180465-02-5 | S-(+)-Cbpg

Packsize	Purity	Availability	Price	Discounted Price
5mg	95%	in stock	$575.00	$402.00
25mg	95%	in stock	$1,289.00	$902.00

Description

• Catalog Number: AA95710
• Chemical Name: S-(+)-Cbpg
• CAS Number: 180465-02-5
• Molecular Formula: C8H11NO4
• Molecular Weight: 185.1772
• MDL Number: MFCD00949088
• SMILES: OC(=O)[C@H](C12CC(C1)(C2)C(=O)O)N

Computed Properties

• Complexity: 279
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 3
• XLogP3: -3.3

Upstream Synthesis Route

The compound 3-[(S)-amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-carboxylic acid, also known as $name$, is a versatile building block in chemical synthesis due to its unique structure and reactivity. In chemical synthesis, this compound can serve as a key intermediate for the preparation of various pharmaceuticals, agrochemicals, and specialty chemicals. Its compact bicyclic structure and the presence of both amino and carboxylic acid functional groups make it an ideal starting material for the synthesis of complex molecules.One significant application of $name$ in chemical synthesis is as a chiral ligand for asymmetric catalysis. The chiral center in the molecule allows for the formation of enantioselective products, making it a valuable tool for the synthesis of enantiomerically pure compounds. By incorporating $name$ into the catalyst design, chemists can control the stereochemistry of the reactions, leading to the formation of highly valuable chiral products.Moreover, the carboxylic acid group in $name$ can participate in various chemical reactions such as amidation, esterification, and peptide coupling, enabling the attachment of different functional groups to the molecule. This flexibility in functionalization allows for the tailored modification of $name$ to suit the specific needs of a synthetic route.Overall, the multifunctional nature of 3-[(S)-amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-carboxylic acid makes it a valuable component in chemical synthesis, providing chemists with a powerful tool for the construction of complex and diverse molecular architectures.

Literature

• Propofol: neuroprotection in an in vitro model of traumatic brain injury.

  Critical care (London, England) 20090101

• Argon: neuroprotection in in vitro models of cerebral ischemia and traumatic brain injury.

  Critical care (London, England) 20090101

• Activation of mGlu1 but not mGlu5 metabotropic glutamate receptors contributes to postischemic neuronal injury in vitro and in vivo.

  Pharmacology, biochemistry, and behavior 20020901

• Activation of type 5 metabotropic glutamate receptors enhances NMDA responses in mice cortical wedges.

  British journal of pharmacology 20010201

• Biochemical and electrophysiological studies on (S)-(+)-2-(3'-carboxybicyclo(1.1.1)pentyl)-glycine (CBPG), a novel mGlu5 receptor agonist endowed with mGlu1 receptor antagonist activity.

  Neuropharmacology 19990701