17833-53-3 | N-Methyl-dl-aspartic acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$14.00	$10.00
1g	98%	in stock	$16.00	$12.00
5g	98%	in stock	$25.00	$17.00
25g	98%	in stock	$49.00	$34.00
100g	98%	in stock	$105.00	$74.00
500g	98%	in stock	$322.00	$225.00

Description

• Catalog Number: AB00822
• Chemical Name: N-Methyl-dl-aspartic acid
• CAS Number: 17833-53-3
• Molecular Formula: C5H9NO4
• Molecular Weight: 147.1293
• MDL Number: MFCD00065918
• SMILES: CN[C@H](C(=O)O)CC(=O)O
• NSC Number: 16206

Computed Properties

• Complexity: 145
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 4
• Undefined Atom Stereocenter Count: 1
• XLogP3: -3.4

Literature

• Chiral separation of N-methyl-DL-aspartic acid in rat brain tissue as N-ethoxycarbonylated (S)-(+)-2-octyl ester derivatives by GC-MS.

  Biomedical chromatography : BMC 20121101

• Enhancement of ON-bipolar cell responses of cone electroretinograms in rabbits with the Pro347Leu rhodopsin mutation.

  Investigative ophthalmology & visual science 20110929

• Vocal babbling in songbirds requires the basal ganglia-recipient motor thalamus but not the basal ganglia.

  Journal of neurophysiology 20110601

• Rhythmic cFos expression in the ventral subparaventricular zone influences general activity rhythms in the Nile grass rat, Arvicanthis niloticus.

  Chronobiology international 20091001

• Seasonal differences of gene expression profiles in song sparrow (Melospiza melodia) hypothalamus in relation to territorial aggression.

  PloS one 20090101

• Anticonvulsant activity of Nylandtia spinosa L. Dumont (Polygalaceae) aqueous and methanol leaf extracts in mice.

  Human & experimental toxicology 20081101

• Photopic ERG negative response from amacrine cell signaling in RCS rat retinal degeneration.

  Investigative ophthalmology & visual science 20080101

• Methods for syntheses of N-methyl-DL-aspartic acid derivatives.

  Amino acids 20071101

• Anticonvulsant activity of Cotyledon orbiculata L. (Crassulaceae) leaf extract in mice.

  Journal of ethnopharmacology 20070530

• The Effect of intravitreal N-methyl-DL-aspartic acid on the electroretinogram in Royal College of surgeons rats.

  Japanese journal of ophthalmology 20070101

• Elevation of intracellular ca(2+) concentration induced by hypoxia in retinal ganglion cells.

  Japanese journal of ophthalmology 20070101

• Morphological evidence that xenon neuroprotects against N-methyl-DL-aspartic acid-induced damage in the rat arcuate nucleus: a time-dependent study.

  Annals of the New York Academy of Sciences 20060801

• Continuous human metastin 45-54 infusion desensitizes G protein-coupled receptor 54-induced gonadotropin-releasing hormone release monitored indirectly in the juvenile male Rhesus monkey (Macaca mulatta): a finding with therapeutic implications.

  Endocrinology 20060501

• Early abnormalities in transgenic mouse models of amyotrophic lateral sclerosis.

  Journal of physiology, Paris 20060101

• Locomotor-like rhythms in a genetically distinct cluster of interneurons in the mammalian spinal cord.

  Journal of neurophysiology 20050301

• Seasonal differences in the secretion of luteinising hormone and prolactin in response to N-methyl-DL-aspartate in starlings (Sturnus vulgaris).

  Journal of neuroendocrinology 20050201

• Altered sensorimotor development in a transgenic mouse model of amyotrophic lateral sclerosis.

  The European journal of neuroscience 20041101

• Reticulospinal neurons receive direct spinobulbar inputs during locomotor activity in lamprey.

  Journal of neurophysiology 20040901

• Effect of glutamate on basal steroidogenesis by ovarian follicles of rainbow trout (Oncorhynchus mykiss).

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20040501

• Neuroprotective and neurotoxic properties of the 'inert' gas, xenon.

  British journal of anaesthesia 20021101

• The respective contribution of lumbar segments to the generation of locomotion in the isolated spinal cord of newborn rat.

  The European journal of neuroscience 20021101

• Effects of xenon on in vitro and in vivo models of neuronal injury.

  Anesthesiology 20020601

• Anticonvulsant activity of aqueous extract of Leonotis leonurus.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20020401

• Variability analyses suggest that supraspino-spinal interactions provide dynamic stability in motor control.

  Brain research 20020315

• Plasma interleukin-1beta, prolactin, ACTH and corticosterone responses to endotoxin after damage of the anterior hypothalamic area.

  Neuroimmunomodulation 20010101

• Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice.

  General pharmacology 19990301