188116-07-6 | Awd 131-138

Packsize	Purity	Availability	Price	Discounted Price
1mg	97%	in stock	$22.00	$15.00
5mg	97%	in stock	$45.00	$31.00
10mg	97%	in stock	$65.00	$45.00
25mg	97%	in stock	$99.00	$69.00
50mg	97%	in stock	$149.00	$104.00

Description

• Catalog Number: AB14757
• Chemical Name: Awd 131-138
• CAS Number: 188116-07-6
• Molecular Formula: C13H14ClN3O2
• Molecular Weight: 279.7222
• MDL Number: MFCD18450225
• SMILES: O=C1N=C(CN1c1ccc(cc1)Cl)N1CCOCC1

Computed Properties

• Complexity: 374
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 19
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• XLogP3: 1.2

Literature

• Anticonvulsant activity and tolerance of ELB138 in dogs with epilepsy: a clinical pilot study.

  Veterinary journal (London, England : 1997) 20060701

• Synthesis, pharmacology, and structure-activity relationships of novel imidazolones and pyrrolones as modulators of GABAA receptors.

  Journal of medicinal chemistry 20060323

• Anticonvulsant efficacy of the low-affinity partial benzodiazepine receptor agonist ELB 138 in a dog seizure model and in epileptic dogs with spontaneously recurrent seizures.

  Epilepsia 20041001

• Evaluation of the novel antiepileptic drug, AWD 131-138, for benzodiazepine-like discriminative stimulus and reinforcing effects in squirrel monkeys.

  European journal of pharmacology 20030404

• [Identity and physicochemical properties of 1-(4-chlorophenyl)-4-morpholino-imidazolin-2-one, AWD 131-138].

  Die Pharmazie 20010601