18085-97-7 | Jaceosidin

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$42.00	$30.00
5mg	98%	in stock	$138.00	$97.00

Description

• Catalog Number: AA96202
• Chemical Name: Jaceosidin
• CAS Number: 18085-97-7
• Molecular Formula: C17H14O7
• Molecular Weight: 330.2889
• MDL Number: MFCD01081948
• SMILES: COc1cc(ccc1O)c1cc(=O)c2c(o1)cc(c(c2O)OC)O

Computed Properties

• Complexity: 505
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 24
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 3
• XLogP3: 1.7

Literature

• Jaceosidin induces apoptosis through Bax activation and down-regulation of Mcl-1 and c-FLIP expression in human renal carcinoma Caki cells.

  Chemico-biological interactions 20161225

• Flavonoids from the Japanese monotypic genus, Nipponanthemum.

  Natural product communications 20120801

• Oroxylin A analogs exhibited strong inhibitory activities against iNOS-mediated nitric oxide (NO) production.

  Bioorganic & medicinal chemistry letters 20120401

• Suppressive effects of Schizandra chinensis Baillon water extract on allergy-related cytokine generation and degranulation in IgE-antigen complex-stimulated RBL-2H3 cells.

  Nutrition research and practice 20120401

• [Chemical constituents of Eupatorium lindleyanum].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120401

• A new flavonoid and other constituents from Centaurea nicaeensis All. var. walliana M.

  Natural product research 20120101

• Jaceosidin Induces Apoptosis in U87 Glioblastoma Cells through G2/M Phase Arrest.

  Evidence-based complementary and alternative medicine : eCAM 20120101

• Effect of a New Prokinetic Agent DA-9701 Formulated with Corydalis Tuber and Pharbitidis Semen on Cytochrome P450 and UDP-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes.

  Evidence-based complementary and alternative medicine : eCAM 20120101

• In vitro evaluation of flavonoids from Eriodictyon californicum for antagonist activity against the bitterness receptor hTAS2R31.

  Journal of agricultural and food chemistry 20111228

• The relevance of higher plants in lead compound discovery programs.

  Journal of natural products 20110624

• Jaceosidin inhibits contact hypersensitivity in mice via down-regulating IFN-γ/STAT1/T-bet signaling in T cells.

  European journal of pharmacology 20110125

• Neuropharmacological activity of Lippia nodiflora Linn.

  Pharmacognosy research 20110101

• Systematic review of herbals as potential anti-inflammatory agents: Recent advances, current clinical status and future perspectives.

  Pharmacognosy reviews 20110101

• Jaceosidin induces p53-dependent G2/M phase arrest in U87 glioblastoma cells.

  Asian Pacific journal of cancer prevention : APJCP 20110101

• Metabolism study of botanical drugs.

  Archives of pharmacal research 20101201

• In vitro metabolism of jaceosidin and characterization of cytochrome P450 and UDP-glucuronosyltransferase enzymes in human liver microsomes.

  Archives of pharmacal research 20101201

• Effects of eupatilin and jaceosidin on cytochrome p450 enzyme activities in human liver microsomes.

  Molecules (Basel, Switzerland) 20100916

• A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors.

  Bioorganic & medicinal chemistry 20100201

• Inhibitory effect of eupatilin and jaceosidin isolated from Artemisia princeps on carrageenan-induced inflammation in mice.

  Journal of ethnopharmacology 20090925

• Liquid chromatography-tandem mass spectrometry for the determination of jaceosidin in rat plasma.

  Journal of pharmaceutical and biomedical analysis 20090220

• Anti-inflammatory and immunosuppressive effect of flavones isolated from Artemisia vestita.

  Journal of ethnopharmacology 20081030

• In vitro antioxidant and anti-inflammatory activities of Jaceosidin from Artemisia princeps Pampanini cv. Sajabal.

  Archives of pharmacal research 20080401

• Jaceosidin induces apoptosis in human ovary cancer cells through mitochondrial pathway.

  Journal of biomedicine & biotechnology 20080101

• Inhibitory effect of eupatilin and jaceosidin isolated from Artemisia princeps in IgE-induced hypersensitivity.

  International immunopharmacology 20071215

• Anti-inflammatory activity of flavonoids from Eupatorium arnottianum.

  Journal of ethnopharmacology 20070725

• Elemanolide sesquiterpenes and eudesmane sesquiterpene glycosides from Centaurea hierapolitana.

  Phytochemistry 20070301

• Jaceosidin, a pharmacologically active flavone derived from Artemisia argyi, inhibits phorbol-ester-induced upregulation of COX-2 and MMP-9 by blocking phosphorylation of ERK-1 and -2 in cultured human mammary epithelial cells.

  Annals of the New York Academy of Sciences 20070101

• Jaceosidin induces apoptosis in ras-transformed human breast epithelial cells through generation of reactive oxygen species.

  Annals of the New York Academy of Sciences 20070101

• Salicylic acid enhances Jaceosidin and Syringin production in cell cultures of Saussurea medusa.

  Biotechnology letters 20060701

• Methyl jasmonate stimulates jaceosidin and hispidulin production in cell cultures of Saussurea medusa.

  Applied biochemistry and biotechnology 20060701

• Flavonoids from Artemisia copa with anti-inflammatory activity.

  Planta medica 20060101

• Inhibitory effect of jaceosidin isolated from Artemisiaargyi on the function of E6 and E7 oncoproteins of HPV 16.

  Journal of ethnopharmacology 20050426

• Cellular aggregate size as the critical factor for flavonoid production by suspension cultures of Saussurea medusa.

  Biotechnology letters 20050101

• Transformation of Saussurea medusa for hairy roots and jaceosidin production.

  Plant cell reports 20041201

• Free radical scavengers and antioxidants from Baccharis grisebachii.

  Journal of ethnopharmacology 20041201

• Active components from Artemisia iwayomogi displaying ONOO(-) scavenging activity.

  Phytotherapy research : PTR 20040101

• [Study on the flavonoids of Eupatorium lindleyanum].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040101

• Effect of aggregate size in cell cultures of Saussurea medusa on cell growth and jaceosidin production.

  Plant cell reports 20030701

• Antiproliferative constituents in plants 10. Flavones from the leaves of Lantana montevidensis Briq. and consideration of structure-activity relationship.

  Biological & pharmaceutical bulletin 20020701