1849-54-3 | 3-Hydroxypyridine-4-carboxaldehyde

Packsize	Purity	Availability	Price	Discounted Price
50mg	98%	in stock	$9.00	$6.00
100mg	98%	in stock	$14.00	$10.00
250mg	98%	in stock	$17.00	$12.00
1g	98%	in stock	$44.00	$31.00
5g	98%	in stock	$219.00	$154.00
10g	98%	in stock	$393.00	$276.00
25g	98%	in stock	$771.00	$540.00

Description

• Catalog Number: AD32554
• Chemical Name: 3-Hydroxypyridine-4-carboxaldehyde
• CAS Number: 1849-54-3
• Molecular Formula: C6H5NO2
• Molecular Weight: 123.1094
• MDL Number: MFCD01318565
• SMILES: O=Cc1ccncc1O

Computed Properties

• Complexity: 105
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 0.5

Upstream Synthesis Route

3-Hydroxypyridine-4-carboxaldehyde, also known as 4-Pyridinecarboxaldehyde-3-ol, is a versatile chemical compound widely used in chemical synthesis. Its primary application lies in its role as a key intermediate in the production of various pharmaceuticals, agrochemicals, and fine chemicals.In chemical synthesis, 3-Hydroxypyridine-4-carboxaldehyde serves as a crucial building block for the creation of complex molecules. Its unique structure containing both a hydroxyl group and an aldehyde group allows for a diverse range of reactions and transformations. One common use of this compound is in the synthesis of heterocyclic compounds, which are essential structural motifs in many biologically active molecules.The hydroxyl group in 3-Hydroxypyridine-4-carboxaldehyde enables selective functionalization and allows for the formation of esters, ethers, and other derivatives. The aldehyde group, on the other hand, can participate in various condensation reactions to form carbon-carbon and carbon-heteroatom bonds. Additionally, the presence of the pyridine ring provides aromatic character, contributing to the overall reactivity and properties of the molecule.Overall, 3-Hydroxypyridine-4-carboxaldehyde plays a crucial role in the realm of chemical synthesis, offering chemists a powerful tool for the construction of diverse and complex molecules with valuable applications in pharmaceutical and agrochemical industries.

Literature

• NMR studies of novel Schiff bases derived from L-alpha-amino methyl esters and 3-hydroxypyridin-4-carboxaldehyde.

  Magnetic resonance in chemistry : MRC 20081001

• Syntheses and structural studies of Schiff bases involving hydrogen bonds.

  Molecules (Basel, Switzerland) 20060621