179248-59-0 | 4-Quinazolinamine, 6,7-dimethoxy-N-(4-phenoxyphenyl)-

Packsize	Purity	Availability	Price	Discounted Price
1mg	99%	in stock	$22.00	$15.00
5mg	99%	in stock	$40.00	$28.00
10mg	99%	in stock	$50.00	$35.00
25mg	99%	in stock	$60.00	$42.00
50mg	99%	in stock	$75.00	$52.00
100mg	99%	in stock	$96.00	$67.00
250mg	99%	in stock	$142.00	$99.00
1g	99%	in stock	$346.00	$242.00

Description

• Catalog Number: AB02018
• Chemical Name: 4-Quinazolinamine, 6,7-dimethoxy-N-(4-phenoxyphenyl)-
• CAS Number: 179248-59-0
• Molecular Formula: C22H19N3O3
• Molecular Weight: 373.4046
• MDL Number: MFCD01815300
• SMILES: COc1cc2c(ncnc2cc1OC)Nc1ccc(cc1)Oc1ccccc1

Computed Properties

• Complexity: 466
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 28
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 6
• XLogP3: 4.9

Literature

• A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.

  The Biochemical journal 20130415

• Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.

  Nature biotechnology 20111101

• Protein kinase G type Ialpha activity in human ovarian cancer cells significantly contributes to enhanced Src activation and DNA synthesis/cell proliferation.

  Molecular cancer research : MCR 20100401

• The selectivity of protein kinase inhibitors: a further update.

  The Biochemical journal 20071215

• Frontal affinity chromatography with MS detection of EphB2 tyrosine kinase receptor. 2. Identification of small-molecule inhibitors via coupling with virtual screening.

  Journal of medicinal chemistry 20050505

• Frontal affinity chromatography with MS detection of EphB2 tyrosine kinase receptor. 1. Comparison with conventional ELISA.

  Journal of medicinal chemistry 20041007

• Structural determinants for potent, selective dual site inhibition of human pp60c-src by 4-anilinoquinazolines.

  Biochemistry 20010619