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Cilengitide in newly diagnosed glioblastoma: biomarker expression and outcome.
Oncotarget 20160322
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Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial.
The Lancet. Oncology 20140901
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Integrin inhibitor cilengitide for the treatment of glioblastoma: a brief overview of current clinical results.
Anticancer research 20121001
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Cilengitide in bevacizumab-refractory high-grade glioma: two case reports and critical review of the literature.
Anti-cancer drugs 20120801
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A randomized phase II study of cilengitide (EMD 121974) in patients with metastatic melanoma.
Melanoma research 20120801
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Cyclic RGD peptidomimetics containing bifunctional diketopiperazine scaffolds as new potent integrin ligands.
Chemistry (Weinheim an der Bergstrasse, Germany) 20120514
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Is there a world beyond bevacizumab in targeting angiogenesis in glioblastoma?
Expert opinion on investigational drugs 20120501
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A phase I study of continuous infusion cilengitide in patients with solid tumors.
Investigational new drugs 20120401
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Phase II study of cilengitide (EMD 121974, NSC 707544) in patients with non-metastatic castration resistant prostate cancer, NCI-6735. A study by the DOD/PCF prostate cancer clinical trials consortium.
Investigational new drugs 20120401
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Peptides for cell-selective drug delivery.
Trends in pharmacological sciences 20120401
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Anti-angiogenic approaches to malignant gliomas.
Current cancer drug targets 20120301
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Cilengitide in patients with recurrent glioblastoma: the results of NABTC 03-02, a phase II trial with measures of treatment delivery.
Journal of neuro-oncology 20120101
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Antiangiogenic therapy for patients with recurrent and newly diagnosed malignant gliomas.
Journal of oncology 20120101
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Targeting the tumor microenvironment: focus on angiogenesis.
Journal of oncology 20120101
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Integrin-mediated cell-matrix interaction in physiological and pathological blood vessel formation.
Journal of oncology 20120101
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Integrin inhibitors as a therapeutic agent for ovarian cancer.
Journal of oncology 20120101
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Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy.
Theranostics 20120101
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Deciphering the Multifaceted Relationship between Oncolytic Viruses and Natural Killer Cells.
Advances in virology 20120101
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MGMT promoter methylation in gliomas-assessment by pyrosequencing and quantitative methylation-specific PCR.
Journal of translational medicine 20120101
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Methodology for Anti-Gene Anti-IGF-I Therapy of Malignant Tumours.
Chemotherapy research and practice 20120101
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RGD-conjugated gold nanorods induce radiosensitization in melanoma cancer cells by downregulating α(v)β₃ expression.
International journal of nanomedicine 20120101
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Fibronectin matrix-mediated cohesion suppresses invasion of prostate cancer cells.
BMC cancer 20120101
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Prostaglandins in cancer cell adhesion, migration, and invasion.
International journal of cell biology 20120101
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Integrins and their extracellular matrix ligands in lymphangiogenesis and lymph node metastasis.
International journal of cell biology 20120101
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Novel therapies in glioblastoma.
Neurology research international 20120101
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Current trends in targeted therapies for glioblastoma multiforme.
Neurology research international 20120101
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Vitronectin increases vascular permeability by promoting VE-cadherin internalization at cell junctions.
PloS one 20120101
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Combination of RGD compound and low-dose paclitaxel induces apoptosis in human glioblastoma cells.
PloS one 20120101
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Current knowledge on pancreatic cancer.
Frontiers in oncology 20120101
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Cilengitide treatment for malignant glioma: current status and future direction.
Neurologia medico-chirurgica 20120101
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Cilengitide (EMD 121974, NSC 707544) in asymptomatic metastatic castration resistant prostate cancer patients: a randomized phase II trial by the prostate cancer clinical trials consortium.
Investigational new drugs 20111201
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Cilengitide: a prototypic integrin inhibitor for the treatment of glioblastoma and other malignancies.
Genes & cancer 20111201
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Cilengitide inhibits metastatic bone colonization in a nude rat model.
Oncology reports 20111001
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Treatment of high-grade glioma in children and adolescents.
Neuro-oncology 20111001
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Bulletin du cancer 20111001
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Increasing αvβ3 selectivity of the anti-angiogenic drug cilengitide by N-methylation.
Angewandte Chemie (International ed. in English) 20110926
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Impact of therapy on quality of life, neurocognitive function and their correlates in glioblastoma multiforme: a review.
Journal of neuro-oncology 20110901
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Cilengitide induces autophagy-mediated cell death in glioma cells.
Neuro-oncology 20110801
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Advances in MRI assessment of gliomas and response to anti-VEGF therapy.
Current neurology and neuroscience reports 20110601
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Radiation-induced modifications of the tumor microenvironment promote metastasis.
Bulletin du cancer 20110601
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Pathway inhibition: emerging molecular targets for treating glioblastoma.
Neuro-oncology 20110601
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Phase I/II trial of cilengitide with cetuximab, cisplatin and 5-fluorouracil in recurrent and/or metastatic squamous cell cancer of the head and neck: findings of the phase I part.
British journal of cancer 20110524
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Cilengitide inhibits progression of experimental breast cancer bone metastases as imaged noninvasively using VCT, MRI and DCE-MRI in a longitudinal in vivo study.
International journal of cancer 20110515
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Isthmin exerts pro-survival and death-promoting effect on endothelial cells through alphavbeta5 integrin depending on its physical state.
Cell death & disease 20110501
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Recurrent high-grade glioma: a diagnostic and therapeutic challenge.
Expert review of neurotherapeutics 20110401
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Glioblastoma: changing expectations?
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20110401
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Cilengitide: an RGD pentapeptide ανβ3 and ανβ5 integrin inhibitor in development for glioblastoma and other malignancies.
Future oncology (London, England) 20110301
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Angiogenesis and invasion in glioma.
Brain tumor pathology 20110201
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Antiangiogenic agents in the treatment of recurrent or newly diagnosed glioblastoma: analysis of single-agent and combined modality approaches.
Radiation oncology (London, England) 20110101
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Evaluation of the anti-angiogenic properties of the new selective αVβ3 integrin antagonist RGDechiHCit.
Journal of translational medicine 20110101
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Vaccines targeting the neovasculature of tumors.
Vascular cell 20110101
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Integrin αvβ3-targeted gold nanoshells augment tumor vasculature-specific imaging and therapy.
International journal of nanomedicine 20110101
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A meta-analysis of gemcitabine containing chemotherapy for locally advanced and metastatic pancreatic adenocarcinoma.
Journal of hematology & oncology 20110101
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Evaluation of treatment response of cilengitide in an experimental model of breast cancer bone metastasis using dynamic PET with 18F-FDG.
Hellenic journal of nuclear medicine 20110101
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Why integrin as a primary target for imaging and therapy.
Theranostics 20110101
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Integrin targeted therapeutics.
Theranostics 20110101
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Integrin targeted delivery of chemotherapeutics.
Theranostics 20110101
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Investigation of In Vivo Targeting Kinetics of α(v)β(3)-Specific Superparamagnetic Nanoprobes by Time-Resolved MRI.
Theranostics 20110101
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Therapeutic targets for bone metastases in breast cancer.
Breast cancer research : BCR 20110101
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Bevacizumab for the treatment of recurrent glioblastoma.
Clinical Medicine Insights. Oncology 20110101
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Novel diagnostic and therapeutic approaches to malignant glioma.
Swiss medical weekly 20110101
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Identification of novel SNPs in glioblastoma using targeted resequencing.
PloS one 20110101
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Current pharmaceutical design 20110101
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Interaction of tumor cells with the microenvironment.
Cell communication and signaling : CCS 20110101
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Targeting ανβ3 and ανβ5 inhibits photon-induced hypermigration of malignant glioma cells.
Radiation oncology (London, England) 20110101
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Integrins and their ligands in rheumatoid arthritis.
Arthritis research & therapy 20110101
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Inhibitors of Glioma Growth that Reveal the Tumour to the Immune System.
Clinical Medicine Insights. Oncology 20110101
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New agents targeting angiogenesis in glioblastoma.
Chemotherapy research and practice 20110101
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Molecular targets for radiation oncology in prostate cancer.
Frontiers in oncology 20110101
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Combined modality approaches in the management of adult glioblastoma.
Frontiers in oncology 20110101
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Anti-angiogenic therapies for children with cancer.
Current cancer drug targets 20101201
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2010: neuro-oncology is moving!
Current opinion in neurology 20101201
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Cilengitide: the first anti-angiogenic small molecule drug candidate design, synthesis and clinical evaluation.
Anti-cancer agents in medicinal chemistry 20101201
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What role should cilengitide have in the treatment of glioblastoma?
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American Association for Cancer Research Genetics and Biology of Brain Cancers 2009, December 13-15, 2009, San Diego, CA.
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Emerging targets in osteoporosis disease modification.
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Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma.
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Integrins as target: first phase III trial launches, but questions remain.
Journal of the National Cancer Institute 20100519
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Survival of patients with newly diagnosed glioblastoma treated with radiation and temozolomide in research studies in the United States.
Clinical cancer research : an official journal of the American Association for Cancer Research 20100415
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Interplay between cell adhesion and growth factor receptors: from the plasma membrane to the endosomes.
Cell and tissue research 20100101
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Integrins in cancer: biological implications and therapeutic opportunities.
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BCNU for recurrent glioblastoma multiforme: efficacy, toxicity and prognostic factors.
BMC cancer 20100101
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Antiangiogenic therapy and mechanisms of tumor resistance in malignant glioma.
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Vicrostatin - an anti-invasive multi-integrin targeting chimeric disintegrin with tumor anti-angiogenic and pro-apoptotic activities.
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The potential of nanomedicine therapies to treat neovascular disease in the retina.
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Identification of novel short chain 4-substituted indoles as potent alphavbeta3 antagonist using structure-based drug design.
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Integrin alpha v beta 3 antagonist Cilengitide enhances efficacy of radiotherapy in endothelial cell and non-small-cell lung cancer models.
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Phase II evaluations of cilengitide in asymptomatic patients with androgen-independent prostate cancer: scientific rationale and study design.
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