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Protonation preferentially stabilizes minor tautomers of the halouracils: IRMPD action spectroscopy and theoretical studies.
Journal of the American Society for Mass Spectrometry 20120901
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A spectroscopic investigations of anticancer drugs binding to bovine serum albumin.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120301
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A rapid HPLC-ESI-MS/MS method for determination of dihydrouracil/uracil ratio in plasma: evaluation of toxicity to 5-flurouracil in patients with gastrointestinal cancer.
Therapeutic drug monitoring 20120201
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Benzene metabolite 1,2,4-benzenetriol induces halogenated DNA and tyrosines representing halogenative stress in the HL-60 human myeloid cell line.
Environmental health perspectives 20120101
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Electron transfer processes in potassium collisions with 5-fluorouracil and 5-chlorouracil.
Physical chemistry chemical physics : PCCP 20111228
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Chemical evolution of a bacterium's genome.
Angewandte Chemie (International ed. in English) 20110725
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Increasing tumoral 5-fluorouracil concentrations during a 5-day continuous infusion: a microdialysis study.
Cancer chemotherapy and pharmacology 20110501
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Photoelectron spectroscopic study of the negative ions of 4-thiouracil and 2,4-dithiouracil.
The Journal of chemical physics 20110221
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Photoelectron spectroscopic studies of 5-halouracil anions.
The Journal of chemical physics 20110107
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Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention.
Journal of clinical biochemistry and nutrition 20110101
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Anti-proliferation effects of Sirolimus sustained delivery film in rabbit glaucoma filtration surgery.
Molecular vision 20110101
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Epigenomics in environmental health.
Frontiers in genetics 20110101
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Characterization of a novel lymph node metastasis model from human colonic cancer and its preclinical use for comparison of anti-metastatic efficacy between oral S-1 and UFT/ LV.
Cancer science 20100801
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Polymerase incorporation and miscoding properties of 5-chlorouracil.
Chemical research in toxicology 20100419
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A new, validated HPLC-MS/MS method for the simultaneous determination of the anti-cancer agent capecitabine and its metabolites: 5'-deoxy-5-fluorocytidine, 5'-deoxy-5-fluorouridine, 5-fluorouracil and 5-fluorodihydrouracil, in human plasma.
Biomedical chromatography : BMC 20100401
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Paclitaxel inhibits growth, migration and collagen production of human Tenon's fibroblasts--potential use in drug-eluting glaucoma drainage devices.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20100201
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Comparative study of HOCl-inflicted damage to bacterial DNA ex vivo and within cells.
Archives of biochemistry and biophysics 20100115
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[Markers of chloric acid (I) in biological systems--identification and properties].
Postepy biochemii 20100101
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pH-Dependent configurations of a 5-chlorouracil-guanine base pair.
Biochemistry 20091201
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Base pairing configuration and stability of an oligonucleotide duplex containing a 5-chlorouracil-adenine base pair.
Biochemistry 20090811
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Retrospective analysis of S-1 monotherapy in patients with metastatic colorectal cancer after failure to fluoropyrimidine and irinotecan or to fluoropyrimidine, irinotecan and oxaliplatin.
Japanese journal of clinical oncology 20090501
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Significance of 5-fluorouracil-related enzyme activities in predicting sensitivity to 5-fluorouracil in bladder carcinoma.
Anticancer research 20090401
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Reactive oxygen and nitrogen species induce protein and DNA modifications driving arthrofibrosis following total knee arthroplasty.
Fibrogenesis & tissue repair 20090101
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Controlled delivery of 5-chlorouracil using poly(ortho esters) in filtering surgery for glaucoma.
Investigative ophthalmology & visual science 20080701
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Examination of hypochlorous acid-induced damage to cytosine residues in a CpG dinucleotide in DNA.
Chemical research in toxicology 20080601
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Gan to kagaku ryoho. Cancer & chemotherapy 20060601
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Myeloperoxidase generates 5-chlorouracil in human atherosclerotic tissue: a potential pathway for somatic mutagenesis by macrophages.
The Journal of biological chemistry 20060210
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Evaluation of novel one-electron reduction with metal in DNA.
Nucleic acids symposium series (2004) 20060101
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Hydrophilic interaction liquid chromatography-APCI-mass spectrometry determination of 5-fluorouracil in plasma and tissues.
Journal of pharmaceutical and biomedical analysis 20050715
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Measurement of drug release from microcarriers by microdialysis.
Journal of pharmaceutical sciences 20050701
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Influence of halogenation on the properties of uracil and its noncovalent interactions with alkali metal ions. Threshold collision-induced dissociation and theoretical studies.
Journal of the American Chemical Society 20041215
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Thymidylate synthase predictive power is overcome by irinotecan combination therapy with S-1 for gastric cancer.
British journal of cancer 20041004
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Synthesis and characterization of oligonucleotides containing 5-chlorocytosine.
Chemical research in toxicology 20040901
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Phase I and pharmacokinetic study of the oral fluoropyrimidine S-1 on a once-daily-for-28-day schedule in patients with advanced malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 20040801
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Synthesis and evaluation of 6-methylene-bridged uracil derivatives. Part 1: discovery of novel orally active inhibitors of human thymidine phosphorylase.
Bioorganic & medicinal chemistry 20040701
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Alternate-day oral therapy with TS-1 for advanced gastric cancer.
International journal of clinical oncology 20040601
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Electron attachment to chlorouracil: a comparison between 6-ClU and 5-ClU.
The Journal of chemical physics 20040108
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Phase I study of irinotecan and S-1 combination therapy in patients with metastatic gastric cancer.
International journal of clinical oncology 20031201
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5-Chlorouracil, a marker of DNA damage from hypochlorous acid during inflammation. A gas chromatography-mass spectrometry assay.
The Journal of biological chemistry 20030829
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Phagocytes produce 5-chlorouracil and 5-bromouracil, two mutagenic products of myeloperoxidase, in human inflammatory tissue.
The Journal of biological chemistry 20030627
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Analytical and pharmacokinetic studies with 5-chloro-2'-deoxycytidine.
Biochemical pharmacology 20021115
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Loss of oxidized and chlorinated bases in DNA treated with reactive oxygen species: implications for assessment of oxidative damage in vivo.
Biochemical and biophysical research communications 20020830
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Detection and quantification of 5-chlorocytosine in DNA by stable isotope dilution and gas chromatography/negative ion chemical ionization/mass spectrometry.
Chemical research in toxicology 20020201
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An improved resazurin-based cytotoxicity assay for hepatic cells.
Cell biology and toxicology 20020101
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N(1)-C(5')-linked dimer hydrates of 5-substituted uracils produced by anodic oxidation in aqueous solution.
The Journal of organic chemistry 20010406
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Simultaneous determination of flucytosine and fluorouracil in human plasma by high-performance liquid chromatography.
Biomedical chromatography : BMC 20010401
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Determination of 5-fluorouracil in environmental samples by solid-phase extraction and high-performance liquid chromatography with ultraviolet detection.
Journal of chromatography. B, Biomedical sciences and applications 20010105
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Synthesis of 5-chloro-1-(2,3-dideoxy-3-fluoro-beta-D-glycero-hex-2- enopyranose-4-ulosyl)uracil as potential anticancer/antiviral agent.
Nucleosides, nucleotides & nucleic acids 20010101
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Structure-activity relationship of ligands of uracil phosphoribosyltransferase from Toxoplasma gondii.
Biochemical pharmacology 19940817
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Synthesis, structure, and antitumor and antiviral activities of a series of 5-halouridine cyclic 3',5'-monophosphates.
Journal of medicinal chemistry 19860401
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Interaction of monoclonal antibodies directed against bromodeoxyuridine with pyrimidine bases, nucleosides, and DNA.
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