188591-46-0 | Gsk3787

Packsize	Purity	Availability	Price	Discounted Price
1mg	95%	in stock	$27.00	$19.00
5mg	95%	in stock	$61.00	$43.00
10mg	95%	in stock	$94.00	$66.00
25mg	95%	in stock	$206.00	$144.00
50mg	95%	in stock	$218.00	$153.00

Description

• Catalog Number: AB15184
• Chemical Name: Gsk3787
• CAS Number: 188591-46-0
• Molecular Formula: C15H12ClF3N2O3S
• Molecular Weight: 392.7806
• MDL Number: MFCD00099612
• SMILES: Clc1ccc(cc1)C(=O)NCCS(=O)(=O)c1ccc(cn1)C(F)(F)F

Computed Properties

• Complexity: 557
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 25
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 5
• XLogP3: 2.9

Literature

• Identification of potent Yes1 kinase inhibitors using a library screening approach.

  Bioorganic & medicinal chemistry letters 20130801

• Skin-targeted inhibition of PPAR β/δ by selective antagonists to treat PPAR β/δ-mediated psoriasis-like skin disease in vivo.

  PloS one 20120101

• Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-beta/delta antagonist GSK3787.

  Molecular pharmacology 20100901

• Identification and characterization of 4-chloro-N-(2-{[5-trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide (GSK3787), a selective and irreversible peroxisome proliferator-activated receptor delta (PPARdelta) antagonist.

  Journal of medicinal chemistry 20100225