179463-17-3 | Caspofungin acetate

Packsize	Purity	Availability	Price	Discounted Price
1mg	97%	in stock	$42.00	$29.00
5mg	97%	in stock	$76.00	$53.00
10mg	97%	in stock	$137.00	$96.00
25mg	97%	in stock	$257.00	$180.00
50mg	97%	in stock	$444.00	$311.00
100mg	97%	in stock	$856.00	$599.00

Description

• Catalog Number: AB02221
• Chemical Name: Caspofungin acetate
• CAS Number: 179463-17-3
• Molecular Formula: C56H96N10O19
• Molecular Weight: 1213.417
• MDL Number: MFCD08141839
• SMILES: CC(=O)O.CC(=O)O.NCCN[C@H]1NC(=O)C2[C@@H](O)CCN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]2N(C(=O)[C@@H](NC(=O)[C@H](C[C@@H]1O)NC(=O)CCCCCCCCC(CC(CC)C)C)[C@H](O)C)C[C@@H](C2)O)[C@@H]([C@H](c1ccc(cc1)O)O)O)[C@@H](CCN)O

Computed Properties

• Complexity: 1930
• Covalently-Bonded Unit Count: 3
• Defined Atom Stereocenter Count: 14
• Heavy Atom Count: 85
• Hydrogen Bond Acceptor Count: 22
• Hydrogen Bond Donor Count: 18
• Rotatable Bond Count: 23
• Undefined Atom Stereocenter Count: 2

Literature

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  Comparative immunology, microbiology and infectious diseases 20151001

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  Antimicrobial agents and chemotherapy 20140501

• Killing rates exerted by caspofungin in 50 % serum and its correlation with in vivo efficacy in a neutropenic murine model against Candida krusei and Candida inconspicua.

  Journal of medical microbiology 20140201

• In vitro pharmacodynamics and in vivo efficacy of fluconazole, amphotericin B and caspofungin in a murine infection by Candida lusitaniae.

  International journal of antimicrobial agents 20140201

• Efficacy of the combination of voriconazole and caspofungin in experimental pulmonary aspergillosis by different Aspergillus species.

  Mycopathologia 20140101

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  Journal of natural products 20130322

• Posaconazole exhibits in vitro and in vivo synergistic antifungal activity with caspofungin or FK506 against Candida albicans.

  PloS one 20130101

• The nonsteroidal antiinflammatory drug diclofenac potentiates the in vivo activity of caspofungin against Candida albicans biofilms.

  The Journal of infectious diseases 20121201

• Heat shock protein 90 is required for conidiation and cell wall integrity in Aspergillus fumigatus.

  Eukaryotic cell 20121101

• Mutual influence of backbone proline substitution and lipophilic tail character on the biological activity of simplified analogues of caspofungin.

  Organic & biomolecular chemistry 20121007

• First case of breakthrough pneumonia due to Aspergillus nomius in a patient with acute myeloid leukemia.

  Medical mycology 20121001

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• β(1,3)-glucan synthase complex from Alternaria infectoria, a rare dematiaceous human pathogen.

  Medical mycology 20121001

• Comparison of in vitro and vivo efficacy of caspofungin against Candida parapsilosis, C. orthopsilosis, C. metapsilosis and C. albicans.

  Mycopathologia 20121001

• CRS-MIS in Candida glabrata: sphingolipids modulate echinocandin-Fks interaction.

  Molecular microbiology 20121001

• Interactions of liposome carriers with infectious fungal hyphae reveals the role of β-glucans.

  Molecular pharmaceutics 20120904

• Successful treatment of cutaneous alternariosis with caspofungin in a renal transplant recipient.

  Mycoses 20120901

• Echinocandin resistance due to simultaneous FKS mutation and increased cell wall chitin in a Candida albicans bloodstream isolate following brief exposure to caspofungin.

  Journal of medical microbiology 20120901

• [Fungal infection secondary to treatment of Escherichia coli in a critically ill patient].

  Ugeskrift for laeger 20120827

• Plasma concentrations of caspofungin at two different dosage regimens in a patient with hepatic dysfunction.

  Transplant infectious disease : an official journal of the Transplantation Society 20120801

• Fatal bronchial invasion of Scopulariopsis brevicaulis in an acute monocytic leukemia patient.

  Diagnostic microbiology and infectious disease 20120801

• Synthesis and antifungal activities of glycosylated derivatives of the cyclic peptide fungicide caspofungin.

  ChemMedChem 20120801

• Histoplasmosis in HIV-positive patients in Ceará, Brazil: clinical-laboratory aspects and in vitro antifungal susceptibility of Histoplasma capsulatum isolates.

  Transactions of the Royal Society of Tropical Medicine and Hygiene 20120801

• A prospective, randomized study of empirical antifungal therapy for the treatment of chemotherapy-induced febrile neutropenia in children.

  British journal of haematology 20120701

• Breakthrough trichosporonosis in patients receiving echinocandins: case report and literature review.

  Chinese medical journal 20120701

• Comparison of the Etest and a rapid flow cytometry-based method with the reference CLSI broth microdilution protocol M27-A3 for the echinocandin susceptibility testing of Candida spp.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20120601

• Minimal inhibitory concentration (MIC) of caspofungin and itraconazole inhibiting growth of Candida strains calculated from the linear regression equation.

  Advances in medical sciences 20120601

• Fluconazole exposure rather than clonal spreading is correlated with the emergence of Candida glabrata with cross-resistance to triazole antifungal agents.

  The Kaohsiung journal of medical sciences 20120601

• Hepatic safety of caspofungin during treatment of invasive fungal diseases in elderly patients.

  Chinese medical journal 20120601

• In vitro and in vivo susceptibility of two-drug and three-drug combinations of terbinafine, itraconazole, caspofungin, ibuprofen and fluvastatin against Pythium insidiosum.

  Veterinary microbiology 20120525

• Pharmacoeconomic analysis of voriconazole vs. caspofungin in the empirical antifungal therapy of febrile neutropenia in Australia.

  Mycoses 20120501

• The activity of echinocandins, amphotericin B and voriconazole against fluconazole-susceptible and fluconazole-resistant Brazilian Candida glabrata isolates.

  Memorias do Instituto Oswaldo Cruz 20120501

• Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata.

  PLoS pathogens 20120501

• Vacuolar H(+)-ATPase plays a key role in cell wall biosynthesis of Aspergillus niger.

  Fungal genetics and biology : FG & B 20120401

• Breakthrough invasive mould infections in patients treated with caspofungin.

  The Journal of infection 20120401

• Total synthesis and structure-activity relationships of new echinocandin-like antifungal cyclolipohexapeptides.

  European journal of medicinal chemistry 20120401

• Caspofungin for prophylaxis and treatment of fungal infections in adolescents and adults: a meta-analysis of randomized controlled trials.

  Die Pharmazie 20120401

• Pseudomembranous necrotizing tracheobronchial aspergillosis: an analysis of 16 cases.

  Chinese medical journal 20120401

• Use of antifungal agents in pediatric and adult high-risk areas.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20120301

• [Study on in vitro susceptibility of Candida spp. isolated from blood culture].

  Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20120301

• A randomized, double-blind, prospective study of caspofungin vs. amphotericin B for the treatment of invasive candidiasis in newborn infants.

  Journal of tropical pediatrics 20120201

• Antifungal susceptibility of ocular fungal pathogens recovered from around the world against itraconazole, voriconazole, amphotericin B, and caspofungin.

  Medical mycology 20120201

• The reversed halo sign as the initial radiographic sign of pulmonary zygomycosis.

  Infection 20120201

• Long-term treatment of invasive sinus, tracheobroncheal, pulmonary and intracerebral aspergillosis in acute lymphoblastic leukaemia.

  Infection 20120201

• Multiple subcutaneous cysts due to Exophiala spinifera in an immunocompetent patient.

  Medical mycology 20120201

• Outbreak of invasive aspergillosis after major heart surgery caused by spores in the air of the intensive care unit.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20120201

• Effect of nikkomycin Z and 50% human serum on the killing activity of high-concentration caspofungin against Candida species using time-kill methodology.

  Journal of chemotherapy (Florence, Italy) 20120201

• Caspofungin: when and how? The microbiologist's view.

  Mycoses 20120101

• Addition of DNase improves the in vitro activity of antifungal drugs against Candida albicans biofilms.

  Mycoses 20120101

• Broth microdilution and time-kill testing of Caspofungin, voriconazole, amphotericin B and their combinations against clinical isolates of Candida krusei.

  Mycopathologia 20120101

• Antifungal management and resource use in patients with acute myeloid leukaemia after chemotherapy--retrospective analysis of changes over 3 yr in a German hospital.

  European journal of haematology 20120101

• Antifungal treatment affects the laboratory diagnosis of invasive aspergillosis.

  Journal of clinical pathology 20120101

• Role of caspofungin in restoring the impaired phagocyte-dependent innate immunity towards Candida albicans in chronic haemodialysis patients.

  International journal of antimicrobial agents 20120101

• Ten-year experience with fungal peritonitis in peritoneal dialysis patients: antifungal susceptibility patterns in a North-American center.

  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20120101

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• Echinocandin use in the neonatal intensive care unit.

  The Annals of pharmacotherapy 20120101

• Disseminated candidemia refractory to caspofungin therapy in an infant with extremely low birth weight.

  Journal of the Formosan Medical Association = Taiwan yi zhi 20120101

• Peptides of the constant region of antibodies display fungicidal activity.

  PloS one 20120101

• Caspofungin for treatment of invasive aspergillosis in Germany: results of a pre-planned subanalysis of an international registry.

  European journal of medical research 20120101

• Microcolony imaging of Aspergillus fumigatus treated with echinocandins reveals both fungistatic and fungicidal activities.

  PloS one 20120101

• Comparison of the kidney fungal burden in experimental disseminated candidiasis by species of the Candida parapsilosis complex treated with fluconazole, amphotericin B and caspofungin in a temporarily neutropenic murine model.

  Chemotherapy 20120101

• Caspofungin as antifungal prophylaxis in pediatric patients undergoing allogeneic hematopoietic stem cell transplantation: a retrospective analysis.

  BMC infectious diseases 20120101

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  Medecine sciences : M/S 20120101

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  PloS one 20120101

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  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20120101

• Successful treatment of liver aspergilloma by caspofungin acetate first-line therapy in a non-immunocompromised patient.

  International journal of molecular sciences 20120101

• Fatal post-operative Trichoderma longibrachiatum mediastinitis and peritonitis in a paediatric patient with complex congenital cardiac disease on peritoneal dialysis.

  Journal of medical microbiology 20111201

• Treatment of chronic pulmonary blastomycosis with caspofungin.

  Journal of medical microbiology 20111201

• Overview of safety experience with caspofungin in clinical trials conducted over the first 15 years: a brief report.

  International journal of antimicrobial agents 20111201

• Fungicidal activity of the human peptide hepcidin 20 alone or in combination with other antifungals against Candida glabrata isolates.

  Peptides 20111201

• Efg1 Controls caspofungin-induced cell aggregation of Candida albicans through the adhesin Als1.

  Eukaryotic cell 20111201

• Lack of response in severe pneumocystis pneumonia to combined caspofungin and clindamycin treatment: a case report.

  Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20111201

• [Echinocandins].

  Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia 20111201

• An on-line solid phase extraction procedure for the routine quantification of caspofungin by liquid chromatography-tandem mass spectrometry.

  Clinical chemistry and laboratory medicine 20111130

• Successful treatment with echinocandin in an HIV-infected individual failing first-line therapy for Pneumocystis jirovecii pneumonia.

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• Efficacy and safety of micafungin for treatment of serious Candida infections in patients with or without malignant disease.

  Mycoses 20111101

• Antifungal susceptibility and virulence attributes of bloodstream isolates of Candida from Hong Kong and Finland.

  Mycopathologia 20111101

• In vitro activity of a novel broad-spectrum antifungal, E1210, tested against Aspergillus spp. determined by CLSI and EUCAST broth microdilution methods.

  Antimicrobial agents and chemotherapy 20111101

• In vitro effectiveness of antifungal lock solutions on catheters infected with Candida species.

  Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20111001

• Efficacy and safety of caspofungin in obese patients.

  Medical mycology 20111001

• In vitro activity of a novel broad-spectrum antifungal, E1210, tested against Candida spp. as determined by CLSI broth microdilution method.

  Diagnostic microbiology and infectious disease 20111001

• In vitro interaction of caspofungin and immunosuppressives against agents of mucormycosis.

  The Journal of antimicrobial chemotherapy 20111001

• Post-antifungal effects and time-kill studies of anidulafungin, caspofungin, and micafungin against Candida glabrata and Candida parapsilosis.

  Diagnostic microbiology and infectious disease 20111001

• Hospital costs and outcomes among intravenous antifungal therapies for patients with invasive aspergillosis in the United States.

  Mycoses 20110901

• Detailed comparison of Candida albicans and Candida glabrata biofilms under different conditions and their susceptibility to caspofungin and anidulafungin.

  Journal of medical microbiology 20110901

• Successful treatment of central venous catheter infection due to Candida lipolytica by caspofungin-lock therapy.

  Mycoses 20110901

• Evaluation of antifungal therapy in patients with candidaemia based on susceptibility testing results: implications for antimicrobial stewardship programmes.

  The Journal of antimicrobial chemotherapy 20110901

• A randomized comparison of caspofungin versus antifungal prophylaxis according to investigator policy in acute leukaemia patients undergoing induction chemotherapy (PROFIL-C study).

  The Journal of antimicrobial chemotherapy 20110901

• The evaluation of in vitro pharmacodynamic properties of amphotericin B, voriconazole and caspofungin against A. fumigatus isolates by the conventional and colorimetric time-kill assays.

  Medical mycology 20110801

• Pga26 mediates filamentation and biofilm formation and is required for virulence in Candida albicans.

  FEMS yeast research 20110801

• A novel assay of biofilm antifungal activity reveals that amphotericin B and caspofungin lyse Candida albicans cells in biofilms.

  Yeast (Chichester, England) 20110801

• [Outcome analysis of caspofungin in combination with voriconazole for treatment of 12 hematologic malignancies cases with invasive fungal infection].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110801

• Rhodotorula mucilaginosa catheter-related fungaemia in a patient with multiple myeloma.

  Mycoses 20110701

• Invasive aspergillosis caused by Aspergillus terreus in a living donor liver transplant recipient successfully treated by caspofungin.

  Mycoses 20110701

• Fungicidal activity and morphological alterations of Candida albicans induced by echinocandins: study of strains with reduced caspofungin susceptibility.

  Mycoses 20110701

• Retrospective evaluation of caspofungin therapy in invasive aspergillosis (RECAM-IA).

  Mycoses 20110701

• Intraocular caspofungin: in vitro safety profile for human ocular cells.

  Mycoses 20110701

• A Candida albicans strain with high MIC for caspofungin and no FKS1 mutations exhibits a high chitin content and mutations in two chitinase genes.

  Medical mycology 20110701

• Economic evaluation of caspofungin versus liposomal amphotericin B for empirical antifungal therapy in patients with persistent fever and neutropenia in Sweden.

  Scandinavian journal of infectious diseases 20110701

• Pharmacokinetics of caspofungin in a critically ill patient with liver cirrhosis.

  European journal of clinical pharmacology 20110701

• [Diagnosis and treatment of pneumocystis jirovecii pneumonia].

  Deutsche medizinische Wochenschrift (1946) 20110701

• Aspergillus fumigatus joint infection: a review.

  Seminars in arthritis and rheumatism 20110601

• A trial of caspofungin salvage treatment in PCP pneumonia.

  Thorax 20110601

• Antifungal susceptibility of bloodstream Candida isolates in Sfax hospital: Tunisia.

  Mycopathologia 20110601

• Candida utilis candidaemia in neonatal patients.

  Journal of medical microbiology 20110601

• Clinical breakpoints for the echinocandins and Candida revisited: integration of molecular, clinical, and microbiological data to arrive at species-specific interpretive criteria.

  Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20110601

• Comparative in vivo dose-dependent activity of caspofungin and anidulafungin against echinocandin-susceptible and -resistant Aspergillus fumigatus.

  The Journal of antimicrobial chemotherapy 20110601

• Calcineurin controls drug tolerance, hyphal growth, and virulence in Candida dubliniensis.

  Eukaryotic cell 20110601

• Selection of resistant fungi in liver transplant recipients during use of newer antifungal agents -- a report of two cases.

  Annals of the Academy of Medicine, Singapore 20110601

• An accidental mass.

  Lancet (London, England) 20110521

• A rescue therapy with a combination of caspofungin and liposomal amphotericin B or voriconazole in children with haematological malignancy and refractory invasive fungal infections.

  Mycoses 20110501

• European guidelines for antifungal management in leukemia and hematopoietic stem cell transplant recipients: summary of the ECIL 3--2009 update.

  Bone marrow transplantation 20110501

• Breakthrough Saprochaete capitata infections in patients receiving echinocandins: case report and review of the literature.

  Medical mycology 20110501

• Invasive aspergillosis in patients with liver disease.

  Medical mycology 20110501

• In vitro interaction of itraconazole with amphotericin B, caspofungin, and terbinafine against clinical isolates of Trichosporon asahii.

  Mycopathologia 20110501

• [Fatal outcome of invasive tracheal aspergillosis].

  RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 20110501

• Galactomannan-guided preemptive vs. empirical antifungals in the persistently febrile neutropenic patient: a prospective randomized study.

  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20110501

• Treatment of Alternaria keratitis with intrastromal and topical caspofungin in combination with intrastromal, topical, and oral voriconazole.

  The Annals of pharmacotherapy 20110501

• Scopulariopsis brevicaulis abscess in a child treated for myeloblastic leukaemia.

  The Lancet. Infectious diseases 20110501

• [Echinocandins in children].

  Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20110501

• Catheter-associated aspergillosis of the chest wall following allogeneic hematopoietic stem cell transplantation.

  Transplant infectious disease : an official journal of the Transplantation Society 20110401

• Aspergillus thyroiditis in a renal transplant recipient mimicking subacute thyroiditis.

  Transplant infectious disease : an official journal of the Transplantation Society 20110401

• In vitro interactions among echinocandins against Aspergillus fumigatus: lack of concordance among methods.

  Medical mycology 20110401

• Candida bloodstream infections in intensive care units: analysis of the extended prevalence of infection in intensive care unit study.

  Critical care medicine 20110401

• Multilaboratory testing of two-drug combinations of antifungals against Candida albicans, Candida glabrata, and Candida parapsilosis.

  Antimicrobial agents and chemotherapy 20110401

• Comparative in vitro susceptibility of clinical isolates of Candida paparsilosis complex and other Candida species to caspofungin and anidulafungin by Etest.

  Journal of chemotherapy (Florence, Italy) 20110401

• Efficacy of a single 6 mg/kg versus two 3 mg/kg caspofungin doses for treatment of disseminated candidiasis caused by Candida albicans in a neutropenic mouse model.

  Journal of chemotherapy (Florence, Italy) 20110401

• Antifungal use in hospitalized adults in U.S. academic health centers.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110301

• Caspofungin therapy in immunocompromised children and neonates.

  Expert review of anti-infective therapy 20110301

• In vitro activity of echinocandins against non-Candida albicans: is echinocandin antifungal activity the same?

  Enfermedades infecciosas y microbiologia clinica 20110301

• [Combination therapy for invasive aspergillosis].

  Enfermedades infecciosas y microbiologia clinica 20110301

• Linezolid and clindamycin improve the outcome of severe, necrotizing pneumonia due to community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA).

  Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20110301

• Safety and pharmacokinetics of higher doses of caspofungin in healthy adult participants.

  Journal of clinical pharmacology 20110201

• [Prevalence of Candida parapsilosis, C. orthopsilosis and C. metapsilosis in candidemia over a 5-year period at Nantes hospital and in vitro susceptibility to three echinocandins by E-test®].

  Pathologie-biologie 20110201

• [Emergence of Candida parapsilosis candidemia at Cochin hospital. Characterization of isolates and search for risk factors].

  Pathologie-biologie 20110201

• Caspofungin primes the immune response of the larvae of Galleria mellonella and induces a non-specific antimicrobial response.

  Journal of medical microbiology 20110201

• Outcomes with micafungin in patients with candidaemia or invasive candidiasis due to Candida glabrata and Candida krusei.

  The Journal of antimicrobial chemotherapy 20110201

• Catheter-related candidemia caused by Candida haemulonii in a patient in long-term hospital care.

  Journal of Korean medical science 20110201

• Cell wall integrity is linked to mitochondria and phospholipid homeostasis in Candida albicans through the activity of the post-transcriptional regulator Ccr4-Pop2.

  Molecular microbiology 20110201

• Lack of pharmacokinetic drug interaction between oral posaconazole and caspofungin or micafungin.

  Journal of clinical pharmacology 20110101

• A case of Candida krusei peritonitis secondary to duodenal perforation due to Candida duodenitis.

  Mycopathologia 20110101

• A retrospective analysis of the use of caspofungin in recipients of liver transplant with a modified high index of suspicion for fungal infection. A critical review of mortality, acute cellular rejection, infections, and changes in the liver function tests while on caspofungin.

  Clinical transplantation 20110101

• In vitro activity of the lipopeptide PAL-Lys-Lys-NH2, alone and in combination with antifungal agents, against clinical isolates of Candida spp.

  Peptides 20110101

• Changes in cell wall synthesis and ultrastructure during paradoxical growth effect of caspofungin on four different Candida species.

  Antimicrobial agents and chemotherapy 20110101

• Caspofungin plus posaconazole as salvage therapy of invasive fungal infections in immunocompromised patients.

  Mycoses 20110101

• Determination of the therapeutic activity of caspofungin compared with the amphotericin B in an animal experimental model of histoplasmosis in hamster (Mesocrisetus auratus).

  Revista iberoamericana de micologia 20110101

• Prophylaxis and treatment of invasive aspergillosis with voriconazole, posaconazole and caspofungin: review of the literature.

  European journal of medical research 20110101

• Pharmacology and metabolism of anidulafungin, caspofungin and micafungin in the treatment of invasive candidosis: review of the literature.

  European journal of medical research 20110101

• Treatment and prophylaxis of invasive candidiasis with anidulafungin, caspofungin and micafungin:review of the literature.

  European journal of medical research 20110101

• Treatment and prophylaxis of invasive candidiasis with anidulafungin, caspofungin and micafungin and its impact on use and costs: review of the literature.

  European journal of medical research 20110101

• Conservative management of Candida infection of prosthetic aortic graft by means of caspofungin and fluconazole alone.

  Texas Heart Institute journal 20110101

• Candidemia in children after complex congenital heart defects surgery treated with caspofungin--our own experience and a review of literature.

  Medical science monitor : international medical journal of experimental and clinical research 20110101

• Coexistence of fatal disseminated invasive aspergillosis and pyoderma gangrenosum: a case report.

  Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20110101

• [Cardiac invasive aspergillosis in a heart transplant recipient].

  Revista iberoamericana de micologia 20110101

• [Development of Candida parapsilosis candidemia during caspofungin therapy].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20110101

• Effect of fluid loading during hypovolaemic shock on caspofungin pharmacokinetic parameters in pig.

  Critical care (London, England) 20110101

• Epidemiology, species distribution, antifungal susceptibility and outcome of nosocomial candidemia in a tertiary care hospital in Italy.

  PloS one 20110101

• Rare form of semi-invasive aspergillosis in immunocompetent patient: case report.

  Pneumologia (Bucharest, Romania) 20110101

• Successful treatment of Scedosporium apiospermum soft tissue abscess with caspofungin and voriconazole in a severely immunocompromised patient with acute myeloid leukemia.

  Transplant infectious disease : an official journal of the Transplantation Society 20101201

• Successful treatment of sellar aspergillus abscess.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20101201

• Multiplex ultra-performance liquid chromatography-tandem mass spectrometry method for simultaneous quantification in human plasma of fluconazole, itraconazole, hydroxyitraconazole, posaconazole, voriconazole, voriconazole-N-oxide, anidulafungin, and caspofungin.

  Antimicrobial agents and chemotherapy 20101201

• Characterization of sensor-specific stress response by transcriptional profiling of wsc1 and mid2 deletion strains and chimeric sensors in Saccharomyces cerevisiae.

  Omics : a journal of integrative biology 20101201

• [Caspofungin after solid organ transplantation in Germany: observational study on treatment of invasive fungal infections].

  Der Anaesthesist 20101201

• In vitro evaluation of antibiotic lock technique for the treatment of Candida albicans, C. glabrata, and C. tropicalis biofilms.

  Journal of Korean medical science 20101201

• Evaluating retinal toxicity of intravitreal caspofungin in the mouse eye.

  Investigative ophthalmology & visual science 20101101

• Efficacy of caspofungin as salvage therapy for invasive aspergillosis compared to standard therapy in a historical cohort.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20101101

• In vitro and in vivo antifungal susceptibilities of the Mucoralean fungus Cunninghamella.

  Antimicrobial agents and chemotherapy 20101101

• Recurrent fungal keratitis following penetrating keratoplasty: an unusual source of infection.

  Archives of ophthalmology (Chicago, Ill. : 1960) 20101101

• In vitro paradoxical growth of Pythium insidiosum in the presence of caspofungin.

  Veterinary microbiology 20101026

• Effects of caspofungin, Candida albicans and Aspergillus fumigatus on toll-like receptor 9 of GM-CSF-stimulated PMNs.

  FEMS immunology and medical microbiology 20101001

• Caspofungin versus liposomal amphotericin B: are they really comparable?

  The Pediatric infectious disease journal 20101001

• Pulmonary aspergillosis in a non-neutropenic critical patient.

  The Journal of trauma 20101001

• In vitro susceptibility testing of Aspergillus spp. against voriconazole, itraconazole, posaconazole, amphotericin B and caspofungin.

  Chinese medical journal 20101001

• Successful management of postpneumonectomy Aspergillus pleural empyema by combined surgical and anti-fungal treatment with voriconazole and caspofungin.

  Mycoses 20100901

• Evaluation of the Etest method for susceptibility testing of Aspergillus spp. and Fusarium spp. to three echinocandins.

  Medical mycology 20100901

• Invasive respiratory aspergillosis is a treatable disease with early diagnosis and aggressive therapy.

  Pediatric hematology and oncology 20100901

• Adherence to international guidelines for the treatment of invasive aspergillosis in acute myeloid leukaemia: feasibility and utility (SEIFEM-2008B study).

  The Journal of antimicrobial chemotherapy 20100901

• High rate of breakthrough invasive aspergillosis among patients receiving caspofungin for persistent fever and neutropenia.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20100801

• Cunninghamella bertholletiae exhibits increased resistance to human neutrophils with or without antifungal agents as compared to Rhizopus spp.

  Medical mycology 20100801

• A multicentre study to evaluate the impact of timing of caspofungin administration on outcomes of invasive candidiasis in non-immunocompromised adult patients.

  The Journal of antimicrobial chemotherapy 20100801

• Generation of mutants in Candida albicans with reduced susceptibility to caspofungin: influence on other antifungal products.

  Journal of chemotherapy (Florence, Italy) 20100801

• Prevalence rates and antifungal susceptibility profiles of the Candida parapsilosis species complex: results from a nationwide surveillance of candidaemia in Brazil.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20100701

• Comparison of antifungal MICs for yeasts obtained using the EUCAST method in a reference laboratory and the Etest in nine different hospital laboratories.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20100701

• Drug interactions and adverse events associated with antimycotic drugs used for invasive aspergillosis in hematopoietic SCT.

  Bone marrow transplantation 20100701

• Caspofungin first-line therapy for invasive aspergillosis in allogeneic hematopoietic stem cell transplant patients: an European Organisation for Research and Treatment of Cancer study.

  Bone marrow transplantation 20100701

• Efficacy of anidulafungin, caspofungin and fluconazole in the early phase of infection in a neutropenic murine invasive candidiasis model.

  International journal of antimicrobial agents 20100701

• Successful topical application of caspofungin in the treatment of fungal keratitis refractory to voriconazole.

  Archives of ophthalmology (Chicago, Ill. : 1960) 20100701

• Phaeohyphomycosis due to Alternaria species in transplant recipients.

  Transplant infectious disease : an official journal of the Transplantation Society 20100601

• Prophylaxis of invasive aspergillosis with voriconazole or caspofungin during building work in patients with acute leukemia.

  Haematologica 20100601

• Caspofungin for post solid organ transplant invasive fungal disease: results of a retrospective observational study.

  Transplant infectious disease : an official journal of the Transplantation Society 20100601

• In vitro combined activity of amphotericin B, caspofungin and voriconazole against clinical isolates of Trichosporon asahii.

  International journal of antimicrobial agents 20100601

• Liposomal amphotericin B eradicates Candida albicans biofilm in a continuous catheter flow model.

  FEMS yeast research 20100601

• Proteomic analysis of proteins released from growth-arrested Candida albicans following exposure to caspofungin.

  Medical mycology 20100601

• Caspofungin-induced severe toxic epidermal necrolysis.

  The Annals of pharmacotherapy 20100601

• Antifungal therapy with itraconazole impairs the anti-lymphoma effects of rituximab by inhibiting recruitment of CD20 to cell surface lipid rafts.

  Cancer research 20100601

• Antifungal activity of amphotericin B, caspofungin and posaconazole on Candida albicans biofilms in intermediate and mature development phases.

  Mycoses 20100501

• Vertebral osteomyelitis due to Aspergillus fumigatus in a patient with chronic granulomatous disease successfully treated with antifungal agents and interferon-gamma.

  Medical mycology 20100501

• Mycotic pulmonary artery aneurysm due to Aspergillus infection in a patient with leukemia: case report and review of the literature.

  Leukemia research 20100501

• Wild-type minimum effective concentration distributions and epidemiologic cutoff values for caspofungin and Aspergillus spp. as determined by Clinical and Laboratory Standards Institute broth microdilution methods.

  Diagnostic microbiology and infectious disease 20100501

• A randomized, double-blind, multicenter study of caspofungin versus liposomal amphotericin B for empiric antifungal therapy in pediatric patients with persistent fever and neutropenia.

  The Pediatric infectious disease journal 20100501

• Traditional and emerging antifungal therapies.

  Proceedings of the American Thoracic Society 20100501

• Sclerosing cholangitis and combination antifungal therapy for PNP deficiency patients.

  European journal of pediatrics 20100401

• Invasive aspergillosis in patients with acute myeloid leukemia: a SEIFEM-2008 registry study.

  Haematologica 20100401

• In vitro activities of eight antifungal drugs against 55 clinical isolates of Fonsecaea spp.

  Antimicrobial agents and chemotherapy 20100401

• Combination of caspofungin or anidulafungin with antimicrobial peptides results in potent synergistic killing of Candida albicans and Candida glabrata in vitro.

  International journal of antimicrobial agents 20100401

• Evaluation of caspofungin or micafungin as empiric antifungal therapy in adult patients with persistent febrile neutropenia: a retrospective, observational, sequential cohort analysis.

  Clinical therapeutics 20100401

• In vivo studies with a Candida tropicalis isolate exhibiting paradoxical growth in vitro in the presence of high concentration of caspofungin.

  Journal of microbiology (Seoul, Korea) 20100401

• [Specific antifungal treatment in patients with neutropenia and fever: current status of the fungicidal activity of caspofungin].

  Drugs of today (Barcelona, Spain : 1998) 20100401

• Splenic hyalohyphomycosis, molecularly and immunologically consistent with invasive aspergillosis, in a patient with acute lymphoblastic leukemia.

  American journal of hematology 20100301

• Caspofungin for the treatment of candidaemia in patients with haematological malignancies.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20100301

• Urban pigeons (Columba livia) as a potential source of pathogenic yeasts: a focus on antifungal susceptibility of Cryptococcus strains in Northeast Brazil.

  Mycopathologia 20100301

• Voriconazole as primary antifungal prophylaxis in patients with neutropenia after hematopoietic stem cell transplantation or chemotherapy for acute myeloid leukemia.

  European journal of haematology 20100301

• The Aspergillus fumigatus P-type Golgi apparatus Ca2+/Mn2+ ATPase PmrA is involved in cation homeostasis and cell wall integrity but is not essential for pathogenesis.

  Eukaryotic cell 20100301

• Successful triple combination therapy of disseminated absidia corymbifera infection in an adolescent with osteosarcoma.

  Journal of pediatric hematology/oncology 20100301

• The impact of delaying the initiation of appropriate antifungal treatment for Candida bloodstream infection.

  Medical mycology 20100301

• Mutants of Candida albicans hypersensitive to calcofluor white display susceptibility to antifungal drugs.

  Folia microbiologica 20100301

• Potential of anti-Candida antibodies in immunoprophylaxis.

  Immunotherapy 20100301

• In vitro activity of antifungal combinations against Candida albicans biofilms.

  The Journal of antimicrobial chemotherapy 20100201

• Activity of aminocandin (IP960; HMR3270) compared with amphotericin B, itraconazole, caspofungin and micafungin in neutropenic murine models of disseminated infection caused by itraconazole-susceptible and -resistant strains of Aspergillus fumigatus.

  International journal of antimicrobial agents 20100201

• Caspofungin-non-susceptible Candida isolates in cancer patients.

  The Journal of antimicrobial chemotherapy 20100201

• The effects of antifungal agents to conidial and hyphal forms of Aspergillus fumigatus.

  Medical mycology 20100201

• Clinical outcomes of lung-transplant recipients treated by voriconazole and caspofungin combination in aspergillosis.

  Journal of clinical pharmacy and therapeutics 20100201

• Echinocandins: A ray of hope in antifungal drug therapy.

  Indian journal of pharmacology 20100201

• [Conservative management with new antifungals in a case of Candida prosthetic valve endocarditis].

  Enfermedades infecciosas y microbiologia clinica 20100101

• Kodamaea ohmeri fungaemia successfully treated with caspofungin.

  International journal of antimicrobial agents 20100101

• The echinocandins: three useful choices or three too many?

  International journal of antimicrobial agents 20100101

• Primary antifungal prophylaxis in acute myeloblastic leukemia and myelodysplastic syndrome--still an open question?

  Leukemia & lymphoma 20100101

• [Successful treatment of catheter-associated candidemia without removing the central venous line].

  Enfermedades infecciosas y microbiologia clinica 20100101

• Caspofungin use in daily clinical practice for treatment of invasive aspergillosis: results of a prospective observational registry.

  BMC infectious diseases 20100101

• [Successful caspofungin treatment of invasive refractory candidiasis in the extremely low birthweight neonate].

  Acta medica portuguesa 20100101

• Lessons from a case of oromandibular mucormycosis treated with surgery and a combination of amphotericin B lipid formulation plus caspofungin.

  Acta haematologica 20100101

• Safety experience with caspofungin in pediatric patients.

  The Pediatric infectious disease journal 20091201

• An EORTC Phase II study of caspofungin as first-line therapy of invasive aspergillosis in haematological patients.

  The Journal of antimicrobial chemotherapy 20091201

• Intraventricular fungus ball: a unique manifestation of refractory intracranial candidiasis in an immunocompetent neonate.

  Journal of neurosurgery. Pediatrics 20091201

• The effects of caspofungin and voriconazole in an experimental fungal infection of the ear due to Aspergillus.

  European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20091101

• High caspofungin levels in alveolar cells of a lung transplant patient with suspected pulmonary aspergillosis.

  International journal of antimicrobial agents 20091101

• Efficacy of caspofungin and itraconazole as secondary antifungal prophylaxis: analysis of data from a multinational case registry.

  International journal of antimicrobial agents 20091101

• Exposure to caspofungin activates Cap and Hog pathways in Candida albicans.

  Medical mycology 20091101

• In vitro analyses of the combination of high-dose doxycycline and antifungal agents against Candida albicans biofilms.

  International journal of antimicrobial agents 20091001

• Intraocular penetration of voriconazole and caspofungin in a patient with fungal endophthalmitis.

  The Journal of antimicrobial chemotherapy 20091001

• Echinocandins: the newest class of antifungals.

  The Annals of pharmacotherapy 20091001

• Hyperbaric oxygen therapy and other adjunctive treatments for zygomycosis.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20091001

• Immediate cross-hypersensitivity between micafungin and caspofungin: a case report.

  Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20090901

• In vitro synergistic effects of antituberculous drugs plus antifungals against Coccidioides posadasii.

  International journal of antimicrobial agents 20090901

• Treatment and prevention of Candida albicans biofilms with caspofungin in a novel central venous catheter murine model of candidiasis.

  The Journal of antimicrobial chemotherapy 20090901

• [Candida albicans endocarditis after pulmonary artery banding].

  Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20090801

• Cost-effectiveness analysis of micafungin versus caspofungin for treatment of systemic Candida infections in the UK.

  Current medical research and opinion 20090801

• Generation of resistance to amphotericin B and caspofungin in Candida spp.: experimental study.

  Journal of chemotherapy (Florence, Italy) 20090801

• Caspofungin: new indication. Same indications in children as in adults.

  Prescrire international 20090801

• An early CT-diagnosis-based treatment strategy for invasive fungal infection in allogeneic transplant recipients using caspofungin first line: an effective strategy with low mortality.

  Bone marrow transplantation 20090701

• Monotherapy with caspofungin for candidaemia in adult patients with cancer: a retrospective, single institution study.

  International journal of antimicrobial agents 20090701

• [Successful treatment of neuroaspergillosis in a patient with acute lymphoblastic leukemia: role of surgery, systemic antifungal therapy and intracavitary therapy].

  Mikrobiyoloji bulteni 20090701

• A Multicenter, double-blind trial of a high-dose caspofungin treatment regimen versus a standard caspofungin treatment regimen for adult patients with invasive candidiasis.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090615

• Frequency of paradoxical effect with caspofungin in Candida albicans.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20090601

• In vitro activity of caspofungin and voriconazole against uncommon Candida spp.

  International journal of antimicrobial agents 20090601

• Economic impact of caspofungin as compared with liposomal amphotericin B for empirical therapy in febrile neutropenia in Australia.

  The Journal of antimicrobial chemotherapy 20090601

• Infections caused by Candida krusei in five transplant and two surgical patients.

  Surgical infections 20090601

• Breakthrough rhinocerebral mucormycosis in a liver transplant patient receiving caspofungin.

  Transplantation proceedings 20090601

• Caspofungin for prevention of intra-abdominal candidiasis in high-risk surgical patients.

  Intensive care medicine 20090501

• Neonatal liver abscesses due to Candida infection effectively treated with caspofungin.

  Acta paediatrica (Oslo, Norway : 1992) 20090501

• Successful treatment with caspofungin of refractory Candida krusei candidemia in a very low birth weight preterm infant.

  The Pediatric infectious disease journal 20090501

• Diagnosis and treatment of aspergillosis in children.

  Expert review of anti-infective therapy 20090501

• Candida infective endocarditis: report of 15 cases from a prospective multicenter study.

  Medicine 20090501

• [Argument against the article entitled Caspofungin treatment of a premature infant with mould septicemia].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20090501

• Caspofungin in salvage treatment of severe pneumocystis pneumonia: case report and literature review.

  Chinese medical journal 20090420

• Alternaria infectoria brain abscess in a child with chronic granulomatous disease.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20090401

• Is Candida colonization of central vascular catheters in non-candidemic, non-neutropenic patients an indication for antifungals?

  Intensive care medicine 20090401

• Pharmacokinetics of caspofungin and voriconazole in critically ill patients during extracorporeal membrane oxygenation.

  The Journal of antimicrobial chemotherapy 20090401

• Successful intensive chemotherapy followed by autologous hematopoietic cell transplantation in a patient with acute myeloid leukemia and hepatosplenic candidiasis: case report and review of literature.

  Transplant infectious disease : an official journal of the Transplantation Society 20090401

• Compassionate use study of caspofungin in children with proven or suspected invasive mycosis or persistent febrile neutropenia.

  Journal of chemotherapy (Florence, Italy) 20090401

• Combined antifungal therapy for persistent central venous catheter-related candidemia in extremely low birth weight neonates.

  Journal of chemotherapy (Florence, Italy) 20090401

• Breakthrough Fusarium spp fungemia during caspofungin therapy in an ABO-incompatible orthotopic liver transplant patient.

  Journal of chemotherapy (Florence, Italy) 20090401

• [Clinical use of micafungin for the treatment of invasive candidiasis in critical ill patients].

  Revista iberoamericana de micologia 20090331

• [Micafungin in invasive candidiasis among oncohematological patients].

  Revista iberoamericana de micologia 20090331

• Susceptibility of Candida albicans to common and novel antifungal drugs, and relationship between the mating type locus and resistance, in Lebanese hospital isolates.

  Mycoses 20090301

• Differential in vitro activity of anidulafungin, caspofungin and micafungin against Candida parapsilosis isolates recovered from a burn unit.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20090301

• [Invasive pulmonary aspergillosis. Occurrence in a non-neutropenic female patient with abdominal sepsis].

  Der Anaesthesist 20090301

• A prospective, multicenter study of caspofungin for the treatment of documented Candida or Aspergillus infections in pediatric patients.

  Pediatrics 20090301

• [Cerebral aspergillosis in an HIV-infected patient: unsuccessful outcome despite combined antifungal therapy. ].

  Enfermedades infecciosas y microbiologia clinica 20090301

• Proteomic and phenotypic profiling of the amphibian pathogen Batrachochytrium dendrobatidis shows that genotype is linked to virulence.

  Molecular ecology 20090201

• Aspergillus flavus sinusitis in ALL.

  American journal of hematology 20090201

• Difference in killing activity of caspofungin and paradoxical growth between Candida albicans and C. krusei clinical isolates in different media.

  Journal of chemotherapy (Florence, Italy) 20090201

• Breakthrough Candida dubliniensis fungemia in an acute myeloid leukemia patient during voriconazole therapy successfully treated with caspofungin.

  Journal of chemotherapy (Florence, Italy) 20090201

• Oesophageal aspergillosis in a case of acute lymphoblastic leukaemia successfully treated with caspofungin alone due to liposomal amphotericin B induced severe hepatotoxicity.

  Mycoses 20090101

• Candida endocarditis: role of new antifungal agents.

  Mycoses 20090101

• Successful treatment of Candida spp. encephalitis occurring under Caspofungin treatment after allogeneic stem cell transplantation.

  Annals of hematology 20090101

• In vitro synergy of caspofungin with licensed and novel antifungal drugs against clinical isolates of Fusarium spp.

  Medical mycology 20090101

• The echinocandin caspofungin impairs the innate immune mechanism against Candida parapsilosis.

  International journal of antimicrobial agents 20090101

• Potential voriconazole and caspofungin sequestration during extracorporeal membrane oxygenation.

  Intensive care medicine 20090101

• Alternaria keratitis: clinical presentation and resolution with topical fluconazole or intrastromal voriconazole and topical caspofungin.

  Cornea 20090101

• Aqueous humor concentrations of topically administered caspofungin in rabbits.

  Ophthalmic research 20090101

• Combined therapy with amphotericin B and caspofungin in an experimental model of disseminated histoplasmosis.

  Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20090101

• Caspofungin: in pediatric patients with fungal infections.

  Paediatric drugs 20090101

• Invasive Aspergillus fumigatus infection after Plasmodium falciparum malaria in an immuno-competent host: case report and review of literature.

  Malaria journal 20090101

• Successful treatment of Candida albicans septicemia in a preterm infant with severe congenital ichthyosis (Harlequin baby).

  Pediatric dermatology 20090101

• Economic evaluation of voriconazole versus caspofungin for the treatment of invasive aspergillosis in Belgium.

  Acta clinica Belgica 20090101

• A 6-year-old boy with fever and eosinophilia.

  Allergy and asthma proceedings 20090101

• [Azole-resistant invasive aspergillosis].

  Nederlands tijdschrift voor geneeskunde 20090101

• Anticandidal effects of voriconazole and caspofungin, singly and in combination, against Candida glabrata, extracellularly and intracellularly in granulocyte-macrophage colony stimulating factor (GM-CSF)-activated human monocytes.

  The Journal of antimicrobial chemotherapy 20081201

• Phase-dependent antifungal activity against Aspergillus fumigatus developing multicellular filamentous biofilms.

  The Journal of antimicrobial chemotherapy 20081201

• Comparison of killing activity of caspofungin against Candida parapsilosis, Candida orthopsilosis and Candida metapsilosis.

  The Journal of antimicrobial chemotherapy 20081201

• Membrane-filter bubble-point test.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20081201

• Caspofungin for the treatment of pediatric fungal infections.

  The Pediatric infectious disease journal 20081201

• Dynamic, morphotype-specific Candida albicans beta-glucan exposure during infection and drug treatment.

  PLoS pathogens 20081201

• [Trends in development of new antifungal agents in Japan].

  Nihon rinsho. Japanese journal of clinical medicine 20081201

• [In vitro activity of anidulafungin. Comparison with the activity of other echinocandins].

  Enfermedades infecciosas y microbiologia clinica 20081201

• [Pharmacokinetics and pharmacodynamics: interactions and adverse effects. Comparison with other echinocandins].

  Enfermedades infecciosas y microbiologia clinica 20081201

• Invasive aspergillosis in paediatric oncology patients.

  The Medical journal of Malaysia 20081201

• A clinical cohort trial of antifungal combination therapy: efficacy and toxicity in haematological cancer patients.

  Annals of hematology 20081101

• Evaluation of aminocandin and caspofungin against Candida glabrata including isolates with reduced caspofungin susceptibility.

  The Journal of antimicrobial chemotherapy 20081101

• In vitro susceptibility of Pythium insidiosum and a Lagenidium sp to itraconazole, posaconazole, voriconazole, terbinafine, caspofungin, and mefenoxam.

  American journal of veterinary research 20081101

• Acute refractory hyperkalaemia and fatal cardiac arrest related to administration of liposomal amphotericin B.

  The Netherlands journal of medicine 20081101

• Caspofungin.

  Indian pediatrics 20081101

• Efalizumab treatment associated with Candida colitis.

  Journal of the American Academy of Dermatology 20081101

• Double-blind active-control trials: beware the comparator you keep.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20081015

• Subculture on potato dextrose agar as a complement to the broth microdilution assay for Malassezia pachydermatis.

  Journal of microbiological methods 20081001

• Functional analysis of Candida albicans GPI-anchored proteins: roles in cell wall integrity and caspofungin sensitivity.

  Fungal genetics and biology : FG & B 20081001

• [Tolerance of caspofungin in intensive care unit: a prospective study].

  Annales francaises d'anesthesie et de reanimation 20081001

• Chronic necrotizing and allergic bronchopulmonary aspergillosis in an asthmatic patient--a therapeutic challenge.

  The clinical respiratory journal 20081001

• Disseminated aspergillosis in an adolescent with acute lymphoblastic leukemia.

  Pediatric blood & cancer 20080901

• Antifungal activity against Candida albicans of nikkomycin Z in combination with caspofungin, voriconazole or amphotericin B.

  The Journal of antimicrobial chemotherapy 20080901

• Significant differences in drug susceptibility among species in the Candida parapsilosis group.

  Diagnostic microbiology and infectious disease 20080901

• Trends in species distribution and susceptibility of bloodstream isolates of Candida collected in Monterrey, Mexico, to seven antifungal agents: results of a 3-year (2004 to 2007) surveillance study.

  Journal of clinical microbiology 20080901

• Treatment of invasive candidal infections: systematic review and meta-analysis.

  Mayo Clinic proceedings 20080901

• Seven-year trend analysis of nosocomial candidemia and antifungal (fluconazole and caspofungin) use in Intensive Care Units at a Brazilian University Hospital.

  Medical mycology 20080901

• Efficacy and safety of caspofungin therapy in elderly patients with proven or suspected invasive fungal infections.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20080801

• In vitro susceptibilities of invasive isolates of Candida species: rapid increase in rates of fluconazole susceptible-dose dependent Candida glabrata isolates.

  Antimicrobial agents and chemotherapy 20080801

• Combination polyene-caspofungin treatment of rhino-orbital-cerebral mucormycosis.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080801

• Effective management of pulmonary aspergillosis invading the thoracic spine in a child with high risk ALL requiring allogeneic bone marrow transplantation.

  Medical mycology 20080801

• Caspofungin modulates inflammatory responses to Aspergillus fumigatus through stage-specific effects on fungal beta-glucan exposure.

  The Journal of infectious diseases 20080715

• Caspofungin-mediated beta-glucan unmasking and enhancement of human polymorphonuclear neutrophil activity against Aspergillus and non-Aspergillus hyphae.

  The Journal of infectious diseases 20080715

• Time-kill studies investigating the killing activity of caspofungin against Candida dubliniensis: comparing RPMI-1640 and antibiotic medium 3.

  The Journal of antimicrobial chemotherapy 20080701

• In vitro efficacies of caspofungin or micafungin catheter lock solutions on Candida albicans biofilm growth.

  The Journal of antimicrobial chemotherapy 20080701

• Treatment of a critically ill child with disseminated Candida glabrata with a recombinant human antibody specific for fungal heat shock protein 90 and liposomal amphotericin B, caspofungin, and voriconazole.

  Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20080701

• Caspofungin-resistant Aspergillus flavus after heart transplantation and mechanical circulatory support: a case report.

  Transplant infectious disease : an official journal of the Transplantation Society 20080601

• Therapeutic and prophylactic efficacy of aminocandin (IP960) against disseminated candidiasis in mice.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20080601

• [Treatment of fungal septicemia in a premature infant with caspofungin].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20080601

• Invasive pulmonary infection due to Trichoderma longibrachiatum mimicking invasive Aspergillosis in a neutropenic patient successfully treated with voriconazole combined with caspofungin.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080515

• Efungumab and caspofungin: pre-clinical data supporting synergy.

  The Journal of antimicrobial chemotherapy 20080501

• Comparison of the dose-dependent activity and paradoxical effect of caspofungin and micafungin in a neutropenic murine model of invasive pulmonary aspergillosis.

  The Journal of antimicrobial chemotherapy 20080501

• Successful treatment of disseminated Geotrichum capitatum infection with a combination of caspofungin and voriconazole in an immunocompromised patient.

  Mycoses 20080501

• Characterization of caspofungin susceptibilities by broth and agar in Candida albicans clinical isolates with characterized mechanisms of azole resistance.

  Medical mycology 20080501

• New options for treatment of candidaemia in critically ill patients.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20080501

• Comparison of the efficacy of combination and monotherapy with caspofungin and liposomal amphotericin B against invasive candidiasis.

  Saudi medical journal 20080501

• Defining targets for investigating the pharmacogenomics of adverse drug reactions to antifungal agents.

  Pharmacogenomics 20080501

• Economic evaluation of caspofungin vs liposomal amphotericin B for empirical therapy of suspected systemic fungal infection in the German hospital setting.

  Annals of hematology 20080401

• Fluvastatin potentiates the activity of caspofungin against Aspergillus fumigatus in vitro.

  Diagnostic microbiology and infectious disease 20080401

• Multilaboratory testing of antifungal combinations against a quality control isolate of Candida krusei.

  Antimicrobial agents and chemotherapy 20080401

• Successful treatment of prosthetic knee Candida glabrata infection with caspofungin combined with flucytosine.

  International journal of antimicrobial agents 20080401

• Breakthrough C. parapsilosis and C. guilliermondii blood stream infections in allogeneic hematopoietic stem cell transplant recipients receiving long-term caspofungin therapy.

  Haematologica 20080401

• Acute monoblastic leukemia with t(10;11)(p12;q23) presenting with pulmonary involvement: a case report and literature review.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20080401

• Comparison of microdilution method and E-test procedure in susceptibility testing of caspofungin against Candida non-albicans species.

  The new microbiologica 20080401

• Novel antifungal agents as salvage therapy for invasive aspergillosis in patients with hematologic malignancies: posaconazole compared with high-dose lipid formulations of amphotericin B alone or in combination with caspofungin.

  Leukemia 20080301

• Visual compatibility of caspofungin acetate with commonly used drugs during simulated Y-site delivery.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080301

• [Cutaneous, pulmonary and bone aspergillosis in a patient presumed immunocompetent presenting subacute cutaneous lupus erythematosus].

  Annales de dermatologie et de venereologie 20080301

• Points of concern related to the micafungin versus caspofungin trial.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080215

• Candida krusei--a serious complication in patients with hematological malignancies: successful treatment with caspofungin.

  Transplant infectious disease : an official journal of the Transplantation Society 20080201

• Successfully treated Candida krusei infection of the lumbar spine with combined caspofungin/posaconazole therapy.

  Medical mycology 20080201

• Breakthrough Trichosporon asahii fungemia in neutropenic patient with acute leukemia while receiving caspofungin.

  Infection 20080201

• Combined voriconazole plus caspofungin therapy for the treatment of probable Geotrichum pneumonia in a leukemia patient.

  Infection 20080201

• Posaconazole activity against Candida glabrata after exposure to caspofungin or amphotericin B.

  Antimicrobial agents and chemotherapy 20080201

• Paradoxical growth effects of the echinocandins caspofungin and micafungin, but not of anidulafungin, on clinical isolates of Candida albicans and C. dubliniensis.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20080201

• Increasing incidence of Candida parapsilosis candidemia with caspofungin usage.

  The Journal of infection 20080201

• Candida dubliniensis meningitis as delayed sequela of treated C. dubliniensis fungemia.

  Emerging infectious diseases 20080201

• [Antifungal activity of posaconazole and caspofungin in yeast causing invasive fungal infection (2002-2003). E-test system evaluation].

  Enfermedades infecciosas y microbiologia clinica 20080201

• Invasive pulmonary aspergillosis after liver transplantation: rapid and complete response to combined and sequential antifungal therapy.

  Surgical infections 20080201

• Multifocal Scedosporium apiospermum spondylitis in a cystic fibrosis patient.

  Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 20080101

• Emergence of Candida tropicalis resistant to caspofungin.

  The Journal of antimicrobial chemotherapy 20080101

• Activity of caspofungin and voriconazole against clinical isolates of Candida and other medically important yeasts by the CLSI M-44A disk diffusion method with Neo-Sensitabs tablets.

  Chemotherapy 20080101

• Caspofungin as first-line therapy for the treatment of invasive aspergillosis after thoracic organ transplantation.

  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080101

• Successful treatment of invasive Aspergillus sinusitis with caspofungin and voriconazole.

  Ear, nose, & throat journal 20080101

• Saccharomyces boulardii fungaemia in an intensive care unit patient treated with caspofungin.

  Critical care (London, England) 20080101

• Developments in the epidemiolgy of invasive fungal infections - implications for the empiric and targeted antifungal therapy.

  Mycoses 20080101

• Comedication of caspofungin acetate and cyclosporine A after allogeneic haematopoietic stem cell transplantation leads to negligible hepatotoxicity.

  Mycoses 20080101

• Efficacy of caspofungin in invasive candidiasis and candidemia--de-escalation strategy.

  Mycoses 20080101

• Caspofungin for treatment of invasive aspergillus infections.

  Mycoses 20080101

• Experiences with the use of caspofungin in paediatric patients.

  Mycoses 20080101

• Pneumocystis jiroveci pneumonia in a patient with Wegener's granulomatosis treated efficiently with caspofungin.

  Mycoses 20080101

• Economic evaluation of caspofungin versus liposomal amphotericin B for empiric antifungal treatment in patients with neutropenic fever in Italy.

  Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20080101

• Hospital-acquired invasive pulmonary aspergillosis in patients with hepatic failure.

  BMC gastroenterology 20080101

• Antifungal susceptibility of 95 yeast strains isolated from oral mycoses in HIV-negative and HIV-positive patients.

  Bacteriologia, virusologia, parazitologia, epidemiologia (Bucharest, Romania : 1990) 20080101

• Liposomal amphotericin B in combination with caspofungin for invasive aspergillosis in patients with hematologic malignancies: a randomized pilot study (Combistrat trial).

  Cancer 20071215

• Efficacy of caspofungin and posaconazole in a murine model of disseminated Exophiala infection.

  Medical mycology 20071201

• Caspofungin reduces the incidence of fungal contamination in cell culture.

  Mycopathologia 20071201

• Therapeutic efficacy of caspofungin alone and in combination with amphotericin B deoxycholate for coccidioidomycosis in a mouse model.

  The Journal of antimicrobial chemotherapy 20071201

• Breakthrough invasive aspergillosis in allogeneic haematopoietic stem cell transplant recipients treated with caspofungin.

  International journal of antimicrobial agents 20071201

• Caspofungin as primary antifungal prophylaxis in stem cell transplant recipients.

  Pharmacotherapy 20071201

• Efficacy and safety of caspofungin in solid organ transplant recipients.

  Transplantation proceedings 20071201

• [The fungicidal activity and paradoxical effect of caspofungin against yeast. Influence of culture medium and incubation time].

  Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20071201

• Survival in the presence of antifungals: genome-wide expression profiling of Aspergillus niger in response to sublethal concentrations of caspofungin and fenpropimorph.

  The Journal of biological chemistry 20071109

• Lethal double infection with Acremonium strictum and Aspergillus fumigatus during induction chemotherapy in a child with ALL.

  Pediatric blood & cancer 20071101

• Caspofungin in vitro and in vivo activity against Brazilian Pythium insidiosum strains isolated from animals.

  The Journal of antimicrobial chemotherapy 20071101

• Requirement for Candida albicans Sun41 in biofilm formation and virulence.

  Eukaryotic cell 20071101

• Disseminated invasive aspergillosis with cerebral involvement successfully treated with caspofungin and voriconazole.

  Infection 20071001

• Candidemia-induced acute interstitial nephritis.

  Nephrology (Carlton, Vic.) 20071001

• Micafungin versus caspofungin for treatment of candidemia and other forms of invasive candidiasis.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20071001

• Efficacy of caspofungin addition to trimethoprim-sulfamethoxazole treatment for severe pneumocystis pneumonia in solid organ transplant recipients.

  Transplantation 20070927

• Successful treatment of refractory chronic disseminated candidiasis after prolonged administration of caspofungin in a child with acute myeloid leukemia.

  Pediatric blood & cancer 20070901

• Successful treatment of invasive candidiasis with caspofungin in a child with acute lymphoblastic leukemia.

  Pediatric blood & cancer 20070901

• Synergistic effect of posaconazole and caspofungin against clinical zygomycetes.

  Antimicrobial agents and chemotherapy 20070901

• Efficacy and safety of caspofungin for the empiric management of fever in neutropenic children.

  The Pediatric infectious disease journal 20070901

• Invasive candidiasis treated in the intensive care unit: observations from a randomized clinical trial.

  Journal of critical care 20070901

• In vitro activities of voriconazole as a triazole derivative and caspofungin as an echinocandin were compared with those of some antifungal agents against Candida species isolated from clinical specimens.

  Japanese journal of infectious diseases 20070901

• Triple antifungal therapy for severe systemic candidiasis allowed performance of allogeneic stem cell transplantation.

  European journal of medical research 20070816

• Caspofungin for the treatment of less common forms of invasive candidiasis.

  The Journal of antimicrobial chemotherapy 20070801

• Efficacy of caspofungin as secondary prophylaxis in patients undergoing allogeneic stem cell transplantation with prior pulmonary and/or systemic fungal infection.

  Bone marrow transplantation 20070801

• Economic evaluation of targeted treatments of invasive aspergillosis in adult haematopoietic stem cell transplant recipients in the Netherlands: a modelling approach.

  The Journal of antimicrobial chemotherapy 20070801

• Single- and multiple-dose administration of caspofungin in patients with hepatic insufficiency: implications for safety and dosing recommendations.

  Journal of clinical pharmacology 20070801

• Assessing the antifungal activity, pharmacokinetics, and tissue distribution of amphotericin B following the administration of Abelcet and AmBisome in combination with caspofungin to rats infected with Aspergillus fumigatus.

  Journal of pharmaceutical sciences 20070701

• In vitro susceptibilities of 217 clinical isolates of zygomycetes to conventional and new antifungal agents.

  Antimicrobial agents and chemotherapy 20070701

• Factors influencing caspofungin plasma concentrations in patients of a surgical intensive care unit.

  The Journal of antimicrobial chemotherapy 20070701

• Efficacy of topical caspofungin in experimental fusarium keratitis.

  Cornea 20070701

• Basidiomycetous fungal Inonotus tropicalis sacral osteomyelitis in X-linked chronic granulomatous disease.

  The Pediatric infectious disease journal 20070701

• A comparative evaluation of properties and clinical efficacy of the echinocandins.

  Expert opinion on pharmacotherapy 20070701

• Ocular penetration of caspofungin in a rabbit uveitis model.

  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20070601

• A retrospective nationwide case study on the use of a new antifungal agent: patients treated with caspofungin during 2001-2004 in Finland.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20070601

• A cost-effectiveness analysis of caspofungin vs. liposomal amphotericin B for treatment of suspected fungal infections in the UK.

  European journal of haematology 20070601

• Multicenter evaluation of a new disk agar diffusion method for susceptibility testing of filamentous fungi with voriconazole, posaconazole, itraconazole, amphotericin B, and caspofungin.

  Journal of clinical microbiology 20070601

• Successful management of Aspergillus liver abscess in a patient with necrotizing fasciitis.

  Digestive diseases and sciences 20070601

• Acquired resistance to echinocandins in Candida albicans: case report and review.

  The Journal of antimicrobial chemotherapy 20070601

• The use of caspofungin in HIV-infected individuals.

  Expert opinion on investigational drugs 20070601

• A colorimetric and spectrophotometric method for in vitro susceptibility testing of Aspergillus species against caspofungin.

  Medical mycology 20070601

• Diagnostic and therapeutic challenge of Aspergillus flavus scleritis.

  Cornea 20070601

• Secular trends in severe renal failure associated with the use of new antimicrobial agents in critically ill surgical patients.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20070601

• Antimicrobial susceptibility of Fusarium, Aspergillus, and other filamentous fungi isolated from keratitis.

  Archives of ophthalmology (Chicago, Ill. : 1960) 20070601

• In vitro activity of fluconazole, voriconazole and caspofungin against clinical yeast isolates.

  Journal of chemotherapy (Florence, Italy) 20070601

• Persistence of Candida albicans candidemia in non-neutropenic surgical patients: management of a representative patient in the absence of second-line treatment guidelines.

  Journal of chemotherapy (Florence, Italy) 20070601

• Nebulized liposomal amphotericin B and combined systemic antifungal therapy for the treatment of severe pulmonary aspergillosis after allogeneic hematopoietic stem cell transplant for a fatal mitochondrial disorder.

  Journal of chemotherapy (Florence, Italy) 20070601

• [Native valve Aspergillus fumigatus endocarditis with blood culture positive and negative for galactomannan antigen. Case report and literature review].

  Revista iberoamericana de micologia 20070601

• Caspofungin in kidney transplant recipients with refractory invasive candidiasis.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501

• Liquid chromatography-mass spectrometry method for quantification of caspofungin in clinical plasma samples.

  Journal of mass spectrometry : JMS 20070401

• The pharmacology and clinical use of caspofungin.

  Expert opinion on drug metabolism & toxicology 20070401

• [Biofilm production and antifungal susceptibility patterns of Candida species isolated from hospitalized patients].

  Mikrobiyoloji bulteni 20070401

• [Comparison of minimum inhibitory and minimum effective concentration values for the detection of in vitro susceptibilities of Aspergillus species against caspofungin].

  Mikrobiyoloji bulteni 20070401

• [Intracranial aspergillosis in an immunocompetent patient].

  Mikrobiyoloji bulteni 20070401

• Synthesis of the antifungal beta-1,3-glucan synthase inhibitor CANCIDAS (caspofungin acetate) from pneumocandin B0.

  The Journal of organic chemistry 20070330

• Pharmacoeconomic analysis of caspofungin versus liposomal amphotericin B as empirical antifungal therapy for neutropenic fever.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070315

• Autologous transplantation of CD133 selected hematopoietic progenitor cells for treatment of relapsed acute lymphoblastic leukemia.

  Pediatric blood & cancer 20070301

• In vitro biofilm characterization and activity of antifungal agents alone and in combination against sessile and planktonic clinical Candida albicans isolates.

  Diagnostic microbiology and infectious disease 20070301

• Caspofungin in the treatment of symptomatic candiduria.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070301

• When a paradoxical increase in serum galactomannan antigen during caspofungin therapy is not paradoxical after all.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070301

• The echinocandins.

  Pharmacotherapy 20070301

• Induction of a high affinity fibronectin receptor in Candida albicans by caspofungin: requirements for beta (1,6) glucans and the developmental regulator Hbr1p.

  Medical mycology 20070301

• Caspofungin for the treatment of fungal infections: a systematic review of randomized controlled trials.

  International journal of antimicrobial agents 20070201

• High-dose caspofungin combination antifungal therapy in patients with hematologic malignancies and hematopoietic stem cell transplantation.

  Bone marrow transplantation 20070201

• Caspofungin for the treatment of azole resistant candidemia in a premature infant.

  Journal of perinatology : official journal of the California Perinatal Association 20070201

• Candida inferior vena cava filter infection and septic thrombophlebitis.

  The British journal of radiology 20070201

• Caspofungin-resistant oral and esophageal candidiasis in a patient with AIDS.

  AIDS (London, England) 20070102

• Effect of caspofungin on trophozoites and cysts of three species of Acanthamoeba.

  The Journal of antimicrobial chemotherapy 20070101

• Invasive esophageal aspergillosis associated with acute myelogenous leukemia: successful therapy with combination caspofungin and liposomal amphotericin B.

  Pediatric hematology and oncology 20070101

• Cerebral aspergillosis diagnosed by detection of Aspergillus flavus-specific DNA, galactomannan and (1-->3)-beta-D-glucan in clinical specimens.

  Journal of medical microbiology 20070101

• Susceptibility of environmental versus clinical strains of pathogenic Aspergillus.

  International journal of antimicrobial agents 20070101

• Economic evaluation of voriconazole versus caspofungin for the treatment of invasive aspergillosis in Spain.

  Clinical drug investigation 20070101

• The effects of caspofungin and voriconazole in experimental Candida endophthalmitis.

  Current eye research 20070101

• Caspofungin as salvage monotherapy for invasive aspergillosis in patients with haematological malignancies or following allogeneic stem cell transplantation: efficacy and concomitant cyclosporin A.

  Mycoses 20070101

• Safety and efficacy of a caspofungin-based combination therapy for treatment of proven or probable aspergillosis in pediatric hematological patients.

  BMC infectious diseases 20070101

• Resolution of disseminated fusariosis in a child with acute leukemia treated with combined antifungal therapy: a case report.

  BMC infectious diseases 20070101

• Treatment of two postoperative endophthalmitis cases due to Aspergillus flavus and Scopulariopsis spp. with local and systemic antifungal therapy.

  BMC infectious diseases 20070101

• Voriconazole in the treatment of invasive aspergillosis in kidney transplant recipients.

  Transplantation proceedings 20070101

• Adjuvant endobronchial amphotericin B for refractory invasive pulmonary aspergillosis: evidence is scarce but promise does exist.

  Respiration; international review of thoracic diseases 20070101

• Multicenter, noncomparative study of caspofungin in combination with other antifungals as salvage therapy in adults with invasive aspergillosis.

  Cancer 20061215

• [Successful treatment with caspofungin of an invasive candidosis resistant to liposomal amphotericin B in a neutropenic patient].

  Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20061201

• Antifungal interactions within the triple combination of amphotericin B, caspofungin and voriconazole against Aspergillus species.

  The Journal of antimicrobial chemotherapy 20061201

• Comparative in vivo activity of BAL4815, the active component of the prodrug BAL8557, in a neutropenic murine model of disseminated Aspergillus flavus.

  The Journal of antimicrobial chemotherapy 20061201

• Efficacy and safety of caspofungin therapy in children with invasive fungal infections.

  The Pediatric infectious disease journal 20061201

• Safety profile of concomitant use of caspofungin and cyclosporine or tacrolimus in liver transplant patients.

  Infection 20061201

• Development of candidemia on caspofungin therapy: a case report.

  Infection 20061201

• Efficacies of caspofungin and a combination of caspofungin and meropenem in the treatment of murine disseminated candidiasis.

  APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20061201

• Caspofungin: a major breakthrough in treatment of systemic fungal infections.

  The Journal of the Association of Physicians of India 20061201

• Antifungal alternatives for invasive candidiasis refractory to caspofungin in liver transplant recipients: A report of two cases.

  Transplantation 20061127

• Unexplained increase in Paecilomyces variotii blood culture isolates in the UK.

  Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20061116

• Development of a high-performance liquid chromatography method for the determination of caspofungin with amperometric detection and its application to in vitro microdialysis experiments.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061107

• Comparison of antifungal treatments for murine fusariosis.

  The Journal of antimicrobial chemotherapy 20061101

• Multi-azole resistance in Aspergillus fumigatus.

  International journal of antimicrobial agents 20061101

• Caspofungin for invasive candidiasis at a tertiary care medical center.

  The American journal of medicine 20061101

• Successful treatment of Candida krusei fungemia with amphotericin B and caspofungin.

  Medical mycology 20061101

• Comparison of susceptibility and transcription profile of the new antifungal hassallidin A with caspofungin.

  Biochemical and biophysical research communications 20061020

• Clinical research in the lay press: irresponsible journalism raises a huge dose of doubt.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20061015

• New agents for the treatment of fungal infections: clinical efficacy and gaps in coverage.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20061015

• Antifungal therapy in patients with hematological malignancies: how to avoid overtreatment?

  European journal of haematology 20061001

• Echinocandins in the management of invasive fungal infections, Part 2.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20061001

• An open study of the comparative efficacy and safety of caspofungin and liposomal amphotericin B in treating invasive fungal infections or febrile neutropenia in patients with haematological malignancy.

  Journal of medical microbiology 20061001

• Clinical efficacy and tolerability of caspofungin in a renal transplant patient with Aspergillus flavus lung infection: case report.

  Journal of chemotherapy (Florence, Italy) 20061001

• Epidemiology and outcome of Rhodotorula fungemia in a tertiary care hospital.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060915

• Echinocandins for candidemia in adults without neutropenia.

  The New England journal of medicine 20060914

• Evaluation of caspofungin and amphotericin B deoxycholate against Candida albicans biofilms in an experimental intravascular catheter infection model.

  The Journal of infectious diseases 20060901

• Voriconazole brain tissue levels in rhinocerebral aspergillosis in a successfully treated young woman.

  International journal of antimicrobial agents 20060901

• Successful initial treatment with caspofungin alone for hepatosplenic candidiasis in a patient with acute myeloblastic leukemia.

  Saudi medical journal 20060901

• Trichosporon asahii. Blood-stream infection in a non-cancer patient receiving combination antifungal therapy.

  The Ulster medical journal 20060901

• Efficacy of amphotericin B or amphotericin B-intralipid in combination with caspofungin against experimental aspergillosis.

  The Journal of infection 20060801

• Unclear fever 7 weeks after renal transplantation in a 56-year-old patient.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060801

• Caspofungin activity against clinical isolates of azole cross-resistant Candida glabrata overexpressing efflux pump genes.

  The Journal of antimicrobial chemotherapy 20060801

• Paradoxical increase in circulating Aspergillus antigen during treatment with caspofungin in a patient with pulmonary aspergillosis.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060801

• Specific antibody to Cryptococcus neoformans glucurunoxylomannan antagonizes antifungal drug action against cryptococcal biofilms in vitro.

  The Journal of infectious diseases 20060715

• Candida albicans endocarditis treatment with caspofungin in an HIV-infected patient--case report and review of literature.

  The Journal of infection 20060701

• Interaction between posaconazole and caspofungin in concomitant treatment of mice with systemic Aspergillus infection.

  Antimicrobial agents and chemotherapy 20060701

• Disruption of the Aspergillus fumigatus ECM33 homologue results in rapid conidial germination, antifungal resistance and hypervirulence.

  Microbiology (Reading, England) 20060701

• FsFKS1, the 1,3-beta-glucan synthase from the caspofungin-resistant fungus Fusarium solani.

  Eukaryotic cell 20060701

• [The treatment of pneumocystis Carinii pneumonia with caspofungin in elderly patients: a case report and literature review].

  Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20060701

• Caspofungin: an advanced treatment approach for suspected or confirmed invasive aspergillosis.

  International journal of antimicrobial agents 20060601

• Antifungal combination treatment: a future perspective.

  International journal of antimicrobial agents 20060601

• Progressive esophagitis caused by Candida albicans with reduced susceptibility to caspofungin.

  Pharmacotherapy 20060601

• In vitro activities of 10 combinations of antifungal agents against the multiresistant pathogen Scopulariopsis brevicaulis.

  Antimicrobial agents and chemotherapy 20060601

• A case of pulmonary aspergillosis with lack of response to caspofungin.

  Revista iberoamericana de micologia 20060601

• Modern antifungal therapy for neutropenic fever.

  Current hematologic malignancy reports 20060601

• Possible hepatosplenic candidiasis treated with liposomal amphotericin B and caspofungin combination.

  The Journal of infection 20060501

• Emerging echinocandins for treatment of invasive fungal infections.

  Expert opinion on emerging drugs 20060501

• Successful caspofungin treatment of multidrug resistant Candida parapsilosis septicaemia in an extremely low birth weight neonate.

  Mycoses 20060501

• Caspofungin in the treatment of azole-refractory esophageal candidiasis in kidney transplant recipients.

  Transplantation proceedings 20060501

• Successful treatment of Candida tropicalis arthritis, osteomyelitis and costochondritis with caspofungin and fluconazole in a recipient of bone marrow transplantation.

  Acta paediatrica (Oslo, Norway : 1992) 20060501

• Caspofungin: antifungal activity in vitro, pharmacokinetics, and effects on fungal load and animal survival in neutropenic rats with invasive pulmonary aspergillosis.

  The Journal of antimicrobial chemotherapy 20060401

• Cost savings with implementation of PNA FISH testing for identification of Candida albicans in blood cultures.

  Diagnostic microbiology and infectious disease 20060401

• Amphotericin B and caspofungin resistance in Candida glabrata isolates recovered from a critically ill patient.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060401

• Echinocandin antifungals: review and update.

  Expert review of anti-infective therapy 20060401

• Successful treatment of liposomal amphotericin B refractory Candida glabrata fungaemia in a patient undergoing a stem cell transplantation.

  The Netherlands journal of medicine 20060401

• Trichosporon asahii fungemia in a patient with non-hematological malignancy.

  Japanese journal of infectious diseases 20060401

• A drug-sensitive genetic network masks fungi from the immune system.

  PLoS pathogens 20060401

• Treatment with caspofungin in immunocompromised paediatric patients: a multicentre survey.

  The Journal of antimicrobial chemotherapy 20060301

• Head-to-head comparison of the activities of currently available antifungal agents against 3,378 Spanish clinical isolates of yeasts and filamentous fungi.

  Antimicrobial agents and chemotherapy 20060301

• [Systemic antifungals. Pharmacodynamics and pharmacokinetics].

  Revista iberoamericana de micologia 20060301

• Caspofungin for refractory candidemia in neonates.

  The Pediatric infectious disease journal 20060301

• Control of the C. albicans cell wall damage response by transcriptional regulator Cas5.

  PLoS pathogens 20060301

• Impact of alternate definitions of fever resolution on the composite endpoint in clinical trials of empirical antifungal therapy for neutropenic patients with persistent fever: analysis of results from the Caspofungin Empirical Therapy Study.

  Transplant infectious disease : an official journal of the Transplantation Society 20060301

• Combination of voriconazole and caspofungin as primary therapy for invasive aspergillosis in solid organ transplant recipients: a prospective, multicenter, observational study.

  Transplantation 20060215

• Caspofungin in the treatment of invasive fungal infections.

  Intensive & critical care nursing 20060201

• Fungal infections in solid organ transplantation.

  Expert opinion on pharmacotherapy 20060201

• Fungal infections in bone marrow transplant recipients.

  Expert opinion on pharmacotherapy 20060201

• Efficacy of caspofungin against invasive Candida or invasive Aspergillus infections in neutropenic patients.

  Cancer 20060115

• [Caspofungin: mode of action and therapeutic applications].

  La Revue de medecine interne 20060101

• Treatment of peritoneal dialysis related fungal peritonitis with caspofungin plus amphotericin B combination therapy.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060101

• Caspofungin treatment in severely ill, immunocompromised patients: a case-documentation study of 118 patients.

  The Journal of antimicrobial chemotherapy 20060101

• Successful treatment of fungus balls due to fluconazole-resistant Candida sake obstructing ureter stents in a renal transplant patient.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20060101

• Caspofungin treatment of Pneumocystis pneumonia during conditioning for bone marrow transplantation.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20060101

• Combination of caspofungin and an azole or an amphotericin B formulation in invasive fungal infections.

  The Journal of infection 20060101

• In vitro activities of caspofungin, amphotericin B and azoles against Coccidioides posadasii strains from Northeast, Brazil.

  Mycopathologia 20060101

• Combination therapy of disseminated coccidioidomycosis with caspofungin and fluconazole.

  BMC infectious diseases 20060101

• Successful treatment of Candida parapsilosis mural endocarditis with combined caspofungin and voriconazole.

  BMC infectious diseases 20060101

• Combined mucormycosis and Aspergillosis of the rhinocerebral region.

  In vivo (Athens, Greece) 20060101

• Combined trimethoprim and caspofungin treatment for severe Pneumocystis jiroveci pneumonia in a five year old boy with acute lymphoblastic leukemia.

  Klinische Padiatrie 20060101

• Caspofungin treatment in two infants with persistent fungaemia due to Candida lipolytica.

  Scandinavian journal of infectious diseases 20060101

• Successful treatment of Candida parapsilosis (fluconazole-resistant) osteomyelitis with caspofungin in a HIV patient.

  Scandinavian journal of infectious diseases 20060101

• Limitations of caspofungin in the treatment of obstructive pyonephrosis due to Candida glabrata infection.

  BMC infectious diseases 20060101

• Disseminated invasive aspergillosis in a patient with acute leukaemia.

  Acta bio-medica : Atenei Parmensis 20060101

• Successful combined antifungal salvage therapy with liposomal amphothericin B and caspofungin for invasive Aspergillus flavus infection in a child following allogeneic bone marrow transplantation.

  Acta bio-medica : Atenei Parmensis 20060101

• [Efficacies and clinical roles of new antifungal agents].

  Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20060101

• [Antifungals cellular targets and mechanisms of resistance].

  Therapie 20060101

• Native valve Aspergillus endocarditis in two patients with aplastic anaemia.

  Scandinavian journal of infectious diseases 20060101

• Severe Candida albicans panophthalmitis treated with all available and potentially effective antifungal drugs: fluconazole, liposomal amphotericin B, caspofungin, and voriconazole.

  Scandinavian journal of infectious diseases 20060101

• A case of candida albicans mediastinitis after heart transplantation successfully treated with caspofungin.

  Annals of transplantation 20060101

• The echinocandins: comparison of their pharmacokinetics, pharmacodynamics and clinical applications.

  Pharmacology 20060101

• Successful treatment of azole-resistant chronic mucocutaneous candidosis with caspofungin.

  Acta dermato-venereologica 20060101

• [Isolated renal mucormicosis].

  Gaceta medica de Mexico 20060101

• An update on the use of antifungal agents.

  Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia 20060101

• In vitro activity of caspofungin against planktonic and sessile Candida sp. cells.

  Polish journal of microbiology 20060101

• Empirical anti-Candida therapy among selected patients in the intensive care unit: a cost-effectiveness analysis.

  Annals of internal medicine 20051220

• Safety and potential of drug interactions of caspofungin and voriconazole in multimorbid patients.

  Pharmacology 20051201

• Experience with caspofungin in the treatment of persistent fungemia in neonates.

  Journal of perinatology : official journal of the California Perinatal Association 20051201

• Septic Candida krusei thrombophlebitis of inferior vena cava with persistent fungemia successfully treated by new antifungal agents.

  Medical mycology 20051201

• [Antifungal inhibitors of glucan synthesis].

  Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20051201

• Successful treatment of rhinocerebral zygomycosis with a combination of caspofungin and liposomal amphotericin B.

  Haematologica 20051201

• Comparison of galactomannan detection, PCR-enzyme-linked immunosorbent assay, and real-time PCR for diagnosis of invasive aspergillosis in a neutropenic rat model and effect of caspofungin acetate.

  Clinical and diagnostic laboratory immunology 20051101

• Candida glabrata prosthetic valve endocarditis treated successfully with fluconazole plus caspofungin without surgery: a case report and literature review.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20051101

• Mediastinal mass due to Aspergillus fumigatus after lung transplantation: a case report.

  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20051101

• Suitability of caspofungin for aerosol delivery: physicochemical profiling and nebulizer choice.

  Chest 20051101

• Aspergillus flavus scleritis: successful treatment with voriconazole and caspofungin.

  Medical mycology 20051101

• Absence of clinically relevant effect of caspofungin on cyclosporin pharmacokinetics.

  Swiss medical weekly 20051029

• Liquid chromatography-mass spectrometry using the hydrogen/deuterium exchange reaction as a tool for impurity identification in pharmaceutical process development.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051025

• Caspofungin is less nephrotoxic than amphotericin B in vitro and predominantly damages distal renal tubular cells.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20051001

• Cell wall integrity is dependent on the PKC1 signal transduction pathway in Cryptococcus neoformans.

  Molecular microbiology 20051001

• Epidemiology and outcome of infections due to Aspergillus terreus: 10-year single centre experience.

  British journal of haematology 20051001

• Caspofungin: an overview.

  Expert review of anti-infective therapy 20051001

• Drug-drug interactions of antifungal agents and implications for patient care.

  Expert opinion on pharmacotherapy 20051001

• Advances in antifungal therapy.

  The Pediatric infectious disease journal 20051001

• Cryptococcal fungemia in a neutropenic patient with AIDS while receiving caspofungin.

  The Journal of infection 20051001

• Voriconazole for candidosis: an important addition?

  Lancet (London, England) 20051001

• Breakthrough invasive infection due to Debaryomyces hansenii (teleomorph Candida famata) and Scopulariopsis brevicaulis in a stem cell transplant patient receiving liposomal amphotericin B and caspofungin for suspected aspergillosis.

  Infection 20051001

• Hsp90 potentiates the rapid evolution of new traits: drug resistance in diverse fungi.

  Science (New York, N.Y.) 20050930

• Experimental systemic murine aspergillosis: treatment with polyene and caspofungin combination and G-CSF.

  The Journal of antimicrobial chemotherapy 20050901

• Anti-metabolic activity of caspofungin against Candida albicans and Candida parapsilosis biofilms.

  The Journal of antimicrobial chemotherapy 20050901

• Caspofungin as first line therapy of pulmonary invasive fungal infections in 32 immunocompromised patients with hematologic malignancies.

  European journal of haematology 20050901

• Caspofungin treatment failure in a patient with invasive candidiasis and concomitant rifampicin treatment.

  International journal of antimicrobial agents 20050901

• Successful treatment of Fusarium endophthalmitis with voriconazole and Aspergillus endophthalmitis with voriconazole plus caspofungin.

  American journal of ophthalmology 20050901

• Combination antifungal therapy for invasive aspergillosis: utilizing new targeting strategies.

  Current drug targets. Infectious disorders 20050901

• Safety of caspofungin for treating invasive nasal sinus aspergillosis in a kidney transplant recipient.

  Transplantation proceedings 20050901

• [Economic evaluation of the treatment of systemic fungal infections in immunocompromised patients: the role of itraconazole].

  Recenti progressi in medicina 20050901

• Emergence of disseminated candidiasis caused by Candida krusei during treatment with caspofungin: case report and review of literature.

  Medical mycology 20050901

• Oral epithelial cell antifungal activity: approaches to evaluate a broad range of clinical conditions.

  Medical mycology 20050901

• Subtherapeutic ocular penetration of caspofungin and associated treatment failure in Candida albicans endophthalmitis.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050801

• Neonatal cutaneous fungal infections.

  Current opinion in pediatrics 20050801

• In vitro interaction of posaconazole and caspofungin against clinical isolates of Candida glabrata.

  Antimicrobial agents and chemotherapy 20050801

• Antifungal treatment in pediatric patients.

  Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20050801

• Echinocandins: role in antifungal therapy, 2005.

  Expert opinion on pharmacotherapy 20050801

• Yapsins are a family of aspartyl proteases required for cell wall integrity in Saccharomyces cerevisiae.

  Eukaryotic cell 20050801

• Efficacy of Abelcet and caspofungin, alone or in combination, against CNS aspergillosis in a murine model.

  The Journal of antimicrobial chemotherapy 20050701

• Evaluation of serum sandwich enzyme-linked immunosorbent assay for circulating galactomannan during caspofungin therapy: results from the caspofungin invasive aspergillosis study.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050701

• Cryptococcus neoformans resistance to echinocandins: (1,3)beta-glucan synthase activity is sensitive to echinocandins.

  Antimicrobial agents and chemotherapy 20050701

• Pharmacological properties and clinical efficacy of a recently licensed systemic antifungal, caspofungin.

  Mycoses 20050701

• In vitro susceptibility of 15 strains of zygomycetes to nine antifungal agents as determined by the NCCLS M38-A microdilution method.

  Mycoses 20050701

• Successful antifungal combination therapy with voriconazole and caspofungin.

  Pediatric blood & cancer 20050615

• [Update on therapy of invasive mycoses in hematology and oncology].

  Deutsche medizinische Wochenschrift (1946) 20050603

• Candida krusei fungemia in an unrelated allogeneic hematopoietic stem cell transplant patient successfully treated with Caspofungin.

  Bone marrow transplantation 20050601

• Effect of media composition and in vitro activity of posaconazole, caspofungin and voriconazole against zygomycetes.

  The Journal of antimicrobial chemotherapy 20050601

• Invasive candidiasis in cancer patients: observations from a randomized clinical trial.

  The Journal of infection 20050601

• Genome-wide expression profiling of the response to azole, polyene, echinocandin, and pyrimidine antifungal agents in Candida albicans.

  Antimicrobial agents and chemotherapy 20050601

• Antifungal agents in children.

  Pediatric clinics of North America 20050601

• Voriconazole: review of a broad spectrum triazole antifungal agent.

  Expert opinion on pharmacotherapy 20050601

• [Comments about 'Management of aspergillosis in immunocompromised patients. Recommendations of Lille University Hospital--4th version--November 2004'].

  Medecine et maladies infectieuses 20050601

• Successful treatment of disseminated Aspergillosis in a leukemic child.

  Puerto Rico health sciences journal 20050601

• Caspofungin versus amphotericin B for candidemia: a pharmacoeconomic analysis.

  Clinical therapeutics 20050601

• Hepatic uptake of the novel antifungal agent caspofungin.

  Drug metabolism and disposition: the biological fate of chemicals 20050501

• Cerebral aspergillosis in the critically ill: two cases of successful medical treatment.

  Intensive care medicine 20050501

• Successful treatment of disseminated aspergillosis with the combination of voriconazole, caspofungin, granulocyte transfusions, and surgery followed by allogeneic blood stem cell transplantation in a patient with primary failure of an autologous stem cell graft.

  European journal of haematology 20050501

• Exposure of Candida albicans to antifungal agents affects expression of SAP2 and SAP9 secreted proteinase genes.

  The Journal of antimicrobial chemotherapy 20050501

• Candida prosthetic valve endocarditis cured by caspofungin therapy without valve replacement.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050501

• A case of Aspergillus mediastinitis after heart transplantation successfully treated with liposomal amphotericin B, caspofungin and voriconazole.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20050501

• Characterization of Aspergillus fumigatus mutants with reduced susceptibility to caspofungin.

  Medical mycology 20050501

• Salvage therapy with caspofungin for invasive aspergillosis: results from the caspofungin compassionate use study.

  The Journal of infection 20050401

• Caspofungin for invasive fungal infections: combination treatment with liposomal amphotericin B in children undergoing hemopoietic stem cell transplantation.

  Pediatric transplantation 20050401

• Candida tropicalis arthritis of the knee in a patient with acute lymphoblastic leukaemia: successful treatment with caspofungin.

  Hong Kong medical journal = Xianggang yi xue za zhi 20050401

• Combination antifungal therapy for invasive aspergillosis.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050401

• Systemic aspergillosis with predominant genitourinary manifestations in an immunocompetent man: what we can learn from a disastrous follow-up.

  Infection 20050401

• Candida glabrata endophthalmitis treated successfully with caspofungin.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050301

• Caspofungin: a new therapeutic option for fungal endocarditis.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20050301

• Caspofungin as treatment for Candida glabrata hip infection.

  International journal of antimicrobial agents 20050301

• Efficacy of caspofungin in prophylaxis and treatment of an adult leukemic patient with invasive pulmonary aspergillosis in allogeneic stem cell transplantation.

  Mycoses 20050301

• Caspofungin as second-line therapy for fever of unknown origin or invasive fungal infection following allogeneic stem cell transplantation.

  Bone marrow transplantation 20050301

• Studies of the paradoxical effect of caspofungin at high drug concentrations.

  Diagnostic microbiology and infectious disease 20050301

• In vitro activity of caspofungin compared to amphotericin B, fluconazole, and itraconazole against Candida strains isolated in a Turkish University Hospital.

  Medical mycology 20050301

• Caspofungin versus liposomal amphotericin B for empirical therapy.

  The New England journal of medicine 20050127

• Caspofungin versus liposomal amphotericin B for empirical therapy.

  The New England journal of medicine 20050127

• Caspofungin versus liposomal amphotericin B for empirical therapy.

  The New England journal of medicine 20050127

• Caspofungin versus liposomal amphotericin B for empirical therapy.

  The New England journal of medicine 20050127

• Caspofungin versus liposomal amphotericin B for empirical therapy.

  The New England journal of medicine 20050127

• Caspofungin versus liposomal amphotericin B for empirical therapy.

  The New England journal of medicine 20050127

• [Caspofungin in the replacement of amphotericin B in the treatment of fungal diseases].

  Zhonghua yi xue za zhi 20050105

• Evaluation of Mycograb, amphotericin B, caspofungin, and fluconazole in combination against Cryptococcus neoformans by checkerboard and time-kill methodologies.

  Diagnostic microbiology and infectious disease 20050101

• Management of endogenous fungal endophthalmitis with voriconazole and caspofungin.

  American journal of ophthalmology 20050101

• New antifungal drugs and the pediatric cancer patient: current status of clinical development.

  Klinische Padiatrie 20050101

• Caspofungin and amphotericin B for disseminated Fusarium verticillioides in leukemia.

  The Annals of pharmacotherapy 20050101

• [Hepatosplenic and kidneys candidasis complicating an acute myeloblastic leukemia. A case treated with voriconazole and caspofungin].

  Annales de biologie clinique 20050101

• Hope for patients with neoplastic disease and invasive fungal infections.

  The journal of supportive oncology 20050101

• Caspofungin: a review of its use in the treatment of fungal infections.

  Drugs 20050101

• [Fungal peritonitis episodes in a peritoneal dialysis centre during a 10-year period: a report of 11 cases].

  Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20050101

• Efficacy and safety of caspofungin for treatment of invasive aspergillosis in patients refractory to or intolerant of conventional antifungal therapy.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20041201

• Caspofungin therapy of neonates with invasive candidiasis.

  The Pediatric infectious disease journal 20041201

• Antifungal resistance: the clinical front.

  Oncology (Williston Park, N.Y.) 20041201

• Combinations of antifungal agents in therapy--what value are they?

  The Journal of antimicrobial chemotherapy 20041101

• Pharmacokinetics/pharmacodynamics of echinocandins.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20041101

• In-vitro activity of nikkomycin Z alone and in combination with polyenes, triazoles or echinocandins against Aspergillus fumigatus.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20041101

• New type of effective antifungal treatment identified.

  The Lancet. Oncology 20041101

• Use of newer antifungal therapies in clinical practice: what do the data tell us?

  Oncology (Williston Park, N.Y.) 20041101

• Combination antifungal therapy: where are we now, and where are we going?

  Oncology (Williston Park, N.Y.) 20041101

• Pharmacodynamics of caspofungin in a murine model of invasive pulmonary aspergillosis: evidence of concentration-dependent activity.

  The Journal of infectious diseases 20041015

• Failure of caspofungin to treat brain abscesses secondary to Candida albicans prosthetic valve endocarditis.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20041015

• Refractory pulmonary aspergillosis treated with caspofungin after heart-lung transplantation.

  Transplant international : official journal of the European Society for Organ Transplantation 20041001

• Disseminated mucormycosis associated with invasive pulmonary aspergillosis in a patient treated for post-transplant high-grade non-Hodgkin's lymphoma.

  Leukemia & lymphoma 20041001

• Native valve endocarditis due to Candida glabrata treated without valvular replacement: a potential role for caspofungin in the induction and maintenance treatment.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20041001

• Caspofungin: a potential cause of reversible severe thrombocytopenia.

  Pharmacotherapy 20041001

• Caspofungin versus liposomal amphotericin B for empirical antifungal therapy in patients with persistent fever and neutropenia.

  The New England journal of medicine 20040930

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  The New England journal of medicine 20040930

• Combination antifungal therapy for invasive aspergillosis.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040915

• Combination therapy for invasive aspergillosis.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040915

• Echinocandins: ask not what they can do for esophageal candidiasis--ask what studies of esophageal candidiasis can do for them.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040915

• Use of the echinocandins (caspofungin) in the treatment of disseminated coccidioidomycosis in a renal transplant recipient.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040915

• Effects of caspofungin (MK-0991) and anidulafungin (LY303366) on phagocytosis, oxidative burst and killing of Candida albicans by human phagocytes.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20040901

• Efficacy and feasibility of aerosolized amphotericin B lipid complex therapy in caspofungin breakthrough pulmonary zygomycosis.

  Bone marrow transplantation 20040901

• Retrospective study of the hepatic safety profile of patients concomitantly treated with caspofungin and cyclosporin A.

  Transplant infectious disease : an official journal of the Transplantation Society 20040901

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  Nederlands tijdschrift voor geneeskunde 20040821

• Trichosporon asahii infection treated with caspofungin combined with liposomal amphotericin B.

  The Journal of antimicrobial chemotherapy 20040801

• Effects of several antifungal drug combinations against clinical and environmental isolates of Cryptococcus neoformans from China.

  Mycoses 20040801

• Safety of the concomitant use of caspofungin and cyclosporin A in patients with invasive fungal infections.

  Bone marrow transplantation 20040701

• Safety and efficacy of caspofungin and liposomal amphotericin B, followed by voriconazole in young patients affected by refractory invasive mycosis.

  European journal of haematology 20040701

• Treatment of meningeal coccidioidomycosis with caspofungin.

  The Journal of antimicrobial chemotherapy 20040701

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  Annals of hematology 20040601

• Assessing the antifungal activity and toxicity profile of amphotericin B lipid complex (ABLC; Abelcet) in combination with caspofungin in experimental systemic aspergillosis.

  Journal of pharmaceutical sciences 20040601

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  The Pediatric infectious disease journal 20040601

• In vitro evaluation of cytochrome P450-mediated drug interactions between cytarabine, idarubicin, itraconazole and caspofungin.

  Hematology (Amsterdam, Netherlands) 20040601

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  Revue de pneumologie clinique 20040601

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  The Journal of antimicrobial chemotherapy 20040501

• Successful treatment of concomitant pulmonary zygomycosis and aspergillosis with a combination of amphotericin B lipid complex, caspofungin, and voriconazole in a patient on immunosuppression for chronic graft-versus-host disease.

  Bone marrow transplantation 20040501

• Differential effects of the combination of caspofungin and terbinafine against Candida albicans, Candida dubliniensis and Candida kefyr.

  International journal of antimicrobial agents 20040501

• Compliance in two medical centers with criteria for use of caspofungin and lipid-based amphotericin B.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040501

• Analysis of beta-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofungin.

  Genetics 20040501

• Treatment of candidal cholangitis with caspofungin therapy in a patient with a liver transplant: documentation of biliary excretion of caspofungin.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040401

• Caspofungin for Candida endocarditis.

  The Pediatric infectious disease journal 20040401

• New options for the treatment of invasive fungal infections.

  Seminars in oncology 20040401

• Successful treatment of chronic disseminated candidiasis with caspofungin and itraconazole in a patient with progressive acute leukemia and prolonged neutropenia.

  International journal of hematology 20040401

• Caspofungin modulates in vitro adherence of Candida albicans to plastic coated with extracellular matrix proteins.

  The Journal of antimicrobial chemotherapy 20040301

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  Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20040301

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  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20040301

• Caspofungin associated with liposomal amphotericin B or voriconazole for treatment of refractory fungal pneumonia in children with acute leukaemia or undergoing allogeneic bone marrow transplant.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20040301

• Newer antifungal agents.

  Indian journal of pediatrics 20040301

• Deep sinus aspergillosis in a liver transplant recipient successfully treated with a combination of caspofungin and voriconazole.

  Transplant infectious disease : an official journal of the Transplantation Society 20040301

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  The Journal of infection 20040101

• [symbol: see text]Caspofungin and [symbol: see text]voriconazole for fungal infections.

  Drug and therapeutics bulletin 20040101

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  Acta clinica Belgica 20040101

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  Enfermedades infecciosas y microbiologia clinica 20040101

• An advanced double column-switching technique (LC-LC) for liquid chromatography/electrospray ionisation tandem mass spectrometry for fully automated analysis of caspofungin.

  Rapid communications in mass spectrometry : RCM 20040101

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  Eukaryotic cell 20031201

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  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20031201

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  Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20031201

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  Diagnostic microbiology and infectious disease 20031001

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  Seminars in perinatology 20031001

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  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20030901

• First reported use of caspofungin in an extremely low-birth-weight neonate.

  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20030901

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  Revista iberoamericana de micologia 20030901

• Global distribution and outcomes for Candida species causing invasive candidiasis: results from an international randomized double-blind study of caspofungin versus amphotericin B for the treatment of invasive candidiasis.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20030801

• Activities of caspofungin, itraconazole, posaconazole, ravuconazole, voriconazole, and amphotericin B against 448 recent clinical isolates of filamentous fungi.

  Journal of clinical microbiology 20030801

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  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20030801

• Efficacy and toxicity of caspofungin in combination with liposomal amphotericin B as primary or salvage treatment of invasive aspergillosis in patients with hematologic malignancies.

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  Expert opinion on pharmacotherapy 20030501

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  Critical care medicine 20030501

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  Molecular microbiology 20030401

• Comment: caspofungin acetate for treatment of invasive fungal infections.

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  The New England journal of medicine 20030327

• In vitro activities of caspofungin compared with those of fluconazole and itraconazole against 3,959 clinical isolates of Candida spp., including 157 fluconazole-resistant isolates.

  Antimicrobial agents and chemotherapy 20030301

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  International journal of clinical practice 20030301

• Refractory Aspergillus pneumonia in patients with acute leukemia: successful therapy with combination caspofungin and liposomal amphotericin.

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  AIDS (London, England) 20030214

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  The Journal of antimicrobial chemotherapy 20030201

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  The Pediatric infectious disease journal 20030201

• In vitro activity of voriconazole, itraconazole, caspofungin, anidulafungin (VER002, LY303366) and amphotericin B against aspergillus spp.

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  Nihon rinsho. Japanese journal of clinical medicine 20030201

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  The Journal of antimicrobial chemotherapy 20030101

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  Pharmazie in unserer Zeit 20030101

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  Pharmazie in unserer Zeit 20030101

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  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20030101

• Review of the safety, tolerability, and drug interactions of the new antifungal agents caspofungin and voriconazole.

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• Caspofungin: a review of its use in oesophageal candidiasis, invasive candidiasis and invasive aspergillosis.

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  Scandinavian journal of infectious diseases 20030101

• CNS-aspergillosis: are there new treatment options?

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  Mycoses 20030101

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  The New England journal of medicine 20021219

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  Drugs of today (Barcelona, Spain : 1998) 20021201

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• Successful treatment with caspofungin of hepatosplenic candidiasis resistant to liposomal amphotericin B.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20021101

• Efficacy of caspofungin in the treatment of esophageal candidiasis resistant to fluconazole.

  Journal of acquired immune deficiency syndromes (1999) 20021001

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  Current opinion in investigational drugs (London, England : 2000) 20021001

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  Antimicrobial agents and chemotherapy 20020901

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  AIDS research and human retroviruses 20020901

• A randomized double-blind study of caspofungin versus fluconazole for the treatment of esophageal candidiasis.

  The American journal of medicine 20020901

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  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020801

• Combined antifungal treatment of visceral mucormycosis with caspofungin and liposomal amphotericin B.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20020801

• Caspofungin versus amphotericin B for the treatment of Candidal esophagitis.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020701

• New drugs, old drugs - dear drugs, cheap drugs.

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• Resolution of multidrug-refractory oesophageal candidiasis in an AIDS patient after treatment with caspofungin.

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  Journal of clinical microbiology 20020601

• Amphotericin B-resistant Aspergillus flavus infection successfully treated with caspofungin, a novel antifungal agent.

  Journal of the American Academy of Dermatology 20020601

• Progressive cutaneous hyalohyphomycosis due to Paecilomyces lilacinus: rapid response to treatment with caspofungin and itraconazole.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020515

• Antifungal activities of fluconazole, caspofungin (MK0991), and anidulafungin (LY 303366) alone and in combination against Candida spp. and Crytococcus neoformans via time-kill methods.

  Diagnostic microbiology and infectious disease 20020501

• Caspofungin in combination with itraconazole for the treatment of invasive aspergillosis in humans.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020415

• [First echinocandin on the market. New type of antifungal against Aspergillus & Co].

  MMW Fortschritte der Medizin 20020409

• Moisture assay of an antifungal by near-infrared diffuse reflectance spectroscopy.

  Journal of pharmaceutical and biomedical analysis 20020401

• New drugs 2002. Part II.

  Nursing 20020401

• Caspofungin: an echinocandin antifungal agent.

  Clinical therapeutics 20020301

• Safety and tolerability of caspofungin acetate in the treatment of fungal infections.

  Transplant infectious disease : an official journal of the Transplantation Society 20020301

• New antifungal agents-treatment standards are beginning to grow old.

  The Journal of antimicrobial chemotherapy 20020201

• Combination therapy with caspofungin and amphotericin B lipid complex.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20020101

• The first echinocandin: caspofungin.

  Mycoses 20020101

• Clinical efficacy of echinocandin antifungals.

  Current opinion in infectious diseases 20011201

• A randomized double-blind study of caspofungin versus amphotericin for the treatment of candidal esophagitis.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20011101

• The echinocandins, first novel class of antifungals in two decades: will they live up to their promise?

  International journal of clinical practice 20011101

• Caspofungin acetate, bivalirudin.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20011001

• [Caspofungin. A new antimycotic agents from the echinocandin group].

  Medizinische Monatsschrift fur Pharmazeuten 20010901

• Caspofungin: pharmacology, safety and therapeutic potential in superficial and invasive fungal infections.

  Expert opinion on investigational drugs 20010801

• Caspofungin (Cancidas) for aspergillosis.

  The Medical letter on drugs and therapeutics 20010709

• Determination of an echinocandin, MK-0991, in mammalian plasma by radioimmunoassay.

  Journal of pharmaceutical and biomedical analysis 20010701

• Caspofungin acetate: an antifungal agent.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20010701

• New type of antifungal approved for invasive aspergillosis.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20010401

• Fungal treatment approved.

  AIDS patient care and STDs 20010401

• Hitting a new target with echinocandins. Why chase something else?

  Current opinion in investigational drugs (London, England : 2000) 20010401

• Update on antifungals targeted to the cell wall: focus on beta-1,3-glucan synthase inhibitors.

  Expert opinion on investigational drugs 20010201

• In vitro susceptibility testing methods for caspofungin against Aspergillus and Fusarium isolates.

  Antimicrobial agents and chemotherapy 20010101

• New drug fights invasive fungal infection.

  FDA consumer 20010101

• Caspofungin.

  Drugs 20010101

• Federal Drug Administration panel recommends approval of Cancidas, Merck's investigational antifungal drug.

  The Journal of the Association of Nurses in AIDS Care : JANAC 20010101

• Pharmacological update on new infusion drugs.

  Journal of infusion nursing : the official publication of the Infusion Nurses Society 20010101

• Caspofungin: the first of a new class of antifungal agents.

  Cancer practice 20010101

• The effect of the echinocandin analogue caspofungin on cell wall glucan synthesis by Cryptococcus neoformans.

  The Journal of infectious diseases 20001201

• Efficacy of the echinocandin caspofungin against disseminated aspergillosis and candidiasis in cyclophosphamide-induced immunosuppressed mice.

  Antimicrobial agents and chemotherapy 20000901

• Comparison of the echinocandin caspofungin with amphotericin B for treatment of histoplasmosis following pulmonary challenge in a murine model.

  Antimicrobial agents and chemotherapy 20000701

• Synergistic antifungal activities of bafilomycin A(1), fluconazole, and the pneumocandin MK-0991/caspofungin acetate (L-743,873) with calcineurin inhibitors FK506 and L-685,818 against Cryptococcus neoformans.

  Antimicrobial agents and chemotherapy 20000301

• In vitro activity of the new echinocandin antifungal, MK-0991, against common and uncommon clinical isolates of Candida species.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 19990401

• In vitro pharmacodynamic properties of MK-0991 determined by time-kill methods.

  Diagnostic microbiology and infectious disease 19990201

• Comparison of In vitro activities of the new triazole SCH56592 and the echinocandins MK-0991 (L-743,872) and LY303366 against opportunistic filamentous and dimorphic fungi and yeasts.

  Journal of clinical microbiology 19981001

• In vitro preclinical evaluation studies with the echinocandin antifungal MK-0991 (L-743,872).

  Antimicrobial agents and chemotherapy 19971101

• Evaluation of the echinocandin antifungal MK-0991 (L-743,872): efficacies in mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis.

  Antimicrobial agents and chemotherapy 19971101

• Comparison of the in vitro activities of the echinocandin LY303366, the pneumocandin MK-0991, and fluconazole against Candida species and Cryptococcus neoformans.

  Antimicrobial agents and chemotherapy 19970901

• Treatment of murine disseminated candidiasis with L-743,872.

  Antimicrobial agents and chemotherapy 19970801

• In vitro activity of a new pneumocandin antifungal, L-743,872, against azole-susceptible and -resistant Candida species.

  Antimicrobial agents and chemotherapy 19970701

• In vitro growth-inhibitory activity of pneumocandins L-733,560 and L-743,872 against putatively amphotericin B- and fluconazole-resistant Candida isolates: influence of assay conditions.

  Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology 19970101