1937-19-5 | Aminoguanidine hydrochloride

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$6.00	$4.00
10g	98%	in stock	$7.00	$5.00
25g	98%	in stock	$15.00	$11.00
100g	98%	in stock	$56.00	$39.00
500g	98%	in stock	$71.00	$50.00

Description

• Catalog Number: AI66029
• Chemical Name: Aminoguanidine hydrochloride
• CAS Number: 1937-19-5
• Molecular Formula: CH7ClN4
• Molecular Weight: 110.5461
• MDL Number: MFCD00039074
• SMILES: NN=C(N)N.Cl
• NSC Number: 760398

Computed Properties

• Complexity: 41.6
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 6
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 4

Literature

• NF-κB-iNOS-COX2-TNF α inflammatory signaling pathway plays an important role in methotrexate induced small intestinal injury in rats.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20180801

• Evidence for the involvement of TNF-α, IL-1β and IL-10 in the antinociceptive and anti-inflammatory effects of indole-3-guanylhydrazone hydrochloride, an aromatic aminoguanidine, in rodents.

  Chemico-biological interactions 20180425

• A positive feedback loop between nitric oxide and amyloid β (1-42) accelerates mitochondrial damage in human lens epithelial cells.

  Toxicology 20170415

• Aminoguanidine alleviated MMA-induced impairment of cognitive ability in rats by downregulating oxidative stress and inflammatory reaction.

  Neurotoxicology 20170301

• Arsenic toxicity induced endothelial dysfunction and dementia: pharmacological interdiction by histone deacetylase and inducible nitric oxide synthase inhibitors.

  Toxicology and applied pharmacology 20131115

• Effect of 2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione, isolated from Averrhoa carambola L. (Oxalidaceae) roots, on advanced glycation end-product-mediated renal injury in type 2 diabetic KKAy mice.

  Toxicology letters 20130510

• Hypoxia in the diabetic kidney is independent of advanced glycation end-products.

  Advances in experimental medicine and biology 20130101

• Attenuation of acute nitrogen mustard-induced lung injury, inflammation and fibrogenesis by a nitric oxide synthase inhibitor.

  Toxicology and applied pharmacology 20121215

• The regulatory role of the NO/cGMP signal transduction cascade during larval attachment and metamorphosis of the barnacle Balanus (=Amphibalanus) amphitrite.

  The Journal of experimental biology 20121101

• The involvement of nitric oxide in the anti-seizure effect of acute atorvastatin treatment in mice.

  Neurological research 20121101

• Effect of curcumin and quercetin on lysosomal enzyme activities in streptozotocin-induced diabetic rats.

  Clinical nutrition (Edinburgh, Scotland) 20121001

• Role of peroxynitrite in sepsis-induced acute kidney injury in an experimental model of sepsis in rats.

  Shock (Augusta, Ga.) 20121001

• A computational model of cellular response to modulated radiation fields.

  International journal of radiation oncology, biology, physics 20120901

• Synthesis of 2-(1,5-diaryl-1,4-pentadien-3-ylidene)-hydrazinecarboximidamide hydrochloride catalyzed by p-dodecylbenzenesulfonic acid in aqueous media under ultrasound irradiation.

  Ultrasonics sonochemistry 20120901

• Effect of cervical spinal cord electrical stimulation on nitric oxide levels in brain and dermal tissues: an evaluation using by real-time nitric oxide measurement.

  Acta neurochirurgica 20120901

• Comparative evaluation of the effect of tricyclic antidepressants on inducible nitric oxide synthase expression in neuropathic pain model.

  Nitric oxide : biology and chemistry 20120815

• Delayed myocardial preconditioning induced by cobalt chloride in the rat: HIF-1α and iNOS involvement.

  Fundamental & clinical pharmacology 20120801

• Possible involvement of PPAR-gamma receptor and nitric oxide pathway in the anticonvulsant effect of acute pioglitazone on pentylenetetrazole-induced seizures in mice.

  Epilepsy research 20120801

• Effect of selective inhibition of renal inducible nitric oxide synthase on renal blood flow and function in experimental hyperdynamic sepsis.

  Critical care medicine 20120801

• Genistein prevents isoproterenol-induced cardiac hypertrophy in rats.

  Canadian journal of physiology and pharmacology 20120801

• Acute kidney injury with sepsis: is nitric oxide a friend, foe, both, or neither?

  Critical care medicine 20120801

• [Effect of aminoguanidine on spinal cord edema of acute spinal cord injury in rats].

  Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20120801

• In vivo participation of nitric oxide in hyperproliferative epidermal phenomena in mice.

  European journal of pharmacology 20120715

• High-glucose and S100B stimulate glutamate uptake in C6 glioma cells.

  Neurochemical research 20120701

• Nitric oxide is responsible for oxidative skin injury and modulation of cell proliferation after 24 hours of UVB exposures.

  Free radical research 20120701

• Hypertension induces brain β-amyloid accumulation, cognitive impairment, and memory deterioration through activation of receptor for advanced glycation end products in brain vasculature.

  Hypertension (Dallas, Tex. : 1979) 20120701

• The effects of aminoguanidine on retinopathy in STZ-induced diabetic rats.

  Bioorganic & medicinal chemistry letters 20120701

• Selective and nonselective neuronal NOS inhibitors impair cognitive function in the three panel runway and passive avoidance tasks in rats.

  Pharmacology, biochemistry, and behavior 20120601

• Pharmacophore modeling, virtual screening and 3D-QSAR studies of 5-tetrahydroquinolinylidine aminoguanidine derivatives as sodium hydrogen exchanger inhibitors.

  Bioorganic & medicinal chemistry letters 20120601

• [The effect of aminoguanidine on osteoclast in periodontal tissues during the rotation movement of teeth in rabbits].

  Shanghai kou qiang yi xue = Shanghai journal of stomatology 20120601

• Anti-fibrotic cardio protective efficacy of aminoguanidine against streptozotocin induced cardiac fibrosis and high glucose induced collagen up regulation in cardiac fibroblasts.

  Chemico-biological interactions 20120530

• Inhibition of macrophage oxidative stress prevents the reduction of ABCA-1 transporter induced by advanced glycated albumin.

  Lipids 20120501

• [The different roles of the spinal protein nNOS and iNOS in morphine naloxone-precipitated withdrawal response].

  Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20120501

• Inhibition of advanced glycation end-product formation on eye lens protein by rutin.

  The British journal of nutrition 20120401

• Synthesis of nitrogen-rich mesoporous carbon nitride with tunable pores, band gaps and nitrogen content from a single aminoguanidine precursor.

  ChemSusChem 20120401

• Chronic administration of atorvastatin induced anti-convulsant effects in mice: the role of nitric oxide.

  Epilepsy & behavior : E&B 20120401

• Cynarin-rich sunflower (Helianthus annuus) sprouts possess both antiglycative and antioxidant activities.

  Journal of agricultural and food chemistry 20120328

• High- and low-spin Fe(III) complexes of various AGE inhibitors.

  The journal of physical chemistry. A 20120322

• Endogenous formation of Nε-(carboxymethyl)lysine is increased in fatty livers and induces inflammatory markers in an in vitro model of hepatic steatosis.

  Journal of hepatology 20120301

• Antinociceptive effect of VSL#3 on visceral hypersensitivity in a rat model of irritable bowel syndrome: a possible action through nitric oxide pathway and enhance barrier function.

  Molecular and cellular biochemistry 20120301

• Cytokine-induced human islet cell death in vitro correlates with a persistently high phosphorylation of STAT-1, but not with NF-κB activation.

  Biochemical and biophysical research communications 20120224

• Differential effects of substrate-analogue inhibitors on nitric oxide synthase dimerization.

  Biochemical and biophysical research communications 20120203

• Effects of inducible nitric oxide synthase blockade within the periaqueductal gray on cardiovascular responses during mechanical, heat, and cold nociception.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20120201

• Mechanisms and interventions in peritoneal fibrosis.

  Clinical and experimental nephrology 20120201

• Aminoguanidine down-regulates the expression of mreB-like protein in Bacillus subtilis.

  Current microbiology 20120201

• COX-2 and survivin reduction may play a role in berberine-induced apoptosis in human ductal breast epithelial tumor cell line.

  Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20120201

• Aminoguanidine and curcumin attenuated tumor necrosis factor (TNF)-α-induced oxidative stress, colitis and hepatotoxicity in mice.

  International immunopharmacology 20120101

• Aminoguanidine normalizes ET-1-induced aortic contraction in type 2 diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats by suppressing Jab1-mediated increase in ET(A)-receptor expression.

  Peptides 20120101

• The roles of angiotensin II receptors in the portosystemic collaterals of portal hypertensive and cirrhotic rats.

  Journal of vascular research 20120101

• The protective effect of aminoguanidine on doxorubicin-induced nephropathy in rats.

  Journal of biochemical and molecular toxicology 20120101

• [Altered intestinal P-glycoprotein expression levels affect pharmacodynamics under diabetic condition].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20120101

• [Influence of environmental factors on the generation of nitric oxide in the roots of etiolated pea seedlings].

  Prikladnaia biokhimiia i mikrobiologiia 20120101

• Hepatic nitrosative stress in experimental diabetes.

  Journal of diabetes and its complications 20120101

• A novel source of methylglyoxal and glyoxal in retina: implications for age-related macular degeneration.

  PloS one 20120101

• Reactions of aminoguanidine with α-dicarbonyl compounds studied by electrospray ionization mass spectrometry.

  European journal of mass spectrometry (Chichester, England) 20120101

• Methylglyoxal accumulation in arterial walls causes vascular contractile dysfunction in spontaneously hypertensive rats.

  Journal of pharmacological sciences 20120101

• Antidepressant-like activity of ellagic acid in unstressed and acute immobilization-induced stressed mice.

  Pharmacological reports : PR 20120101

• Controversial behavior of aminoguanidine in the presence of either reducing sugars or soluble glycated bovine serum albumin.

  Carbohydrate research 20111227

• Effects of induced diabetes and the administration of aminoguanidine in the biomechanical retention of implants: a study in rats.

  Journal of periodontal research 20111201

• The relative efficacy of aminoguanidine and pentoxifylline in modulating endotoxin-induced cardiac stress.

  Cell biochemistry and function 20111201

• Inducible nitric oxide synthase inhibitor aminoguanidine, differently affects Morris water maze tasks of ovariectomized and naïve female rats.

  Acta physiologica Hungarica 20111201

• iNOS-derived nitric oxide stimulates osteoclast activity and alveolar bone loss in ligature-induced periodontitis in rats.

  Journal of periodontology 20111101

• The protective mechanism for the blood-brain barrier induced by aminoguanidine in surgical brain injury in rats.

  Cellular and molecular neurobiology 20111101

• Inhibition of advanced glycation end products by aminoguanidine restores mast cell numbers and reactivity in alloxan-diabetic rats.

  European journal of pharmacology 20111101

• Antidepressant-like effect of pioglitazone in the forced swimming test in mice: the role of PPAR-gamma receptor and nitric oxide pathway.

  Behavioural brain research 20111031

• Application of accelerator mass spectrometry to macromolecules: preclinical pharmacokinetic studies on a polybisphosphonate.

  Rapid communications in mass spectrometry : RCM 20110915

• AGE formation blockade with aminoguanidine does not ameliorate chronic allograft nephropathy.

  Life sciences 20110912

• Nitric oxide involvement in consolidation, but not retrieval phase of cognitive performance enhanced by atorvastatin in mice.

  European journal of pharmacology 20110901

• Glycation induction and antiglycation activity of skin care ingredients on living human skin explants.

  International journal of cosmetic science 20110801

• Rescuing hepatocytes from iron-catalyzed oxidative stress using vitamins B1 and B6.

  Toxicology in vitro : an international journal published in association with BIBRA 20110801

• The role of nonenzymatic glycation and carbonyls in collagen cross-linking for the treatment of keratoconus.

  Investigative ophthalmology & visual science 20110801

• The effects of long-term storage of human red blood cells on the glutathione synthesis rate and steady-state concentration.

  Transfusion 20110701

• Tumor necrosis factor alpha pathways develops liver apoptosis in type 1 diabetes mellitus.

  Molecular immunology 20110701

• Intraperitoneal aminoguanidine improves sciatic nerve ischemia-reperfusion injury in male sprague-dawley rats.

  Cellular and molecular neurobiology 20110701

• Effects of aminoguanidine and vitamin C on collagen type IV in diabetic nephropathy rats.

  Endocrine 20110601

• Effect of aminoguanidine in sperm DNA fragmentation in varicocelized rats: role of nitric oxide.

  Reproductive sciences (Thousand Oaks, Calif.) 20110601

• Use of aminoguanidine, a selective inducible nitric oxide synthase inhibitor, to evaluate the role of nitric oxide in periapical inflammation.

  Journal of oral science 20110601

• Involvement of nitric oxide pathways in neurogenic pulmonary edema induced by vagotomy.

  Clinics (Sao Paulo, Brazil) 20110601

• Vascular expression, activity and function of indoleamine 2,3-dioxygenase-1 following cerebral ischaemia-reperfusion in mice.

  Naunyn-Schmiedeberg's archives of pharmacology 20110501

• Atorvastatin improved scopolamine-induced impairment in memory acquisition in mice: involvement of nitric oxide.

  Brain research 20110422

• Inducible nitric oxide synthase-mediated alteration of mitochondrial OPA1 expression in ocular hypertensive rats.

  Investigative ophthalmology & visual science 20110401

• Out-of-field cell survival following exposure to intensity-modulated radiation fields.

  International journal of radiation oncology, biology, physics 20110401

• [Nitric oxide synthase-mediated alteration of intestinal P-glycoprotein under hyperglycemic stress].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110401

• Effect of aminoguanidine on the conjunctival histamine and nitrite levels in experimental conjunctivitis.

  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20110401

• Regulation of inducible nitric oxide synthase expression in bovine ovarian granulosa cells.

  Molecular and cellular endocrinology 20110330

• The role of NOS in the impairment of spatial memory and damaged neurons in rats injected with amyloid beta 25-35 into the temporal cortex.

  Pharmacology, biochemistry, and behavior 20110301

• Aminoguanidine administration ameliorates hippocampal damage after middle cerebral artery occlusion in rat.

  Neurochemical research 20110301

• Argirein alleviates diabetic nephropathy through attenuating NADPH oxidase, Cx43, and PERK in renal tissue.

  Naunyn-Schmiedeberg's archives of pharmacology 20110301

• Competition of NO synthases and arginase in the airways hyperreactivity.

  General physiology and biophysics 20110301

• Pyridoxine restores endothelial cell function in high glucose.

  Metabolic syndrome and related disorders 20110201

• Intravenous injection of mesenteric lymph produced during hemorrhagic shock decreases RBC deformability in the rat.

  The Journal of trauma 20110201

• Role of nitric oxide-synthase and cyclooxygenase/lipooxygenase systems in development of experimental ulcerative colitis.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20110201

• [Effect of topical application of aminoguanidine cream on skin tissue of rats with diabetes].

  Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20110201

• Neonatal rat microglia derived from different brain regions have distinct activation responses.

  Neuron glia biology 20110201

• Nitric oxide synthase inhibitors protect cerebellar Purkinje cells from zinc-induced cell loss in adult rat.

  Journal of chemical neuroanatomy 20110101

• Aminoguanidine improves epididymal sperm parameters in varicocelized rats.

  Urologia internationalis 20110101

• Optimization of filaggrin expression and processing in cultured rat keratinocytes.

  Journal of dermatological science 20110101

• Aminoguanidine potentiates the hepatoprotective effect of silymarin in CCL4 treated rats.

  Annals of hepatology 20110101

• Protective effect of aminoguanidine against cyclophosphamide-induced oxidative stress and renal damage in rats.

  Redox report : communications in free radical research 20110101

• Lipid-induced peroxidation in the intestine is involved in glucose homeostasis imbalance in mice.

  PloS one 20110101

• Role of inducible nitric oxide synthase pathway on methotrexate-induced intestinal mucositis in rodents.

  BMC gastroenterology 20110101

• Decreased expression of intestinal P-glycoprotein increases the analgesic effects of oral morphine in a streptozotocin-induced diabetic mouse model.

  Drug metabolism and pharmacokinetics 20110101

• Aminoguanidine and N-acetyl-cysteine supress oxidative and nitrosative stress in EAE rat brains.

  Redox report : communications in free radical research 20110101

• Aminoguanidine, a selective nitric oxide synthase inhibitor, attenuates cyclophosphamide-induced renal damage by inhibiting protein nitration and poly(ADP-Ribose) polymerase activation.

  Chemotherapy 20110101

• Effect of aminoguanidine on ischemia/reperfusion injury in rat small intestine.

  Biological & pharmaceutical bulletin 20110101

• [The liver and kidneys biochemical indices at the experimental pancreatitis in case of the administration of nitric oxide synthesis modulators and recombinant superoxide dismutase].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20110101

• Resorcylidene aminoguanidine (RAG) improves cardiac mitochondrial bioenergetics impaired by hyperglycaemia in a model of experimental diabetes.

  International journal of molecular sciences 20110101

• Antifungal agents. Part 5: synthesis and antifungal activities of aminoguanidine derivatives of N-arylsulfonyl-3-acylindoles.

  Bioorganic & medicinal chemistry letters 20101215

• Repeated agmatine treatment attenuates nicotine sensitization in mice: modulation by alpha2-adrenoceptors.

  Behavioural brain research 20101201

• Methylglyoxal scavengers attenuate endothelial dysfunction induced by methylglyoxal and high concentrations of glucose.

  British journal of pharmacology 20101201

• Inhibition of inducible nitric oxide synthase reverses the loss of functional hyperemia in diabetic retinopathy.

  Glia 20101201

• Sevoflurane-induced preconditioning: impact of protocol and aprotinin administration on infarct size and endothelial nitric-oxide synthase phosphorylation in the rat heart in vivo.

  Anesthesiology 20101201

• Effect of inhibitors of inducible and neuronal NO synthases on the development of audiogenic stress-induced damage in Krushinskii-Molodkina rats.

  Bulletin of experimental biology and medicine 20101201

• Increase nitric oxide synthase activity in parotid glands from rats with experimental periodontitis.

  Oral diseases 20101101

• Effect of sodium nitroprusside, a nitric oxide donor, and aminoguanidine, a nitric oxide synthase inhibitor, on in vitro development of buffalo (Bubalus bubalis) embryos.

  Reproduction in domestic animals = Zuchthygiene 20101001

• Aggregation and self assembly of non-enzymatic glycation of collagen in the presence of amino guanidine and aspirin: an in vitro study.

  International journal of biological macromolecules 20101001

• Dual effect of nitric oxide on uterine prostaglandin synthesis in a murine model of preterm labour.

  British journal of pharmacology 20101001

• GABAergic and nitriergic modulation by curcumin for its antianxiety-like activity in mice.

  Brain research 20100917

• Does accumulation of advanced glycation end products contribute to the aging phenotype?

  The journals of gerontology. Series A, Biological sciences and medical sciences 20100901

• Ralstonia solanacearum induces soluble amine-oxidase activity in Solanum torvum stem calli.

  Plant physiology and biochemistry : PPB 20100901

• Aminoguanidine inhibition of iNOS activity ameliorates cerebral vasospasm after subarachnoid hemorrhage in rabbits via restoration of dysfunctional endothelial cells.

  Journal of the neurological sciences 20100815

• Thioredoxin glycation: A novel posttranslational modification that inhibits its antioxidant and organ protective actions.

  Free radical biology & medicine 20100801

• Involvement of nitric oxide in maneb- and paraquat-induced Parkinson's disease phenotype in mouse: is there any link with lipid peroxidation?

  Neurochemical research 20100801

• Carbonylation of myosin heavy chains in rat heart during diabetes.

  Biochemical pharmacology 20100715

• Agmatine, an endogenous imidazoline receptor ligand modulates ethanol anxiolysis and withdrawal anxiety in rats.

  European journal of pharmacology 20100710

• Upregulation of AT1R and iNOS in the rostral ventrolateral medulla (RVLM) is essential for the sympathetic hyperactivity and hypertension in the 2K-1C Wistar rat model.

  American journal of hypertension 20100701

• Photoprotection by 1alpha,25-dihydroxyvitamin D and analogs: further studies on mechanisms and implications for UV-damage.

  The Journal of steroid biochemistry and molecular biology 20100701

• Role of oxidative stress and nitric oxide in the protective effects of alpha-lipoic acid and aminoguanidine against isoniazid-rifampicin-induced hepatotoxicity in rats.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100701

• Dynamics of intracellular superoxide and NO content in human endotheliocytes and carcinoma cells after treatment with NO synthase inhibitors.

  Bulletin of experimental biology and medicine 20100701

• The effect of aminoguanidine on compression spinal cord injury in rats.

  Brain research 20100625

• Diabetes depresses synaptic transmission in sympathetic ganglia by inactivating nAChRs through a conserved intracellular cysteine residue.

  Neuron 20100624

• Fasting-induced intestinal apoptosis is mediated by inducible nitric oxide synthase and interferon-{gamma} in rat.

  American journal of physiology. Gastrointestinal and liver physiology 20100601

• Potential new therapeutic agents for diabetic kidney disease.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20100501

• NaHS ameliorates diabetic vascular injury by correcting depressed connexin 43 and 40 in the vasculature in streptozotocin-injected rats.

  The Journal of pharmacy and pharmacology 20100501

• Nitric oxide synthase inhibitors protect cholinergic neurons against AlCl3 excitotoxicity in the rat brain.

  Brain research bulletin 20100405

• L-arginine enhances nitrative stress and exacerbates tumor necrosis factor-alpha toxicity to human endothelial cells in culture: prevention by propofol.

  Journal of cardiovascular pharmacology 20100401

• Activated macrophages as a novel determinant of tumor cell radioresponse: the role of nitric oxide-mediated inhibition of cellular respiration and oxygen sparing.

  International journal of radiation oncology, biology, physics 20100401

• Differential effects of nitric oxide synthase inhibitors on anxiety in unstressed and stressed mice.

  Indian journal of experimental biology 20100401

• 2-Deoxy-D-ribose induces cellular damage by increasing oxidative stress and protein glycation in a pancreatic beta-cell line.

  Metabolism: clinical and experimental 20100301

• Inhibition of inducible nitric oxide controls pathogen load and brain damage by enhancing phagocytosis of Escherichia coli K1 in neonatal meningitis.

  The American journal of pathology 20100301

• Neuroprotective actions of aminoguanidine involve reduced the activation of calpain and caspase-3 in a rat model of stroke.

  Neurochemistry international 20100301

• Central NO-cGMP pathway in thermoregulation and survival rate during polymicrobial sepsis.

  Canadian journal of physiology and pharmacology 20100201

• Short- and long-term modulation of microvascular responses in streptozotocin-induced diabetic rats by glycosylated products.

  Journal of diabetes and its complications 20100101

• Hyperglycemic oxoaldehyde, glyoxal, causes barrier dysfunction, cytoskeletal alterations, and inhibition of angiogenesis in vascular endothelial cells: aminoguanidine protection.

  Molecular and cellular biochemistry 20100101

• Efficient sonochemical synthesis of novel 3,5-diaryl-4,5-dihydro-1H-pyrazole-1-carboximidamides.

  Ultrasonics sonochemistry 20100101

• Aminoguanidine administered during the induction of oral tolerance alters the systemic response of the tolerised rats.

  Cellular immunology 20100101

• In situ gelable glycation-resistant hydrogels composed of gelatin and oxidized alginate.

  Journal of biomaterials science. Polymer edition 20100101

• [Effect of L-arginine and aminoguanidine on morphological characteristics of the lymphocyte plasma membranes during experimental diabetes mellitus].

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20100101

• Advanced glycation end products in extracellular matrix proteins contribute to the failure of sensory nerve regeneration in diabetes.

  Diabetes 20091201

• Influence of pyridoxylidene aminoguanidine on biomarkers of the oxidative stress and selected metabolic parameters of rats with diabetes mellitus.

  General physiology and biophysics 20091201

• Involvement of NO-cGMP pathway in anti-anxiety effect of aminoguanidine in stressed mice.

  Progress in neuro-psychopharmacology & biological psychiatry 20091113

• Aggravation of cold-restraint stress-induced gastric lesions in adjuvant arthritic rats: pathogenic role of inducible and endothelial nitric oxide.

  Journal of pharmacological sciences 20091101

• [Nitric oxide synthase (NOS) expression and nitric oxide (NO) content in the skeletal muscles in transverse process syndrome of the 3rd lumbar vertebra of model rats treated with acupotomology therapy].

  Zhongguo gu shang = China journal of orthopaedics and traumatology 20091101

• [The effects of aminoguanidine inhalation on bleomycin-induced fibrosis in lungs].

  Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20091101

• Nitric oxide regulates lung carcinoma cell anoikis through inhibition of ubiquitin-proteasomal degradation of caveolin-1.

  The Journal of biological chemistry 20091009

• Anti-cataractogenic effect of curcumin and aminoguanidine against selenium-induced oxidative stress in the eye lens of Wistar rat pups: An in vitro study using isolated lens.

  Chemico-biological interactions 20091007

• Metformin restores impaired HDL-mediated cholesterol efflux due to glycation.

  Atherosclerosis 20091001

• Inhibitory effects of aminoguanidine on thyroid follicular carcinoma development in inflamed capsular regions of rats treated with sulfadimethoxine after N-bis(2-hydroxypropyl)nitrosamine-initiation.

  Cancer science 20091001

• Synthesis and bioactivity of substituted indan-1-ylideneaminoguanidine derivatives.

  European journal of medicinal chemistry 20090901

• Diabetes impairs hippocampal function via advanced glycation end product mediated new neuron generation in animals with diabetes-related depression.

  Toxicological sciences : an official journal of the Society of Toxicology 20090901

• Pharmacological inhibition of inducible nitric oxide synthase attenuates the development of seizures in mice.

  Nitric oxide : biology and chemistry 20090901

• Impaired transcription factor interplay in addition to advanced glycation end products suppress podocalyxin expression in high glucose-treated human podocytes.

  American journal of physiology. Renal physiology 20090901

• [Inhalation of aminoguanidine prevents the up-regulation of connective tissue growth factor in fibrotic lungs of rats].

  Sheng li xue bao : [Acta physiologica Sinica] 20090825

• Isoproterenol disperses distribution of NADPH oxidase, MMP-9, and pPKCepsilon in the heart, which are mitigated by endothelin receptor antagonist CPU0213.

  Acta pharmacologica Sinica 20090801

• The molecular mechanism of aminoguanidine-mediated reduction on the brain edema after surgical brain injury in rats.

  Brain research 20090728

• Nitric oxide mediates lung vascular permeability and lymph-borne IL-6 after an intestinal ischemic insult.

  Shock (Augusta, Ga.) 20090701

• Suppression of retinal neovascularization by the iNOS inhibitor aminoguanidine in mice of oxygen-induced retinopathy.

  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20090701

• Effects of vitamin E and sodium selenate on impaired contractile activity by bacterial lipopolysaccharide in the rat vas deferens.

  Naunyn-Schmiedeberg's archives of pharmacology 20090701

• Combination of dexamethasone and aminoguanidine reduces secondary damage in compression spinal cord injury.

  Cellular and molecular neurobiology 20090701

• Effects of NO/L-arginine pathway on gallbladder contractility in bile duct ligated guinea pigs.

  The Journal of surgical research 20090701

• Aminoguanidine, selective nitric oxide synthase inhibitor, ameliorates cyclophosphamide-induced hemorrhagic cystitis by inhibiting protein nitration and PARS activation.

  Urology 20090601

• Combustion smoke exposure induces up-regulated expression of vascular endothelial growth factor, aquaporin 4, nitric oxide synthases and vascular permeability in the retina of adult rats.

  Neuroscience 20090519

• Aminoguanidine alleviates radiation-induced small-bowel damage through its antioxidant effect.

  International journal of radiation oncology, biology, physics 20090501

• Role of inducible nitric oxide synthase in rostral ventrolateral medulla in blood pressure regulation in spontaneously hypertensive rats.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20090501

• Blocking systemic nitric oxide production alters neuronal activation in brain structures involved in cardiovascular regulation during polymicrobial sepsis.

  Neuroscience letters 20090410

• Effect of inhibition of synthesis of inducible nitric oxide synthase-derived nitric oxide by aminoguanidine on the in vitro maturation of oocyte-cumulus complexes of cattle.

  Animal reproduction science 20090401

• Antinociceptive effect of chronic lithium on visceral hypersensitivity in a rat model of diarrhea-predominant irritable bowel syndrome: The role of nitric oxide pathway.

  Journal of gastroenterology and hepatology 20090401

• Pharmacologic intervention targeting glycolytic-related pathways protects against retinal injury due to ischemia and reperfusion.

  Proteomics 20090401

• Aminoguanidine impedes human pancreatic tumor growth and metastasis development in nude mice.

  World journal of gastroenterology 20090307

• Nicotine attenuates iNOS expression and contributes to neuroprotection in a compressive model of spinal cord injury.

  Journal of neuroscience research 20090301

• The role of RAGE in aminoguanidine-induced suppression of venous intimal hyperplasia in diabetic rats.

  Annals of vascular surgery 20090301

• Concurrent supplementation of arginine, vitamin E, and vitamin C improve cardiopulmonary performance in broilers chickens.

  Poultry science 20090301

• Prenatal lipopolysaccharide increases postnatal intestinal injury in a rat model of necrotizing enterocolitis.

  Journal of pediatric gastroenterology and nutrition 20090301

• Potential prophylactic role of aminoguanidine in diabetic retinopathy and nephropathy in experimental animals.

  Acta pharmaceutica (Zagreb, Croatia) 20090301

• 7-nitroindazole, but not L-NAME or aminoguanidine, attenuates anaphylactic hypotension in conscious rats.

  Shock (Augusta, Ga.) 20090201

• Effects of aminoguanidine, an inhibitor of inducible nitric oxide synthase, on nitric oxide production and its metabolites in healthy control subjects, healthy smokers, and COPD patients.

  Chest 20090201

• High-performance liquid chromatographic determination of creatine kinase activity influenced by methylglyoxal.

  Biomedical chromatography : BMC 20090201

• Nitric oxide synthase inhibition by pentacycloundecane conjugates of aminoguanidine and tryptamine.

  Archiv der Pharmazie 20090201

• Graft preconditioning with low-dose tacrolimus (FK506) and nitric oxide inhibitor aminoguanidine (AGH) reduces ischemia/reperfusion injury after liver transplantation in the rat.

  Archives of pharmacal research 20090201

• Synthesis, characterization and properties of nitrogen-rich salts of trinitrophloroglucinol.

  Journal of hazardous materials 20090130

• Preventive effect of aminoguanidine compared to vitamin E and C on cisplatin-induced nephrotoxicity in rats.

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20090101

• The effect of iNOS inhibitors and hyperbaric oxygen treatment in a rat model of experimental colitis.

  Digestive diseases and sciences 20090101

• Protective effect of aminoguanidine against oxidative stress and bladder injury in cyclophosphamide-induced hemorrhagic cystitis in rat.

  Cell biochemistry and function 20090101

• Posttreatment with aminoguanidine attenuates renal ischemia/reperfusion injury in rats.

  Renal failure 20090101

• The breakdown of preformed peritoneal advanced glycation end products by intraperitoneal alagebrium.

  Journal of Korean medical science 20090101

• Effects of aminoguanidine on tissue oxidative stress induced by hindlimb unloading in rats.

  Annals of clinical and laboratory science 20090101

• Effect of nitric oxide/cyclic guanosine mono-phosphate pathway on gallbladder relaxant response in bile duct-ligated guinea pigs.

  European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20090101

• The effect of nitric oxide synthase inhibitors on the development of analgesic tolerance to dipyrone in mice.

  The International journal of neuroscience 20090101

• [Using NO-synthase inhibitors derived from L-arginine for preventing acute experimental lung edema development in mice].

  Eksperimental'naia i klinicheskaia farmakologiia 20090101

• Hippocampal alterations in rats submitted to streptozotocin-induced dementia model are prevented by aminoguanidine.

  Journal of Alzheimer's disease : JAD 20090101

• Blockade of advanced glycation end product formation attenuates bleomycin-induced pulmonary fibrosis in rats.

  Respiratory research 20090101

• Increased neuronal nitric oxide synthase activity in retinal neurons in early diabetic retinopathy.

  Molecular vision 20090101

• Peroxynitrite plays a key role in glomerular lesions in diabetic rats.

  Journal of nephrology 20090101

• Aminoguanidine inhibits aortic hydrogen peroxide production, VSMC NOX activity and hypercontractility in diabetic mice.

  Cardiovascular diabetology 20090101

• Effects of nitric oxide in mucociliary transport.

  Brazilian journal of otorhinolaryngology 20090101

• Role of aminoguanidine in brain protection in surgical brain injury in rat.

  Neuroscience letters 20081226

• Signaling cascade that mediates endothelial nitric oxide synthase activation induced by atrial natriuretic peptide.

  Regulatory peptides 20081129

• Inducible nitric oxide synthase expression and cardiomyocyte dysfunction during sustained moderate ischemia in pigs.

  Circulation research 20081107

• Activation of inducible NOS in peripheral vessels and outcomes in heart failure patients.

  Journal of cardiac failure 20081101

• Determining conditions for nitric oxide synthesis in Caco-2 cells using Taguchi and factorial experimental designs.

  Analytical biochemistry 20081015

• Ozone oxidative preconditioning protects the rat kidney from reperfusion injury: the role of nitric oxide.

  The Journal of surgical research 20081001

• Effect of bacterial lipopolysaccharide on ischemic damage in the rat retina.

  Investigative ophthalmology & visual science 20081001

• The involvement of nitric oxide in maneb- and paraquat-induced oxidative stress in rat polymorphonuclear leukocytes.

  Free radical research 20081001

• Nitric oxide associated with iNOS expression inhibits acetylcholinesterase activity and induces memory impairment during acute hypobaric hypoxia.

  Brain research 20080916

• Effects of N(omega)-nitro-L-arginine methyl ester and aminoguanidine on lipopolysaccharide-induced airway hyperresponsiveness in guinea pigs.

  Chinese medical journal 20080905

• A novel immunosuppressive pathway involving peroxynitrite-mediated [corrected] nitration of platelet antigens within antigen-presenting cells.

  Transfusion 20080901

• Inhibitory activities of prenylated flavonoids from Sophora flavescens against aldose reductase and generation of advanced glycation endproducts.

  The Journal of pharmacy and pharmacology 20080901

• Liver tissue inducible nitric oxide synthase (iNOS) expression and lipid peroxidation in experimental hepatic ischemia reperfusion injury stimulated with lipopolysaccharide: the role of aminoguanidine.

  The Journal of surgical research 20080801

• The effects of diabetes and aminoguanidine treatment on endothelial function in a primate model of type 1 diabetes.

  American journal of primatology 20080801

• Suppression of grasshopper sound production by nitric oxide-releasing neurons of the central complex.

  Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20080801

• Protective effects of melatonin and aminoguanidine on the cornea in streptozotocin-induced diabetic rats.

  Cornea 20080801

• Nitric oxide plays a key role in the platelet-activating factor-induced enhancement of resistance against systemic candidiasis.

  Immunology 20080701

• The endothelin receptor antagonist CPU0213 is more effective than aminoguanidine to attenuate isoproterenol-induced vascular abnormality by suppressing overexpression of NADPH oxidase [correction of oxidas], ETA, ETB, and MMP9 in the vasculature.

  Journal of cardiovascular pharmacology 20080701

• Isoflurane preconditioning reduces mouse microglial activation and injury induced by lipopolysaccharide and interferon-gamma.

  Neuroscience 20080626

• Nitric oxide signaling pathway in the anti-convulsant effect of adenosine against pentylenetetrazol-induced seizure threshold in mice.

  European journal of pharmacology 20080610

• Distribution of NOS isoforms in a porcine endotoxin shock model.

  Shock (Augusta, Ga.) 20080601

• Hyperbaric oxygenation reduces overexpression of c-Fos and oxidative stress in the brain stem of experimental endotoxemic rats.

  Intensive care medicine 20080601

• Aminoguanidine prevents the impairment of cardiac pumping mechanics in rats with streptozotocin and nicotinamide-induced type 2 diabetes.

  British journal of pharmacology 20080601

• Hdm2 and nitric oxide radicals contribute to the p53-dependent radioadaptive response.

  International journal of radiation oncology, biology, physics 20080601

• Diabetic cardiomyopathy: how much does it depend on AGE?

  British journal of pharmacology 20080601

• Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein A-I.

  Diabetologia 20080601

• Reconstructed skin modified by glycation of the dermal equivalent as a model for skin aging and its potential use to evaluate anti-glycation molecules.

  Experimental gerontology 20080601

• The effects of arginine and selective inducible nitric oxide synthase inhibitor on pathophysiology of sepsis in a CLP model.

  The Journal of surgical research 20080515

• Neuroprotective effect of aminoguanidine on iron-induced neurotoxicity.

  Brain research bulletin 20080515

• The pyridoxamine action on Amadori compounds: A reexamination of its scavenging capacity and chelating effect.

  Bioorganic & medicinal chemistry 20080515

• [Effect of a selective inducible nitric oxide synthase inhibitor on cell growth in human colorectal cancer Lovo cell line].

  Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20080501

• The effect of selective inhibition of inducible nitric oxide synthase on cytochrome P450 after liver transplantation in a rat model.

  Transplantation proceedings 20080501

• Nitric oxide down-regulates the expression of organic cation transporters (OCT) 1 and 2 in rat kidney during endotoxemia.

  European journal of pharmacology 20080428

• Designing the polyamine pharmacophore: influence of N-substituents on the transport behavior of polyamine conjugates.

  Journal of medicinal chemistry 20080424

• Synergistic interaction between meloxicam and aminoguanidine in formalin-induced nociception in mice.

  European journal of pain (London, England) 20080401

• Vascular leakage induced by exposure to arsenic via increased production of NO, hydroxyl radical and peroxynitrite.

  Microvascular research 20080401

• Deficiency of mitogen-activated protein kinase phosphatase-1 results in iNOS-mediated hypotension in response to low-dose endotoxin.

  American journal of physiology. Heart and circulatory physiology 20080401

• The effect of N-nitro-L-arginine and aminoguanidine treatment on changes in constitutive and inducible nitric oxide synthases in the spinal cord after sciatic nerve transection.

  International journal of molecular medicine 20080401

• Role of maltol in advanced glycation end products and free radicals: in-vitro and in-vivo studies.

  The Journal of pharmacy and pharmacology 20080401

• Prevention of chronic stress-induced depression-like behavior by inducible nitric oxide inhibitor.

  Neuroscience letters 20080305

• Inhibitors of advanced glycation end-products prevent loss of enteric neuronal nitric oxide synthase in diabetic rats.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20080301

• Glycation inhibitory activity and the identification of an active compound in Plantago asiatica extract.

  Phytotherapy research : PTR 20080301

• Effect of aminoguanidine on lipopolysaccharide-induced changes in rat liver transporters and transcription factors.

  Biological & pharmaceutical bulletin 20080301

• [Effect of aminoguanidine on hemodynamics and nitrogen monoxide in hemorrhagic shock in rabbit].

  Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20080301

• Nuclear factor-kappaB activation and postischemic inflammation are suppressed in CD36-null mice after middle cerebral artery occlusion.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080213

• Alterations in spontaneous contractions of rat ileum and jejunum after peritonitis.

  European journal of pharmacology 20080202

• Reversal of iron-induced nephrotoxicity in rats by molsidomine, a nitric oxide donor.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080201

• iNOS activity is critical for the clearance of Burkholderia mallei from infected RAW 264.7 murine macrophages.

  Cellular microbiology 20080201

• Prevention of HIF-1 activation and iNOS gene targeting by low-dose cadmium results in loss of myocardial hypoxic preconditioning in the rat.

  American journal of physiology. Heart and circulatory physiology 20080201

• [Advanced glycation end products and their receptors elevate the activity of endothelin-1 in rat cavernosum].

  Zhonghua nan ke xue = National journal of andrology 20080201

• Effects of morphine during Mycobacterium tuberculosis H37Rv infection in mice.

  Life sciences 20080130

• Glucose release as a response to glucagon in rat hepatocyte culture: involvement of NO signaling.

  Physiological research 20080101

• Prenatal exposure to endotoxin in rats attenuates the allergic airways eosinophil infiltration in the adult offspring: role of inducible nitric oxide synthase activation.

  Pulmonary pharmacology & therapeutics 20080101

• Effect of aminoguanidine on post-ischemic damage in rodent model of stroke.

  Pakistan journal of pharmaceutical sciences 20080101

• Hydrogen peroxide generated by copper amine oxidase is involved in abscisic acid-induced stomatal closure in Vicia faba.

  Journal of experimental botany 20080101

• [Peculiarities of L-arginine metabolism in the blood leukocytes in experimental diabetes mellitus].

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20080101

• Effects of selective iNOS inhibition in sepsis: evaluation of lung tissue damage and blood gases.

  International surgery 20080101

• Effect of NO-synthase and arginase inhibition in airway hyperreactivity.

  Bratislavske lekarske listy 20080101

• Aminoguanidine ameliorates radiation-induced oxidative lung damage in rats.

  Clinical and investigative medicine. Medecine clinique et experimentale 20080101

• Effect of carnosine, aminoguanidine, and aspirin drops on the prevention of cataracts in diabetic rats.

  Molecular vision 20080101

• Intestinal endotoxemia plays a central role in development of hepatopulmonary syndrome in a cirrhotic rat model induced by multiple pathogenic factors.

  World journal of gastroenterology 20071221

• Protective effect of inducible nitric oxide synthase inhibitor on pancreas transplantation in rats.

  World journal of gastroenterology 20071207

• Adverse effects of excessive nitric oxide on cytochrome c oxidase in lenses of hereditary cataract UPL rats.

  Toxicology 20071205

• Lymphatic-borne IL-1beta and the inducible isoform of nitric oxide synthase trigger the bronchial hyporesponsiveness after intestinal ischema/reperfusion in rats.

  Shock (Augusta, Ga.) 20071201

• Interferon-gamma and lipopolysaccharide stimulation increases matrix metalloproteinase-9 expression and enhances invasion activity in ras/myc-transformed serum-free mouse embryo cells.

  Cell biology international 20071201

• Upregulated endothelin system in diabetic vascular dysfunction and early retinopathy is reversed by CPU0213 and total triterpene acids from Fructus Corni.

  Clinical and experimental pharmacology & physiology 20071201

• Effect of aminoguanidine on visual evoked potentials (VEPs), antioxidant status and lipid peroxidation in rats exposed to chronic restraint stress.

  Brain research 20071201

• Intracerebroventricular injection of neuronal and inducible nitric oxide synthase inhibitors does not influence febrile response in rats during turpentine abscess.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20071201

• Monocyte chemoattractant protein-1 and nitric oxide promote adipogenesis in a model that mimics obesity.

  Obesity (Silver Spring, Md.) 20071201

• Aminoguanidine delays the replicative senescence of human diploid fibroblasts.

  Chinese medical journal 20071120

• Involvement of nitric oxide in spatial memory deficits in status epilepticus rats.

  Neurochemical research 20071101

• Aminoguanidine produces beneficial haemodynamic effects in a canine model of acute pulmonary thromboembolism.

  Acta physiologica (Oxford, England) 20071101

• Trichloroethylene induce nitric oxide production and nitric oxide synthase mRNA expression in cultured normal human epidermal keratinocytes.

  Toxicology 20071008

• Methylglyoxal induces advanced glycation end product (AGEs) formation and dysfunction of PDGF receptor-beta: implications for diabetic atherosclerosis.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20071001

• Carboxylic acid drug-induced DNA nicking in HEK293 cells expressing human UDP-glucuronosyltransferases: role of acyl glucuronide metabolites and glycation pathways.

  Chemical research in toxicology 20071001

• Influence of simultaneous inhibition of cyclooxygenase-2 and inducible nitric oxide synthase in experimental colitis in rats.

  Inflammopharmacology 20071001

• Effect of aminoguanidine on post-ischemic brain edema in transient model of focal cerebral ischemia.

  Brain research 20070919

• Effects of manipulating the nitric oxide/cyclic GMP pathway on bovine oocyte meiotic resumption in vitro.

  Theriogenology 20070915

• Nitric oxide radicals choreograph a radioadaptive response.

  Cancer research 20070915

• The role of nitric oxide in diabetes-induced changes of morphine tolerance in rats.

  European journal of pharmacology 20070910

• Propofol-induced vascular permeability change is related to the nitric oxide signaling pathway and occludin phosphorylation.

  Journal of biomedical science 20070901

• Thapsigargin, a selective inhibitor of sarco-endoplasmic reticulum Ca2+ -ATPases, modulates nitric oxide production and cell death of primary rat hepatocytes in culture.

  Cell biology and toxicology 20070901

• Evidence for in vivo scavenging by aminoguanidine of formaldehyde produced via semicarbazide-sensitive amine oxidase-mediated deamination.

  The Journal of pharmacology and experimental therapeutics 20070901

• In vitro pharmacological study of femoral artery vascular reactivity after inferior canine hindlimb ischemia/reperfusion: effects of in vivo nitric oxide blocker infusion.

  Annals of vascular surgery 20070901

• Protective effect of Liuwei Dihuang decoction on early diabetic nephropathy induced by streptozotocin via modulating ET-ROS axis and matrix metalloproteinase activity in rats.

  The Journal of pharmacy and pharmacology 20070901

• Intracerebroventricular injection of neuronal and inducible nitric oxide synthase inhibitors attenuates fever due to LPS in rats.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20070901

• Inhibition of inducible nitric oxide synthase ameliorates lung injury in rats after gut ischemia-reperfusion.

  The Journal of trauma 20070901

• Lung toxicity of nitrogen mustard may be mediated by nitric oxide and peroxynitrite in rats.

  Research in veterinary science 20070801

• iNOS-derived NO and nox2-derived superoxide confer tolerance to excitotoxic brain injury through peroxynitrite.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070801

• Spermine and spermidine mediate protection against oxidative damage caused by hydrogen peroxide.

  Amino acids 20070801

• Effect of an inducible nitric oxide synthase inhibitor on differential flow-exhaled nitric oxide in asthmatic patients and healthy volunteers.

  Chest 20070801

• Advanced glycation end products decrease mesangial cell MMP-7: a role in matrix accumulation in diabetic nephropathy?

  Kidney international 20070801

• Advanced glycation of apolipoprotein A-I impairs its anti-atherogenic properties.

  Diabetologia 20070801

• Evidence for an enhancement of excitatory transmission in adult CNS by Wnt signaling pathway modulation.

  Molecular and cellular neurosciences 20070801

• Higher accumulation of gamma-aminobutyric acid induced by salt stress through stimulating the activity of diamine oxidases in Glycine max (L.) Merr. roots.

  Plant physiology and biochemistry : PPB 20070801

• Chk2 kinase is required for methylglyoxal-induced G2/M cell-cycle checkpoint arrest: implication of cell-cycle checkpoint regulation in diabetic oxidative stress signaling.

  Genes to cells : devoted to molecular & cellular mechanisms 20070801

• Methylglyoxal impairs glucose metabolism and leads to energy depletion in neuronal cells--protection by carbonyl scavengers.

  Neurobiology of aging 20070701

• Ameliorative effect of combined administration of inducible nitric oxide synthase inhibitor with cyclooxygenase-2 inhibitors in neuropathic pain in rats.

  European journal of pain (London, England) 20070701

• Renal fibrosis and glomerulosclerosis in a new mouse model of diabetic nephropathy and its regression by bone morphogenic protein-7 and advanced glycation end product inhibitors.

  Diabetes 20070701

• Differential signalling pathways involved in cholinoceptor-dependent stimulation of nitric oxide isoforms in dental pulp.

  International endodontic journal 20070701

• Synthesis, spectroscopic and X-ray characterization of a copper(II) complex with the Schiff base derived from pyridoxal and aminoguanidine: NMR spectral studies of the ligand.

  Journal of inorganic biochemistry 20070701

• Prolonged treatment with aminoguanidine strongly inhibits adipocyte semicarbazide-sensitive amine oxidase and slightly reduces fat deposition in obese Zucker rats.

  Pharmacological research 20070701

• Identification of a novel Cys2/His2-type zinc-finger protein as a component of a spermine-signaling pathway in tobacco.

  Journal of plant physiology 20070601

• Effect of nitric oxide on phagocytic activity of lipopolysaccharide-induced macrophages: possible role of exogenous L-arginine.

  Cell biology international 20070601

• Aminoguanidine prevents fructose-induced deterioration in left ventricular-arterial coupling in Wistar rats.

  British journal of pharmacology 20070601

• L-Carnitine inhibits protein glycation in vitro and in vivo: evidence for a role in diabetic management.

  Acta diabetologica 20070601

• Attenuation of hypertension development by aminoguanidine in spontaneously hypertensive rats: role of methylglyoxal.

  American journal of hypertension 20070601

• The role of nitric oxide in radiation damage.

  Biological & pharmaceutical bulletin 20070601

• Eugenosedin-A amelioration of lipopolysaccharide-induced up-regulation of p38 MAPK, inducible nitric oxide synthase and cyclooxygenase-2.

  The Journal of pharmacy and pharmacology 20070601

• Role of nitric oxide and reduced glutathione in the protective effects of aminoguanidine, gadolinium chloride and oleanolic acid against acetaminophen-induced hepatic and renal damage.

  Toxicology 20070505

• Participation of the inducible nitric oxide synthase on atrial natriuretic peptide plasma concentration during endotoxemic shock.

  Regulatory peptides 20070503

• The involvement of matrix metalloproteinases 2 and 9 in rat retinal ischemia.

  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20070501

• Nitric oxide differentially regulates renal ATP-binding cassette transporters during endotoxemia.

  Pflugers Archiv : European journal of physiology 20070501

• Role of nitric oxide on pathogenesis of 5-fluorouracil induced experimental oral mucositis in hamster.

  Cancer chemotherapy and pharmacology 20070401

• Responsiveness to inhaled NO in isolated-perfused lungs from endotoxin-challenged rats is dependent on endogenous nitrite/nitrate synthesis.

  European journal of anaesthesiology 20070401

• Different roles of nitric oxide synthase isoforms in cardiopulmonary resuscitation in pigs.

  Resuscitation 20070401

• Structural and functional recovery elicited by combined putrescine and aminoguanidine treatment after aspirative lesion of the fimbria-fornix and overlying cortex in the adult rat.

  The European journal of neuroscience 20070401

• Effect of aminoguanidine treatment on diabetes-induced changes in the myenteric plexus of rat ileum.

  Autonomic neuroscience : basic & clinical 20070330

• Nitric oxide inhibits interleukin-12 p40 through p38 MAPK-mediated regulation of calmodulin and c-rel.

  Free radical biology & medicine 20070301

• Beneficial effect of Corni Fructus, a constituent of Hachimi-jio-gan, on advanced glycation end-product-mediated renal injury in Streptozotocin-treated diabetic rats.

  Biological & pharmaceutical bulletin 20070301

• Antagonic effect of the inhibition of inducible nitric oxide on the mortality of mice acutely infected with Escherichia coli and Bacteroides fragilis.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20070301

• Gender-specific neuroprotection by 2-iminobiotin after hypoxia-ischemia in the neonatal rat via a nitric oxide independent pathway.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070201

• Interactions between nitric oxide and corticosterone in the regulation of progenitor cell proliferation in the dentate gyrus of the adult rat.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070201

• Participation of iNOS-derived NO in hypothalamic activation and vasopressin release during polymicrobial sepsis.

  Journal of neuroimmunology 20070201

• Nitric oxide in prepubertal rat ovary contribution of the ganglionic nitric oxide synthase system via superior ovarian nerve.

  Neuro endocrinology letters 20070201

• [Synthesis and bioactivity of N- [4- ( benzimidazole-2-thio) phenyl] -N'-alkyl guanidine derivatives].

  Yao xue xue bao = Acta pharmaceutica Sinica 20070201

• Intracellular NO concentration and its changes in carcinoma cells and cultured human endotheliocytes under the influence of inhibitors and inductors of nitric oxide synthases.

  Bulletin of experimental biology and medicine 20070201

• Differential influence of iNOS and nNOS inhibitors on rostral ventrolateral medullary mediated cardiovascular control in conscious rats.

  Autonomic neuroscience : basic & clinical 20070130

• Role of endogenous nitric oxide (NO) and NO synthases in healing of indomethacin-induced intestinal ulcers in rats.

  Life sciences 20070102

• Dimethylarginine dimethylaminohydrolase inhibition and asymmetric dimethylarginine accumulation contribute to endothelial dysfunction in rats exposed to glycosylated protein: effects of aminoguanidine.

  Atherosclerosis 20070101

• The effect of aminoguanidine against cholestatic liver injury in rats.

  Cell biochemistry and function 20070101

• The role of adrenergic agonists on glycogenolysis in rat hepatocyte cultures and possible involvement of NO.

  Physiological research 20070101

• Effect of early decrease in the lesion size on late brain tissue loss, synaptophysin expression and functionality after a focal brain lesion in rats.

  Neurochemistry international 20070101

• Effects of a nitric oxide synthase Type II inhibitor on compound action potential thresholds in experimental endolymphatic hydrops.

  Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20070101

• Interferon-gamma induced nitric oxide mediates in vitro neuronal damage by Trypanosoma cruzi-infected macrophages.

  Neurobiology of disease 20070101

• Modulatory effect of nitric oxide on mast cells during induction of dextran sulfate sodium colitis.

  Digestive diseases and sciences 20070101

• Decreased formation of advanced glycation end-products in peritoneal fluid by carnosine and related peptides.

  Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20070101

• Effect of certain immunosuppressants on non-specific immunity cells in murine corneal grafts: study on early phases after transplantation.

  Physiological research 20070101

• Retinal ischemia and reperfusion causes capillary degeneration: similarities to diabetes.

  Investigative ophthalmology & visual science 20070101

• Effect of magnesium deficiency on intracellular ATP levels in human lens epithelial cells.

  Biological & pharmaceutical bulletin 20070101

• Nitric oxide and prostaglandin response to group B streptococcal infection in the lung.

  Annals of clinical and laboratory science 20070101

• Nitric oxide does not contribute to inflammation-induced hypoferremia in humans.

  Acta haematologica 20070101

• Role of nitric oxide in the expression of hepatic vascular stress genes in response to sepsis.

  Nitric oxide : biology and chemistry 20070101

• The role of resuscitation promoting factors in pathogenesis and reactivation of Mycobacterium tuberculosis during intra-peritoneal infection in mice.

  BMC infectious diseases 20070101

• [Neuroprotection in glaucoma].

  Annales Academiae Medicae Stetinensis 20070101

• Molecular mechanism of emotional fever--the role of nitric oxide.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20061101

• Roles of COX-2 and iNOS in the bony repair of the injured growth plate cartilage.

  Journal of cellular biochemistry 20061001

• Involvement of endogenous opioid peptides and nitric oxide in the blunted chronotropic and inotropic responses to beta-adrenergic stimulation in cirrhotic rats.

  Fundamental & clinical pharmacology 20061001

• Renal damage in rats induced by myocardial ischemia/reperfusion: Role of nitric oxide.

  International journal of urology : official journal of the Japanese Urological Association 20061001

• Role of endogenous nitric oxide in mucosal defense of inflamed rat stomach following iodoacetamide treatment.

  Life sciences 20060913

• Effect of pyridoxylidene aminoguanidine on human diploid cells B-HEF-2: in vitro cytotoxicity test and cytogenetic analysis.

  Toxicology in vitro : an international journal published in association with BIBRA 20060901

• Synthesis of mono- and symmetrical di-N-hydroxy- and N-aminoguanidines.

  The Journal of organic chemistry 20060901

• Nitric oxide production by hepatocytes contributes to the inhibitory effect of endotoxin on insulin-like growth factor I gene expression.

  The Journal of endocrinology 20060901

• The role of adenosine in the early respiratory and cardiovascular changes evoked by chronic hypoxia in the rat.

  The Journal of physiology 20060815

• Macrophage populations and cardiac sympathetic denervation during L-NAME-induced hypertension in rats.

  Histology and histopathology 20060801

• Novel therapeutic strategies for reducing arterial stiffness.

  British journal of pharmacology 20060801

• Improved cardiovascular function with aminoguanidine in DOCA-salt hypertensive rats.

  British journal of pharmacology 20060801

• Pathogenic role of endothelial nitric oxide synthase (eNOS/NOS-III) in cerulein-induced rat acute pancreatitis.

  Digestive diseases and sciences 20060801

• Gender-specificity of delayed preconditioning by isoflurane in rabbits: potential role of endothelial nitric oxide synthase.

  Anesthesia and analgesia 20060801

• Sigma 1 receptor agonists act as neuroprotective drugs through inhibition of inducible nitric oxide synthase.

  Anesthesia and analgesia 20060801

• Interaction of natural killer cells with Trypanosoma cruzi-infected fibroblasts.

  Clinical and experimental immunology 20060801

• Aminoguanidine prevents arterial stiffening in a new rat model of type 2 diabetes.

  European journal of clinical investigation 20060801

• [Effects of selective iNOS inhibitor aminoguanidine on waveform of blood pressure in rat heat stroke].

  Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20060801

• Involvement of p38 mitogen-activated protein kinase and inducible nitric oxide synthase in apoptotic signaling of murine and human male germ cells after hormone deprivation.

  Molecular endocrinology (Baltimore, Md.) 20060701

• Inhibition of nitric oxide production by aminoguanidine influences the number of Trichinella spiralis parasites in infected 'low responders' (C57BL/6) and 'high responders' (BALB/c) mice.

  Parasitology research 20060701

• Nitric oxide-dependent killing of Cryptococcus neoformans by B-1-derived mononuclear phagocyte.

  Journal of leukocyte biology 20060701

• Attenuation of morphine tolerance and dependence by aminoguanidine in mice.

  European journal of pharmacology 20060701

• Inhibitors of the Maillard reaction and AGE breakers as therapeutics for multiple diseases.

  Drug discovery today 20060701

• Novel alkylpolyaminoguanidines and alkylpolyaminobiguanides with potent antitrypanosomal activity.

  Bioorganic & medicinal chemistry letters 20060615

• Involvement of endogenous nitric oxide in myeloperoxidase mediated benzo(a)pyrene induced polymorphonuclear leukocytes injury.

  Molecular and cellular biochemistry 20060601

• Effect of nitric oxide synthases inhibitors on exogenous irritant-induced bronchial hyper-reactivity in guinea pigs.

  General physiology and biophysics 20060601

• Role of nitric oxide in the local and systemic pathophysiological effects induced by Bothrops asper snake venom in mice.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060601

• Cardiovascular responses and neurotransmitter changes during static muscle contraction following blockade of inducible nitric oxide synthase (iNOS) within the ventrolateral medulla.

  Brain research 20060523

• Immobilization stress causes extra-cellular oxidant-antioxidant imbalance in rats: restoration by L-NAME and vitamin E.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20060501

• The selective inhibition of inducible nitric oxide synthase prevents intestinal ischemia-reperfusion injury in mice.

  Nitric oxide : biology and chemistry 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Effects of COX-2 and iNOS inhibitors alone or in combination with olfactory ensheathing cell grafts after spinal cord injury.

  Spine 20060501

• Bioactivation of carboxylic acid compounds by UDP-Glucuronosyltransferases to DNA-damaging intermediates: role of glycoxidation and oxidative stress in genotoxicity.

  Chemical research in toxicology 20060501

• DNA damage by free radical production by aminoguanidine.

  Annals of the New York Academy of Sciences 20060501

• Aminoguanidine prevents arterial stiffening and cardiac hypertrophy in streptozotocin-induced diabetes in rats.

  British journal of pharmacology 20060401

• The effects of tempol, 3-aminobenzamide and nitric oxide synthase inhibitors on acoustic injury of the mouse cochlea.

  Hearing research 20060401

• Beneficial role of aminoguanidine on acute cardiomyopathy related to doxorubicin-treatment.

  Molecular and cellular biochemistry 20060401

• Effects of inducible nitric oxide synthase inhibitors on asthma depending on administration schedule.

  Free radical biology & medicine 20060315

• Inducible nitric oxide synthase contributes to gender differences in ischemic brain injury.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20060301

• Inducible nitric oxide synthase inhibitors abolished histological protection by late ischemic preconditioning in rat retina.

  Experimental eye research 20060301

• Aminoguanidine and metformin prevent the reduced rate of HDL-mediated cell cholesterol efflux induced by formation of advanced glycation end products.

  The international journal of biochemistry & cell biology 20060301

• Upregulation of vascular inducible nitric oxide synthase mediates the hypotensive effect of ethanol in conscious female rats.

  Journal of applied physiology (Bethesda, Md. : 1985) 20060301

• Aminoguanidine inhibits caspase-3 and calpain activation without affecting microglial activation following neonatal transient cerebral ischemia.

  Journal of neurochemistry 20060301

• The breakdown of preformed advanced glycation end products reverses erectile dysfunction in streptozotocin-induced diabetic rats: preventive versus curative treatment.

  The journal of sexual medicine 20060301

• Influence of aminoguanidine, an inhibitor of inducible nitric oxide synthase, on the pulmonary hypertensive response to microparticle injections in broilers.

  Poultry science 20060301

• Pulmonary hypertension triggered by lipopolysaccharide in ascites-susceptible and -resistant broilers is not amplified by aminoguanidine, a specific inhibitor of inducible nitric oxide synthase.

  Poultry science 20060301

• 5'-Adenosinephosphosulphate reductase (CysH) protects Mycobacterium tuberculosis against free radicals during chronic infection phase in mice.

  Molecular microbiology 20060301

• [The changes of advanced glycation end products in a rat liver fibrosis model and the interventional effect of aminoguanidin].

  Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20060301

• Aminoguanidine prevented impairment of blood antioxidant system in insulin-dependent diabetic rats.

  Life sciences 20060216

• Synergistic anti-inflammatory interaction between meloxicam and aminoguanidine hydrochloride in carrageenan-induced acute inflammation in rats.

  Life sciences 20060202

• Selective inhibition of inducible nitric oxide synthase reduces neurological deficit but not cerebral edema following traumatic brain injury.

  Neuropharmacology 20060201

• Macrophageal/microglial cell activation and cerebral injury induced by excretory-secretory products secreted by Paragonimus westermani.

  Neuroscience research 20060201

• Involvement of nitric oxide pathway in the acute anticonvulsant effect of melatonin in mice.

  Epilepsy research 20060201

• Protamine sulfate causes endothelium-independent vasorelaxation via inducible nitric oxide synthase pathway.

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 20060201

• Transmission electron microscopy and autofluorescence findings in the cornea of diabetic rats treated with aminoguanidine.

  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20060201

• IFN-gamma: regulation of nitric oxide in the P. aeruginosa-infected cornea.

  Ocular immunology and inflammation 20060201

• Evaluation of total plasma nitric oxide concentrations in broilers infused intravenously with sodium nitrite, lipopolysaccharide, aminoguanidine, and sodium nitroprusside.

  Poultry science 20060201

• [Effects of aminoguanidine on the lung injury induced by the total hepatic ischemia-reperfusion in rats].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20060201

• [Effects of L-arginine and aminoguanidine on the endotoxin induced lung injury in rats].

  Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20060201

• Effect of polyamine homologation on the transport and biological properties of heterocyclic amidines.

  Journal of medicinal chemistry 20060112

• Activity and expression of semicarbazide-sensitive benzylamine oxidase in a rodent model of diabetes: interactive effects with methylamine and alpha-aminoguanidine.

  European journal of pharmacology 20060104

• Effects of aminoguanidine against renal ischaemia-reperfusion injury in rats.

  Cell biochemistry and function 20060101

• Protective effect of aminoguanidine against oxidative stress in an experimental peritoneal adhesion model in rats.

  Cell biochemistry and function 20060101

• Substrate specificity of rabbit aldehyde oxidase for nitroguanidine and nitromethylene neonicotinoid insecticides.

  Chemical research in toxicology 20060101

• uPAR expression under hypoxic conditions depends on iNOS modulated ERK phosphorylation in the MDA-MB-231 breast carcinoma cell line.

  Cell research 20060101

• The effect of aminoguanidine on blood and tissue lipid peroxidation in jaundiced rats with endotoxemia induced with LPS.

  Journal of investigative surgery : the official journal of the Academy of Surgical Research 20060101

• Polyamine and aminoguanidine treatments to promote structural and functional recovery in the adult mammalian brain after injury: a brief literature review and preliminary data about their combined administration.

  Journal of physiology, Paris 20060101

• Comparison of FK 506, mycophenolate mofetil, and aminoguanidine effects on delay of corneal allograft rejection in an experimental model of low-risk and high-risk keratoplasty.

  Immunopharmacology and immunotoxicology 20060101

• Experimental endolymphatic hydrops under action of a type II nitric oxide synthase inhibitor: otoacoustic emissions evaluation and electrocochleography.

  Brazilian journal of otorhinolaryngology 20060101

• Protective role of aminoguanidine on gentamicin-induced acute renal failure in rats.

  Acta histochemica 20060101

• Calpain inhibition attenuates iNOS production and midzonal hepatic necrosis in a repeat dose model of endotoxemia in rats.

  Toxicologic pathology 20060101

• [Effects of NO-synthase inhibitors on maturation mouse oocytes in cumulus-oocyte complexes].

  Ontogenez 20060101

• [Effect of aminoguanidine on oxidative modification of proteins in experimental diabetes mellitus in rats].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20060101

• [Influence of free radicals on Trichinella spiralis infection in mice].

  Wiadomosci parazytologiczne 20060101

• 2,4,6-Trinitrotoluene inhibits endothelial nitric oxide synthase activity and elevates blood pressure in rats.

  Archives of toxicology 20051201

• The effects of aminoguanidine on primary and recurrent ocular herpes simplex virus infection.

  Nitric oxide : biology and chemistry 20051201

• Inhibitory effect of inducible nitric oxide synthase inhibitors on DMBA-induced hamster buccal-pouch squamous-cell carcinogenesis.

  Nitric oxide : biology and chemistry 20051201

• Beneficial effects of aminoguanidine on peritoneal microcirculation and tissue remodelling in a rat model of PD.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20051201

• Metabolism of aminoguanidine, diaminoguanidine, and NG-amino-L-arginine by neuronal NO-synthase and covalent alteration of the heme prosthetic group.

  Chemical research in toxicology 20051201

• The effect of inducible nitric oxide synthase inhibitor on microvascular permeability after cerebral ischemia/reperfusion.

  Methods and findings in experimental and clinical pharmacology 20051201

• Light promotes the synthesis of lignin through the production of H2O2 mediated by diamine oxidases in soybean hypocotyls.

  Journal of plant physiology 20051201

• Ionizing radiation induces DNA double-strand breaks in bystander primary human fibroblasts.

  Oncogene 20051110

• Nitric oxide mediated oxidative stress injury in rat skeletal muscle subjected to ischemia/reperfusion as evaluated by chemiluminescence.

  Nitric oxide : biology and chemistry 20051101

• Vascular endothelial growth factor receptor-2 and low affinity VEGF binding sites on human glomerular endothelial cells: Biological effects and advanced glycosilation end products modulation.

  Microvascular research 20051101

• Induction of vascular endothelial growth factor messenger ribonucleic acid expression in stored micrografts by aminoguanidine.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20051101

• [Aminoguanidine decreases the brain damage in rats neonatally exposed to hypoxic-ischemic influences].

  Georgian medical news 20051001

• Induction of angiogenesis by platelet-activating factor in the rat striatum.

  Neuroreport 20050928

• Experiments with nitric oxide synthase inhibitors in spinal nerve ligated rats provide no evidence of a role for nitric oxide in neuropathic mechanical allodynia.

  Neuroscience letters 20050916

• Nitric oxide in blastocyst implantation in the rhesus monkey.

  Reproduction (Cambridge, England) 20050901

• Effect of aminoguanidine on ischemia-reperfusion induced myocardial injury in rats.

  Molecular and cellular biochemistry 20050901

• Diameter of the cochlear nerve in endolymphatic hydrops: implications for the etiology of hearing loss in Ménière's disease.

  The Laryngoscope 20050901

• The importance of the phagocytes' innate response in resolution of the infection induced by a low virulent Candida albicans mutant.

  Scandinavian journal of immunology 20050901

• Nitric oxide mediates the interleukin-1beta- and nicotine-induced hypothalamic-pituitary-adrenocortical response during social stress.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20050901

• Concentrations of nitric oxide in rat brain tissues after diffuse brain injury and neuroprotection by the selective inducible nitric oxide synthase inhibitor aminoguanidine.

  Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20050901

• Acute inhibition of inducible nitric oxide synthase but not its absence suppresses asthma-like responses.

  European journal of pharmacology 20050822

• Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation.

  American journal of physiology. Renal physiology 20050801

• Activation of phosphoinositide 3-kinase in response to inflammation and nitric oxide leads to the up-regulation of cyclooxygenase-2 expression and subsequent cell proliferation in mesangial cells.

  Cellular signalling 20050801

• Endotoxin releases a substance from the aorta that dilates an isolated arteriole by up-regulating INOS.

  The Journal of surgical research 20050801

• Effect of buformin and metformin on formation of advanced glycation end products by methylglyoxal.

  Clinica chimica acta; international journal of clinical chemistry 20050801

• Expression of inducible nitric oxide synthase in transplanted rat liver and its inhibitory effect.

  Hepatobiliary & pancreatic diseases international : HBPD INT 20050801

• Neuroprotective effects of indomethacin and aminoguanidine in the newborn rats with hypoxic-ischemic cerebral injury.

  Neurochemical research 20050801

• Lentivirus infection causes neuroinflammation and neuronal injury in dorsal root ganglia: pathogenic effects of STAT-1 and inducible nitric oxide synthase.

  Journal of immunology (Baltimore, Md. : 1950) 20050715

• Anti-cancer effect of iNOS inhibitor and its correlation with angiogenesis in gastric cancer.

  World journal of gastroenterology 20050707

• Ilex paraguariensis extracts inhibit AGE formation more efficiently than green tea.

  Fitoterapia 20050701

• Oxidative stress induces vascular heme oxygenase-1 expression in ovariectomized rats.

  Free radical biology & medicine 20050701

• Reactive carbonyls and polyunsaturated fatty acids produce a hydroxyl radical-like species: a potential pathway for oxidative damage of retinal proteins in diabetes.

  The Journal of biological chemistry 20050617

• Effects of chronic inhibition of inducible nitric oxide synthase in hyperthyroid rats.

  American journal of physiology. Endocrinology and metabolism 20050601

• Chronic administration of aminoguanidine reduces vascular nitric oxide production and attenuates liver damage in bile duct-ligated rats.

  Liver international : official journal of the International Association for the Study of the Liver 20050601

• Nitric oxide synthase inhibition prevents alveolar bone resorption in experimental periodontitis in rats.

  Journal of periodontology 20050601

• Psychosocial stress affects the involvement of prostaglandins and nitric oxide in the lipopolysaccharide-induced hypothalamic-pituitary-adrenal response.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20050601

• [Progress on the drug therapy for diabetic microangiopathies: AGE inhibitors].

  Nihon rinsho. Japanese journal of clinical medicine 20050601

• [Potential pharmacological treatments for diabetic retinopathy].

  Nihon rinsho. Japanese journal of clinical medicine 20050601

• The role of AGEs and AGE inhibitors in diabetic cardiovascular disease.

  Current drug targets 20050601

• Assessment of protein function following cross-linking by alpha-dicarbonyls.

  Annals of the New York Academy of Sciences 20050601

• From molecular footprints of disease to new therapeutic interventions in diabetic nephropathy.

  Annals of the New York Academy of Sciences 20050601

• Can advanced glycation end product inhibitors modulate more than one pathway to enhance renoprotection in diabetes?

  Annals of the New York Academy of Sciences 20050601

• Inhibitors of advanced glycation end product formation and neurovascular dysfunction in experimental diabetes.

  Annals of the New York Academy of Sciences 20050601

• Post-Amadori AGE inhibition as a therapeutic target for diabetic complications: a rational approach to second-generation Amadorin design.

  Annals of the New York Academy of Sciences 20050601

• alpha2-Adrenoceptor subsensitivity in mesenteric vascular bed of cholestatic rats: the role of nitric oxide and endogenous opioids.

  European journal of pharmacology 20050509

• Peroxynitrite may be involved in bladder damage caused by cyclophosphamide in rats.

  The Journal of urology 20050501

• Nitric oxide modulates peristaltic muscle activity associated with fluid circulation in the sea pansy Renilla koellikeri.

  The Journal of experimental biology 20050501

• Obligatory role of inducible nitric oxide synthase in ischemic preconditioning.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20050401

• Evaluation of inducible nitric oxide synthase in glaucomatous optic neuropathy and pressure-induced optic nerve damage.

  Investigative ophthalmology & visual science 20050401

• Inducible nitric oxide synthase-derived nitric oxide regulates germinal vesicle breakdown and first polar body emission in the mouse oocyte.

  Reproduction (Cambridge, England) 20050401

• Modulating the effects of diabetes on osseointegration with aminoguanidine and doxycycline.

  Journal of periodontology 20050401

• [Aminoguanidin improves learning process in neonatal rats exposed to hypoxia-ischemia].

  Georgian medical news 20050401

• Inducible nitric oxide synthase contributes to intermittent hypoxia against ischemia/reperfusion injury.

  Acta pharmacologica Sinica 20050301

• The effects of selective nitric oxide synthase blocker on survival, mesenteric blood flow and multiple organ failure induced by zymosan.

  The Journal of surgical research 20050301

• Inhibitors of iNOS protects PC12 cells against the apoptosis induced by oxygen and glucose deprivation.

  Neuroscience letters 20050225

• Inducible nitric oxide synthase activity and expression in liver and hepatocytes of diabetic rats.

  Pharmacology 20050201

• Nitric oxide synthase inhibitors and nitric oxide donors modulate the biosynthesis of thaxtomin A, a nitrated phytotoxin produced by Streptomyces spp.

  Nitric oxide : biology and chemistry 20050201

• Sensitization of mesenteric afferents to chemical and mechanical stimuli following systemic bacterial lipopolysaccharide.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20050201

• The role of selective nitric oxide synthase inhibitor on nitric oxide and PGE2 levels in refractory hemorrhagic-shocked rats.

  The Journal of surgical research 20050201

• Nitric oxide synthases inhibition results in renal failure improvement in cirrhotic rats.

  Liver international : official journal of the International Association for the Study of the Liver 20050201

• Identification of aldehyde oxidase as the neonicotinoid nitroreductase.

  Chemical research in toxicology 20050201

• [Decrease of nitric oxide (NO)-cGMP-dependent vasodilatation in the vessels of lesser circulation in endothelial dysfunction].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20050201

• Effects of nitric oxide synthase inhibitors on porcine oocyte meiotic maturation.

  Zygote (Cambridge, England) 20050201

• Hyperbaric oxygen protects against lipopolysaccharide-stimulated oxidative stress and mortality in rats.

  European journal of pharmacology 20050131

• Beneficial effects of aminoguanidine on the cardiovascular system of diabetic rats.

  Diabetes/metabolism research and reviews 20050101

• Reversal by aminoguanidine of the age-related increase in glycoxidation and lipoxidation in the cardiovascular system of Fischer 344 rats.

  Biochemical pharmacology 20050101

• The carbonyl scavengers aminoguanidine and tenilsetam protect against the neurotoxic effects of methylglyoxal.

  Neurotoxicity research 20050101

• In vivo PAF-induced airway eosinophil accumulation reduces bronchial responsiveness to inhaled histamine.

  Prostaglandins & other lipid mediators 20050101

• [Modification of cellular radiosensitivity by NO-synthase inhibitors].

  Radiatsionnaia biologiia, radioecologiia 20050101

• [Targeted AGEes and AGEs cross-link in drug discovery: preventing and reversing arterial sclerosis in aging and diabetes].

  Yao xue xue bao = Acta pharmaceutica Sinica 20050101

• [Effect of chronic administration of aminoguanidine on vascular reactivity of the greater circulation in rats with monocrotaline-induced pulmonary hypertension].

  Izvestiia Akademii nauk. Seriia biologicheskaia 20050101

• Anti-inflammatory effects of specific cyclooxygenase 2,5-lipoxygenase, and inducible nitric oxide synthase inhibitors on experimental autoimmune anterior uveitis (EAAU).

  Ocular immunology and inflammation 20050101

• Inducible nitric oxide synthase subserves cholinergic vasodilation in retina.

  Visual neuroscience 20050101

• Aminoguanidine prevents ototoxicity induced by cisplatin in rats.

  Annals of clinical and laboratory science 20050101

• Potential role of inducible nitric oxide synthase in the sleep-wake states occurrence in old rats.

  Neuroscience 20050101

• Application of high-order derivative spectrophotometry for studying the interaction of calcium ions with various anticoccidial aminoguanidine derivatives.

  Doklady. Biochemistry and biophysics 20050101

• The role of nitric oxide in resistance to P. aeruginosa ocular infection.

  Ocular immunology and inflammation 20050101

• Effect of aminoguanidine and albendazole on inducible nitric oxide synthase (iNOS) activity in T. spiralis-infected mice muscles.

  Folia histochemica et cytobiologica 20050101

• Activity of peroxisomal enzymes, and levels of polyamines in LPA-transgenic mice on two different diets.

  Lipids in health and disease 20050101

• Development of intestinal, but not gastric damage caused by a low dose of indomethacin in the presence of rofecoxib.

  Inflammopharmacology 20050101

• Advanced glycation end products and diabetic nephropathy.

  American journal of therapeutics 20050101

• Collagen ultrastructure and TGF-beta1 expression preserved with aminoguanidine during wound healing in diabetic rats.

  Endocrine research 20050101

• In vivo inhibition of inducible nitric oxide and evaluation of the brain tissue damage induced by Toxocara canis larvae in experimentally infected mice.

  The Chinese journal of physiology 20041231

• Preservation of neurological functions by nitric oxide synthase inhibitors in conscious rats following delayed hemorrhagic shock.

  Life sciences 20041224

• Role of inducible nitric oxide synthase in N-methyl-d-aspartic acid-induced strio-nigral degeneration.

  Brain research 20041210

• [Aminoguanidine prevents peroxynitrite production and cardiac hypertrophy in streptozotocin-induced diabetic rats].

  Orvosi hetilap 20041205

• Time-level relationship for nitric oxide and the protective effects of aminoguanidine in experimental spinal cord injury.

  Acta neurochirurgica 20041201

• Septic diaphragmatic dysfunction is prevented by Mn(III)porphyrin therapy and inducible nitric oxide synthase inhibition.

  Intensive care medicine 20041201

• Interaction between inducible nitric oxide synthase and poly(ADP-ribose) polymerase in focal ischemic brain injury.

  Stroke 20041201

• Clinical studies of advanced glycation end product inhibitors and diabetic kidney disease.

  Current diabetes reports 20041201

• Effects of iNOS inhibitor on IFN-gamma production and apoptosis of splenocytes in genetically different strains of mice infected with Toxoplasma gondii.

  The Korean journal of parasitology 20041201

• The expression of heme oxygenase-1 and inducible nitric oxide synthase in aorta during the development of hypertension in spontaneously hypertensive rats.

  American journal of hypertension 20041201

• Dual role of endogenous nitric oxide in development of dextran sodium sulfate-induced colitis in rats.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20041201

• Effects of nitric oxide synthase inhibition on intestinal damage in rats with experimental necrotizing enterocolitis.

  European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie 20041201

• The role of nitric oxide on contractile impairment during endotoxemia in rat diaphragm muscle.

  European journal of pharmacology 20041128

• Hepatic flavin-containing monooxygenase activity attenuated by cGMP-independent nitric oxide-mediated mRNA destabilization.

  Biochemical and biophysical research communications 20041105

• The role of advanced glycation in reduced organic cation transport associated with experimental diabetes.

  The Journal of pharmacology and experimental therapeutics 20041101

• Attenuation of extracellular matrix accumulation in diabetic nephropathy by the advanced glycation end product cross-link breaker ALT-711 via a protein kinase C-alpha-dependent pathway.

  Diabetes 20041101

• Aminoguanidine prevents fructose-induced arterial stiffening in Wistar rats: aortic impedance analysis.

  Experimental biology and medicine (Maywood, N.J.) 20041101

• Spermine acts as a negative regulator of macrophage differentiation in human myeloid leukemia cells.

  Cancer research 20041015

• Stress-restress evokes sustained iNOS activity and altered GABA levels and NMDA receptors in rat hippocampus.

  Psychopharmacology 20041001

• Interaction between NO and COX pathways in retinal cells exposed to elevated glucose and retina of diabetic rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20041001

• Macrophages enhance the radiosensitizing activity of lipid A: a novel role for immune cells in tumor cell radioresponse.

  International journal of radiation oncology, biology, physics 20041001

• Tumour-derived and host-derived nitric oxide differentially regulate breast carcinoma metastasis to the lungs.

  Carcinogenesis 20040901

• Advanced glycation end products induce secretion of chemokines and apoptosis in human first trimester trophoblasts.

  Human reproduction (Oxford, England) 20040901

• Isoflurane preconditioning induces neuroprotection that is inducible nitric oxide synthase-dependent in neonatal rats.

  Anesthesiology 20040901

• A possible role for nitric oxide in osteoclastogenesis associated with cholesteatoma.

  Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20040901

• Role of prostaglandins and nitric oxide in the lipopolysaccharide-induced ACTH and corticosterone response.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20040901

• Macrophages in the development of protective immunity against experimental Brugia malayi infection.

  Parasitology 20040901

• Endothelin-1-mediated coronary vasoconstriction deteriorates myocardial depression in hearts isolated from lipopolysaccharide-treated rats: interaction with nitric oxide.

  Clinical and experimental pharmacology & physiology 20040901

• Effects of aminoguanidine and antioxidant erdosteine on bleomycin-induced lung fibrosis in rats.

  Nitric oxide : biology and chemistry 20040901

• [Septic shock and NO].

  Nihon rinsho. Japanese journal of clinical medicine 20040901

• Effect of carbonyl compounds on red blood cells deformability.

  Biochemical and biophysical research communications 20040827

• Pharmacological prevention of cardiovascular aging--targeting the Maillard reaction.

  British journal of pharmacology 20040801

• Aminoguanidine prevents age-related deterioration in left ventricular-arterial coupling in Fisher 344 rats.

  British journal of pharmacology 20040801

• Endogenous nitric oxide protects against T cell-dependent lethality during graft-versus-host disease and idiopathic pneumonia syndrome.

  Journal of immunology (Baltimore, Md. : 1950) 20040801

• Davis BJ, Forbes JM, Thomas MC et al. (2004) Superior renoprotective effects of combination therapy with ACE and AGE inhibition in the diabetic spontaneously hypertensive rat. Diabetologia 47:89-97.

  Diabetologia 20040801

• Protective effect of aminoguanidine against nephrotoxicity induced by amikacin in rats.

  Urological research 20040801

• The protective effect of aminoguanidine on erectile function in diabetic rats is not related to the timing of treatment.

  BJU international 20040801

• [Effects of nitric oxide synthase inhibitors on cerebral mitochondrial structure and function in fetal rats with intrauterine distress].

  Zhonghua fu chan ke za zhi 20040801

• Iron down-regulates macrophage anti-tumour activity by blocking nitric oxide production.

  Clinical and experimental immunology 20040701

• Advanced glycation end product interventions reduce diabetes-accelerated atherosclerosis.

  Diabetes 20040701

• Modification of endothelial cell functions by Hantaan virus infection: prolonged hyper-permeability induced by TNF-alpha of hantaan virus-infected endothelial cell monolayers.

  Archives of virology 20040701

• Effects of aminoguanidine and L-arginine methyl ester resuscitation following induction of fluid-percussion injury and severe controlled hemorrhagic shock in the rat brain.

  Journal of neurosurgery 20040701

• [Effect of chronic administration of aminoguanidine on the reactivity of pulmonary vessels in rats with monocrotaline-induced pulmonary hypertension].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20040701

• Lung microvascular permeability and neutrophil recruitment are differently regulated by nitric oxide in a rat model of intestinal ischemia-reperfusion.

  European journal of pharmacology 20040628

• Modulation of iNOS activity in age-related cardiac dysfunction.

  Life sciences 20040625

• Poorer NF-kappa B signaling by microfilariae in macrophages from BALB/c mice affects their ability to produce cytotoxic levels of nitric oxide to kill microfilariae.

  FEBS letters 20040604

• [Aminoguanidine and impaired wound healing in diabetes].

  Zhonghua yi xue za zhi 20040602

• Impaired NO signaling in small pulmonary arteries of chronically hypoxic newborn piglets.

  American journal of physiology. Lung cellular and molecular physiology 20040601

• Early inhibition of nitric oxide production increases HSV-1 intranasal infection.

  Journal of medical virology 20040601

• COX-2 and iNOS in opioid-induced delayed cardioprotection in the intact rat.

  Life sciences 20040528

• Interaction of inducible nitric oxide synthase and cyclooxygenase-2 inhibitors in formalin-induced nociception in mice.

  European journal of pharmacology 20040525

• 4-Hydroxy tempol-induced impairment of mitochondrial function and augmentation of glucose transport in vascular endothelial and smooth muscle cells.

  Biochemical pharmacology 20040515

• Blockade of quinolinic acid-induced neurotoxicity by pyruvate is associated with inhibition of glial activation in a model of Huntington's disease.

  Experimental neurology 20040501

• Involvement of nitric oxide (NO) and TNF-alpha in the oxidative stress associated with anemia in experimental Trypanosoma cruzi infection.

  FEMS immunology and medical microbiology 20040501

• Influence of selective nitric oxide synthetase inhibitor for treatment of refractory haemorrhagic shock.

  Resuscitation 20040501

• Aminoguanidine protects against intracranial hypertension and cerebral ischemic injury in experimental heatstroke.

  Journal of pharmacological sciences 20040501

• Unexpected elevation of pentosidine formation in collagen incubated with glucose by low concentrations of the AGE-inhibitor aminoguanidine.

  Diabetologia 20040501

• [Carbonyl stress inhibitor towards new therapeutic interventions in diabetic nephropathy].

  Nihon rinsho. Japanese journal of clinical medicine 20040501

• [Changes of iNOS genes expression in liver following ischemia and reperfusion of limbs and their significance in rats].

  Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20040501

• Changes in plasma membrane Ca2+ -ATPase expression and ATP content in lenses of hereditary cataract UPL rats.

  Toxicology 20040415

• Nitric oxide modulation of the immune response against cholera toxin-adjuvated ovalbumin administered by the intranasal route.

  Immunology letters 20040415

• Effect of aminoguanidine in ligature-induced periodontitis in rats.

  Journal of dental research 20040401

• Influence of endogenous nitric oxide on sympathetic vasoconstriction in normoxia, acute and chronic systemic hypoxia in the rat.

  The Journal of physiology 20040316

• Role of nitric oxide in myotoxic activity induced by crotoxin in vivo.

  Toxicon : official journal of the International Society on Toxinology 20040315

• Pyridoxal-aminoguanidine adduct is more effective than aminoguanidine in preventing neuropathy and cataract in diabetic rats.

  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20040301

• Cholecystokinin-induced gastroprotection: a review of current protective mechanisms.

  Digestive diseases and sciences 20040301

• [Effects of aminoguanidine in different dosages on renal function in endotoxin induced rabbits shock model].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20040301

• Reactive oxygen and nitrogen intermediates contribute to Haemophilus somnus lipooligosaccharide-mediated apoptosis of bovine endothelial cells.

  Veterinary immunology and immunopathology 20040201

• Cyclosporine treatment preserves coronary resistance artery function in rat cardiac allografts.

  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20040201

• Neuroprotective role of aminoguanidine in behavioral changes after blast injury.

  The Journal of trauma 20040201

• [Effects of aminoguanidine on the expression of NOS in facial nerve and surrounding tissues of traumatic facial paralysis rats].

  Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20040201

• NO plays a role in LPS-induced decreases in circulating IGF-I and IGFBP-3 and their gene expression in the liver.

  American journal of physiology. Endocrinology and metabolism 20040101

• Superior renoprotective effects of combination therapy with ACE and AGE inhibition in the diabetic spontaneously hypertensive rat.

  Diabetologia 20040101

• Reactive nitrogen species scavenging, rather than nitric oxide inhibition, protects from articular cartilage damage in rat zymosan-induced arthritis.

  British journal of pharmacology 20040101

• Randomized trial of an inhibitor of formation of advanced glycation end products in diabetic nephropathy.

  American journal of nephrology 20040101

• Increased MMP-9 expression and activity by aortic smooth muscle cells after nitric oxide synthase inhibition is associated with increased nuclear factor-kappaB and activator protein-1 activity.

  The Journal of surgical research 20040101

• Role of polymorphonuclear leukocytes, nitric oxide synthase, and cyclooxygenase in vascular permeability changes induced by C5a agonist peptides.

  Molecular cancer therapeutics 20040101

• A new therapeutic approach for the treatment of sepsis.

  Medical hypotheses 20040101

• Advanced glycation end-products and the progress of diabetic vascular complications.

  Physiological research 20040101

• Effects of aminoguanidine and cyclooxygenase inhibitors on nitric oxide and prostaglandin production, and nitric oxide synthase and cyclooxygenase expression induced by lipopolysaccharide in the estrogenized rat uterus.

  Neuroimmunomodulation 20040101

• Vasoactive systems in L-NAME hypertension: the role of inducible nitric oxide synthase.

  Journal of hypertension 20040101

• Application of combined magnetic resonance imaging and histopathologic and functional studies for evaluation of aminoguanidine following traumatic brain injury in rats.

  Methods in enzymology 20040101

• Nitric oxide and oxidative stress in brain and heart of normal rats treated with doxorubicin: role of aminoguanidine.

  Journal of biochemical and molecular toxicology 20040101

• Amelioration of the beta-cell dysfunction in diabetic APA hamsters by antioxidants and AGE inhibitor treatments.

  Diabetes/metabolism research and reviews 20040101

• [Effect of tetromethylpyrazine and aminoguanidine on expression of vascular endothelial growth factor in kidney of diabetic rats].

  Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20040101

• The effect of nitric oxide synthases inhibitors on inflammatory bowel disease in a rat model.

  In vivo (Athens, Greece) 20040101

• The protective effect of aminoguanidine on cerebral ischemic damage in the rat brain.

  Physiological research 20040101

• p21ras activation following hypoxia-ischemia in the newborn rat brain is dependent on nitric oxide synthase activity but p21ras does not contribute to neurologic injury.

  Brain research. Developmental brain research 20031219

• Aminoguanidine downregulates expression of cytokine-induced Fas and inducible nitric oxide synthase but not cytokine-enhanced surface antigens of rat islet cells.

  Biochemical pharmacology 20031215

• The inhibition of inducible nitric oxide synthase reverts arthritic-induced decrease in pituitary growth hormone mRNA but not in liver insulin-like growth factor I mRNA expression.

  Journal of neuroendocrinology 20031201

• Antioxidant activity of a Schiff base of pyridoxal and aminoguanidine.

  Free radical biology & medicine 20031201

• Aminoguanidine reduces cisplatin ototoxicity.

  Hearing research 20031201

• Carnosine inhibits (E)-4-hydroxy-2-nonenal-induced protein cross-linking: structural characterization of carnosine-HNE adducts.

  Chemical research in toxicology 20031201

• A detective story for biomedical footprints towards new therapeutic interventions in diabetic nephropathy.

  Internal medicine (Tokyo, Japan) 20031201

• The effects of chronic administration of inhibitors of flavin and quinone amine oxidases on imidazoline I(1) receptor density in rat whole brain.

  Annals of the New York Academy of Sciences 20031201

• Effect of inducible nitric oxide synthase inhibition by aminoguanidine on insulin-like growth factor binding protein-3 in adjuvant-induced arthritic rats.

  European journal of pharmacology 20031128

• A quantitative model of the generation of N(epsilon)-(carboxymethyl)lysine in the Maillard reaction between collagen and glucose.

  The Biochemical journal 20031115

• Role of lipid peroxidation as a mechanism of liver injury after acetaminophen overdose in mice.

  Toxicological sciences : an official journal of the Society of Toxicology 20031101

• Lipid a radiosensitizes hypoxic EMT-6 tumor cells: role of the NF-kappaB signaling pathway.

  International journal of radiation oncology, biology, physics 20031101

• Nitric oxide synthase inhibitors modulate lipopolysaccharide-induced hepatocyte injury: dissociation between in vivo and in vitro effects.

  International immunopharmacology 20031101

• Use of aminoguanidine (Pimagedine) to prevent the formation of advanced glycation endproducts.

  Archives of biochemistry and biophysics 20031101

• Evolving concepts in advanced glycation, diabetic nephropathy, and diabetic vascular disease.

  Archives of biochemistry and biophysics 20031101

• Therapeutic potential of breakers of advanced glycation end product-protein crosslinks.

  Archives of biochemistry and biophysics 20031101

• NOS inhibitors exhibit antinociceptive properties in the rat formalin test.

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 20031101

• Secondary growth of a cortical necrosis: effect of NOS inhibition by aminoguanidine post insult.

  Acta neurochirurgica 20031101

• Comparison of iNOS inhibition by antisense and pharmacological inhibitors after spinal cord injury.

  Journal of neuropathology and experimental neurology 20031101

• Neutrophil migration in inflammation: nitric oxide inhibits rolling, adhesion and induces apoptosis.

  Nitric oxide : biology and chemistry 20031101

• [Influence of electro-acupuncture of Neiguan on plasmic concentrations of NO and TNFalpha in endotoxin shock rats].

  Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20031101

• Concomitant production of nitric oxide and superoxide in human macrophages.

  Biochemical and biophysical research communications 20031017

• Modulation by alpha-difluoromethyl-ornithine and aminoguanidine of pain threshold, morphine analgesia and tolerance.

  European journal of pharmacology 20031008

• Molecular and pharmacological approaches to inhibiting nitric oxide after burn trauma.

  American journal of physiology. Heart and circulatory physiology 20031001

• Role of the nitric-oxide synthase isoforms during morphine-induced hyperthermia in rats.

  The Journal of pharmacology and experimental therapeutics 20031001

• The protective effect of aminoguanidine on erectile function in streptozotocin diabetic rats.

  The Journal of urology 20031001

• Inhibition of advanced glycation end-products protects against retinal capillary basement membrane expansion during long-term diabetes.

  The Journal of pathology 20031001

• Effects of endothelin and nitric oxide on organ injury, mesenteric ischemia, and survival in experimental models of septic shock.

  Acta pharmacologica Sinica 20031001

• Paradoxical protective effect of aminoguanidine toward low-density lipoprotein oxidation: inhibition of apolipoprotein B fragmentation without preventing its carbonylation. Mechanism of action of aminoguanidine.

  Biochemistry 20030930

• Concentrations of nitric oxide in equine preovulatory follicles before and after administration of human chorionic gonadotropin.

  Theriogenology 20030915

• The selective role of nitric oxide in opioid-mediated footshock stress antinociception in mice.

  Physiology & behavior 20030901

• Role of nitric oxide in the renal protective effects of ischemic preconditioning.

  Journal of cardiovascular pharmacology 20030901

• Aminoguanidine prevents age-related aortic stiffening in Fisher 344 rats: aortic impedance analysis.

  British journal of pharmacology 20030901

• Potentiation of diclofenac-induced anti-inflammatory response by aminoguanidine in carrageenan-induced acute inflammation in rats: the role of nitric oxide.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030901

• EPR investigation of in vivo inhibitory effect of guanidine compounds on nitric oxide production in rat tissues.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20030901

• FK 506 and aminoguanidine suppress iNOS induction in orthotopic corneal allografts and prolong graft survival in mice.

  Nitric oxide : biology and chemistry 20030901

• Modulation of D-penicillamine-induced autoimmunity in the Brown Norway rat using pharmacological agents that interfere with arachidonic acid metabolism or synthesis of inducible nitric oxide synthase.

  Toxicology 20030828

• The role of inducible nitric oxide synthase inhibitor on the arteriolar hyporesponsiveness in hemorrhagic-shocked rats.

  Life sciences 20030822

• Design of weakly basic thrombin inhibitors incorporating novel P1 binding functions: molecular and X-ray crystallographic studies.

  Biochemistry 20030805

• Inhibition of neuronal nitric oxide synthase by 7-nitroindazole attenuates acute lung injury in an ovine model.

  American journal of physiology. Regulatory, integrative and comparative physiology 20030801

• Lipopolysaccharide and inflammatory cytokines cause an inducible nitric oxide synthase-dependent bladder smooth muscle fibrotic response.

  The Journal of urology 20030801

• Triosephosphates are toxic to superoxide dismutase-deficient Escherichia coli.

  Biochimica et biophysica acta 20030723

• Downregulation of nitric oxide synthase in nephrotic syndrome: role of proteinuria.

  Biochimica et biophysica acta 20030714

• Effect of nitric oxide on lung surfactant secretion.

  Experimental lung research 20030701

• Role of endogenous peroxynitrite in pulmonary injury and fibrosis induced by bleomycin A5 in rats.

  Acta pharmacologica Sinica 20030701

• Effect of aminoguanidine on the recovery of rat hindlimb motor function after spinal cord injury.

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20030701

• Behavioral effects of NMDA receptor agonists and antagonists in combination with nitric oxide-related compounds.

  European journal of pharmacology 20030620

• Induction of phase 2 enzymes by serum oxidized polyamines through activation of Nrf2: effect of the polyamine metabolite acrolein.

  Biochemical and biophysical research communications 20030606

• Deficiency of nitric oxide synthase 2 results in increased neointima formation in a mouse model of vascular injury.

  Journal of cardiovascular pharmacology 20030601

• Nitric oxide synthase activity in Fasciola hepatica: a radiometric study.

  Parasitology 20030601

• Gypenosides derived from Gynostemma pentaphyllum suppress NO synthesis in murine macrophages by inhibiting iNOS enzymatic activity and attenuating NF-kappaB-mediated iNOS protein expression.

  Nitric oxide : biology and chemistry 20030601

• Effect of ornithine on the ileal histology, nitric oxide production and lipid peroxidation in LPS-induced endotoxemia.

  Acta medica Okayama 20030601

• Copper induces type II nitric oxide synthase in vivo.

  Free radical biology & medicine 20030515

• The effects of early and late administration of inhibitors of inducible nitric oxide synthase in a thioacetamide-induced model of acute hepatic failure in the rat.

  Journal of hepatology 20030501

• Competition and binding of arginine, imidazole, and aminoguanidine to endothelial nitric oxide synthase: aminoguanidine is a poor model for substrate, intermediate, and arginine analog inhibitor binding.

  Nitric oxide : biology and chemistry 20030501

• Role of inducible nitric oxide synthase in pig liver transplantation.

  The Journal of surgical research 20030501

• Glycated collagen cross-linking alters cardiac mechanics in volume-overload hypertrophy.

  American journal of physiology. Heart and circulatory physiology 20030401

• Supplementation and inhibition of nitric oxide synthesis influences bacterial transit time during bacterial translocation in rats.

  Shock (Augusta, Ga.) 20030401

• Intervention with nitric oxide synthase inhibitors for traumatic shock in rats.

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20030401

• Segmental analysis of molecular surface electrostatic potentials: application to enzyme inhibition.

  Journal of molecular modeling 20030401

• Two flavone C-glycosides from the style of Zea mays with glycation inhibitory activity.

  Journal of natural products 20030401

• A comparison of hepatoprotective activities of aminoguanidine and N-acetylcysteine in rat against the toxic damage induced by azathioprine.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20030401

• Early and intermediate Amadori glycosylation adducts, oxidative stress, and endothelial dysfunction in the streptozotocin-induced diabetic rats vasculature.

  Diabetologia 20030401

• Effect of protease-activated receptors on guinea-pig ileum contraction in vitro.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030401

• Aminosalicylic acid reduces the antiproliferative effect of hyperglycaemia, advanced glycation endproducts and glycated basic fibroblast growth factor in cultured bovine aortic endothelial cells: comparison with aminoguanidine.

  Molecular and cellular biochemistry 20030401

• [Effect of dexamethasone, aminoguanidin, amrinone on oxygen utilization in endotoxin shock rabbits].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20030401

• New insights into protein crosslinking via the Maillard reaction: structural requirements, the effect on enzyme function, and predicted efficacy of crosslinking inhibitors as anti-ageing therapeutics.

  Bioorganic & medicinal chemistry 20030320

• Nitric oxide induces macrophage apoptosis following traumatic brain injury in rats.

  Neuroscience letters 20030320

• Cholecystokinin secretagogue-induced gastroprotection: role of nitric oxide and blood flow.

  American journal of physiology. Gastrointestinal and liver physiology 20030301

• Graded sensitiveness of the various retinal neuron populations on the glyoxal-mediated formation of advanced glycation end products and ways of protection.

  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20030301

• The effects of FK506 on the development and expression of morphine tolerance and dependence in mice.

  Behavioural pharmacology 20030301

• ACE inhibition salvages the visual loss caused by diabetes.

  Diabetologia 20030301

• Mechanisms of salt-sensitive hypertension: role of renal medullary inducible nitric oxide synthase.

  American journal of physiology. Regulatory, integrative and comparative physiology 20030201

• Delay of cataract development in hereditary cataract UPL rats by disulfiram and aminoguanidine.

  Experimental eye research 20030201

• Neuroprotection by aminoguanidine after lateral fluid-percussive brain injury in rats: a combined magnetic resonance imaging, histopathologic and functional study.

  Neuropharmacology 20030201

• The role of nitric oxide after a short period of liver ischemia-reperfusion.

  The Journal of surgical research 20030201

• Involvement of peroxynitrite in LPS-induced apoptosis of trophoblasts.

  The journal of obstetrics and gynaecology research 20030201

• Loss of lipopolysaccharide-induced nitric oxide production and inducible nitric oxide synthase expression in scrapie-infected N2a cells.

  Journal of neuroscience research 20030115

• Neuroinflammatory role of prostaglandins during experimental meningitis: evidence suggestive of an in vivo relationship between nitric oxide and prostaglandins.

  The Journal of pharmacology and experimental therapeutics 20030101

• Cross-linking of glycated collagen in the pathogenesis of arterial and myocardial stiffening of aging and diabetes.

  Journal of hypertension 20030101

• Dysfunctional microvascular conducted response in irradiated normal tissue.

  Advances in experimental medicine and biology 20030101

• Limitations of ischemic tolerance in oxidative skeletal muscle: perfusion vs tissue protection.

  The Journal of surgical research 20030101

• The fundamental role of increased production of nitric oxide in lipopolysaccharide-induced embryonic resorption in mice.

  Reproduction (Cambridge, England) 20030101

• Hemodynamic and hepatic microcirculational changes in endotoxemic rats treated with different NOS inhibitors.

  Hepato-gastroenterology 20030101

• Nitric oxide-dependent regulation of pro-inflammatory cytokines in group B streptococcal inflammation of rat lung.

  Annals of clinical and laboratory science 20030101

• [Advanced glycosylation end products and chronic complications of diabetes mellitus].

  Gaceta medica de Mexico 20030101

• Cytotoxicity test and cytogenetic analysis of effects of aminoguanidine in vitro.

  Methods and findings in experimental and clinical pharmacology 20030101

• The effect of selected membrane active substances on erythrocyte deformability.

  Bratislavske lekarske listy 20030101

• Inhibition of matrix metalloproteinase-1 and -2 expression using nitric oxide synthase inhibitors in UV-irradiated human dermal fibroblasts.

  Journal of cosmetic science 20030101

• Inducible nitric oxide synthase inhibitors prolonged the survival of skin xenografts through selective down-regulation of pro-inflammatory cytokine and CC-chemokine expressions.

  Transplant immunology 20030101

• Advanced glycation in uraemic toxicity.

  EDTNA/ERCA journal (English ed.) 20030101

• Nitric oxide synthase in Entamoeba histolytica: its effect on rat aortic rings.

  Experimental parasitology 20030101

• Steroid hormones augment nitric oxide synthase activity and expression in rat uterus.

  Reproduction, fertility, and development 20030101

• Clinical potential of advanced glycation end-product inhibitors in diabetes mellitus.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20030101

• Aldehyde-sequestering drugs: tools for studying protein damage by lipid peroxidation products.

  Toxicology 20021227

• The botanical extracts of Achyrocline satureoides and Ilex paraguariensis prevent methylglyoxal-induced inhibition of plasminogen and antithrombin III.

  Life sciences 20021206

• Expression of inducible nitric oxide synthase in human umbilical vein endothelial cells during primary culture.

  Nitric oxide : biology and chemistry 20021201

• Renal connective tissue growth factor induction in experimental diabetes is prevented by aminoguanidine.

  Endocrinology 20021201

• Inhibition of nitric oxide enhances ovine lentivirus replication in monocyte-derived macrophages.

  Veterinary immunology and immunopathology 20021201

• Effect of NO synthase inhibition on cardiovascular and pulmonary dysfunction in a porcine short-term model of endotoxic shock.

  Prostaglandins, leukotrienes, and essential fatty acids 20021201

• Aminoguanidine inhibits mitogen-activated protein kinase and improves cardiac performance and cardiovascular remodeling in failing hearts of salt-sensitive hypertensive rats.

  Journal of hypertension 20021201

• Putrescine activates oxidative stress dependent apoptotic death in ornithine decarboxylase overproducing mouse myeloma cells.

  Experimental cell research 20021115

• Nitric oxide released from iNOS in polymorphonuclear leukocytes makes them deformable in an autocrine manner.

  Nitric oxide : biology and chemistry 20021101

• Ouabain-induced hypertension is accompanied by increases in endothelial vasodilator factors.

  American journal of physiology. Heart and circulatory physiology 20021101

• Vaccinia virus induces apoptosis of infected macrophages.

  The Journal of general virology 20021101

• Nitric oxide inhibits oocyte meiotic maturation.

  Biology of reproduction 20021101

• Reduction of the accumulation of advanced glycation end products by ACE inhibition in experimental diabetic nephropathy.

  Diabetes 20021101

• ALT-946 and aminoguanidine, inhibitors of advanced glycation, improve severe nephropathy in the diabetic transgenic (mREN-2)27 rat.

  Diabetes 20021101

• Reactivation of latent tuberculosis by an inhibitor of inducible nitric oxide synthase in an aerosol murine model.

  Immunology 20021101

• Nitric oxide synthase-mediated phytoalexin accumulation in soybean cotyledons in response to the Diaporthe phaseolorum f. sp. meridionalis elicitor.

  Plant physiology 20021101

• Bone healing regulated by nitric oxide: an experimental study in rats.

  Clinical orthopaedics and related research 20021101

• Loss of retinal ganglion cells following retinal ischemia: the role of inducible nitric oxide synthase.

  Experimental eye research 20021101

• Glycation by ascorbic acid causes loss of activity of ribulose-1,5-bisphosphate carboxylase/oxygenase and its increased susceptibility to proteases.

  Plant & cell physiology 20021101

• [Inducible nitric oxide synthase induces beta-amyloid neurotoxicity in vivo].

  Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20021101

• The occurrence of a novel hydrophilic hydroperoxide, 3-hydroxy-5-hydroperoxy-2-methyl-5,6-dihydropyran-4-one, as a reactive glycation product in human plasma.

  Biochimica et biophysica acta 20021010

• Effects of aminoguanidine on cerebral ischemia in mice: comparison between mice with and without inducible nitric oxide synthase gene.

  Neuroscience letters 20021004

• Lipopolysaccharide triggers late preconditioning against myocardial infarction via inducible nitric oxide synthase.

  Cardiovascular research 20021001

• Nitric oxide participates in the intestinal pathology associated with murine syngeneic graft-versus-host disease.

  Journal of leukocyte biology 20021001

• Reduced hepatotoxicity of acetaminophen in mice lacking inducible nitric oxide synthase: potential role of tumor necrosis factor-alpha and interleukin-10.

  Toxicology and applied pharmacology 20021001

• Evodia rutaecarpa protects against circulation failure and organ dysfunction in endotoxaemic rats through modulating nitric oxide release.

  The Journal of pharmacy and pharmacology 20021001

• Paracellular tightness and catabolism restrict histamine permeation in the proximal colon of pigs.

  Pflugers Archiv : European journal of physiology 20021001

• Gender difference regarding selenium penetration into the mouse brain.

  Biological trace element research 20021001

• [Prevention and treatment of diabetic neuropathy].

  Nihon rinsho. Japanese journal of clinical medicine 20021001

• Comparison of Lp82- and m-calpain-mediated proteolysis during cataractogenesis in Shumiya cataract rat (SCR).

  Current eye research 20021001

• The effect of cyclosporin A on morphine tolerance and dependence: involvement of L-arginine/nitric oxide pathway.

  European journal of pharmacology 20020927

• Inducible nitric oxide synthase expression in the ischemic core and penumbra after transient focal cerebral ischemia in mice.

  Life sciences 20020913

• Evidence for the existence of two distinct functions for the inducible NO synthase in the rat kidney: effect of aminoguanidine in rats with 5/6 ablation.

  Journal of the American Society of Nephrology : JASN 20020901

• Peroxynitrite induces formation of N( epsilon )-(carboxymethyl) lysine by the cleavage of Amadori product and generation of glucosone and glyoxal from glucose: novel pathways for protein modification by peroxynitrite.

  Diabetes 20020901

• Effect of nitric oxide synthase inhabitors on ovulation in hCG-stimulated mares.

  Theriogenology 20020901

• Abrogation of bleomycin-induced lung fibrosis by nitric oxide synthase inhibitor, aminoguanidine in mice.

  Nitric oxide : biology and chemistry 20020901

• Involvement of semicarbazide-sensitive amine oxidase-mediated deamination in atherogenesis in KKAy diabetic mice fed with high cholesterol diet.

  Diabetologia 20020901

• COX and NOS isoforms involved in acid-induced duodenal bicarbonate secretion in rats.

  Digestive diseases and sciences 20020901

• [Aminoguanidine and other AGE inhibitors].

  Nihon rinsho. Japanese journal of clinical medicine 20020901

• [OPB-9195].

  Nihon rinsho. Japanese journal of clinical medicine 20020901

• Immunosuppressants leflunomide and mycophenolic acid inhibit fibroblast IL-6 production by distinct mechanisms.

  Cytokine 20020821

• Efficient in vitro lowering of carbonyl stress by the glyoxalase system in conventional glucose peritoneal dialysis fluid.

  Kidney international 20020801

• Discovery of novel inhibitors of inducible nitric oxide synthase.

  The Journal of pharmacy and pharmacology 20020801

• Do endogenous opioids contribute to the bradycardia of rats with obstructive cholestasis?

  Fundamental & clinical pharmacology 20020801

• The temporal relationship between bacterial lipopolysaccharide and monocrotaline exposures influences toxicity: shift in response from hepatotoxicity to nitric oxide-dependent lethality.

  Journal of toxicology and environmental health. Part A 20020726

• Differential activity of NO synthase inhibitors as chemopreventive agents in a primary rat tracheal epithelial cell transformation system.

  Neoplasia (New York, N.Y.) 20020701

• Expression of the slit-diaphragm protein, nephrin, in experimental diabetic nephropathy: differing effects of anti-proteinuric therapies.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020701

• Effects of nitric oxide synthase inhibitors on the febrile response to muramyl dipeptide and lipopolysaccharide in rats.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20020701

• Organ damage in zymosan-induced multiple organ dysfunction syndrome in mice is not mediated by inducible nitric oxide synthase.

  Critical care medicine 20020701

• Protective effect of aminoguanidine against paraquat-induced oxidative stress in the lung of mice.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020701

• Aminoguanidine pyridoxal adduct is superior to aminoguanidine for preventing diabetic nephropathy in mice.

  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20020701

• Aminoguanidine, an inducible nitric oxide synthase inhibitor, plus N-acetylcysteine treatment reduce the lipopolysaccharide-augmented hepatotoxicity in rats with cirrhosis.

  Human & experimental toxicology 20020701

• Oxidative stress-inducing carbonyl compounds from common foods: novel mediators of cellular dysfunction.

  Molecular medicine (Cambridge, Mass.) 20020701

• NO-ergic mechanisms are implicated in a disturbed cardiac rhythm after systemic application of lipopolysaccharide E. coli to rats.

  Autonomic neuroscience : basic & clinical 20020628

• Anticonvulsant effects of cyclosporin A on pentylenetetrazole-induced seizure and kindling: modulation by nitricoxidergic system.

  Brain research 20020607

• Pharmacological preconditioning with resveratrol: role of nitric oxide.

  American journal of physiology. Heart and circulatory physiology 20020601

• Pharmacological preconditioning with resveratrol: an insight with iNOS knockout mice.

  American journal of physiology. Heart and circulatory physiology 20020601

• Nitric oxide production is maintained in exercising swine with chronic left ventricular dysfunction.

  American journal of physiology. Heart and circulatory physiology 20020601

• Promising effects of ischemic preconditioning in renal transplantation.

  Kidney international 20020601

• Regulation of cyclooxygenase-2 by nitric oxide in activated hepatic macrophages during acute endotoxemia.

  Journal of leukocyte biology 20020601

• Role of inducible nitric oxide synthase in skeletal adaptation to acute increases in mechanical loading.

  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20020601

• Dual effect of nitric oxide in articular inflammatory pain in zymosan-induced arthritis in rats.

  British journal of pharmacology 20020601

• Conversion of Amadori products of the Maillard reaction to N(epsilon)-(carboxymethyl)lysine by short-term heating: possible detection of artifacts by immunohistochemistry.

  Laboratory investigation; a journal of technical methods and pathology 20020601

• Inducible nitric oxide synthase pathway in the central nervous system and vasopressin release during experimental septic shock.

  Critical care medicine 20020601

• Yet another potential role for nitric oxide in the pathophysiology of septic shock.

  Critical care medicine 20020601

• Effect of BRX-220 against peripheral neuropathy and insulin resistance in diabetic rat models.

  Annals of the New York Academy of Sciences 20020601

• Protective effect of aminoguanidine against nephrotoxicity induced by cisplatin in normal rats.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020601

• Protective effect of L-arginine against nephrotoxicity induced by cyclosporine in normal rats.

  Pharmacological research 20020601

• An investigation into the mechanisms mediating plasma lipoprotein-potentiated beta-amyloid fibrillogenesis.

  FEBS letters 20020508

• Dual role for nitric oxide in paracoccidioidomycosis: essential for resistance, but overproduction associated with susceptibility.

  Journal of immunology (Baltimore, Md. : 1950) 20020501

• Advanced glycation end product precursors impair epidermal growth factor receptor signaling.

  Diabetes 20020501

• Expression of MAPkinases (Erk1/2) during decidualization in the rat: regulation by progesterone and nitric oxide.

  Molecular human reproduction 20020501

• Cardiac response to nitric oxide synthase inhibition using aminoguanidine in a rat model of endotoxemia.

  Shock (Augusta, Ga.) 20020501

• Temporal and segmental distribution of constitutive and inducible nitric oxide synthases after traumatic spinal cord injury: effect of aminoguanidine treatment.

  Journal of neurotrauma 20020501

• Effect of age receptor blocker and/or anti-inflammatory coadministration in relation to glycation, oxidative stress and cytokine production in stz diabetic rats.

  Pharmacological research 20020501

• Delayed cardioprotective effects of exercise in dogs are aminoguanidine sensitive: possible involvement of nitric oxide.

  Clinical science (London, England : 1979) 20020401

• Pimagedine: a novel therapy for diabetic nephropathy.

  Expert opinion on investigational drugs 20020401

• Ischemia/reperfusion-induced increase in the hepatic level of prostacyclin is mainly mediated by activation of capsaicin-sensitive sensory neurons in rats.

  The Journal of laboratory and clinical medicine 20020401

• Long-term observations on the reversibility of cochlear dysfunction after transient ischemia.

  Hearing research 20020401

• N(omega)-nitro-L-arginine inhibits inducible HSP-70 via Ca(2+), PKC, and PKA in human intestinal epithelial T84 cells.

  American journal of physiology. Gastrointestinal and liver physiology 20020301

• Pyridoxamine inhibits early renal disease and dyslipidemia in the streptozotocin-diabetic rat.

  Kidney international 20020301

• The role of inducible nitric oxide synthase in lipopolysaccharide-mediated hyporeactivity to vasoconstrictors differs among isolated rat arteries.

  Clinical science (London, England : 1979) 20020301

• Infection with Brugia microfilariae induces apoptosis of CD4(+) T lymphocytes: a mechanism of immune unresponsiveness in filariasis.

  European journal of immunology 20020301

• A study on the relationship between homocysteine and diabetic nephropathy in rats.

  Pharmacological research 20020301

• Effect of inhibitors of nitric oxide synthase on acetaminophen-induced hepatotoxicity in mice.

  Nitric oxide : biology and chemistry 20020301

• Nitric oxide modulation of neurally induced proximal tubular fluid reabsorption in the rat.

  Hypertension (Dallas, Tex. : 1979) 20020301

• Inhibition of inducible nitric oxide synthase during high dietary salt intake.

  American journal of hypertension 20020301

• Diabetes-induced nitrative stress in the retina, and correction by aminoguanidine.

  Journal of neurochemistry 20020301

• Effects of nitric oxide synthase inhibitors and melatonin on the hyperglycemic response to streptozotocin in rats.

  Vascular pharmacology 20020301

• Expression of diamine oxidase (histaminase) in guinea-pig tissues.

  European journal of pharmacology 20020222

• Inducible nitric oxide synthase plays a role in LPS-induced hyperglycemia and insulin resistance.

  American journal of physiology. Endocrinology and metabolism 20020201

• Synthesis, structure investigations, and antimicrobial activity of selected s-trans-6-aryl-4-isopropyl-2-[2-[(E)-1-phenylalkylidene]-(E)-hydrazino]-1,4-dihydropyrimidine hydrochlorides.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20020201

• Generation of superoxide anions during the reaction of guanidino compounds with methylglyoxal.

  Chemical & pharmaceutical bulletin 20020201

• Identification of alpha-dicarbonyl scavengers for cellular protection against carbonyl stress.

  Biochemical pharmacology 20020201

• Involvement of neuronal nitric oxide synthase in restraint stress-induced fever in rats.

  Physiology & behavior 20020201

• Circadian variation in the effects of nitric oxide synthase inhibitors on body temperature, feeding and activity in rats.

  Pflugers Archiv : European journal of physiology 20020201

• [Effect of wenjingtong composita on blood glucose and advanced glycosylation end products in sciatic nerve of streptozotocin-induced diabetic rats].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20020201

• Abnormal vascular function and hypertension in mice deficient in estrogen receptor beta.

  Science (New York, N.Y.) 20020118

• Aminoguanidine renders inducible nitric oxide synthase knockout mice more susceptible to Salmonella typhimurium infection.

  FEMS microbiology letters 20020102

• High glucose increases inducible NO production in cultured rat mesangial cells. Possible role in fibronectin production.

  Nephron 20020101

• Peri-ischemic aminoguanidine fails to ameliorate neurologic and histopathologic outcome after transient spinal cord ischemia.

  Journal of neurosurgical anesthesiology 20020101

• Immune modulation by fish kinetoplastid parasites: a role for nitric oxide.

  Parasitology 20020101

• Ileal luminal nitric oxide synthase inhibitors and E. coli lipopolysaccharide effects in the anesthetized rat.

  Digestive diseases and sciences 20020101

• Effects of aminoguanidine and tolrestat on the development of ocular and renal structural changes in experimental diabetic rats.

  Diabetes, obesity & metabolism 20020101

• Effect of treating streptozotocin-induced diabetic rats with sorbinil, myo-inositol or aminoguanidine on endoneurial blood flow, motor nerve conduction velocity and vascular function of epineurial arterioles of the sciatic nerve.

  International journal of experimental diabetes research 20020101

• Effective inhibition of nitric oxide production by aminoguanidine does not reverse hypotension in endotoxaemic rats.

  Acta anaesthesiologica Scandinavica 20020101

• Nitric oxide in experimental aneurysm formation: early events and consequences of nitric oxide inhibition.

  Annals of vascular surgery 20020101

• Effects of aminoguanidine on lipid and protein oxidation in diabetic rat kidneys.

  International journal of experimental diabetes research 20020101

• The effects of aminoguanidine on renal changes in a baboon model of Type 1 diabetes.

  Journal of diabetes and its complications 20020101

• Hyperbaric oxygen increases the lung's susceptibility to inhaled lipopolysaccharide in mice.

  Lung 20020101

• The effects of nitric oxide donors and inhibitors on neutrophil functions in Behçet's disease.

  Clinical and experimental rheumatology 20020101

• Effects of inhibition of glycation and oxidative stress on the development of diabetic nephropathy in rats.

  Journal of diabetes and its complications 20020101

• Healing of duodenal ulcers is not impaired by indomethacin or rofecoxib, the selective COX-2 inhibitor, in rats.

  Digestion 20020101

• Adrenomedullin: a cardiac depressant factor in septic shock.

  Journal of cardiac surgery 20020101

• Inhibition of nNOS and iNOS following hypoxia-ischaemia improves long-term outcome but does not influence the inflammatory response in the neonatal rat brain.

  Developmental neuroscience 20020101

• In vivo inhibition of inducible nitric oxide synthase decreases lung injury induced by Toxocara canis in experimentally infected rats.

  Parasite immunology 20020101

• Nitric oxide mediated modulation of free radical generation response in the rat polymorphonuclear leukocytes: a flowcytometric study.

  Methods in cell science : an official journal of the Society for In Vitro Biology 20020101

• Effects of ageing and arthritic disease on nitric oxide production by human articular chondrocytes.

  Experimental & molecular medicine 20011231

• Chelating activity of advanced glycation end-product inhibitors.

  The Journal of biological chemistry 20011228

• Expression of inducible nitric oxide synthase depresses beta-adrenergic-stimulated calcium release from the sarcoplasmic reticulum in intact ventricular myocytes.

  Circulation 20011211

• Effects of erythropoietin and aminoguanidine on red blood cell deformability in diabetic azotemic and uremic patients.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20011201

• Suppression of intestinal polyposis in Apc(Min/+) mice by inhibiting nitric oxide production.

  Cancer research 20011201

• A critical evaluation of the brain efflux index method as applied to the nitric oxide synthase inhibitor, aminoguanidine.

  Biopharmaceutics & drug disposition 20011201

• Advanced glycation end products in Descemet's membrane and their effect on corneal endothelial cell.

  Current eye research 20011201

• L-citrulline mediated relaxation in the control and lipopolysaccharide-treated rat aortic rings.

  European journal of pharmacology 20011109

• Correction of early subnormal superior hemiretinal DeltaPO(2) predicts therapeutic efficacy in experimental diabetic retinopathy.

  Investigative ophthalmology & visual science 20011101

• An inhibitor of inducible nitric oxide synthase decreases forearm blood flow in patients with congestive heart failure.

  Journal of the American College of Cardiology 20011101

• Nitric oxide inhibitors ameliorate indomethacin-induced enteropathy in rats.

  Digestive diseases and sciences 20011101

• Modulation of leukocyte-endothelium interaction by nitric oxide synthase inhibitors: effects on leukocyte adhesion in endotoxin-induced uveitis.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20011101

• Effects of aminoguanidine and N(omega)-nitro-L-arginine methyl ester on vascular hyporeactivity induced by endotoxaemia.

  The European journal of surgery = Acta chirurgica 20011101

• Bothrops asper and Bothrops jararaca snake venoms trigger microbicidal functions of peritoneal leukocytes in vivo.

  Toxicon : official journal of the International Society on Toxinology 20011001

• Aminoguanidine ameliorates overexpression of prosclerotic growth factors and collagen deposition in experimental diabetic nephropathy.

  Journal of the American Society of Nephrology : JASN 20011001

• Lipopolysaccharide-induced increase of prostaglandin E(2) is mediated by inducible nitric oxide synthase activation of the constitutive cyclooxygenase and induction of membrane-associated prostaglandin E synthase.

  Journal of immunology (Baltimore, Md. : 1950) 20011001

• Ischemia-reperfusion injury of the cochlea: effects of an iron chelator and nitric oxide synthase inhibitors.

  Hearing research 20011001

• Methylamine and benzylamine induced hypophagia in mice: modulation by semicarbazide-sensitive benzylamine oxidase inhibitors and aODN towards Kv1.1 channels.

  British journal of pharmacology 20011001

• Aminoguanidine and aortic wall mechanics, structure, and composition in aged rats.

  Hypertension (Dallas, Tex. : 1979) 20011001

• The effects of cervical application of inhibitors of inducible nitric oxide synthase, cyclooxygenase-1, and cyclooxygenase-2 on delivery in rats.

  American journal of obstetrics and gynecology 20011001

• L-Arginine is not the limiting factor for nitric oxide synthesis by human alveolar macrophages in vitro.

  The European respiratory journal 20011001

• Retinal glial cell immunoreactivity and neuronal cell changes in rats with STZ-induced diabetes.

  Current eye research 20011001

• Involvement of inducible nitric oxide synthase in cataract formation in Shumiya cataract rat (SCR).

  Current eye research 20011001

• Functional role of inducible nitric oxide synthase on mouse colonic motility.

  Neuroscience letters 20010928

• Peripheral nitric oxide in carrageenan-induced inflammation.

  Brain research 20010907

• Involvement of nitric oxide on the peritoneal neutrophil influx induced by staphylococcal enterotoxin B in mouse.

  Toxicon : official journal of the International Society on Toxinology 20010901

• Oxidative DNA damage induced by high glucose and its suppression in human umbilical vein endothelial cells.

  Mutation research 20010901

• Interactions between nitric oxide and renal nerves in the excretion of a saline load in obese Zucker rats.

  Clinical science (London, England : 1979) 20010901

• Effect of chronic aminoguanidine treatment on age-related glycation, glycoxidation, and collagen cross-linking in the Fischer 344 rat.

  The journals of gerontology. Series A, Biological sciences and medical sciences 20010901

• Myocytes isolated from rejecting transplanted rat hearts exhibit a nitric oxide-mediated reduction in the calcium current.

  Journal of molecular and cellular cardiology 20010901

• Role of nitric oxide in histamine release from human basophils and rat peritoneal mast cells.

  European journal of pharmacology 20010817

• Lipopolysaccharide and interferon-gamma-induced nitric oxide production and protein oxidation in mouse peritoneal macrophages are affected by glutathione peroxidase-1 gene knockout.

  Free radical biology & medicine 20010815

• Inhibition of salivary secretion by lipopolysaccharide: possible role of prostaglandins.

  American journal of physiology. Endocrinology and metabolism 20010801

• Nitric oxide promotes germ cell necrosis in the delayed phase after experimental testicular torsion of rat.

  Biology of reproduction 20010801

• Nitric oxide mediates endotoxin-induced hypertriglyceridemia through its action on skeletal muscle lipoprotein lipase.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010801

• Effects of nitric oxide synthase inhibitors on vascular hyperpermeability with thermal injury in mice.

  Nitric oxide : biology and chemistry 20010801

• Cirrhosis serum induces a nitric oxide-associated vascular hyporeactivity of aortic segments from healthy rats in vitro.

  European journal of gastroenterology & hepatology 20010801

• The effect of aminoguanidine on diabetes-induced inactivation of kidney Na(+),K(+)- ATPase in rats.

  Pharmacological research 20010801

• Nitric oxide mediates the inhibition of neutrophil migration induced by systemic administration of LPS.

  Inflammation 20010801

• Inhibitory effect of aminoguanidine on bleomycin-induced pulmonary toxicity in rat.

  Acta pharmacologica Sinica 20010801

• Pharmacological inhibition of diabetic retinopathy: aminoguanidine and aspirin.

  Diabetes 20010701

• Endotoxin-induced vascular hyporesponsiveness in rat aorta: in vitro effect of aminoguanidine.

  Pharmacological research 20010701

• Inducible nitric oxide synthase knockout mice exhibit resistance to the multiple organ failure induced by zymosan.

  Shock (Augusta, Ga.) 20010701

• Contribution of endothelial nitric oxide synthase in the blunted renal responses to volume expansion in diabetic rats.

  Experimental physiology 20010701

• Changes in polyamines, auxins and peroxidase activity during in vitro rooting of Fraxinus angustifolia shoots: an auxin-independent rooting model.

  Tree physiology 20010701

• Glycation during human dermal intrinsic and actinic ageing: an in vivo and in vitro model study.

  The British journal of dermatology 20010701

• Inducible nitric oxide production is an adaptation to cardiopulmonary bypass-induced inflammatory response.

  The Annals of thoracic surgery 20010701

• Role of endothelial nitric oxide synthase in estrogen-induced osteogenesis.

  Bone 20010701

• 7-Nitroindazole, but not aminoguanidine, attenuates the acute inflammatory responses and brain injury during the early phase of Escherichia coli meningitis in the newborn piglet.

  Biology of the neonate 20010701

• Neuroprotective effect of aminoguanidine on transient focal ischaemia in the rat brain.

  Brain research 20010629

• Involvement of nitric oxide in pollen-induced biphasic nasal blockage in sensitised guinea pigs.

  European journal of pharmacology 20010629

• Minimal amidine structure for inhibition of nitric oxide biosynthesis.

  Biochemical pharmacology 20010615

• Effects of aminoguanidine on nitric oxide production induced by inflammatory cytokines and endotoxin in cultured rat hepatocytes.

  World journal of gastroenterology 20010615

• TNF-alpha controls intracellular mycobacterial growth by both inducible nitric oxide synthase-dependent and inducible nitric oxide synthase-independent pathways.

  Journal of immunology (Baltimore, Md. : 1950) 20010601

• Advanced glycation: an important pathological event in diabetic and age related ocular disease.

  The British journal of ophthalmology 20010601

• Spontaneous and receptor-controlled soluble guanylyl cyclase activity in anterior pituitary cells.

  Molecular endocrinology (Baltimore, Md.) 20010601

• Amyloid beta-peptide induces nitric oxide production in rat hippocampus: association with cholinergic dysfunction and amelioration by inducible nitric oxide synthase inhibitors.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010601

• Potent and selective inhibition of the human Na+/H+ exchanger isoform NHE1 by a novel aminoguanidine derivative T-162559.

  European journal of pharmacology 20010518

• Aminoguanidine prevented the impairment of learning behavior and hippocampal long-term potentiation following transient cerebral ischemia.

  Behavioural brain research 20010501

• Alterations in spontaneous contractions in vitro after repeated inflammation of rat distal colon.

  American journal of physiology. Gastrointestinal and liver physiology 20010501

• Effect of aminoguanidine, a nitric oxide synthase inhibitor, on ocular infection with herpes simplex virus in Balb/c mice.

  Investigative ophthalmology & visual science 20010501

• Peroxynitrite mediates cytokine-induced IL-8 gene expression and production by human leukocytes.

  Journal of leukocyte biology 20010501

• Role of inducible nitric oxide synthase in the pulmonary vascular response to birth-related stimuli in the ovine fetus.

  Circulation research 20010413

• Glutathione depletion, lipid peroxidation and mitochondrial dysfunction are induced by chronic stress in rat brain.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010401

• Down regulation of interleukin 1beta production in human osteoarthritic synovial tissue and cartilage cultures by aminoguanidine.

  Annals of the rheumatic diseases 20010401

• The lung is the major site that produces nitric oxide to induce acute pulmonary oedema in endotoxin shock.

  Clinical and experimental pharmacology & physiology 20010401

• N-Acetylaspartate, a marker of both cellular dysfunction and neuronal loss: its relevance to studies of acute brain injury.

  Journal of neurochemistry 20010401

• Comparison of cardiac and regional hemodynamic responses to N-methyl-L-arginine and aminoguanidine infusions in conscious pigs.

  Journal of cardiovascular pharmacology 20010401

• Role of nitric oxide in the secondary expansion of a cortical brain lesion from cold injury.

  Journal of neurotrauma 20010401

• Glycation cross-links inhibit matrix metalloproteinase-2 activation in vascular smooth muscle cells cultured on collagen lattice.

  Diabetologia 20010401

• Two different NO-dependent mechanisms account for the low virulence of a non-mycelial morphological mutant of Candida albicans.

  Medical microbiology and immunology 20010401

• Effect of LPS on the permeability of the blood-brain barrier to insulin.

  Brain research 20010330

• The timing of endothelin and nitric oxide inhibition affects survival in a mice model of septic shock.

  European journal of pharmacology 20010302

• Aminoguanidine and ramipril prevent diabetes-induced increases in protein kinase C activity in glomeruli, retina and mesenteric artery.

  Clinical science (London, England : 1979) 20010301

• Nitric oxide synthases in pregnant rat uterus.

  Reproduction (Cambridge, England) 20010301

• Inducible nitric oxide synthase inhibition delays death of rabies virus-infected mice.

  Journal of medical microbiology 20010301

• Inhibition of inducible nitric oxide synthase limits nitric oxide production and experimental aneurysm expansion.

  Journal of vascular surgery 20010301

• Advanced glycation end-products are responsible for the impairment of corpus cavernosal smooth muscle relaxation seen in diabetes.

  BJU international 20010301

• Protective effect of aminoguanidine upon capillary and submesothelial anionic sites.

  Microvascular research 20010301

• Inhibition of nitric oxide synthesis by aminoguanidine increases intestinal damage in the acute phase of rat TNB-colitis.

  European journal of clinical investigation 20010301

• Nitric oxide is involved in the immunomodulating activities of acidic polysaccharide from Panax ginseng.

  Planta medica 20010301

• Effects of aminoguanidine and desferrioxamine on some vascular and biochemical changes associated with streptozotocin-induced hyperglycaemia in rats.

  Pharmacological research 20010301

• Nitric oxide participates in cataract development in selenite-treated rats.

  Current eye research 20010301

• Mechanisms of circulatory and intestinal barrier dysfunction during whole body hyperthermia.

  American journal of physiology. Heart and circulatory physiology 20010201

• Intestinal ischemia induces late preconditioning against myocardial infarction: a role for inducible nitric oxide synthase.

  Cardiovascular research 20010201

• Glycoxidation and lipid peroxidation of low-density lipoprotein can synergistically enhance atherogenesis.

  Cardiovascular research 20010201

• On the anti-aging activities of aminoguanidine and N-t-butylhydroxylamine.

  Mechanisms of ageing and development 20010201

• Ramipril and aminoguanidine restore renal lysosomal processing in streptozotocin diabetic rats.

  Diabetologia 20010201

• Antioxidants, vitamin C and dithiothreitol, activate membrane-bound guanylate cyclase in PC12 cells.

  The Journal of pharmacy and pharmacology 20010201

• Dependence of soluble guanylyl cyclase activity on calcium signaling in pituitary cells.

  The Journal of biological chemistry 20010105

• Expression of intercellular adhesion molecule-1 induced by high glucose concentrations in human aortic endothelial cells.

  Life sciences 20010105

• Diabetic nephropathy and advanced glycation end products.

  Contributions to nephrology 20010101

• The role of nitric oxide in diaphragmatic dysfunction in endotoxemic rats.

  Muscle & nerve 20010101

• Aminoguanidine does not influence tissue extravasation of albumin in endotoxaemic rats.

  Acta anaesthesiologica Scandinavica 20010101

• Levels of nitric oxide in the heart after experimental myocardial ischemia.

  Journal of cardiovascular pharmacology 20010101

• Antiapoptotic role of endogenous nitric oxide in human melanoma cells.

  Cancer research 20010101

• Differential roles of iNOS and nNOS at rostral ventrolateral medulla during experimental endotoxemia in the rat.

  Shock (Augusta, Ga.) 20010101

• Renoprotective effects of a novel inhibitor of advanced glycation.

  Diabetologia 20010101

• Association of nitric oxide production and apoptosis in a model of experimental nephropathy.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010101

• Differing effects of two nitric oxide synthase inhibitors on experimental colitis.

  Hepato-gastroenterology 20010101

• The effect of advanced glycation end-products and aminoguanidine on TNFalpha production by rat peritoneal macrophages.

  Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20010101

• Effect of aminoguanidine and copper(II) ions on the formation of advanced glycosylation end products. In vitro study on human serum albumin.

  Arzneimittel-Forschung 20010101

• Structural and functional alterations of the peritoneum after prolonged exposure to dialysis solutions: role of aminoguanidine.

  Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20010101

• Phenanthrenequinone disrupts progesterone production in rat luteal cells.

  Reproductive toxicology (Elmsford, N.Y.) 20010101

• Intestinal protection by lafutidine, a histamine H(2)-receptor antagonist, against indomethacin-induced damage in rats--role of endogenous nitric oxide.

  Medical science monitor : international medical journal of experimental and clinical research 20010101

• Estrogenic status influences nitric oxide-regulated TNF-alpha release from human peripheral blood monocytes.

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20010101

• Nitric oxide is generated in smooth muscle layer by neurokinin A and counteracts constriction in guinea pig airway.

  Nitric oxide : biology and chemistry 20010101

• Nitric oxide- and oxygen-derived free radical generation from control and lipopolysaccharide-treated rat polymorphonuclear leukocyte.

  Nitric oxide : biology and chemistry 20010101

• Increased retinal endothelial cell monolayer permeability induced by the diabetic milieu: role of advanced non-enzymatic glycation and polyol pathway activation.

  Diabetes/metabolism research and reviews 20010101

• Beneficial effect of nitric oxide synthase inhibitor on hepatotoxicity induced by allyl alcohol.

  Journal of biochemical and molecular toxicology 20010101

• [Renal effects of the chronic inhibition of nitric oxide synthesis in cirrhotic rats with ascites].

  Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20010101

• [Antioxidant and anti-AGE therapeutics: evaluation and perspectives].

  Journal de la Societe de biologie 20010101

• Effects of aminoguanidine and meloxicam on nitric oxide and prostaglandin E production induced by lipopolysaccharide in the hypothalamus and anterior pituitary of the rat.

  Neuroimmunomodulation 20010101

• Effects of aminoguanidine on glomerular basement membrane thickness and anionic charge in a diabetic rat model.

  International journal of experimental diabetes research 20010101

• Endotoxin augments cerebral hyperemic response to halothane by inducing nitric oxide synthase and cyclooxygenase.

  Anesthesia and analgesia 20001001

• Glycation amplifies lipoprotein(a)-induced alterations in the generation of fibrinolytic regulators from human vascular endothelial cells.

  Atherosclerosis 20000601

• Roles of endogenous gamma interferon and macrophage microbicidal mechanisms in host response to chemotherapy in experimental visceral leishmaniasis.

  Infection and immunity 20000101

• Nitric oxide synthase inhibitors attenuate ozone-induced airway inflammation in guinea pigs. Possible role of interleukin-8.

  American journal of respiratory and critical care medicine 20000101

• Dual action of nitric oxide in pathogenesis of indomethacin-induced small intestinal ulceration in rats.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 19990901

• Nitric oxide, superoxide radicals and mast cells in pathogenesis of indomethacin-induced small intestinal lesions in rats.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 19990301

• Reduction of myocardial infarct size by inhibition of inducible nitric oxide synthase.

  American journal of hypertension 19990201

• Delayed treatment with aminoguanidine decreases focal cerebral ischemic damage and enhances neurologic recovery in rats.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 19981001

• Effects of aminoguanidine on latent murine tuberculosis.

  Journal of immunology (Baltimore, Md. : 1950) 19980215

• Role of inducible nitric oxide synthase in regulation of pulmonary vascular tone in the late gestation ovine fetus.

  The Journal of clinical investigation 19980101

• [Involvement of nitric oxide, which was synthesized by constitutive nitric oxide synthase, and prostaglandin on diarrhea induced by castor oil in rats].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 19970801

• Contraction and relaxation of aortas from diabetic rats: effects of chronic anti-oxidant and aminoguanidine treatments.

  Naunyn-Schmiedeberg's archives of pharmacology 19960401

• Effects of nitric oxide synthase inhibitors on murine infection with Mycobacterium tuberculosis.

  Infection and immunity 19950201

• Regulation of gastric mucosal diamine oxidase activity by gastrin.

  FEBS letters 19920728

• Mechanistic studies of advanced glycosylation end product inhibition by aminoguanidine.

  Diabetes 19920101

• Aminoguanidine effects on nerve blood flow, vascular permeability, electrophysiology, and oxygen free radicals.

  Proceedings of the National Academy of Sciences of the United States of America 19910715