journal of experimental medicine 20010101

• Response of alkalinization or acidification by phytohemagglutinin is dependent on the activity of protein kinase C in human peripheral T Cells.

  Journal of cellular biochemistry 20010101

• Regulation of tubular cell MCP-1 production by intracellular ions: a role for sodium and calcium.

  Experimental nephrology 20010101

• Inhibition of pig liver and Zea mays L. polyamine oxidase: a comparative study.

  Journal of enzyme inhibition 20010101

• The Na(+)/H(+) exchanger SM-20220 attenuates ischemic injury in in vitro and in vivo models.

  Pharmacology 20010101

• The effect of 5'-(N,N-dimethyl)-amiloride on cytotoxic activity of doxorubicin and vincristine in CEM cell lines.

  Physiological research 20010101

• Effect of linear alkylbenzene sulfonate (LAS) on ion transport and intracellular calcium in kidney distal epithelial cells (A6).

  Toxicology in vitro : an international journal published in association with BIBRA 20010101

• Cell attachment to extracellular matrices is modulated by pulsed radiation at 820 nm and chemicals that modify the activity of enzymes in the plasma membrane.

  Lasers in surgery and medicine 20010101

• Sodium-deprived rat distal colon epithelial response to acute hypoxia and reoxygenation.

  Acta gastroenterologica Latinoamericana 20010101

• Suppression of ATP-induced Cl(-)secretion by enhanced expression of epithelial Na(+)channels in mouse endometrial epithelium.

  Cell biology international 20010101

• Novel inhibitors of the sodium-calcium exchanger: benzene ring analogues of N-guanidino substituted amiloride derivatives.

  European journal of medicinal chemistry 20010101

• The effect of insulin on Na+-H+ antiport activity of obese and normal subjects erythrocytes.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20010101

• A method for measurement of muscarinic receptor-mediated responses in dissociated single colon longitudinal smooth muscle cells.

  Journal of pharmacological and toxicological methods 20010101

• Sodium-calcium exchange in platelets of diabetics.

  Proceedings of the Western Pharmacology Society 20010101

• Inhibition of amiloride-sensitive Na(+) absorption by activation of CFTR in mouse endometrial epithelium.

  Pflugers Archiv : European journal of physiology 20010101

• [Participation of Na/Ca-exchange and intracellular mobilized Ca2+ in regulating depression of cholino-sensitive Helix lucorum neurons to a cellular analog of habituation].

  Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20010101

• [Model experiments of physiologic and pharmacologic interactions with epithelial ionic currents induced by stimulation of sensory receptors ].

  Annales Academiae Medicae Stetinensis 20010101

• Transepithelial resistance can be regulated by the intestinal brush-border Na(+)/H(+) exchanger NHE3.

  American journal of physiology. Cell physiology 20001201

• Estrogen inhibition of cystic fibrosis transmembrane conductance regulator-mediated chloride secretion.

  The Journal of pharmacology and experimental therapeutics 20001001

• Effect of SMP-300, a new Na+/H+ exchange inhibitor, on myocardial ischemia and experimental angina models in rats.

  Japanese journal of pharmacology 20001001

• Heparin-like molecules inhibit pulmonary vascular pericyte proliferation in vitro.

  American journal of physiology. Lung cellular and molecular physiology 20000801

• Influence of ammonia on sodium absorption in rat proximal colon.

  Pflugers Archiv : European journal of physiology 20000801

• Morbidity and mortality in patients randomised to double-blind treatment with a long-acting calcium-channel blocker or diuretic in the International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment (INSIGHT).

  Lancet (London, England) 20000729

• Regulation of human D(1), d(2(long)), d(2(short)), D(3) and D(4) dopamine receptors by amiloride and amiloride analogues.

  British journal of pharmacology 20000701

• Activation of transepithelial ion transport by secretin in human intestinal Caco-2 cells.

  The Japanese journal of physiology 20000401

• Amiloride for the prevention of amphotericin B-induced hypokalemia and hypomagnesemia.

  The Annals of pharmacotherapy 20000101

• Interferon-gamma, bacterial lipopolysaccharide, and tumor necrosis factor-alpha induce CD11a mRNA and protein via Na+/H+ exchange and protein kinase C-dependent mechanisms in tissue macrophages.

  Biochemical and biophysical research communications 19990413

• [The importance of the ion-transport systems of the sarcolemma and sarcoplasmic reticulum in changing rat cardiac contractile function under a hypersodium medium].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 19990401

• Structure and functional characterization of a novel human low-voltage activated calcium channel.

  Journal of neurochemistry 19990201

• Nisoldipine selectively induces coronary vasodilation and improves mild myocardial ischemia in dogs: a potential role of cellular acidosis.

  Cardiovascular drugs and therapy 19981201

• Altered inotropic response of endothelin-1 in cardiomyocytes from rats with isoproterenol-induced cardiomyopathy.

  Cardiovascular research 19980901

• Impact of beta-adrenergic agonist on Na+ channel and Na+-K+-ATPase expression in alveolar type II cells.

  The American journal of physiology 19980801

• Characterization of the allosteric interactions between antagonists and amiloride analogues at the human alpha2A-adrenergic receptor.

  Molecular pharmacology 19980501

• Inhibition of amiloride-sensitive sodium-channel activity in distal lung epithelial cells by nitric oxide.

  The American journal of physiology 19980301

• Reduction in the radiation-induced late S phase and G2 blocks in HL-60 cell populations by amiloride, an efficient inhibitor of the Na+/H+ transporter.

  Cancer research 19980201

• Blood pressure and blood glucose levels during a cross-over treatment of doxazosin, moduretic and amlodipine in hypertensive patients.

  The Kobe journal of medical sciences 19960201

• Granulomatous interstitial nephritis associated with hydrochlorothiazide/amiloride.

  American journal of nephrology 19950101

• The antianginal efficacy of isosorbide dinitrate therapy is maintained during diuretic treatment.

  Clinical pharmacology and therapeutics 19940801

• Diamine oxidase is the amiloride-binding protein and is inhibited by amiloride analogues.

  The Journal of biological chemistry 19940401

• Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits.

  Nature 19940203

• Sodium transport inhibitors decrease proliferation of Pneumocystis carinii in short-term culture.

  The Journal of eukaryotic microbiology 19940101

• Novel amiloride analog allosterically modulates the alpha 2-adrenergic receptor but does not inhibit Na+/H+ exchange.

  Molecular pharmacology 19920801

• Human kidney amiloride-binding protein: cDNA structure and functional expression.

  Proceedings of the National Academy of Sciences of the United States of America 19901001

• Hyponatraemia and Moduretic-grand mal seizures: a review.

  Journal of the Royal Society of Medicine 19890801

• An in vivo study of voltage-dependent renal tubular acidosis induced by amiloride.

  Kidney international 19890501

• [Comparison of the efficacy of monotherapy with a beta-blocker, a diuretic, and ACE inhibitors in the control of blood pressure during stress].

  Minerva cardioangiologica 19890101

• Cardiovascular and renal actions of calcium channel blocker chemical subgroups: a search for renal specificity.

  The Journal of pharmacy and pharmacology 19880601

• Maintenance of potassium balance during long-term diuretic therapy in chronic heart failure patients with thiazide-induced hypokalemia: comparison of potassium supplementation with potassium chloride and potassium-sparing agents, amiloride and triamterene.

  International journal of clinical pharmacology, therapy, and toxicology 19880501

• Amiloride prevents amphotericin B related hypokalaemia in neutropenic patients.

  Journal of clinical pathology 19880501

• Monotherapy with the calcium channel antagonist nisoldipine for systemic hypertension and comparison with diuretic drugs.

  The American journal of cardiology 19870915

• Hydrochlorothiazide with or without amiloride for hypertension in the elderly. A dose-titration study.

  Archives of internal medicine 19870601

• Amiloride selectively inhibits the urokinase-type plasminogen activator.

  FEBS letters 19870406

• Treatment of severe lithium-induced polyuria with amiloride.

  The American journal of psychiatry 19861201

• Hypokalemia in thiazide-treated systemic hypertension.

  The American journal of cardiology 19860731

• Lithium toxicity induced by combined amiloride HCl-hydrochlorothiazide administration.

  The American journal of psychiatry 19860201

• Arrhythmogenic potential of diuretic induced hypokalaemia in patients with mild hypertension and ischaemic heart disease.

  British heart journal 19850901

• Renal failure with potassium-sparing diuretics.

  The New Zealand medical journal 19850814

• Effects of triamterene and amiloride on urinary sediment in hypertensive patients taking hydrochlorothiazide.

  Lancet (London, England) 19850713

• Amiloride in the treatment of lithium-induced diabetes insipidus.

  The New England journal of medicine 19850613

• Amelioration of polyuria by amiloride in patients receiving long-term lithium therapy.

  The New England journal of medicine 19850214

• Antihypertensive treatment using calcium antagonists in combination with captopril rather than diuretics.

  Journal of cardiovascular pharmacology 19850101

• Oral potassium chloride and amiloride in hydrochlorothiazide-induced potassium loss.

  Clinical pharmacology and therapeutics 19841001

• Relationship of renal prostaglandins to three diuretics.

  Prostaglandins, leukotrienes, and medicine 19840601

• Response of thiazide-induced hypokalemia to amiloride.

  JAMA 19830114

• Effects of hydrochlorothiazide combined with amiloride in atenolol-resistant hypertensive patients.

  International journal of clinical pharmacology research 19830101

• Potassium conservation with amiloride/hydrochlorothiazide ('Moduret') in thiazide-induced hypokalaemia in hypertension.

  Current medical research and opinion 19820101

• Antihypertensive, saluretic and hypokalaemic effects of cyclothiazide in comparison with hydrochlorthiazide with amiloride supplement.

  European journal of clinical pharmacology 19820101

• The effect of amiloride/hydrochlorothiazide combination vs furosemide plus potassium supplementation in the treatment of oedema of cardiac origin.

  Annals of clinical research 19810201

• Attenuation of diuretic-induced hypokalemia by amiloride, a potassium-sparing agent.

  Journal of clinical pharmacology 19810101

• Attenuation of the lithium-induced diabetes-insipidus-like syndrome by amiloride in rats.

  Neuropsychobiology 19810101

• Pathophysiology of chronic renal tubular acidosis induced by administration of amiloride.

  The Journal of laboratory and clinical medicine 19800501

• Plasma potassium levels in hypertensive patients receiving fixed-combination diuretic therapy.

  The Medical journal of Australia 19800419

• Amiloride, spironolactone, and potassium chloride in thiazide-treated hypertensive patients.

  Clinical pharmacology and therapeutics 19800401

• Maintenance of potassium balance during diuretic therapy.

  Acta medica Scandinavica 19790101

• The relative potency of amiloride and spironolactone in bendrofluazide-treated hypertensive patients [proceedings].

  British journal of clinical pharmacology 19781101

• Acute effects of lithium on the renal concentrating mechanism in a primate.

  The American journal of physiology 19750301

• Tolerance and side-effects of the association hydrochlorothiazide-amiloride in long-term treatment of arterial hypertension.

  Acta clinica Belgica 19740101