1786-81-8 | Prilocaine, HCl

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$33.00	$23.00
5g	98%	in stock	$65.00	$45.00
25g	98%	in stock	$193.00	$135.00
100g	98%	in stock	$639.00	$447.00

Description

• Catalog Number: AB01117
• Chemical Name: Prilocaine, HCl
• CAS Number: 1786-81-8
• Molecular Formula: C13H21ClN2O
• Molecular Weight: 256.77164
• MDL Number: MFCD00079279
• SMILES: CCCNC(C(=O)Nc1ccccc1C)C.Cl
• NSC Number: 758432

Computed Properties

• Complexity: 218
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 17
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 5
• Undefined Atom Stereocenter Count: 1

Literature

• Comparison of different anaesthetic methodologies for sedation during in vitro fertilization procedures: effects on patient physiology and oocyte competence.

  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20121001

• Topical EMLA for pain control during extracorporeal shock wave lithotripsy: prospective, comparative, randomized, double-blind study.

  Urological research 20121001

• EMLA® cream coated on endotracheal tube with or without epidural lidocaine reduces isoflurane requirement during general anesthesia.

  Frontiers of medicine 20120901

• Effects of temporary functional deafferentation on the brain, sensation, and behavior of stroke patients.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20120822

• Blind or ultrasound-guided corticosteroid injections and short-term response in subacromial impingement syndrome: a randomized, double-blind, prospective study.

  American journal of physical medicine & rehabilitation 20120801

• Impact of the experimental conditions on drug release from parenteral depot systems: From negligible to significant.

  International journal of pharmaceutics 20120801

• Acquired methemoglobinemia due to application of prilocaine during circumcision.

  The Journal of emergency medicine 20120701

• No effect of perianal application of topical anaesthetic on patient comfort during nonsedated flexible sigmoidoscopy: a randomized, placebo-controlled clinical trial.

  Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20120701

• Lichen sclerosus: a 5-year follow-up after topical, subdermal, or combined therapy.

  Journal of lower genital tract disease 20120701

• Pulsed Nd: YAG laser induces pulpal analgesia: a randomized clinical trial.

  Journal of dental research 20120701

• Effects of lidocaine plus epinephrine and prilocaine on autologous fat graft survival.

  The Journal of craniofacial surgery 20120701

• Effects of lidocaine plus epinephrine and prilocaine on autologous fat graft survival.

  The Journal of craniofacial surgery 20120701

• Development of prilocaine gels for enhanced local anesthetic action.

  Archives of pharmacal research 20120701

• Eutectic mixture of local anaesthetics (EMLA) 5% cream as a primary dressing on a painful lower leg ulcer.

  Journal of wound care 20120701

• Combined perianal-intrarectal (PI) lidocaine-prilocaine (LP) cream and lidocaine-ketorolac gel provide better pain relief than combined PI LP cream and periprostatic nerve block during transrectal prostate biopsy.

  BJU international 20120601

• The effect of SonoPrep® on EMLA® cream application for pain relief prior to intravenous cannulation.

  European journal of pediatrics 20120601

• [Circumcision in children: an organizational or an ethical challenge?].

  Annales francaises d'anesthesie et de reanimation 20120501

• Acute central nervous system depression after subcutaneous use of prilocaine in an infant.

  The Journal of emergency medicine 20120401

• A randomized, placebo controlled study: EMLA in minor breast surgery.

  Minerva chirurgica 20120401

• Predictive factors for difficult intravenous cannulation in pediatric patients at a tertiary pediatric hospital.

  Paediatric anaesthesia 20120301

• Methemoglobinemia following prilocaine administration for bilateral tube thoracostomy in a pediatric case.

  Paediatric anaesthesia 20120301

• [Percutaneous mandibular nerve block using neuro-stimulation guiding through the sigmoid indentation in facial surgery].

  Revue de stomatologie et de chirurgie maxillo-faciale 20120201

• Liposomal delivery system for topical anaesthesia of the palatal mucosa.

  The British journal of oral & maxillofacial surgery 20120101

• The alternative ear-piercing technique by using superpulsed carbon dioxide laser: a comparative study with spring-loaded gun.

  European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20120101

• Development of lidocaine-coated microneedle product for rapid, safe, and prolonged local analgesic action.

  Pharmaceutical research 20120101

• [Tolerance and efficacy of peripheral nerve blocks for carpal tunnel release].

  Annales francaises d'anesthesie et de reanimation 20120101

• [Note the irritant effect of Emla® cream potentially leading to diagnostic errors].

  Annales de dermatologie et de venereologie 20120101

• Topical anesthetic (lidocaine-prilocaine) cream application before speculum examination in postmenopausal women.

  Journal of minimally invasive gynecology 20120101

• Evaluation of injection techniques in the treatment of lateral epicondylitis: a prospective randomized clinical trial.

  Acta orthopaedica et traumatologica turcica 20120101

• Assessment of the efficacy of topical anesthetics using the tactile spatial resolution method.

  Acta dermatovenerologica Croatica : ADC 20120101

• Principles of brain plasticity in improving sensorimotor function of the knee and leg in patients with anterior cruciate ligament injury: a double-blind randomized exploratory trial.

  BMC musculoskeletal disorders 20120101

• Effects of midazolam and nitrous oxide on endocrine and metabolic measurements in children.

  Hormone research in paediatrics 20120101

• Videogame playing as distraction technique in course of venipuncture.

  La Pediatria medica e chirurgica : Medical and surgical pediatrics 20120101

• Effect of lidocaine- and prilocaine-based topical anesthetics on the inflammatory exudates in subcutaneous tissue of rats.

  Anesthesia progress 20120101

• Evaluation of EMLA cream for preventing pain during tattooing of rabbits: changes in physiological, behavioural and facial expression responses.

  PloS one 20120101

• Revival of old local anesthetics for spinal anesthesia in ambulatory surgery.

  Current opinion in anaesthesiology 20111201

• Do topical anesthetics reduce periareolar injectional pain before sentinel lymph node biopsy?

  American journal of surgery 20111201

• Analgesia for amniocentesis or chorionic villus sampling.

  The Cochrane database of systematic reviews 20111109

• EMLA versus glucose for PICC insertion: a randomised triple-masked controlled study.

  Archives of disease in childhood. Fetal and neonatal edition 20111101

• Sensory and sympathetic nerve contributions to the cutaneous vasodilator response from a noxious heat stimulus.

  Experimental physiology 20111101

• Dynamic in-situ eutectic formation for topical drug delivery.

  The Journal of pharmacy and pharmacology 20111101

• Tumescent anaesthesia in combination with femoral nerve block for surgery of varicose veins: prilocaine 0.1% versus 0.2%.

  Phlebology 20111001

• [Ulcus curis venosum: topical drugs and dressings in evaluation. How effective are the measures in terms of pain management?].

  Pflege Zeitschrift 20111001

• The effectiveness of Oraqix versus TAC(a) for placement of orthodontic temporary anchorage devices.

  The Angle orthodontist 20110901

• The effect of prilocaine or levobupivacaine infiltration on pain during nasal packing removal.

  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20110901

• Acute bullous irritant contact dermatitis caused by EMLA® cream.

  Contact dermatitis 20110901

• Subacromial corticosteroid injection or acupuncture with home exercises when treating patients with subacromial impingement in primary care--a randomized clinical trial.

  Family practice 20110801

• Impaired transient vasodilation and increased vasoconstriction to digital local cooling in primary Raynaud's phenomenon.

  American journal of physiology. Heart and circulatory physiology 20110801

• Determining the technical and clinical factors associated with pain for children undergoing botulinum toxin injections under nitrous oxide and anesthetic cream.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20110701

• Current therapeutic strategies for premature ejaculation and future perspectives.

  Asian journal of andrology 20110701

• Analgesic effects of EMLA cream and oral sucrose during venipuncture in preterm infants.

  Pediatrics 20110701

• Dimethyl sulfoxide with lignocaine versus eutectic mixture of local anesthetics: prospective randomized study to compare the efficacy of cutaneous anesthesia in shock wave lithotripsy.

  Urological research 20110601

• Prilocaine-cyclodextrin-liposome: effect of pH variations on the encapsulation and topology of a ternary complex using 1H NMR.

  Magnetic resonance in chemistry : MRC 20110601

• Severe adverse reactions to dental local anaesthetics: systemic reactions.

  Australian dental journal 20110601

• Comparison of the efficacy of articaine and prilocaine local anaesthesia for pulpotomy of maxillary and mandibular primary molars.

  European journal of paediatric dentistry : official journal of European Academy of Paediatric Dentistry 20110601

• [Ventricular fibrillation with tolonium chloride: axillary brachial plexus anesthesia led to cessation of circulation].

  Der Anaesthesist 20110501

• Trigeminal nerve injury associated with injection of local anesthetics: needle lesion or neurotoxicity?

  Journal of the American Dental Association (1939) 20110501

• [Toxic methemoglobinemia].

  Deutsche medizinische Wochenschrift (1946) 20110401

• Clinical inquiries. What's the best way to control circumcision pain in newborns?

  The Journal of family practice 20110401

• Topical anesthetic EMLA for postoperative wound pain in stereotactic gamma knife radiosurgery: a perspective, randomized, placebo-controlled study.

  Minimally invasive neurosurgery : MIN 20110401

• Care to relieve pain-stress in preterm newborns.

  Acta bio-medica : Atenei Parmensis 20110401

• Use of a diode laser in an excisional biopsy of two spoonlike neoformations on the tongue tip.

  Acta bio-medica : Atenei Parmensis 20110401

• Anesthetic efficacy of liposomal prilocaine in maxillary infiltration anesthesia.

  Journal of liposome research 20110301

• The link between penile hypersensitivity and premature ejaculation.

  BJU international 20110201

• Management of pain associated with debridement of leg ulcers: a randomized, multicentre, pilot study comparing nitrous oxide-oxygen mixture inhalation and lidocaïne-prilocaïne cream.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20110201

• Effect of eutectic mixture of local anesthetics on pain perception during scaling by ultrasonic or hand instruments: a masked randomized controlled trial.

  Journal of periodontology 20110201

• Spinal anaesthesia for ambulatory arthroscopic surgery of the knee: a comparison of low-dose prilocaine and fentanyl with bupivacaine and fentanyl.

  British journal of anaesthesia 20110201

• Use of a temporary forearm tourniquet for intravenous regional anaesthesia: a randomised controlled trial.

  European journal of anaesthesiology 20110201

• Meatotomy using local anesthesia and sedation or general anesthesia with or without penile block in children: a prospective randomized study.

  The Journal of urology 20110201

• Update on treatments for premature ejaculation.

  International journal of clinical practice 20110101

• Reducing procedural pain and discomfort associated with transcranial direct current stimulation.

  Brain stimulation 20110101

• [Campaign against pain in pediatrics, nurses are mobilized].

  Soins. Pediatrie, puericulture 20110101

• [Acute cyanosis after transcatheter balloon valvuloplasty: toxic methemoglobinemia due to local prilocaine use].

  Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir 20110101

• [Anaesthetic effect of acupuncture during an inguinal hernia repair – a self-experiment].

  Forschende Komplementarmedizin (2006) 20110101

• [The surface anesthesia in outpatient pediatric department].

  Khirurgiia 20110101

• Drug fever caused by eutectic mixture of local anesthetic cream.

  Journal of investigational allergology & clinical immunology 20110101

• Inadvertent brachial plexus anesthesia associated with local anesthetic infiltration during internal jugular venous cannulation: a case report.

  Acta anaesthesiologica Belgica 20110101

• Vapocoolant spray vs lidocaine/prilocaine cream for reducing the pain of venipuncture in hemodialysis patients: a randomized, placebo-controlled, crossover study.

  International journal of medical sciences 20110101

• Effectiveness of lumbar zygapophysial joint blockage for low back pain.

  Turkish neurosurgery 20110101

• Liposomal formulations of prilocaine: effect of complexation with hydroxypropyl-ß-cyclodextrin on drug anesthetic efficacy.

  Journal of liposome research 20101201

• Influence of high dose tumescent local anaesthesia with prilocaine on systemic interleukin (IL)-6, IL-8 and tumour necrosis factor-α.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20101201

• Pain reduction in children during port-à-cath catheter puncture using local anaesthesia with EMLA™.

  European journal of pediatrics 20101201

• Comparative pharmacokinetic assessments of topical drugs: evaluation by dermatopharmacokinetics, microdialysis, and systemic measurement.

  The Journal of investigative dermatology 20101201

• Severe methemoglobinemia after dental anesthesia: a warning about propitocaine-induced methemoglobinemia in neonates.

  Journal of anesthesia 20101201

• The effectiveness of local anesthetics in preventing postoperative adhesions in rat models.

  Techniques in coloproctology 20101201

• Anesthesia for ritual circumcision in neonates.

  Paediatric anaesthesia 20101201

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Oral paresthesia.

  Journal of the American Dental Association (1939) 20101101

• Bring on the heat: transient receptor potential vanilloid type-1 (TRPV-1) channels as a sensory link for local thermal hyperaemia.

  The Journal of physiology 20101101

• Trigeminal nerve injuries in relation to the local anaesthesia in mandibular injections.

  British dental journal 20101101

• Pulse-oximetric measurement of prilocaine-induced methemoglobinemia in regional anesthesia.

  Anesthesia and analgesia 20101001

• Local anesthetics: pharmacology and toxicity.

  Dental clinics of North America 20101001

• Acquired methemoglobinemia revisited.

  Dental clinics of North America 20101001

• Paresthesias in dentistry.

  Dental clinics of North America 20101001

• EMLA patch for myringotomy and ventilation tube insertion in the outpatient clinic.

  Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery 20101001

• Visual pain score during transrectal ultrasound-guided prostate biopsy using no anaesthesia or three different types of local anaesthetic application.

  Scandinavian journal of urology and nephrology 20100901

• Improved ejaculatory latency, control and sexual satisfaction when PSD502 is applied topically in men with premature ejaculation: results of a phase III, double-blind, placebo-controlled study.

  The journal of sexual medicine 20100901

• Regional intravenous anesthesia in knee arthroscopy.

  Clinics (Sao Paulo, Brazil) 20100901

• A prospective, double-blinded, randomized, clinical trial comparing the efficacy of 40 mg and 60 mg hyperbaric 2% prilocaine versus 60 mg plain 2% prilocaine for intrathecal anesthesia in ambulatory surgery.

  Anesthesia and analgesia 20100801

• Comparative evaluation of topical and electronic anesthesia during scaling and root planing.

  Journal of periodontology 20100701

• Occurrence of paresthesia after dental local anesthetic administration in the United States.

  Journal of the American Dental Association (1939) 20100701

• Safety of lidocaine 15% and prilocaine 5% topical ointment used as local anesthesia for intense pulsed light treatment.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20100701

• Available and future therapies for premature ejaculation.

  Drugs of today (Barcelona, Spain : 1998) 20100701

• A fundamental investigation into the effects of eutectic formation on transmembrane transport.

  International journal of pharmaceutics 20100630

• Toxic methemoglobinemia due to prilocaine use.

  The Journal of emergency medicine 20100601

• [Topical anesthesia before vascular access in children. Comparison of a warmth-producing lidocaine-tetracaine patch with a lidocaine-prilocaine patch].

  Der Anaesthesist 20100601

• Use of topical as only anesthetic for suturing a traumatic facial laceration.

  Dental traumatology : official publication of International Association for Dental Traumatology 20100601

• Do local anesthetics have antibacterial effect on Staphylococcus aureus under in vivo conditions? An experimental study.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20100601

• Methemoglobinemia due to local anesthesia with prilocaine for circumcision.

  Journal of paediatrics and child health 20100601

• Coarse grained simulations of local anesthetics encapsulated into a liposome.

  The journal of physical chemistry. B 20100527

• Felypressin, but not epinephrine, reduces myocardial oxygen tension after an injection of dental local anesthetic solution at routine doses.

  Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20100501

• Urinary retention after spinal anaesthesia with hyperbaric prilocaine 2% in an ambulatory setting.

  British journal of anaesthesia 20100501

• Prilocain-induced methemoglobinemia after endovenous laser ablation.

  Journal of vascular and interventional radiology : JVIR 20100501

• Usage of lidocaine-prilocaine cream in the treatment of postburn pain in pediatric patients.

  Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES 20100501

• Topical agents or dressings for pain in venous leg ulcers.

  The Cochrane database of systematic reviews 20100414

• Comparison of local anesthetic effects of tramadol with prilocaine during circumcision procedure.

  Urology 20100301

• A comfortable and practical nasal packing method: tied Merocel in clear glove finger impregnated with lidocaine-prilocaine cream.

  Plastic and reconstructive surgery 20100301

• Editorial comment.

  Urology 20100301

• Safe and less painful injection of triamcenolone acetonide into a keloid--a technique.

  Journal of plastic, reconstructive & aesthetic surgery : JPRAS 20100201

• Premature ejaculation: treatment update.

  International journal of STD & AIDS 20100201

• Randomized study of the effect of topical anesthesia on tuberculin skin test reaction size in children.

  The Pediatric infectious disease journal 20100201

• The effect of a new topical local anaesthetic delivery system on forearm skin blood flow reactivity.

  Anaesthesia 20100201

• Local anesthetics structure-dependently interact with anionic phospholipid membranes to modify the fluidity.

  Chemico-biological interactions 20100105

• Thyroid fine needle aspiration biopsy: is topical local anaesthesia beneficial?

  International journal of clinical practice 20100101

• The efficacy of a topical anesthetic gel in the relief of pain associated with localized alveolar osteitis.

  Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20100101

• A prospective, randomized, double-blind comparison of 2% lidocaine with 1:100,000 epinephrine, 4% prilocaine with 1:200,000 epinephrine, and 4% prilocaine for maxillary infiltrations.

  Anesthesia progress 20100101

• Methemoglobinemia and local anesthesia: what every dentist should know.

  Journal of the Massachusetts Dental Society 20100101

• Comparison of hemodynamic effects of lidocaine, prilocaine and mepivacaine solutions without vasoconstrictor in hypertensive patients.

  Journal of applied oral science : revista FOB 20100101

• Double-blind, randomized, intraindividual comparison study of the efficacy of prilocaine and lidocaine in tumescent local anesthesia.

  Dermatology (Basel, Switzerland) 20100101

• ECG variations in patients pre- and post-local anaesthesia and analgesia.

  British dental journal 20091219

• Effectiveness of nitrous oxide and analgesic cream (lidocaine and prilocaine) for prevention of pain during intramuscular botulinum toxin injections in children.

  Annals of physical and rehabilitation medicine 20091201

• Complex regional pain syndrome type I: efficacy of stellate ganglion blockade.

  Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology 20091201

• Pharmacokinetics and clinical toxicity of prilocaine and ropivacaine following combined drug administration in brachial plexus anesthesia.

  International journal of clinical pharmacology and therapeutics 20091201

• Adverse events associated with intravenous regional anesthesia (Bier block): a systematic review of complications.

  Journal of clinical anesthesia 20091201

• Aspirations and solutions--a 20 year journey through dental local anaesthetics.

  The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland 20091201

• Combined use of infraorbital and external nasal nerve blocks for effective perioperative pain control during and after cleft lip repair.

  The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 20091101

• Survey of local anesthetic use by Ontario dentists.

  Journal (Canadian Dental Association) 20091101

• Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

  Nature chemical biology 20091001

• Retrospective review of voluntary reports of nonsurgical paresthesia in dentistry.

  Journal (Canadian Dental Association) 20091001

• Lidocaine-based topical anesthetic with disinfectant (LidoDin) versus EMLA for venipuncture: a randomized controlled trial.

  The Clinical journal of pain 20091001

• [Radial nerve block for implantation of radial catheter].

  Annales francaises d'anesthesie et de reanimation 20090901

• Sexual dysfunction: anesthetic spray improves premature ejaculation.

  Nature reviews. Urology 20090901

• Viability of preadipocytes in vitro: the influence of local anesthetics and pH.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20090801

• Contact dermatitis to prilocaine after tumescent anesthesia.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20090801

• Comparison between lidocaine-prilocaine cream (EMLA) and mepivacaine infiltration for pain relief during perineal repair after childbirth: a randomized trial.

  American journal of obstetrics and gynecology 20090801

• The efficacy of six local anesthetic formulations used for posterior mandibular buccal infiltration anesthesia.

  Journal of the American Dental Association (1939) 20090801

• A clinical comparison of topical piroxicam and EMLA cream for pain relief and inflammation in laser hair removal.

  Lasers in medical science 20090701

• Influence of topical anaesthesia on the corticomotor response to tongue training.

  Archives of oral biology 20090701

• Amethocaine versus EMLA for successful intravenous cannulation in a children's emergency department: a randomised controlled study.

  Emergency medicine journal : EMJ 20090701

• [Pain therapy using stimulating catheters after total knee arthroplasty].

  Schmerz (Berlin, Germany) 20090601

• The influence of a eutectic mixture of lidocaine and prilocaine on minor surgical procedures: a randomized controlled double-blind trial.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20090601

• [Premature ejaculation].

  Der Urologe. Ausg. A 20090601

• Sex effects on life span and senescence in the wild when dates of birth and death are unknown.

  Ecology 20090601

• Pregnancy at term does not alter the responses to a mechanical and an electrical stimulus after skin EMLA application.

  Middle East journal of anaesthesiology 20090601

• Stimulated skin wrinkling for predicting intraepidermal nerve fibre density.

  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20090501

• The effect of different vasoconstrictors and local anesthetic solutions on substance P expression in human dental pulp.

  Journal of endodontics 20090501

• Spinal myoclonus following intrathecal anaesthesia with prilocaine.

  Anaesthesia and intensive care 20090501

• [Methemoglobin intoxication by prilocaine in EMLA. Accidental intoxication of an infant with scald injuries].

  Der Anaesthesist 20090401

• PSD502 improves ejaculatory latency, control and sexual satisfaction when applied topically 5 min before intercourse in men with premature ejaculation: results of a phase III, multicentre, double-blind, placebo-controlled study.

  BJU international 20090401

• Interventions to reduce pain during vaccination in infancy.

  The Journal of pediatrics 20090301

• Allergic contact dermatitis from EMLA cream: concomitant sensitization to both local anesthetics lidocaine and prilocaine.

  Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20090301

• Differential effects of skin nerves on allergic skin inflammation.

  Allergy 20090301

• Methemoglobinemia related to local anesthetics: a summary of 242 episodes.

  Anesthesia and analgesia 20090301

• Petechial and purpuric eruption induced by lidocaine/prilocaine cream: a rare side effect.

  Journal of drugs in dermatology : JDD 20090301

• Liposome-prilocaine interaction mapping evaluated through STD NMR and molecular dynamics simulations.

  The journal of physical chemistry. B 20090226

• Ultrasound-guided ulnar nerve catheter placement in the forearm for postoperative pain relief and physiotherapy.

  Acta anaesthesiologica Scandinavica 20090201

• Combination of perianal-intrarectal lidocaine-prilocaine cream and periprostatic nerve block for pain control during transrectal ultrasound guided prostate biopsy: a randomized, controlled trial.

  The Journal of urology 20090201

• Plain articaine or prilocaine for spinal anaesthesia in day-case knee arthroscopy: a double-blind randomized trial.

  British journal of anaesthesia 20090201

• Heated lidocaine/tetracaine patch (Synera, Rapydan) compared with lidocaine/prilocaine cream (EMLA) for topical anaesthesia before vascular access.

  British journal of anaesthesia 20090201

• A comparison of the antimicrobial property of lidocaine/prilocaine cream (EMLA) and an alcohol-based disinfectant on intact human skin flora.

  Anesthesia and analgesia 20090201

• Second-degree skin burn after intense pulsed light therapy with EMLA cream for hair removal.

  International journal of dermatology 20090201

• Hypnosis as an alternative to avoid general anesthesia in a child with severe pulmonary arterial hypertension.

  Paediatric anaesthesia 20090201

• Rapid cortical reorganisation and improved sensitivity of the hand following cutaneous anaesthesia of the forearm.

  The European journal of neuroscience 20090201

• [Suspected allergy to local anesthetics prior to dental treatment].

  Lakartidningen 20090201

• Improved sensibility of the foot after temporary cutaneous anesthesia of the lower leg.

  Neuroreport 20090107

• Orgasmic headache responsive to greater occipital nerve blockade.

  Headache 20090101

• Assessment of genotoxicity of Lidocaine, Prilonest and Septanest in the Drosophila wing-spot test.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090101

• Methemoglobinemia due to local anesthesia with low-dose prilocaine.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20090101

• EMLA Cream coated on the rigid bronchoscope for tracheobronchial foreign body removal in children.

  The Laryngoscope 20090101

• Addition of dexmedetomidine or lornoxicam to prilocaine in intravenous regional anaesthesia for hand or forearm surgery: a randomized controlled study.

  Clinical drug investigation 20090101

• The challenge of sedation with adolescents: case studies and clinical recommendations.

  SAAD digest 20090101

• A comparison between EMLA cream application versus lidocaine infiltration for postoperative analgesia after inguinal herniotomy in children.

  Regional anesthesia and pain medicine 20090101

• [Topical anesthetics: are these products harmless to one's health?].

  Perspective infirmiere : revue officielle de l'Ordre des infirmieres et infirmiers du Quebec 20090101

• A single-surgeon, single-institute experience of 115 Lichtenstein hernia repairs under local anesthesia.

  Bratislavske lekarske listy 20090101

• Is only perianal anesthesia with lidocaine-prilocaine cream sufficient to decrease the pain during transrectal ultrasound-guided prostate biopsy? A prospective randomized study.

  Urologia internationalis 20090101

• Comparison of three analgesic treatment protocols for pain management during extracorporeal shock wave lithotripsy.

  Urologia internationalis 20090101

• [Simultaneous determination of prilocaine and lidocaine in transdermal receiving fluid using gas chromatography-mass spectrometry].

  Se pu = Chinese journal of chromatography 20090101

• Spinal procaine is less neurotoxic than mepivacaine, prilocaine and bupivacaine in rats.

  Regional anesthesia and pain medicine 20090101

• Principles of brain plasticity in improving sensorimotor function of the knee and leg in healthy subjects: a double-blind randomized exploratory trial.

  BMC musculoskeletal disorders 20090101

• Comparison of two different anesthesia techniques for tourniquet pain with the use of forearm tourniquet.

  The Iowa orthopaedic journal 20090101

• EMLA cream for carpal tunnel syndrome: how it compares with steroid injection.

  Electromyography and clinical neurophysiology 20090101

• Topical anesthesia for rubber dam clamp placement in sealant placement: comparison of lidocaine/prilocaine gel and benzocaine.

  Pediatric dentistry 20090101

• Change of skin color after application of topical anesthetic cream.

  The Journal of dermatological treatment 20090101

• Atraumatic care: EMLA cream and application of heat to facilitate peripheral venous cannulation in children.

  Issues in comprehensive pediatric nursing 20090101

• An investigation into the influence of binary drug solutions upon diffusion and partition processes in model membranes.

  The Journal of pharmacy and pharmacology 20081201

• Methemoglobinemia due to application of prilocaine during circumcision and the effect of ascorbic acid.

  Journal of pediatric urology 20081201

• Is spinal anesthesia not enough for major abdominal procedures of neonates?

  Paediatric anaesthesia 20081201

• A fixed drug eruption that developed cross-sensitivity among amide local anaesthetics, including mepivacaine hydrochloride, lidocaine hydrochloride and propitocaine hydrochloride.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20081101

• A prospective randomised controlled trial to investigate the effect of local anaesthetic in vivo on cell culture.

  Journal of plastic, reconstructive & aesthetic surgery : JPRAS 20081001

• Evaluation of dressings used with local anaesthetic cream and for peripheral venous cannulation.

  Paediatric nursing 20081001

• Transient hyperaemic response to assess vascular reactivity of skin: effect of topical anaesthesia.

  British journal of anaesthesia 20080901

• Effect of local anesthetics with and without vasoconstrictor agent in patients with ventricular arrhythmias.

  Arquivos brasileiros de cardiologia 20080901

• Assessment of the medicines lidocaine, prilocaine, and their metabolites, 2,6-dimethylaniline and 2-methylaniline, for DNA adduct formation in rat tissues.

  Drug metabolism and disposition: the biological fate of chemicals 20080801

• The FLACC behavioral scale for procedural pain assessment in children aged 5-16 years.

  Paediatric anaesthesia 20080801

• Optimizing local anesthesia for grommet insertion: eutectic mixture of local anaesthetics versus Ametop: a randomized clinical trial.

  Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20080801

• Relieving the pain of sentinel lymph node biopsy tracer injection.

  Clinical journal of oncology nursing 20080801

• Reversal of soft-tissue local anesthesia with phentolamine mesylate in adolescents and adults.

  Journal of the American Dental Association (1939) 20080801

• Low risk of postinflammatory hyperpigmentation in skin types 4 and 5 after treatment with fractional CO2 laser device.

  Journal of drugs in dermatology : JDD 20080801

• Allergic contact dermatitis to all three classes of local anaesthetic.

  Contact dermatitis 20080801

• [Methemoglobinemia induced by local anesthetic administration previous to laser depilation].

  Medicina clinica 20080705

• Leg ulcer progression caused by topical anesthesia with EMLA cream.

  Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20080701

• Mechanisms of pain referral in patients with whiplash-associated disorder.

  European journal of pain (London, England) 20080701

• Application of topical analgesia in triage: a potential for harm.

  The Journal of emergency medicine 20080701

• Topical anesthesia with EMLA does not decrease pain during vasectomy.

  The Journal of urology 20080701

• A comparison of injection pain with articaine with adrenaline, prilocaine with phenylpressin and lidocaine with adrenaline.

  Medicina oral, patologia oral y cirugia bucal 20080701

• [Tissue augmentation with hyaluronic acid fillers--practical procedure].

  Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20080701

• Abnormal digital neurovascular response to local heating in systemic sclerosis.

  Rheumatology (Oxford, England) 20080601

• EMLA cream and nitrous oxide to alleviate pain induced by palivizumab (Synagis) intramuscular injections in infants and young children.

  Pediatrics 20080601

• Topical anesthetic creams.

  Plastic and reconstructive surgery 20080601

• Groin flap immobilization by axillary brachial plexus block anesthesia.

  Techniques in hand & upper extremity surgery 20080601

• Methemoglobin levels during epidural anesthesia for renal transplantation--comparison of prilocaine with bupivacaine.

  Middle East journal of anaesthesiology 20080601

• Editorial comment on: topical prilocaine-lidocaine cream combined with peripheral nerve block improves pain control in prostatic biopsy: results from a prospective randomized trial.

  European urology 20080501

• Editorial comment on: topical prilocaine-lidocaine cream combined with peripheral nerve block improves pain control in prostatic biopsy: results from a prospective randomized trial.

  European urology 20080501

• Topical prilocaine-lidocaine cream combined with peripheral nerve block improves pain control in prostatic biopsy: results from a prospective randomized trial.

  European urology 20080501

• Local anesthesia with 20-mL prilocaine infiltration: the ultimate point for analgesia during shockwave lithotripsy?

  Journal of endourology 20080501

• The effects of general anesthesia on the central nervous and cardiovascular system toxicity of local anesthetics.

  Anesthesia and analgesia 20080501

• The effects of general anesthesia on whole body and regional pharmacokinetics of local anesthetics at toxic doses.

  Anesthesia and analgesia 20080501

• Lidocaine increases intracellular sodium concentration through a Na+-H+ exchanger in an identified Lymnaea neuron.

  Anesthesia and analgesia 20080501

• Reversal of central nervous system and cardiac toxicity after local anesthetic intoxication by lipid emulsion injection.

  Anesthesia and analgesia 20080501

• Recovery of nerve injury-induced alexia for Braille using forearm anaesthesia.

  Neuroreport 20080416

• Topical anaesthesia and intravenous cannulation success in paediatric patients: a randomized double-blind trial.

  British journal of anaesthesia 20080401

• It's been a long time coming, but that's good.

  BJU international 20080401

• EMLA cream application without occlusive dressing before upper facial botulinum toxin injection: a randomized, double-blind, placebo-controlled trial.

  Annals of plastic surgery 20080401

• Local anesthetic cream prepared from lidocaine-tetracaine eutectic mixture.

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080401

• Antimicrobials in periodontics: controlling chronic disease.

  Dentistry today 20080401

• The effect of 50% glycolic acid on the percutaneous absorption of eutectic mixture of local anesthetics (EMLA): a study of the electrofulguration-induced pain.

  International journal of dermatology 20080301

• Clinical inquiries. What's the best drug treatment for premature ejaculation?

  The Journal of family practice 20080301

• Ulceration of gingival mucosa after topical application of EMLA: report of four cases.

  British dental journal 20080209

• Treatment of molluscum contagiosum with a pulsed dye laser: Pilot study with 19 children.

  Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20080201

• Healing pattern of experimental soft tissue lacerations after application of novel topical anesthetic agents - an experimental study in rabbits.

  Dental traumatology : official publication of International Association for Dental Traumatology 20080201

• Galactography without discomfort using lidocaine/prilocaine anesthetic cream.

  Acta radiologica (Stockholm, Sweden : 1987) 20080201

• TEMPE: Topical Eutectic-Like Mixture for Premature Ejaculation.

  Expert opinion on drug delivery 20080201

• Molecular interactions in lipophilic environments studied by electrochemistry at interfaces between immiscible electrolyte solutions.

  Analytical chemistry 20080101

• Analysis of the antimicrobial activity of local anaesthetics used for dental analgesia.

  Journal of medical microbiology 20080101

• Premature ejaculation: current and future treatments.

  Asian journal of andrology 20080101

• Use of a topical anesthetic cream (EMLA) to reduce pain after hemorrhoidectomy.

  Regional anesthesia and pain medicine 20080101

• Patient comfort in regional anesthesia.

  Anesthesia and analgesia 20080101

• Improved hand function in a dental hygienist with neuropathy induced by vibration and compression: the effect of cutaneous anaesthetic treatment of the forearm.

  Scandinavian journal of plastic and reconstructive surgery and hand surgery 20080101

• Clonidine as an adjuvant to intrathecal local anesthetics for surgery: systematic review of randomized trials.

  Regional anesthesia and pain medicine 20080101

• Patch-test reactions to topical anesthetics: retrospective analysis of cross-sectional data, 2001 to 2004.

  Dermatitis : contact, atopic, occupational, drug 20080101

• Usefulness of noninjectable anesthetic gel for intraperiodontal gingival retraction.

  The International journal of prosthodontics 20080101

• [Purpura after application of a eutectic mixture of local anesthetic].

  Actas dermo-sifiliograficas 20080101

• Severe allergic reactions to prilocaine during intravenous regional anesthesia.

  European journal of dermatology : EJD 20080101

• In vitro antibacterial effects of topical local anesthetics.

  The Journal of dermatological treatment 20080101

• Reducing pain from palatal needle stick by topical anesthetics: a comparative study between two lidocaine/prilocaine substances.

  The Journal of clinical dentistry 20080101

• Stability and local toxicity evaluation of a liposomal prilocaine formulation.

  Journal of liposome research 20080101

• Intraperitoneal EMLA (lidocaine/prilocaine) to prevent abdominal adhesion formation in a rat peritonitis model.

  Bratislavske lekarske listy 20080101

• EMLA and water immersion cause similar vasodilatation in replanted fingers.

  The Journal of surgical research 20071201

• Comparison of sciatic psoas compartment block and sciatic femoral 3-in-1 block for knee arthroscopy.

  Journal of clinical anesthesia 20071201

• The effect of prilocaine and prilocaine plus meperidine infiltration on the pain during nasal packing removal.

  Rhinology 20071201

• Prilocaine induced methaemoglobinaemia in a medically compromised patient. Was this an inevitable consequence of the dose administered?

  British dental journal 20071124

• Human cutaneous reactive hyperaemia: role of BKCa channels and sensory nerves.

  The Journal of physiology 20071115

• The standard of care for nonsurgical periodontal treatment for reducing the dental risk for cardiac disease.

  Dentistry today 20071101

• Development and validation of gas chromatography-mass spectroscopy method for determination of prilocaine HCl in human plasma using internal standard methodology.

  Biomedical chromatography : BMC 20071001

• Severe needle phobia in the perianesthesia setting.

  Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses 20071001

• Comparative evaluation of myolaxin and EMLA cream for attenuation of venous cannulation pain: a prospective, randomised, double blind study.

  Anaesthesia and intensive care 20071001

• The efficacy of lidocaine-prilocaine cream to reduce pain in genetic amniocentesis.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20071001

• Combination of topical EMLA with local injection of lidocaine: superior pain relief after Ferguson hemorrhoidectomy.

  The Clinical journal of pain 20070901

• Routine immunization practices: use of topical anesthetics and oral analgesics.

  Pediatrics 20070901

• [Tumescent anaesthesia for dermatological surgery. Plasma concentrations of lidocaine and prilocaine].

  Der Anaesthesist 20070801

• Eutectic mixture of local anesthetic (EMLA) decreases pain during humeral block placement in nonsedated patients.

  Anesthesia and analgesia 20070801

• The endoscopic application of eutetic mixture of local anaesthetics cream.

  Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery 20070801

• Histologic cutaneous modifications after the use of EMLA cream, a diagnostic pitfall: review of 13 cases.

  Archives of dermatology 20070801

• Frequency of transient ipsilateral vocal cord paralysis in patients undergoing carotid endarterectomy under local anesthesia.

  Journal of vascular surgery 20070701

• Regional anesthetic techniques are an alternative to general anesthesia for infants with Pompe's disease.

  Paediatric anaesthesia 20070701

• Potential mechanisms by which a single drink of alcohol can increase transdermal absorption of topically applied chemicals.

  Toxicology 20070625

• Preoperative application of EMLA cream and the temporomandibular arthrocentesis procedure.

  The British journal of oral & maxillofacial surgery 20070601

• [Evaluation of analgesic protocol with nitrous oxide and EMLA cream during botulinum toxin injections in children].

  Annales de readaptation et de medecine physique : revue scientifique de la Societe francaise de reeducation fonctionnelle de readaptation et de medecine physique 20070601

• Obturator nerve block and transurethral surgery for bladder cancer.

  Minerva urologica e nefrologica = The Italian journal of urology and nephrology 20070601

• [The influence of different local anaesthetics on the viability of preadipocytes].

  Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... 20070601

• Reducing the pain during children's immunizations.

  Child health alert 20070601

• Pre- versus postoperative intraarticular application of local anesthetics and opioids versus femoral nerve block in anterior cruciate ligament repair.

  Archives of orthopaedic and trauma surgery 20070501

• Lidocaine-prilocaine (EMLA) cream as analgesia for hysterosalpingography: a prospective, randomized, controlled, double blinded study.

  Human reproduction (Oxford, England) 20070501

• The pH changes of calcium hydroxide mixed with six different vehicles.

  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20070501

• Comparison of topical anesthetics (EMLA/Oraqix vs. benzocaine) on pain experienced during palatal needle injection.

  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20070501

• The analgesic efficacy of lidocaine/prilocaine (EMLA) cream during fine-needle aspiration biopsy of thyroid nodules.

  Clinical endocrinology 20070501

• [Spinal anaesthesia in day-case surgery. Optimisation of procedures].

  Der Anaesthesist 20070401

• Posterior vitrectomy under topical anesthesia.

  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20070401

• Percutaneous penetration kinetics of lidocaine and prilocaine in two local anesthetic formulations assessed by in vivo microdialysis in pigs.

  Biological & pharmaceutical bulletin 20070401

• Comparing two local anesthesia techniques for extracorporeal shock wave lithotripsy.

  Urology 20070401

• Injection of the subacromial-subdeltoid bursa: blind or ultrasound-guided?

  Acta orthopaedica 20070401

• Effects of local anaesthesia on subdermal needle insertion pain and subsequent tests of microvascular function in human.

  European journal of pharmacology 20070322

• Transdermal diclofenac patch vs eutectic mixture of local anesthetics for venous cannulation pain.

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 20070301

• Lidocaine alters the input resistance and evokes neural activity in crayfish sensory neurons.

  General physiology and biophysics 20070301

• Predictors of topical anesthetic effectiveness in children.

  The journal of pain : official journal of the American Pain Society 20070201

• Topical eutectic mixture for premature ejaculation (TEMPE): a novel aerosol-delivery form of lidocaine-prilocaine for treating premature ejaculation.

  BJU international 20070201

• A study of regional nerve blocks and local anesthetic creams (Prilox) for donor sites in burn patients.

  Burns : journal of the International Society for Burn Injuries 20070201

• Methemoglobinemia after low-dose prilocaine in an adult patient receiving barbiturate comedication.

  Anesthesia and analgesia 20070201

• Contact dermatitis from prilocaine with cross-sensitivity to pramocaine and bupivacaine.

  Contact dermatitis 20070201

• Hemoglobin adducts of the human bladder carcinogen o-toluidine after treatment with the local anesthetic prilocaine.

  Toxicology 20070105

• The anaesthetist sandwich.

  International journal of obstetric anesthesia 20070101

• The effect of a eutectic mixture of local anesthetic cream on wrist pain during transradial coronary procedures.

  The Journal of invasive cardiology 20070101

• Cardiovascular collapse developing after topical anesthesia.

  Dermatology (Basel, Switzerland) 20070101

• Providing pain relief for laser resurfacing: effectiveness of the CoolAnalgesia device.

  Journal of plastic, reconstructive & aesthetic surgery : JPRAS 20070101

• Efficacy of skin cooling and EMLA cream application for pain relief of periocular botulinum toxin injection.

  Ophthalmic plastic and reconstructive surgery 20070101

• Altered blood flow in terminal vessels after local application of ropivacaine and prilocaine.

  Regional anesthesia and pain medicine 20070101

• Efficacy of 1% ropivacaine gel for topical anesthesia of human oral mucosa.

  Quintessence international (Berlin, Germany : 1985) 20070101

• Reversal of prilocaine epidural anesthesia using epidural saline or ringer's lactate washout.

  Regional anesthesia and pain medicine 20070101

• Enhanced sensory relearning after nerve repair by using repeated forearm anaesthesia: aspects on time dynamics of treatment.

  Acta neurochirurgica. Supplement 20070101

• Effect of eutectic mixture of local anesthetics (EMLA) for pain relief during suprapubic aspiration in young infants: a randomized, controlled trial.

  The Clinical journal of pain 20070101

• [Sensory injury to the lingual nerve after nerve block at the lingula mandibulae].

  Revue belge de medecine dentaire 20070101

• Use of lidocaine-prilocaine patch for the mantoux test: Influence on pain and reading.

  International journal of pharmaceutics 20061211

• [Coma in a child after treatment with the 'magic salve' lidocaine-prilocaine cream].

  Nederlands tijdschrift voor geneeskunde 20061209

• [Coma in a child after treatment with the 'magic salve' lidocaine-prilocaine cream].

  Nederlands tijdschrift voor geneeskunde 20061209

• [Coma in a child after treatment with the 'magic salve' lidocaine-prilocaine cream].

  Nederlands tijdschrift voor geneeskunde 20061209

• [Use of ways to prevent pain].

  Soins. Pediatrie, puericulture 20061201

• Liposomal formulations of prilocaine, lidocaine and mepivacaine prolong analgesic duration.

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 20061101

• Abdominal pain related to mitochondrial neurogastrointestinal encephalomyopathy syndrome may benefit from splanchnic nerve blockade.

  Paediatric anaesthesia 20061001

• Risk factors for prilocaine-induced methaemoglobinaemia following peripheral regional anaesthesia.

  European journal of anaesthesiology 20060901

• Topical anesthesia with EMLA reduces pain during endomyocardial biopsy: a randomized trial.

  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060901

• [Coma in a child after treatment with the 'magic salve' lidocaine-prilocaine cream].

  Nederlands tijdschrift voor geneeskunde 20060819

• Efficacy of EMLA cream to reduce fear and pain associated with interferon beta-1a injection in patients with multiple sclerosis.

  The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses 20060801

• Safe and effective carbon dioxide laser skin resurfacing of the neck.

  Lasers in surgery and medicine 20060801

• EMLA and amethocaine for reduction of children's pain associated with needle insertion.

  The Cochrane database of systematic reviews 20060719

• Efficacy of intraoral topical anesthetics in children.

  Journal of dentistry 20060701

• Can prilocaine infiltration alone be the most minimally invasive approach in terms of anesthesia during extracorporeal shock wave lithotripsy?

  Urology 20060701

• Lidocaine-prilocaine administration during transrectal ultrasound-guided prostatic biopsy: a randomized, single-blind, placebo-controlled trial.

  Journal of endourology 20060701

• Does amethocaine gel influence blood results obtained from capillary sampling?

  Paediatric nursing 20060701

• The 'inverted cup' -- a novel in vitro release technique for drugs in lipid formulations.

  Journal of controlled release : official journal of the Controlled Release Society 20060612

• Comparative study of different concentrations of prilocaine and ropivacaine for intraoperative axillary brachial plexus block.

  European journal of anaesthesiology 20060601

• [Painful defecation and chronic functional constipation in children: Diagnosis and treatment].

  Minerva pediatrica 20060601

• Allergic contact dermatitis from EMLA cream in a hemodialyzed patient.

  Dermatitis : contact, atopic, occupational, drug 20060601

• Nerve injury caused by mandibular block analgesia.

  International journal of oral and maxillofacial surgery 20060501

• Comparison of ropivacaine 2 mg ml(-1) and prilocaine 5 mg ml(-1) for i.v. regional anaesthesia in outpatient surgery.

  British journal of anaesthesia 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Nicolau's syndrome in a newborn caused by triple DTP (diphtheria-tetanus-pertussis) vaccination.

  Journal of the American Academy of Dermatology 20060501

• Pain- and distress-reducing interventions for venepuncture in children.

  Child: care, health and development 20060501

• Perianal and intrarectal anaesthesia for transrectal biopsy of the prostate: a prospective randomized study comparing lidocaine-prilocaine cream and placebo.

  BJU international 20060501

• Method development for the enantiomeric purity determination of low concentrations of adrenaline in local anaesthetic solutions by capillary electrophoresis.

  Journal of pharmaceutical and biomedical analysis 20060411

• [Acute pain management in proximal femoral fractures: femoral nerve block (catheter technique) vs. systemic pain therapy using a clinic internal organisation model].

  Der Anaesthesist 20060401

• Improved sensory relearning after nerve repair induced by selective temporary anaesthesia - a new concept in hand rehabilitation.

  Journal of hand surgery (Edinburgh, Scotland) 20060401

• Adverse effects of EMLA (lidocaine/prilocaine) cream and efficacy for the placement of jugular catheters in hospitalized cats.

  Journal of feline medicine and surgery 20060401

• [Avoiding and dealing with bleeding during endoscopic sinus surgery].

  Laryngo- rhino- otologie 20060401

• Quantitative impurity profiling by principal component analysis of high-performance liquid chromatography-diode array detection data.

  Journal of chromatography. A 20060303

• Photocontact allergy to oxybenzone and contact allergy to lignocaine and prilocaine.

  Contact dermatitis 20060301

• Palmar hyperhidrosis. Safety efficacy of two anaesthetic techniques for botulinum toxin therapy.

  Dermatology online journal 20060227

• A video study of pain relief during newborn male circumcision.

  Journal of perinatology : official journal of the California Perinatal Association 20060201

• A comparison of a needle-free injection system for local anesthesia versus EMLA for intravenous catheter insertion in the pediatric patient.

  Anesthesia and analgesia 20060201

• Comparison of efficacy of sildenafil-only, sildenafil plus topical EMLA cream, and topical EMLA-cream-only in treatment of premature ejaculation.

  Urology 20060201

• A randomized, double-blind comparison of two topical anesthetic formulations prior to electrodesiccation of dermatosis papulosa nigra.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20060101

• Ultralong peripheral nerve block by lidocaine:prilocaine 1:1 mixture in a lipid depot formulation: comparison of in vitro, in vivo, and effect kinetics.

  Anesthesiology 20060101

• Functional connectivity between trigeminal and occipital nerves revealed by occipital nerve blockade and nociceptive blink reflexes.

  Cephalalgia : an international journal of headache 20060101

• Randomized, double-blind, placebo-controlled prospective study of the efficacy of topical anaesthesia with a eutetic mixture of lignocaine 2.5% and prilocaine 2.5% for topical 5-aminolaevulinic acid-photodynamic therapy for extensive scalp actinic keratoses.

  The British journal of dermatology 20060101

• Prilocaine induced methemoglobinemia.

  Saudi medical journal 20060101

• A convenient TLC method for the identification of local anesthetics.

  Die Pharmazie 20060101

• Magnesium added to prilocaine prolongs the duration of axillary plexus block.

  Regional anesthesia and pain medicine 20060101

• The effect of local anaesthetic cream (EMLA) applied with an occlusive dressing on skin thickness. Does it matter?

  Journal of plastic, reconstructive & aesthetic surgery : JPRAS 20060101

• Injection pain of prilocaine plain, mepivacaine plain, articaine with epinephrine, and lidocaine with epinephrine.

  General dentistry 20060101

• Comparison of injection modalities in the treatment of plantar heel pain: a randomized controlled trial.

  Journal of the American Podiatric Medical Association 20060101

• Antibacterial properties of EMLA and lidocaine in wound tissue biopsies for culturing.

  Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20060101

• Methemoglobinemia and CNS toxicity after topical application of EMLA to a 4-year-old girl with molluscum contagiosum.

  Pediatric dermatology 20060101

• Evaluation of three topical anaesthetic agents against pain: a clinical study.

  Indian journal of dental research : official publication of Indian Society for Dental Research 20060101

• Transdermal anaesthesia for percutaneous trigger finger release.

  Hand surgery : an international journal devoted to hand and upper limb surgery and related research : journal of the Asia-Pacific Federation of Societies for Surgery of the Hand 20060101

• A survey of local anaesthetic use among general dental practitioners in the UK attending postgraduate courses on pain control.

  British dental journal 20051224

• Perianal and intrarectal anaesthesia for transrectal biopsy of the prostate: a prospective randomized study comparing lidocaine-prilocaine cream and placebo.

  BJU international 20051201

• Alkalinisation of local anaesthetics prescribed for pain relief after surgical decompression of carpal tunnel syndrome.

  Journal of orthopaedic surgery (Hong Kong) 20051201

• Nitrous oxide inhalation is a safe and effective way to facilitate procedures in paediatric outpatient departments.

  Archives of disease in childhood 20051001

• Topical anesthetics for dermal instrumentation: a systematic review of randomized, controlled trials.

  Annals of emergency medicine 20051001

• Topical EMLA cream versus prilocaine infiltration for pediatric cardiac catheterization.

  Journal of cardiothoracic and vascular anesthesia 20051001

• Estimation of pK(a) values using microchip capillary electrophoresis and indirect fluorescence detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050925

• Simultaneous determination of bupivacaine, mepivacain, prilocaine and ropivacain in human serum by liquid chromatography-tandem mass spectrometry.

  Journal of chromatography. A 20050923

• Greater occipital nerve block is ineffective in chronic tension type headache.

  Cephalalgia : an international journal of headache 20050901

• [Comparison of clonidine and tramadol added to prilocaine brachial plexus block - analgesia, sensory and motor block].

  Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 20050901

• [Application of EMLA creme before upper lid blepharoplasty].

  Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20050801

• [Probable methemoglobinemia following EMLA administration].

  Anales de pediatria (Barcelona, Spain : 2003) 20050801

• Best evidence topic report. Fasting before prilocaine Biers' block.

  Emergency medicine journal : EMJ 20050801

• [Obturator nerve block for transurethral surgery. comparing ropivacaine 0.75 % vs. prilocaine 1 %].

  Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 20050701

• Lidocaine 4% cream compared with lidocaine 2.5% and prilocaine 2.5% or dorsal penile block for circumcision.

  American journal of perinatology 20050701

• A double-blind, randomized, placebo-controlled trial of prilocaine and felypressin (Citanest and Octapressin) for the relief of pain associated with cervical biopsy and treatment with the Semm coagulator.

  Journal of lower genital tract disease 20050701

• Use of a eutectic mixture of lidocaine 2.5% and prilocaine 2.5% as a local anesthetic in animals.

  Journal of the American Veterinary Medical Association 20050615

• Comparison of topical lidocaine/prilocaine anesthetic cream and local infiltration of 2% lidocaine for episioplasty in mares.

  Journal of veterinary pharmacology and therapeutics 20050601

• Effectiveness of eutectic mixture of local anesthetic cream and occlusive dressing with low dosage of fentanyl for pain control during shockwave lithotripsy.

  Journal of endourology 20050601

• Current trends in local anesthesia in cosmetic plastic surgery of the head and neck: results of a German national survey and observations on the use of ropivacaine.

  Plastic and reconstructive surgery 20050501

• Phimosis. Preputial plasty using transversal widening on the dorsal side with EMLA local anesthetic cream.

  Journal of pediatric surgery 20050401

• Vascular access.

  Nephrology news & issues 20050401

• Direct comparison of EMLA versus lidocaine for pain control in Nd:YAG 1,064 nm laser hair removal.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20050401

• Which local anesthesia should be used in neonatal circumcision in newborns?

  Saudi medical journal 20050401

• Permanent vision loss in one eye following administration of local anesthesia for a dental extraction.

  International journal of oral and maxillofacial surgery 20050301

• Comparison of the effects of nebulised and inhaled salbutamol on breathlessness in severe COPD.

  Respiratory medicine 20050301

• Enhancement of dorsal random-pattern skin flap survival in rats with topical lidocaine and prilocaine (EMLA): enhancement of flap survival by EMLA.

  The Journal of surgical research 20050301

• Takayasu's arteritis: what should the dentist know?

  International journal of paediatric dentistry 20050301

• Intravenous ketamine sedation for painful oncology procedures.

  Paediatric anaesthesia 20050201

• Iatrogenic swollen penis.

  Sexually transmitted infections 20050201

• Emla cream-induced allergic contact dermatitis in a child with thalassaemia major.

  Contact dermatitis 20050201

• Local anaesthesia--after xylocaine.

  Anaesthesia and intensive care 20050201

• The need for pain control during scaling and root planing.

  Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995) 20050201

• Efficacy of an intrapocket anesthetic for scaling and root planing procedures: a review of three multicenter studies.

  Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995) 20050201

• [Optimized use of Emla cream in children--secondary publication. A randomized, prospective, controlled comparison of two application regimes].

  Ugeskrift for laeger 20050124

• Using EMLA cream before venipuncture.

  Nursing 20050101

• EMLA for painful procedures in infants.

  Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners 20050101

• Local approaches to the pain of pressure ulcers.

  Ostomy/wound management 20050101

• [Emla, the cream].

  Revue de l'infirmiere 20050101

• Bupivacaine versus lidocaine analgesia for neonatal circumcision.

  BMC pediatrics 20050101

• Local anesthesia in transrectal ultrasound-guided prostate biopsy: EMLA cream as a new alternative technique.

  Scandinavian journal of urology and nephrology 20050101

• Differences between men and women regarding attitudes toward dental local anesthesia among junior students at a United Kingdom dental school.

  Anesthesia progress 20050101

• Midazolam premedication in children: a pilot study comparing intramuscular and intranasal administration.

  Anesthesia progress 20050101

• Reduction of pain from needle stick in the oral mucosa by topical anesthetics: a comparative study between lidocaine/prilocaine and benzocaine.

  The Journal of clinical dentistry 20050101

• Do topical analgesics reduce pain associated with wound dressing changes or debridement of chronic wounds?

  Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society 20050101

• Purpura after application of EMLA cream in two children.

  Pediatric dermatology 20050101

• Effectiveness of fixed 50% nitrous oxide oxygen mixture and EMLA cream for insertion of central venous catheters in children.

  Pediatric blood & cancer 20041201

• No effect of skin anesthesia on pain intensity ratings associated with elicitation of the H-reflex in the soleus muscle.

  The International journal of neuroscience 20041201

• A randomized, double-blind comparison study of EMLA and ELA-Max for topical anesthesia in children undergoing intravenous insertion.

  Paediatric anaesthesia 20041201

• Retrobulbar hemorrhage after sub-Tenon's anesthesia.

  Journal of cataract and refractive surgery 20041201

• New drugs for local anesthesia and oral sedation.

  Dentistry today 20041201

• [2/6 EMLA cream application].

  Soins. Pediatrie, puericulture 20041201

• Quantification and analysis of pain in nonsurgical scaling and/or root planing.

  Journal of the American Dental Association (1939) 20041201

• Managing orthodontic pain.

  Journal of clinical orthodontics : JCO 20041201

• Pudendal nerve block for pain relief in episiotomy repair.

  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20041101

• Relief of pain and anxiety in pediatric patients in emergency medical systems.

  Pediatrics 20041101

• Acute improvement of hand sensibility after selective ipsilateral cutaneous forearm anaesthesia.

  The European journal of neuroscience 20041101

• Central nervous system toxicity following topical skin application of lidocaine.

  European journal of clinical pharmacology 20041101

• Prilocaine or mepivacaine for combined sciatic-femoral nerve block in patients receiving elective knee arthroscopy.

  Minerva anestesiologica 20041101

• Pain relief for neonatal circumcision.

  The Cochrane database of systematic reviews 20041018

• Pain during transrectal ultrasonography guided prostate biopsy: a randomized prospective trial comparing periprostatic infiltration with lidocaine with the intrarectal instillation of lidocaine-prilocain cream.

  World journal of urology 20041001

• The efficacy of LMX versus EMLA for pain relief in boys undergoing office meatotomy.

  The Journal of urology 20041001

• [Predicting the use of Emla cream by the triage nurse in a paediatric emergency department].

  Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20041001

• Results of intravenous regional anaesthesia with distal forearm application.

  Acta orthopaedica Belgica 20041001

• Anesthetic implications of Leigh's syndrome.

  Paediatric anaesthesia 20040901

• Unilateral pudendal nerve blockade for relief of all pain during transrectal ultrasound-guided biopsy of the prostate: a randomized, double-blind, placebo-controlled study.

  Urology 20040901

• Recent developments in local anesthesia and oral sedation.

  Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995) 20040901

• Lidocaine iontophoresis versus EMLA cream for CO2 laser treatment in seborrheic keratosis.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20040901

• [Analgesic effects of Emla cream and saccharose solution for subcutaneous injections in preterm newborns: a prospective study of 265 injections].

  Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20040801

• Use of topical application of lidocaine-prilocaine cream to reduce injection-site pain of depot antipsychotics.

  Psychiatric services (Washington, D.C.) 20040801

• Liposomal prilocaine: preparation, characterization, and in vivo evaluation.

  Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20040715

• Re: Bier's block using prilocaine: safe, cheap and well tolerated. Surg J R Coll Edinb Irel 2003; 1(5):283-5.

  The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland 20040601

• Re: Bier 's block using prilocaine: safe, cheap and well tolerated. Surg J R Coll Edinb Irel 2003; 1: 283-285.

  The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland 20040601

• Topical anaesthetic use for treating premature ejaculation: a double-blind, randomized, placebo-controlled study.

  BJU international 20040501

• Improved application of Lidocaine/Prilocaine cream in children. A randomized and prospectively controlled study of two application regimes.

  Acta anaesthesiologica Scandinavica 20040401

• A prospective study of pain following loop excision of the transformation zone under local anaesthesia.

  Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20040401

• Study on the efficacy of ELA-Max (4% liposomal lidocaine) compared with EMLA cream (eutectic mixture of local anesthetics) using thermosensory threshold analysis in adult volunteers.

  The Journal of dermatological treatment 20040401

• Topical anaesthesia in neonates, infants and children.

  British journal of anaesthesia 20040301

• EMLA and ear surgery: is it possible to achieve full-thickness anesthesia with EMLA?

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20040301

• Role of histamine release in nonspecific vasodilatation during anodal and cathodal iontophoresis.

  Microvascular research 20040301

• Immunological modulation by lidocaine-epinephrine and prilocaine-felypressin on the functions related to natural immunity in neutrophils and macrophages.

  Current drug targets. Immune, endocrine and metabolic disorders 20040301

• Comparison of EMLA and lidocaine iontophoresis for cannulation analgesia.

  European journal of anaesthesiology 20040301

• Does lidocaine-prilocaine cream (EMLA) decrease the pain of neonatal circumcision?

  American family physician 20040215

• Rapid onset of cutaneous anesthesia with EMLA cream after pretreatment with a new ultrasound-emitting device.

  Anesthesia and analgesia 20040201

• EMLA toxicity after application for allergy skin testing.

  Pediatrics 20040201

• Intrathecal morphine vs psoas compartment block for hip surgery.

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 20040201

• The use of EMLA cream to decrease venipuncture pain in children.

  Journal of pediatric nursing 20040201

• A microdialysis model to examine nasal drug delivery and olfactory absorption in rats using lidocaine hydrochloride as a model drug.

  International journal of pharmaceutics 20040128

• Loco-regional anaesthesia for a total knee arthroplasty in a high-risk cardiac patient.

  Acta anaesthesiologica Scandinavica 20040101

• Lidocaine/prilocaine cream (EMLA) has an antibacterial effect in vitro.

  The Journal of hospital infection 20040101

• EMLA-induced methemoglobinemia and systemic topical anesthetic toxicity.

  The Journal of emergency medicine 20040101

• Diffusion of Ca(OH)2 associated with different vehicles: chromatographic study (high-performance liquid chromatography).

  Journal of endodontics 20040101

• Effect of cutaneously applied nonionic surfactants and local anesthetic bases on thermal sensations.

  Die Pharmazie 20040101

• Anesthesia technique for outpatient facial laser resurfacing.

  Lasers in surgery and medicine 20040101

• Implant surgery for a patient with Parkinson's disease controlled by intravenous midazolam: a case report.

  The International journal of oral & maxillofacial implants 20040101

• ESWL: Comparing two analgesic techniques. Our experience.

  Urologia internationalis 20040101

• 60-minute application of S-Caine Peel prior to 1,064 nm long-pulsed Nd:YAG laser treatment of leg veins.

  Lasers in surgery and medicine 20040101

• Pseudo-lysosomal storage disease caused by EMLA cream.

  Journal of inherited metabolic disease 20040101

• Delayed-type hypersensitivity to amide local anesthetics.

  Allergologia et immunopathologia 20040101

• Intrathecal mepivacaine and prilocaine are less neurotoxic than lidocaine in a rat intrathecal model.

  Regional anesthesia and pain medicine 20040101

• [Effectiveness of interscalene plexus block for open subacromion decompression].

  Zeitschrift fur Orthopadie und ihre Grenzgebiete 20040101

• Pain management for newborn circumcision.

  Pediatric nursing 20040101

• Contact urticaria from Emla cream.

  Contact dermatitis 20040101

• EMLA cream is an effective topical anesthetic for bronchoscopy.

  Canadian respiratory journal 20040101

• Outpatient hysteroscopy: an observational study of patient acceptability.

  Medicina (Kaunas, Lithuania) 20040101

• The wand versus traditional injection for mandibular nerve block in children and adolescents: perceived pain and time of onset.

  Pediatric dentistry 20040101

• Evaluating the efficacy of EMLA topical anesthetic in sealant placement with rubber dam.

  Pediatric dentistry 20040101

• Filter paper cards contaminated with EMLA cream produce artefacts on acylcarnitine analysis.

  Journal of inherited metabolic disease 20040101

• Prilocaine plasma levels and methemoglobinemia in patients undergoing tumescent liposuction involving less than 2,000 ml.

  Aesthetic plastic surgery 20040101

• Prilocaine versus plain or buffered lidocaine for local anesthesia in laceration repair: randomized double-blind comparison.

  Croatian medical journal 20031201

• Ca2+ diffusion through dentin of Ca(OH)2 associated with seven different vehicles.

  Journal of endodontics 20031201

• Combination of adenosine with prilocaine and lignocaine for brachial plexus block does not prolong postoperative analgesia.

  Anaesthesia and intensive care 20031201

• Evaluation of adverse effects of EMLA (lidocaine/prilocaine) cream for the placement of jugular catheters in healthy cats.

  Journal of veterinary pharmacology and therapeutics 20031201

• Effects of a topical anesthetic on non-socially maintained self-injurious behavior.

  Developmental medicine and child neurology 20031101

• A randomized trial of eutectic mixture of local anesthetics during lumbar puncture in newborns.

  Archives of pediatrics & adolescent medicine 20031101

• [Methemoglobinemia due to prilocaine after plexus anesthesia. Reduction by prophylactic administration of ascorbic acid?].

  Der Anaesthesist 20031101

• Effects of the prilocaine and of the association of prilocaine with different vasoconstrictors on the isolated hearts of rats.

  Pharmacological research 20031001

• Statistical process control methods allow the analysis and improvement of anesthesia care.

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 20031001

• Piroxicam gel, compared to EMLA cream is associated with less pain after venous cannulation in volunteers.

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 20031001

• Kinetics of degradation of 4-imidazolidinone prodrug types obtained from reacting prilocaine with formaldehyde and acetaldehyde.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20031001

• Full-face laser resurfacing using a supplemented topical anesthesia protocol.

  Archives of dermatology 20031001

• Bier's block using prilocaine: safe, cheap and well tolerated.

  The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland 20031001

• The efficacy of 5% lidocaine-prilocaine (EMLA) cream on pain during intravenous injection of propofol.

  Anesthesia and analgesia 20030901

• Sharp wound debridement in local anaesthesia using EMLA cream: 6 years' experience in 1084 patients.

  European journal of emergency medicine : official journal of the European Society for Emergency Medicine 20030901

• Perceptual integration of intramuscular electrical stimulation in the focal and the referred pain area in healthy humans.

  Pain 20030901

• [No problem with liposuction?].

  Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 20030901

• Comment on 'Four analgesic techniques for shockwave lithotripsy: eutectic mixture local anesthetic is a good alternative'.

  Journal of endourology 20030901

• Can acupuncture reduce the induction time of a local anaesthetic?--A pilot study.

  Acupuncture in medicine : journal of the British Medical Acupuncture Society 20030901

• Effects of local injection of prilocaine-felypressin on the myocardial oxygen balance in dogs.

  European journal of oral sciences 20030801

• Topical lidocaine-prilocaine spray for the treatment of premature ejaculation: a proof of concept study.

  International journal of impotence research 20030801

• Plasma levels of lidocaine, o-toluidine, and prilocaine after application of 8.5 g Oraqix in patients with generalized periodontitis: effect on blood methemoglobin and tolerability.

  Acta odontologica Scandinavica 20030801

• [Cutaneous permeation kinetics and pharmacodynamics of topical lidocaine gel in rat].

  Yao xue xue bao = Acta pharmaceutica Sinica 20030801

• EMLA does not permit pain-free retrobulbar injection.

  Acta anaesthesiologica Scandinavica 20030701

• Water immersion and EMLA cause similar digit skin wrinkling and vasoconstriction.

  Microvascular research 20030701

• Does using heat with eutectic mixture of local anesthetic cream shorten analgesic onset time? A randomized, placebo-controlled trial.

  Annals of emergency medicine 20030701

• EMLA cream and oral glucose for immunization pain in 3-month-old infants.

  Pain 20030701

• Influence of local anaesthetics on inflammatory activity postburn.

  Burns : journal of the International Society for Burn Injuries 20030601

• Pain management in nursing procedures on premature babies.

  Journal of advanced nursing 20030601

• Topical local anesthetics.

  The American journal of nursing 20030601

• Microemulsions as colloidal vehicle systems for dermal drug delivery. Part IV: Investigation of microemulsion systems based on a eutectic mixture of lidocaine and prilocaine as the colloidal phase by dynamic light scattering.

  The Journal of pharmacy and pharmacology 20030601

• Urethral meatal dilatation using topical EMLA cream for anaesthesia.

  Paediatric anaesthesia 20030501

• Minimum clinically significant VAS differences for simultaneous (paired) interval serial pain assessments.

  The American journal of emergency medicine 20030501

• Intrapocket anesthesia for scaling and root planing in pain-sensitive patients.

  Journal of periodontology 20030501

• Comparison of local anaesthetic effects of tramadol with prilocaine for minor surgical procedures.

  British journal of anaesthesia 20030301

• Evaluation of eutectic lidocaine/prilocaine cream (EMLA) for steroid joint injection in children with juvenile rheumatoid arthritis: a double blind, randomized, placebo controlled trial.

  The Journal of rheumatology 20030301

• A placebo-controlled multi-centred evaluation of an anaesthetic gel (Oraqix) for periodontal therapy.

  Journal of clinical periodontology 20030301

• Effective reduction of anxiety and pain during venous cannulation in children: a comparison of analgesic efficacy conferred by nitrous oxide, EMLA and combination.

  Paediatric anaesthesia 20030301

• EMLA cream versus dorsal penile nerve block for postcircumcision analgesia in children.

  Anesthesia and analgesia 20030201

• Four analgesic techniques for shockwave lithotripsy: eutectic mixture local anesthetic is a good alternative.

  Journal of endourology 20030201

• A review of paresthesia in association with administration of local anesthesia.

  Dentistry today 20030201

• Mechanisms contributing to the vaso-active effects of prilocaine in human skin.

  Anaesthesia 20030101

• Pain and distress from bone marrow aspirations and lumbar punctures.

  The Annals of pharmacotherapy 20030101

• Double-blind, randomized, placebo-controlled trial to determine the efficacy of eutectic lidocaine/prilocaine (EMLA) cream for decreasing pain during local anaesthetic infiltration for out-patient haemorrhoidectomy.

  Asian journal of surgery 20030101

• Topical agents or dressings for pain in venous leg ulcers.

  The Cochrane database of systematic reviews 20030101

• Anaesthetic and haemodynamic effects of continuous spinal versus continuous epidural anaesthesia with prilocaine.

  European journal of anaesthesiology 20030101

• Important drug interactions and reactions in dermatology.

  Dermatologic clinics 20030101

• The relationship of application time to EMLA efficacy.

  Journal of dentistry for children (Chicago, Ill.) 20030101

• The influence of Emla cream on cutaneous microcirculation.

  Clinical hemorheology and microcirculation 20030101

• Pain reduction at venipuncture in newborns: oral glucose compared with local anesthetic cream.

  Pediatrics 20021201

• Optimum usage of prilocaine-lidocaine cream in premature ejaculation.

  Andrologia 20021201

• [Spinal anesthesia: articaine, prilocaine, lidocaine?].

  Der Anaesthesist 20021201

• Injection pain of bupivacaine with epinephrine vs. prilocaine plain.

  Journal of the American Dental Association (1939) 20021201

• Recurrent facial swelling following dental procedures.

  The Medical journal of Australia 20021104

• The effect of guanethidine and local anesthetics on the electrically stimulated mouse vas deferens.

  Anesthesia and analgesia 20021101

• Intravenous regional anesthesia using prilocaine and neostigmine.

  Anesthesia and analgesia 20021101

• Safety in numbers: how do we study toxicity of spinal analgesics?

  Anesthesiology 20021101

• Comparative spinal neurotoxicity of prilocaine and lidocaine.

  Anesthesiology 20021101

• Treatment of tendopathies with tropisetron.

  Rheumatology international 20021101

• Evaluation of a novel topical anesthetic agent for cutaneous laser resurfacing: a randomized comparison study.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20021101

• Topical anesthetics for intravenous insertion in children: a randomized equivalency study.

  Pediatrics 20021001

• Topical anaesthesia to reduce pain associated with carpal tunnel surgery.

  Journal of hand surgery (Edinburgh, Scotland) 20021001

• Local anesthesia: advances in agents and techniques.

  Dental clinics of North America 20021001

• Effective topical anesthetic agents and techniques.

  Dental clinics of North America 20021001

• Randomized, placebo-controlled treatment of anal fissure by lidocaine, EMLA, and GTN in children.

  Journal of pediatric surgery 20020901

• EMLA cream and intraperitoneal lidocaine decrease intraoperative pain during postpartum tubal sterilization.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20020901

• Stability-indicating HPLC assays for the determination of prilocaine and procaine drug combinations.

  Journal of pharmaceutical and biomedical analysis 20020822

• Amphiphilic effects of local anesthetics on rotational mobility in neuronal and model membranes.

  Biochimica et biophysica acta 20020819

• Treatment of pseudofolliculitis barbae in skin types IV, V, and VI with a long-pulsed neodymium:yttrium aluminum garnet laser.

  Journal of the American Academy of Dermatology 20020801

• Intravenous regional anesthesia (Bier's block) for botulinum toxin therapy of palmar hyperhidrosis is safe and effective.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20020801

• Methemoglobinemia in an infant receiving nitric oxide after the use of eutectic mixture of local anesthetic.

  The Journal of pediatrics 20020801

• Anaesthetic and postoperative analgesic effects of spinal clonidine as an additive to prilocaine in the transurethral resection of urinary bladder tumours.

  European journal of anaesthesiology 20020801

• Verification of protector effect of the norepinephrine and felypressin upon the cardiovascular system under action of the lidocaine hydrochloride and prilocaine hydrochloride in anesthetized rats.

  Pharmacological research 20020801

• Use of EMLA cream with vasectomy.

  Urology 20020701

• Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Tape stripping the stratum corneum and the effectiveness of EMLA.

  Emergency medicine journal : EMJ 20020701

• An improved technique for the application of topical anaesthetic cream to skin graft donor sites.

  British journal of plastic surgery 20020701

• Lidocaine iontophoresis versus eutectic mixture of local anesthetics (EMLA) for IV placement in children.

  Anesthesia and analgesia 20020601

• A clinical study to evaluate the efficacy of ELA-Max (4% liposomal lidocaine) as compared with eutectic mixture of local anesthetics cream for pain reduction of venipuncture in children.

  Pediatrics 20020601

• The use of glyceryl trinitrate ointment with EMLA cream for i.v. cannulation in children undergoing routine surgery.

  Anaesthesia and intensive care 20020601

• Intravenous regional blocks with guanethidine and prilocaine combined with physiotherapy: two children with complex regional pain syndrome, type 1.

  European journal of anaesthesiology 20020501

• Single injection digital block: comparison between three techniques.

  Chirurgie de la main 20020501

• Use of lidocaine-prilocaine patch to decrease intramuscular injection pain does not adversely affect the antibody response to diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae type b conjugate and hepatitis B vaccines in infants from birth to six months of age.

  The Pediatric infectious disease journal 20020501

• Lidocaine-prilocaine cream versus tetracaine gel for procedural pain in children.

  The Annals of pharmacotherapy 20020401

• Intravenous regional guanethidine blockade in the treatment of post-traumatic complex regional pain syndrome type 1 (algodystrophy) of the hand.

  The Journal of bone and joint surgery. British volume 20020401

• [Management of leg ulcers in the elderly].

  Revue de l'infirmiere 20020401

• EMLA cream-induced irritant contact dermatitis.

  Journal of cutaneous pathology 20020301

• Vascular and neural mechanisms of ACh-mediated vasodilation in the forearm cutaneous microcirculation.

  Journal of applied physiology (Bethesda, Md. : 1985) 20020201

• A comparison of prilocaine and lidocaine for intravenous regional anaesthesia for forearm fracture reduction in children.

  Paediatric anaesthesia 20020201

• EMLA cream prior to digital nerve block for ingrown nail surgery does not reduce pain at injection of anesthetic solution.

  Acta anaesthesiologica Scandinavica 20020201

• Characteristics of drug substances in oily solutions. Drug release rate, partitioning and solubility.

  International journal of pharmaceutics 20020131

• Local anesthesia with EMLA cream for maxillary sinus puncture.

  The Annals of otology, rhinology, and laryngology 20020101

• Reader questions pain and peritumoral injection.

  Oncology nursing forum 20020101

• Reducing venipuncture and intravenous insertion pain with eutectic mixture of local anesthetic: a meta-analysis.

  Nursing research 20020101

• Amethocaine-lidocaine cream, a new topical formulation for preventing venopuncture-induced pain in children.

  Regional anesthesia and pain medicine 20020101

• Suppression of spontaneous scratching in hairless rats by sedatives but not by antipruritics.

  Skin pharmacology and applied skin physiology 20020101

• [New indication for EMLA creme. Significant reduction of pain in mechanical would debridement].

  Krankenpflege Journal 20020101

• [Comparative efficiency of local anesthetics from the group of complex amides during therapeutic stomatological interventions].

  Stomatologiia 20020101

• Anesthesia with EMLA cream for botulinum A toxin injection into eyelids.

  Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20020101

• Investigation of previously reported mucosal swellings after injection with Citanest Forte.

  Anesthesia progress 20020101

• The tumescent facial block: tumescent local anesthesia and nerve block anesthesia for full-face laser resurfacing.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20011201

• Topical anesthetics update: EMLA and beyond.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20011201

• Quality of anaesthesia for insertion of tension-free vaginal tape using local analgesia and sedation.

  European journal of anaesthesiology 20011101

• Reflection spectroscopy of analgesized skin.

  Microvascular research 20011101

• Pain experience during transvaginal aspiration of immature oocytes.

  Acta obstetricia et gynecologica Scandinavica 20011101

• Blood flow changes in human dental pulps when capsaicin is applied to the adjacent gingival mucosa.

  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20011101

• A randomized double-blind, placebo-controlled trial of the EMLA patch for the reduction of pain associated with intramuscular injection in four to six-year-old children.

  Acta paediatrica (Oslo, Norway : 1992) 20011101

• Efficacy of subcutaneous and topical local anaesthesia for pain relief after resection of malignant breast tumours.

  The European journal of surgery = Acta chirurgica 20011101

• [Can treatment of flat angiomas be proposed in the first months of life?].

  Annales de dermatologie et de venereologie 20011101

• Antimicrobial activity of ropivacaine and other local anaesthetics.

  European journal of anaesthesiology 20011001

• Re: reduction in pain associated with open carpal tunnel decompression.

  Journal of hand surgery (Edinburgh, Scotland) 20011001

• EMLA or Ametop, and for how long?

  Anaesthesia 20011001

• EMLA--1 h is not enough for venous cannulation.

  Anaesthesia 20011001

• [New uses of EMLA: anesthesia for relief of pain caused by hemorrhoid thrombosis].

  Revista espanola de anestesiologia y reanimacion 20011001

• Pain on injection of prilocaine plain vs. lidocaine with epinephrine. A prospective double-blind study.

  Journal of the American Dental Association (1939) 20011001

• Plasma concentrations of lignocaine and prilocaine after a 24-h application of analgesic cream (EMLA) to leg ulcers.

  The British journal of dermatology 20011001

• EMLA versus nitrous oxide for venous cannulation in children.

  Anesthesia and analgesia 20010901

• Methemoglobinemia.

  The Western journal of medicine 20010901

• Clinical and radiographic evaluation of pulpotomies performed under intrapulpal injection of anaesthetic solution.

  International endodontic journal 20010901

• The efficacy of a range of contact media as coupling agents in extracorporeal shockwave lithotripsy.

  BJU international 20010901

• Topical anesthesia with or without propofol sedation versus retrobulbar/peribulbar anesthesia for cataract extraction: prospective randomized trial.

  Journal of cataract and refractive surgery 20010901

• The effect of lidocaine/prilocaine cream on an experimental wound healing model.

  European journal of emergency medicine : official journal of the European Society for Emergency Medicine 20010901

• [Ovarian puncture in fertilization in vitro: what analgesia?].

  Gynecologie, obstetrique & fertilite 20010901

• Topical anesthetics in children: agents and techniques that equally comfort patients, parents, and clinicians.

  Current opinion in pediatrics 20010801

• Differentiation by in vitro treatment of lidocaine-epinephrine and prilocaine-felypressine in neutrophils.

  Immunology letters 20010702

• Effects of prilocaine and articaine on human leucocytes and reactive oxygen species in vitro.

  Acta anaesthesiologica Scandinavica 20010701

• Hot chili, a cook and EMLA.

  Acta anaesthesiologica Scandinavica 20010701

• A comparison of 1% prilocaine with 0.5% ropivacaine for outpatient-based surgery under axillary brachial plexus block.

  Anesthesia and analgesia 20010701

• [Percutaneous topical anaesthesia applications in ocular surgery].

  Archivos de la Sociedad Espanola de Oftalmologia 20010701

• Intrapocket anesthesia for scaling and root planing: results of a double-blind multicenter trial using lidocaine prilocaine dental gel.

  Journal of periodontology 20010701

• Eutectic mixture of local anesthetics reduces pain during intravenous catheter insertion in the pediatric patient.

  The Clinical journal of pain 20010601

• 1% lidocaine injection, EMLA cream, or 'numby stuff' for topical analgesia associated with peripheral intravenous cannulation.

  AANA journal 20010601

• The influence of two different dental local anaesthetic solutions on the haemodynamic responses of children undergoing restorative dentistry: a randomised, single-blind, split-mouth study.

  British dental journal 20010512

• Plasma levels of lidocaine and prilocaine after application of Oraqix, a new intrapocket anesthetic, in patients with advanced periodontitis.

  Journal of clinical periodontology 20010501

• The anesthetic onset and duration of a new lidocaine/prilocaine gel intra-pocket anesthetic (Oraqix) for periodontal scaling/root planing.

  Journal of clinical periodontology 20010501

• Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. EMLA or amethocaine (tetracaine) for topical analgesia in children.

  Emergency medicine journal : EMJ 20010501

• Emla versus ice as a topical anesthetic.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20010501

• Comparison of the effect of lidocaine-epinephrine and prilocaine-felypressine to alter macrophage functions.

  International immunopharmacology 20010501

• [Varicose vein operations with tumescence local anesthesia--an effective method].

  Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 20010501

• A randomised, double-blind, placebo-controlled, comparative study of topical skin analgesics and the anxiety and discomfort associated with venous cannulation.

  British dental journal 20010428

• [Comment on the article 'Use of EMLA cream and ropivacaine indacryocystorhinostomy with locoregional anesthesia and sedation'].

  Revista espanola de anestesiologia y reanimacion 20010401

• [Citanest recalled--bad and inconsistent decision by Astra pharmaceutical company].

  Lakartidningen 20010307

• LET versus EMLA for pretreating lacerations: a randomized trial.

  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20010301

• Split-skin grafting with lidocaine-prilocaine cream: A meta-analysis of efficacy and safety in geriatric versus nongeriatric patients.

  Plastic and reconstructive surgery 20010301

• Factors affecting patients' and potential patients' choices among anaesthetics for periodontal recall visits.

  Journal of dentistry 20010301

• Lidocaine and prilocaine toxicity in a patient receiving treatment for mollusca contagiosa.

  Journal of the American Academy of Dermatology 20010201

• Comparison of EMLA cream versus placebo in children receiving distraction therapy for venepuncture.

  Acta paediatrica (Oslo, Norway : 1992) 20010201

• Oral sucrose compares favourably with lidocaine-prilocaine cream for pain relief during venepuncture in neonates.

  Acta paediatrica (Oslo, Norway : 1992) 20010201

• Hyperpigmentation following the use of Emla cream.

  British journal of plastic surgery 20010101

• Comparison of topical EMLA 5% oral adhesive to benzocaine 20% on the pain experienced during palatal anesthetic infiltration in children.

  Pediatric dentistry 20010101

• Pain management for neonatal circumcision.

  Paediatric drugs 20010101

• EMLA anaesthetic cream for sharp leg ulcer debridement: a review of the clinical evidence for analgesic efficacy and tolerability.

  European journal of dermatology : EJD 20010101

• Evaluation of pain management interventions for neonatal circumcision pain.

  Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners 20010101

• Safety and pharmacokinetics of EMLA in the treatment of postburn pruritus in pediatric patients: a pilot study.

  The Journal of burn care & rehabilitation 20010101

• [Anesthesia with EMLA cream: a promising application for plastic surgery].

  Revista espanola de anestesiologia y reanimacion 20010101

• The use of EMLA for an intraoral soft-tissue biopsy in a needle phobic: a case report.

  Anesthesia progress 20010101

• Effect of an intervention to reduce procedural pain and distress for children with HIV infection.

  Journal of pediatric psychology 20010101

• [Some aspects of epidural anesthesia in patients with chronic renal insufficiency].

  Likars'ka sprava 20010101

• Local anesthesia prior to the insertion of peripherally inserted central catheters.

  Journal of infusion nursing : the official publication of the Infusion Nurses Society 20010101

• Noninvasive drug delivery.

  Comprehensive therapy 20010101

• [Experiences with liposuction of established surgeons].

  Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress 20010101

• Dermatosurgery using subcutaneous infusion anesthesia with prilocaine and ropivacaine in children.

  Pediatric dermatology 20010101

• Subcutaneous infusion anesthesia for dermatologic surgery in children: are we ready?

  Pediatric dermatology 20010101

• Use of EMLA: is it an injection free alternative?

  The Journal of clinical pediatric dentistry 20010101

• [Ointment-induced local anesthesia as an anesthesia method for maxillary sinus puncture].

  Duodecim; laaketieteellinen aikakauskirja 20010101

• Vulvar biopsy. Techniques for reducing patient discomfort.

  Advance for nurse practitioners 20010101

• Using a topical anaesthetic cream to reduce pain during sharp debridement of chronic leg ulcers.

  Journal of wound care 20010101

• The incidence of transient neurological symptoms after spinal anaesthesia with lidocaine compared to prilocaine.

  Anaesthesia 20001001

• CNS toxicity after topical application of EMLA cream on a toddler with molluscum contagiosum.

  Pediatric emergency care 20000801

• Prilocaine versus lignocaine for minor lid procedures.

  Eye (London, England) 20000801

• [Comparative study between 5% prilocaine and 2% mepivacaine by the subarachnoid route in transurethral resections].

  Revista espanola de anestesiologia y reanimacion 20000501

• Adverse effects associated with EMLA cream used as topical anesthetic for the mechanical debridement of leg ulcers.

  Journal of the American Academy of Dermatology 20000101

• Effects of single and repeated applications of a eutectic mixture of local anaesthetics (EMLA) cream on spontaneous and evoked pain in post-herpetic neuralgia.

  Pain 19990501

• Topical EMLA pre-treatment fails to decrease the pain induced by 1% topical capsaicin.

  Pain 19990401

• Effect of EMLA pre-treatment on capsaicin-induced burning and hyperalgesia.

  Acta dermato-venereologica 19990301

• [Convulsions after EMLA cream application].

  Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 19990101

• Transient neurologic symptoms after spinal anesthesia: a lower incidence with prilocaine and bupivacaine than with lidocaine.

  Anesthesiology 19980301

• Inadequate tourniquet inflation associated with a case of prilocaine toxicity.

  European journal of anaesthesiology 19980301

• The effect of different anaesthetic agents in hearing loss following spinal anaesthesia.

  European journal of anaesthesiology 19980101

• [Antipruritic effect of antihistaminic and local anesthetic topical agents after iontophoretic histamine stimulation].

  Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 19960501

• The use of lignocaine to reduce pain on i.v. injection of diluted nalbuphine.

  European journal of anaesthesiology 19950901

• Prilocaine reduces injection pain caused by propofol.

  Acta anaesthesiologica Scandinavica 19950201

• Intravenous regional anaesthesia with 0.5% prilocaine or 0.5% chloroprocaine. A double-blind comparison in volunteers.

  Anaesthesia 19920701

• Lidocaine/prilocaine cream (EMLA(R)) versus infiltration anaesthesia: a comparison of the analgesic efficacy for punch biopsy and electrocoagulation of genital warts in men.

  Genitourinary medicine 19920601

• Postoperative pain experience after gingivectomies using different combinations of local anaesthetic agents and periodontal dressings.

  Journal of clinical periodontology 19910301

• Structure activity relationships of selected benzodiazepines as anticonvulsants to local anesthetics.

  Pharmacology and therapeutics in dentistry 19800101

• Clinical pharmacokinetics of local anaesthetics.

  Canadian Anaesthetists' Society journal 19770301

• Effect of intravenous citanest on adrenaline-induced ventricular fibrillation during chloroform anaesthesia.

  The Journal of the Egyptian Medical Association 19760101

• Spinal analgesic agents. A comparison of cinchocaine, lignocaine and prilocaine.

  Anaesthesia 19710701

• Continuous intrapartum lumbar epidural block: a comparative study employing propitocaine 2 percent, lidocaine 1.5 percent with epinephrine, and 1.5 percent lidocaine.

  Southern medical journal 19710401