1777-03-3 | (Triethylsilyl)acetylene

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$8.00	$5.00
5g	98%	in stock	$12.00	$9.00
10g	98%	in stock	$14.00	$10.00
25g	98%	in stock	$27.00	$19.00
50g	98%	in stock	$53.00	$37.00
100g	98%	in stock	$98.00	$68.00

Description

• Catalog Number: AB00186
• Chemical Name: (Triethylsilyl)acetylene
• CAS Number: 1777-03-3
• Molecular Formula: C8H16Si
• Molecular Weight: 140.2981
• MDL Number: MFCD00075373
• SMILES: CC[Si](C#C)(CC)CC

Computed Properties

• Complexity: 106
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Rotatable Bond Count: 4

Upstream Synthesis Route

(Triethylsilyl)acetylene is a versatile compound that finds widespread application in organic synthesis. With its unique chemical properties, it serves as a valuable building block in the creation of various complex molecules. In chemical synthesis, (Triethylsilyl)acetylene can be used to introduce the acetylene functionality into organic molecules, allowing for further derivatization and modification. Its compatibility with a wide range of reagents and conditions makes it a valuable tool for organic chemists seeking to construct intricate molecular structures. The presence of the triethylsilyl group provides stability and ease of handling, making (Triethylsilyl)acetylene a preferred choice in synthetic routes that require the introduction of alkynyl groups. The versatility and utility of (Triethylsilyl)acetylene make it an indispensable reagent in modern organic synthesis.

Literature

• Transient and switchable (triethylsilyl)ethynyl protection of DNA against cleavage by restriction endonucleases.

  Angewandte Chemie (International ed. in English) 20110905

• Stereochemical and skeletal diversity arising from amino propargylic alcohols.

  Organic letters 20100618

• Efficient preparation of photoswitchable dithienylethene-linker-conjugates by palladium-catalyzed coupling reactions of terminal alkynes with thienyl chlorides and other aryl halides.

  Chemistry, an Asian journal 20100503

• Total synthesis of (S)-(-)-(E)-15,16-dihydrominquartynoic acid: a highly potent anticancer agent.

  The Journal of organic chemistry 20040514