18546-37-7 | 2-Deoxy-l-erythro-pentopyranose

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$15.00	$11.00
5g	98%	in stock	$48.00	$34.00
10g	98%	in stock	$95.00	$67.00
25g	98%	in stock	$204.00	$143.00

Description

• Catalog Number: AD64377
• Chemical Name: 2-Deoxy-l-erythro-pentopyranose
• CAS Number: 18546-37-7
• Molecular Formula: C5H10O4
• Molecular Weight: 134.1305
• MDL Number: MFCD00132941
• SMILES: O[C@@H]([C@H](CO)O)CC=O

Computed Properties

• Complexity: 83
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 2
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 4
• XLogP3: -2.3

Literature

• 2-deoxyribose deprives cultured astrocytes of their glutathione.

  Neurochemical research 20101101

• [Influence of the thymidine phosphorylase (platelet-derived endothelial cell growth factor) on tumor angiogenesis. Catalytic activity of enzyme inhibitors].

  Postepy biochemii 20100101

• 2-Deoxy-D-ribose, a downstream mediator of thymidine phosphorylase, regulates tumor angiogenesis and progression.

  Anti-cancer agents in medicinal chemistry 20090201

• 2-Deoxy-L-ribose inhibits the invasion of thymidine phosphorylase-overexpressing tumors by suppressing matrix metalloproteinase-9.

  International journal of cancer 20061001

• The role of thymidine phosphorylase, an angiogenic enzyme, in tumor progression.

  Cancer science 20041101

• Inhibition of metastasis of tumor cells overexpressing thymidine phosphorylase by 2-deoxy-L-ribose.

  Cancer research 20040301

• Suppression of thymidine phosphorylase-mediated angiogenesis and tumor growth by 2-deoxy-L-ribose.

  Cancer research 20020515

• Molecular basis for the inhibition of hypoxia-induced apoptosis by 2-deoxy-D-ribose.

  Biochemical and biophysical research communications 20020308